Cd59b (CD59b antigen) - Rat Genome Database

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Gene: Cd59b (CD59b antigen) Mus musculus
Analyze
Symbol: Cd59b
Name: CD59b antigen
RGD ID: 1615538
MGI Page MGI
Description: Predicted to enable complement binding activity. Acts upstream of or within negative regulation of activation of membrane attack complex. Located in cell surface and plasma membrane. Is expressed in blood; heart; liver; lung; and testis. Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian cancer. Orthologous to human CD59 (CD59 molecule (CD59 blood group)).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CD59B glycoprotein; MAC-inhibitory protein; MAC-IP; MACIF; membrane attack complex inhibition factor; protectin
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,900,127 - 103,920,619 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,896,142 - 103,921,534 (+)EnsemblGRCm39 Ensembl
GRCm382104,069,781 - 104,085,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2104,069,849 - 104,091,187 (+)EnsemblGRCm38mm10GRCm38
MGSCv372103,911,167 - 103,925,114 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362103,871,849 - 103,885,796 (+)NCBIMGSCv36mm8
Cytogenetic Map2E2NCBI
cM Map254.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-alpha-phellandrene  (ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (ISO)
1,3-Propane sultone  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-naphthylamine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-nitroquinoline N-oxide  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
aristolochic acids  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorambucil  (ISO)
choline  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
ethidium  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
fenthion  (EXP)
fipronil  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
gallic acid  (ISO)
glafenine  (ISO)
glyphosate  (ISO)
hexachlorobenzene  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
melphalan  (ISO)
methidathion  (EXP)
methyl methanesulfonate  (ISO)
mitomycin C  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (EXP,ISO)
sulfasalazine  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
Thiotepa  (ISO)
trichloroethene  (EXP)
Triptolide  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Ascitic complement system in ovarian cancer. Bjorge L, etal., Br J Cancer. 2005 Mar 14;92(5):895-905.
2. Loss of CD59 expression in breast tumours correlates with poor survival. Madjd Z, etal., J Pathol. 2003 Aug;200(5):633-9.
3. Expression of complement regulatory proteins-CD 35, CD 46, CD 55, and CD 59-in benign and malignant endometrial tissue. Murray KP, etal., Gynecol Oncol. 2000 Feb;76(2):176-82.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. PSMD11, PTPRM and PTPRB as novel biomarkers of pancreatic cancer progression. Sahni S, etal., Biochim Biophys Acta Gen Subj. 2020 Nov;1864(11):129682. doi: 10.1016/j.bbagen.2020.129682. Epub 2020 Jul 12.
10. CD59 silencing via retrovirus-mediated RNA interference enhanced complement-mediated cell damage in ovary cancer. Shi XX, etal., Cell Mol Immunol. 2009 Feb;6(1):61-6.
11. The expression of CD59 in experimental allergic neuritis. Vedeler CA, etal., J Neurol Sci. 1999 Jun 1;165(2):154-9.
12. Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. Yao X and Verkman AS, Acta Neuropathol Commun. 2017 Feb 17;5(1):15. doi: 10.1186/s40478-017-0417-9.
Additional References at PubMed
PMID:10946279   PMID:11471050   PMID:11485913   PMID:12477932   PMID:12594949   PMID:12914820   PMID:14610273   PMID:15356114   PMID:16272280   PMID:16541098   PMID:18799693   PMID:19051264  
PMID:19229985   PMID:20212283   PMID:21252115   PMID:21873635   PMID:22019898   PMID:25993318   PMID:27098205   PMID:27729184  


