(+)-schisandrin B multiple interactions ISO Flnc (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of FLNC mRNA] CTD PMID:31150632 1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of FLNC mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression ISO Flnc (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of FLNC mRNA CTD PMID:30723492 17beta-estradiol decreases expression ISO FLNC (Homo sapiens) 6480464 Estradiol results in decreased expression of FLNC mRNA CTD PMID:16514628 17beta-estradiol multiple interactions ISO FLNC (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of FLNC mRNA and Estradiol promotes the reaction [FLNC protein binds to ESR1 protein] CTD PMID:27156127 and PMID:30165855 2,3',4,4',5-Pentachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Flnc (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of FLNC mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Flnc (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of FLNC mRNA CTD PMID:33387578 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Flnc (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO FLNC (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of FLNC mRNA CTD PMID:28628672 3H-1,2-dithiole-3-thione increases expression ISO Flnc (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in increased expression of FLNC mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of FLNC mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol decreases methylation ISO FLNC (Homo sapiens) 6480464 bisphenol S results in decreased methylation of FLNC gene CTD PMID:31601247 4,4'-sulfonyldiphenol increases methylation EXP 6480464 bisphenol S results in increased methylation of FLNC exon CTD PMID:33297965 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of FLNC mRNA CTD PMID:30951980 7,12-dimethyltetraphene increases expression ISO FLNC (Homo sapiens) 6480464 9 more ... CTD PMID:21527772 actinomycin D increases expression ISO FLNC (Homo sapiens) 6480464 Dactinomycin results in increased expression of FLNC mRNA CTD PMID:21527772 afimoxifene decreases expression ISO FLNC (Homo sapiens) 6480464 afimoxifene results in decreased expression of FLNC mRNA CTD PMID:16514628 aflatoxin B1 increases expression ISO FLNC (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of FLNC mRNA CTD PMID:21527772 and PMID:27153756 aflatoxin B1 increases methylation ISO FLNC (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of FLNC exon CTD PMID:30157460 all-trans-retinoic acid multiple interactions EXP 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of FLNC mRNA and [bisphenol S co-treated with Tretinoin] results in decreased expression of FLNC mRNA CTD PMID:30951980 antirheumatic drug increases expression ISO FLNC (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of FLNC mRNA CTD PMID:24449571 aristolochic acid A increases expression ISO FLNC (Homo sapiens) 6480464 aristolochic acid I results in increased expression of FLNC mRNA CTD PMID:33212167 arsenite(3-) multiple interactions ISO FLNC (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to FLNC mRNA] CTD PMID:32406909 atrazine decreases expression ISO Flnc (Rattus norvegicus) 6480464 Atrazine results in decreased expression of FLNC mRNA CTD PMID:36841081 benzo[a]pyrene increases mutagenesis ISO FLNC (Homo sapiens) 6480464 Benzo(a)pyrene results in increased mutagenesis of FLNC gene CTD PMID:25435355 benzo[a]pyrene decreases expression ISO FLNC (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of FLNC mRNA CTD PMID:32234424 benzo[a]pyrene affects methylation ISO FLNC (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of FLNC exon CTD PMID:30157460 benzo[a]pyrene decreases methylation ISO FLNC (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of FLNC 3' UTR and Benzo(a)pyrene results in decreased methylation of FLNC promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO FLNC (Homo sapiens) 6480464 [Soot co-treated with Benzo(a)pyrene] results in increased expression of FLNC protein CTD PMID:24464499 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of FLNC mRNA CTD PMID:22610609 beta-naphthoflavone increases expression ISO FLNC (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of FLNC mRNA CTD PMID:19737606 bis(2-chloroethyl) sulfide increases expression ISO FLNC (Homo sapiens) 6480464 Mustard Gas results in increased expression of FLNC mRNA CTD PMID:25102026 bis(2-ethylhexyl) phthalate increases expression ISO FLNC (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of FLNC mRNA CTD PMID:31163220 bisphenol A increases expression ISO Flnc (Rattus norvegicus) 6480464 bisphenol A results in increased expression of FLNC mRNA CTD PMID:25181051 and PMID:30816183 bisphenol A increases expression ISO FLNC (Homo sapiens) 6480464 bisphenol A results in increased expression of FLNC protein CTD PMID:37567409 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of FLNC mRNA CTD PMID:32156529 and PMID:37392660 bisphenol A multiple interactions ISO FLNC (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of FLNC gene CTD PMID:31601247 bisphenol A affects methylation ISO FLNC (Homo sapiens) 6480464 bisphenol A affects the methylation of FLNC gene CTD PMID:31601247 bisphenol A affects expression ISO FLNC (Homo sapiens) 6480464 bisphenol A affects the expression of FLNC protein CTD PMID:34186270 bisphenol A decreases expression ISO FLNC (Homo sapiens) 6480464 bisphenol A results in decreased expression of FLNC protein CTD PMID:33024228 bisphenol A affects expression ISO Flnc (Rattus norvegicus) 6480464 bisphenol A affects the expression of FLNC mRNA CTD PMID:32145629 bisphenol A decreases expression ISO Flnc (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of FLNC mRNA CTD PMID:33296240 and PMID:34947998 Bisphenol B increases expression ISO FLNC (Homo sapiens) 6480464 bisphenol B results in increased expression of FLNC protein CTD PMID:34186270 bisphenol F multiple interactions ISO FLNC (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of FLNC mRNA CTD PMID:28628672 bisphenol F increases expression ISO FLNC (Homo sapiens) 6480464 bisphenol F results in increased expression of FLNC protein CTD PMID:34186270 bisphenol F multiple interactions EXP 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of FLNC mRNA CTD PMID:30951980 cadmium dichloride increases expression ISO FLNC (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of FLNC protein CTD PMID:24527689 calcitriol decreases expression ISO FLNC (Homo sapiens) 6480464 Calcitriol results in decreased expression of FLNC mRNA CTD PMID:26485663 cannabidiol multiple interactions ISO FLNC (Homo sapiens) 6480464 [Cuprizone co-treated with Cannabidiol] results in decreased expression of FLNC protein CTD PMID:34122009 cantharidin decreases expression EXP 6480464 Cantharidin results in decreased expression of FLNC mRNA CTD PMID:36907384 carbamazepine affects expression ISO FLNC (Homo sapiens) 6480464 Carbamazepine affects the expression of FLNC mRNA CTD PMID:25979313 carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of FLNC mRNA CTD PMID:25554681 chlordecone increases expression EXP 6480464 Chlordecone results in increased expression of FLNC mRNA CTD PMID:33711761 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FLNC mRNA CTD PMID:20938992 ciglitazone increases expression ISO Flnc (Rattus norvegicus) 6480464 ciglitazone results in increased expression of FLNC mRNA CTD PMID:22193206 cisplatin decreases expression ISO Flnc (Rattus norvegicus) 6480464 Cisplatin results in decreased expression of FLNC mRNA CTD PMID:22023808 cobalt dichloride increases expression ISO FLNC (Homo sapiens) 6480464 cobaltous chloride results in increased expression of FLNC mRNA CTD PMID:19320972 copper atom multiple interactions ISO FLNC (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of FLNC mRNA and [NSC 689534 binds to Copper] which results in increased expression of FLNC mRNA CTD PMID:20971185 and PMID:30911355 copper(0) multiple interactions ISO FLNC (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of FLNC mRNA and [NSC 689534 binds to Copper] which results in increased expression of FLNC mRNA CTD PMID:20971185 and PMID:30911355 copper(II) sulfate affects expression ISO FLNC (Homo sapiens) 6480464 Copper Sulfate affects the expression of FLNC mRNA CTD PMID:19549813 Cuprizon decreases expression ISO Flnc (Rattus norvegicus) 6480464 Cuprizone results in decreased expression of FLNC mRNA CTD PMID:27523638 Cuprizon increases expression ISO FLNC (Homo sapiens) 6480464 Cuprizone results in increased expression of FLNC protein CTD PMID:34122009 Cuprizon multiple interactions ISO FLNC (Homo sapiens) 6480464 [Cuprizone co-treated with Cannabidiol] results in decreased expression of FLNC protein CTD PMID:34122009 cyclophosphamide increases expression ISO FLNC (Homo sapiens) 6480464 Cyclophosphamide results in increased expression of FLNC mRNA CTD PMID:21527772 cytarabine decreases expression ISO FLNC (Homo sapiens) 6480464 Cytarabine results in decreased expression of FLNC mRNA CTD PMID:21198554 dexamethasone multiple interactions ISO FLNC (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of FLNC mRNA CTD PMID:28628672 