Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1) - Rat Genome Database

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Gene: Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1) Mus musculus
Analyze
Symbol: Slc11a1
Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
RGD ID: 736533
MGI Page MGI
Description: Enables manganese ion transmembrane transporter activity. Involved in metal ion export. Acts upstream of or within several processes, including cation homeostasis; defense response to other organism; and positive regulation of macromolecule metabolic process. Located in cytoplasmic vesicle and lysosome. Is expressed in several structures, including brain; gut; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Buruli ulcer disease; autoimmune disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); and tuberculosis (multiple). Orthologous to human SLC11A1 (solute carrier family 11 member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bcg; host resistance locus Bcg/Ity/Lsh; It; Ity; Ity1; L; Lsh; MGC129156; MGC129157; N; natural resistance-associated macrophage protein 1; Nr; Nramp; NRAMP 1; Nramp1; solute carrier family 11 member 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm4829   Slc11a1-rs1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,414,318 - 74,429,974 (+)NCBIGRCm39mm39
GRCm39 Ensembl174,414,354 - 74,425,221 (+)Ensembl
GRCm38174,375,014 - 74,386,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,375,195 - 74,386,062 (+)EnsemblGRCm38mm10GRCm38
MGSCv37174,421,777 - 74,432,625 (+)NCBIGRCm37mm9NCBIm37
MGSCv36174,308,436 - 74,319,269 (+)NCBImm8
Celera174,932,506 - 74,943,551 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of protein kinase activity  (IMP)
antigen processing and presentation of peptide antigen  (IMP)
cadmium ion transmembrane transport  (ISO)
cellular cadmium ion homeostasis  (IBA,ISO)
cellular iron ion homeostasis  (IBA,IMP,ISO)
defense response to bacterium  (IMP)
defense response to Gram-negative bacterium  (IMP)
defense response to protozoan  (IMP)
inflammatory response  (IMP)
ion transport  (IEA)
iron ion homeostasis  (IMP)
iron ion transport  (IMP,ISO)
L-arginine transmembrane transport  (IDA)
macrophage activation  (IDA,IMP)
manganese ion transmembrane transport  (IBA)
manganese ion transport  (IMP)
MAPK cascade  (ISO)
metal ion export  (IDA)
metal ion transport  (IEA)
MHC class II biosynthetic process  (IMP)
mRNA stabilization  (IMP)
multicellular organismal iron ion homeostasis  (IMP)
negative regulation of cytokine production  (IMP)
nitrite transport  (IDA)
phagocytosis  (IMP)
positive regulation of cytokine production  (IMP)
positive regulation of dendritic cell antigen processing and presentation  (IMP)
positive regulation of gene expression  (IMP)
positive regulation of interferon-gamma production  (IMP)
positive regulation of phagocytosis  (IMP)
positive regulation of T-helper 1 type immune response  (IMP)
positive regulation of transcription by RNA polymerase II  (IMP)
respiratory burst  (IDA)
response to bacterium  (IMP,ISO)
response to interferon-gamma  (IDA)
response to lipopolysaccharide  (IBA,IDA,IMP,ISO)
T cell proliferation involved in immune response  (IMP)
vacuolar acidification  (IMP)
wound healing  (IMP)

Cellular Component

References

