Irgm1 (immunity-related GTPase family M member 1) - Rat Genome Database

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Gene: Irgm1 (immunity-related GTPase family M member 1) Mus musculus
Analyze
Symbol: Irgm1
Name: immunity-related GTPase family M member 1
RGD ID: 1621624
MGI Page MGI
Description: Enables GTPase activity and anion binding activity. Involved in several processes, including macroautophagy; positive regulation of macroautophagy; and regulation of defense response. Acts upstream of or within cellular response to type II interferon and response to bacterium. Located in autolysosome; late endosome; and phagocytic vesicle. Is active in Golgi membrane; lysosomal membrane; and mitochondrial membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in inflammatory bowel disease 19 and tuberculosis. Orthologous to human IRGM (immunity related GTPase M).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: If; Ifggd3; Ifi1; Ii; Iigp3; Iipg3; immunity related GTPase m1; immunity-related GTPase family M protein; immunity-related GTPase family M protein 1; immunity-related GTPase family, M; interferon inducible protein 1; interferon-gamma-inducible GTPase Ifggd3 protein; interferon-inducible GTPase 3; interferon-inducible protein 1; Ir; Irgm; LPS-stimulated RAW 264.7 macrophage protein 47; LRG-; LRG-47
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391148,756,072 - 48,762,247 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1148,752,795 - 48,762,510 (-)EnsemblGRCm39 Ensembl
GRCm381148,865,245 - 48,871,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1148,861,968 - 48,871,683 (-)EnsemblGRCm38mm10GRCm38
MGSCv371148,678,751 - 48,684,848 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361148,708,672 - 48,714,769 (-)NCBIMGSCv36mm8
Celera1153,447,611 - 53,453,702 (-)NCBICelera
Cytogenetic Map11B1.2NCBI
cM Map1128.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-alpha-phellandrene  (ISO)
1,2-dimethylhydrazine  (EXP)
15-acetyldeoxynivalenol  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-nitrophenol  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP)
alpha-phellandrene  (ISO)
Aroclor 1254  (EXP)
Benoxacor  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buspirone  (ISO)
butanal  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (EXP)
chloroprene  (ISO)
ciguatoxin CTX1B  (EXP)
Cuprizon  (ISO)
cyclosporin A  (EXP)
D-glucose  (EXP)
dexamethasone  (EXP)
diclofenac  (EXP)
dieldrin  (ISO)
diethyl maleate  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
endosulfan  (ISO)
fluoranthene  (EXP)
flusilazole  (EXP)
flutamide  (ISO)
folic acid  (EXP)
fructose  (EXP)
gentamycin  (ISO)
ginsenoside Re  (ISO)
glucose  (EXP)
glyphosate  (EXP,ISO)
hexaconazole  (EXP)
indole-3-methanol  (ISO)
lipopolysaccharide  (EXP)
metam  (EXP)
nefazodone  (ISO)
nevirapine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
potassium dichromate  (EXP)
propanal  (ISO)
propiconazole  (EXP)
resveratrol  (EXP)
SB 203580  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP)
Soman  (ISO)
succimer  (EXP)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
triadimefon  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
trovafloxacin  (EXP)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
autophagosome assembly  (IBA,IDA,ISO)
autophagosome maturation  (IDA)
autophagy  (IEA)
CAMKK-AMPK signaling cascade  (ISO)
cellular response to interferon-beta  (IBA)
cellular response to lipopolysaccharide  (ISO)
cellular response to type II interferon  (IDA)
cellular response to virus  (ISO)
defense response  (IMP)
defense response to bacterium  (IDA,IMP,ISO)
defense response to Gram-negative bacterium  (ISO)
immune system process  (IEA)
innate immune response  (IBA,IDA,ISO)
negative regulation of canonical NF-kappaB signal transduction  (ISO)
negative regulation of cGAS/STING signaling pathway  (ISO)
negative regulation of defense response to virus  (IMP,ISO)
negative regulation of hematopoietic stem cell proliferation  (IMP)
negative regulation of inflammatory response  (IMP,ISO)
negative regulation of NLRP3 inflammasome complex assembly  (IDA,ISO)
negative regulation of type I interferon production  (IMP,ISO)
negative regulation of type II interferon production  (IMP)
nucleotide-binding oligomerization domain containing 2 signaling pathway  (ISO)
positive regulation of autophagosome maturation  (IDA,ISO)
positive regulation of autophagy  (IDA,IMP,ISO)
positive regulation of CD4-positive, alpha-beta T cell proliferation  (IMP)
positive regulation of lysosome organization  (ISO)
positive regulation of macrophage activation  (IMP)
positive regulation of mitochondrial fission  (ISO)
positive regulation of mitophagy  (IMP,ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of peptidyl-threonine phosphorylation  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of type II interferon-mediated signaling pathway  (IMP,ISO)
positive regulation of xenophagy  (ISO)
protein destabilization  (ISO)
protein stabilization  (ISO)
protein targeting to vacuole involved in autophagy  (ISO)
protein-containing complex assembly  (ISO)
regulation of mitochondrial fission  (IDA)
regulation of protein complex stability  (ISO)
regulation of protein-containing complex assembly  (ISO)
response to bacterium  (IEP)