Didecyldimethylammonium decreases expression ISO FLNC (Homo sapiens) 6480464 didecyldimethylammonium results in decreased expression of FLNC mRNA CTD PMID:32763356 dimethyl sulfoxide increases expression ISO Flnc (Rattus norvegicus) 6480464 Dimethyl Sulfoxide results in increased expression of FLNC mRNA CTD PMID:22193206 dimethylarsinic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FLNC mRNA CTD PMID:34876320 dimethylselenide multiple interactions ISO FLNC (Homo sapiens) 6480464 [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of FLNC-AS1 mRNA] which results in increased expression of FLNC mRNA and [[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of FLNC-AS1 mRNA] which results in increased expression of FLNC mRNA CTD PMID:33656867 dioxygen multiple interactions ISO Flnc (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of FLNC mRNA CTD PMID:33729688 dorsomorphin multiple interactions ISO FLNC (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FLNC mRNA CTD PMID:27188386 doxorubicin increases expression ISO FLNC (Homo sapiens) 6480464 Doxorubicin results in increased expression of FLNC mRNA CTD PMID:29803840 endosulfan increases expression ISO Flnc (Rattus norvegicus) 6480464 Endosulfan results in increased expression of FLNC mRNA CTD PMID:29391264 ethanol multiple interactions ISO Flnc (Rattus norvegicus) 6480464 [Fish Oils co-treated with Ethanol] results in increased expression of FLNC mRNA CTD PMID:17347304 ethylparaben increases expression ISO FLNC (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in increased expression of FLNC mRNA CTD PMID:37690743 etoposide increases expression ISO FLNC (Homo sapiens) 6480464 Etoposide results in increased expression of FLNC mRNA CTD PMID:21527772 fenamidone increases expression EXP 6480464 fenamidone results in increased expression of FLNC mRNA CTD PMID:27029645 fenvalerate increases expression ISO Flnc (Rattus norvegicus) 6480464 fenvalerate results in increased expression of FLNC mRNA CTD PMID:30307764 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FLNC mRNA CTD PMID:20938992 FR900359 affects phosphorylation ISO FLNC (Homo sapiens) 6480464 FR900359 affects the phosphorylation of FLNC protein CTD PMID:37730182 fulvestrant decreases expression ISO FLNC (Homo sapiens) 6480464 fulvestrant results in decreased expression of FLNC mRNA CTD PMID:16514628 fulvestrant multiple interactions ISO FLNC (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of FLNC gene CTD PMID:31601247 fulvestrant decreases methylation ISO FLNC (Homo sapiens) 6480464 Fulvestrant results in decreased methylation of FLNC gene CTD PMID:31601247 furan increases expression ISO Flnc (Rattus norvegicus) 6480464 furan results in increased expression of FLNC mRNA CTD PMID:27387713 hydrogen peroxide multiple interactions EXP 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5 more ... CTD PMID:31494107 hydroxyl multiple interactions ISO FLNC (Homo sapiens) 6480464 [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of FLNC-AS1 mRNA] which results in increased expression of FLNC mRNA CTD PMID:33656867 indometacin multiple interactions ISO FLNC (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of FLNC mRNA CTD PMID:28628672 ivermectin decreases expression ISO FLNC (Homo sapiens) 6480464 Ivermectin results in decreased expression of FLNC protein CTD PMID:32959892 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FLNC mRNA CTD PMID:20938992 lidocaine increases expression ISO Flnc (Rattus norvegicus) 6480464 Lidocaine results in increased expression of FLNC mRNA CTD PMID:35283115 lipopolysaccharide multiple interactions ISO FLNC (Homo sapiens) 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of FLNC mRNA more ... CTD PMID:35811015 and PMID:35877022 mercury dibromide increases expression ISO FLNC (Homo sapiens) 6480464 mercuric bromide results in increased expression of FLNC mRNA CTD PMID:26272509 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of FLNC mRNA CTD PMID:26307267 and PMID:36914120 methylarsonic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FLNC mRNA CTD PMID:34876320 methylseleninic acid increases expression ISO FLNC (Homo sapiens) 6480464 methylselenic acid results in increased expression of FLNC mRNA CTD PMID:18548127 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FLNC mRNA CTD PMID:25566086 N-methyl-4-phenylpyridinium increases expression ISO FLNC (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of FLNC mRNA CTD PMID:24810058 nickel sulfate decreases expression ISO FLNC (Homo sapiens) 6480464 nickel sulfate results in