References - curated
1. Akcakaya P, etal., Mol Biol Rep. 2011 Dec 8.
2. Alcais A, etal., J Infect Dis. 2000 Jan;181(1):302-8.
3. Ates O, etal., J Clin Immunol. 2008 Jan;28(1):73-7. Epub 2007 Sep 18.
4. Ates O, etal., Rheumatol Int. 2009 May;29(7):787-91. Epub 2008 Nov 8.
5. Barshes NR, etal., Transpl Infect Dis. 2006 Jun;8(2):108-12.
6. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
7. Borrego A, etal., Microbes Infect. 2006 Oct;8(12-13):2766-71. Epub 2006 Sep 7.
8. Castellucci L, etal., BMC Med Genet. 2010 Jan 20;11:10.
9. Champion OL, etal., Microbes Infect. 2008 Jul;10(8):922-7. Epub 2008 May 14.
10. Chermesh I, etal., Dig Dis Sci. 2007 Jul;52(7):1632-5. Epub 2007 Mar 24.
11. Comabella M, etal., Mult Scler. 2004 Dec;10(6):618-20.
12. Crawford NP, etal., BMC Med Genet. 2005 Mar 9;6:10.
13. Decobert M, etal., J Urol. 2006 Apr;175(4):1506-11.
14. El-Safi S, etal., C R Biol. 2006 Nov;329(11):863-70. Epub 2006 Aug 22.
15. Ferreira FR, etal., Int J Lepr Other Mycobact Dis. 2004 Dec;72(4):457-67.
16. Gazouli M, etal., Can J Neurol Sci. 2008 Sep;35(4):491-4.
17. Gazouli M, etal., Inflamm Bowel Dis. 2008 Oct;14(10):1323-30.
18. Jiang HR, etal., J Leukoc Biol. 2009 Apr;85(4):703-10. Epub 2008 Dec 30.
19. Kissler S, etal., Nat Genet. 2006 Apr;38(4):479-83. Epub 2006 Mar 19.
20. Kojima Y, etal., Tissue Antigens. 2001 Dec;58(6):379-84.
21. Kotlowski R, etal., Inflamm Bowel Dis. 2008 Aug;14(8):1112-7.
22. Mazzolla R, etal., FEMS Immunol Med Microbiol. 2002 Jan 14;32(2):149-58.
23. Meisner SJ, etal., Am J Trop Med Hyg. 2001 Dec;65(6):733-5.
24. MGD and Homologene mouse data transfer
25. MGD data from the GO Consortium
26. MGD IEA
27. Monack DM, etal., J Exp Med. 2004 Jan 19;199(2):231-41.
28. Nishino M, etal., Metabolism. 2005 May;54(5):628-33.
29. OMIM Disease Annotation Pipeline
30. Paccagnini D, etal., PLoS One. 2009 Sep 21;4(9):e7109.
31. Pedroza LS, etal., Lupus. 2011 Mar;20(3):265-73. Epub 2011 Jan 13.
32. Peters LC, etal., Genes Immun. 2007 Jan;8(1):51-6. Epub 2006 Nov 23.
33. RGD automated import pipeline
34. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
35. RGD automated import pipeline for gene-chemical interactions
36. Rodriguez MR, etal., Tissue Antigens. 2002 Apr;59(4):311-5.
37. Romero-Gomez M, etal., Gut. 2004 Mar;53(3):446-50.
38. Sanjeevi CB, etal., Arthritis Rheum. 2000 Jun;43(6):1397-404.
39. Sechi LA, etal., World J Gastroenterol. 2006 Nov 28;12(44):7161-4.
40. Smit JJ, etal., J Immunol. 2003 Jul 15;171(2):754-60.
41. Stagas MK, etal., Med Sci Monit. 2011 Jan;17(1):PH1-6.
42. Stewart LC, etal., World J Gastroenterol. 2010 Dec 7;16(45):5727-31.
43. Valdez Y, etal., Cell Microbiol. 2009 Feb;11(2):351-62. Epub 2008 Nov 3.
44. van Crevel R, etal., J Infect Dis. 2009 Dec 1;200(11):1671-4.
