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Gene: HDC (histidine decarboxylase) Homo sapiens
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Symbol: HDC
Name: histidine decarboxylase
Description: Exhibits histidine decarboxylase activity. Involved in histamine biosynthetic process and histidine catabolic process. Predicted to localize to the cytosol. Implicated in Gilles de la Tourette syndrome; asthma; and rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC163399
Orthologs:
Mus musculus (house mouse) : Hdc (histidine decarboxylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hdc (histidine decarboxylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdc (histidine decarboxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : HDC (histidine decarboxylase)
Canis lupus familiaris (dog) : HDC (histidine decarboxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdc (histidine decarboxylase)
Sus scrofa (pig) : HDC (histidine decarboxylase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381550,241,945 - 50,266,049 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371550,534,144 - 50,558,162 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361548,321,436 - 48,345,218 (-)NCBINCBI36hg18NCBI36
Build 341548,321,442 - 48,345,214NCBI
Celera1527,426,734 - 27,450,752 (-)NCBI
Cytogenetic Map15q21.2NCBI
HuRef1527,365,086 - 27,389,097 (-)NCBIHuRef
CHM1_11550,652,084 - 50,676,103 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HDC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736253
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.