CHEBI ONTOLOGY - ANNOTATIONS |
|
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
|
Term: | diagnostic imaging agent |
|
Accession: | CHEBI:37334
|
browse the term
|
Definition: | A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease. |
|
|
|
G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
multiple interactions |
ISO |
Mefloquine inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] |
CTD |
PMID:16004972 |
|
NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
|
|
G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
increases export multiple interactions |
ISO |
ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; hesperetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; naringenin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Quercetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; resveratrol inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Silymarin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] |
CTD |
PMID:16156793 |
|
NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
|
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects transport multiple interactions increases export increases transport |
EXP ISO |
ABCC2 protein affects the transport of 5(6)-carboxy-2',7'-dichlorofluorescein 4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; cyanoginosin LR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Cyclosporine inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin RR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin-LF inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Tobacco Smoke Pollution inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog] ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog [ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 gene mutant form inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:19326901 PMID:21240898 PMID:21341280 PMID:23562342 PMID:24907646 PMID:24909372 PMID:24973091 PMID:25862123 PMID:27450509 PMID:31348918 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
|
|
G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
multiple interactions increases transport |
EXP ISO |
[ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:24907646 PMID:31348918 |
|
NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
|
|
G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
multiple interactions increases transport |
ISO |
Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] |
CTD |
PMID:31348918 |
|
NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
|
|
|
G |
Slc22a8 |
solute carrier family 22 member 8 |
multiple interactions increases transport |
ISO |
quercetin 3'-sulfate inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein] |
CTD |
PMID:21244849 |
|
NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
|
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
ISO |
ABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione] |
CTD |
PMID:16049127 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
|
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases export |
ISO |
ABCC1 protein results in increased export of 6-carboxyfluorescein |
CTD |
PMID:17940500 |
|
NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects export multiple interactions |
ISO |
ABCC2 protein affects the export of 6-carboxyfluorescein Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein] |
CTD |
PMID:11477083 |
|
NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
|
|
G |
Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions increases import |
ISO |
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein] |
CTD |
PMID:28629854 |
|
NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
|
|
G |
Slc22a8 |
solute carrier family 22 member 8 |
increases import multiple interactions |
ISO |
SLC22A8 protein results in increased import of 6-carboxyfluorescein 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine promotes the reaction [2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-9H-pyrido(2,3-b)indole promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 3-amino-1-methyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Cadmium Chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; lead chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; sodium arsenate promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein] |
CTD |
PMID:28629854 |
|
NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
|
|
|
G |
Agt |
angiotensinogen |
multiple interactions increases expression |
EXP |
telmisartan inhibits the reaction [Diatrizoate results in increased expression of AGT protein] |
CTD |
PMID:19452295 |
|
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
Plant Extracts inhibits the reaction [Diatrizoate results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:25603236 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[Diatrizoate co-treated with Iodine] results in increased expression of BAX protein |
CTD |
PMID:17173243 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
[Diatrizoate co-treated with Iodine] results in increased expression of BCL2 protein |
CTD |
PMID:17173243 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
|
|
G |
Casp3 |
caspase 3 |
affects expression multiple interactions increases activity |
ISO EXP |
Diatrizoate affects the expression of CASP3 protein [Diatrizoate co-treated with Iodine] results in increased activity of CASP3 protein telmisartan inhibits the reaction [Diatrizoate results in increased activity of CASP3 protein] |
CTD |
PMID:17173243 PMID:19452295 PMID:21036957 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
F2 |
coagulation factor II |
multiple interactions |
ISO |
Diatrizoate inhibits the reaction [F2 protein binds to SERPINC1 protein] |
CTD |
PMID:2020943 |
|
NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
|
|
G |
Foxo1 |
forkhead box O1 |
decreases phosphorylation multiple interactions |
ISO |
Diatrizoate results in decreased phosphorylation of FOXO1 protein Plant Extracts inhibits the reaction [Diatrizoate results in decreased phosphorylation of FOXO1 protein] |
CTD |
PMID:25603236 |
|
NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
|
|
G |
Foxo3 |
forkhead box O3 |
affects phosphorylation |
ISO |
Diatrizoate affects the phosphorylation of FOXO3 protein |
CTD |
PMID:21036957 |
|
NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
affects phosphorylation multiple interactions |
ISO |
Diatrizoate affects the phosphorylation of MAPK1 protein Plant Extracts affects the reaction [Diatrizoate affects the phosphorylation of MAPK1 protein] |
CTD |
PMID:25603236 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions affects phosphorylation |
ISO |
Plant Extracts affects the reaction [Diatrizoate affects the phosphorylation of MAPK3 protein] |
CTD |
PMID:25603236 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
Diatrizoate results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:21036957 |
|
NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
increases phosphorylation |
ISO |
Diatrizoate results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:21036957 |
|
NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
|
|
G |
Pim1 |
Pim-1 proto-oncogene, serine/threonine kinase |
decreases expression multiple interactions |
ISO |
Diatrizoate results in decreased expression of PIM1 protein Plant Extracts inhibits the reaction [Diatrizoate results in decreased expression of PIM1 protein] |
CTD |
PMID:25603236 |
|
NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases phosphorylation |
ISO |
Diatrizoate results in increased phosphorylation of RELA protein |
CTD |
PMID:21036957 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
Serpinc1 |
serpin family C member 1 |
multiple interactions |
ISO |
Diatrizoate inhibits the reaction [F2 protein binds to SERPINC1 protein] |
CTD |
PMID:2020943 |
|
NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
affects expression |
ISO |
Diatrizoate affects the expression of STAT3 protein modified form |
CTD |
PMID:21036957 |
|
NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
|
|
|
G |
Alb |
albumin |
increases expression |
EXP |
Barium Sulfate results in increased expression of ALB mRNA |
CTD |
PMID:29463257 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
|
|
G |
Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
EXP |
Barium Sulfate results in increased expression of BIRC5 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
|
|
G |
Ccl11 |
C-C motif chemokine ligand 11 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CCL11 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases secretion increases expression |
EXP |
Barium Sulfate results in increased secretion of CCL2 protein Barium Sulfate results in increased expression of CCL2 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
|
|
G |
Ccl20 |
C-C motif chemokine ligand 20 |
affects expression |
EXP |
Barium Sulfate affects the expression of CCL20 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
|
|
G |
Ccl22 |
C-C motif chemokine ligand 22 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CCL22 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
|
|
G |
Ccl24 |
C-C motif chemokine ligand 24 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CCL24 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625
|
|
G |
Ccl4 |
C-C motif chemokine ligand 4 |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of CCL4 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
|
|
G |
Ccl7 |
C-C motif chemokine ligand 7 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CCL7 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
|
|
G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CCR2 mRNA |
CTD |
PMID:29463257 |
|
|
|
G |
Cd40lg |
CD40 ligand |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of CD40LG mRNA |
CTD |
PMID:29463257 |
|
NCBI chr X:159,703,703...159,714,886
Ensembl chr X:159,703,578...159,716,562
|
|
G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CXCL9 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
|
|
G |
Cxcr3 |
C-X-C motif chemokine receptor 3 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CXCR3 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr X:71,614,346...71,616,997
Ensembl chr X:71,614,346...71,616,997
|
|
G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CYP4A1 mRNA |
CTD |
PMID:11124224 |
|
NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
|
|
G |
Cyp4a2 |
cytochrome P450, family 4, subfamily a, polypeptide 2 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CYP4A2 mRNA |
CTD |
PMID:11124224 |
|
NCBI chr 5:134,196,910...134,207,888
Ensembl chr 5:134,196,912...134,207,863
|
|
G |
Cyp4a3 |
cytochrome P450, family 4, subfamily a, polypeptide 3 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CYP4A3 mRNA |
CTD |
PMID:11124224 |
|
NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
|
|
G |
Cyp4f1 |
cytochrome P450, family 4, subfamily f, polypeptide 1 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CYP4F1 mRNA |
CTD |
PMID:14644421 |
|
NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
|
|
G |
Cyp4f4 |
cytochrome P450, family 4, subfamily f, polypeptide 4 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CYP4F4 mRNA |
CTD |
PMID:14644421 |
|
NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
|
|
G |
Cyp4f6 |
cytochrome P450, family 4, subfamily f, polypeptide 6 |
increases expression |
EXP |
Barium Sulfate results in increased expression of CYP4F6 mRNA |
CTD |
PMID:14644421 |
|
NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410
|
|
G |
Exo1 |
exonuclease 1 |
affects expression |
EXP |
Barium Sulfate affects the expression of EXO1 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
|
|
G |
Fabp4 |
fatty acid binding protein 4 |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of FABP4 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
|
|
G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of HBA1 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
|
|
G |
Il2rb |
interleukin 2 receptor subunit beta |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of IL2RB mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
|
|
G |
Il6 |
interleukin 6 |
increases expression |
ISO |
Barium Sulfate results in increased expression of IL6 protein |
CTD |
PMID:11403239 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Krt1 |
keratin 1 |
increases expression |
EXP |
Barium Sulfate results in increased expression of KRT1 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 7:143,448,318...143,453,544
Ensembl chr 7:143,448,318...143,453,544
|
|
G |
Lig4 |
DNA ligase 4 |
increases expression |
EXP |
Barium Sulfate results in increased expression of LIG4 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
|
|
G |
Lpo |
lactoperoxidase |
increases expression |
EXP |
Barium Sulfate results in increased expression of LPO mRNA; Barium Sulfate results in increased expression of LPO protein |
CTD |
PMID:29463257 |
|
NCBI chr10:75,100,385...75,120,247
Ensembl chr10:75,100,385...75,120,247
|
|
G |
Mmp12 |
matrix metallopeptidase 12 |
increases expression |
EXP |
Barium Sulfate results in increased expression of MMP12 mRNA; Barium Sulfate results in increased expression of MMP12 protein |
CTD |
PMID:29463257 |
|
NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
|
|
G |
Mutyh |
mutY DNA glycosylase |
increases expression |
EXP |
Barium Sulfate results in increased expression of MUTYH mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
|
|
G |
Ngb |
neuroglobin |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of NGB mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 6:111,126,259...111,131,699
Ensembl chr 6:111,126,261...111,132,320
|
|
G |
Noxo1 |
NADPH oxidase organizer 1 |
increases expression |
EXP |
Barium Sulfate results in increased expression of NOXO1 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:14,062,331...14,066,918
Ensembl chr10:14,062,331...14,066,918
|
|
G |
Opcml |
opioid binding protein/cell adhesion molecule-like |
increases expression |
EXP |
Barium Sulfate results in increased expression of OPCML mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 8:28,842,202...29,967,300
Ensembl chr 8:29,453,643...29,962,825
|
|
G |
Pf4 |
platelet factor 4 |
increases expression |
EXP |
Barium Sulfate results in increased expression of PF4 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
|
|
G |
Scd |
stearoyl-CoA desaturase |
affects expression |
EXP |
Barium Sulfate affects the expression of SCD1 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
|
|
G |
Tcf21 |
transcription factor 21 |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of TCF21 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
|
|
G |
Thbs2 |
thrombospondin 2 |
increases expression |
EXP |
Barium Sulfate results in increased expression of THBS2 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
|
|
G |
Top2a |
DNA topoisomerase II alpha |
increases expression |
EXP |
Barium Sulfate results in increased expression of TOP2A mRNA |
CTD |
PMID:29463257 |
|
NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
|
|
G |
Txnip |
thioredoxin interacting protein |
decreases expression |
EXP |
Barium Sulfate results in decreased expression of TXNIP mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
|
|
G |
Xrcc2 |
X-ray repair cross complementing 2 |
increases expression |
EXP |
Barium Sulfate results in increased expression of XRCC2 mRNA |
CTD |
PMID:29463257 |
|
NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
|
|
|
G |
A2m |
alpha-2-macroglobulin |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of A2M mRNA |
CTD |
PMID:12883083 |
|
NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
|
|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of ABCB1 mRNA |
CTD |
PMID:12843640 |
|
NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
|
|
G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] |
CTD |
PMID:11682029 |
|
NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
|
|
G |
Actc1 |
actin, alpha, cardiac muscle 1 |
increases expression decreases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of ACTC1 mRNA Dimethyl Sulfoxide results in decreased expression of ACTC1 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
|
|
G |
Agrp |
agouti related neuropeptide |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of AGRP mRNA |
CTD |
PMID:24834073 |
|
NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011
|
|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions decreases expression |
ISO |
Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter] Dimethyl Sulfoxide results in decreased expression of AHR mRNA |
CTD |
PMID:16675542 PMID:22486318 |
|
NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
|
|
G |
Aicda |
activation-induced cytidine deaminase |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of AICDA mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
|
|
