GWAS612468_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS612468_H (neutrophil count, eosinophil count QTL GWAS612468 (human)) Homo sapiens

Symbol: GWAS612468_H
Name: neutrophil count, eosinophil count QTL GWAS612468 (human)
RGD ID: 406963492
Trait: eosinophil quantity   (VT:0002602)    
neutrophil quantity   (VT:0000222)    
Measurement Type: blood eosinophil count   (CMO:0000033)    
blood neutrophil count   (CMO:0000030)    
LOD Score: Not Available
P Value: 1.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381541,939,155 - 41,939,156RGD_MAPPER_PIPELINEGRCh38
GRCh371542,231,353 - 42,231,354RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS612468_HHumanblood eosinophil count  IAGPrs12101888405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252
GWAS612468_HHumanblood neutrophil count  IAGPrs12101888405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS612468_HHumaneosinophil quantity  IAGPrs12101888405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252
GWAS612468_HHumanneutrophil quantity  IAGPrs12101888405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS612468_HHumaneosinophil count  IAGPrs12101888405850206 GWAS_CATALOGPMID:27863252
GWAS612468_HHumanneutrophil count  IAGPrs12101888405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
734140EHD4EH domain containing 4154189593341972557Human

Position Markers

Peak: (rs12101888)
Human AssemblyChrPosition (strand)Source
GRCh381541,939,155 - 41,939,156RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
406963492GWAS612468_Hneutrophil count, eosinophil count QTL GWAS612468 (human)1e-17eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)154193915541939156Human
406957639GWAS606615_Hleukocyte count QTL GWAS606615 (human)4e-16leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)154193915541939156Human
406971639GWAS620615_Hneutrophil count QTL GWAS620615 (human)4e-17neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)154193915541939156Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
406972490GWAS621466_Hmyeloid white cell count QTL GWAS621466 (human)2e-19myeloid white cell countwhite blood cell count (CMO:0000027)154193915541939156Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS606615_H GCST004610 White blood cell count 172,435 European ancestry individuals T 0.2441 4E-16 15.398 rs12101888 0.033985 obsolete_leukocyte count (EFO:0004308)
 PMID:27863252
GWAS612468_H GCST004613 Sum neutrophil eosinophil counts 170,384 European ancestry individuals T 0.2441 1E-17 17 rs12101888 0.03573294 neutrophil count (EFO:0004833)
eosinophil count (EFO:0004842)
 PMID:27863252
GWAS620615_H GCST004629 Neutrophil count 170,702 European ancestry individuals T 0.2441 4E-17 16.398 rs12101888 0.03508634 neutrophil count (EFO:0004833)
 PMID:27863252
GWAS621466_H GCST004626 Myeloid white cell count 169,219 European ancestry individuals T 0.2441 2E-19 18.699 rs12101888 0.03781998 obsolete_myeloid white cell count (EFO:0007988)
 PMID:27863252
Database Acc Id Source(s)
GWAS Catalog GCST004613 GWAS Catalog

RGD Curation Notes
Note Type Note Reference