GWAS1644936_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1644936_H (type 2 diabetes mellitus QTL GWAS1644936 (human)) Homo sapiens

Symbol: GWAS1644936_H
Name: type 2 diabetes mellitus QTL GWAS1644936 (human)
RGD ID: 597588076
Trait: type 2 diabetes mellitus
LOD Score: Not Available
P Value: 3.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381552,296,525 - 52,296,526RGD_MAPPER_PIPELINEGRCh38
GRCh371552,588,722 - 52,588,723RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1644936_HHumantype 2 diabetes mellitus  IAGPrs74804697405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:39024449


#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
38615173LOC105370819uncharacterized LOC105370819155229488452304500Human


Peak: (rs74804697)
Human AssemblyChrPosition (strand)Source
GRCh381552,296,525 - 52,296,526RGD_MAPPER_PIPELINE


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
597588076GWAS1644936_Htype 2 diabetes mellitus QTL GWAS1644936 (human)3e-16type 2 diabetes mellitus155229652552296526Human
597594620GWAS1651480_Hglucose measurement QTL GWAS1651480 (human)2e-29glucose measurementblood glucose level (CMO:0000046)155229652552296526Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
597593928GWAS1650788_Hglucose measurement QTL GWAS1650788 (human)2e-23glucose measurementblood glucose level (CMO:0000046)155229652552296526Human
597588118GWAS1644978_Hglucose measurement QTL GWAS1644978 (human)4e-11glucose measurementblood glucose level (CMO:0000046)155229652552296526Human
597085068GWAS1181142_Htype 2 diabetes mellitus QTL GWAS1181142 (human)5e-12type 2 diabetes mellitus155229652552296526Human
597598613GWAS1655473_HHbA1c measurement QTL GWAS1655473 (human)5e-12type 2 diabetes mellitusblood hemoglobin A1c level (CMO:0002786)155229652552296526Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human

1 to 10 of 12 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1644936_H GCST90475667 Type 2 diabetes (PheCode 250.2) 154,194 European ancestry cases, 278,454 European ancestry controls C 0.9654 3E-16 15.523 rs74804697 0.082 PMID:39024449
GWAS1636636_H GCST90475658 Diabetes mellitus (PheCode 250) 154,958 European ancestry cases, 276,347 European ancestry controls C 0.9654 2E-16 15.699 rs74804697 0.0826 diabetes mellitus (EFO:0000400)
 PMID:39024449
GWAS1644978_H GCST90479625 Glucose (fasting status unknown, maximum, inv-norm transformed) 117,850 African American or Afro-Caribbean individuals, 57,272 Hispanic or Latin American individuals, 6,318 East Asian ancestry individuals, 419,671 European ancestry individuals C 0.9731 4E-11 10.398 rs74804697 0.05944 glucose measurement (EFO:0004468)
 PMID:39024449
GWAS1645581_H GCST90479626 Glucose (fasting status unknown, mean, inv-norm transformed) 118,233 African American or Afro-Caribbean individuals, 57,284 Hispanic or Latin American individuals, 6,317 East Asian ancestry individuals, 419,946 European ancestry individuals C 0.9731 7E-14 13.155 rs74804697 0.07049 glucose measurement (EFO:0004468)
 PMID:39024449
GWAS1650788_H GCST90475329 Glucose (fasting status unknown, maximum, inv-norm transformed) 419,671 European ancestry individuals C 0.9653 2E-23 22.699 rs74804697 0.06987 glucose measurement (EFO:0004468)
 PMID:39024449
GWAS1651480_H GCST90475332 Glucose (fasting status unknown, mean, inv-norm transformed) 419,946 European ancestry individuals C 0.9653 2E-29 28.699 rs74804697 0.08076 glucose measurement (EFO:0004468)
 PMID:39024449
GWAS1655473_H GCST90479501 Hemoglobin A1c (HbA1c, mean, inv-norm transformed) 98,735 African American or Afro-Caribbean individuals, 49,225 Hispanic or Latin American individuals, 5,475 East Asian ancestry individuals, 338,848 European ancestry individuals C 0.9734 5E-12 11.302 rs74804697 0.07434 HbA1c measurement (EFO:0004541)
 PMID:39024449
GWAS1181142_H GCST010555 Type 2 diabetes 148,726 European ancestry cases, 965,732 European ancestry controls G 0.0434 5E-12 11.302 rs74804697 0.0837 PMID:32541925
Database
Acc Id
Source(s)
GWAS Catalog GCST90475667 GWAS Catalog

Note Type Note Reference