TMOD2 (tropomodulin 2) - Rat Genome Database

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Gene: TMOD2 (tropomodulin 2) Chlorocebus sabaeus
Analyze
Symbol: TMOD2
Name: tropomodulin 2
RGD ID: 18476293
Description: ENCODES a protein that exhibits actin binding (ortholog); tropomyosin binding (ortholog); INVOLVED IN learning or memory (ortholog); neuron-neuron synaptic transmission (ortholog); positive regulation of G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); developmental and epileptic encephalopathy 13 (ortholog); FOUND IN growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tropomodulin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12631,560,112 - 31,624,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2631,568,024 - 31,624,905 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048109,589,912 - 109,655,378 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TMOD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12631,560,112 - 31,624,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2631,568,024 - 31,624,905 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048109,589,912 - 109,655,378 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
TMOD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381551,751,597 - 51,816,363 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1551,751,597 - 51,816,363 (+)EnsemblGRCh38hg38GRCh38
GRCh371552,043,794 - 52,108,560 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361549,831,102 - 49,889,635 (+)NCBINCBI36Build 36hg18NCBI36
Build 341549,831,101 - 49,889,634NCBI
Celera1528,937,177 - 29,001,954 (+)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1528,874,266 - 28,939,046 (+)NCBIHuRef
CHM1_11552,161,794 - 52,226,629 (+)NCBICHM1_1
T2T-CHM13v2.01549,559,103 - 49,623,854 (+)NCBIT2T-CHM13v2.0
Tmod2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39975,472,903 - 75,518,620 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl975,472,903 - 75,518,607 (-)EnsemblGRCm39 Ensembl
GRCm38975,565,621 - 75,611,342 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl975,565,621 - 75,611,325 (-)EnsemblGRCm38mm10GRCm38
MGSCv37975,413,428 - 75,459,132 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36975,351,530 - 75,397,234 (-)NCBIMGSCv36mm8
Celera972,726,546 - 72,775,171 (-)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.31NCBI
Tmod2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8885,197,222 - 85,250,627 (-)NCBIGRCr8
mRatBN7.2876,316,736 - 76,366,003 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl876,325,667 - 76,365,720 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx881,833,194 - 81,859,701 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0880,098,086 - 80,124,579 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0877,932,534 - 77,959,043 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0882,505,947 - 82,547,450 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,506,934 - 82,533,689 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0882,108,631 - 82,148,859 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,392,806 - 80,419,315 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,411,859 - 80,438,369 (-)NCBI
Celera876,115,302 - 76,142,235 (-)NCBICelera
Cytogenetic Map8q24NCBI
Tmod2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554092,808,543 - 2,842,844 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554092,801,173 - 2,842,717 (-)NCBIChiLan1.0ChiLan1.0
TMOD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21640,985,905 - 41,053,274 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11545,166,348 - 45,233,756 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01530,690,641 - 30,757,960 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11549,035,929 - 49,087,467 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1549,035,929 - 49,079,570 (+)Ensemblpanpan1.1panPan2
TMOD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13017,425,216 - 17,501,484 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3017,455,987 - 17,592,580 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3017,351,455 - 17,420,147 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03017,571,419 - 17,646,819 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3017,588,331 - 17,740,756 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13017,492,670 - 17,561,539 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03017,611,072 - 17,686,398 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03017,717,590 - 17,785,938 (+)NCBIUU_Cfam_GSD_1.0
Tmod2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864095,742,038 - 95,794,177 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647113,602,732 - 13,729,228 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647113,602,769 - 13,636,258 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMOD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1119,956,588 - 120,009,372 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11119,956,583 - 120,009,372 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21133,216,996 - 133,269,777 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Tmod2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247318,583,352 - 8,605,826 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247318,575,955 - 8,612,553 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium 18 58
Low 18 20 2
Below cutoff

Sequence


RefSeq Acc Id: ENSCSAT00000009414   ⟹   ENSCSAP00000007532
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2631,568,024 - 31,624,905 (-)Ensembl
RefSeq Acc Id: XM_008016598   ⟹   XP_008014789
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12631,560,112 - 31,624,967 (-)NCBI
Vero_WHO_p1.0NW_023666048109,589,912 - 109,655,378 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008016599   ⟹   XP_008014790
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12631,567,157 - 31,624,928 (-)NCBI
Vero_WHO_p1.0NW_023666048109,589,912 - 109,655,378 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008014789 (Get FASTA)   NCBI Sequence Viewer  
  XP_008014790 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007532
  ENSCSAP00000007532.1
RefSeq Acc Id: XP_008014789   ⟸   XM_008016598
- UniProtKB: A0A0D9RFZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_008014790   ⟸   XM_008016599
- UniProtKB: A0A0D9RFZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007532   ⟸   ENSCSAT00000009414


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000011323 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000009414.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro LRR_dom_sf UniProtKB/TrEMBL
  TMOD UniProtKB/TrEMBL
KEGG Report csab:103245621 UniProtKB/TrEMBL
NCBI Gene TMOD2 ENTREZGENE
PANTHER PTHR10901 UniProtKB/TrEMBL
  PTHR10901:SF15 UniProtKB/TrEMBL
Pfam Tropomodulin UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A0A0D9RFZ3 ENTREZGENE, UniProtKB/TrEMBL