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Gene: PAK6 (p21 (RAC1) activated kinase 6) Homo sapiens
Symbol: PAK6
Name: p21 (RAC1) activated kinase 6
RGD ID: 1314703
Description: Exhibits cadherin binding activity. Predicted to be involved in activation of protein kinase activity; signal transduction by protein phosphorylation; and stress-activated protein kinase signaling cascade. Localizes to cell junction; fibrillar center; and nucleoplasm. Implicated in clear cell renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: p21 protein (Cdc42/Rac)-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated kinase 6; p21-activated protein kinase 6; PAK-5; PAK-6; PAK5; serine/threonine-protein kinase PAK 6
Mus musculus (house mouse) : Pak6 (p21 (RAC1) activated kinase 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pak6 (p21 (RAC1) activated kinase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak6 (p21 (RAC1) activated kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK6 (p21 (RAC1) activated kinase 6)
Canis lupus familiaris (dog) : PAK6 (p21 (RAC1) activated kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101957470 (serine/threonine-protein kinase PAK 6)
Sus scrofa (pig) : PAK6 (p21 (RAC1) activated kinase 6)
Chlorocebus sabaeus (African green monkey) : PAK6 (p21 (RAC1) activated kinase 6)
Heterocephalus glaber (naked mole-rat) : Pak6 (p21 (RAC1) activated kinase 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1540,217,428 - 40,277,487 (+)EnsemblGRCh38hg38GRCh38
GRCh381540,239,063 - 40,277,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371540,509,629 - 40,569,688 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,319,368 - 38,356,979 (+)NCBINCBI36hg18NCBI36
Build 341538,319,367 - 38,356,979NCBI
Celera1517,275,604 - 17,335,680 (+)NCBI
Cytogenetic Map15q15.1NCBI
HuRef1517,352,605 - 17,412,646 (+)NCBIHuRef
CHM1_11540,651,248 - 40,689,654 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PAK6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314703
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.