G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions affects localization |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Acetaminophen affects the localization of AIFM1 protein] Dimethyl Sulfoxide affects the localization of AIFM1 protein |
CTD |
PMID:20423716 PMID:22535522 |
|
NCBI chr X:135,304,063...135,343,062
Ensembl chr X:135,304,066...135,343,087
|
|
G |
Alas2 |
5'-aminolevulinate synthase 2 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of ALAS2 mRNA |
CTD |
PMID:21296123 |
|
NCBI chr X:23,167,576...23,187,356
Ensembl chr X:23,167,696...23,187,341
|
|
G |
Alb |
albumin |
decreases expression |
ISO EXP |
Dimethyl Sulfoxide results in decreased expression of ALB mRNA Dimethyl Sulfoxide results in decreased expression of ALB mRNA; Dimethyl Sulfoxide results in decreased expression of ALB protein |
CTD |
PMID:14757319 PMID:22105179 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
|
|
G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
|
|
G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein] |
CTD |
PMID:23751068 |
|
NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
|
|
G |
Apoa1 |
apolipoprotein A1 |
increases expression increases activity |
ISO EXP |
Dimethyl Sulfoxide results in increased expression of APOA1 mRNA; Dimethyl Sulfoxide results in increased expression of APOA1 protein Dimethyl Sulfoxide results in increased activity of APOA1 promoter |
CTD |
PMID:16423621 |
|
NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
|
|
G |
Apom |
apolipoprotein M |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of APOM mRNA |
CTD |
PMID:24834073 |
|
NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
|
|
G |
Aqp1 |
aquaporin 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of AQP1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
|
|
G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Androgens results in increased activity of AR protein] |
CTD |
PMID:28377212 |
|
NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
|
|
G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter] |
CTD |
PMID:16675542 |
|
NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
|
|
G |
Arpc4 |
actin related protein 2/3 complex, subunit 4 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of ARPC4 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
|
|
G |
Atf3 |
activating transcription factor 3 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of ATF3 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
|
|
G |
Atp1a2 |
ATPase Na+/K+ transporting subunit alpha 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of ATP1A2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
|
|
G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of ATP1B1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
|
|
G |
Atp1b3 |
ATPase Na+/K+ transporting subunit beta 3 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of ATP1B3 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
|
|
G |
Atp5mf |
ATP synthase membrane subunit f |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of ATP5MF mRNA |
CTD |
PMID:24834073 |
|
NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
|
|
G |
Aurkaip1 |
aurora kinase A interacting protein 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of AURKAIP1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 5:173,274,433...173,276,170
Ensembl chr 5:173,256,637...173,276,169
|
|
G |
Barhl2 |
BarH-like homeobox 2 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of BARHL2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr14:4,362,717...4,367,614
Ensembl chr14:4,362,717...4,367,605
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO |
Dimethyl Sulfoxide results in increased expression of BAX mRNA Quercetin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of BAX mRNA] |
CTD |
PMID:17652743 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bend6 |
BEN domain containing 6 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of BEND6 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 9:38,297,253...38,351,312
Ensembl chr 9:38,297,322...38,351,024
|
|
G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of BTG2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
|
|
G |
Cad |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] |
CTD |
PMID:16675542 |
|
NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
|
|
G |
Cadm1 |
cell adhesion molecule 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of CADM1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases cleavage |
EXP ISO |
Dimethyl Sulfoxide results in decreased cleavage of and results in decreased activity of CASP3 protein Dimethyl Sulfoxide results in increased cleavage of CASP3 protein |
CTD |
PMID:12370186 PMID:22535522 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Cat |
catalase |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA] |
CTD |
PMID:9169468 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases secretion decreases expression |
ISO EXP |
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Dimethyl Sulfoxide results in increased secretion of CCL2 protein] Dimethyl Sulfoxide results in decreased expression of CCL2 mRNA Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of CCL2 mRNA] |
CTD |
PMID:10925121 PMID:14576080 PMID:15689417 PMID:17529908 PMID:21878375 PMID:26860701 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
|
|
G |
Ccl28 |
C-C motif chemokine ligand 28 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CCL28 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein] |
CTD |
PMID:21878375 |
|
NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
|
|
G |
Cd14 |
CD14 molecule |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of CD14 protein |
CTD |
PMID:26036281 |
|
NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
|
|
G |
Cd38 |
CD38 molecule |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]] |
CTD |
PMID:15964820 |
|
NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
|
|
G |
Cd3g |
CD3g molecule |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CD3G mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
|
|
G |
Cd59 |
CD59 molecule |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased mutagenesis of CD59 gene] |
CTD |
PMID:12361925 PMID:15033018 |
|
NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
|
|
G |
Cdc25b |
cell division cycle 25B |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of CDC25B mRNA |
CTD |
PMID:21296123 |
|
NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
|
|
G |
Cdh1 |
cadherin 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of CDH1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
|
|
G |
Ceacam19 |
CEA cell adhesion molecule 19 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CEACAM19 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:80,800,951...80,809,769
Ensembl chr 1:80,800,951...80,809,769
|
|
G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of CEBPB mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
|
|
G |
Cfap300 |
cilia and flagella associated protein 300 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CFAP300 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 8:6,218,391...6,236,438
Ensembl chr 8:6,218,393...6,235,967
|
|
G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CFLAR mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
|
|
G |
Cgref1 |
cell growth regulator with EF hand domain 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CGREF1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
|
|
G |
Chek2 |
checkpoint kinase 2 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CHEK2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
|
|
G |
Cklf |
chemokine-like factor |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CKLF mRNA |
CTD |
PMID:24834073 |
|
NCBI chr19:903,609...914,880
Ensembl chr19:906,411...914,880
|
|
G |
Cldn6 |
claudin 6 |
multiple interactions decreases methylation increases expression |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN6 mRNA] Dimethyl Sulfoxide results in decreased methylation of CLDN6 promoter Dimethyl Sulfoxide results in increased expression of CLDN6 mRNA |
CTD |
PMID:18661270 |
|
NCBI chr10:12,999,256...13,002,860
Ensembl chr10:13,000,090...13,002,862
|
|
G |
Cldn8 |
claudin 8 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of CLDN8 mRNA |
CTD |
PMID:18661270 |
|
NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
|
|
G |
Cldn9 |
claudin 9 |
multiple interactions increases expression decreases methylation |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN9 mRNA] Dimethyl Sulfoxide results in increased expression of CLDN9 mRNA Dimethyl Sulfoxide results in decreased methylation of CLDN9 promoter |
CTD |
PMID:18661270 |
|
NCBI chr10:13,003,010...13,004,441
Ensembl chr10:13,003,011...13,004,441
|
|
G |
Cntf |
ciliary neurotrophic factor |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CNTF mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
|
|
G |
Col11a1 |
collagen type XI alpha 1 chain |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of COL11A1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein] |
CTD |
PMID:11682029 |
|
NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
|
|
G |
Col4a1 |
collagen type IV alpha 1 chain |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of COL4A1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
|
|
G |
Col4a5 |
collagen type IV alpha 5 chain |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of COL4A5 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr X:112,769,595...112,983,720
Ensembl chr X:112,769,645...112,983,685
|
|
G |
Col5a1 |
collagen type V alpha 1 chain |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of COL5A1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
|
|
G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of COX4I1 protein |
CTD |
PMID:27385396 |
|
NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
|
|
G |
Cp |
ceruloplasmin |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of CP mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
|
|
G |
Cpm |
carboxypeptidase M |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of CPM mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 7:60,654,350...60,714,620
Ensembl chr 7:60,654,350...60,714,620
|
|
G |
Cs |
citrate synthase |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] |
CTD |
PMID:27385396 |
|
NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
|
|
G |
Csf1r |
colony stimulating factor 1 receptor |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of CSF1R mRNA |
CTD |
PMID:8445950 |
|
NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
|
|
G |
Cth |
cystathionine gamma-lyase |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CTH mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
|
|
G |
Ctnnb1 |
catenin beta 1 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of CTNNB1 protein |
CTD |
PMID:20091315 |
|
NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
|
|
G |
Cuta |
cutA divalent cation tolerance homolog |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CUTA mRNA |
CTD |
PMID:24834073 |
|
NCBI chr20:5,532,024...5,533,640
Ensembl chr20:5,532,024...5,533,620
|
|
G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CXCL14 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
|
|
G |
Cxxc4 |
CXXC finger protein 4 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CXXC4 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 2:239,414,882...239,439,640
Ensembl chr 2:239,415,046...239,439,568
|
|
G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [adrenocorticotropin zinc results in decreased expression of CYP11B2 mRNA]; Dimethyl Sulfoxide promotes the reaction [adrenocorticotropin zinc results in decreased activity of CYP11B2 protein] |
CTD |
PMID:10822027 |
|
NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
affects expression increases expression multiple interactions |
ISO |
Dimethyl Sulfoxide affects the expression of CYP1A1 mRNA Dimethyl Sulfoxide results in increased expression of CYP1A1 protein Dimethyl Sulfoxide results in increased expression of CYP1A1 mRNA Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] |
CTD |
PMID:12147272 PMID:12843640 PMID:22486318 PMID:31096615 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
|
|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
affects expression increases expression multiple interactions |
ISO |
Dimethyl Sulfoxide affects the expression of CYP1A2 mRNA Dimethyl Sulfoxide results in increased expression of CYP1A2 mRNA [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2 |
CTD |
PMID:12843640 PMID:18347083 PMID:30262279 |
|
NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA |
CTD |
PMID:12843640 |
|
NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
|
|
G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]] |
CTD |
PMID:15964820 |
|
NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
|
|
G |
Cyp2a2 |
cytochrome P450, family 2, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline] |
CTD |
PMID:19858067 |
|
NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
|
|
G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions |
EXP ISO |
Dimethyl Sulfoxide inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin] [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein] |
CTD |
PMID:19858067 PMID:20371638 |
|
NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
|
|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of CYP2B6 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2B6 protein |
CTD |
PMID:30262279 PMID:31096615 |
|
NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
|
|
G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] |
CTD |
PMID:19858067 |
|
NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
|
|
G |
Cyp2c24 |
cytochrome P450, family 2, subfamily c, polypeptide 24 |
multiple interactions |
ISO |
[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA; [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] |
CTD |
PMID:20371638 |
|
NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
|
|
G |
Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] |
CTD |
PMID:19858067 |
|
NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
|
|
G |
Cyp2d2 |
cytochrome P450, family 2, subfamily d, polypeptide 2 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] |
CTD |
PMID:19858067 |
|
NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
|
|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]] |
CTD |
PMID:11368792 |
|
NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
affects expression increases expression increases activity multiple interactions |
ISO EXP |
Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA Dimethyl Sulfoxide results in increased expression of CYP2E1 protein Dimethyl Sulfoxide results in increased activity of CYP2E1 protein Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide] Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2E1 protein Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]] |
CTD |
PMID:1538706 PMID:3113478 PMID:3337723 PMID:8074729 PMID:9143349 PMID:12147272 PMID:12843640 PMID:17177172 PMID:19858067 PMID:30262279 PMID:31096615 |
|
NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline] |
CTD |
PMID:19858067 |
|
NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
|
|
G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline] |
CTD |
PMID:19858067 |
|
NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
|
|
G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
multiple interactions affects expression increases expression |
ISO |
[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA; [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP3A4; Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; trichostatin A affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]] Dimethyl Sulfoxide affects the expression of CYP3A4 mRNA Dimethyl Sulfoxide results in increased expression of CYP3A4 mRNA; Dimethyl Sulfoxide results in increased expression of CYP3A4 protein |
CTD |
PMID:12843640 PMID:18347083 PMID:30262279 PMID:31096615 PMID:31877331 |
|
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
|
|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CYP3A5 mRNA |
CTD |
PMID:12843640 |
|
NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
|
|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases expression |
EXP |
DMSO increases expression of Cyp7a1 mRNA in rat liver; reaction inhibited by INT-767 |
RGD |
PMID:30038487 |
RGD:15092090 |
NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
|
|
G |
Cysrt1 |
cysteine rich tail 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of CYSRT1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:2,458,295...2,462,037
Ensembl chr 3:2,458,295...2,459,385
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of DDIT3 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
|
|
G |
Depp1 |
