GWAS1113076_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1113076_H (total cholesterol measurement QTL GWAS1113076 (human)) Homo sapiens

Symbol: GWAS1113076_H
Name: total cholesterol measurement QTL GWAS1113076 (human)
RGD ID: 597017002
Trait: total cholesterol measurement
Measurement Type: blood total cholesterol level   (CMO:0000051)    
LOD Score: Not Available
P Value: 3.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,387,469 - 58,387,470RGD_MAPPER_PIPELINEGRCh38
GRCh371558,679,668 - 58,679,669RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1113076_HHumanblood total cholesterol level  IAGPrs7350789405850206 GWAS_CATALOGPMID:29507422

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1113076_HHumantotal cholesterol measurement  IAGPrs7350789405850206 GWAS_CATALOGPMID:29507422

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs7350789)
Human AssemblyChrPosition (strand)Source
GRCh381558,387,469 - 58,387,470RGD_MAPPER_PIPELINE


1 to 10 of 52 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597391002GWAS1487076_Hserum metabolite measurement QTL GWAS1487076 (human)1e-27serum metabolite measurement155838746958387470Human
597392925GWAS1488999_Hserum metabolite measurement QTL GWAS1488999 (human)2e-85serum metabolite measurement155838746958387470Human
597365532GWAS1461606_Hhematocrit QTL GWAS1461606 (human)1e-13hematocrithematocrit (CMO:0000037)155838746958387470Human
597393564GWAS1489638_Hserum metabolite measurement QTL GWAS1489638 (human)2e-11serum metabolite measurement155838746958387470Human
597393558GWAS1489632_Hserum metabolite measurement QTL GWAS1489632 (human)5e-11serum metabolite measurement155838746958387470Human
597465742GWAS1561816_Hphosphatidylethanolamine measurement QTL GWAS1561816 (human)4e-20phosphatidylethanolamine measurement155838746958387470Human
597529865GWAS1625939_H1-linoleoyl-GPE (18:2) measurement QTL GWAS1625939 (human)5e-181-linoleoyl-GPE (18:2) measurement155838746958387470Human
597383823GWAS1479897_Htriglyceride measurement QTL GWAS1479897 (human)5e-08triglyceride measurementblood triglyceride level (CMO:0000118)155838746958387470Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
597509256GWAS1605330_Hlevel of Sphingomyelin (d34:1) in blood serum QTL GWAS1605330 (human)7e-11level of Sphingomyelin (d34:1) in blood serum155838746958387470Human

1 to 10 of 52 rows


1 to 20 of 50 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1113076_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.64 3E-7 6.523 rs7350789 0.085 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113075_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.654 4E-22 21.398 rs7350789 0.047 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113077_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 2E-28 27.699 rs7350789 0.049 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1461606_H GCST90002383 Hematocrit 408,112 British individuals A 0.354791 1E-13 13 rs7350789 0.017170137 hematocrit (EFO:0004348)
 PMID:32888494
GWAS1778354_H GCST90092873 Free cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.646053 5E-99 98.302 rs7350789 0.0904029 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1778993_H GCST90092877 Phospholipids to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.646053 2E-192 191.699 rs7350789 0.124104 phospholipids:total lipids ratio (EFO:0020946)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1479897_H GCST011050 Postprandial triglyceride response 5,630 individuals A 0.36 5E-8 7.302 rs7350789 0.11 triglyceride measurement (EFO:0004530)
 PMID:32603185
GWAS1779646_H GCST90092879 Triglycerides to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.646053 1E-248 248 rs7350789 0.144797 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1484804_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.654 4E-13 12.398 rs7350789 0.032 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1484805_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.64 0.000003 5.523 rs7350789 0.071 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1484806_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 2E-18 17.699 rs7350789 0.035 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1486403_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 1E-25 25 rs7350789 0.11972121 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1486720_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 1E-12 12 rs7350789 0.08727236 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1486721_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 7E-32 31.155 rs7350789 0.10872544 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487033_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 3E-12 11.523 rs7350789 0.08568997 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487076_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 1E-27 27 rs7350789 0.08421296 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487385_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 6E-28 27.222 rs7350789 0.09362299 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487388_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 4E-30 29.398 rs7350789 0.09544789 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487725_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-14 13.699 rs7350789 0.0702734 serum metabolite measurement (EFO:0005653)
 PMID:31636271
GWAS1487727_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 8E-35 34.097 rs7350789 0.10312867 serum metabolite measurement (EFO:0005653)
 PMID:31636271
1 to 20 of 50 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST007143 GWAS Catalog

Note Type Note Reference