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Gene: Atp1a2 (ATPase, Na+/K+ transporting, alpha 2 polypeptide) Mus musculus
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Symbol: Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Description: Predicted to contribute to ATP binding activity; ATPase activity; and alkali metal ion binding activity. Involved in several processes, including forebrain development; regulation of blood circulation; and regulation of muscle contraction. Localizes to T-tubule; cell projection; and neuronal cell body. Is expressed in several structures, including genitourinary system; heart; musculature; nervous system; and sensory organ. Used to study familial hemiplegic migraine. Human ortholog(s) of this gene implicated in alternating hemiplegia of childhood; benign neonatal seizures; familial hemiplegic migraine 2; hypertension; and migraine with aura. Orthologous to human ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Atpa-3; AW060654; mKIAA0778; Na(+)/K(+) ATPase alpha(+) subunit; Na(+)/K(+) ATPase alpha-2 subunit; sodium pump subunit alpha-2; sodium/potassium-transporting ATPase subunit alpha-2
Orthologs:
Homo sapiens (human) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atp1a2 (ATPase Na+/K+ transporting subunit alpha 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp1a2 (ATPase Na+/K+ transporting subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966570 (sodium/potassium-transporting ATPase subunit alpha-2)
Sus scrofa (pig) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)
Chlorocebus sabaeus (African green monkey) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1172,271,709 - 172,298,064 (-)EnsemblGRCm38mm10GRCm38
GRCm381172,271,709 - 172,298,064 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371174,201,840 - 174,228,195 (-)NCBIGRCm37mm9NCBIm37
MGSCv361174,108,384 - 174,134,739 (-)NCBImm8
Celera1175,123,792 - 175,151,771 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Atp1a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10206
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.