45. Wu F, etal., Biomed Res Int. 2013;2013:484535. doi: 10.1155/2013/484535. Epub 2013 Sep 1.
46. Yang JH, etal., BMC Med Genet. 2011 Apr 27;12:59.
47. Yang YS, etal., J Korean Med Sci. 2000 Feb;15(1):83-7.
48. Zaahl MG, etal., Int J Colorectal Dis. 2006 Jul;21(5):402-8. Epub 2005 Jul 30.
Additional References at PubMed
PMID:290436   PMID:385184   PMID:606434   PMID:1107437   PMID:1358811   PMID:1541907   PMID:1544222   PMID:1581633   PMID:1613775   PMID:1676979   PMID:1834169   PMID:1879934  
PMID:1937036   PMID:1970800   PMID:2212703   PMID:2502336   PMID:2566635   PMID:2696048   PMID:2901325   PMID:2931376   PMID:3242494   PMID:3674828   PMID:3759239   PMID:3882240  
PMID:3920318   PMID:3923111   PMID:3930154   PMID:5337943   PMID:6264778   PMID:6311901   PMID:6315821   PMID:6343242   PMID:6358358   PMID:6361135   PMID:6365754   PMID:6378765  
PMID:6480104   PMID:6527158   PMID:6698599   PMID:6749659   PMID:6790621   PMID:6795274   PMID:6985638   PMID:7001248   PMID:7045675   PMID:7045676   PMID:7047397   PMID:7479731  
PMID:7513015   PMID:7561513   PMID:7613023   PMID:7622220   PMID:7622247   PMID:7650477   PMID:7665187   PMID:7713559   PMID:7737696   PMID:7789986   PMID:7829102   PMID:7894173  
PMID:7894181   PMID:7919662   PMID:7980580   PMID:8033407   PMID:8045593   PMID:8100801   PMID:8132324   PMID:8187330   PMID:8187331   PMID:8244383   PMID:8262646   PMID:8288247  
PMID:8301134   PMID:8358176   PMID:8359899   PMID:8468480   PMID:8473743   PMID:8490962   PMID:8529105   PMID:8603530   PMID:8603532   PMID:8634139   PMID:8642246   PMID:8751373  
PMID:8757814   PMID:8810009   PMID:8871656   PMID:8875897   PMID:8908514   PMID:9000542   PMID:9009318   PMID:9034150   PMID:9176118   PMID:9244347   PMID:9261342   PMID:9271100  
PMID:9479490   PMID:9490047   PMID:9500516   PMID:9507200   PMID:9670047   PMID:9824471   PMID:9893057   PMID:10065630   PMID:10349636   PMID:10417735   PMID:10531233   PMID:10577506  
PMID:10678911   PMID:10899900   PMID:10899910   PMID:10899911   PMID:11016460   PMID:11042159   PMID:11067873   PMID:11076861   PMID:11217851   PMID:11226278   PMID:11261784   PMID:11354828  
PMID:11466385   PMID:11544318   PMID:11599791   PMID:11723074   PMID:11903051   PMID:12055258   PMID:12058254   PMID:12110671   PMID:12174088   PMID:12196193   PMID:12202156   PMID:12368449  
PMID:12429710   PMID:12441401   PMID:12466851   PMID:12477932   PMID:12527228   PMID:12540538   PMID:12625509   PMID:12840021   PMID:12902503   PMID:14681479   PMID:14707092   PMID:15045472  
PMID:15202932   PMID:15210771   PMID:15506949   PMID:15601666   PMID:15781580   PMID:15905556   PMID:16141072   PMID:16141073   PMID:16251362   PMID:16395332   PMID:16470178   PMID:16622216  
PMID:16688529   PMID:16706788   PMID:16706797   PMID:16717117   PMID:16738669   PMID:16836651   PMID:16861683   PMID:16905747   PMID:16926396   PMID:17097837   PMID:17194808   PMID:17328787  
PMID:17486412   PMID:17620357   PMID:17664269   PMID:17726103   PMID:17932044   PMID:17942403   PMID:18045875   PMID:18086376   PMID:18270590   PMID:18285491   PMID:18397382   PMID:18456389  
PMID:18929666   PMID:18984740   PMID:18991287   PMID:19169648   PMID:19321419   PMID:19500110   PMID:19650037   PMID:19700664   PMID:19720755   PMID:19870162   PMID:19870600   PMID:20176950  
PMID:20206555   PMID:20394798   PMID:20660761   PMID:20665098   PMID:20693420   PMID:21183572   PMID:21267068   PMID:21295273   PMID:21376231   PMID:21427231   PMID:21601942   PMID:21633507  
PMID:21677750   PMID:21873635   PMID:22461501   PMID:22624013   PMID:22706314   PMID:22946062   PMID:23166727   PMID:23326430   PMID:23509347   PMID:24367978   PMID:24505471   PMID:24528866  
PMID:25207201   PMID:25350459   PMID:26933955   PMID:27481241   PMID:27599659   PMID:27955815   PMID:28278296   PMID:28360906   PMID:28476637   PMID:28669029   PMID:29140247   PMID:30057174  
PMID:30402460   PMID:30552021   PMID:30861354   PMID:31230160   PMID:31636138   PMID:31753999   PMID:32827218   PMID:33563837  


Genomics

Comparative Map Data
Slc11a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,414,318 - 74,429,974 (+)NCBIGRCm39mm39
GRCm39 Ensembl174,414,354 - 74,425,221 (+)Ensembl
GRCm38174,375,014 - 74,386,057 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,375,195 - 74,386,062 (+)EnsemblGRCm38mm10GRCm38
MGSCv37174,421,777 - 74,432,625 (+)NCBIGRCm37mm9NCBIm37
MGSCv36174,308,436 - 74,319,269 (+)NCBImm8
