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MRI contrast agent - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:MRI contrast agent
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Accession:CHEBI:37335 term browser browse the term


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4-carboxy-TEMPO term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpo myeloperoxidase multiple interactions ISO tempo carboxylic acid inhibits the reaction [MPO protein results in increased degradation of Hydrogen Peroxide] CTD PMID:34085520 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
dimethyl sulfoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1190005I06Rik RIKEN cDNA 1190005I06 gene affects expression ISO Dimethyl Sulfoxide affects the expression of C16ORF74 mRNA CTD PMID:24834073 NCBI chr 8:121,335,341...121,361,129
Ensembl chr 8:121,335,341...121,374,371
JBrowse link
G 1700008O03Rik RIKEN cDNA 1700008O03 gene affects expression ISO Dimethyl Sulfoxide affects the expression of C19ORF81 mRNA CTD PMID:24834073 NCBI chr 7:44,009,467...44,035,116
Ensembl chr 7:44,009,467...44,035,244
JBrowse link
G A2m alpha-2-macroglobulin increases expression ISO Dimethyl Sulfoxide results in increased expression of A2M mRNA CTD PMID:12883083 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A affects expression ISO Dimethyl Sulfoxide affects the expression of ABCB1 mRNA CTD PMID:12843640 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA]
CTD PMID:11682029 PMID:35366062 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of ACTC1 mRNA
Dimethyl Sulfoxide results in decreased expression of ACTC1 mRNA
CTD PMID:22105179 NCBI chr 2:113,877,763...113,883,356
Ensembl chr 2:113,877,763...113,884,029
JBrowse link
G Agrp agouti related neuropeptide affects expression ISO Dimethyl Sulfoxide affects the expression of AGRP mRNA CTD PMID:24834073 NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
increases expression
decreases expression
ISO
EXP
Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]
Dimethyl Sulfoxide results in increased expression of AHR mRNA; Dimethyl Sulfoxide results in increased expression of AHR protein
AHR protein affects the reaction [Dimethyl Sulfoxide results in increased phosphorylation of MYL2 protein]; Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]; Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR mRNA]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR protein]
Dimethyl Sulfoxide results in decreased expression of AHR mRNA
CTD PMID:16675542 PMID:22486318 PMID:33723743 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Aicda activation-induced cytidine deaminase affects expression ISO Dimethyl Sulfoxide affects the expression of AICDA mRNA CTD PMID:24834073 NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 multiple interactions
affects localization
EXP Dimethyl Sulfoxide inhibits the reaction [Acetaminophen affects the localization of AIFM1 protein]
Dimethyl Sulfoxide affects the localization of AIFM1 protein
CTD PMID:20423716 PMID:22535522 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440
JBrowse link
G Alas2 aminolevulinic acid synthase 2, erythroid increases expression EXP Dimethyl Sulfoxide results in increased expression of ALAS2 mRNA CTD PMID:21296123 NCBI chr  X:149,330,443...149,353,614
Ensembl chr  X:149,330,371...149,353,634
JBrowse link
G Alb albumin decreases expression
multiple interactions
ISO Dimethyl Sulfoxide results in decreased expression of ALB mRNA
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of ALB mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased secretion of ALB protein
Dimethyl Sulfoxide results in decreased expression of ALB mRNA; Dimethyl Sulfoxide results in decreased expression of ALB protein
CTD PMID:14757319 PMID:22105179 PMID:35366062 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression ISO Dimethyl Sulfoxide results in increased expression of ALDH1A1 mRNA CTD PMID:22193206 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Apoa1 apolipoprotein A-I increases expression
increases activity
ISO Dimethyl Sulfoxide results in increased expression of APOA1 mRNA; Dimethyl Sulfoxide results in increased expression of APOA1 protein
Dimethyl Sulfoxide results in increased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apom apolipoprotein M affects expression ISO Dimethyl Sulfoxide affects the expression of APOM mRNA CTD PMID:24834073 NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of AQP1 mRNA CTD PMID:22193206 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
JBrowse link
G Ar androgen receptor multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Androgens results in increased activity of AR protein] CTD PMID:28377212 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO
EXP
Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]
Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]
CTD PMID:16675542 PMID:33723743 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 affects expression ISO Dimethyl Sulfoxide affects the expression of ARPC4 mRNA CTD PMID:24834073 NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of ATF3 mRNA CTD PMID:22193206 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1A2 mRNA CTD PMID:22193206 NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631
JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1B1 mRNA CTD PMID:22193206 NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924
JBrowse link
G Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide increases expression ISO Dimethyl Sulfoxide results in increased expression of ATP1B3 mRNA CTD PMID:22193206 NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495
JBrowse link
G Atp5mf ATP synthase membrane subunit f affects expression ISO Dimethyl Sulfoxide affects the expression of ATP5MF mRNA CTD PMID:24834073 NCBI chr 5:145,120,514...145,128,351
Ensembl chr 5:145,120,508...145,128,872
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of AURKAIP1 mRNA CTD PMID:24834073 NCBI chr 4:155,915,709...155,917,555
Ensembl chr 4:155,915,729...155,917,587
JBrowse link
G Barhl2 BarH like homeobox 2 affects expression ISO Dimethyl Sulfoxide affects the expression of BARHL2 mRNA CTD PMID:24834073 NCBI chr 5:106,600,389...106,606,032
Ensembl chr 5:106,600,389...106,606,032
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of BAX mRNA
Dimethyl Sulfoxide results in increased expression of BAX protein
Quercetin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of BAX mRNA]
CTD PMID:17652743 PMID:36305173 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
ISO Dimethyl Sulfoxide results in decreased expression of BCL2 protein
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in decreased expression of BCL2 protein
CTD PMID:36305173 PMID:37365769 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bend6 BEN domain containing 6 affects expression ISO Dimethyl Sulfoxide affects the expression of BEND6 mRNA CTD PMID:24834073 NCBI chr 1:33,891,133...33,946,925
Ensembl chr 1:33,891,133...33,946,897
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of BTG2 mRNA CTD PMID:22193206 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 5:31,211,964...31,235,823
Ensembl chr 5:31,212,124...31,235,823
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CADM1 mRNA CTD PMID:22193206 NCBI chr 9:47,441,468...47,773,578
Ensembl chr 9:47,441,471...47,769,413
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases cleavage
ISO
EXP
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide co-treated with 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine] results in increased expression of CASP3 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of CASP3 protein; Dimethyl Sulfoxide results in decreased cleavage of and results in decreased activity of CASP3 protein
Dimethyl Sulfoxide results in decreased expression of CASP3 protein
Dimethyl Sulfoxide results in increased cleavage of CASP3 protein
CTD PMID:12370186 PMID:22535522 PMID:36305173 PMID:37365769 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA] CTD PMID:9169468 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases secretion
decreases expression
ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Dimethyl Sulfoxide results in increased secretion of CCL2 protein]
Dimethyl Sulfoxide results in decreased expression of CCL2 mRNA
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of CCL2 mRNA]
CTD PMID:10925121 PMID:14576080 PMID:15689417 PMID:17529908 PMID:21878375 More... NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 affects expression ISO Dimethyl Sulfoxide affects the expression of CCL28 mRNA CTD PMID:24834073 NCBI chr13:120,085,355...120,115,895
Ensembl chr13:120,085,355...120,115,895
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein] CTD PMID:21878375 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cd14 CD14 antigen increases expression ISO Dimethyl Sulfoxide results in increased expression of CD14 protein CTD PMID:26036281 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851
JBrowse link
G Cd38 CD38 antigen multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]] CTD PMID:15964820 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717
JBrowse link
G Cd3g CD3 antigen, gamma polypeptide affects expression ISO Dimethyl Sulfoxide affects the expression of CD3G mRNA CTD PMID:24834073 NCBI chr 9:44,880,870...44,891,729
Ensembl chr 9:44,880,870...44,891,729
JBrowse link
G Cd59b CD59b antigen multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased mutagenesis of CD59 gene] CTD PMID:12361925 PMID:15033018 NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,896,142...103,921,534
JBrowse link
G Cdc25b cell division cycle 25B decreases expression EXP Dimethyl Sulfoxide results in decreased expression of CDC25B mRNA CTD PMID:21296123 NCBI chr 2:131,028,356...131,040,431
Ensembl chr 2:131,028,869...131,040,417
JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of CDH1 mRNA
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CDH1 mRNA
CTD PMID:22193206 PMID:35366062 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of CDH2 mRNA CTD PMID:35366062 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
JBrowse link
G Ceacam19 CEA cell adhesion molecule 19 affects expression ISO Dimethyl Sulfoxide affects the expression of CEACAM19 mRNA CTD PMID:24834073 NCBI chr 7:19,609,667...19,621,915
Ensembl chr 7:19,609,667...19,621,890
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Dimethyl Sulfoxide results in increased expression of CEBPB mRNA CTD PMID:22193206 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Cfap300 cilia and flagella associated protein 300 affects expression ISO Dimethyl Sulfoxide affects the expression of CFAP300 mRNA CTD PMID:24834073 NCBI chr 9:8,021,673...8,042,876
Ensembl chr 9:8,021,673...8,042,824
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Dimethyl Sulfoxide affects the expression of CFLAR mRNA CTD PMID:24834073 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CGREF1 mRNA CTD PMID:24834073 NCBI chr 5:31,090,487...31,102,771
Ensembl chr 5:31,090,487...31,102,935
JBrowse link
G Chek2 checkpoint kinase 2 affects expression ISO Dimethyl Sulfoxide affects the expression of CHEK2 mRNA CTD PMID:24834073 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Cklf chemokine-like factor affects expression ISO Dimethyl Sulfoxide affects the expression of CKLF mRNA CTD PMID:24834073 NCBI chr 8:104,977,493...104,992,642
Ensembl chr 8:104,977,493...104,991,570
JBrowse link
G Cldn6 claudin 6 multiple interactions
decreases methylation
increases expression
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN6 mRNA]