References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7561525   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11457893   PMID:12466851   PMID:12477932   PMID:14576437   PMID:14707092   PMID:15294976   PMID:15908352  
PMID:16141072   PMID:16141073   PMID:16339555   PMID:16888103   PMID:17082622   PMID:17911638   PMID:17982087   PMID:18371424   PMID:18424746   PMID:18772884   PMID:18806793   PMID:19066452  
PMID:19120485   PMID:19144319   PMID:19176402   PMID:19620982   PMID:19920210   PMID:20056715   PMID:20072621   PMID:20566858   PMID:21383050   PMID:21633090   PMID:21731484   PMID:21757726  
PMID:21873635   PMID:22163006   PMID:22675202   PMID:22796503   PMID:22855710   PMID:22874556   PMID:22892676   PMID:22919646   PMID:23012479   PMID:23070814   PMID:23132496   PMID:23689639  
PMID:23785284   PMID:23842753   PMID:23853600   PMID:23989005   PMID:24715728   PMID:24751652   PMID:25356593   PMID:25482432   PMID:25619828   PMID:25628099   PMID:25644000   PMID:26202910  
PMID:26440898   PMID:26660918   PMID:26792178   PMID:27098192   PMID:27439214   PMID:27443879   PMID:28154172   PMID:28193861   PMID:29361512   PMID:29733654   PMID:30550785   PMID:30612879  
PMID:31612615   PMID:31648279   PMID:32311672   PMID:32376415   PMID:32453761   PMID:32542357   PMID:32715615   PMID:32968282   PMID:33124745   PMID:33510463   PMID:34078740   PMID:34338548  
PMID:34467632   PMID:34646375   PMID:34694641   PMID:35197566   PMID:35670107   PMID:35941154   PMID:36221902   PMID:36580725   PMID:36628446   PMID:37698925   PMID:37874678  


Genomics

Comparative Map Data
Irgm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391148,756,072 - 48,762,247 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1148,752,795 - 48,762,510 (-)EnsemblGRCm39 Ensembl
GRCm381148,865,245 - 48,871,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1148,861,968 - 48,871,683 (-)EnsemblGRCm38mm10GRCm38
MGSCv371148,678,751 - 48,684,848 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361148,708,672 - 48,714,769 (-)NCBIMGSCv36mm8
Celera1153,447,611 - 53,453,702 (-)NCBICelera
Cytogenetic Map11B1.2NCBI
cM Map1128.84NCBI
IRGM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385150,846,521 - 150,902,402 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5150,846,521 - 150,900,736 (+)EnsemblGRCh38hg38GRCh38
GRCh375150,226,083 - 150,281,964 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365150,207,879 - 150,208,424 (+)NCBINCBI36Build 36hg18NCBI36
Celera5146,307,411 - 146,309,557 (+)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5145,371,946 - 145,374,092 (+)NCBIHuRef
CHM1_15149,658,892 - 149,661,038 (+)NCBICHM1_1
T2T-CHM13v2.05151,383,019 - 151,438,900 (+)NCBIT2T-CHM13v2.0
Irgm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81033,734,640 - 33,742,720 (-)NCBIGRCr8
mRatBN7.21033,233,513 - 33,241,594 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1033,233,455 - 33,241,578 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1037,913,410 - 37,921,342 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0106,451,824 - 6,459,756 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01032,907,048 - 32,914,980 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01034,213,885 - 34,221,968 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1034,213,936 - 34,221,928 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01033,997,565 - 34,005,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41034,132,512 - 34,140,450 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11034,133,560 - 34,141,499 (-)NCBI
Celera1032,619,552 - 32,627,490 (-)NCBICelera
Cytogenetic Map10q21NCBI
Irgm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554082,338,510 - 2,344,566 (+)NCBIChiLan1.0ChiLan1.0
IRGM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24146,078,470 - 146,134,350 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15144,218,016 - 144,273,896 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05146,274,097 - 146,329,979 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15152,276,981 - 152,332,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5152,278,581 - 152,308,182 (+)Ensemblpanpan1.1panPan2
LOC606863
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.111506,981 - 523,338 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl11509,636 - 510,829 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha11568,312 - 569,505 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.011470,804 - 485,519 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.111443,994 - 445,187 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.011531,575 - 532,768 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.011692,999 - 694,192 (-)NCBIUU_Cfam_GSD_1.0
LOC101972667
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213142,480,944 - 142,493,084 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365044,055,091 - 4,056,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRGM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12353,449,576 - 53,451,373 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603424,239,475 - 24,271,349 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irgm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473341,241,488 - 41,248,162 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Irgm1
176 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:363
Count of miRNA genes:294
Interacting mature miRNAs:323
Transcripts:ENSMUST00000049519, ENSMUST00000097271, ENSMUST00000147151
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114277262654081064Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
13452402Hipmt3_mhippocampal morphometry trait 3 (mouse)114797732550277325Mouse