Celera174,932,506 - 74,943,551 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.54NCBI
SLC11A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2218,382,029 - 218,396,894 (+)EnsemblGRCh38hg38GRCh38
GRCh382218,381,766 - 218,396,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372219,246,996 - 219,261,617 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,954,996 - 218,969,861 (+)NCBINCBI36hg18NCBI36
Build 342219,072,421 - 219,086,002NCBI
Celera2213,013,369 - 213,028,238 (+)NCBI
Cytogenetic Map2q35NCBI
HuRef2211,100,043 - 211,114,917 (+)NCBIHuRef
CHM1_12219,253,406 - 219,268,272 (+)NCBICHM1_1
Slc11a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2975,957,193 - 75,968,115 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl975,957,316 - 75,968,101 (+)Ensembl
Rnor_6.0981,655,590 - 81,666,697 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,655,629 - 81,666,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,420,556 - 81,431,345 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,714,692 - 73,725,523 (+)NCBIRGSC3.4rn4RGSC3.4
Celera973,531,012 - 73,541,597 (+)NCBICelera
Cytogenetic Map9q33NCBI
Slc11a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545314,980,562 - 14,995,608 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545314,980,562 - 14,995,118 (-)NCBIChiLan1.0ChiLan1.0
SLC11A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B224,238,284 - 224,252,941 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B224,238,284 - 224,252,941 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B105,640,613 - 105,655,524 (+)NCBIMhudiblu_PPA_v0panPan3
SLC11A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,039,203 - 25,047,461 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3725,038,360 - 25,047,282 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3725,859,294 - 25,867,379 (+)NCBI
ROS_Cfam_1.03725,054,994 - 25,063,083 (+)NCBI
ROS_Cfam_1.0 Ensembl3725,053,097 - 25,063,084 (+)Ensembl
UMICH_Zoey_3.13724,960,561 - 24,968,638 (+)NCBI
UNSW_CanFamBas_1.03724,894,238 - 24,902,300 (+)NCBI
UU_Cfam_GSD_1.03724,914,545 - 24,922,623 (+)NCBI
Slc11a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,544,696 - 174,553,261 (+)NCBI
SpeTri2.0NW_004936569888,309 - 895,991 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC11A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15120,433,952 - 120,446,396 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115120,434,100 - 120,446,396 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215133,452,820 - 133,454,896 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC11A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,276,553 - 104,288,466 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604095,112,392 - 95,128,910 (-)NCBIVero_WHO_p1.0
Slc11a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248236,612,452 - 6,625,047 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D1Mcg4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,374,801 - 74,374,974UniSTSGRCm38
MGSCv37174,421,375 - 74,421,548UniSTSGRCm37
Celera174,932,108 - 74,932,277UniSTS
Cytogenetic Map1C5UniSTS
Cytogenetic Map1C3UniSTS
cM Map140.8UniSTS
cM Map139.5UniSTS
Slc11a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38174,385,762 - 74,385,889UniSTSGRCm38
MGSCv37174,432,336 - 74,432,463UniSTSGRCm37
Celera174,943,262 - 74,943,389UniSTS
Cytogenetic Map1C3UniSTS
cM Map139.2UniSTS
Slc11a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1C3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1301954Lrnx11_mlearning-contextual 11 (mouse)Not determined13909372774477206Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139093727126517573Mouse
1301166Thypr2_mthymocyte proliferative response 2 (mouse)Not determined14123396575234112Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14123624075236240Mouse
4141032Wbcc1_mwhite blood cell count 1 (mouse)Not determined4222050876220508Mouse
1301714Vertcling_mvertical clinging (mouse)Not determined14289887276899008Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1301670Ssta1_msusceptibility to Salmonella typhimurium antigens 1 (mouse)Not determined14590759679907723Mouse
1301225Sle7_msystematic lupus erythematosus susceptibility 7 (mouse)Not determined14681553180815680Mouse
1301616Yaa2_mY-linked autoimmune acceleration 2 (mouse)Not determined14681553180815680Mouse
1558905Gct7_mgranulosa cell tumorigenesis 7 (mouse)Not determined14731073581310854Mouse