decreased expression of FLNC mRNA CTD PMID:22714537 ozone multiple interactions ISO FLNC (Homo sapiens) 6480464 [[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of FLNC-AS1 mRNA] which results in increased expression of FLNC mRNA CTD PMID:33656867 paracetamol decreases expression ISO FLNC (Homo sapiens) 6480464 Acetaminophen results in decreased expression of FLNC mRNA CTD PMID:22230336 paracetamol decreases expression ISO Flnc (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of FLNC mRNA CTD PMID:33387578 paraquat increases expression ISO Flnc (Rattus norvegicus) 6480464 Paraquat results in increased expression of FLNC mRNA CTD PMID:32680482 phenylmercury acetate increases expression ISO FLNC (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of FLNC mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO FLNC (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FLNC mRNA CTD PMID:27188386 pioglitazone multiple interactions EXP 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FLNC mRNA CTD PMID:27935865 potassium chromate increases expression ISO FLNC (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of FLNC mRNA CTD PMID:22714537 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of FLNC mRNA CTD PMID:23608068 raloxifene decreases expression ISO FLNC (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased expression of FLNC mRNA CTD PMID:16514628 S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO FLNC (Homo sapiens) 6480464 S-(1 and 2-dichlorovinyl)cysteine results in increased expression of FLNC mRNA CTD PMID:35811015 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO FLNC (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 SB 431542 multiple interactions ISO FLNC (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:37664457 silicon dioxide decreases expression ISO Flnc (Rattus norvegicus) 6480464 Silicon Dioxide results in decreased expression of FLNC mRNA CTD PMID:32721576 silver atom increases expression ISO FLNC (Homo sapiens) 6480464 Silver results in increased expression of FLNC mRNA CTD PMID:28959546 silver(0) increases expression ISO FLNC (Homo sapiens) 6480464 Silver results in increased expression of FLNC mRNA CTD PMID:28959546 sodium arsenate multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FLNC mRNA CTD PMID:34876320 sodium arsenite decreases expression ISO Flnc (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of FLNC protein CTD PMID:29459688 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of FLNC mRNA CTD PMID:37682722 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of FLNC mRNA CTD PMID:36209798 sodium arsenite multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FLNC mRNA CTD PMID:34876320 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of FLNC protein CTD PMID:28918527 Soman increases expression ISO Flnc (Rattus norvegicus) 6480464 Soman results in increased expression of FLNC mRNA CTD PMID:19281266 sotorasib multiple interactions ISO FLNC (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FLNC mRNA CTD PMID:36139627 sunitinib increases expression ISO FLNC (Homo sapiens) 6480464 Sunitinib results in increased expression of FLNC mRNA CTD PMID:31533062 tamoxifen affects expression ISO FLNC (Homo sapiens) 6480464 Tamoxifen affects the expression of FLNC mRNA CTD PMID:14699072 temozolomide decreases expression ISO FLNC (Homo sapiens) 6480464 Temozolomide results in decreased expression of FLNC mRNA CTD PMID:31758290 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of FLNC mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO Flnc (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of FLNC mRNA] CTD PMID:31150632 tetrachloromethane increases expression ISO Flnc (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of FLNC mRNA CTD PMID:31150632 thioacetamide increases expression ISO Flnc (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of FLNC mRNA CTD PMID:34492290 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of FLNC mRNA CTD PMID:23557971 topotecan affects response to substance ISO FLNC (Homo sapiens) 6480464 FLNC protein affects the susceptibility to Topotecan CTD PMID:16217747 trametinib multiple interactions ISO FLNC (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of FLNC mRNA CTD PMID:36139627 valproic acid increases expression ISO FLNC (Homo sapiens) 6480464 Valproic Acid results in increased expression of FLNC mRNA CTD PMID:23179753 more ... valproic acid increases methylation ISO FLNC (Homo sapiens) 6480464 Valproic Acid results in increased methylation of FLNC gene CTD PMID:29154799