GWAS799601_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS799601_H (low density lipoprotein triglyceride measurement QTL GWAS799601 (human)) Homo sapiens

Symbol: GWAS799601_H
Name: low density lipoprotein triglyceride measurement QTL GWAS799601 (human)
RGD ID: 407150625
Trait: low density lipoprotein triglyceride measurement
Measurement Type: blood low density lipoprotein triglyceride level   (CMO:0002687)    
LOD Score: Not Available
P Value: 1.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,279,783 - 58,279,784RGD_MAPPER_PIPELINEGRCh38
GRCh371558,571,982 - 58,571,983RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS799601_HHumanblood low density lipoprotein triglyceride level  IAGPrs11854318405850206Based on the EFO term IDGWAS_CATALOGPMID:34610981

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS799601_HHumanlow density lipoprotein triglyceride measurement  IAGPrs11854318405850206 GWAS_CATALOGPMID:34610981
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs11854318)
Human AssemblyChrPosition (strand)Source
GRCh381558,279,783 - 58,279,784RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407282342GWAS931318_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS931318 (human)3e-52triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155827978358279784Human
407151525GWAS800501_Hlow density lipoprotein triglyceride measurement QTL GWAS800501 (human)1e-10low density lipoprotein triglyceride measurementblood low density lipoprotein triglyceride level (CMO:0002687)155827978358279784Human
407268359GWAS917335_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS917335 (human)1e-52triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155827978358279784Human
407150625GWAS799601_Hlow density lipoprotein triglyceride measurement QTL GWAS799601 (human)1e-09low density lipoprotein triglyceride measurementblood low density lipoprotein triglyceride level (CMO:0002687)155827978358279784Human
407191011GWAS839987_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS839987 (human)3e-68triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155827978358279784Human
407084555GWAS733531_Hphospholipids:total lipids ratio QTL GWAS733531 (human)7e-21phospholipids:total lipids ratio155827978358279784Human
407310991GWAS959967_Htriglyceride measurement, very low density lipoprotein cholesterol measurement QTL GWAS959967 (human)8e-65triglyceride measurement, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155827978358279784Human
407288271GWAS937247_Htriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS937247 (human)6e-51triglycerides:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)155827978358279784Human
407293900GWAS942876_Hcholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS942876 (human)1e-75cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155827978358279784Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407039631GWAS688607_Hsaturated fatty acids measurement QTL GWAS688607 (human)3e-13saturated fatty acids measurement 155827978358279784Human
407152906GWAS801882_Hlow density lipoprotein triglyceride measurement QTL GWAS801882 (human)2e-09low density lipoprotein triglyceride measurementblood low density lipoprotein triglyceride level (CMO:0002687)155827978358279784Human
407090899GWAS739875_Hcholesterol to total lipids in IDL percentage QTL GWAS739875 (human)2e-29cholesterol to total lipids in IDL percentage 155827978358279784Human
407079314GWAS728290_Hcholesteryl esters to total lipids in IDL percentage QTL GWAS728290 (human)9e-28cholesteryl esters to total lipids in IDL percentage 155827978358279784Human
407040656GWAS689632_Hvery low density lipoprotein cholesterol measurement QTL GWAS689632 (human)3e-10very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155827978358279784Human
407037361GWAS686337_Htriglycerides in small LDL measurement QTL GWAS686337 (human)6e-14triglycerides in small LDL measurement 155827978358279784Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407030107GWAS679083_Hfatty acid measurement QTL GWAS679083 (human)1e-14fatty acid measurement155827978358279784Human
407152605GWAS801581_Hlow density lipoprotein triglyceride measurement QTL GWAS801581 (human)2e-10low density lipoprotein triglyceride measurementblood low density lipoprotein triglyceride level (CMO:0002687)155827978358279784Human
407030207GWAS679183_Hvery low density lipoprotein cholesterol measurement QTL GWAS679183 (human)6e-13very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155827978358279784Human
407150105GWAS799081_Hlow density lipoprotein triglyceride measurement QTL GWAS799081 (human)5e-10low density lipoprotein triglyceride measurementblood low density lipoprotein triglyceride level (CMO:0002687)155827978358279784Human
