Tfpi (tissue factor pathway inhibitor) - Rat Genome Database

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Gene: Tfpi (tissue factor pathway inhibitor) Mus musculus
Analyze
Symbol: Tfpi
Name: tissue factor pathway inhibitor
RGD ID: 62207
MGI Page MGI
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of blood coagulation. Predicted to act upstream of or within blood coagulation and negative regulation of peptidase activity. Located in extracellular space. Is expressed in several structures, including central nervous system; hemolymphoid system; liver; lung; and retina. Human ortholog(s) of this gene implicated in several diseases, including factor VIII deficiency; osteonecrosis; thrombophilia (multiple); toxic shock syndrome; and transient cerebral ischemia. Orthologous to human TFPI (tissue factor pathway inhibitor); PARTICIPATES IN coagulation cascade pathway; syndecan signaling pathway; complement system pathway; INTERACTS WITH 1,2-dichloroethane; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A630013F22Rik; AW552122; EPI; extrinsic pathway inhibitor; LACI; lipoprotein-associated coagulation inhibitor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,263,199 - 84,307,119 (-)NCBIGRCm39mm39
GRCm39 Ensembl284,263,199 - 84,307,119 (-)Ensembl
GRCm38284,432,855 - 84,476,775 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,432,855 - 84,476,775 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,273,017 - 84,316,932 (-)NCBIGRCm37mm9NCBIm37
MGSCv36284,233,699 - 84,275,013 (-)NCBImm8
Celera286,041,007 - 86,084,914 (-)NCBICelera
Cytogenetic Map2DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
belinostat  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
busulfan  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
carbon nanotube  (EXP)
carvedilol  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (ISO)
clomiphene  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dimethyl sulfoxide  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
estrone  (ISO)
ethanol  (ISO)
etoposide  (ISO)
fluvastatin  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
glucose  (ISO)
hexestrol  (ISO)
indole-3-methanol  (ISO)
irbesartan  (ISO)
irinotecan  (ISO)
isobutanol  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
medroxyprogesterone acetate  (ISO)
mercury dibromide  (ISO)
mestranol  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PD 0325901  (ISO)
pentanal  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Bombeli T, etal., Thromb Haemost. 2004 Jan;91(1):80-6.
2. Bregengard C, etal., Blood Coagul Fibrinolysis. 1993 Oct;4(5):699-706.
3. Castoldi E, etal., J Thromb Haemost. 2010 Feb;8(2):294-300. doi: 10.1111/j.1538-7836.2009.03712.x. Epub 2009 Nov 30.
4. Choi G, etal., Eur Respir J. 2007 Sep;30(3):423-8. Epub 2007 May 30.
5. Dahm A, etal., Blood. 2003 Jun 1;101(11):4387-92. Epub 2003 Jan 30.
6. Dai XL, etal., Mol Cells. 2008 Nov 30;26(5):490-5.
7. Duckers C, etal., Blood. 2008 Nov 1;112(9):3615-23. doi: 10.1182/blood-2008-06-162453. Epub 2008 Aug 11.
8. Duering C, etal., Thromb Haemost. 2004 Oct;92(4):707-12.
9. Elsayed YA, etal., Am J Clin Pathol. 1996 Nov;106(5):574-83.
10. Enkhbaatar P, etal., Thromb Haemost. 2001 Dec;86(6):1573-7.
11. Erez O, etal., J Matern Fetal Neonatal Med. 2008 Oct;21(10):732-44. doi: 10.1080/14767050802361807.
12. Ertenli I, etal., Ann Rheum Dis. 2001 Dec;60(12):1149-51.
13. Farid FA, etal., SAJCH. 2011 Dec;5(4):107-111.
14. Fujii M, etal., Thromb Res. 2000 Jul 15;99(2):111-7.
15. Golino P, etal., Circulation. 2003 Dec 9;108(23):2864-9. Epub 2003 Dec 1.
16. Han X, etal., Arterioscler Thromb Vasc Biol. 1999 Oct;19(10):2563-7.
17. Hao J, etal., J Huazhong Univ Sci Technolog Med Sci. 2009 Dec;29(6):697-700. doi: 10.1007/s11596-009-0604-4. Epub 2009 Dec 29.
