GWAS1359795_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1359795_H (free cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS1359795 (human)) Homo sapiens

Symbol: GWAS1359795_H
Name: free cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS1359795 (human)
RGD ID: 597263721
Trait: free cholesterol measurement, high density lipoprotein cholesterol measurement
Measurement Type: blood cholesterol level   (CMO:0002280)    
blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 5.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,720,123 - 58,720,124RGD_MAPPER_PIPELINEGRCh38
GRCh371559,012,322 - 59,012,323RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1359795_HHumanblood cholesterol level  IAGPrs4775090405850206 GWAS_CATALOGPMID:35213538
GWAS1359795_HHumanblood high density lipoprotein cholesterol level  IAGPrs4775090405850206 GWAS_CATALOGPMID:35213538

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1359795_HHumanfree cholesterol measurement  IAGPrs4775090405850206 GWAS_CATALOGPMID:35213538
GWAS1359795_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs4775090405850206 GWAS_CATALOGPMID:35213538

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
735847ADAM10ADAM metallopeptidase domain 10155858880958749707Human


Peak: (rs4775090)
Human AssemblyChrPosition (strand)Source
GRCh381558,720,123 - 58,720,124RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597263721GWAS1359795_Hfree cholesterol measurement, high density lipoprotein cholesterol measurement QTL GWAS1359795 (human)5e-12free cholesterol measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155872012358720124Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1359795_H GCST90093008 Free cholesterol levels in very large HDL 115,082 European ancestry individuals G 0.950527 5E-12 11.302 rs4775090 0.0620831 free cholesterol measurement (EFO:0008591)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS1757294_H GCST90093002 Average diameter for VLDL particles 115,082 European ancestry individuals G 0.950527 3E-8 7.523 rs4775090 0.0501013 VLDL particle size (OBA:2050114)
 PMID:35213538
GWAS1760068_H GCST90092869 Cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.950535 2E-8 7.699 rs4775090 0.0532702 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1778454_H GCST90092871 Cholesteryl esters to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.950535 8E-9 8.097 rs4775090 0.053245 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1778635_H GCST90092879 Triglycerides to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.950535 2E-9 8.699 rs4775090 0.0572773 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
Database
Acc Id
Source(s)
GWAS Catalog GCST90093008 GWAS Catalog

Note Type Note Reference