Dimethyl Sulfoxide results in decreased methylation of CLDN6 promoter
Dimethyl Sulfoxide results in increased expression of CLDN6 mRNA
CTD PMID:18661270 NCBI chr17:23,898,345...23,901,417
Ensembl chr17:23,898,223...23,901,420
JBrowse link
G Cldn8 claudin 8 increases expression ISO Dimethyl Sulfoxide results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr16:88,357,714...88,360,071
Ensembl chr16:88,357,716...88,360,071
JBrowse link
G Cldn9 claudin 9 multiple interactions
increases expression
decreases methylation
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN9 mRNA]
Dimethyl Sulfoxide results in increased expression of CLDN9 mRNA
Dimethyl Sulfoxide results in decreased methylation of CLDN9 promoter
CTD PMID:18661270 NCBI chr17:23,901,558...23,903,000
Ensembl chr17:23,901,558...23,903,000
JBrowse link
G Cntf ciliary neurotrophic factor affects expression ISO Dimethyl Sulfoxide affects the expression of CNTF mRNA CTD PMID:24834073 NCBI chr19:12,740,892...12,742,996
Ensembl chr19:12,741,024...12,742,996
JBrowse link
G Col11a1 collagen, type XI, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL11A1 mRNA CTD PMID:22193206 NCBI chr 3:113,823,933...114,014,405
Ensembl chr 3:113,824,189...114,014,367
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein] CTD PMID:11682029 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col1a2 collagen, type I, alpha 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA] CTD PMID:35366062 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
JBrowse link
G Col4a1 collagen, type IV, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL4A1 mRNA CTD PMID:22193206 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826
JBrowse link
G Col4a5 collagen, type IV, alpha 5 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL4A5 mRNA CTD PMID:22193206 NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230
JBrowse link
G Col5a1 collagen, type V, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COL5A1 mRNA CTD PMID:22193206 NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946
JBrowse link
G Cp ceruloplasmin increases expression ISO Dimethyl Sulfoxide results in increased expression of CP mRNA CTD PMID:22193206 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
JBrowse link
G Cpm carboxypeptidase M increases expression ISO Dimethyl Sulfoxide results in increased expression of CPM mRNA CTD PMID:22193206 NCBI chr10:117,465,405...117,523,257
Ensembl chr10:117,465,405...117,523,257
JBrowse link
G Cs citrate synthase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Dimethyl Sulfoxide results in increased expression of CSF1R mRNA CTD PMID:8445950 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Cstpp1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CSTPP1 mRNA CTD PMID:24834073 NCBI chr 2:91,103,585...91,275,059
Ensembl chr 2:91,105,413...91,275,049
JBrowse link
G Cth cystathionine gamma lyase affects expression ISO Dimethyl Sulfoxide affects the expression of CTH mRNA CTD PMID:24834073 NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714
JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CTNNB1 protein CTD PMID:20091315 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cuta cutA divalent cation tolerance homolog affects expression ISO Dimethyl Sulfoxide affects the expression of CUTA mRNA CTD PMID:24834073 NCBI chr17:27,156,946...27,158,847
Ensembl chr17:27,152,793...27,158,543
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 affects expression ISO Dimethyl Sulfoxide affects the expression of CXCL14 mRNA CTD PMID:24834073 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
decreases expression
increases expression
ISO [Dimethyl Sulfoxide co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; Dimethyl Sulfoxide inhibits the reaction [Coal Ash results in increased secretion of CXCL8 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]
Dimethyl Sulfoxide results in decreased expression of CXCL8 mRNA
Dimethyl Sulfoxide results in increased expression of CXCL8 mRNA
CTD PMID:8969274 PMID:10022265 PMID:10688536 PMID:17529908 PMID:18684396 More... NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxxc4 CXXC finger 4 affects expression ISO Dimethyl Sulfoxide affects the expression of CXXC4 mRNA CTD PMID:24834073 NCBI chr 3:133,938,927...133,967,924
Ensembl chr 3:133,942,245...133,967,922
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [adrenocorticotropin zinc results in decreased expression of CYP11B2 mRNA]; Dimethyl Sulfoxide promotes the reaction [adrenocorticotropin zinc results in decreased activity of CYP11B2 protein] CTD PMID:10822027 NCBI chr15:74,722,467...74,728,080
Ensembl chr15:74,722,467...74,728,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects expression
multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP1A1 mRNA
JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of CYP1A1 protein]
Dimethyl Sulfoxide results in increased expression of CYP1A1; Dimethyl Sulfoxide results in increased expression of CYP1A1 protein
Dimethyl Sulfoxide results in increased expression of CYP1A1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP1A1 protein
Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:12147272 PMID:12843640 PMID:22486318 PMID:31096615 PMID:33723743 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of CYP1A2 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1A2 mRNA
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 protein; [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2
CTD PMID:12843640 PMID:18347083 PMID:30262279 PMID:35366062 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression
increases expression
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1B1 protein
CTD PMID:12843640 PMID:33723743 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]] CTD PMID:15964820 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP2A6 mRNA CTD PMID:12843640 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases expression
EXP
ISO
[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 protein
Dimethyl Sulfoxide results in increased expression of CYP2B6 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2B6 protein
CTD PMID:20371638 PMID:30262279 PMID:31096615 PMID:35366062 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [CYP2C6 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C19 protein CTD PMID:35366062 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 multiple interactions EXP [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA; [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr19:38,995,384...39,031,134
Ensembl chr19:38,995,463...39,031,137
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 protein CTD PMID:35366062 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]] CTD PMID:11368792 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
increases expression
increases activity
multiple interactions
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide results in increased activity of CYP2E1 protein
Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]
Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:1538706 PMID:3113478 PMID:3337723 PMID:8074729 PMID:9143349 More... NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP3A5 mRNA CTD PMID:12843640 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 increases expression ISO DMSO increases expression of Cyp7a1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cysrt1 cysteine rich tail 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CYSRT1 mRNA CTD PMID:24834073 NCBI chr 2:25,128,831...25,129,876
Ensembl chr 2:25,128,830...25,132,464
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of DDIT3 mRNA CTD PMID:22193206 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Depp1 DEPP1 autophagy regulator affects expression ISO Dimethyl Sulfoxide affects the expression of DEPP1 mRNA CTD PMID:24834073 NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755
JBrowse link
G Dffa DNA fragmentation factor, alpha subunit increases cleavage EXP Dimethyl Sulfoxide results in increased cleavage of DFFA protein CTD PMID:22535522 NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104
JBrowse link
G Dmap1 DNA methyltransferase 1-associated protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of DMAP1 mRNA CTD PMID:24834073 NCBI chr 4:117,531,878...117,539,450
Ensembl chr 4:117,531,878...117,539,470
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression ISO Dimethyl Sulfoxide results in increased expression of DNAJB5 mRNA CTD PMID:22193206 NCBI chr 4:42,949,866...42,959,425
Ensembl chr 4:42,949,814...42,959,425
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Dimethyl Sulfoxide results in increased expression of DNAJB9 mRNA CTD PMID:22193206 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of DNMT1 protein CTD PMID:17065238 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of DUSP1 mRNA CTD PMID:22193206 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Eaf2 ELL associated factor 2 affects expression ISO Dimethyl Sulfoxide affects the expression of EAF2 mRNA CTD PMID:24834073 NCBI chr16:36,613,246...36,695,275
Ensembl chr16:36,613,246...36,695,365
JBrowse link
G Edn2 endothelin 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of EDN2 mRNA CTD PMID:15619356 NCBI chr 4:120,018,403...120,024,557
Ensembl chr 4:120,018,403...120,024,557
JBrowse link
G Ednra endothelin receptor type A multiple interactions ISO [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein CTD PMID:20561571 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]
Dimethyl Sulfoxide results in increased expression of EDNRB mRNA; Dimethyl Sulfoxide results in increased expression of EDNRB protein
CTD PMID:20561571 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838
JBrowse link
G Eef1akmt1 EEF1A alpha lysine methyltransferase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of EEF1AKMT1 mRNA CTD PMID:24834073 NCBI chr14:57,787,052...57,809,039
Ensembl chr14:57,787,054...57,809,069
JBrowse link
G Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EFEMP1 mRNA CTD PMID:22193206 NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743
JBrowse link
G Egr1 early growth response 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EGR1 mRNA CTD PMID:22193206 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases phosphorylation
EXP [Mechlorethamine co-treated with Dimethyl Sulfoxide] results in increased phosphorylation of EIF4EBP1 protein; Mechlorethamine inhibits the reaction [Dimethyl Sulfoxide results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:36708981 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of EIF4G2 protein CTD PMID:18491231 NCBI chr 7:110,667,192...110,682,237
Ensembl chr 7:110,666,957...110,682,237
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of EMP1 mRNA CTD PMID:22193206 NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171
JBrowse link
G Endog endonuclease G affects localization EXP Dimethyl Sulfoxide affects the localization of ENDOG protein CTD PMID:22535522 NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of ENPP2 protein CTD PMID:22952646 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
JBrowse link
G Eppin epididymal peptidase inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of EPPIN mRNA CTD PMID:24834073 NCBI chr 2:164,430,263...164,435,491
Ensembl chr 2:164,430,263...164,435,514
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Eva1b eva-1 homolog B affects expression ISO Dimethyl Sulfoxide affects the expression of EVA1B mRNA CTD PMID:24834073 NCBI chr 4:126,039,502...126,043,668
Ensembl chr 4:126,041,537...126,043,668