407040893GWAS689869_Htotal lipids in small VLDL QTL GWAS689869 (human)9e-10total lipids in small VLDL155827978358279784Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS679083_H GCST90269539 Total fatty acids levels (UKB data field 23442) 88,268 European ancestry individuals A 0.27466 1E-14 14 rs11854318 0.0406793 fatty acid measurement (EFO:0005110)
 PMID:36764567
GWAS679183_H GCST90269525 Concentration of VLDL particles (UKB data field 23428) 88,329 European ancestry individuals A 0.274614 6E-13 12.222 rs11854318 0.0382331 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:36764567
GWAS686337_H GCST90269647 Triglycerides in small LDL (UKB data field 23550) 88,329 European ancestry individuals A 0.274614 6E-14 13.222 rs11854318 0.0389869 triglycerides in small LDL measurement (EFO:0022323)
 PMID:36764567
GWAS688607_H GCST90269545 Saturated fatty acids levels (UKB data field 23448) 88,268 European ancestry individuals A 0.27466 3E-13 12.523 rs11854318 0.0384189 saturated fatty acids measurement (EFO:0022304)
 PMID:36764567
GWAS689632_H GCST90269606 Concentration of small VLDL particles (UKB data field 23509) 88,329 European ancestry individuals A 0.274614 3E-10 9.523 rs11854318 0.0332358 very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:36764567
GWAS689869_H GCST90269607 Total lipids in small VLDL (UKB data field 23510) 88,329 European ancestry individuals A 0.274614 9E-10 9.046 rs11854318 0.0324057 total lipids in small VLDL (EFO:0022148)
 PMID:36764567
GWAS728290_H GCST90269708 Cholesteryl esters to total lipids in IDL percentage (UKB data field 23611) 88,329 European ancestry individuals A 0.274614 9E-28 27.046 rs11854318 0.0568734 cholesteryl esters to total lipids in IDL percentage (EFO:0022247)
 PMID:36764567
GWAS733531_H GCST90269716 Phospholipids to total lipids in medium LDL percentage (UKB data field 23619) 88,329 European ancestry individuals A 0.274614 7E-21 20.155 rs11854318 0.0497292 phospholipids:total lipids ratio (EFO:0020946)
 PMID:36764567
GWAS739875_H GCST90269707 Cholesterol to total lipids in IDL percentage (UKB data field 23610) 88,329 European ancestry individuals A 0.274614 2E-29 28.699 rs11854318 0.0586106 cholesterol to total lipids in IDL percentage (EFO:0022233)
 PMID:36764567
GWAS839987_H GCST90092866 Triglyceride levels in large LDL 115,082 European ancestry individuals G 0.725305 3E-68 67.523 rs11854318 0.0794022 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS917335_H GCST90092829 Triglyceride levels in HDL 115,082 European ancestry individuals G 0.725305 1E-52 52 rs11854318 0.0693779 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS931318_H GCST90092890 Triglyceride levels in LDL 115,082 European ancestry individuals G 0.725305 3E-52 51.523 rs11854318 0.0691697 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS937247_H GCST90092915 Triglycerides to total lipids ratio in medium LDL 115,082 European ancestry individuals G 0.725305 6E-51 50.222 rs11854318 0.0682627 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS942876_H GCST90092947 Cholesteryl esters to total lipids ratio in small HDL 115,082 European ancestry individuals G 0.725305 1E-75 75 rs11854318 0.0835204 cholesteryl esters:total lipids ratio (EFO:0020944)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS959967_H GCST90093038 Triglyceride levels in very small VLDL 115,082 European ancestry individuals G 0.725305 8E-65 64.097 rs11854318 0.0768435 triglyceride measurement (EFO:0004530)
very low density lipoprotein cholesterol measurement (EFO:0008317)
 PMID:35213538
None Available GCST90091714 Postprandial triglycerides levels in medium LDL null A 0.289429952 5E-10 9.302 rs11854318 0.147382 low density lipoprotein triglyceride measurement (EFO:0009946)
 PMID:34610981
None Available GCST90091538 Fasting triglycerides in LDL null A 0.291483312 1E-9 9 rs11854318 0.137013 low density lipoprotein triglyceride measurement (EFO:0009946)
 PMID:34610981
None Available GCST90091693 Postprandial triglycerides levels in large LDL null A 0.289478381 1E-10 10 rs11854318 0.151992 low density lipoprotein triglyceride measurement (EFO:0009946)
 PMID:34610981
None Available GCST90091678 Postprandial triglycerides in LDL null A 0.289478381 2E-9 8.699 rs11854318 0.142287 low density lipoprotein triglyceride measurement (EFO:0009946)
 PMID:34610981
None Available GCST90091553 Fasting triglycerides levels in large LDL null A 0.291483312 2E-10 9.699 rs11854318 0.144517 low density lipoprotein triglyceride measurement (EFO:0009946)
 PMID:34610981
Database Acc Id Source(s)
GWAS Catalog GCST90091538 GWAS Catalog

RGD Curation Notes
Note Type Note Reference