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Gene: Tra2b (transformer 2 beta) Mus musculus
Symbol: Tra2b
Name: transformer 2 beta
Description: Exhibits poly-purine tract binding activity and pre-mRNA binding activity. Involved in cerebral cortex regionalization; embryonic brain development; and regulation of mRNA splicing, via spliceosome. Localizes to nucleus. Colocalizes with nuclear inner membrane. Is expressed in central nervous system; extraembryonic ectoderm; olfactory epithelium; retina; and thymus. Orthologous to human TRA2B (transformer 2 beta homolog); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1,2-dichloroethane; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730405G21Rik; D16Ertd266e; MGC102169; Sfrs10; SIG-41; Silg41; silica-induced gene 41 protein; splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila); TRA-2 beta; TRA2-beta; TRA2beta; transformer 2 beta homolog; transformer 2 beta homolog (Drosophila); transformer-2 protein homolog B; transformer-2 protein homolog beta
Homo sapiens (human) : TRA2B (transformer 2 beta homolog)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tra2b (transformer 2 beta homolog)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tra2b (transformer 2 beta homolog)
Pan paniscus (bonobo/pygmy chimpanzee) : TRA2B (transformer 2 beta homolog)
Canis lupus familiaris (dog) : TRA2B (transformer 2 beta homolog)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tra2b (transformer 2 beta homolog)
Sus scrofa (pig) : TRA2B (transformer 2 beta homolog)
Chlorocebus sabaeus (African green monkey) : TRA2B (transformer 2 beta homolog)
Heterocephalus glaber (naked mole-rat) : Tra2b (transformer 2 beta homolog)
more info ...
Related Pseudogenes: Gm10254   Gm11957   Gm14639   Gm15667   Gm2975   Gm6439  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1622,244,549 - 22,266,005 (-)EnsemblGRCm38mm10GRCm38
GRCm381622,244,552 - 22,266,005 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371622,245,814 - 22,266,002 (-)NCBIGRCm37mm9NCBIm37
MGSCv361622,160,997 - 22,181,185 (-)NCBImm8
Celera1622,813,196 - 22,833,384 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tra2b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732516
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.