18. Hara S, etal., Lab Invest. 1997 Dec;77(6):581-9.
19. Hoke M, etal., Thromb Haemost. 2005 Oct;94(4):787-90.
20. Huang ZF, etal., Blood. 1997 Aug 1;90(3):944-51.
21. Iversen N, etal., Thromb Res. 2002 Jan 1;105(1):33-6.
22. Kijiyama N, etal., Biochem Biophys Res Commun. 2006 Jan 27;339(4):1113-9. Epub 2005 Dec 5.
23. Kobayashi M, etal., Thromb Haemost. 1995 Jan;73(1):10-4.
24. Maroney SA, etal., J Thromb Haemost. 2008 Jan;6(1):111-7. Epub 2007 Oct 25.
25. Maroney SA, etal., Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3927-31. doi: 10.1073/pnas.1119858109. Epub 2012 Feb 21.
26. MGD and Homologene mouse data transfer
27. MGD data from the GO Consortium
28. MGD IEA
29. Mochida S, etal., Hepatology. 1999 May;29(5):1532-40.
30. Mukai Y and Sato S, Pregnancy Hypertens. 2012 Jan;2(1):53-8. doi: 10.1016/j.preghy.2011.10.002. Epub 2011 Oct 21.
31. Niiro M, etal., Thromb Res. 2008;122(2):247-55. Epub 2007 Dec 11.
32. Norris LA, Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):369-83.
33. Ogiwara K, etal., Int J Hematol. 2014;99(5):577-87. doi: 10.1007/s12185-014-1572-4. Epub 2014 Apr 1.
34. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
35. Okugawa Y, etal., Am J Hematol. 2000 Nov;65(3):210-4.
36. Ong K, etal., Thromb Haemost 2000 Dec;84(6):1023-30.
37. Park JB, etal., PLoS One. 2011;6(11):e28327. doi: 10.1371/journal.pone.0028327. Epub 2011 Nov 29.
38. Parunov LA, etal., Thromb Res. 2014 Jan;133(1):112-9. doi: 10.1016/j.thromres.2013.10.036. Epub 2013 Nov 1.
39. Peled E, etal., Thromb Res. 2013 Jan;131(1):94-8. doi: 10.1016/j.thromres.2012.09.018. Epub 2012 Oct 9.
40. Pipeline to import KEGG annotations from KEGG into RGD
41. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
42. Potze W, etal., Br J Haematol. 2013 Sep;162(6):819-26. doi: 10.1111/bjh.12462. Epub 2013 Jul 11.
43. Rancourt RC, etal., Toxicol Appl Pharmacol. 2013 Oct 1;272(1):86-95. doi: 10.1016/j.taap.2013.05.020. Epub 2013 May 30.