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Dimethyl Sulfoxide results in increased expression of FAS protein CTD PMID:15998540 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand decreases expression ISO Dimethyl Sulfoxide results in decreased expression of FASLG mRNA CTD PMID:10925121 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fbxl21 F-box and leucine-rich repeat protein 21 affects expression ISO Dimethyl Sulfoxide affects the expression of FBXL21P mRNA CTD PMID:24834073 NCBI chr13:56,670,201...56,685,711
Ensembl chr13:56,670,285...56,685,711
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Dimethyl Sulfoxide results in increased expression of FGG mRNA; Dimethyl Sulfoxide results in increased expression of FGG protein CTD PMID:14757319 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Flnc filamin C, gamma increases expression ISO Dimethyl Sulfoxide results in increased expression of FLNC mRNA CTD PMID:22193206 NCBI chr 6:29,433,150...29,461,888
Ensembl chr 6:29,433,255...29,461,882
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:67,722,144...67,761,569
Ensembl chr  X:67,722,147...67,761,569
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO Dimethyl Sulfoxide results in increased expression of FOS mRNA CTD PMID:22193206 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of FOXA2 mRNA CTD PMID:22105179 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression ISO Dimethyl Sulfoxide affects the expression of FRS3 mRNA CTD PMID:24834073 NCBI chr17:47,998,532...48,015,211
Ensembl chr17:47,999,955...48,015,211
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GAD1 mRNA CTD PMID:17065238 NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha affects expression ISO Dimethyl Sulfoxide affects the expression of GADD45A mRNA CTD PMID:24834073 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma increases expression ISO Dimethyl Sulfoxide results in increased expression of GADD45G mRNA CTD PMID:22193206 NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Dimethyl Sulfoxide affects the expression of GAPDH mRNA CTD PMID:12843640 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Gata4 GATA binding protein 4 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of GATA4 mRNA
Dimethyl Sulfoxide results in increased expression of GATA4 mRNA
CTD PMID:22105179 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141
JBrowse link
G Gata6 GATA binding protein 6 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of GATA6 mRNA CTD PMID:22105179 NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJA1 mRNA CTD PMID:22193206 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJB1 mRNA CTD PMID:8631141 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of GJB2 mRNA CTD PMID:8631141 NCBI chr14:57,336,059...57,342,159
Ensembl chr14:57,336,057...57,342,159
JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GLT8D1 mRNA CTD PMID:24834073 NCBI chr14:30,723,137...30,733,948
Ensembl chr14:30,723,357...30,733,948
JBrowse link
G Gm32168 predicted gene, 32168 affects expression ISO Dimethyl Sulfoxide affects the expression of TSNARE1 mRNA CTD PMID:24834073 NCBI chr15:74,284,971...74,359,495 JBrowse link
G Gng3 guanine nucleotide binding protein (G protein), gamma 3 affects expression ISO Dimethyl Sulfoxide affects the expression of GNG3 mRNA CTD PMID:24834073 NCBI chr19:8,814,293...8,816,610
Ensembl chr19:8,814,297...8,816,558
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 decreases expression ISO DMSO decreases expression of Gpbar1 protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 1:74,316,269...74,318,868
Ensembl chr 1:74,317,709...74,318,783
JBrowse link
G Gpr75 G protein-coupled receptor 75 affects expression ISO Dimethyl Sulfoxide affects the expression of GPR75 mRNA CTD PMID:24834073 NCBI chr11:30,834,636...30,846,090
Ensembl chr11:30,835,358...30,843,729
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of GPT protein CTD PMID:37365769 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Grn granulin increases expression ISO Dimethyl Sulfoxide results in increased expression of GRN mRNA CTD PMID:16873554 NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874
JBrowse link
G Gsta3 glutathione S-transferase, alpha 3 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of GSTA3 mRNA CTD PMID:35750087 NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GSTK1 mRNA CTD PMID:24834073 NCBI chr 6:42,222,869...42,227,375
Ensembl chr 6:42,222,869...42,227,381
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein] CTD PMID:12370186 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of GSTM2 mRNA CTD PMID:22193206 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GSTP1 mRNA CTD PMID:35750087 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G H1f3 H1.3 linker histone, cluster member affects expression ISO Dimethyl Sulfoxide affects the expression of H1-3 mRNA CTD PMID:24834073 NCBI chr13:23,739,206...23,739,981
Ensembl chr13:23,737,436...23,744,860
JBrowse link
G H2-Ea histocompatibility 2, class II antigen E alpha decreases expression ISO Dimethyl Sulfoxide results in decreased expression of HLA-DRA mRNA CTD PMID:21878375 NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618
JBrowse link
G H2bc22 H2B clustered histone 22 affects expression ISO Dimethyl Sulfoxide affects the expression of H2BC17 mRNA CTD PMID:24834073 NCBI chr13:21,971,652...21,985,731
Ensembl chr13:21,971,631...21,973,383
JBrowse link
G H2bc6 H2B clustered histone 6 affects expression ISO Dimethyl Sulfoxide affects the expression of H2BC6 mRNA CTD PMID:24834073 NCBI chr13:23,767,653...23,805,091
Ensembl chr13:23,767,653...23,805,107
JBrowse link
G H3c10 H3 clustered histone 10 affects expression ISO Dimethyl Sulfoxide affects the expression of H3C6 mRNA CTD PMID:24834073 NCBI chr13:21,901,798...21,902,285
Ensembl chr13:21,901,829...21,902,239
JBrowse link
G H3f4 H3.4 histone, cluster member multiple interactions
decreases methylation
ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H3-4 protein]
Dimethyl Sulfoxide results in decreased methylation of H3-4 protein
CTD PMID:15964820 NCBI chr11:58,852,537...58,853,099
Ensembl chr11:58,852,599...58,853,364
JBrowse link
G H4c16 H4 histone 16 multiple interactions
increases methylation
ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4C16 protein modified form binds to TGM2 gene]; [Dimethyl Sulfoxide co-treated with Alitretinoin] results in increased methylation of H4C16 protein; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4C16 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4C16 protein]]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide results in increased methylation of H4C16 protein] CTD PMID:15964820 NCBI chr 6:136,780,991...136,781,429
Ensembl chr 6:136,778,551...136,781,413
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of HAND1 mRNA
Dimethyl Sulfoxide results in increased expression of HAND1 mRNA
CTD PMID:22105179 NCBI chr11:57,719,539...57,722,973
Ensembl chr11:57,719,531...57,723,644
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain increases expression EXP Dimethyl Sulfoxide results in increased expression of HBB mRNA CTD PMID:21296123
G Hcar1 hydrocarboxylic acid receptor 1 affects expression ISO Dimethyl Sulfoxide affects the expression of HCAR1 mRNA CTD PMID:24834073 NCBI chr 5:124,014,802...124,018,066
Ensembl chr 5:124,014,799...124,018,083
JBrowse link
G Hexim1 hexamethylene bis-acetamide inducible 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of HEXIM1 mRNA; Dimethyl Sulfoxide results in increased expression of HEXIM1 protein CTD PMID:16222702 NCBI chr11:103,007,151...103,010,551
Ensembl chr11:103,007,057...103,010,551
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression ISO Dimethyl Sulfoxide results in increased expression of HIF1A mRNA CTD PMID:22193206 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of HMOX1 protein
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]
Dimethyl Sulfoxide results in increased expression of HMOX1 mRNA
CTD PMID:15689417 PMID:22118543 PMID:22193206 PMID:26497626 PMID:36305173 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hp haptoglobin increases expression ISO Dimethyl Sulfoxide results in increased expression of HP mRNA; Dimethyl Sulfoxide results in increased expression of HP protein CTD PMID:14757319 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA CTD PMID:12883083 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536
JBrowse link
G Hras Harvey rat sarcoma virus oncogene affects expression ISO Dimethyl Sulfoxide affects the expression of HRAS mRNA CTD PMID:24834073 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Hspa1a heat shock protein 1A increases expression ISO Dimethyl Sulfoxide results in increased expression of HSPA1A mRNA CTD PMID:22193206 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein] CTD PMID:18539414 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ier2 immediate early response 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of IER2 mRNA CTD PMID:22193206 NCBI chr 8:85,387,960...85,389,481
Ensembl chr 8:85,387,960...85,389,483
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein] CTD PMID:21878375 PMID:29594315 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA] CTD PMID:21878375 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Ift81 intraflagellar transport 81 affects expression ISO Dimethyl Sulfoxide affects the expression of IFT81 mRNA CTD PMID:24834073 NCBI chr 5:122,678,328...122,752,614
Ensembl chr 5:122,688,267...122,752,581
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:21878375 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1B mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of IL1B protein
Dimethyl Sulfoxide results in decreased expression of IL1B mRNA
CTD PMID:21878375 PMID:29594315 PMID:37365769 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1r1 interleukin 1 receptor, type I decreases expression ISO Dimethyl Sulfoxide results in decreased expression of IL1R1 mRNA CTD PMID:21878375 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il23a interleukin 23, alpha subunit p19 affects expression ISO Dimethyl Sulfoxide affects the expression of IL23A mRNA CTD PMID:24834073 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased secretion of IL6 protein
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of IL6 protein; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA]
CTD PMID:9378980 PMID:10022265 PMID:15689417 PMID:21878375 PMID:24296301 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 affects expression ISO Dimethyl Sulfoxide affects the expression of IRGM mRNA CTD PMID:24834073 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO Dimethyl Sulfoxide affects the expression of ISG15 mRNA CTD PMID:24834073 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253
JBrowse link
G Itgam integrin alpha M multiple interactions
increases expression
ISO [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of ITGAM protein; Dexamethasone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of ITGAM protein]; Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAM protein] CTD PMID:7909661 PMID:15964820 PMID:16617325 PMID:22118543 PMID:26330309 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Itgax integrin alpha X multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAX protein] CTD PMID:15964820 NCBI chr 7:127,728,697...127,749,829
Ensembl chr 7:127,728,719...127,749,829
JBrowse link
G Itgb2 integrin beta 2 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGB2 protein] CTD PMID:15964820 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
JBrowse link