Genomics

Comparative Map Data
Cd59b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,900,127 - 103,920,619 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,896,142 - 103,921,534 (+)EnsemblGRCm39 Ensembl
GRCm382104,069,781 - 104,085,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2104,069,849 - 104,091,187 (+)EnsemblGRCm38mm10GRCm38
MGSCv372103,911,167 - 103,925,114 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362103,871,849 - 103,885,796 (+)NCBIMGSCv36mm8
Cytogenetic Map2E2NCBI
cM Map254.51NCBI
CD59
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381133,703,010 - 33,736,479 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1133,703,010 - 33,736,479 (-)EnsemblGRCh38hg38GRCh38
GRCh371133,724,556 - 33,758,025 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361133,681,132 - 33,714,600 (-)NCBINCBI36Build 36hg18NCBI36
Build 341133,681,133 - 33,714,600NCBI
Celera1133,872,059 - 33,905,528 (-)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1133,421,201 - 33,454,193 (-)NCBIHuRef
CHM1_11133,724,069 - 33,757,538 (-)NCBICHM1_1
T2T-CHM13v2.01133,840,023 - 33,873,492 (-)NCBIT2T-CHM13v2.0
Cd59b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,914,008 - 110,932,489 (+)NCBIGRCr8
mRatBN7.2390,459,085 - 90,477,571 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl390,459,162 - 90,478,847 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx393,952,281 - 93,970,470 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03102,551,356 - 102,569,545 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03100,381,722 - 100,399,939 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0394,010,481 - 94,028,660 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl394,010,475 - 94,028,621 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03100,650,411 - 100,668,036 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4389,243,600 - 89,245,129 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1389,318,629 - 89,333,534 (-)NCBI
Celera389,520,423 - 89,538,310 (+)NCBICelera
Cytogenetic Map3q32NCBI
Cd59
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542212,500,572 - 12,528,738 (+)NCBIChiLan1.0ChiLan1.0
CD59
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2935,924,653 - 35,961,425 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11135,929,328 - 35,965,188 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,680,580 - 33,708,479 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,558,898 - 33,590,156 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,552,164 - 33,590,157 (-)Ensemblpanpan1.1panPan2
CD59
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11833,977,433 - 33,999,145 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1833,977,480 - 33,998,329 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1833,582,994 - 33,604,719 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01834,588,535 - 34,610,237 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1834,588,574 - 34,610,237 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11834,147,266 - 34,158,335 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01833,740,409 - 33,762,219 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01834,376,094 - 34,397,903 (+)NCBIUU_Cfam_GSD_1.0
Cd59
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494731,117,789 - 31,137,338 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365334,242,589 - 4,263,136 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD59
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1227,186,587 - 27,207,303 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2229,777,121 - 29,797,735 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD59
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1131,547,876 - 31,571,720 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl131,547,937 - 31,570,835 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038128,644,490 - 128,668,102 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Cd59b
557 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1084
Count of miRNA genes:438
Interacting mature miRNAs:484
Transcripts:ENSMUST00000090429, ENSMUST00000111130, ENSMUST00000111131, ENSMUST00000111132, ENSMUST00000129749
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
4141448Mpaps1_mmicrophthalmia anophthalmia susceptibility 1 (mouse)Not determined97028557112115196Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse

Markers in Region
UniSTS:234477  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382104,084,909 - 104,085,041UniSTSGRCm38
GRCm382104,114,448 - 104,114,580UniSTSGRCm38
MGSCv372103,954,605 - 103,954,737UniSTSGRCm37
MGSCv372103,925,066 - 103,925,198UniSTSGRCm37
Cytogenetic Map2E2UniSTS
Rara  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4C3UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map2E2UniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map11B4UniSTS
Cytogenetic Map11D-E1UniSTS
Cytogenetic MapXA7.2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map13A1UniSTS
Cytogenetic Map17B2UniSTS
cM Map1157.8UniSTS
Cd59a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
Cd59a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
Cd59a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map254.51UniSTS
Cd59a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
Cd59b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001368215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_181858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF292401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC139203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC171969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX640578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX813317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000090429   ⟹   ENSMUSP00000087912
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,901,355 - 103,915,302 (+)Ensembl
GRCm38.p6 Ensembl2104,071,010 - 104,084,957 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111130   ⟹   ENSMUSP00000106760
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,901,411 - 103,915,165 (+)Ensembl
GRCm38.p6 Ensembl2104,071,066 - 104,084,820 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111131   ⟹   ENSMUSP00000106761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,900,194 - 103,921,505 (+)Ensembl
GRCm38.p6 Ensembl2104,069,849 - 104,091,160 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111132   ⟹   ENSMUSP00000106762
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,900,194 - 103,921,532 (+)Ensembl
GRCm38.p6 Ensembl2104,069,849 - 104,091,187 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129749   ⟹   ENSMUSP00000117553
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,900,138 - 103,915,979 (+)Ensembl
GRCm38.p6 Ensembl2104,069,891 - 104,084,645 (+)Ensembl
RefSeq Acc Id: ENSMUST00000238272
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,896,142 - 103,897,831 (+)Ensembl
RefSeq Acc Id: ENSMUST00000249333   ⟹   ENSMUSP00000159702
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,897,670 - 103,921,534 (+)Ensembl
RefSeq Acc Id: NM_001368215   ⟹   NP_001355144
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,901,411 - 103,915,165 (+)NCBI
GRCm382104,071,066 - 104,084,820 (+)NCBI
Sequence:
RefSeq Acc Id: NM_181858   ⟹   NP_862906
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,901,411 - 103,915,165 (+)NCBI
GRCm382104,071,066 - 104,084,820 (+)NCBI
MGSCv372103,911,167 - 103,925,114 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006499801   ⟹   XP_006499864
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,901,205 - 103,915,940 (+)NCBI
GRCm382104,070,860 - 104,085,595 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006499802   ⟹   XP_006499865
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,900,127 - 103,916,135 (+)NCBI
GRCm382104,069,781 - 104,085,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006499803   ⟹   XP_006499866
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,908,291 - 103,916,135 (+)NCBI
GRCm382104,077,945 - 104,085,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006499805   ⟹   XP_006499868
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,900,330 - 103,916,135 (+)NCBI
GRCm382104,069,985 - 104,085,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017319062   ⟹   XP_017174551
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,901,461 - 103,916,135 (+)NCBI
GRCm382104,071,116 - 104,085,790 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162337   ⟹   XP_036018230
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,901,463 - 103,920,619 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_862906   ⟸   NM_181858
- Peptide Label: precursor
- UniProtKB: Q920G7 (UniProtKB/Swiss-Prot),   P58019 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006499865   ⟸   XM_006499802
- Peptide Label: isoform X4
- UniProtKB: Q920G7 (UniProtKB/Swiss-Prot),   P58019 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006499868   ⟸   XM_006499805
- Peptide Label: isoform X4
- UniProtKB: Q920G7 (UniProtKB/Swiss-Prot),   P58019 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006499864   ⟸   XM_006499801
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006499866   ⟸   XM_006499803
- Peptide Label: isoform X4
- UniProtKB: Q920G7 (UniProtKB/Swiss-Prot),   P58019 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017174551   ⟸   XM_017319062
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001355144   ⟸   NM_001368215
- Peptide Label: precursor
- UniProtKB: P58019 (UniProtKB/Swiss-Prot),   Q920G7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000106762   ⟸   ENSMUST00000111132
RefSeq Acc Id: ENSMUSP00000106760   ⟸   ENSMUST00000111130
RefSeq Acc Id: ENSMUSP00000106761   ⟸   ENSMUST00000111131
RefSeq Acc Id: ENSMUSP00000087912   ⟸   ENSMUST00000090429
RefSeq Acc Id: ENSMUSP00000117553   ⟸   ENSMUST00000129749
RefSeq Acc Id: XP_036018230   ⟸   XM_036162337
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000159702   ⟸   ENSMUST00000249333
Protein Domains
UPAR/Ly6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P58019-F1-model_v2 AlphaFold P58019 1-129 view protein structure

Promoters
RGD ID:6830984
Promoter ID:MM_KWN:30817
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney
Transcripts:ENSMUST00000111130,   UC008LJL.1,   UC008LJM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362103,909,751 - 103,910,251 (+)MPROMDB
RGD ID:6878094
Promoter ID:EPDNEW_M2498
Type:multiple initiation site
Name:Cd59b_1
Description:Mus musculus CD59b antigen , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382104,069,849 - 104,069,909EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1888996 AgrOrtholog
Ensembl Genes ENSMUSG00000068686 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000090429 ENTREZGENE
  ENSMUST00000090429.8 UniProtKB/Swiss-Prot
  ENSMUST00000111130 ENTREZGENE
  ENSMUST00000111130.3 UniProtKB/Swiss-Prot
  ENSMUST00000111131.9 UniProtKB/TrEMBL
  ENSMUST00000111132.8 UniProtKB/TrEMBL
  ENSMUST00000129749 ENTREZGENE
  ENSMUST00000129749.9 UniProtKB/Swiss-Prot
  ENSMUST00000249333.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro LY6_UPA_recep-like UniProtKB/Swiss-Prot
  Snake_toxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:333883 UniProtKB/Swiss-Prot
MGD MGI:1888996 ENTREZGENE
NCBI Gene 333883 ENTREZGENE
PANTHER CD59 GLYCOPROTEIN UniProtKB/Swiss-Prot
  CD59 GLYCOPROTEIN UniProtKB/Swiss-Prot
PhenoGen Cd59b PhenoGen
SMART SM00134 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57302 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2BI28_MOUSE UniProtKB/TrEMBL
  CD59B_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q6PBG1_MOUSE UniProtKB/TrEMBL
  Q920G7 ENTREZGENE
UniProt Secondary Q920G7 UniProtKB/Swiss-Prot