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Gene: Cd59b (CD59b antigen) Mus musculus
Symbol: Cd59b
Name: CD59b antigen
Description: Predicted to have complement binding activity. Involved in negative regulation of activation of membrane attack complex. Localizes to the cell surface and plasma membrane. Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian cancer. Is expressed in blood; heart; liver; lung; and testis. Orthologous to human CD59 (CD59 molecule (CD59 blood group)); PARTICIPATES IN coagulation cascade pathway; complement system pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD59B glycoprotein; MAC-inhibitory protein; MAC-IP; MACIF; membrane attack complex inhibition factor; protectin
Homo sapiens (human) : CD59 (CD59 molecule (CD59 blood group))  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd59 (CD59 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd59 (CD59 molecule (CD59 blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : CD59 (CD59 molecule (CD59 blood group))
Canis lupus familiaris (dog) : CD59 (CD59 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd59 (CD59 molecule (CD59 blood group))
Sus scrofa (pig) : CD59 (CD59 molecule (CD59 blood group))
Chlorocebus sabaeus (green monkey) : CD59 (CD59 molecule (CD59 blood group))
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl2104,069,849 - 104,091,187 (+)Ensembl
GRCm382104,069,781 - 104,085,790 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372103,911,167 - 103,925,114 (+)NCBIGRCm37mm9NCBIm37
MGSCv362103,871,849 - 103,885,796 (+)NCBImm8
Cytogenetic Map2 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cd59b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615538
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.