Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | TMOD2 | Human | (+)-lariciresinol | decreases expression | EXP | | 6480464 | lariciresinol results in decreased expression of TMOD2 protein | CTD | PMID:27417256 | TMOD2 | Human | (-)-lariciresinol | decreases expression | EXP | | 6480464 | lariciresinol results in decreased expression of TMOD2 protein | CTD | PMID:27417256 | TMOD2 | Human | 1,2-dichloroethane | decreases expression | ISO | Tmod2 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TMOD2 mRNA | CTD | PMID:28960355 | TMOD2 | Human | 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | chlorcyclizine results in decreased expression of TMOD2 mRNA | CTD | PMID:21058326 | TMOD2 | Human | 17alpha-ethynylestradiol | increases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of TMOD2 mRNA | CTD | PMID:29097150 | TMOD2 | Human | 17beta-estradiol | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of TMOD2 mRNA | CTD | PMID:20068009 | TMOD2 | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmod2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMOD2 mRNA | CTD | PMID:21570461 | TMOD2 | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMOD2 mRNA | CTD | PMID:33387578 | TMOD2 | Human | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | TMOD2 | Human | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | Tmod2 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:18550172 | TMOD2 | Human | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | Tmod2 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:18550172 | TMOD2 | Human | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Tmod2 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of TMOD2 mRNA | CTD | PMID:25172293 | TMOD2 | Human | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TMOD2 mRNA | CTD | PMID:28628672 | TMOD2 | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of TMOD2 mRNA | CTD | PMID:30047161 | TMOD2 | Human | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of TMOD2 mRNA | CTD | PMID:32763439 | TMOD2 | Human | actinomycin D | increases expression | EXP | | 6480464 | Dactinomycin results in increased expression of TMOD2 mRNA | CTD | PMID:38460933 | TMOD2 | Human | actinomycin D | multiple interactions | EXP | | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of TMOD2 mRNA | CTD | PMID:38460933 | TMOD2 | Human | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of TMOD2 gene | CTD | PMID:27153756 | TMOD2 | Human | ammonium chloride | affects expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of TMOD2 mRNA | CTD | PMID:16483693 | TMOD2 | Human | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of TMOD2 mRNA | CTD | PMID:22316170 | TMOD2 | Human | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of TMOD2 promoter | CTD | PMID:27901495 | TMOD2 | Human | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of TMOD2 5' UTR | CTD | PMID:27901495 | TMOD2 | Human | benzo[a]pyrene | increases expression | ISO | Tmod2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TMOD2 mRNA | CTD | PMID:22610609 | TMOD2 | Human | benzo[b]fluoranthene | increases expression | ISO | Tmod2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of TMOD2 mRNA | CTD | PMID:26377693 | TMOD2 | Human | bisphenol A | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TMOD2 mRNA | CTD | PMID:25181051 more ... | TMOD2 | Human | bisphenol A | decreases expression | ISO | Tmod2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TMOD2 mRNA | CTD | PMID:32156529 | TMOD2 | Human | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TMOD2 mRNA | CTD | PMID:33670352 | TMOD2 | Human | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TMOD2 protein | CTD | PMID:33376534 | TMOD2 | Human | bisphenol A | increases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of TMOD2 mRNA | CTD | PMID:29097150 | TMOD2 | Human | bisphenol A | multiple interactions | EXP | | 6480464 | [ginger extract results in increased abundance of Oils more ... | CTD | PMID:27156127 more ... | TMOD2 | Human | bisphenol A | increases methylation | ISO | Tmod2 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of TMOD2 gene | CTD | PMID:28505145 | TMOD2 | Human | butyric acid | increases expression | EXP | | 