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Gene: Spink2 (serine peptidase inhibitor, Kazal type 2) Mus musculus
Symbol: Spink2
Name: serine peptidase inhibitor, Kazal type 2
Description: ENCODES a protein that exhibits peptidase inhibitor activity (inferred); INVOLVED IN acrosome assembly; fertilization; male germ cell proliferation; ASSOCIATED WITH abnormal male germ cell apoptosis; abnormal seminiferous tubule morphology; decreased litter size; ASSOCIATED WITH Spermatogenic Failure 29 (ortholog); FOUND IN acrosomal vesicle; cytoplasm; neuron projection; INTERACTS WITH lead diacetate; pirinixic acid; sodium fluoride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700007F22Rik; acrosin-trypsin inhibitor; AV038945; HUSI-II; MGC107139; serine protease inhibitor Kazal-type 2; serine protease inhibitor, Kazal type 2
Homo sapiens (human) : SPINK2 (serine peptidase inhibitor, Kazal type 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spink2 (serine peptidase inhibitor, Kazal type 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spink2 (serine peptidase inhibitor, Kazal type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SPINK2 (serine peptidase inhibitor, Kazal type 2)
Canis lupus familiaris (dog) : SPINK2 (serine peptidase inhibitor, Kazal type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spink2 (serine peptidase inhibitor, Kazal type 2)
Sus scrofa (pig) : SPINK2 (serine peptidase inhibitor, Kazal type 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38577,205,106 - 77,216,258 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37577,634,133 - 77,640,478 (-)NCBIGRCm37mm9NCBIm37
MGSCv36578,279,883 - 78,286,228 (-)NCBImm8
Celera574,471,868 - 74,478,393 (-)NCBICelera
Cytogenetic Map5 C3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Spink2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552067
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.