Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-pilocarpine | increases expression | ISO | RGD:3241 | 6480464 | Pilocarpine results in increased expression of P2RX7 protein | CTD | PMID:19138473 | (+)-schisandrin B | multiple interactions | ISO | RGD:3241 | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of P2RX7 mRNA] | CTD | PMID:31150632 | (R)-adrenaline | decreases activity | ISO | RGD:730814 | 6480464 | Epinephrine results in decreased activity of P2RX7 protein | CTD | PMID:15459114 | 1,1-dichloroethene | increases expression | EXP | | 6480464 | vinylidene chloride results in increased expression of P2RX7 mRNA | CTD | PMID:26682919 | 1,2-dichloroethane | affects expression | EXP | | 6480464 | ethylene dichloride affects the expression of P2RX7 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of P2RX7 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | RGD:730814 | 6480464 | 2 more ... | CTD | PMID:23146750 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:730814 | 6480464 | Tetrachlorodibenzodioxin affects the expression of P2RX7 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:3241 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of P2RX7 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of P2RX7 mRNA | CTD | PMID:21570461, PMID:26377647 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | RGD:3241 | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4,6-trinitrobenzenesulfonic acid | increases expression | ISO | RGD:3241 | 6480464 | Trinitrobenzenesulfonic Acid results in increased expression of P2RX7 mRNA | CTD | PMID:23537331 | 2,4-diaminotoluene | decreases expression | EXP | | 6480464 | 2, 4-diaminotoluene results in decreased expression of P2RX7 mRNA | CTD | PMID:20713471 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:730814 | 6480464 | Lactic Acid results in decreased expression of P2RX7 mRNA | CTD | PMID:30851411 | 3'-O-(4-Benzoyl)benzoyl ATP | multiple interactions | ISO | RGD:730814 | 6480464 | [3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium more ... | CTD | PMID:21320518 | 3'-O-(4-Benzoyl)benzoyl ATP | increases activity | ISO | RGD:730814 | 6480464 | 3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein | CTD | PMID:29642561 | 3'-O-(4-Benzoyl)benzoyl ATP | increases expression | EXP | | 6480464 | 3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased expression of P2RX7 protein | CTD | PMID:26522449 | 3'-O-(4-Benzoyl)benzoyl ATP | multiple interactions | EXP | | 6480464 | 3-5-2 more ... | CTD | PMID:26522449, PMID:27466191 | 3'-O-(4-Benzoyl)benzoyl ATP | decreases response to substance | EXP | | 6480464 | P2RX7 gene mutant form results in decreased susceptibility to 3'-O-4-benzoylbenzoyladenosine 5'-triphosphate | CTD | PMID:17728465, PMID:24101734 | 3'-O-(4-Benzoyl)benzoyl ATP | affects response to substance | EXP | | 6480464 | P2RX7 protein affects the susceptibility to 3'-O-4-benzoylbenzoyladenosine 5'-triphosphate | CTD | PMID:12873706 | 3'-O-(4-Benzoyl)benzoyl ATP | increases activity | EXP | | 6480464 | 3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein | CTD | PMID:27466191 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of P2RX7 mRNA | CTD | PMID:19285098 | 3-chloropropane-1,2-diol | affects expression | ISO | RGD:3241 | 6480464 | alpha-Chlorohydrin affects the expression of P2RX7 mRNA | CTD | PMID:28522335 | 3-methylcholanthrene | decreases expression | EXP | | 6480464 | Methylcholanthrene results in decreased expression of P2RX7 mRNA | CTD | PMID:20713471 | 3-methylcholanthrene | multiple interactions | EXP | | 6480464 | [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA | CTD | PMID:23519560 