44. Ravindranath TM, etal., Clin Appl Thromb Hemost. 2004 Oct;10(4):379-85.
45. RGD automated import pipeline
46. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
47. RGD automated import pipeline for gene-chemical interactions
48. Rogolino A, etal., Blood Coagul Fibrinolysis. 2003 Apr;14(3):277-82.
49. Saito M, etal., Rinsho Ketsueki. 1996 Sep;37(9):794-8.
50. Schjetlein R, etal., Acta Obstet Gynecol Scand. 1999 Mar;78(3):191-7.
51. Schneider P, etal., Br J Haematol. 2010 Feb;148(4):582-92. doi: 10.1111/j.1365-2141.2009.07958.x. Epub 2009 Oct 28.
52. Sidelmann JJ, etal., Blood Coagul Fibrinolysis. 2008 Jul;19(5):405-9. doi: 10.1097/MBC.0b013e3283049639.
53. Smith SA, etal., Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28.
54. Steppich B, etal., Thromb Haemost. 2005 Jan;93(1):35-9.
55. Sun Y, etal., Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008 Jun;16(3):493-6.
56. Tardy-Poncet B, etal., Thromb Res. 2012 Dec;130(6):925-8. doi: 10.1016/j.thromres.2012.07.025. Epub 2012 Oct 15.
57. Ushigome H, etal., J Surg Res. 2002 Feb;102(2):102-9.
58. Westrick RJ, etal., Circulation. 2001 Jun 26;103(25):3044-6.
59. Yamashita T, etal., Circulation 2003 Nov 18;108(20):2450-2. Epub 2003 Nov 10.
60. Yoshimura N, etal., Transplantation. 1999 Jan 15;67(1):45-53.
61. Yu J, etal., Heart Vessels. 2011 Nov;26(6):646-53. doi: 10.1007/s00380-010-0106-0. Epub 2011 Jan 13.
62. Zhu Y, etal., Hunan Yi Ke Da Xue Xue Bao. 2000 Aug 28;25(4):401-2, 405.
Additional References at PubMed
PMID:9493581   PMID:9819035   PMID:9858573   PMID:9974373   PMID:10021455   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12083498   PMID:12477932  
PMID:12520002   PMID:12904583   PMID:14610273   PMID:14660441   PMID:14743444   PMID:15582152   PMID:15598816   PMID:15604416   PMID:16141072   PMID:16141073   PMID:16602821   PMID:17082321  
PMID:17438064   PMID:17967808   PMID:18503630   PMID:18611227   PMID:18799693   PMID:19036061   PMID:19422457   PMID:19648471   PMID:19713537   PMID:20516367   PMID:21233452   PMID:21267068  
PMID:21873635   PMID:22223730   PMID:23038262   PMID:23106863   PMID:23530052   PMID:24006456   PMID:25677604   PMID:25832548   PMID:25945811   PMID:25954015   PMID:26302185   PMID:27875740  
PMID:28550640   PMID:28827327   PMID:29438223   PMID:30188893   PMID:30571485   PMID:30755437   PMID:32735640   PMID:33054088   PMID:33728763  


Genomics

Comparative Map Data
Tfpi
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,263,199 - 84,307,119 (-)NCBIGRCm39mm39
GRCm39 Ensembl284,263,199 - 84,307,119 (-)Ensembl
GRCm38284,432,855 - 84,476,775 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,432,855 - 84,476,775 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,273,017 - 84,316,932 (-)NCBIGRCm37mm9NCBIm37
MGSCv36284,233,699 - 84,275,013 (-)NCBImm8
Celera286,041,007 - 86,084,914 (-)NCBICelera
Cytogenetic Map2DNCBI
TFPI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2187,464,230 - 187,565,760 (-)EnsemblGRCh38hg38GRCh38
GRCh382187,464,230 - 187,554,501 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372188,328,957 - 188,419,162 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362188,037,202 - 188,127,464 (-)NCBINCBI36hg18NCBI36
Build 342188,156,790 - 188,244,556NCBI
Celera2181,925,068 - 182,015,356 (-)NCBI
Cytogenetic Map2q32.1NCBI
HuRef2180,188,532 - 180,278,959 (-)NCBIHuRef
CHM1_12188,334,627 - 188,424,881 (-)NCBICHM1_1
Tfpi
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2369,533,156 - 69,582,547 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl369,533,156 - 69,576,880 (-)Ensembl
Rnor_6.0371,852,738 - 71,902,127 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl371,852,744 - 71,893,618 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0378,373,808 - 78,423,115 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4367,654,389 - 67,697,178 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1367,550,760 - 67,593,550 (-)NCBI
Celera368,890,124 - 68,933,788 (-)NCBICelera
Cytogenetic Map3q24NCBI
Tfpi
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540310,924,893 - 11,004,284 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540310,925,155 - 11,004,229 (+)NCBIChiLan1.0ChiLan1.0
TFPI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B192,541,881 - 192,631,867 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B192,541,881 - 192,581,384 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B74,744,154 - 74,834,338 (-)NCBIMhudiblu_PPA_v0panPan3
TFPI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13629,457,131 - 29,546,455 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3629,459,371 - 29,511,310 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3629,358,584 - 29,410,512 (-)NCBI
ROS_Cfam_1.03629,680,362 - 29,769,683 (-)NCBI
UMICH_Zoey_3.13629,744,554 - 29,796,457 (-)NCBI
UNSW_CanFamBas_1.03629,679,616 - 29,731,462 (-)NCBI
UU_Cfam_GSD_1.03629,848,287 - 29,900,234 (-)NCBI
Tfpi