G Jdp2 Jun dimerization protein 2 multiple interactions EXP Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [AHR protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [JDP2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR mRNA]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of AHR protein]; JDP2 protein affects the reaction [Dimethyl Sulfoxide results in increased expression of CYP1A1 protein] CTD PMID:33723743 NCBI chr12:85,645,190...85,686,652
Ensembl chr12:85,645,801...85,686,652
JBrowse link
G Jun jun proto-oncogene increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of JUN mRNA
Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of JUN mRNA]
CTD PMID:7662713 PMID:22193206 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) increases expression ISO Dimethyl Sulfoxide results in increased expression of KLF2 mRNA CTD PMID:22193206 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) increases expression ISO Dimethyl Sulfoxide results in increased expression of KLF4 mRNA CTD PMID:22193206 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klhl41 kelch-like 41 affects expression ISO Dimethyl Sulfoxide affects the expression of KLHL41 mRNA CTD PMID:24834073 NCBI chr 2:69,500,464...69,514,583
Ensembl chr 2:69,500,464...69,514,574
JBrowse link
G Krt15 keratin 15 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of KRT15 mRNA CTD PMID:22105179 NCBI chr11:100,022,585...100,026,775
Ensembl chr11:100,022,584...100,026,754
JBrowse link
G Krt18 keratin 18 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of KRT18 mRNA CTD PMID:35366062 NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
JBrowse link
G Lama1 laminin, alpha 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of LAMA1 mRNA CTD PMID:22193206 NCBI chr17:68,004,129...68,129,640
Ensembl chr17:68,004,254...68,129,642
JBrowse link
G Lamb2 laminin, beta 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of LAMB2 mRNA CTD PMID:22193206 NCBI chr 9:108,357,080...108,367,729
Ensembl chr 9:108,356,935...108,367,729
JBrowse link
G Ldhc lactate dehydrogenase C affects expression ISO Dimethyl Sulfoxide affects the expression of LDHC mRNA CTD PMID:24834073 NCBI chr 7:46,510,687...46,527,571
Ensembl chr 7:46,510,627...46,527,566
JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 affects expression ISO Dimethyl Sulfoxide affects the expression of LGALS1 mRNA CTD PMID:24834073 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
JBrowse link
G Llgl2 LLGL2 scribble cell polarity complex component affects expression ISO Dimethyl Sulfoxide affects the expression of LLGL2 mRNA CTD PMID:24834073 NCBI chr11:115,714,855...115,746,606
Ensembl chr11:115,714,875...115,746,606
JBrowse link
G Lrrc4 leucine rich repeat containing 4 affects expression ISO Dimethyl Sulfoxide affects the expression of LRRC4 mRNA CTD PMID:24834073 NCBI chr 6:28,828,125...28,831,746
Ensembl chr 6:28,661,830...28,831,746
JBrowse link
G Lyrm9 LYR motif containing 9 affects expression ISO Dimethyl Sulfoxide affects the expression of LYRM9 mRNA CTD PMID:24834073 NCBI chr11:78,717,421...78,734,725
Ensembl chr11:78,717,410...78,737,696
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions
increases expression
ISO cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA] CTD PMID:31265865 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA]
CTD PMID:31265865 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
decreases activity
ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased activity of MAP3K5 protein]
Dimethyl Sulfoxide results in decreased activity of MAP3K5 protein
CTD PMID:12370186 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of MAPK3 mRNA
Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA]
CTD PMID:24834073 PMID:31265865 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mat1a methionine adenosyltransferase 1A increases activity EXP Dimethyl Sulfoxide results in increased activity of MAT1A protein CTD PMID:8373829 NCBI chr14:40,826,969...40,846,385
Ensembl chr14:40,826,992...40,846,369
JBrowse link
G Mat2a methionine adenosyltransferase 2A increases activity EXP Dimethyl Sulfoxide results in increased activity of MAT2A protein CTD PMID:8373829 NCBI chr 6:72,409,779...72,416,539
Ensembl chr 6:72,409,782...72,416,541
JBrowse link
G Mc1r melanocortin 1 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of MC1R mRNA CTD PMID:24834073 NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483
JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of MEF2C mRNA
Dimethyl Sulfoxide results in decreased expression of MEF2C mRNA
CTD PMID:22105179 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199
JBrowse link
G Mettl26 methyltransferase like 26 affects expression ISO Dimethyl Sulfoxide affects the expression of METTL26 mRNA CTD PMID:24834073 NCBI chr17:26,094,474...26,096,137
Ensembl chr17:26,094,048...26,096,143
JBrowse link
G Mfap5 microfibrillar associated protein 5 affects expression ISO Dimethyl Sulfoxide affects the expression of MFAP5 mRNA CTD PMID:24834073 NCBI chr 6:122,490,543...122,506,249
Ensembl chr 6:122,482,804...122,506,249
JBrowse link
G Mir320 microRNA 320 multiple interactions ISO dimethyl sulfoxide promotes the reaction [ischemia-reperfusion injury increases expression of Mir320a miRNA in nucleus] RGD PMID:31089916 RGD:155882543 NCBI chr14:70,680,950...70,681,031
Ensembl chr14:70,680,950...70,681,031
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP13 mRNA CTD PMID:35366062 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) increases expression ISO Dimethyl Sulfoxide results in increased expression of MMP1 mRNA; Dimethyl Sulfoxide results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
ISO [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]
Dimethyl Sulfoxide results in increased expression of MMP2 protein
CTD PMID:26497626 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Dimethyl Sulfoxide inhibits the reaction [Ethanol results in increased activity of MMP9 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP9 mRNA
Dimethyl Sulfoxide results in increased expression of MMP9 protein
CTD PMID:17603938 PMID:26497626 PMID:35366062 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase increases secretion
multiple interactions
increases expression
EXP
ISO
Dimethyl Sulfoxide results in increased secretion of MPO protein
[Irinotecan co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein; [Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein; GSK484 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; Irinotecan promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; phenethyl isothiocyanate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; Tetradecanoylphorbol Acetate promotes the reaction [Dimethyl Sulfoxide results in increased expression of MPO mRNA]
CTD PMID:21633126 PMID:38341106 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mrpl43 mitochondrial ribosomal protein L43 affects expression ISO Dimethyl Sulfoxide affects the expression of MRPL43 mRNA CTD PMID:24834073 NCBI chr19:44,993,584...44,994,860
Ensembl chr19:44,993,268...44,994,881
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein] CTD PMID:10640773 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Mug2 murinoglobulin 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of PZP mRNA; Dimethyl Sulfoxide results in increased expression of PZP protein CTD PMID:14757319 NCBI chr 6:121,983,688...122,062,927
Ensembl chr 6:121,983,720...122,062,924
JBrowse link
G Mxra8 matrix-remodelling associated 8 increases expression ISO Dimethyl Sulfoxide results in increased expression of MXRA8 mRNA CTD PMID:22193206 NCBI chr 4:155,924,137...155,928,559
Ensembl chr 4:155,924,137...155,928,545
JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO Dimethyl Sulfoxide results in decreased expression of MYC mRNA CTD PMID:7798212 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow multiple interactions
increases phosphorylation
EXP AHR protein affects the reaction [Dimethyl Sulfoxide results in increased phosphorylation of MYL2 protein] CTD PMID:33723743 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535
JBrowse link
G Myo1g myosin IG increases expression ISO Dimethyl Sulfoxide results in increased expression of MYO1G mRNA CTD PMID:22193206 NCBI chr11:6,456,548...6,470,960
Ensembl chr11:6,456,548...6,470,965
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NANOG mRNA CTD PMID:22105179 NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592
JBrowse link
G Nefh neurofilament, heavy polypeptide decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NEFH mRNA CTD PMID:22105179 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nes nestin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NES mRNA CTD PMID:22105179 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
increases expression
affects response to substance
decreases expression
ISO
EXP
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]
Dimethyl Sulfoxide results in increased expression of NFE2L2 protein modified form
NFE2L2 protein affects the susceptibility to Dimethyl Sulfoxide
dimethyl sulfoxide promotes the reaction [ischemia-reperfusion injury increases expression of Nfe2l2 protein in nucleus]
Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]; JDP2 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [NFE2L2 protein binds to AHR promoter]]
Dimethyl Sulfoxide results in decreased expression of NFE2L2 protein
CTD
RGD
PMID:26497626 PMID:32023790 PMID:33723743 PMID:36305173 PMID:31089916 RGD:155882543 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA] CTD PMID:21878375 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA] CTD PMID:21878375 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nmi N-myc (and STAT) interactor affects expression ISO Dimethyl Sulfoxide affects the expression of NMI mRNA CTD PMID:24834073 NCBI chr 2:51,838,517...51,863,241
Ensembl chr 2:51,838,499...51,863,506
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NMRK1 mRNA CTD PMID:24834073 NCBI chr19:18,609,380...18,629,555
Ensembl chr19:18,609,314...18,629,792
JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NOS2 mRNA CTD PMID:21878375 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Notch3 notch 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of NOTCH3 mRNA CTD PMID:20713136 NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of NQO1 mRNA CTD PMID:22193206 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO DMSO decreases expression of Nr1h4 mRNA and protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nudt1 nudix hydrolase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NUDT1 mRNA CTD PMID:24834073 NCBI chr 5:140,307,375...140,323,892
Ensembl chr 5:140,307,411...140,323,892
JBrowse link
G Ocln occludin increases expression ISO Dimethyl Sulfoxide results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of ORM1 mRNA; Dimethyl Sulfoxide results in increased expression of ORM1 protein CTD PMID:14757319 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
JBrowse link
G Ostn osteocrin affects expression ISO Dimethyl Sulfoxide affects the expression of OSTN mRNA CTD PMID:24834073 NCBI chr16:27,125,733...27,169,959
Ensembl chr16:27,126,239...27,169,962
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of P2RX7 protein CTD PMID:37365769 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Padi4 peptidyl arginine deiminase, type IV multiple interactions
increases expression
ISO Calcimycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of PADI4 protein]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of PADI4 mRNA] CTD PMID:15964820 PMID:29425503 NCBI chr 4:140,472,819...140,501,514
