GWAS1149519_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1149519_H (asthma QTL GWAS1149519 (human)) Homo sapiens

Symbol: GWAS1149519_H
Name: asthma QTL GWAS1149519 (human)
RGD ID: 597053445
Trait: asthma
LOD Score: Not Available
P Value: 7.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381560,777,789 - 60,777,790RGD_MAPPER_PIPELINEGRCh38
GRCh371561,069,988 - 61,069,989RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1149519_HHumanasthma  IAGPrs11071559405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:31361310


#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1318175RORARAR related orphan receptor A156048828461229302Human


Peak: (rs11071559)
Human AssemblyChrPosition (strand)Source
GRCh381560,777,789 - 60,777,790RGD_MAPPER_PIPELINE


1 to 10 of 28 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597110549GWAS1206623_HInhalant adrenergic use measurement QTL GWAS1206623 (human)2e-12Inhalant adrenergic use measurement156077778960777790Human
597086928GWAS1183002_Hallergic disease, age at onset QTL GWAS1183002 (human)5e-11allergic disease, age at onset156077778960777790Human
597216862GWAS1312936_Hchildhood onset asthma QTL GWAS1312936 (human)2e-37childhood onset asthma156077778960777790Human
407128013GWAS776989_Hasthma QTL GWAS776989 (human)0.0000001asthma156077778960777790Human
597056473GWAS1152547_Heosinophil count QTL GWAS1152547 (human)5e-14eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)156077778960777790Human
407178901GWAS827877_Hasthma, age at onset QTL GWAS827877 (human)0.0000008asthma, age at onset156077778960777790Human
597144903GWAS1240977_Hage of onset of asthma QTL GWAS1240977 (human)3e-22age of onset of asthma156077778960777790Human
597059524GWAS1155598_Hrespiratory system disease QTL GWAS1155598 (human)3e-13respiratory system disease156077778960777790Human
597087364GWAS1183438_Hallergic disease QTL GWAS1183438 (human)4e-11allergic disease156077778960777790Human
597053445GWAS1149519_Hasthma QTL GWAS1149519 (human)7e-20asthma156077778960777790Human

1 to 10 of 28 rows


1 to 20 of 24 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1149519_H GCST009720 Asthma 41,926 European ancestry cases, 239,773 European ancestry controls T 0.1281 7E-20 19.155 rs11071559 N/A PMID:31361310
GWAS1152547_H GCST90002298 Eosinophil counts 474,237 European ancestry individuals T 0.13051 5E-14 13.302 rs11071559 0.0222 eosinophil count (EFO:0004842)
 PMID:32888493
GWAS1155598_H GCST007076 Respiratory diseases approximately 459,000 European ancestry individuals ? NR 3E-13 12.523 rs11071559 N/A respiratory system disease (EFO:0000684)
 PMID:30595370
GWAS1183002_H GCST010985 Allergic disease (asthma, hay fever and/or eczema) (age of onset) 117,130 European ancestry individuals C 0.877 5E-11 10.302 rs11071559 0.042 age at onset (EFO:0004847)
 PMID:32603359
GWAS1183438_H GCST010984 Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) 477,968 European ancestry individuals C 0.877 4E-11 10.398 rs11071559 0.042 PMID:32603359
GWAS1206623_H GCST007941 Medication use (adrenergics, inhalants) 28,880 European ancestry cases, 147,565 European ancestry controls T 0.128561 2E-12 11.699 rs11071559 0.09462308 Inhalant adrenergic use measurement (EFO:0009941)
 PMID:31015401
GWAS1207350_H GCST007994 Asthma (age of onset) 37,846 British ancestry individuals C 0.872 0.000005 5.302 rs11071559 0.958 PMID:31036433
GWAS769102_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 1E-14 14 rs11071559 N/A eosinophil count (EFO:0004842)
 PMID:30595370
GWAS1240977_H GCST90255668 Age of onset of adult onset asthma 56,744 European ancestry cases, 674,014 European ancestry controls ? NR 3E-22 21.523 rs11071559 0.089541 age of onset of asthma (OBA:2001001)
 PMID:36778051
GWAS776989_H GCST000804 Asthma 10,365 cases, 16,110 controls C 0.86 1E-7 7 rs11071559 1.18 PMID:20860503
GWAS1261110_H GCST90018795 Asthma 38,369 European ancestry cases, 411,131 European ancestry controls, 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls T NR 1E-18 18 rs11071559 0.0833 PMID:34594039
GWAS1262826_H GCST90018575 Asthma 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls T 0.231406462 3E-14 13.523 rs11071559 0.12352817 PMID:34594039
GWAS827877_H GCST008838 Asthma (time to onset) 5,462 European ancestry cases, 8,424 European ancestry controls C 0.85 8E-7 6.097 rs11071559 1.16 age at onset (EFO:0004847)
 PMID:27130862
GWAS1300810_H GCST009798 Asthma 16,247 European ancestry cases, 346,486 European ancestry controls, 52,942 cases, 355,713 controls C 0.87197 2E-19 18.699 rs11071559 1.0895382 PMID:31959851
GWAS1304429_H GCST007995 Asthma (childhood onset) 9,433 British ancestry cases, 318,237 British ancestry controls C 0.872 3E-15 14.523 rs11071559 1.205 PMID:31036433
GWAS1312936_H GCST007800 Asthma (childhood onset) 13,962 European ancestry cases, 300,671 European ancestry controls ? NR 2E-37 36.699 rs11071559 1.145 PMID:30929738
GWAS1322755_H GCST007797 Asthma onset (childhood vs adult) 13,962 European ancestry childhood onset cases, 14,873 European ancestry adult onset cases C 0.868 0.000003 5.523 rs11071559 1.073 age at onset (EFO:0004847)
 PMID:30929738
GWAS1323192_H GCST007798 Asthma 40,544 European ancestry cases, 300,671 European ancestry controls C NR 4E-24 23.398 rs11071559 1.107 PMID:30929738
GWAS901922_H GCST010042 Asthma 64,538 European ancestry cases, 239,321 European ancestry controls C 0.859587 2E-27 26.699 rs11071559 1.0986217 PMID:32296059
GWAS922307_H GCST010043 Asthma 84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls C 0.86 5E-37 36.302 rs11071559 N/A PMID:32296059
1 to 20 of 24 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST009720 GWAS Catalog

Note Type Note Reference