DEPP1, autophagy regulator |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of DEPP1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
|
|
G |
Dffa |
DNA fragmentation factor subunit alpha |
increases cleavage |
ISO |
Dimethyl Sulfoxide results in increased cleavage of DFFA protein |
CTD |
PMID:22535522 |
|
NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
|
|
G |
Dmap1 |
DNA methyltransferase 1-associated protein 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of DMAP1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 5:136,533,791...136,541,795
Ensembl chr 5:136,533,792...136,541,795
|
|
G |
Dnajb5 |
DnaJ heat shock protein family (Hsp40) member B5 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of DNAJB5 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 5:58,393,197...58,402,162
Ensembl chr 5:58,393,233...58,401,870
|
|
G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of DNAJB9 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
|
|
G |
Dnmt1 |
DNA methyltransferase 1 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of DNMT1 protein |
CTD |
PMID:17065238 |
|
NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of DUSP1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
|
|
G |
Eaf2 |
ELL associated factor 2 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of EAF2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr11:66,878,658...66,923,092
Ensembl chr11:66,878,658...66,923,092
|
|
G |
Edn2 |
endothelin 2 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of EDN2 mRNA |
CTD |
PMID:15619356 |
|
NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
|
|
G |
Ednra |
endothelin receptor type A |
multiple interactions |
EXP |
[Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein |
CTD |
PMID:20561571 |
|
NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
|
|
G |
Ednrb |
endothelin receptor type B |
multiple interactions increases expression |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein] Dimethyl Sulfoxide results in increased expression of EDNRB mRNA; Dimethyl Sulfoxide results in increased expression of EDNRB protein |
CTD |
PMID:20561571 |
|
NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
|
|
G |
Eef1akmt1 |
EEF1A lysine methyltransferase 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of EEF1AKMT1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr15:37,813,115...37,830,932
Ensembl chr15:37,813,115...37,831,031
|
|
G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of EFEMP1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
|
|
G |
Egr1 |
early growth response 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of EGR1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
|
|
G |
Eif4g2 |
eukaryotic translation initiation factor 4, gamma 2 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of EIF4G2 protein |
CTD |
PMID:18491231 |
|
NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
|
|
G |
Emp1 |
epithelial membrane protein 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of EMP1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
|
|
G |
Endog |
endonuclease G |
affects localization |
ISO |
Dimethyl Sulfoxide affects the localization of ENDOG protein |
CTD |
PMID:22535522 |
|
NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
|
|
G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of ENPP2 protein |
CTD |
PMID:22952646 |
|
NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
|
|
G |
Eppin |
epididymal peptidase inhibitor |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of EPPIN mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:161,043,761...161,050,550
Ensembl chr 3:161,041,727...161,050,557
|
|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter] |
CTD |
PMID:16675542 |
|
NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
|
|
G |
Eva1b |
eva-1 homolog B |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of EVA1B mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 5:144,160,026...144,161,421
Ensembl chr 5:144,160,108...144,161,410
|
|
G |
Fas |
Fas cell surface death receptor |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of FAS protein |
CTD |
PMID:15998540 |
|
NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
|
|
G |
Faslg |
Fas ligand |
decreases expression |
EXP |
Dimethyl Sulfoxide results in decreased expression of FASLG mRNA |
CTD |
PMID:10925121 |
|
NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
|
|
G |
Fbxl21 |
F-box and leucine-rich repeat protein 21 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of FBXL21P mRNA |
CTD |
PMID:24834073 |
|
NCBI chr17:8,505,771...8,520,208
Ensembl chr17:8,505,996...8,520,147
|
|
G |
Fgg |
fibrinogen gamma chain |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of FGG mRNA; Dimethyl Sulfoxide results in increased expression of FGG protein |
CTD |
PMID:14757319 |
|
NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
|
|
G |
Flnc |
filamin C |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of FLNC mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
|
|
G |
Fmr1 |
FMRP translational regulator 1 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] |
CTD |
PMID:27385396 |
|
NCBI chr X:154,684,924...154,722,369
Ensembl chr X:154,684,935...154,722,314
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of FOS mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
|
|
G |
Foxa2 |
forkhead box A2 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of FOXA2 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
|
|
G |
Frs3 |
fibroblast growth factor receptor substrate 3 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of FRS3 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 9:15,297,794...15,306,850
Ensembl chr 9:15,297,895...15,306,465
|
|
G |
Gad1 |
glutamate decarboxylase 1 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of GAD1 mRNA |
CTD |
PMID:17065238 |
|
NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of GADD45A mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
|
|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of GADD45G mRNA |
CTD |
PMID:22193206 |
|
NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
|
|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of GAPDH mRNA |
CTD |
PMID:12843640 |
|
NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
|
|
G |
Gata4 |
GATA binding protein 4 |
decreases expression increases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of GATA4 mRNA Dimethyl Sulfoxide results in increased expression of GATA4 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
|
|
G |
Gata6 |
GATA binding protein 6 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of GATA6 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
|
|
G |
Gja1 |
gap junction protein, alpha 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of GJA1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
|
|
G |
Gjb1 |
gap junction protein, beta 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of GJB1 mRNA |
CTD |
PMID:8631141 |
|
NCBI chr X:71,272,030...71,279,973
Ensembl chr X:71,272,042...71,279,977
|
|
G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of GJB2 mRNA |
CTD |
PMID:8631141 |
|
NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
|
|
G |
Glt8d1 |
glycosyltransferase 8 domain containing 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of GLT8D1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr16:7,082,450...7,097,405
Ensembl chr16:7,082,450...7,097,401
|
|
G |
Gng3 |
G protein subunit gamma 3 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of GNG3 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:225,033,921...225,035,687
Ensembl chr 1:225,033,921...225,035,687
|
|
G |
Gpbar1 |
G protein-coupled bile acid receptor 1 |
decreases expression |
EXP |
DMSO decreases expression of Gpbar1 protein in rat liver; reaction inhibited by INT-767 |
RGD |
PMID:30038487 |
RGD:15092090 |
NCBI chr 9:81,555,914...81,560,931
Ensembl chr 9:81,559,605...81,560,594
|
|
G |
Gpr75 |
G protein-coupled receptor 75 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of GPR75 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr14:115,270,452...115,278,510
Ensembl chr14:115,275,894...115,278,503
|
|
G |
Grn |
granulin precursor |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of GRN mRNA |
CTD |
PMID:16873554 |
|
NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTA1 protein] |
CTD |
PMID:12370186 |
|
NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
|
|
G |
Gstk1 |
glutathione S-transferase kappa 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of GSTK1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein] |
CTD |
PMID:12370186 |
|
NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
|
|
G |
Gstm2 |
glutathione S-transferase mu 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of GSTM2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
|
|
G |
H3f4 |
H3.4 histone |
multiple interactions decreases methylation |
ISO |
[Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H3-4 protein] Dimethyl Sulfoxide results in decreased methylation of H3-4 protein |
CTD |
PMID:15964820 |
|
NCBI chr10:45,304,696...45,305,106
|
|
G |
H4f16 |
H4 histone 16 |
multiple interactions increases methylation |
ISO |
[Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4-16 protein modified form binds to TGM2 gene]; [Dimethyl Sulfoxide co-treated with Alitretinoin] results in increased methylation of H4-16 protein; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4-16 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4-16 protein]]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide results in increased methylation of H4-16 protein] |
CTD |
PMID:15964820 |
|
NCBI chr17:43,821,122...43,821,587
|
|
G |
H4f3 |
H1.3 linker histone, cluster member |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of H1-3 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
|
|
G |
Hand1 |
heart and neural crest derivatives expressed 1 |
decreases expression increases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of HAND1 mRNA Dimethyl Sulfoxide results in increased expression of HAND1 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr10:43,250,729...43,253,296
Ensembl chr10:43,250,745...43,253,296
|
|
G |
Hbb |
hemoglobin subunit beta |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of HBB mRNA |
CTD |
PMID:21296123 |
|
NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
|
|
G |
Hcar1 |
hydroxycarboxylic acid receptor 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of HCAR1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr12:38,145,177...38,146,232
Ensembl chr12:38,144,855...38,146,271
|
|
G |
Hexim1 |
HEXIM P-TEFb complex subunit 1 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of HEXIM1 mRNA; Dimethyl Sulfoxide results in increased expression of HEXIM1 protein |
CTD |
PMID:16222702 |
|
NCBI chr10:91,200,874...91,202,986
Ensembl chr10:91,200,874...91,202,984
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of HIF1A mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
|
|
G |
Hist1h2ail1 |
histone cluster 1 H2a family member I like 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of H3C6 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183 Ensembl chr17:43,814,773...43,815,183
|
|
G |
Hist1h2bo |
histone cluster 1 H2B family member o |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of H2BC17 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr17:44,756,557...44,758,170
Ensembl chr17:44,756,555...44,793,927
|
|
G |
Hmox1 |
heme oxygenase 1 |
decreases expression multiple interactions increases expression |
ISO EXP |
Dimethyl Sulfoxide results in decreased expression of HMOX1 protein [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA] Dimethyl Sulfoxide results in increased expression of HMOX1 mRNA |
CTD |
PMID:15689417 PMID:22118543 PMID:22193206 PMID:26497626 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hp |
haptoglobin |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of HP mRNA; Dimethyl Sulfoxide results in increased expression of HP protein |
CTD |
PMID:14757319 |
|
NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
|
|
G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
decreases expression |
EXP |
Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA |
CTD |
PMID:12883083 |
|
NCBI chr X:158,196,640...158,228,815
Ensembl chr X:158,197,149...158,228,749
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of HRAS mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
|
|
G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of HSPA1A mRNA |
CTD |
PMID:22193206 |
|
NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein] |
CTD |
PMID:18539414 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
|
|
G |
Ier2 |
immediate early response 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of IER2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
[Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein] |
CTD |
PMID:21878375 PMID:29594315 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Ifngr1 |
interferon gamma receptor 1 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA] |
CTD |
PMID:21878375 |
|
NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
|
|
G |
Ift81 |
intraflagellar transport 81 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of IFT81 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr12:39,420,161...39,507,412
Ensembl chr12:39,423,596...39,506,890
|
|
G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] |
CTD |
PMID:21878375 |
|
NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions decreases expression |
ISO |
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1B mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein] Dimethyl Sulfoxide results in decreased expression of IL1B mRNA |
CTD |
PMID:21878375 PMID:29594315 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il1r1 |
interleukin 1 receptor type 1 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of IL1R1 mRNA |
CTD |
PMID:21878375 |
|
NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
|
|
G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
[Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA |
CTD |
PMID:29594315 |
|
NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
|
|
G |
Il23a |
interleukin 23 subunit alpha |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of IL23A mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
|
|
G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA] |
CTD |
PMID:23751068 |
|
NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
|
|
G |
Il5 |
interleukin 5 |
multiple interactions |
ISO |
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA] |
CTD |
PMID:23751068 |
|
NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
|
|
G |
Il6 |
interleukin 6 |
multiple interactions decreases secretion |
ISO EXP |
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein] Dimethyl Sulfoxide results in decreased secretion of IL6 protein Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA] |
CTD |
PMID:9378980 PMID:10022265 PMID:15689417 PMID:21878375 PMID:24296301 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Irgm |
immunity-related GTPase M |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of IRGM mRNA |
CTD |
PMID:24834073 |
|
NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
|
|
G |
Isg15 |
ISG15 ubiquitin-like modifier |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of ISG15 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
|
|
G |
Itgam |
integrin subunit alpha M |
multiple interactions increases expression |
ISO |
[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of ITGAM protein; Dexamethasone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of ITGAM protein]; Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAM protein] |
CTD |
PMID:7909661 PMID:15964820 PMID:16617325 PMID:22118543 PMID:26330309 |
|
NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
|
|
G |
Itgax |
integrin subunit alpha X |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAX protein] |
CTD |
PMID:15964820 |
|
NCBI chr 1:199,555,560...199,576,948
Ensembl chr 1:199,555,722...199,576,932
|
|
G |
Itgb2 |
integrin subunit beta 2 |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGB2 protein] |
CTD |
PMID:15964820 |
|
NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
EXP ISO |
Dimethyl Sulfoxide results in increased expression of JUN mRNA Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of JUN mRNA] |
CTD |
PMID:7662713 PMID:22193206 |
|
NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
|
|
G |
Klf2 |
Kruppel-like factor 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of KLF2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
|
|
G |
Klf4 |
Kruppel like factor 4 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of KLF4 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
|
|
G |
Klhl41 |
kelch-like family member 41 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of KLHL41 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