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of P2RX7 mRNA | CTD | PMID:28973697 | 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid | multiple interactions | EXP | | 6480464 | pyridoxal phosphate-6-azophenyl-2', 4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein] | CTD | PMID:21638035 | adenosine 5'-[gamma-thio]triphosphate | affects response to substance | EXP | | 6480464 | P2RX7 protein affects the susceptibility to adenosine 5'-O-3-thiotriphosphate | CTD | PMID:12873706 | aflatoxin B1 | decreases expression | ISO | RGD:730814 | 6480464 | Aflatoxin B1 results in decreased expression of P2RX7 mRNA | CTD | PMID:27153756 | aflatoxin B1 | increases methylation | ISO | RGD:730814 | 6480464 | Aflatoxin B1 results in increased methylation of P2RX7 intron | CTD | PMID:30157460 | aldehydo-D-glucose | increases expression | ISO | RGD:3241 | 6480464 | Glucose results in increased expression of P2RX7 mRNA | CTD | PMID:21832250 | ammonium chloride | affects expression | ISO | RGD:3241 | 6480464 | Ammonium Chloride affects the expression of P2RX7 mRNA | CTD | PMID:16483693 | antirheumatic drug | decreases expression | ISO | RGD:730814 | 6480464 | Antirheumatic Agents results in decreased expression of P2RX7 mRNA | CTD | PMID:24449571 | apigenin | multiple interactions | ISO | RGD:3241 | 6480464 | Apigenin inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein] | CTD | PMID:25935278 | arsane | multiple interactions | ISO | RGD:730814 | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of P2RX7 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | RGD:730814 | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of P2RX7 mRNA | CTD | PMID:32525701 | ATP | multiple interactions | ISO | RGD:730814 | 6480464 | [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA more ... | CTD | PMID:11003599 more ... | ATP | increases expression | EXP | | 6480464 | Adenosine Triphosphate results in increased expression of P2RX7 protein | CTD | PMID:26522449 | ATP | decreases response to substance | EXP | | 6480464 | P2RX7 gene mutant form results in decreased susceptibility to Adenosine Triphosphate | CTD | PMID:17728465 more ... | ATP | increases response to substance | EXP | | 6480464 | P2RX7 protein results in increased susceptibility to Adenosine Triphosphate | CTD | PMID:23565201 | ATP | multiple interactions | EXP | | 6480464 | 3-5-2 more ... | CTD | PMID:21638035, PMID:26522449 | ATP | increases activity | EXP | | 6480464 | Adenosine Triphosphate results in increased activity of P2RX7 protein | CTD | PMID:19023039 more ... | ATP | increases activity | ISO | RGD:3241 | 6480464 | Adenosine Triphosphate results in increased activity of P2RX7 protein | CTD | PMID:19023039 | ATP | increases activity | ISO | RGD:730814 | 6480464 | Adenosine Triphosphate results in increased activity of P2RX7 protein | CTD | PMID:19023039, PMID:30545933 | avobenzone | decreases expression | ISO | RGD:730814 | 6480464 | avobenzone results in decreased expression of P2RX7 mRNA | CTD | PMID:31016361 | azetidine | multiple interactions | EXP | | 6480464 | azetidine analog inhibits the reaction [3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased expression of P2RX7 protein], azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of P2RX7 protein] | CTD | PMID:26522449 | barium(0) | multiple interactions | ISO | RGD:730814 | 6480464 | P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium] | CTD | PMID:11003599 | benzene | increases expression | ISO | RGD:730814 | 6480464 | Benzene results in increased expression of P2RX7 mRNA | CTD | PMID:19162166 | benzo[a]pyrene | increases expression | ISO | RGD:730814 | 6480464 | Benzoapyrene results in increased expression of P2RX7 protein | CTD | PMID:26657896 | benzo[a]pyrene | affects methylation | ISO | RGD:730814 | 6480464 | Benzoapyrene affects the methylation of P2RX7 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | RGD:730814 | 6480464 | Benzoapyrene results in increased methylation of P2RX7 5' UTR, Benzoapyrene results in increased methylation of P2RX7 exon | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzoapyrene results in increased expression of P2RX7 mRNA | CTD | PMID:19770486 more ... | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzoapyrene results in decreased expression of P2RX7 mRNA | CTD | PMID:20713471 | benzo[a]pyrene | decreases expression | ISO | RGD:730814 | 6480464 | Benzoapyrene results in decreased expression of P2RX7 mRNA | CTD | PMID:20064835 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzobfluoranthene results in increased expression of P2RX7 mRNA | CTD | PMID:26377693 | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | CTD | PMID:27858113 | Benzo[k]fluoranthene | increases expression | EXP | | 6480464 | benzokfluoranthene results in increased expression of P2RX7 mRNA | CTD | PMID:26377693 | berberine | multiple interactions | ISO | RGD:730814 | 6480464 | Berberine affects the reaction [3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] | CTD | PMID:21320518 | bisphenol A | decreases expression | ISO | RGD:3241 | 6480464 | bisphenol A results in decreased expression of P2RX7 mRNA | CTD | PMID:25181051 | C60 fullerene | multiple interactions | EXP | | 6480464 | P2RX7 protein affects the reaction [fullerene C60 results in increased secretion of HMGB1 protein] | CTD | PMID:31504961 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of P2RX7 mRNA | CTD | PMID:31614173 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of P2RX7 mRNA | CTD | PMID:31614173 | calcium atom | multiple interactions | ISO | RGD:730814 | 6480464 | [3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium more ... | CTD | PMID:21320518 | calcium(0) | multiple interactions | ISO | RGD:730814 | 6480464 | [3'-O-4-benzoylbenzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium more ... | CTD | PMID:21320518 | carbon nanotube | multiple interactions | EXP | | 6480464 | P2RX7 protein affects the reaction [Nanotubes, Carbon results in increased secretion of HMGB1 protein] | CTD | PMID:31504961 | carbon nanotube | increases expression | ISO | RGD:730814 | 6480464 | Nanotubes, Carbon results in increased expression of P2RX7 mRNA | CTD | PMID:32649966 | carrageenan | multiple interactions | ISO | RGD:3241 | 6480464 | [N-1-cyanoimino5-quinolinylamino methyl amino-2 more ... | CTD | PMID:16982702 | casticin | increases expression | EXP | | 6480464 | casticin results in increased expression of P2RX7 mRNA | CTD | PMID:28444820 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of P2RX7 mRNA | CTD | PMID:20938992 | chrysene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | CTD | PMID:27858113 | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of P2RX7 mRNA, Cisplatin results in increased expression of P2RX7 protein | CTD | PMID:21151649, PMID:25308879 | cyclosporin A | increases expression | ISO | RGD:730814 | 6480464 | Cyclosporine results in increased expression of P2RX7 mRNA | CTD | PMID:20106945 | D-glucose | increases expression | ISO | RGD:3241 | 6480464 | Glucose results in increased expression of P2RX7 mRNA | CTD | PMID:21832250 | dextran sulfate | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P2RX7 mRNA | CTD | PMID:29950665 | dibenz[a,h]anthracene | increases expression | EXP | | 6480464 | 1 more ... | CTD | PMID:26377693 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of P2RX7 mRNA | CTD | PMID:21266533 | diclofenac | increases expression | EXP | | 6480464 | Diclofenac results in increased expression of P2RX7 mRNA | CTD | PMID:26934552 | diclofenac | multiple interactions | ISO | RGD:3241 | 6480464 | Diclofenac inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein] | CTD | PMID:25935278 | diethyl maleate | decreases expression | ISO | RGD:3241 | 6480464 | diethyl maleate results in decreased expression of P2RX7 mRNA | CTD | PMID:21161181 | doxorubicin | affects expression | EXP | | 6480464 | Doxorubicin affects the expression of P2RX7 | CTD | PMID:17402594 | endosulfan | decreases expression | ISO | RGD:3241 | 6480464 | Endosulfan results in decreased expression of P2RX7 mRNA | CTD | PMID:29391264 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of P2RX7 mRNA | CTD | PMID:30319688 | ethidium | decreases transport | ISO | RGD:730814 | 6480464 | P2RX7 gene polymorphism results in decreased transport of Ethidium | CTD | PMID:16263709 | ethidium | increases transport | ISO | RGD:730814 | 6480464 | P2RX7 protein results in increased transport of Ethidium | CTD | PMID:16263709 | etoposide | increases expression | EXP | | 6480464 | Etoposide results in increased expression of P2RX7 mRNA | CTD | PMID:25270620 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of P2RX7 mRNA | CTD | PMID:20938992 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of P2RX7 mRNA | CTD | PMID:25006883 | furan | decreases expression | ISO | RGD:3241 | 6480464 | furan results in decreased expression of P2RX7 mRNA | CTD | PMID:25539665, PMID:27387713 | gamma-aminobutyric acid | decreases expression | ISO | RGD:3241 | 6480464 | gamma-Aminobutyric Acid results in decreased expression of P2RX7 mRNA | CTD | PMID:26924987 | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of P2RX7 mRNA | CTD | PMID:22553218 | ginsenoside C-K | decreases response to substance | EXP | | 6480464 | P2RX7 gene mutant form results in decreased susceptibility to ginsenoside M1 | CTD | PMID:30545933 | ginsenoside Rd | decreases response to substance | EXP | | 6480464 | P2RX7 gene mutant form results in decreased susceptibility to ginsenoside Rd | CTD | PMID:30545933 | glucose | increases expression | ISO | RGD:3241 | 6480464 | Glucose results in increased expression of P2RX7 mRNA | CTD | PMID:21832250 | graphene oxide | multiple interactions | EXP | | 6480464 | P2RX7 protein affects the reaction [graphene oxide results in increased secretion of HMGB1 protein] | CTD | PMID:31504961 | hexadecanoic acid | multiple interactions | ISO | RGD:3241 | 6480464 | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA more ... | CTD | PMID:25348860 | iron atom | increases expression | ISO | RGD:730814 | 6480464 | Iron deficiency results in increased expression of P2RX7 mRNA | CTD | PMID:20368581 | iron(0) | increases expression | ISO | RGD:730814 | 6480464 | Iron deficiency results in increased expression of P2RX7 mRNA | CTD | PMID:20368581 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of P2RX7 mRNA | CTD | PMID:20938992 | lead diacetate | increases expression | ISO | RGD:3241 | 6480464 | lead acetate results in increased expression of P2RX7 mRNA, lead acetate results in increased expression of P2RX7 protein | CTD | PMID:20932874 more ... | lipopolysaccharide | multiple interactions | ISO | RGD:730814 | 6480464 | [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA more ... | CTD | PMID:24149798 | lipopolysaccharide | decreases expression | EXP | | 6480464 | Lipopolysaccharides results in decreased expression of P2RX7 mRNA alternative