1558822Vas1_mautoimmune vasitis resistance 1 (mouse)Not determined14884984782850051Mouse
1301211Bbaa11_mB.burgdorferi-associated arthritis 11 (mouse)Not determined14884984782850051Mouse
1301430Cdcs2_mcytokine deficiency colitis susceptibility 2 (mouse)Not determined14885318682853326Mouse
10043965Obq24_mobesity QTL 24 (mouse)Not determined15085105784851057Mouse
4141305Tgq9_mtriglyceride QTL 9 (mouse)Not determined5138244685382446Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
1357741Nidd5k_mNidd5 on KK-A<y> (mouse)Not determined15593578989935898Mouse
1357505Vtbt1_mvertebral trabecular bone trait 1 (mouse)Not determined15622705590227201Mouse
4142467Wbcq1_mwhite blood cell quantitative locus 1 (mouse)Not determined15622705590227201Mouse
1301933Insq6_minsulin QTL 6 (mouse)Not determined15668776390687918Mouse
1558717Ses1a_msalmonella enteritidis susceptibility 1a (mouse)Not determined15668776390687918Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15790219291902192Mouse
14747009Manh49_mmandible shape 49 (mouse)15790219291902192Mouse
1300746Skl1_mskeletal size (tail length) 1 (mouse)Not determined15795281891952921Mouse
1357679Egrm1_mearly growth rate, maternal effect 1 (mouse)Not determined15795281891952921Mouse
1301162Skull1_mskull morphology 1 (mouse)Not determined15795281891952921Mouse
1301444Alcw5_malcohol withdrawal 5 (mouse)Not determined15857254792572799Mouse
1301667Lxw5_mlupus BXSB x NZW 5 (mouse)Not determined15857254792572799Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162907596120601949Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
1302119Cia15_mcollagen induced arthritis 15 (mouse)Not determined16584984788568379Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167300000129800000Mouse
4141625Emo4_memotionality 4 (mouse)Not determined6803218686307305Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170205811104211835Mouse
4141393Mol2_mmodifier of LPS-response 2 (mouse)Not determined7158552078206507Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173227055108910684Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73687970107688108Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173687970107688108Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
14697705Stsl3b_mSalmonella typhimurium susceptibility locus 3b (mouse)17410000081800000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1645
Count of miRNA genes:653
Interacting mature miRNAs:792
Transcripts:ENSMUST00000027368, ENSMUST00000127487, ENSMUST00000131511, ENSMUST00000133896, ENSMUST00000134189, ENSMUST00000135137, ENSMUST00000136786, ENSMUST00000147233, ENSMUST00000149166, ENSMUST00000155865
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006495774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC098570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH004789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ458183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB873183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC109137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC109138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L13732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X75355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000027368   ⟹   ENSMUSP00000027368
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,414,362 - 74,425,221 (+)Ensembl
GRCm38.p6 Ensembl174,375,203 - 74,386,062 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127487
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,422,193 - 74,422,993 (+)Ensembl
GRCm38.p6 Ensembl174,383,034 - 74,383,834 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131511
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,414,384 - 74,425,210 (+)Ensembl
GRCm38.p6 Ensembl174,375,225 - 74,386,051 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133896
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,420,810 - 74,423,332 (+)Ensembl
GRCm38.p6 Ensembl174,381,651 - 74,384,173 (+)Ensembl
RefSeq Acc Id: ENSMUST00000134189
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,422,759 - 74,424,356 (+)Ensembl
GRCm38.p6 Ensembl174,383,600 - 74,385,197 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135137
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,414,731 - 74,416,049 (+)Ensembl
GRCm38.p6 Ensembl174,375,572 - 74,376,890 (+)Ensembl
RefSeq Acc Id: ENSMUST00000136786
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,414,412 - 74,420,985 (+)Ensembl
