GWAS1132162_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1132162_H (triglyceride measurement QTL GWAS1132162 (human)) Homo sapiens

Symbol: GWAS1132162_H
Name: triglyceride measurement QTL GWAS1132162 (human)
RGD ID: 597036088
Trait: triglyceride measurement
Measurement Type: blood triglyceride level   (CMO:0000118)    
LOD Score: Not Available
P Value: 5.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381540,104,990 - 40,104,991RGD_MAPPER_PIPELINEGRCh38
GRCh371540,397,191 - 40,397,192RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1132162_HHumanblood triglyceride level  IAGPrs34245505405850206 GWAS_CATALOGPMID:32203549

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1132162_HHumantriglyceride measurement  IAGPrs34245505405850206 GWAS_CATALOGPMID:32203549

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1342866BMFBcl2 modifying factor154008789040108879Human
329343660LOC129663550ReSE screen-validated silencer GRCh37_chr15:40397101-40397293154010490040105092Human


Peak: (rs34245505)
Human AssemblyChrPosition (strand)Source
GRCh381540,104,990 - 40,104,991RGD_MAPPER_PIPELINE


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
597346366GWAS1442440_HFEV/FVC ratio QTL GWAS1442440 (human)1e-15FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)154010499040104991Human
407054315GWAS703291_Hvital capacity QTL GWAS703291 (human)2e-12vital capacity154010499040104991Human
597060543GWAS1156617_HFEV/FVC ratio QTL GWAS1156617 (human)5e-19FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)154010499040104991Human
597302992GWAS1399066_HBMI-adjusted hip circumference QTL GWAS1399066 (human)4e-11BMI-adjusted hip circumferencehip circumference (CMO:0000014)154010499040104991Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
597321591GWAS1417665_Htriglyceride measurement QTL GWAS1417665 (human)6e-10triglyceride measurementblood triglyceride level (CMO:0000118)154010499040104991Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
597036088GWAS1132162_Htriglyceride measurement QTL GWAS1132162 (human)5e-10triglyceride measurementblood triglyceride level (CMO:0000118)154010499040104991Human

1 to 10 of 18 rows


1 to 10 of 10 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1132162_H GCST010244 Triglyceride levels 441,016 European ancestry individuals C 0.804729 5E-10 9.302 rs34245505 0.015807 triglyceride measurement (EFO:0004530)
 PMID:32203549
GWAS1156617_H GCST007080 Lung function (FEV1/FVC) approximately 370,000 European ancestry individuals ? NR 5E-19 18.302 rs34245505 N/A FEV/FVC ratio (EFO:0004713)
 PMID:30595370
GWAS1661957_H GCST90492734 Type 2 diabetes 50,251 African American cases, 103,909 African American controls, 88,109 East Asian ancestry cases, 339,395 East Asian ancestry controls, 242,283 European ancestry cases, 1,569,734 European ancestry controls, 29,375 Hispanic cases, 59,368 Hispanic controls, 1,602 South African ancestry cases, 976 South African ancestry controls, 16,832 South Asian ancestry cases, 33,767 South Asian ancestry controls G 0.16393 3E-20 19.523 rs34245505 N/A PMID:38374256
GWAS703291_H GCST007429 Lung function (FVC) 321,047 European ancestry individuals C 0.805 2E-12 11.699 rs34245505 0.0212 vital capacity (EFO:0004312)
 PMID:30804560
GWAS753284_H GCST007431 Lung function (FEV1/FVC) 321,047 European ancestry individuals C 0.805 7E-13 12.155 rs34245505 0.0218 FEV/FVC ratio (EFO:0004713)
 PMID:30804560
GWAS1318735_H GCST90019498 Aspartate aminotransferase to alanine aminotransferase ratio 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals G NR 2E-9 8.699 rs34245505 0.0183 aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934)
 PMID:33462484
GWAS1361584_H GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals G 0.187902 1E-11 11 rs34245505 0.0153228 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS1399066_H GCST90020028 Hip circumference adjusted for BMI 219,872 British ancestry women G NR 4E-11 10.398 rs34245505 0.0236647 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
GWAS1417665_H GCST90244680 Triglyceride levels in non-type 2 diabetes 402,944 European ancestry individuals ? NR 6E-10 9.222 rs34245505 N/A triglyceride measurement (EFO:0004530)
 PMID:36269708
GWAS1442440_H GCST90244094 Lung function (FEV1/FVC) 475,645 European ancestry individuals, 8,590 African ancestry individuals, 85,279 East Asian ancestry individuals, 4,270 South Asian ancestry individuals, 14,668 Hispanic or Latin American individuals C 0.816 1E-15 15 rs34245505 8.018 FEV/FVC ratio (EFO:0004713)
 PMID:36914875
1 to 10 of 10 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST010244 GWAS Catalog

Note Type Note Reference