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Gene: Tfpi (tissue factor pathway inhibitor) Mus musculus
Symbol: Tfpi
Name: tissue factor pathway inhibitor
RGD ID: 62207
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of blood coagulation. Localizes to extracellular space. Is expressed in several structures, including central nervous system; hemolymphoid system; liver; lung; and retina. Human ortholog(s) of this gene implicated in several diseases, including factor VIII deficiency; osteonecrosis; thrombophilia (multiple); toxic shock syndrome; and transient cerebral ischemia. Orthologous to human TFPI (tissue factor pathway inhibitor); PARTICIPATES IN coagulation cascade pathway; syndecan signaling pathway; complement system pathway; INTERACTS WITH 1,2-dichloroethane; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A630013F22Rik; AW552122; EPI; extrinsic pathway inhibitor; LACI; lipoprotein-associated coagulation inhibitor
Homo sapiens (human) : TFPI (tissue factor pathway inhibitor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfpi (tissue factor pathway inhibitor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfpi (tissue factor pathway inhibitor)
Pan paniscus (bonobo/pygmy chimpanzee) : TFPI (tissue factor pathway inhibitor)
Canis lupus familiaris (dog) : TFPI (tissue factor pathway inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfpi (tissue factor pathway inhibitor)
Sus scrofa (pig) : TFPI (tissue factor pathway inhibitor)
Chlorocebus sabaeus (African green monkey) : TFPI (tissue factor pathway inhibitor)
Heterocephalus glaber (naked mole-rat) : Tfpi (tissue factor pathway inhibitor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl284,432,855 - 84,476,775 (-)EnsemblGRCm38mm10GRCm38
GRCm38284,432,855 - 84,476,775 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37284,273,017 - 84,316,932 (-)NCBIGRCm37mm9NCBIm37
MGSCv36284,233,699 - 84,275,013 (-)NCBImm8
Celera286,041,007 - 86,084,914 (-)NCBICelera
Cytogenetic Map2DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tfpi
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62207
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.