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Gene: Rfx3 (regulatory factor X, 3 (influences HLA class II expression)) Mus musculus
Symbol: Rfx3
Name: regulatory factor X, 3 (influences HLA class II expression)
Description: Exhibits DNA-binding transcription factor activity and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including epithelial cilium movement involved in determination of left/right asymmetry; positive regulation of type B pancreatic cell development; and type B pancreatic cell maturation. Localizes to nuclear chromatin. Is expressed in several structures, including central nervous system; genitourinary system; inner cell mass; pancreas; and sensory organ. Used to study visceral heterotaxy. Orthologous to human RFX3 (regulatory factor X3); INTERACTS WITH benzo[a]pyrene; bisphenol A; (-)-epigallocatechin 3-gallate (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C230093O12Rik; MRFX3; regulatory factor X 3; transcription factor RFX3
Homo sapiens (human) : RFX3 (regulatory factor X3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rfx3 (regulatory factor X3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfx3 (regulatory factor X3)
Pan paniscus (bonobo/pygmy chimpanzee) : RFX3 (regulatory factor X3)
Canis lupus familiaris (dog) : RFX3 (regulatory factor X3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfx3 (regulatory factor X3)
Sus scrofa (pig) : RFX3 (regulatory factor X3)
Chlorocebus sabaeus (African green monkey) : RFX3 (regulatory factor X3)
Heterocephalus glaber (naked mole-rat) : Rfx3 (regulatory factor X3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1927,761,721 - 28,011,166 (-)EnsemblGRCm38mm10GRCm38
GRCm381927,761,721 - 28,014,669 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371927,836,211 - 28,085,656 (-)NCBIGRCm37mm9NCBIm37
MGSCv361927,834,138 - 28,077,137 (-)NCBImm8
Celera1928,539,554 - 28,762,791 (-)NCBICelera
Cytogenetic Map19C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rfx3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317169
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.