Ensembl chr 4:140,473,176...140,501,547
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha affects expression ISO Dimethyl Sulfoxide affects the expression of PARD6A mRNA CTD PMID:24834073 NCBI chr 8:106,427,780...106,430,126
Ensembl chr 8:106,427,780...106,430,128
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage EXP Dimethyl Sulfoxide results in increased cleavage of PARP1 protein CTD PMID:22535522 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of PDCD4 protein CTD PMID:17259349 NCBI chr19:53,880,662...53,926,024
Ensembl chr19:53,880,662...53,918,291
JBrowse link
G Phf6 PHD finger protein 6 affects expression ISO Dimethyl Sulfoxide affects the expression of PHF6 mRNA CTD PMID:24834073 NCBI chr  X:52,001,091...52,045,838
Ensembl chr  X:52,001,143...52,045,820
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing affects expression ISO Dimethyl Sulfoxide affects the expression of PIKFYVE mRNA CTD PMID:24834073 NCBI chr 1:65,225,796...65,317,855
Ensembl chr 1:65,225,842...65,317,854
JBrowse link
G Pjvk pejvakin affects expression ISO Dimethyl Sulfoxide affects the expression of PJVK mRNA CTD PMID:24834073 NCBI chr 2:76,480,617...76,488,898
Ensembl chr 2:76,478,820...76,488,900
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PLA2G2A mRNA CTD PMID:21878375 NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497
JBrowse link
G Plekhf1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PLEKHF1 mRNA CTD PMID:24834073 NCBI chr 7:37,920,078...37,927,418
Ensembl chr 7:37,916,396...37,927,440
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of PLOD2 mRNA CTD PMID:22193206 NCBI chr 9:92,421,828...92,490,481
Ensembl chr 9:92,424,276...92,490,481
JBrowse link
G Pomc pro-opiomelanocortin-alpha decreases expression EXP Dimethyl Sulfoxide results in decreased expression of POMC protein CTD PMID:15680486 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
decreases activity
EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical]
Dimethyl Sulfoxide results in decreased activity of POR protein
Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Dimethyl Sulfoxide promotes the reaction [Hemin results in decreased activity of POR protein]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide results in decreased activity of POR protein]
CTD PMID:11368792 PMID:21215309 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Pot1a protection of telomeres 1A multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; [Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA CTD PMID:26330309 NCBI chr 6:25,743,939...25,809,280
Ensembl chr 6:25,743,736...25,809,245
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 affects expression ISO Dimethyl Sulfoxide affects the expression of POU5F1 mRNA CTD PMID:24834073 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARA mRNA CTD PMID:21878375 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARG mRNA CTD PMID:21878375 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Pqbp1 polyglutamine binding protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PQBP1 mRNA CTD PMID:24834073 NCBI chr  X:7,760,759...7,765,469
Ensembl chr  X:7,760,758...7,765,508
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 multiple interactions ISO PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]] CTD PMID:31877331 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link
G Prph peripherin affects expression ISO Dimethyl Sulfoxide affects the expression of PRPH mRNA CTD PMID:24834073 NCBI chr15:98,951,452...98,956,858
Ensembl chr15:98,953,055...98,956,859
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PTGS1 mRNA CTD PMID:21878375 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Dimethyl Sulfoxide results in increased expression of PTGS2 protein
CTD PMID:21878375 PMID:26497626 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Pxdn peroxidasin increases expression ISO Dimethyl Sulfoxide results in increased expression of PXDN mRNA CTD PMID:22193206 NCBI chr12:29,986,641...30,067,657
Ensembl chr12:29,987,607...30,067,657
JBrowse link
G Rab3c RAB3C, member RAS oncogene family affects expression ISO Dimethyl Sulfoxide affects the expression of RAB3C mRNA CTD PMID:24834073 NCBI chr13:110,190,721...110,417,530
Ensembl chr13:110,190,721...110,417,530
JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of RAF1 mRNA CTD PMID:31265865 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of RELA protein CTD PMID:37365769 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Reln reelin increases expression ISO Dimethyl Sulfoxide results in increased expression of RELN mRNA CTD PMID:17065238 NCBI chr 5:22,089,452...22,549,703
Ensembl chr 5:22,089,452...22,549,700
JBrowse link
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) affects expression ISO Dimethyl Sulfoxide affects the expression of RFX3 mRNA CTD PMID:24834073 NCBI chr19:27,739,121...27,995,287
Ensembl chr19:27,739,121...27,988,566
JBrowse link
G Rnase4 ribonuclease, RNase A family 4 affects expression ISO Dimethyl Sulfoxide affects the expression of RNASE4 mRNA CTD PMID:24834073 NCBI chr14:51,328,534...51,343,608
Ensembl chr14:51,328,534...51,343,608
JBrowse link
G Rnf152 ring finger protein 152 affects expression ISO Dimethyl Sulfoxide affects the expression of RNF152 mRNA CTD PMID:24834073 NCBI chr 1:105,204,642...105,284,665
Ensembl chr 1:105,204,639...105,284,435
JBrowse link
G Rps6 ribosomal protein S6 affects phosphorylation
multiple interactions
increases phosphorylation
ISO
EXP
Dimethyl Sulfoxide affects the phosphorylation of RPS6 protein
Mechlorethamine affects the reaction [Dimethyl Sulfoxide affects the phosphorylation of RPS6 protein]
[Dimethyl Sulfoxide co-treated with Mechlorethamine] results in increased phosphorylation of RPS6 protein; Mechlorethamine inhibits the reaction [Dimethyl Sulfoxide results in increased phosphorylation of RPS6 protein]
CTD PMID:36708981 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649
JBrowse link
G Rxra retinoid X receptor alpha increases expression
affects response to substance
EXP Dimethyl Sulfoxide results in increased expression of RXRA mRNA; Dimethyl Sulfoxide results in increased expression of RXRA protein
RXRA protein affects the susceptibility to Dimethyl Sulfoxide
CTD PMID:9751115 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression EXP Dimethyl Sulfoxide results in decreased expression of RXRG protein CTD PMID:9751115 NCBI chr 1:167,425,902...167,467,191
Ensembl chr 1:167,425,953...167,467,192
JBrowse link
G S100a13 S100 calcium binding protein A13 affects expression ISO Dimethyl Sulfoxide affects the expression of S100A13 mRNA CTD PMID:24834073 NCBI chr 3:90,421,542...90,431,888
Ensembl chr 3:90,421,659...90,431,890
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A8 mRNA CTD PMID:1733233 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A9 mRNA CTD PMID:1733233 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
JBrowse link
G Sdhaf4 succinate dehydrogenase complex assembly factor 4 affects expression ISO Dimethyl Sulfoxide affects the expression of SDHAF4 mRNA CTD PMID:24834073 NCBI chr 1:24,035,020...24,044,721
Ensembl chr 1:24,035,020...24,044,737
JBrowse link
G Selenbp1 selenium binding protein 1 increases abundance ISO SELENBP1 gene mutant form results in increased abundance of Dimethyl Sulfoxide CTD PMID:29255262 NCBI chr 3:94,840,394...94,852,069
Ensembl chr 3:94,840,367...94,852,069
JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SERP2 mRNA CTD PMID:24834073 NCBI chr14:76,770,252...76,794,518
Ensembl chr14:76,770,254...76,794,329
JBrowse link
G Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of SLC24A2 mRNA CTD PMID:22193206 NCBI chr 4:86,901,361...87,148,780
Ensembl chr 4:86,901,361...87,148,714
JBrowse link
G Slc24a4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of SLC24A4 mRNA CTD PMID:22193206 NCBI chr12:102,094,986...102,239,562
Ensembl chr12:102,094,992...102,233,350
JBrowse link
G Slc2a6 solute carrier family 2 (facilitated glucose transporter), member 6 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC2A6 mRNA CTD PMID:24834073 NCBI chr 2:26,911,375...26,918,011
Ensembl chr 2:26,911,375...26,918,010
JBrowse link
G Slc35e4 solute carrier family 35, member E4 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC35E4 mRNA CTD PMID:24834073 NCBI chr11:3,857,022...3,864,664
Ensembl chr11:3,857,021...3,864,664
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD2 protein modified form CTD PMID:35366062 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD3 protein modified form CTD PMID:35366062 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Smad4 SMAD family member 4 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD4 protein CTD PMID:35366062 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851
JBrowse link
G Snai1 snail family zinc finger 1 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI1 mRNA CTD PMID:35366062 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734
JBrowse link
G Snai2 snail family zinc finger 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI2 mRNA CTD PMID:35366062 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
JBrowse link
G Snx15 sorting nexin 15 affects expression ISO Dimethyl Sulfoxide affects the expression of SNX15 mRNA CTD PMID:24834073 NCBI chr19:6,169,429...6,182,446
Ensembl chr19:6,169,429...6,178,334
JBrowse link
G Sod3 superoxide dismutase 3, extracellular increases expression ISO Dimethyl Sulfoxide results in increased expression of SOD3 mRNA CTD PMID:22193206 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of SORD protein] CTD PMID:17177172 NCBI chr 2:122,065,320...122,095,818
Ensembl chr 2:122,065,230...122,095,821
JBrowse link
G Sox17 SRY (sex determining region Y)-box 17 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of SOX17 mRNA CTD PMID:22105179 NCBI chr 1:4,561,154...4,567,624
Ensembl chr 1:4,561,154...4,567,577
JBrowse link
G Sp1 trans-acting transcription factor 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SPINK2 mRNA CTD PMID:24834073 NCBI chr 5:77,352,953...77,364,106
Ensembl chr 5:77,352,954...77,359,318
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO DMSO increases expression of Srebf1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression ISO Dimethyl Sulfoxide results in increased expression of SRXN1 mRNA CTD PMID:22193206 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 affects expression ISO Dimethyl Sulfoxide affects the expression of STAC3 mRNA CTD PMID:24834073 NCBI chr10:127,337,505...127,344,692
Ensembl chr10:127,337,555...127,344,692
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA CTD PMID:31265865 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects expression ISO Dimethyl Sulfoxide affects the expression of SUMO1 mRNA CTD PMID:24834073 NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993
JBrowse link
G Syce2 synaptonemal complex central element protein 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SYCE2 mRNA CTD PMID:24834073 NCBI chr 8:85,598,740...85,614,075
Ensembl chr 8:85,598,740...85,614,850
JBrowse link
G Tas2r140 taste receptor, type 2, member 140 affects expression ISO Dimethyl Sulfoxide affects the expression of TAS2R14 mRNA CTD PMID:24834073 NCBI chr 6:133,031,818...133,032,756
Ensembl chr 6:133,031,780...133,032,779
JBrowse link
G Tatdn1 TatD DNase domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of TATDN1 mRNA CTD PMID:24834073 NCBI chr15:58,762,002...58,805,605
Ensembl chr15:58,762,004...58,805,587
JBrowse link
G Terc telomerase RNA component multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA CTD PMID:26330309 NCBI chr 3:96,321,753...96,322,149
