GWAS769100_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS769100_H (eosinophil count QTL GWAS769100 (human)) Homo sapiens

Symbol: GWAS769100_H
Name: eosinophil count QTL GWAS769100 (human)
RGD ID: 407120124
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count   (CMO:0000033)    
LOD Score: Not Available
P Value: 4.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381543,410,766 - 43,410,767RGD_MAPPER_PIPELINEGRCh38
GRCh371543,702,964 - 43,702,965RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS769100_HHumanblood eosinophil count  IAGPrs34212866405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS769100_HHumaneosinophil quantity  IAGPrs34212866405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS769100_HHumaneosinophil count  IAGPrs34212866405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1317577TP53BP1tumor protein p53 binding protein 1154340306143510640Human


Peak: (rs34212866)
Human AssemblyChrPosition (strand)Source
GRCh381543,410,766 - 43,410,767RGD_MAPPER_PIPELINE


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
597057439GWAS1153513_Heosinophil count QTL GWAS1153513 (human)6e-17eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)154341076643410767Human
597282771GWAS1378845_Heosinophil count QTL GWAS1378845 (human)1e-11eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)154341076643410767Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
597052155GWAS1148229_Heosinophil count QTL GWAS1148229 (human)1e-14eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)154341076643410767Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
597055044GWAS1151118_Heosinophil count QTL GWAS1151118 (human)2e-16eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)154341076643410767Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human

1 to 10 of 13 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS769100_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 4E-13 12.398 rs34212866 N/A eosinophil count (EFO:0004842)
 PMID:30595370
GWAS1148229_H GCST90002302 Eosinophil counts 583,850 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals G 0.219054 1E-14 14 rs34212866 N/A eosinophil count (EFO:0004842)
 PMID:32888493
GWAS1151118_H GCST90002381 Eosinophil counts 408,112 British individuals G 0.22122 2E-16 15.699 rs34212866 0.021990025 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS1153513_H GCST90002298 Eosinophil counts 474,237 European ancestry individuals G 0.220743 6E-17 16.222 rs34212866 0.020115 eosinophil count (EFO:0004842)
 PMID:32888493
GWAS1378845_H GCST90018953 Eosinophil counts 349,856 European ancestry individuals, 93,063 East Asian ancestry individuals G NR 1E-11 11 rs34212866 0.0144 eosinophil count (EFO:0004842)
 PMID:34594039
Database
Acc Id
Source(s)
GWAS Catalog GCST007065 GWAS Catalog

Note Type Note Reference