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303146,663,997 - 146,734,969 (-)NCBI
SpeTri2.0NW_00493650610,103,120 - 10,172,800 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFPI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1592,345,075 - 92,409,905 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11592,345,083 - 92,409,962 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215102,535,224 - 102,694,356 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFPI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11073,004,762 - 73,105,772 (-)NCBI
ChlSab1.1 Ensembl1073,002,522 - 73,105,858 (-)Ensembl
Vero_WHO_p1.0NW_023666040126,397,666 - 126,498,612 (+)NCBI
Tfpi
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248992,401,861 - 2,473,762 (+)NCBI

Position Markers
AW552122  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38284,444,037 - 84,444,127UniSTSGRCm38
MGSCv37284,284,194 - 84,284,284UniSTSGRCm37
Celera286,052,224 - 86,052,314UniSTS
Cytogenetic Map2DUniSTS
Whitehead/MRC_RH21313.45UniSTS
Tfpi  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2DUniSTS
cM Map2 UniSTS
Tfpi  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2DUniSTS
cM Map2 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388608993591306Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357829Lvrq1_mliver weight QTL 1 (mouse)Not determined220892967119064359Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220892967119064359Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220892967119064359Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220892967119064359Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220892967119064359Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220892967119064359Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220892967119064359Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224334620148858457Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229417935148533014Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31324555105313225Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240995481115079684Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245457623145470727Mouse
10755526Lymph1_mlymphocyte differential 1 (mouse)25098897084988970Mouse
1300875Taste1_mtaste-saccharin preference 1 (mouse)Not determined25109283185092934Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25187293285873081Mouse
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25261767586617792Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25261767586617792Mouse
4142299Pbwg1.4_mpostnatal body weight growth 1.4 (mouse)Not determined5562407289624172Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25769377391693944Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25808964792089647Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260690268119525037Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)262000000137000000Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26317561097175769Mouse
1301405Etohr_methanol response acute (mouse)Not determined26317561097175769Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26317561097175769Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26317561097175769Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26317561097175769Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26317561097175769Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26373981097739957Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265439402162677006Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267817543101817798Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267817543101817798Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268893925102894063Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268893925102894063Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74693773114293051Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274693773129371085Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276591138110591306Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276848414103265478Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined281064989115064989Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284178143118178248Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284182854148680255Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284182854148825550Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4648
Count of miRNA genes:679
Interacting mature miRNAs:899
Transcripts:ENSMUST00000028487, ENSMUST00000090732, ENSMUST00000111711, ENSMUST00000111714, ENSMUST00000111717, ENSMUST00000111718, ENSMUST00000111722, ENSMUST00000125677, ENSMUST00000144775, ENSMUST00000150261
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001177319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001177320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001355273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF004833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF016313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY307762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000028487   ⟹   ENSMUSP00000028487