Ensembl chr 3:96,321,753...96,322,149
JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA CTD PMID:26330309 NCBI chr 1:15,875,634...15,914,283
Ensembl chr 1:15,875,870...15,914,276
JBrowse link
G Terf2 telomeric repeat binding factor 2 multiple interactions ISO [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dimethyl Sulfoxide co-treated with Tretinoin] results in decreased expression of TERF2 mRNA; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF2 mRNA CTD PMID:26330309 NCBI chr 8:107,796,032...107,823,180
Ensembl chr 8:107,796,032...107,823,179
JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
EXP
ISO
Dimethyl Sulfoxide results in decreased expression of TERT mRNA
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA
CTD PMID:16180984 PMID:26330309 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962
JBrowse link
G Tfpi tissue factor pathway inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of TFPI mRNA CTD PMID:24834073 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased abundance of Adenosine Triphosphate; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of ALB mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CDH1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2B6 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C19 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP2C9 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP3A4 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP3A4 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of KRT18 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP13 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of MMP9 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased secretion of ALB protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of CDH2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD2 protein modified form; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD3 protein modified form; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SMAD4 protein; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of SNAI2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP2 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of VIM mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB1 mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB2 mRNA; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA]; LY-2157299 inhibits the reaction [[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of COL1A2 mRNA] CTD PMID:35366062 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgm2 transglutaminase 2, C polypeptide multiple interactions ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4C16 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]] CTD PMID:15964820 NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP1 mRNA CTD PMID:35366062 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein]
[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of TIMP2 mRNA
CTD PMID:11682029 PMID:35366062 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein affects expression ISO Dimethyl Sulfoxide affects the expression of TIRAP mRNA CTD PMID:24834073 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tmem121 transmembrane protein 121 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM121 mRNA CTD PMID:24834073 NCBI chr12:113,149,523...113,153,143
Ensembl chr12:113,149,550...113,153,143
JBrowse link
G Tmem134 transmembrane protein 134 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM134 mRNA CTD PMID:24834073 NCBI chr19:4,175,960...4,182,306
Ensembl chr19:4,175,934...4,182,306
JBrowse link
G Tmem150c transmembrane protein 150C affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM150C mRNA CTD PMID:24834073 NCBI chr 5:100,225,731...100,313,463
Ensembl chr 5:100,225,731...100,307,667
JBrowse link
G Tmem266 transmembrane protein 266 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM266 mRNA CTD PMID:24834073 NCBI chr 9:55,234,194...55,345,629
Ensembl chr 9:55,234,197...55,345,629
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
[lipopolysaccharide, E coli O55-B5 co-treated with Dimethyl Sulfoxide] results in increased expression of TNF protein; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [ferrous sulfate promotes the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]]
Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]
CTD PMID:7539275 PMID:14576080 PMID:21878375 PMID:22319556 PMID:37365769 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a increases expression ISO Dimethyl Sulfoxide results in increased expression of TNFRSF12A mRNA CTD PMID:22193206 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] CTD PMID:9870925 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 affects expression ISO Dimethyl Sulfoxide affects the expression of TOMM5 mRNA CTD PMID:24834073 NCBI chr 4:45,105,209...45,108,113
Ensembl chr 4:45,105,208...45,108,114
JBrowse link
G Tpm3 tropomyosin 3, gamma increases expression ISO Dimethyl Sulfoxide results in increased expression of TPM3 mRNA CTD PMID:22193206 NCBI chr 3:89,979,958...90,008,209
Ensembl chr 3:89,979,956...90,008,209
JBrowse link
G Tra2b transformer 2 beta increases expression ISO Dimethyl Sulfoxide results in increased expression of TRA2B mRNA CTD PMID:22193206 NCBI chr16:22,063,302...22,084,755
Ensembl chr16:22,063,299...22,084,755
JBrowse link
G Trf transferrin increases expression ISO Dimethyl Sulfoxide results in increased expression of TF mRNA CTD PMID:22193206 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of TRIB3 mRNA CTD PMID:22193206 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 affects expression ISO Dimethyl Sulfoxide affects the expression of TSC22D3 mRNA CTD PMID:24834073 NCBI chr  X:139,440,277...139,501,257
Ensembl chr  X:139,440,277...139,501,408
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO Dimethyl Sulfoxide results in decreased expression of TUBB3 mRNA CTD PMID:22105179 NCBI chr 8:124,138,292...124,148,754
Ensembl chr 8:124,138,163...124,148,754
JBrowse link
G U2af1l4 U2 small nuclear RNA auxiliary factor 1-like 4 affects expression ISO Dimethyl Sulfoxide affects the expression of U2AF1L4 mRNA CTD PMID:24834073 NCBI chr 7:30,262,765...30,264,789
Ensembl chr 7:30,262,726...30,264,790
Ensembl chr 7:30,262,726...30,264,790
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C affects expression ISO Dimethyl Sulfoxide affects the expression of UBE2C mRNA CTD PMID:24834073 NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742
JBrowse link
G Ufsp1 UFM1-specific peptidase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of UFSP1 mRNA CTD PMID:24834073 NCBI chr 5:137,292,931...137,293,926
Ensembl chr 5:137,292,891...137,293,927
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A6 mRNA CTD PMID:12843640 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A9 mRNA CTD PMID:12843640 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Upk3b uroplakin 3B affects expression ISO Dimethyl Sulfoxide affects the expression of UPK3B mRNA CTD PMID:24834073 NCBI chr 5:136,067,350...136,073,847
Ensembl chr 5:136,067,350...136,075,341
JBrowse link
G Uts2r urotensin 2 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of UTS2R mRNA CTD PMID:24834073 NCBI chr11:121,051,097...121,052,799
Ensembl chr11:121,051,097...121,052,799
JBrowse link
G Vim vimentin multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of VIM mRNA CTD PMID:35366062 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Vmn1r224 vomeronasal 1 receptor 224 affects expression ISO Dimethyl Sulfoxide affects the expression of VN1R2 mRNA CTD PMID:24834073 NCBI chr17:20,639,425...20,640,321
Ensembl chr17:20,634,408...20,645,605
JBrowse link
G Wapl WAPL cohesin release factor increases expression ISO Dimethyl Sulfoxide results in increased expression of WAPL mRNA CTD PMID:15797623 NCBI chr14:34,394,086...34,469,940
Ensembl chr14:34,395,885...34,469,940
JBrowse link
G Wnt11 wingless-type MMTV integration site family, member 11 affects expression ISO Dimethyl Sulfoxide affects the expression of WNT11 mRNA CTD PMID:24834073 NCBI chr 7:98,484,293...98,503,954
Ensembl chr 7:98,484,319...98,504,402
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB1 mRNA CTD PMID:35366062 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in increased expression of ZEB2 mRNA CTD PMID:35366062 NCBI chr 2:44,873,523...45,007,378
Ensembl chr 2:44,873,644...45,007,407
JBrowse link
G Zfp36 zinc finger protein 36 affects expression ISO Dimethyl Sulfoxide affects the expression of ZFP36 mRNA CTD PMID:24834073 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678
JBrowse link
ferric ammonium citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
decreases activity
EXP ferric ammonium citrate results in increased activity of ACO1 protein
ferric ammonium citrate results in decreased activity of ACO1 protein
CTD PMID:11054110 PMID:18073202 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338
JBrowse link
G Aco2 aconitase 2, mitochondrial multiple interactions
increases activity
ISO ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]; ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein]
ferric ammonium citrate results in increased activity of ACO2 protein
CTD PMID:16625280 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
multiple interactions
ISO
EXP
ferric ammonium citrate results in increased expression of ACP5 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Niacin inhibits the reaction [ferric ammonium citrate results in increased expression of ACP5 protein]]; Niacin inhibits the reaction [ferric ammonium citrate results in increased expression of ACP5 protein]
Silybin inhibits the reaction [ferric ammonium citrate results in increased expression of ACP5 protein]
CTD PMID:36087815 PMID:38081572 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] CTD PMID:32283200 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Alb albumin multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of ALB protein] CTD PMID:24862973 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions EXP ferric ammonium citrate results in decreased expression of and results in decreased activity of ALPL protein; Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of and results in decreased activity of ALPL protein] CTD PMID:36087815 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
JBrowse link
G Anxa3 annexin A3 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein] CTD PMID:19515424 NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein] CTD PMID:19515424 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of BECN1 protein; [Hydrogen Peroxide co-treated with [ferric ammonium citrate results in increased abundance of Iron]] results in increased expression of BECN1 protein; BECN1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]; BECN1 protein affects the reaction [Hydrogen Peroxide inhibits the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]] CTD PMID:34826546 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO
EXP
ferric ammonium citrate results in increased cleavage of CASP3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:17191120 PMID:26318285 PMID:27481217 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
ISO ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein]
ferric ammonium citrate results in increased expression of CDKN1A protein
CTD PMID:12807743 PMID:38483099 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression ISO ferric ammonium citrate results in increased expression of CDKN2A protein CTD PMID:38483099 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Col1a1 collagen, type I, alpha 1 decreases expression EXP ferric ammonium citrate results in decreased expression of COL1A1 mRNA CTD PMID:19735707 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