form | CTD | PMID:26068648 | melittin | increases response to substance | ISO | RGD:730814 | 6480464 | P2RX7 protein results in increased susceptibility to Melitten | CTD | PMID:22613720 | melittin | increases activity | ISO | RGD:730814 | 6480464 | Melitten results in increased activity of P2RX7 protein | CTD | PMID:22613720 | metformin | increases expression | ISO | RGD:3241 | 6480464 | Metformin results in increased expression of P2RX7 mRNA | CTD | PMID:31324951 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of P2RX7 mRNA] | CTD | PMID:17942915 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of P2RX7 mRNA | CTD | PMID:17942915, PMID:24535843 | nevirapine | decreases expression | ISO | RGD:3241 | 6480464 | Nevirapine results in decreased expression of P2RX7 mRNA | CTD | PMID:23947594 | nickel atom | decreases expression | ISO | RGD:730814 | 6480464 | Nickel results in decreased expression of P2RX7 mRNA | CTD | PMID:23195993 | oleic acid | multiple interactions | ISO | RGD:3241 | 6480464 | [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA more ... | CTD | PMID:25348860 | paracetamol | increases expression | ISO | RGD:730814 | 6480464 | Acetaminophen results in increased expression of P2RX7 mRNA | CTD | PMID:29067470 | paraquat | affects expression | ISO | RGD:3241 | 6480464 | Paraquat affects the expression of P2RX7 mRNA | CTD | PMID:18198484 | perfluorononanoic acid | increases expression | ISO | RGD:730814 | 6480464 | perfluorononanoic acid results in increased expression of P2RX7 mRNA | CTD | PMID:32588087 | phenformin | increases expression | ISO | RGD:3241 | 6480464 | Phenformin results in increased expression of P2RX7 mRNA | CTD | PMID:31324951 | phorbol 13-acetate 12-myristate | multiple interactions | EXP | | 6480464 | [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA | CTD | PMID:23519560 | poly(I:C) | decreases expression | EXP | | 6480464 | Poly I-C results in decreased expression of P2RX7 protein | CTD | PMID:23516405 | poly(I:C) | multiple interactions | EXP | | 6480464 | Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RX7 protein] | CTD | PMID:23516405 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | RGD:3241 | 6480464 | Pregnenolone Carbonitrile results in increased expression of P2RX7 mRNA | CTD | PMID:19162173 | protein kinase inhibitor | multiple interactions | ISO | RGD:730814 | 6480464 | Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of P2RX7 mRNA] | CTD | PMID:28003376 | rac-lactic acid | decreases expression | ISO | RGD:730814 | 6480464 | Lactic Acid results in decreased expression of P2RX7 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | RGD:730814 | 6480464 | resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA], resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein] | CTD | PMID:24149798 | resveratrol | multiple interactions | ISO | RGD:3241 | 6480464 | resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA], resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] | CTD | PMID:25348860 | sevoflurane | affects expression | ISO | RGD:3241 | 6480464 | sevoflurane affects the expression of P2RX7 mRNA | CTD | PMID:15967596 | silicon dioxide | decreases expression | ISO | RGD:730814 | 6480464 | Silicon Dioxide analog results in decreased expression of P2RX7 mRNA | CTD | PMID:23806026 | silver atom | increases expression | EXP | | 6480464 | Silver results in increased expression of P2RX7 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | EXP | | 6480464 | Silver results in increased expression of P2RX7 mRNA | CTD | PMID:27131904 | sodium arsenate | multiple interactions | ISO | RGD:730814 | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of P2RX7 mRNA | CTD | PMID:32525701 | suramin | multiple interactions | EXP | | 6480464 | Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RX7 protein] | CTD | PMID:23516405 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of P2RX7 mRNA | CTD | PMID:17484886 | tetrachloromethane | multiple interactions | ISO | RGD:3241 | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of P2RX7 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | RGD:3241 | 6480464 | Carbon Tetrachloride results in decreased expression of P2RX7 mRNA | CTD | PMID:31150632 | tetraphene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in increased expression of P2RX7 mRNA | CTD | PMID:27858113 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of P2RX7 mRNA, titanium dioxide results in increased expression of P2RX7 protein | CTD | PMID:23557971, PMID:28646487 | titanium dioxide | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P2RX7 mRNA | CTD | PMID:29950665 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of P2RX7 mRNA | CTD | PMID:29128614, PMID:29264374 | toluene 2,4-diisocyanate | multiple interactions | ISO | RGD:730814 | 6480464 | P2RX7 protein promotes the reaction [Toluene 2 more ... | CTD | PMID:26072274, PMID:29940203 | toluene 2,4-diisocyanate | affects response to substance | ISO | RGD:730814 | 6480464 | P2RX7 gene SNP affects the susceptibility to Toluene 2, 4-Diisocyanate | CTD | PMID:29940203 | Triptolide | increases expression | ISO | RGD:3241 | 6480464 | triptolide results in increased expression of P2RX7 protein | CTD | PMID:32519852 | tris(2-chloroethyl) phosphate | increases expression | ISO | RGD:730814 | 6480464 | trischloroethylphosphate results in increased expression of P2RX7 mRNA | CTD | PMID:29143341 | vincristine | multiple interactions | ISO | RGD:3241 | 6480464 | [N-1-cyanoimino5-quinolinylamino methyl amino-2 more ... | CTD | PMID:16982702 | |
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| Save what matters to you |
| {{ loginError }} |
| Sign in with your RGD account |
| Create New Account | Recover Password |
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
Click to see Annotation Detail View
|
|
Gene-Chemical Interaction Annotations
Click to see Annotation Detail View
Gene Ontology Annotations
Click to see Annotation Detail View
Biological Process
|
|
|
Cellular Component
|
|
|
Molecular Function
|
|
|
Phenotype Annotations
Click to see Annotation Detail View
Mammalian Phenotype
|
|
|
References
References - curated
| 1. | MGD and Homologene mouse data transfer |
| 2. | MGD data from the GO Consortium |
| 3. | MGD IEA |
| 4. | RGD automated import pipeline |
| 5. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:9849870 | PMID:10349636 | PMID:10395640 | PMID:11016935 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:11489964 | PMID:11544199 | PMID:11544318 | PMID:11904160 | PMID:12055263 |
| PMID:12370338 | PMID:12466305 | PMID:12466851 | PMID:12477932 | PMID:12598620 | PMID:12621313 | PMID:12677010 | PMID:12759456 | PMID:12796490 | PMID:12814360 | PMID:12968021 | PMID:14511112 |
| PMID:14610273 | PMID:14696971 | PMID:14761980 | PMID:14996828 | PMID:15070812 | PMID:15075209 | PMID:15200422 | PMID:15240711 | PMID:15254086 | PMID:15277380 | PMID:15331634 | PMID:15350640 |
| PMID:15640761 | PMID:15670583 | PMID:15713258 | PMID:15777864 | PMID:15845532 | PMID:15899033 | PMID:15905573 | PMID:15914561 | PMID:15937334 | PMID:15964665 | PMID:15978588 | PMID:15984421 |
| PMID:16027239 | PMID:16116196 | PMID:16141072 | PMID:16141073 | PMID:16198349 | PMID:16207496 | PMID:16269410 | PMID:16301672 | PMID:16325464 | PMID:16455971 | PMID:16493071 | PMID:16565512 |