|
|
G |
Krt15 |
keratin 15 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of KRT15 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
|
|
G |
Lama1 |
laminin subunit alpha 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of LAMA1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
|
|
G |
Lamb2 |
laminin subunit beta 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of LAMB2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
|
|
G |
Ldhc |
lactate dehydrogenase C |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of LDHC mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:102,914,875...102,931,843
Ensembl chr 1:102,915,191...102,931,839
|
|
G |
Lgals1 |
galectin 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of LGALS1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
|
|
G |
Llgl2 |
LLGL scribble cell polarity complex component 2 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of LLGL2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr10:104,367,826...104,403,726
Ensembl chr10:104,368,247...104,403,724
|
|
G |
LOC103690190 |
histone H2A type 1-E |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of H2AC6 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188 Ensembl chr17:44,747,796...44,748,188
|
|
G |
Lrrc4 |
leucine rich repeat containing 4 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of LRRC4 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:56,110,658...56,114,254
Ensembl chr 4:56,110,658...56,114,254
|
|
G |
Ltc4s |
leukotriene C4 synthase |
multiple interactions |
ISO |
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA] |
CTD |
PMID:23751068 |
|
NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625
|
|
G |
Lyrm9 |
LYR motif containing 9 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of LYRM9 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr10:66,099,478...66,113,559
Ensembl chr10:66,099,531...66,113,559
|
|
G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
increases expression multiple interactions |
ISO |
Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA] |
CTD |
PMID:31265865 |
|
NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
|
|
G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
multiple interactions increases expression |
ISO |
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA] |
CTD |
PMID:31265865 |
|
NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
|
|
G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions decreases activity |
EXP |
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased activity of MAP3K5 protein] Dimethyl Sulfoxide results in decreased activity of MAP3K5 protein |
CTD |
PMID:12370186 |
|
NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
affects expression multiple interactions increases expression |
ISO |
Dimethyl Sulfoxide affects the expression of MAPK3 mRNA cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA] |
CTD |
PMID:24834073 PMID:31265865 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Mat1a |
methionine adenosyltransferase 1A |
increases activity |
ISO |
Dimethyl Sulfoxide results in increased activity of MAT1A protein |
CTD |
PMID:8373829 |
|
NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
|
|
G |
Mat2a |
methionine adenosyltransferase 2A |
increases activity |
ISO |
Dimethyl Sulfoxide results in increased activity of MAT2A protein |
CTD |
PMID:8373829 |
|
NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
|
|
G |
Mc1r |
melanocortin 1 receptor |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of MC1R mRNA |
CTD |
PMID:24834073 |
|
NCBI chr19:56,215,420...56,219,987
|
|
G |
Mef2c |
myocyte enhancer factor 2C |
increases expression decreases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of MEF2C mRNA Dimethyl Sulfoxide results in decreased expression of MEF2C mRNA |
CTD |
PMID:22105179 |
|
NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
|
|
G |
Mettl26 |
methyltransferase like 26 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of METTL26 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr10:15,239,753...15,255,054
Ensembl chr10:15,241,590...15,252,413
|
|
G |
Mfap5 |
microfibril associated protein 5 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of MFAP5 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:155,313,671...155,336,228
Ensembl chr 4:155,313,671...155,336,228
|
|
G |
Mmp1 |
matrix metallopeptidase 1 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of MMP1 mRNA; Dimethyl Sulfoxide results in increased expression of MMP1 protein |
CTD |
PMID:18684396 |
|
NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
EXP |
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein] Dimethyl Sulfoxide results in increased expression of MMP2 protein |
CTD |
PMID:26497626 |
|
NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
EXP |
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Dimethyl Sulfoxide inhibits the reaction [Ethanol results in increased activity of MMP9 protein] Dimethyl Sulfoxide results in increased expression of MMP9 protein |
CTD |
PMID:17603938 PMID:26497626 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
|
|
G |
Mpo |
myeloperoxidase |
increases secretion |
ISO |
Dimethyl Sulfoxide results in increased secretion of MPO protein |
CTD |
PMID:21633126 |
|
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
|
|
G |
Mrpl43 |
mitochondrial ribosomal protein L43 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of MRPL43 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:264,755,537...264,756,404
Ensembl chr 1:264,755,538...264,756,546
|
|
G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein] |
CTD |
PMID:10640773 |
|
NCBI chr 1:214,725,482...214,756,653
|
|
G |
Mug1 |
murinoglobulin 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of PZP mRNA; Dimethyl Sulfoxide results in increased expression of PZP protein |
CTD |
PMID:14757319 |
|
NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
|
|
G |
Mxra8 |
matrix remodeling associated 8 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of MXRA8 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 5:173,288,200...173,292,926
Ensembl chr 5:173,288,447...173,292,929
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of MYC mRNA |
CTD |
PMID:7798212 |
|
NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
|
|
G |
Myo1g |
myosin IG |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of MYO1G mRNA |
CTD |
PMID:22193206 |
|
NCBI chr14:86,781,243...86,796,393
Ensembl chr14:86,781,202...86,796,378
|
|
G |
Nanog |
Nanog homeobox |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of NANOG mRNA |
CTD |
PMID:22105179 |
|
NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
|
|
G |
Nefh |
neurofilament heavy |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of NEFH mRNA |
CTD |
PMID:22105179 |
|
NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
|
|
G |
Nes |
nestin |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of NES mRNA |
CTD |
PMID:22105179 |
|
NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
|
|
G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions decreases expression |
EXP |
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein] Dimethyl Sulfoxide results in decreased expression of NFE2L2 protein |
CTD |
PMID:26497626 |
|
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
|
|
G |
Nfkb2 |
nuclear factor kappa B subunit 2 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA] |
CTD |
PMID:21878375 |
|
NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA] |
CTD |
PMID:21878375 |
|
NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
|
|
G |
Nmi |
N-myc (and STAT) interactor |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of NMI mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:37,458,891...37,480,984
Ensembl chr 3:37,458,890...37,480,984
|
|
G |
Nmrk1 |
nicotinamide riboside kinase 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of NMRK1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
|
|
G |
Nos2 |
nitric oxide synthase 2 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of NOS2 mRNA |
CTD |
PMID:21878375 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Notch3 |
notch receptor 3 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of NOTCH3 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of NQO1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
|
|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
decreases expression |
EXP |
DMSO decreases expression of Nr1h4 mRNA and protein in rat liver; reaction inhibited by INT-767 |
RGD |
PMID:30038487 |
RGD:15092090 |
NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
|
|
G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions |
ISO |
NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] |
CTD |
PMID:20371638 |
|
NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
|
|
G |
Nudt1 |
nudix hydrolase 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of NUDT1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029
|
|
G |
Ocln |
occludin |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of OCLN mRNA |
CTD |
PMID:18661270 |
|
NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
|
|
G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] |
CTD |
PMID:7662713 |
|
NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
|
|
G |
Orm1 |
orosomucoid 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of ORM1 mRNA; Dimethyl Sulfoxide results in increased expression of ORM1 protein |
CTD |
PMID:14757319 |
|
NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
|
|
G |
Ostn |
osteocrin |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of OSTN mRNA |
CTD |
PMID:24834073 |
|
NCBI chr11:76,851,923...76,888,140
Ensembl chr11:76,851,322...76,888,178
|
|
G |
Padi4 |
peptidyl arginine deiminase 4 |
multiple interactions increases expression |
ISO |
Calcimycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of PADI4 protein]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of PADI4 mRNA] |
CTD |
PMID:15964820 PMID:29425503 |
|
NCBI chr 5:159,260,675...159,293,906
Ensembl chr 5:159,260,675...159,293,673
|
|
G |
Pard6a |
par-6 family cell polarity regulator alpha |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of PARD6A mRNA |
CTD |
PMID:24834073 |
|
NCBI chr19:37,668,133...37,670,450
Ensembl chr19:37,668,133...37,672,729
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage |
ISO |
Dimethyl Sulfoxide results in increased cleavage of PARP1 protein |
CTD |
PMID:22535522 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
|
|
G |
Pdcd4 |
programmed cell death 4 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of PDCD4 protein |
CTD |
PMID:17259349 |
|
NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
|
|
G |
Phf6 |
PHD finger protein 6 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of PHF6 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr X:158,698,353...158,739,855
Ensembl chr X:158,698,356...158,739,838 Ensembl chr X:158,698,356...158,739,838
|
|
G |
Pikfyve |
phosphoinositide kinase, FYVE-type zinc finger containing |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of PIKFYVE mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838
|
|
G |
Pjvk |
pejvakin |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of PJVK mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:63,508,386...63,518,163
Ensembl chr 3:63,510,293...63,518,147
|
|
G |
Pla2g2a |
phospholipase A2 group IIA |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of PLA2G2A mRNA |
CTD |
PMID:21878375 |
|
NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
|
|
G |
Plekhf1 |
pleckstrin homology and FYVE domain containing 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of PLEKHF1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:94,609,041...94,616,565
Ensembl chr 1:94,609,377...94,610,854
|
|
G |
Plod2 |
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of PLOD2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
|
|
G |
Pomc |
proopiomelanocortin |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of POMC protein |
CTD |
PMID:15680486 |
|
NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
|
|
G |
Por |
cytochrome p450 oxidoreductase |
multiple interactions decreases activity |
ISO |
Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical] Dimethyl Sulfoxide results in decreased activity of POR protein Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Dimethyl Sulfoxide promotes the reaction [Hemin results in decreased activity of POR protein]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide results in decreased activity of POR protein] |
CTD |
PMID:11368792 PMID:21215309 |
|
NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
|
|
G |
Pot1 |
protection of telomeres 1 |
multiple interactions |
ISO |
2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; [Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA |
CTD |
PMID:26330309 |
|
NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
|
|
G |
Pou5f1 |
POU class 5 homeobox 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of POU5F1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of PPARA mRNA |
CTD |
PMID:21878375 |
|
NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of PPARG mRNA |
CTD |
PMID:21878375 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
|
|
G |
Pqbp1 |
polyglutamine binding protein 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of PQBP1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr X:15,448,570...15,453,130
Ensembl chr X:15,348,138...15,453,130
|
|
G |
Prmt1 |
protein arginine methyltransferase 1 |
multiple interactions |
ISO |
PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]] |
CTD |
PMID:31877331 |
|
NCBI chr 1:100,971,132...100,980,411
Ensembl chr 1:100,971,273...100,980,340
|
|
G |
Prph |
peripherin |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of PRPH mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197
|
|
G |
Ptgds |
prostaglandin D2 synthase |
multiple interactions |
ISO |
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA] |
CTD |
PMID:23751068 |
|
NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
|
|
G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of PTGS1 mRNA |
CTD |
PMID:21878375 |
|
NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO EXP |
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA] [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] Dimethyl Sulfoxide results in increased expression of PTGS2 protein [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein] |
CTD |
PMID:21878375 PMID:23751068 PMID:26497626 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
|
|
G |
Pxdn |
peroxidasin |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of PXDN mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 6:48,866,496...48,982,368
Ensembl chr 6:48,866,601...48,980,340
|
|
G |
Rab3c |
RAB3C, member RAS oncogene family |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of RAB3C mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 2:41,570,955...41,786,681
Ensembl chr 2:41,570,597...41,785,792
|
|
G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions |
ISO |
[cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of RAF1 mRNA |
CTD |
PMID:31265865 |
|
NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
|
|
G |
Reln |
reelin |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of RELN mRNA |
CTD |
PMID:17065238 |
|
NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
|
|
G |
Rfx3 |
regulatory factor X3 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of RFX3 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:245,853,332...246,110,648
Ensembl chr 1:245,859,633...246,110,218
|
|
G |
RGD1309036 |
hypothetical LOC292874 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of C19ORF81 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:100,346,096...100,361,340
Ensembl chr 1:100,346,096...100,359,511
|
|
G |
RGD1309540 |
similar to hypothetical protein MGC40841; similar to hypothetical protein MGC4707 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of C11ORF49 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:80,092,589...80,349,249
Ensembl chr 3:80,095,042...80,349,145
|
|
G |
RGD1309651 |
similar to 1190005I06Rik protein |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of C16ORF74 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr19:54,184,554...54,210,872
Ensembl chr19:54,184,946...54,210,515
|
|
G |
Rnase4 |
ribonuclease A family member 4 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of RNASE4 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389 Ensembl chr15:28,018,040...28,035,389
|
|
G |
Rnf152 |
ring finger protein 152 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of RNF152 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr13:25,183,295...25,262,785
Ensembl chr13:25,186,106...25,262,469
|
|
G |
RT1-Da |