6480464 | Butyric Acid results in increased expression of TMOD2 mRNA | CTD | PMID:33770205 and PMID:34581912 | TMOD2 | Human | camptothecin | increases expression | EXP | | 6480464 | Camptothecin results in increased expression of TMOD2 mRNA | CTD | PMID:38460933 | TMOD2 | Human | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TMOD2 gene] | CTD | PMID:28238834 | TMOD2 | Human | chlorpyrifos | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Chlorpyrifos results in decreased expression of TMOD2 mRNA | CTD | PMID:18668222 | TMOD2 | Human | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TMOD2 mRNA | CTD | PMID:27392435 | TMOD2 | Human | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of TMOD2 mRNA | CTD | PMID:27392435 | TMOD2 | Human | corosolic acid | increases expression | EXP | | 6480464 | corosolic acid results in increased expression of TMOD2 mRNA | CTD | PMID:37939859 | TMOD2 | Human | cyclosporin A | decreases methylation | EXP | | 6480464 | Cyclosporine results in decreased methylation of TMOD2 promoter | CTD | PMID:27989131 | TMOD2 | Human | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TMOD2 mRNA | CTD | PMID:28628672 | TMOD2 | Human | dibenz[a,h]anthracene | increases expression | ISO | Tmod2 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 | TMOD2 | Human | diuron | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Diuron results in decreased expression of TMOD2 mRNA | CTD | PMID:25152437 | TMOD2 | Human | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | TMOD2 | Human | epoxiconazole | increases expression | ISO | Tmod2 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of TMOD2 mRNA | CTD | PMID:35436446 | TMOD2 | Human | gentamycin | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of TMOD2 mRNA | CTD | PMID:33387578 | TMOD2 | Human | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TMOD2 mRNA | CTD | PMID:28628672 | TMOD2 | Human | lead(0) | affects splicing | EXP | | 6480464 | Lead affects the splicing of TMOD2 mRNA | CTD | PMID:28903495 | TMOD2 | Human | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of TMOD2 mRNA | CTD | PMID:28903495 | TMOD2 | Human | levonorgestrel | multiple interactions | EXP | | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TMOD2 mRNA | CTD | PMID:19074003 | TMOD2 | Human | lipopolysaccharide | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TMOD2 mRNA | CTD | PMID:35811015 | TMOD2 | Human | mercury dibromide | increases expression | EXP | | 6480464 | mercuric bromide results in increased expression of TMOD2 mRNA | CTD | PMID:26272509 | TMOD2 | Human | methimazole | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of TMOD2 mRNA | CTD | PMID:30047161 | TMOD2 | Human | methylisothiazolinone | decreases expression | EXP | | 6480464 | 2-methyl-4-isothiazolin-3-one results in decreased expression of TMOD2 mRNA | CTD | PMID:31629900 | TMOD2 | Human | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of TMOD2 mRNA | CTD | PMID:28001369 | TMOD2 | Human | microcystin-LR | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | cyanoginosin LR results in decreased expression of TMOD2 protein | CTD | PMID:22430071 | TMOD2 | Human | N-methyl-4-phenylpyridinium | increases expression | ISO | Tmod2 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of TMOD2 protein | CTD | PMID:26558463 | TMOD2 | Human | N-nitrosodiethylamine | multiple interactions | ISO | Tmod2 (Rattus norvegicus) | 6480464 | caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of TMOD2 mRNA] | CTD | PMID:20360939 | TMOD2 | Human | N-nitrosodiethylamine | increases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Diethylnitrosamine results in increased expression of TMOD2 mRNA | CTD | PMID:20360939 | TMOD2 | Human | nickel atom | decreases expression | EXP | | 6480464 | Nickel results in decreased expression of TMOD2 mRNA | CTD | PMID:25583101 | TMOD2 | Human | nickel sulfate | decreases expression | EXP | | 6480464 | nickel sulfate results in decreased expression of TMOD2 mRNA | CTD | PMID:22714537 | TMOD2 | Human | Nutlin-3 | multiple interactions | EXP | | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of TMOD2 mRNA | CTD | PMID:38460933 | TMOD2 | Human | ozone | multiple interactions | ISO | Tmod2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TMOD2 mRNA | CTD | PMID:34911549 | TMOD2 | Human | panobinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMOD2 mRNA | CTD | PMID:27188386 | TMOD2 | Human | panobinostat | increases expression | EXP | | 6480464 | panobinostat results in increased expression of TMOD2 mRNA | CTD | PMID:26272509 | TMOD2 | Human | paracetamol | increases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of TMOD2 mRNA | CTD | PMID:33387578 | TMOD2 | Human | phenethyl caffeate | multiple interactions | ISO | Tmod2 (Rattus norvegicus) | 6480464 | caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of TMOD2 mRNA] | CTD | PMID:20360939 | TMOD2 | Human | phenylmercury acetate | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMOD2 mRNA | CTD | PMID:27188386 | TMOD2 | Human | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of TMOD2 mRNA | CTD | PMID:22714537 | TMOD2 | Human | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TMOD2 mRNA | CTD | PMID:30047161 | TMOD2 | Human | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TMOD2 mRNA | CTD | PMID:23557933 | TMOD2 | Human | rotenone | decreases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of TMOD2 protein | CTD | PMID:35544339 | TMOD2 | Human | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | EXP | | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of TMOD2 mRNA | CTD | PMID:35811015 | TMOD2 | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | TMOD2 | Human | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TMOD2 mRNA | CTD | PMID:22714537 | TMOD2 | Human | sodium arsenite | decreases expression | ISO | Tmod2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TMOD2 mRNA | CTD | PMID:36209798 | TMOD2 | Human | sodium arsenite | affects methylation | EXP | | 6480464 | sodium arsenite affects the methylation of TMOD2 gene | CTD | PMID:28589171 | TMOD2 | Human | Soman | increases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Soman results in increased expression of TMOD2 mRNA | CTD | PMID:19281266 | TMOD2 | Human | sulforaphane | increases expression | EXP | | 6480464 | sulforaphane results in increased expression of TMOD2 mRNA | CTD | PMID:26833863 | TMOD2 | Human | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of TMOD2 mRNA | CTD | PMID:31533062 | TMOD2 | Human | testosterone undecanoate | multiple interactions | EXP | | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TMOD2 mRNA | CTD | PMID:19074003 | TMOD2 | Human | thimerosal | increases expression | EXP | | 6480464 | Thimerosal results in increased expression of TMOD2 mRNA | CTD | PMID:16870260 | TMOD2 | Human | titanium dioxide | decreases expression | ISO | Tmod2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of TMOD2 mRNA | CTD | PMID:23557971 and PMID:29264374 | TMOD2 | Human | titanium dioxide | decreases methylation | ISO | Tmod2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TMOD2 gene | CTD | PMID:35295148 | TMOD2 | Human | trichloroethene | increases expression | ISO | Tmod2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of TMOD2 mRNA | CTD | PMID:33387578 | TMOD2 | Human | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of TMOD2 mRNA | CTD | PMID:24935251 and PMID:26272509 | TMOD2 | Human | trichostatin A | affects expression | EXP | | 6480464 | trichostatin A affects the expression of TMOD2 mRNA | CTD | PMID:28542535 | TMOD2 | Human | trichostatin A | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMOD2 mRNA | CTD | PMID:27188386 | TMOD2 | Human | triptonide | increases expression | ISO | Tmod2 (Mus musculus) | 6480464 | triptonide results in increased expression of TMOD2 mRNA | CTD | PMID:33045310 | TMOD2 | Human | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of TMOD2 mRNA | CTD | PMID:25979313 | TMOD2 | Human | valproic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMOD2 mRNA | CTD | PMID:27188386 | TMOD2 | Human | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of TMOD2 mRNA | CTD | PMID:23179753 more ... | TMOD2 | Human | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of TMOD2 mRNA | CTD | PMID:18356318 | TMOD2 | Human | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of TMOD2 mRNA | CTD | PMID:18356318 | |