| PMID:16571660 | PMID:16602821 | PMID:16817206 | PMID:16836656 | PMID:16920919 | PMID:16969386 | PMID:16985003 | PMID:17135244 | PMID:17175137 | PMID:17286969 | PMID:17304630 | PMID:17306762 |
| PMID:17339442 | PMID:17364502 | PMID:17448897 | PMID:17491021 | PMID:17498208 | PMID:17544414 | PMID:17641058 | PMID:17651941 | PMID:17675190 | PMID:17702819 | PMID:17785580 | PMID:17785807 |
| PMID:17803959 | PMID:17825926 | PMID:17849469 | PMID:17905568 | PMID:17962183 | PMID:18082965 | PMID:18097031 | PMID:18211888 | PMID:18293404 | PMID:18305483 | PMID:18384650 | PMID:18407780 |
| PMID:18445587 | PMID:18490713 | PMID:18501702 | PMID:18502993 | PMID:18519738 | PMID:18523246 | PMID:18596211 | PMID:18652259 | PMID:18657557 | PMID:18691411 | PMID:18768840 | PMID:18848528 |
| PMID:18942742 | PMID:18987356 | PMID:18996151 | PMID:19047635 | PMID:19051251 | PMID:19066285 | PMID:19076210 | PMID:19097994 | PMID:19151591 | PMID:19171786 | PMID:19174470 | PMID:19174471 |
| PMID:19201858 | PMID:19204004 | PMID:19211924 | PMID:19234185 | PMID:19276178 | PMID:19299738 | PMID:19304656 | PMID:19308630 | PMID:19309360 | PMID:19342685 | PMID:19379509 | PMID:19385050 |
| PMID:19389853 | PMID:19396427 | PMID:19403602 | PMID:19426712 | PMID:19439191 | PMID:19536133 | PMID:19542469 | PMID:19546214 | PMID:19547756 | PMID:19570022 | PMID:19652710 | PMID:19682070 |
| PMID:19717510 | PMID:19767732 | PMID:19805629 | PMID:19812205 | PMID:19918053 | PMID:20007545 | PMID:20023662 | PMID:20070863 | PMID:20071520 | PMID:20113349 | PMID:20348425 | PMID:20393140 |
| PMID:20477948 | PMID:20488797 | PMID:20508067 | PMID:20508069 | PMID:20522787 | PMID:20529664 | PMID:20563595 | PMID:20639492 | PMID:20643770 | PMID:20645413 | PMID:20709956 | PMID:20722629 |
| PMID:20739479 | PMID:20805478 | PMID:20813842 | PMID:20829501 | PMID:20947763 | PMID:20975043 | PMID:21059855 | PMID:21059925 | PMID:21081501 | PMID:21102458 | PMID:21237152 | PMID:21266468 |
| PMID:21267068 | PMID:21278344 | PMID:21289095 | PMID:21292765 | PMID:21311565 | PMID:21357533 | PMID:21357538 | PMID:21474346 | PMID:21478880 | PMID:21505260 | PMID:21508259 | PMID:21518438 |
| PMID:21533069 | PMID:21602824 | PMID:21621419 | PMID:21651910 | PMID:21664437 | PMID:21670495 | PMID:21675966 | PMID:21677750 | PMID:21697458 | PMID:21698237 | PMID:21703403 | PMID:21747211 |
| PMID:21794079 | PMID:21812012 | PMID:21819958 | PMID:21821797 | PMID:21830236 | PMID:21838754 | PMID:21856950 | PMID:21865551 | PMID:21873635 | PMID:21915284 | PMID:21941410 | PMID:21982752 |
| PMID:21983632 | PMID:22002608 | PMID:22022466 | PMID:22101787 | PMID:22120528 | PMID:22185840 | PMID:22198387 | PMID:22235111 | PMID:22243662 | PMID:22248690 | PMID:22253851 | PMID:22275804 |
| PMID:22343416 | PMID:22349510 | PMID:22383490 | PMID:22387558 | PMID:22405772 | PMID:22415881 | PMID:22426419 | PMID:22447075 | PMID:22451435 | PMID:22490780 | PMID:22496641 | PMID:22529194 |
| PMID:22553206 | PMID:22558229 | PMID:22564028 | PMID:22585038 | PMID:22586114 | PMID:22649196 | PMID:22753929 | PMID:22781627 | PMID:22789015 | PMID:22797941 | PMID:22815977 | PMID:22848454 |
| PMID:22859404 | PMID:22875784 | PMID:22891241 | PMID:22915101 | PMID:22934234 | PMID:22948816 | PMID:22981536 | PMID:22984079 | PMID:22987361 | PMID:22988022 | PMID:22988253 | PMID:23017058 |
| PMID:23050672 | PMID:23089744 | PMID:23139414 | PMID:23143333 | PMID:23225887 | PMID:23250993 | PMID:23251531 | PMID:23267025 | PMID:23284663 | PMID:23284917 | PMID:23308196 | PMID:23315496 |
| PMID:23428419 | PMID:23454767 | PMID:23479225 | PMID:23489421 | PMID:23540405 | PMID:23562658 | PMID:23575529 | PMID:23583008 | PMID:23589615 | PMID:23613968 | PMID:23657251 | PMID:23689980 |
