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Gene: PAK6 (p21 (RAC1) activated kinase 6) Homo sapiens
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Symbol: PAK6
Name: p21 (RAC1) activated kinase 6
RGD ID: 1314703
Description: Exhibits cadherin binding activity. Predicted to be involved in activation of protein kinase activity; signal transduction by protein phosphorylation; and stress-activated protein kinase signaling cascade. Localizes to cell junction; fibrillar center; and nucleoplasm. Implicated in clear cell renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: p21 protein (Cdc42/Rac)-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated kinase 6; p21-activated protein kinase 6; PAK-5; PAK-6; PAK5; serine/threonine-protein kinase PAK 6
Orthologs:
Mus musculus (house mouse) : Pak6 (p21 (RAC1) activated kinase 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pak6 (p21 (RAC1) activated kinase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak6 (p21 (RAC1) activated kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK6 (p21 (RAC1) activated kinase 6)
Canis lupus familiaris (dog) : PAK6 (p21 (RAC1) activated kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101957470 (serine/threonine-protein kinase PAK 6)
Sus scrofa (pig) : PAK6 (p21 (RAC1) activated kinase 6)
Chlorocebus sabaeus (African green monkey) : PAK6 (p21 (RAC1) activated kinase 6)
Heterocephalus glaber (naked mole-rat) : Pak6 (p21 (RAC1) activated kinase 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1540,217,428 - 40,277,487 (+)EnsemblGRCh38hg38GRCh38
GRCh381540,239,063 - 40,277,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371540,509,629 - 40,569,688 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,319,368 - 38,356,979 (+)NCBINCBI36hg18NCBI36
Build 341538,319,367 - 38,356,979NCBI
Celera1517,275,604 - 17,335,680 (+)NCBI
Cytogenetic Map15q15.1NCBI
HuRef1517,352,605 - 17,412,646 (+)NCBIHuRef
CHM1_11540,651,248 - 40,689,654 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PAK6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314703
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.