RT1 class II, locus Da |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of HLA-DRA mRNA |
CTD |
PMID:21878375 |
|
NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
|
|
G |
Rxra |
retinoid X receptor alpha |
increases expression affects response to substance |
ISO |
Dimethyl Sulfoxide results in increased expression of RXRA mRNA; Dimethyl Sulfoxide results in increased expression of RXRA protein RXRA protein affects the susceptibility to Dimethyl Sulfoxide |
CTD |
PMID:9751115 |
|
NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
|
|
G |
Rxrg |
retinoid X receptor gamma |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of RXRG protein |
CTD |
PMID:9751115 |
|
NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
|
|
G |
S100a13 |
S100 calcium binding protein A13 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of S100A13 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 2:189,906,022...189,912,516
Ensembl chr 2:189,906,022...189,912,516
|
|
G |
S100a8 |
S100 calcium binding protein A8 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of S100A8 mRNA |
CTD |
PMID:1733233 |
|
NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
|
|
G |
S100a9 |
S100 calcium binding protein A9 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of S100A9 mRNA |
CTD |
PMID:1733233 |
|
NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
|
|
G |
Sdhaf4 |
succinate dehydrogenase complex assembly factor 4 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SDHAF4 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 9:30,243,261...30,251,478
Ensembl chr 9:30,243,610...30,251,388
|
|
G |
Selenbp1 |
selenium binding protein 1 |
increases abundance |
ISO |
SELENBP1 gene mutant form results in increased abundance of Dimethyl Sulfoxide |
CTD |
PMID:29255262 |
|
NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
|
|
G |
Serp2 |
stress-associated endoplasmic reticulum protein family member 2 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SERP2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr15:58,687,784...58,712,023
Ensembl chr15:58,687,786...58,711,872
|
|
G |
Slc24a2 |
solute carrier family 24 member 2 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of SLC24A2 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 5:105,336,287...105,579,959
Ensembl chr 5:105,336,262...105,582,375
|
|
G |
Slc24a4 |
solute carrier family 24 member 4 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of SLC24A4 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 6:126,015,799...126,158,727
Ensembl chr 6:126,018,841...126,153,867
|
|
G |
Slc2a6 |
solute carrier family 2 member 6 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SLC2A6 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136
|
|
G |
Slc35e4 |
solute carrier family 35, member E4 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SLC35E4 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr14:84,163,971...84,170,835
Ensembl chr14:84,163,972...84,170,835
|
|
G |
Snx15 |
sorting nexin 15 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SNX15 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:221,487,058...221,496,200
Ensembl chr 1:221,487,051...221,496,306
|
|
G |
Sod3 |
superoxide dismutase 3 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of SOD3 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
|
|
G |
Sord |
sorbitol dehydrogenase |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of SORD protein] |
CTD |
PMID:17177172 |
|
NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
|
|
G |
Sox17 |
SRY-box transcription factor 17 |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of SOX17 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
|
|
G |
Sp1 |
Sp1 transcription factor |
multiple interactions |
ISO |
Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] |
CTD |
PMID:16675542 |
|
NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
|
|
G |
Spink2 |
serine peptidase inhibitor, Kazal type 2 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SPINK2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr14:33,247,278...33,253,913
Ensembl chr14:33,247,274...33,253,913
|
|
G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression |
EXP |
DMSO increases expression of Srebf1 mRNA in rat liver; reaction inhibited by INT-767 |
RGD |
PMID:30038487 |
RGD:15092090 |
NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
|
|
G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of SRXN1 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
|
|
G |
Stac3 |
SH3 and cysteine rich domain 3 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of STAC3 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
[cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA |
CTD |
PMID:31265865 |
|
NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
|
|
G |
Sult1a1 |
sulfotransferase family 1A member 1 |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] |
CTD |
PMID:14570759 |
|
NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
|
|
G |
Sumo1 |
small ubiquitin-like modifier 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SUMO1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
|
|
G |
Syce2 |
synaptonemal complex central element protein 2 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of SYCE2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr19:25,982,003...26,002,399
Ensembl chr19:25,983,169...26,001,317
|
|
G |
Tas2r103 |
taste receptor, type 2, member 103 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TAS2R14 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 4:167,179,587...167,203,109
Ensembl chr 4:167,179,718...167,180,656
|
|
G |
Tatdn1 |
TatD DNase domain containing 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TATDN1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 7:98,782,164...98,813,001
Ensembl chr 7:98,782,178...98,804,499
|
|
G |
Terc |
telomerase RNA component |
multiple interactions |
ISO |
2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA |
CTD |
PMID:26330309 |
|
NCBI chr 2:116,432,723...116,433,110
Ensembl chr 2:116,432,691...116,433,110
|
|
G |
Terf1 |
telomeric repeat binding factor 1 |
multiple interactions |
ISO |
2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA |
CTD |
PMID:26330309 |
|
NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668
|
|
G |
Terf2 |
telomeric repeat binding factor 2 |
multiple interactions |
ISO |
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dimethyl Sulfoxide co-treated with Tretinoin] results in decreased expression of TERF2 mRNA; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF2 mRNA |
CTD |
PMID:26330309 |
|
NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
|
|
G |
Tert |
telomerase reverse transcriptase |
decreases expression multiple interactions |
ISO |
Dimethyl Sulfoxide results in decreased expression of TERT mRNA 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA |
CTD |
PMID:16180984 PMID:26330309 |
|
NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
|
|
G |
Tf |
transferrin |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of TF mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
|
|
G |
Tfpi |
tissue factor pathway inhibitor |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TFPI mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
|
|
G |
Tgm2 |
transglutaminase 2 |
multiple interactions |
ISO |
[Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4-16 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]] |
CTD |
PMID:15964820 |
|
NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
|
|
G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
multiple interactions |
EXP |
Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] |
CTD |
PMID:11682029 |
|
NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
|
|
G |
Tirap |
TIR domain containing adaptor protein |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TIRAP mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
|
|
G |
Tjp1 |
tight junction protein 1 |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of TJP1 mRNA |
CTD |
PMID:18661270 |
|
NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
|
|
G |
Tmem121 |
transmembrane protein 121 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TMEM121 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 6:137,994,675...138,002,897
Ensembl chr 6:137,997,335...137,998,291
|
|
G |
Tmem134 |
transmembrane protein 134 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TMEM134 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:219,374,005...219,383,365
Ensembl chr 1:219,374,060...219,379,557
|
|
G |
Tmem150c |
transmembrane protein 150C |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TMEM150C mRNA |
CTD |
PMID:24834073 |
|
NCBI chr14:11,094,655...11,166,323
Ensembl chr14:11,095,163...11,166,428
|
|
G |
Tmem266 |
transmembrane protein 266 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TMEM266 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 8:59,952,732...60,014,363
Ensembl chr 8:59,900,651...60,014,363
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO EXP |
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [ferrous sulfate promotes the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]] Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]] |
CTD |
PMID:7539275 PMID:14576080 PMID:21878375 PMID:22319556 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Tnfrsf12a |
TNF receptor superfamily member 12A |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of TNFRSF12A mRNA |
CTD |
PMID:22193206 |
|
NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
|
|
G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions |
ISO |
Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] |
CTD |
PMID:9870925 |
|
NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
|
|
G |
Tomm5 |
translocase of outer mitochondrial membrane 5 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TOMM5 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 5:60,655,708...60,658,568
Ensembl chr 5:60,655,379...60,658,535
|
|
G |
Tpm3 |
tropomyosin 3 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of TPM3 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
|
|
G |
Tra2b |
transformer 2 beta homolog |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of TRA2B mRNA |
CTD |
PMID:22193206 |
|
NCBI chr11:82,373,828...82,392,208
Ensembl chr11:82,373,870...82,392,083
|
|
G |
Trib3 |
tribbles pseudokinase 3 |
increases expression |
EXP |
Dimethyl Sulfoxide results in increased expression of TRIB3 mRNA |
CTD |
PMID:22193206 |
|
NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
|
|
G |
Tsc22d3 |
TSC22 domain family, member 3 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TSC22D3 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr X:111,884,285...111,944,693
Ensembl chr X:111,884,295...111,887,906
|
|
G |
Tsnare1 |
t-SNARE domain containing 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of TSNARE1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 7:115,576,084...115,662,590
|
|
G |
Tubb3 |
tubulin, beta 3 class III |
decreases expression |
ISO |
Dimethyl Sulfoxide results in decreased expression of TUBB3 mRNA |
CTD |
PMID:22105179 |
|
NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
|
|
G |
U2af1l4 |
U2 small nuclear RNA auxiliary factor 1-like 4 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of U2AF1L4 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:89,017,414...89,019,651
Ensembl chr 1:89,017,479...89,019,937
|
|
G |
Ube2c |
ubiquitin-conjugating enzyme E2C |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of UBE2C mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
|
|
G |
Ufsp1 |
UFM1-specific peptidase 1 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of UFSP1 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr12:22,471,141...22,472,357
Ensembl chr12:22,471,391...22,472,044
|
|
G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of UGT1A6 mRNA |
CTD |
PMID:12843640 |
|
NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
|
|
G |
Ugt1a9 |
UDP glucuronosyltransferase family 1 member A9 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of UGT1A9 mRNA |
CTD |
PMID:12843640 |
|
NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
|
|
G |
Upk3b |
uroplakin 3B |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of UPK3B mRNA |
CTD |
PMID:24834073 |
|
NCBI chr12:23,676,169...23,682,395
Ensembl chr12:23,676,152...23,682,381
|
|
G |
Uts2r |
urotensin 2 receptor |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of UTS2R mRNA |
CTD |
PMID:24834073 |
|
NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
|
|
G |
Vom1r10 |
vomeronasal 1 receptor 10 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of VN1R2 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:60,280,451...60,281,386
Ensembl chr 1:60,280,451...60,281,386
|
|
G |
Wapl |
WAPL cohesin release factor |
increases expression |
ISO |
Dimethyl Sulfoxide results in increased expression of WAPL mRNA |
CTD |
PMID:15797623 |
|
NCBI chr16:11,029,325...11,108,867
Ensembl chr16:11,032,531...11,106,589
|
|
G |
Wnt11 |
Wnt family member 11 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of WNT11 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
|
|
G |
Zfp36 |
zinc finger protein 36 |
affects expression |
ISO |
Dimethyl Sulfoxide affects the expression of ZFP36 mRNA |
CTD |
PMID:24834073 |
|
NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
|
|
|
G |
Aco1 |
aconitase 1 |
increases activity decreases activity |
ISO |
ferric ammonium citrate results in increased activity of ACO1 protein ferric ammonium citrate results in decreased activity of ACO1 protein |
CTD |
PMID:11054110 PMID:18073202 |
|
NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
|
|
G |
Aco2 |
aconitase 2 |
multiple interactions increases activity |
ISO |
ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]; ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein] ferric ammonium citrate results in increased activity of ACO2 protein |
CTD |
PMID:16625280 |
|
NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] |
CTD |
PMID:32283200 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
|
|
G |
Alb |
albumin |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of ALB protein] |
CTD |
PMID:24862973 |
|
NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
|
|
G |
Anxa3 |
annexin A3 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein] |
CTD |
PMID:19515424 |
|
NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
|
|
G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein] |
CTD |
PMID:19515424 |
|
NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
|
|
G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions |
ISO |
ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] |
CTD |
PMID:25633564 |
|
NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
|
|
G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
ISO |
ferric ammonium citrate results in increased cleavage of CASP3 protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein] |
CTD |
PMID:17191120 PMID:26318285 PMID:27481217 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] |
CTD |
PMID:12807743 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
ferric ammonium citrate results in decreased expression of COL1A1 mRNA |
CTD |
PMID:19735707 |
|
NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
|
|
G |
Dnm1l |
dynamin 1-like |
multiple interactions decreases phosphorylation |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Cyclosporine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; ferric ammonium citrate results in decreased phosphorylation of and affects the localization of DNM1L protein; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] |
CTD |
PMID:26318285 PMID:27481217 |
|
NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
|
|
G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:32283200 |
|
NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
|
|
G |
Erp29 |
endoplasmic reticulum protein 29 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein] |
CTD |
PMID:19515424 |
|
NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
|
|
G |
F3 |
coagulation factor III, tissue factor |
increases expression multiple interactions |
ISO |
ferric ammonium citrate results in increased expression of F3 mRNA Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA] |
CTD |
PMID:25858758 |
|
NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
|
|
G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein] |
CTD |
PMID:32283200 |
|
NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
|
|
G |
Ftl1 |
ferritin light chain 1 |
multiple interactions increases expression |
ISO |
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of FTL mRNA ferric ammonium citrate results in increased expression of FTL1 mRNA SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA] |
CTD |
PMID:12393473 PMID:19913091 |
|
NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
|