| PMID:23708969 | PMID:23711511 | PMID:23727220 | PMID:23736299 | PMID:23770338 | PMID:23805233 | PMID:23826152 | PMID:23830920 | PMID:23843215 | PMID:23867818 | PMID:23911869 | PMID:23940597 |
| PMID:23958305 | PMID:24091672 | PMID:24114535 | PMID:24157462 | PMID:24157968 | PMID:24194600 | PMID:24218483 | PMID:24222214 | PMID:24247209 | PMID:24453977 | PMID:24458711 | PMID:24470356 |
| PMID:24489101 | PMID:24590064 | PMID:24610121 | PMID:24651438 | PMID:24661878 | PMID:24694658 | PMID:24726878 | PMID:24729618 | PMID:24743022 | PMID:24798220 | PMID:24830427 | PMID:24879505 |
| PMID:24895290 | PMID:24922070 | PMID:24925032 | PMID:24941004 | PMID:24952961 | PMID:24991816 | PMID:25048544 | PMID:25127469 | PMID:25155463 | PMID:25170954 | PMID:25225402 | PMID:25239372 |
| PMID:25281740 | PMID:25310682 | PMID:25318104 | PMID:25343479 | PMID:25451844 | PMID:25464855 | PMID:25486274 | PMID:25502294 | PMID:25542352 | PMID:25542768 | PMID:25542861 | PMID:25564520 |
| PMID:25588875 | PMID:25605289 | PMID:25651887 | PMID:25675986 | PMID:25681768 | PMID:25690658 | PMID:25692702 | PMID:25700737 | PMID:25719930 | PMID:25740510 | PMID:25772484 | PMID:25796110 |
| PMID:25862090 | PMID:25948251 | PMID:25972159 | PMID:25998681 | PMID:26053862 | PMID:26060214 | PMID:26068648 | PMID:26091541 | PMID:26122280 | PMID:26152185 | PMID:26198936 | PMID:26295445 |
| PMID:26358881 | PMID:26384545 | PMID:26461208 | PMID:26474534 | PMID:26483196 | PMID:26522449 | PMID:26529046 | PMID:26553756 | PMID:26556873 | PMID:26572062 | PMID:26592184 | PMID:26631939 |
| PMID:26739809 | PMID:26747786 | PMID:26812038 | PMID:26830892 | PMID:26877061 | PMID:26935289 | PMID:27048203 | PMID:27159053 | PMID:27206526 | PMID:27255725 | PMID:27287410 | PMID:27292635 |
| PMID:27322617 | PMID:27466191 | PMID:27544305 | PMID:27559003 | PMID:27559050 | PMID:27626380 | PMID:27663455 | PMID:27663621 | PMID:27666820 | PMID:27707719 | PMID:27730511 | PMID:27775097 |
| PMID:27810364 | PMID:27824163 | PMID:27833023 | PMID:27840225 | PMID:27858314 | PMID:27866341 | PMID:27881823 | PMID:27929040 | PMID:27966552 | PMID:28031477 | PMID:28063215 | PMID:28069296 |
| PMID:28089560 | PMID:28225814 | PMID:28244110 | PMID:28286160 | PMID:28297661 | PMID:28322086 | PMID:28351919 | PMID:28377486 | PMID:28428949 | PMID:28430869 | PMID:28495929 | PMID:28554875 |
| PMID:28597172 | PMID:28628761 | PMID:28633291 | PMID:28671696 | PMID:28687662 | PMID:28723547 | PMID:28798231 | PMID:28802645 | PMID:28859168 | PMID:28930866 | PMID:28992079 | PMID:29018292 |
| PMID:29044426 | PMID:29075178 | PMID:29079688 | PMID:29176737 | PMID:29222907 | PMID:29270247 | PMID:29279307 | PMID:29467297 | PMID:29472582 | PMID:29508376 | PMID:29616195 | PMID:29725032 |
| PMID:29750294 | PMID:29858571 | PMID:29870687 | PMID:29958799 | PMID:29973721 | PMID:30010623 | PMID:30065030 | PMID:30068016 | PMID:30074479 | PMID:30093975 | PMID:30098501 | PMID:30281537 |
| PMID:30383448 | PMID:30458799 | PMID:30552101 | PMID:30626694 | PMID:30653952 | PMID:30655308 | PMID:30683682 | PMID:30777922 | PMID:30892913 | PMID:30919410 | PMID:30926332 | PMID:30949163 |
| PMID:30952064 | PMID:30952430 | PMID:31019207 | PMID:31075901 | PMID:31091450 | PMID:31100367 | PMID:31102752 | PMID:31233552 | PMID:31249344 | PMID:31308092 | PMID:31376190 | PMID:31425346 |
| PMID:31445901 | PMID:31533918 | PMID:31676289 | PMID:31693933 | PMID:31699796 | PMID:31736956 | PMID:31934722 | PMID:31982429 | PMID:32049051 | PMID:32103010 | PMID:32286307 | PMID:32325033 |
| PMID:32358018 | PMID:32566102 | PMID:32699136 | PMID:32982684 | PMID:33135636 | PMID:33199725 |
Genomics