increases secretion
ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of CXCL8 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of CXCL8 protein]
ferric ammonium citrate results in increased secretion of CXCL8 protein
CTD PMID:10688536 PMID:24862973 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases phosphorylation
EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Cyclosporine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; ferric ammonium citrate results in decreased phosphorylation of and affects the localization of DNM1L protein; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:26318285 PMID:27481217 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Erp29 endoplasmic reticulum protein 29 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein] CTD PMID:19515424 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569
JBrowse link
G F3 coagulation factor III increases expression
multiple interactions
ISO ferric ammonium citrate results in increased expression of F3 mRNA
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA]
CTD PMID:25858758 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Fth1 ferritin heavy polypeptide 1 multiple interactions
increases expression
ISO ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein]
ferric ammonium citrate results in increased expression of FTH1 protein
CTD PMID:32283200 PMID:38483099 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
JBrowse link
G Ftl1 ferritin light polypeptide 1 multiple interactions
increases expression
ISO
EXP
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of FTL mRNA
ferric ammonium citrate results in increased expression of FTL protein
ferric ammonium citrate results in increased expression of FTL1 protein
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:12393473 PMID:19913091 PMID:38483099 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein] CTD PMID:19515424 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Glb1 galactosidase, beta 1 increases expression ISO ferric ammonium citrate results in increased expression of GLB1 protein CTD PMID:38483099 NCBI chr 9:114,230,146...114,303,447
Ensembl chr 9:114,230,144...114,303,966
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein] CTD PMID:19515424 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845
JBrowse link
G H2ax H2A.X variant histone increases expression ISO ferric ammonium citrate results in increased expression of H2AX protein CTD PMID:38483099 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
ISO Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO ferric ammonium citrate results in increased expression of HMOX1 protein
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ferric ammonium citrate results in increased expression of HMOX1 protein]
CTD PMID:12393473 PMID:16439612 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hspa1a heat shock protein 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein] CTD PMID:19515424 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa1l heat shock protein 1-like multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261
JBrowse link
G Hspa9 heat shock protein 9 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein] CTD PMID:19515424 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL1B protein] CTD PMID:24862973 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of IL6 protein] CTD PMID:24862973 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins1 insulin I multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] CTD PMID:32283200 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Ins2 insulin II multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] CTD PMID:32283200 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases expression
decreases activity
ISO
EXP
ferric ammonium citrate results in decreased expression of IREB2 protein
ferric ammonium citrate results in decreased activity of IREB2 protein
CTD PMID:11054110 PMID:17469137 PMID:18073202 NCBI chr 9:54,769,942...54,819,812
Ensembl chr 9:54,771,073...54,819,814
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP ferric ammonium citrate inhibits the reaction [bathophenanthroline disulfonic acid results in decreased expression of LCN2 protein] CTD PMID:17350462 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein; BECN1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]; BECN1 protein affects the reaction [Hydrogen Peroxide inhibits the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]]; Chloroquine promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [olaparib promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]]; Hydrogen Peroxide inhibits the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]; Hydrogen Peroxide inhibits the reaction [Chloroquine promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]]; olaparib promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]; olaparib promotes the reaction [Chloroquine promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]]; PARP1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]; PARP1 protein affects the reaction [Chloroquine promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]]; SIRT1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein] CTD PMID:34826546 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK1 protein
ferric ammonium citrate results in increased phosphorylation of MAPK1 protein
CTD PMID:17191120 PMID:25858758 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 increases phosphorylation ISO ferric ammonium citrate results in increased phosphorylation of MAPK14 protein CTD PMID:17191120 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK3 protein
ferric ammonium citrate results in increased phosphorylation of MAPK3 protein
CTD PMID:17191120 PMID:25858758 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 1:42,890,393...42,944,843
Ensembl chr 1:42,890,393...42,944,843
JBrowse link
G Mt2 metallothionein 2 multiple interactions ISO [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 NCBI chr14:31,881,884...31,901,210
Ensembl chr14:31,881,822...31,901,812
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA] CTD PMID:9826428 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Oga O-GlcNAcase multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of OGA protein] CTD PMID:24862973 NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276
JBrowse link
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein] CTD PMID:19515424 NCBI chr10:59,159,019...59,209,126
Ensembl chr10:59,159,118...59,209,126
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in decreased expression of PARP1 protein; PARP1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of SIRT1 protein]; PARP1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]; PARP1 protein affects the reaction [Chloroquine promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]]; SIRT1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in decreased expression of PARP1 protein] CTD PMID:34826546 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pdhb pyruvate dehydrogenase (lipoamide) beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein] CTD PMID:19515424 NCBI chr14:14,296,470...14,303,782
Ensembl chr14:14,296,748...14,303,777
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein] CTD PMID:19515424 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein] CTD PMID:19515424 NCBI chr11:6,365,867...6,369,817
Ensembl chr11:6,365,443...6,369,817
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of PTGS2 mRNA] CTD PMID:24862973 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein] CTD PMID:19515424 NCBI chr11:48,691,187...48,697,068
Ensembl chr11:48,691,159...48,697,261
JBrowse link
G Runx2 runt related transcription factor 2 decreases expression
multiple interactions
EXP ferric ammonium citrate results in decreased expression of RUNX2 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Niacin inhibits the reaction [ferric ammonium citrate results in decreased expression of RUNX2 protein]]; Niacin inhibits the reaction [ferric ammonium citrate results in decreased expression of RUNX2 protein]; Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of RUNX2 protein]
CTD PMID:36087815 PMID:38081572 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression
ISO
EXP
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of SIRT1 protein; olaparib promotes the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of SIRT1 protein]; PARP1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of SIRT1 protein]; SIRT1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in decreased expression of PARP1 protein]; SIRT1 protein affects the reaction [[ferric ammonium citrate results in increased abundance of Iron] which results in increased lipidation of MAP1LC3B protein]
ferric ammonium citrate results in decreased expression of SIRT1 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Niacin inhibits the reaction [ferric ammonium citrate results in decreased expression of SIRT1 protein]]; Niacin inhibits the reaction [ferric ammonium citrate results in decreased expression of SIRT1 protein]; Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of SIRT1 protein]
CTD PMID:34826546 PMID:36087815 PMID:38081572 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 increases expression EXP ferric ammonium citrate results in increased expression of SLC11A1 mRNA CTD PMID:11054110 NCBI chr 1:74,414,318...74,429,974
Ensembl chr 1:74,414,354...74,425,221
JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 increases expression EXP ferric ammonium citrate results in increased expression of SLC11A2 mRNA CTD PMID:11054110 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953
JBrowse link
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of SLC40A1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:19913091 NCBI chr 1:45,947,230...45,965,690
Ensembl chr 1:45,947,228...45,965,683
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of SOD1 mRNA] CTD PMID:24862973 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions
decreases expression
ISO
EXP
Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of SOD2 protein]
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Niacin inhibits the reaction [ferric ammonium citrate results in decreased expression of SOD2 protein]]; Niacin inhibits the reaction [ferric ammonium citrate results in decreased expression of SOD2 protein]; Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of SOD2 protein]
CTD PMID:36087815 PMID:38081572 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO ferric ammonium citrate results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr 5:137,568,127...137,586,344
Ensembl chr 5:137,568,102...137,585,743
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO
EXP
ferric ammonium citrate results in decreased expression of TFRC mRNA; ferric ammonium citrate results in decreased expression of TFRC protein
[ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of TFRC mRNA
CTD PMID:11054110 PMID:12393473 PMID:16760464 PMID:18073202 PMID:25633564 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of TNF protein] CTD PMID:24862973 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tpd52l1 tumor protein D52-like 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein] CTD PMID:19515424 NCBI chr10:31,208,369...31,321,989
Ensembl chr10:31,208,372...31,321,954
JBrowse link