|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein] |
CTD |
PMID:19515424 |
|
NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
|
|
G |
Glo1 |
glyoxalase 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
|
|
G |
Hamp |
hepcidin antimicrobial peptide |
multiple interactions decreases expression |
ISO |
Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] |
CTD |
PMID:25633564 |
|
NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP ISO |
ferric ammonium citrate results in increased expression of HMOX1 protein [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ferric ammonium citrate results in increased expression of HMOX1 protein] |
CTD |
PMID:12393473 PMID:16439612 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein] |
CTD |
PMID:19515424 |
|
NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
|
|
G |
Hspa1l |
heat shock protein family A (Hsp70) member 1 like |
multiple interactions |
ISO |
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA |
CTD |
PMID:12393473 |
|
NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
|
|
G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions |
ISO |
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA |
CTD |
PMID:12393473 |
|
NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
|
|
G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL1B protein] |
CTD |
PMID:24862973 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of IL6 protein] |
CTD |
PMID:24862973 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] |
CTD |
PMID:32283200 |
|
NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
|
|
G |
Ireb2 |
iron responsive element binding protein 2 |
decreases expression decreases activity |
EXP ISO |
ferric ammonium citrate results in decreased expression of IREB2 protein ferric ammonium citrate results in decreased activity of IREB2 protein |
CTD |
PMID:11054110 PMID:17469137 PMID:18073202 |
|
NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
|
|
G |
Lcn2 |
lipocalin 2 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [bathophenanthroline disulfonic acid results in decreased expression of LCN2 protein] |
CTD |
PMID:17350462 |
|
NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK1 protein ferric ammonium citrate results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:17191120 PMID:25858758 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
increases phosphorylation |
ISO |
ferric ammonium citrate results in increased phosphorylation of MAPK14 protein |
CTD |
PMID:17191120 |
|
NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK3 protein ferric ammonium citrate results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:17191120 PMID:25858758 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Mrps9 |
mitochondrial ribosomal protein S9 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] |
CTD |
PMID:19515424 |
|
NCBI chr 9:49,647,257...49,704,828
Ensembl chr 9:49,647,257...49,704,828
|
|
G |
Mt2A |
metallothionein 2A |
multiple interactions |
ISO |
[ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA |
CTD |
PMID:12393473 |
|
NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
|
|
G |
Ncoa4 |
nuclear receptor coactivator 4 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] |
CTD |
PMID:32283200 |
|
NCBI chr16:8,302,950...8,323,294
Ensembl chr16:8,302,950...8,323,293
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA] |
CTD |
PMID:9826428 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Oga |
O-GlcNAcase |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of OGA protein] |
CTD |
PMID:24862973 |
|
NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
|
|
G |
P4ha1 |
prolyl 4-hydroxylase subunit alpha 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
|
|
G |
Pdhb |
pyruvate dehydrogenase E1 subunit beta |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein] |
CTD |
PMID:19515424 |
|
NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
|
|
G |
Pgk1 |
phosphoglycerate kinase 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr X:77,263,399...77,279,373
Ensembl chr X:77,263,359...77,279,367
|
|
G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions |
ISO |
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of PMP22 mRNA |
CTD |
PMID:12393473 |
|
NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
|
|
G |
Ppia |
peptidylprolyl isomerase A |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein] |
CTD |
PMID:19515424 |
|
NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of PTGS2 mRNA] |
CTD |
PMID:24862973 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
|
|
G |
Rack1 |
receptor for activated C kinase 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198 Ensembl chr12:34,149,717...34,155,198
|
|
G |
Slc11a1 |
solute carrier family 11 member 1 |
increases expression |
ISO |
ferric ammonium citrate results in increased expression of SLC11A1 mRNA |
CTD |
PMID:11054110 |
|
NCBI chr 9:81,655,590...81,666,697
Ensembl chr 9:81,655,629...81,666,706
|
|
G |
Slc11a2 |
solute carrier family 11 member 2 |
increases expression |
ISO |
ferric ammonium citrate results in increased expression of SLC11A2 mRNA |
CTD |
PMID:11054110 |
|
NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
|
|
G |
Slc40a1 |
solute carrier family 40 member 1 |
increases expression multiple interactions |
EXP ISO |
ferric ammonium citrate results in increased expression of SLC40A1 mRNA SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA] |
CTD |
PMID:19913091 |
|
NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
|
|
G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of SOD1 mRNA] |
CTD |
PMID:24862973 |
|
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
|
|
G |
Tf |
transferrin |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [TF protein results in increased uptake of Iron] |
CTD |
PMID:11335103 |
|
NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
|
|
G |
Tfr2 |
transferrin receptor 2 |
decreases expression |
ISO |
ferric ammonium citrate results in decreased expression of TFR2 protein |
CTD |
PMID:25633564 |
|
NCBI chr12:22,177,382...22,194,330
Ensembl chr12:22,177,382...22,194,299
|
|
G |
Tfrc |
transferrin receptor |
decreases expression multiple interactions |
ISO |
ferric ammonium citrate results in decreased expression of TFRC mRNA; ferric ammonium citrate results in decreased expression of TFRC protein [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of TFRC mRNA |
CTD |
PMID:11054110 PMID:12393473 PMID:16760464 PMID:18073202 PMID:25633564 |
|
NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of TNF protein] |
CTD |
PMID:24862973 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Tpd52l1 |
TPD52 like 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein] |
CTD |
PMID:19515424 |
|
NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
|
|
G |
Vdac2 |
voltage-dependent anion channel 2 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein] |
CTD |
PMID:19515424 |
|
NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
|
|
G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] |
CTD |
PMID:32283200 |
|
NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
|
|
|
G |
Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
multiple interactions |
ISO |
[CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein; Tranylcypromine inhibits the reaction [[CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein] |
CTD |
PMID:23850985 |
|
NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
|
|
G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
decreases activity |
ISO |
Fluorescein results in decreased activity of KCNH2 protein |
CTD |
PMID:28551711 |
|
NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
|
|
G |
Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions |
ISO |
Fluorescein inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] |
CTD |
PMID:11602689 |
|
NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
|
|
G |
Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
increases uptake multiple interactions |
ISO |
SLCO1B3 protein results in increased uptake of Fluorescein bisphenol A inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; bisphenol F promotes the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; Probenecid inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; tetrabromobisphenol A inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein] |
CTD |
PMID:27989701 |
|
NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
|
|
G |
Slco3a1 |
solute carrier organic anion transporter family, member 3a1 |
increases uptake multiple interactions |
ISO |
SLCO3A1 protein results in increased uptake of Fluorescein Cyclosporine promotes the reaction [SLCO3A1 protein results in increased uptake of Fluorescein]; simvastatin acid affects the reaction [SLCO3A1 protein results in increased uptake of Fluorescein] |
CTD |
PMID:28887287 |
|
NCBI chr 1:135,790,854...136,073,640
Ensembl chr 1:135,790,810...136,073,540
|
|
|
G |
Abcb7 |
ATP binding cassette subfamily B member 7 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ABCB7 protein |
CTD |
PMID:27129696 |
|
NCBI chr X:75,150,511...75,291,950
Ensembl chr X:75,150,608...75,291,938
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of AKR1C2 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
|
|
G |
Anxa4 |
annexin A4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ANXA4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
|
|
G |
Arhgap6 |
Rho GTPase activating protein 6 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ARHGAP6 protein |
CTD |
PMID:27129696 |
|
NCBI chr X:26,314,561...26,845,242
Ensembl chr X:26,315,878...26,376,467
|
|
G |
Azi2 |
5-azacytidine induced 2 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to AZI2 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:126,411,030...126,435,581
Ensembl chr 8:126,411,829...126,434,579
|
|
G |
Capzb |
capping actin protein of muscle Z-line subunit beta |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CAPZB protein |
CTD |
PMID:27129696 |
|
NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
|
|
G |
Cd109 |
CD109 molecule |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CD109 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:85,951,420...86,065,411
Ensembl chr 8:85,951,191...86,065,409
|
|
G |
Cd180 |
CD180 molecule |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CD180 protein |
CTD |
PMID:27129696 |
|
NCBI chr 2:32,820,275...32,833,223
Ensembl chr 2:32,820,322...32,833,125
|
|
G |
Cd86 |
CD86 molecule |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of CD86 protein |
CTD |
PMID:19665512 |
|
NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
|
|
G |
Cd93 |
CD93 molecule |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CD93 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:142,778,798...142,783,774
Ensembl chr 3:142,778,770...142,783,774
|
|
G |
Cdc20 |
cell division cycle 20 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to CDC20 protein |
CTD |
PMID:27129696 |
|
NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
|
|
G |
Copa |
COPI coat complex subunit alpha |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to COPA protein |
CTD |
PMID:27129696 |
|
NCBI chr13:90,467,285...90,508,894
Ensembl chr13:90,467,265...90,508,932
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of CYP1A1 mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
|
|
G |
Dcaf4 |
DDB1 and CUL4 associated factor 4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to DCAF4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 6:107,001,763...107,027,466
Ensembl chr 6:107,001,763...107,027,456
|
|
G |
Dot1l |
DOT1 like histone lysine methyltransferase |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to DOT1L protein |
CTD |
PMID:27129696 |
|
NCBI chr 7:11,786,105...11,824,742
Ensembl chr 7:11,786,105...11,824,742
|
|
G |
Elac1 |
elaC ribonuclease Z 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ELAC1 protein |
CTD |
PMID:27129696 |
|
NCBI chr18:69,706,522...69,723,869
Ensembl chr18:69,706,522...69,723,869
|
|
G |
Enpp7 |
ectonucleotide pyrophosphatase/phosphodiesterase 7 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to ENPP7 protein |
CTD |
PMID:27129696 |
|
NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
|
|
G |
Flrt3 |
fibronectin leucine rich transmembrane protein 3 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to FLRT3 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:134,684,446...134,696,586
Ensembl chr 3:134,683,065...134,696,654
|
|
G |
Fn1 |
fibronectin 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to FN1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of HMOX1 protein [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of HMOX1 protein |
CTD |
PMID:27871981 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to HSPA5 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
|
|
G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to HSPA9 protein |
CTD |
PMID:27129696 |
|
NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
|
|
G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein |
CTD |
PMID:29198882 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IKBKB protein |
CTD |
PMID:27129696 |
|
NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
|
|
G |
Ikzf4 |
IKAROS family zinc finger 4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IKZF4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 7:3,061,422...3,098,142
Ensembl chr 7:3,061,469...3,074,359
|
|
G |
Il17re |
interleukin 17 receptor E |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IL17RE protein |
CTD |
PMID:27129696 |
|
NCBI chr 4:145,413,157...145,426,608
Ensembl chr 4:145,413,230...145,426,603
|
|
G |
Il31ra |
interleukin 31 receptor A |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to IL31RA protein |
CTD |
PMID:27129696 |
|
NCBI chr 2:44,333,347...44,408,005
Ensembl chr 2:44,336,006...44,394,709
|
|
G |
Il4 |
interleukin 4 |
multiple interactions increases expression |
ISO |
[Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; [dibutyrylglycerol analog co-treated with Fluorescein-5-isothiocyanate] affects the secretion of IL4 protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]] |
CTD |
PMID:27871981 PMID:29198882 |
|
NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
|
|
G |
Lypd3 |
Ly6/Plaur domain containing 3 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to LYPD3 protein |
CTD |
PMID:27129696 |
|
NCBI chr 1:81,499,856...81,504,306
Ensembl chr 1:81,499,821...81,504,318
|
|
G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of MAFF mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
|
|
G |
Map3k20 |
mitogen-activated protein kinase kinase kinase 20 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to MAP3K20 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK1 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:27129696 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK3 protein Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:27129696 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:27129696 |
|
NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
ISO |
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein] Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:27129696 |
|
NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
|
|
G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of MT2A mRNA |
CTD |
PMID:20491607 |
|
NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
|
|
G |
Mybpc1 |
myosin binding protein C1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to MYBPC1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 7:29,086,159...29,171,909
Ensembl chr 7:29,086,156...29,171,783
|
|
G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions |
ISO |
[Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of NFE2L2 protein |
CTD |
PMID:27871981 |
|
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of NQO1 mRNA Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]; Melatonin inhibits the reaction [diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]] |
CTD |
PMID:20491607 PMID:27871981 |
|
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
|
|
G |
Plce1 |
phospholipase C, epsilon 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PLCE1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
|
|
G |
Postn |
periostin |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to POSTN protein |
CTD |
PMID:27129696 |
|
NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
|
|
G |
Pprc1 |
PPARG related coactivator 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PPRC1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 1:265,809,892...265,826,319
Ensembl chr 1:265,809,754...265,826,306
|
|
G |
Prkcb |
protein kinase C, beta |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of PRKCB protein |
CTD |
PMID:31958493 |
|
NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
|
|
G |
Psd4 |
