GWAS1146707_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1146707_H (Red cell distribution width QTL GWAS1146707 (human)) Homo sapiens

Symbol: GWAS1146707_H
Name: Red cell distribution width QTL GWAS1146707 (human)
RGD ID: 597050633
Trait: open-angle glaucoma
Measurement Type: red blood cell distribution width- standard deviation   (CMO:0003232)    
red blood cell distribution width-coefficient of variation   (CMO:0000041)    
LOD Score: Not Available
P Value: 8.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381556,794,001 - 56,794,002RGD_MAPPER_PIPELINEGRCh38
GRCh371557,086,199 - 57,086,200RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146707_HHumanopen-angle glaucoma  IAGPrs1647381405850206 GWAS_CATALOGPMID:29891935

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146707_HHumanOpen angle glaucoma  IAGPrs1647381405850206 GWAS_CATALOGPMID:29891935

Clinical Measurement

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146707_HHumanopen-angle glaucoma  IAGPrs1647381405850206 GWAS_CATALOGPMID:29891935
GWAS1146707_HHumanRed cell distribution width  IAGPrs1647381405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs1647381)
Human AssemblyChrPosition (strand)Source
GRCh381556,794,001 - 56,794,002RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
596955011GWAS1074530_HRed cell distribution width QTL GWAS1074530 (human)8e-09open-angle glaucoma155679400156794002Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
597050633GWAS1146707_HRed cell distribution width QTL GWAS1146707 (human)8e-09Red cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)155679400156794002Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1146707_H GCST007074 Red cell distribution width approximately 445,000 European ancestry individuals ? NR 8E-9 8.097 rs1647381 N/A Red cell distribution width (EFO:0009188)
 PMID:30595370
None Available GCST006065 Glaucoma (primary open-angle) 10,523 European ancestry cases, 203,579 European ancestry controls, 411 Hispanic cases, 4,778 Hispanic controls, 463 East Asian ancestry cases, 4,907 East Asian ancestry controls, 298 African American cases, 1,549 African American controls, 204 South Asian ancestry cases, 4,916 South Asian ancestry controls, 272 African British cases, 4,831 African British controls, 144 mixed ancestry cases, 3,427 mixed ancestry controls G NR 8E-9 8.097 rs1647381 1.1111112 open-angle glaucoma (EFO:0004190)
 PMID:29891935
Database
Acc Id
Source(s)
GWAS Catalog GCST006065 GWAS Catalog
  GCST007074 GWAS Catalog

Note Type Note Reference