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,263,204 - 84,304,518 (-)Ensembl
GRCm38.p6 Ensembl284,432,860 - 84,474,174 (-)Ensembl
RefSeq Acc Id: ENSMUST00000090732   ⟹   ENSMUSP00000088235
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,270,484 - 84,307,119 (-)Ensembl
GRCm38.p6 Ensembl284,440,140 - 84,476,775 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111711   ⟹   ENSMUSP00000107340
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,270,484 - 84,307,092 (-)Ensembl
GRCm38.p6 Ensembl284,440,140 - 84,476,748 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111714   ⟹   ENSMUSP00000107343
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,270,484 - 84,307,107 (-)Ensembl
GRCm38.p6 Ensembl284,440,140 - 84,476,763 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111717   ⟹   ENSMUSP00000107346
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,271,067 - 84,304,147 (-)Ensembl
GRCm38.p6 Ensembl284,440,723 - 84,473,803 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111718   ⟹   ENSMUSP00000107347
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,263,199 - 84,305,624 (-)Ensembl
GRCm38.p6 Ensembl284,432,855 - 84,475,280 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111722   ⟹   ENSMUSP00000107351
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,263,199 - 84,304,128 (-)Ensembl
GRCm38.p6 Ensembl284,432,855 - 84,473,784 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125677
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,263,204 - 84,264,939 (-)Ensembl
GRCm38.p6 Ensembl284,432,860 - 84,434,595 (-)Ensembl
RefSeq Acc Id: ENSMUST00000144775
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,274,413 - 84,304,143 (-)Ensembl
GRCm38.p6 Ensembl284,444,069 - 84,473,799 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150261   ⟹   ENSMUSP00000122776
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl284,270,484 - 84,288,454 (-)Ensembl
GRCm38.p6 Ensembl284,440,140 - 84,458,110 (-)Ensembl
RefSeq Acc Id: NM_001177319   ⟹   NP_001170790
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,271,067 - 84,307,103 (-)NCBI
GRCm38284,440,723 - 84,476,759 (-)NCBI
MGSCv37284,273,017 - 84,316,932 (-)RGD
Celera286,041,007 - 86,084,914 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001177320   ⟹   NP_001170791
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,271,067 - 84,307,119 (-)NCBI
GRCm38284,440,723 - 84,476,775 (-)NCBI
MGSCv37284,273,017 - 84,316,932 (-)RGD
Celera286,041,007 - 86,084,914 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001355271   ⟹   NP_001342200
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,204 - 84,307,119 (-)NCBI
GRCm38284,432,860 - 84,476,775 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001355273   ⟹   NP_001342202
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,204 - 84,307,103 (-)NCBI
GRCm38284,432,860 - 84,476,759 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011576   ⟹   NP_035706
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,204 - 84,304,518 (-)NCBI
GRCm38284,432,860 - 84,474,174 (-)NCBI
MGSCv37284,273,017 - 84,316,932 (-)RGD
Celera286,041,007 - 86,084,914 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006499145   ⟹   XP_006499208
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,199 - 84,305,339 (-)NCBI
GRCm38284,432,855 - 84,474,986 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006499149   ⟹   XP_006499212
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,271,064 - 84,305,368 (-)NCBI
GRCm38284,440,720 - 84,475,021 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006499150   ⟹   XP_006499213
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,271,064 - 84,305,364 (-)NCBI
GRCm38284,440,720 - 84,475,010 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249392   ⟹   XP_030105252
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,199 - 84,305,339 (-)NCBI
GRCm38284,432,855 - 84,474,986 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249395   ⟹   XP_030105255
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,203 - 84,307,109 (-)NCBI
GRCm38284,432,859 - 84,476,765 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160427   ⟹   XP_036016320
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,199 - 84,307,085 (-)NCBI
RefSeq Acc Id: XM_036160428   ⟹   XP_036016321
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39284,263,203 - 84,307,107 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_035706   ⟸   NM_011576
- Peptide Label: isoform a precursor
- UniProtKB: O54819 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001170791   ⟸   NM_001177320
- Peptide Label: isoform b precursor
- UniProtKB: Q8BSB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001170790   ⟸   NM_001177319
- Peptide Label: isoform b precursor