pleckstrin and Sec7 domain containing 4 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PSD4 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:1,478,432...1,515,094
Ensembl chr 3:1,478,525...1,514,934
|
|
G |
Psmd14 |
proteasome 26S subunit, non-ATPase 14 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to PSMD14 protein |
CTD |
PMID:27129696 |
|
NCBI chr 3:47,578,449...47,673,330
Ensembl chr 3:47,578,384...47,673,338
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein; Melatonin inhibits the reaction [[diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein] |
CTD |
PMID:27871981 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
Scn5a |
sodium voltage-gated channel alpha subunit 5 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to SCN5A protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
|
|
G |
Skor1 |
SKI family transcriptional corepressor 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to SKOR1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:68,029,930...68,040,504
Ensembl chr 8:68,030,621...68,038,533
|
|
G |
Slc38a10 |
solute carrier family 38, member 10 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to SLC38A10 protein |
CTD |
PMID:27129696 |
|
NCBI chr10:109,284,054...109,333,907
Ensembl chr10:109,284,957...109,333,899
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases phosphorylation |
ISO |
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:27871981 |
|
NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
|
|
G |
Stat5a |
signal transducer and activator of transcription 5A |
multiple interactions increases phosphorylation |
ISO |
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]] |
CTD |
PMID:27871981 |
|
NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
|
|
G |
Stat6 |
signal transducer and activator of transcription 6 |
increases phosphorylation multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]] |
CTD |
PMID:27871981 |
|
NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
|
|
G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to TRPA1 protein |
CTD |
PMID:27129696 |
|
NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
|
|
G |
Tslp |
thymic stromal lymphopoietin |
increases expression multiple interactions |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of TSLP protein diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]] |
CTD |
PMID:27871981 |
|
NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
|
|
G |
Txn1 |
thioredoxin 1 |
increases expression |
ISO |
Fluorescein-5-isothiocyanate results in increased expression of TXN mRNA |
CTD |
PMID:20491607 |
|
NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
|
|
G |
Usp3 |
ubiquitin specific peptidase 3 |
affects binding |
ISO |
Fluorescein-5-isothiocyanate binds to USP3 protein |
CTD |
PMID:27129696 |
|
NCBI chr 8:72,207,970...72,284,871
Ensembl chr 8:72,207,972...72,284,873
|
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
ISO |
gadodiamide results in increased phosphorylation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:19561517 |
|
NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
|
|
G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
increases expression |
ISO |
gadodiamide results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
|
|
G |
Ankrd22 |
ankyrin repeat domain 22 |
increases expression |
ISO |
gadodiamide results in increased expression of ANKRD22 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 1:252,430,750...252,461,346
Ensembl chr 1:252,429,677...252,461,461
|
|
G |
Atm |
ATM serine/threonine kinase |
increases expression |
ISO |
gadodiamide results in increased expression of ATM mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
|
|
G |
Atp8b1 |
ATPase phospholipid transporting 8B1 |
increases expression |
ISO |
gadodiamide results in increased expression of ATP8B1 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression increases secretion |
ISO EXP |
gadodiamide results in increased expression of CCL2 mRNA gadodiamide results in increased expression of CCL2 mRNA; gadodiamide results in increased expression of CCL2 protein gadodiamide results in increased secretion of CCL2 protein |
CTD |
PMID:20938346 PMID:20959327 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
|
|
G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
EXP |
gadodiamide results in increased expression of CCL4 protein |
CTD |
PMID:20938346 |
|
NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
|
|
G |
Ccl7 |
C-C motif chemokine ligand 7 |
increases expression |
EXP |
gadodiamide results in increased expression of CCL7 protein |
CTD |
PMID:20938346 |
|
NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
|
|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression increases secretion |
ISO EXP |
gadodiamide results in increased expression of CXCL10 mRNA gadodiamide results in increased expression of CXCL10 protein gadodiamide results in increased secretion of CXCL10 protein |
CTD |
PMID:20938346 PMID:20959327 |
|
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
|
|
G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
increases secretion increases expression |
ISO |
gadodiamide results in increased secretion of CXCL11 protein gadodiamide results in increased expression of CXCL11 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
|
|
G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
gadodiamide results in increased expression of CXCL12 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
|
|
G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
gadodiamide results in increased expression of CXCL9 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
|
|
G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
increases expression |
ISO |
gadodiamide results in increased expression of IDO1 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
|
|
G |
Ifi44l |
interferon-induced protein 44-like |
increases expression |
ISO |
gadodiamide results in increased expression of IFI44L mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
|
|
G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
increases expression |
ISO |
gadodiamide results in increased expression of IFIT3 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
|
|
G |
Ifng |
interferon gamma |
increases expression |
ISO |
gadodiamide results in increased expression of IFNG mRNA; gadodiamide results in increased expression of IFNG protein |
CTD |
PMID:19404939 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
|
|
G |
Il13 |
interleukin 13 |
increases expression |
ISO |
gadodiamide results in increased expression of IL13 mRNA; gadodiamide results in increased expression of IL13 protein |
CTD |
PMID:19404939 |
|
NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
|
|
G |
Il1a |
interleukin 1 alpha |
increases expression |
EXP |
gadodiamide results in increased expression of IL1A protein |
CTD |
PMID:20938346 |
|
NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
|
|
G |
Il4 |
interleukin 4 |
increases expression affects expression |
ISO |
gadodiamide results in increased expression of IL4 protein gadodiamide affects the expression of IL4 mRNA |
CTD |
PMID:19404939 |
|
NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
|
|
G |
Il4i1 |
interleukin 4 induced 1 |
increases expression |
ISO |
gadodiamide results in increased expression of IL4I1 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 1:100,811,727...100,836,901
Ensembl chr 1:100,830,064...100,836,677
|
|
G |
Il6 |
interleukin 6 |
affects expression increases expression |
ISO |
gadodiamide affects the expression of IL6 protein gadodiamide results in increased expression of IL6 mRNA |
CTD |
PMID:19404939 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Kitlg |
KIT ligand |
increases expression |
EXP |
gadodiamide results in increased expression of KITLG protein |
CTD |
PMID:20938346 |
|
NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:19561517 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:19561517 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions increases expression |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein] gadodiamide results in increased expression of MMP1 mRNA; gadodiamide results in increased expression of MMP1 protein |
CTD |
PMID:19561517 |
|
NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
|
|
G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
ISO |
gadodiamide results in increased expression of NOS2 protein |
CTD |
PMID:20959327 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Nxpe3 |
neurexophilin and PC-esterase domain family, member 3 |
increases expression |
ISO |
gadodiamide results in increased expression of NXPE3 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr11:47,188,332...47,238,372
Ensembl chr11:47,188,495...47,238,372
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases localization |
ISO |
gadodiamide results in increased localization of RELA protein |
CTD |
PMID:20959327 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
RGD1306063 |
similar to HT021 |
increases expression |
ISO |
gadodiamide results in increased expression of C3ORF14 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
|
|
G |
Rhoq |
ras homolog family member Q |
increases expression |
ISO |
gadodiamide results in increased expression of RHOQ mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
|
|
G |
Rit1 |
Ras-like without CAAX 1 |
increases expression |
ISO |
gadodiamide results in increased expression of RIT1 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
|
|
G |
Rnf125 |
ring finger protein 125 |
increases expression |
ISO |
gadodiamide results in increased expression of RNF125 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr18:15,193,226...15,225,454
Ensembl chr18:15,192,962...15,225,427
|
|
G |
Rsad2 |
radical S-adenosyl methionine domain containing 2 |
increases expression |
ISO |
gadodiamide results in increased expression of RSAD2 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
|
|
G |
Slc39a10 |
solute carrier family 39 member 10 |
increases expression |
ISO |
gadodiamide results in increased expression of SLC39A10 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
|
|
G |
Spn |
sialophorin |
increases expression |
ISO |
gadodiamide results in increased expression of SPN mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 1:198,572,999...198,585,664
Ensembl chr 1:198,572,999...198,577,226
|
|
G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
EXP |
gadodiamide results in increased expression of SPP1 protein |
CTD |
PMID:20938346 |
|
NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression |
ISO EXP |
gadodiamide results in increased expression of TGFB1 mRNA; gadodiamide results in increased expression of TGFB1 protein |
CTD |
PMID:19404939 PMID:20938346 |
|
NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression multiple interactions |
ISO EXP |
gadodiamide results in increased expression of TIMP1 mRNA; gadodiamide results in increased expression of TIMP1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein] |
CTD |
PMID:19561517 PMID:20938346 |
|
NCBI chr X:1,364,771...1,369,451
Ensembl chr X:1,364,786...1,369,384
|
|
G |
Ubd |
ubiquitin D |
increases expression |
ISO |
gadodiamide results in increased expression of UBD mRNA |
CTD |
PMID:20959327 |
|
NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
|
|
G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO EXP |
gadodiamide results in increased expression of VEGFA mRNA; gadodiamide results in increased expression of VEGFA protein |
CTD |
PMID:19404939 PMID:20938346 |
|
NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
|
|
G |
Wdr5 |
WD repeat domain 5 |
increases expression |
ISO |
gadodiamide results in increased expression of WDR5 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr 3:6,061,892...6,080,724
Ensembl chr 3:6,061,940...6,080,680
|
|
G |
Xiap |
X-linked inhibitor of apoptosis |
increases expression |
ISO |
gadodiamide results in increased expression of XIAP mRNA |
CTD |
PMID:20959327 |
|
NCBI chr X:128,409,425...128,455,786
Ensembl chr X:128,409,472...128,453,000
|
|
G |
Zfp652 |
zinc finger protein 652 |
increases expression |
ISO |
gadodiamide results in increased expression of ZNF652 mRNA |
CTD |
PMID:20959327 |
|
NCBI chr10:83,556,809...83,572,014
Ensembl chr10:83,556,809...83,572,019
|
|
|
G |
Edn1 |
endothelin 1 |
increases expression |
EXP |
iodixanol results in increased expression of EDN1 protein |
CTD |
PMID:21354280 |
|
NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA |
CTD |
PMID:29860548 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
EXP |
iodixanol results in increased expression of HAVCR1 mRNA |
CTD |
PMID:19104440 |
|
NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
|
|
G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMGB1 protein |
CTD |
PMID:29860548 |
|
NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP |
iodixanol results in increased expression of HMOX1 mRNA [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMOX1 mRNA |
CTD |
PMID:19104440 PMID:29860548 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Nos2 |
nitric oxide synthase 2 |
decreases expression |
EXP |
iodixanol results in decreased expression of NOS2 protein |
CTD |
PMID:21354280 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PINK1 protein |
CTD |
PMID:29860548 |
|
NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
|
|
G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein |
CTD |
PMID:29860548 |
|
NCBI chr 1:48,880,015...50,069,998
|
|
G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
EXP |
iodixanol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein] |
CTD |
PMID:29860548 |
|
NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
|
|
|
G |
Agt |
angiotensinogen |
increases expression multiple interactions |
EXP |
Iohexol results in increased expression of AGT protein telmisartan inhibits the reaction [Iohexol results in increased expression of AGT protein] |
CTD |
PMID:19452295 |
|
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
|
|
G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
Iohexol results in increased expression of BAK1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Iohexol results in increased expression of BAX mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
Iohexol results in increased expression of BBC3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 1:78,261,491...78,267,802
|
|
G |
Casp3 |
caspase 3 |
multiple interactions increases activity |
EXP |
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]]; Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]; Telmisartan inhibits the reaction [Iohexol results in increased activity of CASP3 protein] |
CTD |
PMID:19452295 PMID:26562095 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Casp9 |
caspase 9 |
increases expression |
ISO |
Iohexol results in increased expression of CASP9 mRNA; Iohexol results in increased expression of CASP9 protein |
CTD |
PMID:29705293 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Eng |
endoglin |
decreases expression |
ISO |
Iohexol results in decreased expression of ENG protein |
CTD |
PMID:29705293 |
|
NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
|
|
G |
Fabp3 |
fatty acid binding protein 3 |
increases expression |
ISO |
Iohexol results in increased expression of FABP3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA |
CTD |
PMID:29860548 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
|
|
G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMGB1 protein |
CTD |
PMID:29860548 |
|
NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
Iohexol results in increased expression of HMOX1 mRNA [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMOX1 mRNA |
CTD |
PMID:29705293 PMID:29860548 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Ifi44 |
interferon-induced protein 44 |
decreases expression |
ISO |
Iohexol results in decreased expression of IFI44 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
|
|
G |
Ifih1 |
interferon induced with helicase C domain 1 |
decreases expression |
ISO |
Iohexol results in decreased expression of IFIH1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of IL1B mRNA]]; Iohexol promotes the reaction [Glycerol results in increased expression of IL1B mRNA] |
CTD |
PMID:26562095 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
increases expression |
ISO |
Iohexol results in increased expression of MAP3K1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
increases expression |
ISO |
Iohexol results in increased expression of MAPK14 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of NLRP3 protein |
CTD |
PMID:29860548 |
|
NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
EXP |
[Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of NQO1 mRNA |
CTD |
PMID:29860548 |
|
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
|
|
G |
Oas3 |
2'-5'-oligoadenylate synthetase 3 |
decreases expression |
ISO |