Markers in Region
U19119  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381148,865,590 - 48,865,741UniSTSGRCm38
MGSCv371148,679,092 - 48,679,243UniSTSGRCm37
Celera1153,447,952 - 53,448,103UniSTS
Cytogenetic Map11B1.2UniSTS
Whitehead_YAC11 UniSTS
Ifi1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381148,865,274 - 48,865,511UniSTSGRCm38
MGSCv371148,678,776 - 48,679,013UniSTSGRCm37
Celera1153,447,636 - 53,447,873UniSTS
Cytogenetic Map11B1.2UniSTS
cM Map11 UniSTS
cM MapUN UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001355757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK002545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX961862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY159883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ217401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU695230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FR734034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC541561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LT629149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LT629152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U19119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000049519   ⟹   ENSMUSP00000050446
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,756,072 - 48,762,201 (-)Ensembl
GRCm38.p6 Ensembl1148,865,245 - 48,871,374 (-)Ensembl
RefSeq Acc Id: ENSMUST00000097271   ⟹   ENSMUSP00000094870
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,756,076 - 48,762,247 (-)Ensembl
GRCm38.p6 Ensembl1148,865,249 - 48,871,420 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147151
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1148,752,795 - 48,762,510 (-)Ensembl
GRCm38.p6 Ensembl1148,861,968 - 48,871,683 (-)Ensembl
RefSeq Acc Id: NM_001355757   ⟹   NP_001342686
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391148,756,072 - 48,762,247 (-)NCBI
GRCm381148,865,245 - 48,871,420 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008326   ⟹   NP_032352
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391148,756,072 - 48,762,247 (-)NCBI
GRCm381148,865,245 - 48,871,420 (-)NCBI
MGSCv371148,678,751 - 48,684,848 (-)RGD
Celera1153,447,611 - 53,453,702 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011248764   ⟹   XP_011247066
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391148,756,072 - 48,758,919 (-)NCBI
GRCm381148,865,245 - 48,868,093 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030245596   ⟹   XP_030101456
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391148,756,072 - 48,762,215 (-)NCBI
GRCm381148,865,245 - 48,868,539 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032352   ⟸   NM_008326
- Peptide Label: isoform 1
- UniProtKB: Q3TJ73 (UniProtKB/Swiss-Prot),   Q60766 (UniProtKB/Swiss-Prot),   A0A1G5SJL2 (UniProtKB/TrEMBL),   A0A1G5SJJ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247066   ⟸   XM_011248764
- Peptide Label: isoform X1
- UniProtKB: J7NUP1 (UniProtKB/TrEMBL),   Q5NCB5 (UniProtKB/TrEMBL),   U5NJN6 (UniProtKB/TrEMBL),   V9PVS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001342686   ⟸   NM_001355757
- Peptide Label: isoform 2
- UniProtKB: Q5NCB5 (UniProtKB/TrEMBL),   U5NJN6 (UniProtKB/TrEMBL),   J7NUP1 (UniProtKB/TrEMBL),   V9PVS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030101456   ⟸   XM_030245596
- Peptide Label: isoform X1
- UniProtKB: Q5NCB5 (UniProtKB/TrEMBL),   U5NJN6 (UniProtKB/TrEMBL),   J7NUP1 (UniProtKB/TrEMBL),   V9PVS1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000050446   ⟸   ENSMUST00000049519
RefSeq Acc Id: ENSMUSP00000094870   ⟸   ENSMUST00000097271
Protein Domains
IRG-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q60766-F1-model_v2 AlphaFold Q60766 1-409 view protein structure

Promoters
RGD ID:6821117
Promoter ID:MM_KWN:7147
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000097271,   OTTMUST00000012269,   OTTMUST00000012270
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361148,684,766 - 48,685,897 (-)MPROMDB
RGD ID:8674456
Promoter ID:EPDNEW_M15250
Type:initiation region
Name:Irgm1_1
Description:Mus musculus immunity-related GTPase family M member 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381148,871,386 - 48,871,446EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107567 AgrOrtholog
Ensembl Genes ENSMUSG00000046879 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000049519 ENTREZGENE
  ENSMUST00000049519.4 UniProtKB/Swiss-Prot
  ENSMUST00000097271 ENTREZGENE
  ENSMUST00000097271.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro G_IRG_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunity-related_GTPase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15944 UniProtKB/Swiss-Prot
MGD MGI:107567 ENTREZGENE
NCBI Gene 15944 ENTREZGENE
PANTHER IMMUNITY-RELATED GTPASE FAMILY M PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  INTERFERON-INDUCIBLE GTPASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IIGP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Irgm1 PhenoGen
PROSITE G_IRG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1G5SJJ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A1G5SJL2 ENTREZGENE
  IRGM1_MOUSE UniProtKB/Swiss-Prot
  J7NUP1 ENTREZGENE, UniProtKB/TrEMBL
  Q3TJ73 ENTREZGENE
  Q5NCB5 ENTREZGENE
  Q60766 ENTREZGENE
  U5NJN6 ENTREZGENE
  V9PVS1 ENTREZGENE
UniProt Secondary Q3TJ73 UniProtKB/Swiss-Prot
  Q5NCB5 UniProtKB/TrEMBL