GRCm38.p6 Ensembl174,375,253 - 74,381,826 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147233
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,414,362 - 74,425,211 (+)Ensembl
GRCm38.p6 Ensembl174,375,203 - 74,386,052 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149166
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,422,500 - 74,423,332 (+)Ensembl
GRCm38.p6 Ensembl174,383,341 - 74,384,173 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155865
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,415,816 - 74,419,015 (+)Ensembl
GRCm38.p6 Ensembl174,376,657 - 74,379,856 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187516   ⟹   ENSMUSP00000139455
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl174,414,354 - 74,424,914 (+)Ensembl
GRCm38.p6 Ensembl174,375,195 - 74,385,755 (+)Ensembl
RefSeq Acc Id: NM_013612   ⟹   NP_038640
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,414,362 - 74,425,210 (+)NCBI
GRCm38174,375,203 - 74,386,051 (+)NCBI
MGSCv37174,421,777 - 74,432,625 (+)RGD
Celera174,932,506 - 74,943,551 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006495774   ⟹   XP_006495837
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,414,319 - 74,429,974 (+)NCBI
GRCm38174,375,159 - 74,386,057 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162732   ⟹   XP_036018625
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,414,318 - 74,429,974 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162734   ⟹   XP_036018627
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,414,318 - 74,429,974 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162735   ⟹   XP_036018628
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39174,414,318 - 74,429,974 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_038640   ⟸   NM_013612
- UniProtKB: P41251 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006495837   ⟸   XM_006495774
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000027368   ⟸   ENSMUST00000027368
RefSeq Acc Id: ENSMUSP00000139455   ⟸   ENSMUST00000187516
RefSeq Acc Id: XP_036018627   ⟸   XM_036162734
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036018625   ⟸   XM_036162732
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036018628   ⟸   XM_036162735
- Peptide Label: isoform X1

Promoters
RGD ID:6874066
Promoter ID:EPDNEW_M484
Type:initiation region
Name:Slc11a1_1
Description:Mus musculus solute carrier family 11 (proton-coupled divalentmetal ion transporters), member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38174,375,223 - 74,375,283EPDNEW
RGD ID:6818468
Promoter ID:MM_KWN:1164
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000040229,   OTTMUST00000040230,   OTTMUST00000040231,   OTTMUST00000040232,   OTTMUST00000040233
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36174,421,631 - 74,422,131 (+)MPROMDB
RGD ID:6818469
Promoter ID:MM_KWN:1165
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000040234
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36174,422,806 - 74,423,357 (+)MPROMDB
RGD ID:6818470
Promoter ID:MM_KWN:1166
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000040235
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36174,427,456 - 74,428,437 (+)MPROMDB
RGD ID:6818471
Promoter ID:MM_KWN:1167
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000040236,   OTTMUST00000040237,   OTTMUST00000040238
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36174,428,806 - 74,430,087 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1345275 AgrOrtholog
Ensembl Genes ENSMUSG00000026177 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000027368 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000139455 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027368 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000187516 UniProtKB/TrEMBL
InterPro NRAMP_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18173 UniProtKB/Swiss-Prot
MGD MGI:1345275 ENTREZGENE
NCBI Gene 18173 ENTREZGENE
PANTHER PTHR11706 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Nramp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc11a1 PhenoGen
PRINTS NATRESASSCMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs nramp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WNR0_MOUSE UniProtKB/TrEMBL
  NRAM1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3TB84 UniProtKB/Swiss-Prot