G Trf transferrin multiple interactions ISO ferric ammonium citrate inhibits the reaction [TF protein results in increased uptake of Iron] CTD PMID:11335103 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
JBrowse link
G Trp53 transformation related protein 53 increases expression ISO ferric ammonium citrate results in increased expression of TP53 protein CTD PMID:38483099 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein] CTD PMID:19515424 NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
gadobutrol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression EXP gadobutrol results in decreased expression of ADIPOQ mRNA CTD PMID:37437671 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression EXP gadobutrol results in decreased expression of FABP4 mRNA CTD PMID:37437671 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression EXP gadobutrol results in decreased expression of PPARG mRNA CTD PMID:37437671 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
gadodiamide hydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression EXP gadodiamide results in decreased expression of ADIPOQ mRNA; gadodiamide results in decreased expression of ADIPOQ protein CTD PMID:37437671 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions
ISO gadodiamide results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein]
CTD PMID:19561517 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression ISO gadodiamide results in increased expression of ALDH1A1 mRNA CTD PMID:20959327 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO gadodiamide results in increased expression of ANKRD22 mRNA CTD PMID:20959327 NCBI chr19:34,099,949...34,143,441
Ensembl chr19:34,098,869...34,143,453
JBrowse link
G Atm ataxia telangiectasia mutated increases expression ISO gadodiamide results in increased expression of ATM mRNA CTD PMID:20959327 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Atp8b1 ATPase, class I, type 8B, member 1 increases expression ISO gadodiamide results in increased expression of ATP8B1 mRNA CTD PMID:20959327 NCBI chr18:64,662,050...64,794,342
Ensembl chr18:64,662,038...64,794,338
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
ISO gadodiamide results in increased expression of CCL2 mRNA
gadodiamide results in increased expression of CCL2 mRNA; gadodiamide results in increased expression of CCL2 protein
gadodiamide results in increased secretion of CCL2 protein
CTD PMID:20938346 PMID:20959327 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO gadodiamide results in increased expression of CCL4 protein CTD PMID:20938346 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO gadodiamide results in increased expression of CCL7 protein CTD PMID:20938346 NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
JBrowse link
G Ccl8 C-C motif chemokine ligand 8 increases secretion
increases expression
ISO gadodiamide results in increased secretion of CCL8 protein
gadodiamide results in increased expression of CCL8 mRNA
CTD PMID:20959327 NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625
JBrowse link
G Cep15 centrosomal protein 15 increases expression ISO gadodiamide results in increased expression of CEP15 mRNA CTD PMID:20959327 NCBI chr14:10,147,278...10,185,610
Ensembl chr14:10,166,532...10,185,590
Ensembl chr14:10,166,532...10,185,590
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
increases secretion
ISO gadodiamide results in increased expression of CXCL10 mRNA
gadodiamide results in increased expression of CXCL10 protein
gadodiamide results in increased secretion of CXCL10 protein
CTD PMID:20938346 PMID:20959327 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 increases secretion
increases expression
ISO gadodiamide results in increased secretion of CXCL11 protein
gadodiamide results in increased expression of CXCL11 mRNA
CTD PMID:20959327 NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO gadodiamide results in increased expression of CXCL12 mRNA CTD PMID:20959327 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO gadodiamide results in increased expression of CXCL9 mRNA CTD PMID:20959327 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression EXP gadodiamide results in decreased expression of FABP4 mRNA; gadodiamide results in decreased expression of FABP4 protein CTD PMID:37437671 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO gadodiamide results in increased expression of IDO1 mRNA CTD PMID:20959327 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025
JBrowse link
G Ifi44l interferon-induced protein 44 like increases expression ISO gadodiamide results in increased expression of IFI44L mRNA CTD PMID:20959327 NCBI chr 3:151,464,374...151,468,528
Ensembl chr 3:151,464,374...151,468,529
JBrowse link
G Ifit1bl1 interferon induced protein with tetratricpeptide repeats 1B like 1 increases expression ISO gadodiamide results in increased expression of IFIT1 mRNA CTD PMID:20959327 NCBI chr19:34,570,288...34,640,382
Ensembl chr19:34,570,291...34,579,356
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO gadodiamide results in increased expression of IFIT3 mRNA CTD PMID:20959327 NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131
JBrowse link
G Ifng interferon gamma increases expression ISO gadodiamide results in increased expression of IFNG mRNA; gadodiamide results in increased expression of IFNG protein CTD PMID:19404939 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il13 interleukin 13 increases expression ISO gadodiamide results in increased expression of IL13 mRNA; gadodiamide results in increased expression of IL13 protein CTD PMID:19404939 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO gadodiamide results in increased expression of IL1A protein CTD PMID:20938346 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il4 interleukin 4 increases expression
affects expression
ISO gadodiamide results in increased expression of IL4 protein
gadodiamide affects the expression of IL4 mRNA
CTD PMID:19404939 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il4i1 interleukin 4 induced 1 increases expression ISO gadodiamide results in increased expression of IL4I1 mRNA CTD PMID:20959327 NCBI chr 7:44,485,712...44,490,233
Ensembl chr 7:44,465,811...44,490,233
JBrowse link
G Il6 interleukin 6 affects expression
increases expression
ISO gadodiamide affects the expression of IL6 protein
gadodiamide results in increased expression of IL6 mRNA
CTD PMID:19404939 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Kitl kit ligand increases expression ISO gadodiamide results in increased expression of KITLG protein CTD PMID:20938346 NCBI chr10:99,851,477...99,936,278
Ensembl chr10:99,851,492...99,936,278
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein] CTD PMID:19561517 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein] CTD PMID:19561517 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]
gadodiamide results in increased expression of MMP1 mRNA; gadodiamide results in increased expression of MMP1 protein
CTD PMID:19561517 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression ISO gadodiamide results in increased expression of NOS2 protein CTD PMID:20959327 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nxpe3 neurexophilin and PC-esterase domain family, member 3 increases expression ISO gadodiamide results in increased expression of NXPE3 mRNA CTD PMID:20959327 NCBI chr16:55,660,316...55,717,467
Ensembl chr16:55,660,316...55,715,648
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression EXP gadodiamide results in decreased expression of PPARG mRNA; gadodiamide results in decreased expression of PPARG protein CTD PMID:37437671 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases localization ISO gadodiamide results in increased localization of RELA protein CTD PMID:20959327 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rhoq ras homolog family member Q increases expression ISO gadodiamide results in increased expression of RHOQ mRNA CTD PMID:20959327 NCBI chr17:87,270,539...87,307,497
Ensembl chr17:87,270,510...87,307,497
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO gadodiamide results in increased expression of RIT1 mRNA CTD PMID:20959327 NCBI chr 3:88,624,154...88,638,354
Ensembl chr 3:88,624,145...88,638,356
JBrowse link
G Rnf125 ring finger protein 125 increases expression ISO gadodiamide results in increased expression of RNF125 mRNA CTD PMID:20959327 NCBI chr18:21,077,672...21,120,416
Ensembl chr18:21,077,682...21,116,919
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO gadodiamide results in increased expression of RSAD2 mRNA CTD PMID:20959327 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451
JBrowse link
G Rsl1 regulator of sex limited protein 1 increases expression ISO gadodiamide results in increased expression of ZNF595 mRNA CTD PMID:20959327 NCBI chr13:67,321,238...67,332,108
Ensembl chr13:67,321,195...67,332,108
JBrowse link
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 increases expression ISO gadodiamide results in increased expression of SLC39A10 mRNA CTD PMID:20959327 NCBI chr 1:46,846,704...46,964,952
Ensembl chr 1:46,846,704...46,932,012
JBrowse link
G Spn sialophorin increases expression ISO gadodiamide results in increased expression of SPN mRNA CTD PMID:20959327 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO gadodiamide results in increased expression of SPP1 protein CTD PMID:20938346 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO gadodiamide results in increased expression of TGFB1 mRNA; gadodiamide results in increased expression of TGFB1 protein CTD PMID:19404939 PMID:20938346 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression
multiple interactions
ISO gadodiamide results in increased expression of TIMP1 mRNA; gadodiamide results in increased expression of TIMP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]
CTD PMID:19561517 PMID:20938346 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Ubd ubiquitin D increases expression ISO gadodiamide results in increased expression of UBD mRNA CTD PMID:20959327 NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO gadodiamide results in increased expression of VEGFA mRNA; gadodiamide results in increased expression of VEGFA protein CTD PMID:19404939 PMID:20938346 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO gadodiamide results in increased expression of WDR5 mRNA CTD PMID:20959327 NCBI chr 2:27,405,159...27,426,547
Ensembl chr 2:27,405,169...27,426,547
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO gadodiamide results in increased expression of XIAP mRNA CTD PMID:20959327 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Zfp652 zinc finger protein 652 increases expression ISO gadodiamide results in increased expression of ZNF652 mRNA CTD PMID:20959327 NCBI chr11:95,639,893...95,655,541
Ensembl chr11:95,603,499...95,725,941
JBrowse link

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  CHEBI ontology 22340
    role 22326
      application 21959
        pharmaceutical 21306
          diagnostic agent 783
            diagnostic imaging agent 577
              MRI contrast agent 421
                4-carboxy-TEMPO 1
                dimethyl sulfoxide + 332
                ferric ammonium citrate 69
                gadobutrol 3
                gadodiamide + 49
                gadopentetate + 0
                gadopentetate dimeglumine 0
                gadoterate meglumine 0
                gadoteric acid 0
                gadoteridol 0
                gadoversetamide 0
                manganese(II) chloride dihydrate 0
                manganese(II) chloride tetrahydrate 0
paths to the root