GWAS1531587_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1531587_H (high density lipoprotein cholesterol measurement QTL GWAS1531587 (human)) Homo sapiens

Symbol: GWAS1531587_H
Name: high density lipoprotein cholesterol measurement QTL GWAS1531587 (human)
RGD ID: 597435513
Trait: high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 2E-102
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,382,496 - 58,382,497RGD_MAPPER_PIPELINEGRCh38
GRCh371558,674,695 - 58,674,696RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1531587_HHumanblood high density lipoprotein cholesterol level  IAGPrs4775041405850206 GWAS_CATALOGPMID:29507422

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1531587_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs4775041405850206 GWAS_CATALOGPMID:29507422

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs4775041)
Human AssemblyChrPosition (strand)Source
GRCh381558,382,496 - 58,382,497RGD_MAPPER_PIPELINE


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597404575GWAS1500649_Hhigh density lipoprotein cholesterol measurement QTL GWAS1500649 (human)1e-11phosphatidylethanolamine measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838249658382497Human
597389983GWAS1486057_Hserum metabolite measurement QTL GWAS1486057 (human)3e-30serum metabolite measurement155838249658382497Human
597428624GWAS1524698_Hphosphatidylethanolamine measurement QTL GWAS1524698 (human)6e-16phosphatidylethanolamine measurement155838249658382497Human
597390999GWAS1487073_Hserum metabolite measurement QTL GWAS1487073 (human)2e-11serum metabolite measurement155838249658382497Human
597389975GWAS1486049_Hserum metabolite measurement QTL GWAS1486049 (human)1e-29serum metabolite measurement155838249658382497Human
596952967GWAS1072486_Hserum metabolite measurement QTL GWAS1072486 (human)2e-12serum metabolite measurement155838249658382497Human
597428367GWAS1524441_Hphosphatidylcholine measurement QTL GWAS1524441 (human)5e-39phosphatidylcholine measurement155838249658382497Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
597416974GWAS1513048_Hlysophosphatidylethanolamine measurement QTL GWAS1513048 (human)2e-16lysophosphatidylethanolamine measurement155838249658382497Human
597427721GWAS1523795_Hphosphatidylcholine measurement QTL GWAS1523795 (human)1e-69phosphatidylcholine measurement155838249658382497Human

1 to 10 of 51 rows


1 to 20 of 59 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1531587_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 2E-102 101.699 rs4775041 0.082 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS1113071_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.707 3E-22 21.523 rs4775041 0.049 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113072_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 1E-25 25 rs4775041 0.049 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1474986_H GCST000274 Metabolite levels 284 European ancestry male individuals ? 0.28 1E-7 7 rs4775041 N/A phospholipid measurement (EFO:0004639)
 PMID:19043545
GWAS1474992_H GCST000135 HDL cholesterol 8,656 European ancestry individuals C 0.33 3E-20 19.523 rs4775041 1.38 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:18193043
GWAS1474996_H GCST000139 Triglycerides 8,684 European ancestry individuals C 0.33 2E-8 7.699 rs4775041 3.62 triglyceride measurement (EFO:0004530)
 PMID:18193043
GWAS1484800_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.707 1E-13 13 rs4775041 0.034 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1484801_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 7E-16 15.155 rs4775041 0.034 triglyceride measurement (EFO:0004530)
 PMID:29507422
None Available GCST009241 Change in serum metabolite levels 3,351 Finnish ancestry men ? NR 1E-7 7 rs4775041 0.09163728 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1486049_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 1E-29 29 rs4775041 0.11236243 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1486057_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 3E-30 29.523 rs4775041 0.10351104 serum metabolite measurement (EFO:0005653)
 PMID:31636271
None Available GCST009661 Low HDL-cholesterol levels 7,423 Korean ancestry cases and controls ? 0.783 2E-8 7.699 rs4775041 1.3947002 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31910446
GWAS1486725_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 1E-26 26 rs4775041 0.09398631 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487008_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 3E-8 7.523 rs4775041 0.06805527 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487031_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 2E-12 11.699 rs4775041 0.08749205 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487073_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-11 10.699 rs4775041 0.055889677 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487373_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 4E-10 9.398 rs4775041 0.07839642 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487386_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-24 23.699 rs4775041 0.08065216 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487692_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 4E-8 7.398 rs4775041 0.06606154 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1488067_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-10 9.699 rs4775041 0.07392197 serum metabolite measurement (EFO:0005653)
 PMID:31636271
1 to 20 of 59 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST007140 GWAS Catalog

Note Type Note Reference