Iohexol results in decreased expression of OAS3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr12:41,313,081...41,368,217
Ensembl chr12:41,316,764...41,336,562
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression |
ISO |
Iohexol results in increased expression of PPARG mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases expression |
ISO |
Iohexol results in increased expression of RELA mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
Rsad2 |
radical S-adenosyl methionine domain containing 2 |
decreases expression |
ISO |
Iohexol results in decreased expression of RSAD2 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
|
|
G |
S100a4 |
S100 calcium-binding protein A4 |
increases expression |
ISO |
Iohexol results in increased expression of S100A4 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
|
|
G |
Sox9 |
SRY-box transcription factor 9 |
increases expression |
ISO |
Iohexol results in increased expression of SOX9 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
|
|
G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
EXP |
Iohexol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein] |
CTD |
PMID:29860548 |
|
NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TGFB1 mRNA]]; Iohexol promotes the reaction [Glycerol results in increased expression of TGFB1 mRNA] |
CTD |
PMID:26562095 |
|
NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
|
|
G |
Thy1 |
Thy-1 cell surface antigen |
decreases expression |
ISO |
Iohexol results in decreased expression of THY1 protein |
CTD |
PMID:29705293 |
|
NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF mRNA]]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF protein]]; Iohexol promotes the reaction [Glycerol results in increased expression of TNF mRNA]; Iohexol promotes the reaction [Glycerol results in increased expression of TNF protein] |
CTD |
PMID:26562095 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
Iohexol results in increased expression of TP53 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
|
|
G |
Tubb3 |
tubulin, beta 3 class III |
increases expression |
ISO |
Iohexol results in increased expression of TUBB3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
|
|
G |
Usp18 |
ubiquitin specific peptidase 18 |
decreases expression |
ISO |
Iohexol results in decreased expression of USP18 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
|
|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] |
CTD |
PMID:26474837 |
|
NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
|
|
G |
Lcn2 |
lipocalin 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] |
CTD |
PMID:26474837 |
|
NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
iomeprol results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:21036957 |
|
NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
increases phosphorylation |
ISO |
iomeprol results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:21036957 |
|
NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
|
|
G |
Pim1 |
Pim-1 proto-oncogene, serine/threonine kinase |
affects expression |
ISO |
iomeprol affects the expression of PIM1 protein |
CTD |
PMID:21036957 |
|
NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases phosphorylation |
ISO |
iomeprol results in increased phosphorylation of RELA protein |
CTD |
PMID:21036957 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
affects expression |
ISO |
iomeprol affects the expression of STAT3 protein modified form |
CTD |
PMID:21036957 |
|
NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
|
|
|
G |
Ren |
renin |
multiple interactions increases expression |
EXP |
Acetylcysteine inhibits the reaction [ioxitalamic acid results in increased expression of REN protein]; Propranolol inhibits the reaction [ioxitalamic acid results in increased expression of REN protein] |
CTD |
PMID:19945959 |
|
NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
|
|
|
G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
Iopamidol results in increased expression of BAK1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Iopamidol results in increased expression of BAX mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
Iopamidol results in increased expression of BBC3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 1:78,261,491...78,267,802
|
|
G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
ISO |
Iopamidol results in increased expression of and results in increased cleavage of CASP9 protein Iopamidol results in increased expression of CASP9 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
|
|
G |
Cryab |
crystallin, alpha B |
increases expression |
ISO |
Iopamidol results in increased expression of CRYAB mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
|
|
G |
Eng |
endoglin |
decreases expression |
ISO |
Iopamidol results in decreased expression of ENG protein |
CTD |
PMID:29705293 |
|
NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
|
|
G |
Fabp3 |
fatty acid binding protein 3 |
increases expression |
ISO |
Iopamidol results in increased expression of FABP3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
|
|
G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO |
Iopamidol results in increased expression of FABP4 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
|
|
G |
Ifi44 |
interferon-induced protein 44 |
decreases expression |
ISO |
Iopamidol results in decreased expression of IFI44 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
|
|
G |
Ifih1 |
interferon induced with helicase C domain 1 |
decreases expression |
ISO |
Iopamidol results in decreased expression of IFIH1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
|
|
G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
increases expression |
ISO |
Iopamidol results in increased expression of MAP3K1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
increases expression |
ISO |
Iopamidol results in increased expression of MAPK14 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
|
|
G |
Mx2 |
MX dynamin like GTPase 2 |
decreases expression |
ISO |
Iopamidol results in decreased expression of MX1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
|
|
G |
Oas3 |
2'-5'-oligoadenylate synthetase 3 |
decreases expression |
ISO |
Iopamidol results in decreased expression of OAS3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr12:41,313,081...41,368,217
Ensembl chr12:41,316,764...41,336,562
|
|
G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Iopamidol results in increased expression of PMAIP1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases expression |
ISO |
Iopamidol results in increased expression of RELA mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
|
|
G |
Rsad2 |
radical S-adenosyl methionine domain containing 2 |
decreases expression |
ISO |
Iopamidol results in decreased expression of RSAD2 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
|
|
G |
S100a4 |
S100 calcium-binding protein A4 |
increases expression |
ISO |
Iopamidol results in increased expression of S100A4 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
|
|
G |
Sox9 |
SRY-box transcription factor 9 |
increases expression |
ISO |
Iopamidol results in increased expression of SOX9 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
decreases expression |
ISO |
Iopamidol results in decreased expression of STAT1 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
|
|
G |
Thy1 |
Thy-1 cell surface antigen |
decreases expression |
ISO |
Iopamidol results in decreased expression of THY1 protein |
CTD |
PMID:29705293 |
|
NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
|
|
G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
Iopamidol results in increased expression of TP53 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
|
|
G |
Tubb3 |
tubulin, beta 3 class III |
increases expression |
ISO |
Iopamidol results in increased expression of TUBB3 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
|
|
G |
Usp18 |
ubiquitin specific peptidase 18 |
decreases expression |
ISO |
Iopamidol results in decreased expression of USP18 mRNA |
CTD |
PMID:29705293 |
|
NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
|
|
|
G |
Edn1 |
endothelin 1 |
increases expression |
EXP |
iopromide results in increased expression of EDN1 protein |
CTD |
PMID:21354280 |
|
NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
|
|
G |
Mr1 |
major histocompatibility complex, class I-related |
affects expression |
ISO |
iopromide affects the expression of MR1 mRNA |
CTD |
PMID:25811541 |
|
NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
|
|
G |
Nos2 |
nitric oxide synthase 2 |
decreases expression |
EXP |
iopromide results in decreased expression of NOS2 protein |
CTD |
PMID:21354280 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
|
|
G |
RT1-Da |
RT1 class II, locus Da |
affects expression |
ISO |
iopromide affects the expression of HLA-DRA mRNA |
CTD |
PMID:25811541 |
|
NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
|
|
|
G |
F2 |
coagulation factor II |
multiple interactions |
ISO |
Ioxaglic Acid inhibits the reaction [F2 protein binds to SERPINC1 protein] |
CTD |
PMID:2020943 |
|
NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
|
|
G |
Serpinc1 |
serpin family C member 1 |
multiple interactions |
ISO |
Ioxaglic Acid inhibits the reaction [F2 protein binds to SERPINC1 protein] |
CTD |
PMID:2020943 |
|
NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
|
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Diatrizoate Meglumine results in increased expression of BAX protein |
CTD |
PMID:17173243 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression multiple interactions |
ISO EXP |
Diatrizoate Meglumine results in increased expression of BCL2 protein Diatrizoate Meglumine results in decreased expression of BCL2 mRNA Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in decreased expression of BCL2 mRNA] |
CTD |
PMID:17173243 PMID:28412091 |
|
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
|
|
G |
Casp12 |
caspase 12 |
increases cleavage |
EXP |
Diatrizoate Meglumine results in increased cleavage of CASP12 protein |
CTD |
PMID:20071420 |
|
NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
|
|
G |
Casp3 |
caspase 3 |
increases activity increases expression multiple interactions |
ISO EXP |
Diatrizoate Meglumine results in increased activity of CASP3 protein Diatrizoate Meglumine results in increased expression of CASP3 mRNA [Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein; [sulforafan co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein]; Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of CASP3 mRNA]; NFE2L2 protein affects the reaction [[sulforafan co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein] |
CTD |
PMID:17173243 PMID:23335628 PMID:28412091 PMID:31173751 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
|
|
G |
Ctf1 |
cardiotrophin 1 |
multiple interactions |
EXP |
CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein]; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein]; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein] |
CTD |
PMID:23335628 |
|
NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
|
|
G |
Eif2a |
eukaryotic translation initiation factor 2A |
increases phosphorylation |
EXP |
Diatrizoate Meglumine results in increased phosphorylation of EIF2A protein |
CTD |
PMID:20071420 |
|
NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
|
|
G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
increases phosphorylation |
EXP |
Diatrizoate Meglumine results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:20071420 |
|
NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
|
|
G |
Gsta2 |
glutathione S-transferase alpha 2 |
increases expression |
EXP |
Diatrizoate Meglumine results in increased expression of GSTA2 mRNA |
CTD |
PMID:28412091 |
|
NCBI chr 8:85,640,081...85,645,621
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein] |
CTD |
PMID:23335628 |
|
NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression decreases expression multiple interactions |
EXP |
Diatrizoate Meglumine results in increased expression of HMOX1 mRNA Diatrizoate Meglumine results in decreased expression of HMOX1 protein Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of HMOX1 mRNA] |
CTD |
PMID:28412091 PMID:31173751 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
Diatrizoate Meglumine results in increased expression of HSP90B1 protein |
CTD |
PMID:20071420 |
|
NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Diatrizoate Meglumine results in increased expression of HSPA5 protein |
CTD |
PMID:20071420 |
|
NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
|
|
G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
EXP |
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [sulforafan inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]]; sulforafan inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein] Diatrizoate Meglumine results in increased expression of IL6 mRNA; Diatrizoate Meglumine results in increased expression of IL6 protein |
CTD |
PMID:28412091 PMID:31173751 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions decreases expression increases expression |
EXP |
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of NFE2L2 mRNA]; NFE2L2 protein affects the reaction [[sulforafan co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein]; NFE2L2 protein affects the reaction [sulforafan inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]] Diatrizoate Meglumine results in decreased expression of NFE2L2 protein |
CTD |
PMID:28412091 PMID:31173751 |
|
NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
|
|
G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
EXP |
[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein] |
CTD |
PMID:23335628 |
|
NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
|
|
G |
Tp53 |
tumor protein p53 |
increases expression multiple interactions |
EXP |
Diatrizoate Meglumine results in increased expression of TP53 mRNA Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA] |
CTD |
PMID:28412091 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
|
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases expression |
ISO |
perflubron results in increased expression of CYP11A1 mRNA |
CTD |
PMID:25871633 |
|
NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
|
|
G |
Cyp11b2 |
cytochrome P450, family 11, subfamily b, polypeptide 2 |
increases expression |
ISO |
perflubron results in increased expression of CYP11B1 mRNA |
CTD |
PMID:25871633 |
|
NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
|
|
G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
increases expression |
ISO |
perflubron results in increased expression of CYP11B2 mRNA |
CTD |
PMID:25871633 |
|
NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
increases expression |
ISO |
perflubron results in increased expression of CYP17A1 mRNA |
CTD |
PMID:25871633 |
|
NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
|
|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
increases expression |
ISO |
perflubron results in increased expression of CYP19A1 mRNA |
CTD |
PMID:25871633 |
|
NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
perflubron results in increased expression of HMGCR mRNA |
CTD |
PMID:25871633 |
|
NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
|
|
G |
Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
increases expression |
ISO |
perflubron results in increased expression of HSD17B1 mRNA |
CTD |
PMID:25871633 |
|
NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
|
|
G |
Hsd3b2 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
increases expression |
ISO |
perflubron results in increased expression of HSD3B2 mRNA |
CTD |
PMID:25871633 |
|
NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
|
|
G |
Star |
steroidogenic acute regulatory protein |
increases expression |
ISO |
perflubron results in increased expression of STAR mRNA |
CTD |
PMID:25871633 |
|
NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
|
|
|
G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
EXP |
perfluorobutane results in increased expression of ACOT1 mRNA |
CTD |
PMID:19407336 |
|
NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
|
|
G |
Angptl4 |
angiopoietin-like 4 |
increases expression |
ISO |
perfluorobutane results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
|
|
G |
Apoa2 |
apolipoprotein A2 |
affects expression |
ISO |
perfluorobutane affects the expression of APOA2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
|
|
G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
perfluorobutane results in decreased expression of CCND1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
|
|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
ISO |
perfluorobutane results in increased expression of CPT1A mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:218,568,157...218,629,679 | |