- UniProtKB: Q8BSB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006499208   ⟸   XM_006499145
- Peptide Label: isoform X1
- UniProtKB: O54819 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006499213   ⟸   XM_006499150
- Peptide Label: isoform X3
- UniProtKB: Q8BSB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006499212   ⟸   XM_006499149
- Peptide Label: isoform X2
- UniProtKB: O54819 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030105252   ⟸   XM_030249392
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030105255   ⟸   XM_030249395
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001342200   ⟸   NM_001355271
- Peptide Label: isoform a precursor
RefSeq Acc Id: NP_001342202   ⟸   NM_001355273
- Peptide Label: isoform a precursor
RefSeq Acc Id: ENSMUSP00000122776   ⟸   ENSMUST00000150261
RefSeq Acc Id: ENSMUSP00000107346   ⟸   ENSMUST00000111717
RefSeq Acc Id: ENSMUSP00000107347   ⟸   ENSMUST00000111718
RefSeq Acc Id: ENSMUSP00000107343   ⟸   ENSMUST00000111714
RefSeq Acc Id: ENSMUSP00000107340   ⟸   ENSMUST00000111711
RefSeq Acc Id: ENSMUSP00000107351   ⟸   ENSMUST00000111722
RefSeq Acc Id: ENSMUSP00000088235   ⟸   ENSMUST00000090732
RefSeq Acc Id: ENSMUSP00000028487   ⟸   ENSMUST00000028487
RefSeq Acc Id: XP_036016320   ⟸   XM_036160427
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036016321   ⟸   XM_036160428
- Peptide Label: isoform X1
Protein Domains
BPTI/Kunitz inhibitor

Promoters
RGD ID:6832927
Promoter ID:MM_KWN:29981
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:ENSMUST00000028487,   ENSMUST00000111712,   ENSMUST00000111717,   ENSMUST00000111722,   OTTMUST00000032486
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36284,314,081 - 84,314,872 (-)MPROMDB
RGD ID:6832926
Promoter ID:MM_KWN:29982
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:ENSMUST00000111718
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36284,316,101 - 84,316,601 (-)MPROMDB
RGD ID:6832925
Promoter ID:MM_KWN:29983
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   ES_Cell,   Liver,   MEF_B6
Transcripts:ENSMUST00000090732,   ENSMUST00000111711,   ENSMUST00000111714
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36284,316,629 - 84,317,129 (-)MPROMDB
RGD ID:6877780
Promoter ID:EPDNEW_M2341
Type:multiple initiation site
Name:Tfpi_2
Description:Mus musculus tissue factor pathway inhibitor , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2342  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38284,474,002 - 84,474,062EPDNEW
RGD ID:6877782
Promoter ID:EPDNEW_M2342
Type:initiation region
Name:Tfpi_1
Description:Mus musculus tissue factor pathway inhibitor , transcript variant3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2341  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38284,476,763 - 84,476,823EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1095418 AgrOrtholog
Ensembl Genes ENSMUSG00000027082 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000028487 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000088235 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000107340 UniProtKB/TrEMBL
  ENSMUSP00000107343 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000107346 UniProtKB/TrEMBL
  ENSMUSP00000107347 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000107351 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000122776 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000028487 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000090732 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000111711 UniProtKB/TrEMBL
  ENSMUST00000111714 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000111717 UniProtKB/TrEMBL
  ENSMUST00000111718 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000111722 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000150261 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 4.10.410.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kunitz_BPTI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kunitz_BPTI_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prtase_inh_Kunz-CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TFPI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21788 UniProtKB/Swiss-Prot
MGD MGI:1095418 ENTREZGENE
NCBI Gene 21788 ENTREZGENE
Pfam Kunitz_BPTI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tfpi PhenoGen
PIRSF TFPI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS BASICPTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BPTI_KUNITZ_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BPTI_KUNITZ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00131 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57362 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2ARA0_MOUSE UniProtKB/TrEMBL
  A2ARA3_MOUSE UniProtKB/TrEMBL
  A2ARA4_MOUSE UniProtKB/TrEMBL
  O54819 ENTREZGENE
  Q8BSB7 ENTREZGENE, UniProtKB/TrEMBL
  Q8CI80_MOUSE UniProtKB/TrEMBL
  TFPI1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9Z2U8 UniProtKB/Swiss-Prot