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Gene: Rfx3 (regulatory factor X, 3 (influences HLA class II expression)) Mus musculus
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Symbol: Rfx3
Name: regulatory factor X, 3 (influences HLA class II expression)
Description: Exhibits DNA-binding transcription factor activity and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including epithelial cilium movement involved in determination of left/right asymmetry; positive regulation of type B pancreatic cell development; and type B pancreatic cell maturation. Localizes to nuclear chromatin. Is expressed in several structures, including central nervous system; genitourinary system; inner cell mass; pancreas; and sensory organ. Used to study visceral heterotaxy. Orthologous to human RFX3 (regulatory factor X3); INTERACTS WITH benzo[a]pyrene; bisphenol A; (-)-epigallocatechin 3-gallate (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C230093O12Rik; MRFX3; regulatory factor X 3; transcription factor RFX3
Orthologs:
Homo sapiens (human) : RFX3 (regulatory factor X3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rfx3 (regulatory factor X3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfx3 (regulatory factor X3)
Pan paniscus (bonobo/pygmy chimpanzee) : RFX3 (regulatory factor X3)
Canis lupus familiaris (dog) : RFX3 (regulatory factor X3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfx3 (regulatory factor X3)
Sus scrofa (pig) : RFX3 (regulatory factor X3)
Chlorocebus sabaeus (African green monkey) : RFX3 (regulatory factor X3)
Heterocephalus glaber (naked mole-rat) : Rfx3 (regulatory factor X3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1927,761,721 - 28,011,166 (-)EnsemblGRCm38mm10GRCm38
GRCm381927,761,721 - 28,014,669 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371927,836,211 - 28,085,656 (-)NCBIGRCm37mm9NCBIm37
MGSCv361927,834,138 - 28,077,137 (-)NCBImm8
Celera1928,539,554 - 28,762,791 (-)NCBICelera
Cytogenetic Map19C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rfx3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317169
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.