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Gene: Atp1a2 (ATPase, Na+/K+ transporting, alpha 2 polypeptide) Mus musculus
Symbol: Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Description: Predicted to contribute to ATP binding activity; ATPase activity; and alkali metal ion binding activity. Involved in several processes, including forebrain development; regulation of blood circulation; and regulation of muscle contraction. Localizes to T-tubule; cell projection; and neuronal cell body. Is expressed in several structures, including genitourinary system; heart; musculature; nervous system; and sensory organ. Used to study familial hemiplegic migraine. Human ortholog(s) of this gene implicated in alternating hemiplegia of childhood; benign neonatal seizures; familial hemiplegic migraine 2; hypertension; and migraine with aura. Orthologous to human ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Atpa-3; AW060654; mKIAA0778; Na(+)/K(+) ATPase alpha(+) subunit; Na(+)/K(+) ATPase alpha-2 subunit; sodium pump subunit alpha-2; sodium/potassium-transporting ATPase subunit alpha-2
Homo sapiens (human) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atp1a2 (ATPase Na+/K+ transporting subunit alpha 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp1a2 (ATPase Na+/K+ transporting subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966570 (sodium/potassium-transporting ATPase subunit alpha-2)
Sus scrofa (pig) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)
Chlorocebus sabaeus (African green monkey) : ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1172,271,709 - 172,298,064 (-)EnsemblGRCm38mm10GRCm38
GRCm381172,271,709 - 172,298,064 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371174,201,840 - 174,228,195 (-)NCBIGRCm37mm9NCBIm37
MGSCv361174,108,384 - 174,134,739 (-)NCBImm8
Celera1175,123,792 - 175,151,771 (-)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atp1a2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10206
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.