Dffa (DNA fragmentation factor, alpha subunit) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Dffa (DNA fragmentation factor, alpha subunit) Mus musculus
Analyze
Symbol: Dffa
Name: DNA fragmentation factor, alpha subunit
RGD ID: 734110
MGI Page MGI
Description: Predicted to enable deoxyribonuclease inhibitor activity; protein domain specific binding activity; and protein folding chaperone. Acts upstream of or within negative regulation of apoptotic DNA fragmentation; positive regulation of apoptotic process; and thymocyte apoptotic process. Predicted to be located in several cellular components, including chromatin; cytosol; and nucleus. Predicted to be part of protein-containing complex. Is expressed in several structures, including brain; heart; hemolymphoid system gland; liver; and metanephros. Orthologous to human DFFA (DNA fragmentation factor subunit alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A330085O09Rik; DFF-45; DFF35; Dff45; DNA fragmentation factor 45 kDa subunit; DNA fragmentation factor subunit alpha; ICA; ICAD; ICAD-L; ICAD-S; inhibitor of CAD
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,188,599 - 149,205,110 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4149,188,603 - 149,205,104 (+)EnsemblGRCm39 Ensembl
GRCm384149,104,142 - 149,120,653 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,104,146 - 149,120,647 (+)EnsemblGRCm38mm10GRCm38
MGSCv374148,478,262 - 148,494,759 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364147,947,953 - 147,964,450 (+)NCBIMGSCv36mm8
Celera4151,371,738 - 151,386,868 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-dexrazoxane  (EXP)
(1->4)-beta-D-glucan  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
[6]-Shogaol  (ISO)
aclacinomycin A  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
celecoxib  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
daunorubicin  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (EXP)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
dimethyl sulfoxide  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ellagic acid  (ISO)
embelin  (ISO)
enzyme inhibitor  (ISO)
equol  (ISO)
ethanol  (EXP)
fenamidone  (EXP)
folic acid  (EXP)
FR900359  (ISO)
furosemide  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
isoflurane  (ISO)
ivermectin  (ISO)
metformin  (ISO)
methyl methanesulfonate  (ISO)
Mitotane  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
nickel atom  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
oxybenzone  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
Parthenin  (ISO)
pentobarbital  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenylmercury acetate  (ISO)
piroxicam  (ISO)
pterostilbene  (EXP)
pyrethrins  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
titanium dioxide  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
nucleus  (ISO)
plasma membrane  (IEA,ISO)
protein-containing complex  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Characterization of the rat DNA fragmentation factor 35/Inhibitor of caspase-activated DNase (Short form). The endogenous inhibitor of caspase-dependent DNA fragmentation in neuronal apoptosis. Chen D, etal., J Biol Chem 2000 Dec 8;275(49):38508-17.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9422506   PMID:9422513   PMID:9564035   PMID:9770511   PMID:9867840   PMID:10349636   PMID:10601318   PMID:10834841   PMID:10837799   PMID:10903922   PMID:10932250   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:11478773   PMID:11785971   PMID:12044605   PMID:12144788   PMID:12477932   PMID:14557248   PMID:14610273   PMID:14663139   PMID:15572351   PMID:16141072  
PMID:16141073   PMID:16432220   PMID:17626049   PMID:18799693   PMID:21267068   PMID:21873635   PMID:22727028   PMID:23451280   PMID:32325033  


Genomics

Comparative Map Data
Dffa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394149,188,599 - 149,205,110 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4149,188,603 - 149,205,104 (+)EnsemblGRCm39 Ensembl
GRCm384149,104,142 - 149,120,653 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4149,104,146 - 149,120,647 (+)EnsemblGRCm38mm10GRCm38
MGSCv374148,478,262 - 148,494,759 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364147,947,953 - 147,964,450 (+)NCBIMGSCv36mm8
Celera4151,371,738 - 151,386,868 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.87NCBI
DFFA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38110,456,522 - 10,472,529 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl110,456,522 - 10,472,529 (-)EnsemblGRCh38hg38GRCh38
GRCh37110,516,579 - 10,532,586 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36110,443,175 - 10,455,200 (-)NCBINCBI36Build 36hg18NCBI36
Celera19,631,993 - 9,644,017 (-)NCBICelera
Cytogenetic Map1p36.22NCBI
HuRef19,674,182 - 9,686,174 (-)NCBIHuRef
CHM1_1110,508,330 - 10,520,370 (-)NCBICHM1_1
T2T-CHM13v2.0110,000,139 - 10,016,137 (-)NCBIT2T-CHM13v2.0
Dffa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85164,823,807 - 164,836,729 (+)NCBIGRCr8
mRatBN7.25159,540,715 - 159,553,639 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5159,540,715 - 159,553,633 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5162,257,408 - 162,270,330 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05164,078,196 - 164,091,121 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05164,034,568 - 164,047,493 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05165,922,893 - 165,935,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5165,922,915 - 165,935,821 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05169,573,089 - 169,586,003 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45166,179,130 - 166,192,029 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15166,189,332 - 166,200,048 (+)NCBI
Celera5157,811,683 - 157,824,582 (+)NCBICelera
Cytogenetic Map5q36NCBI
Dffa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554863,273,712 - 3,274,510 (+)NCBIChiLan1.0ChiLan1.0
DFFA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21217,754,203 - 217,768,613 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11216,400,486 - 216,414,533 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v019,221,096 - 9,232,813 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1110,445,553 - 10,457,547 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl110,445,553 - 10,457,547 (-)Ensemblpanpan1.1panPan2
DFFA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1285,364,819 - 85,372,473 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl285,364,851 - 85,373,772 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,966,306 - 81,973,968 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0286,099,825 - 86,107,488 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl286,099,863 - 86,109,086 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1282,847,197 - 82,854,858 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0283,849,698 - 83,857,360 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,912,608 - 84,920,270 (+)NCBIUU_Cfam_GSD_1.0
Dffa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505833,811,757 - 33,821,826 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366234,296,681 - 4,307,159 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366234,296,995 - 4,307,069 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DFFA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl670,724,590 - 70,736,236 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1670,725,403 - 70,736,264 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2664,658,250 - 64,669,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DFFA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120121,312,291 - 121,324,055 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20121,311,954 - 121,323,402 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605425,226,082 - 25,238,468 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dffa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248182,225,777 - 2,239,897 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:909
Count of miRNA genes:561
Interacting mature miRNAs:670
Transcripts:ENSMUST00000030816, ENSMUST00000103216, ENSMUST00000153781
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse

Markers in Region
D4Mit189  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384149,108,596 - 149,108,722UniSTSGRCm38
MGSCv374148,482,705 - 148,482,831UniSTSGRCm37
Cytogenetic Map4E2UniSTS
cM Map471.0UniSTS
Whitehead Genetic471.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_104263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA512775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB009375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB009376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI116789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI956986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL611967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB183843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI736905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU695917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY170336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY208552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY244454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY636093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU210839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000030816   ⟹   ENSMUSP00000030816
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4149,188,603 - 149,205,104 (+)Ensembl
GRCm38.p6 Ensembl4149,104,146 - 149,120,647 (+)Ensembl
Ensembl Acc Id: ENSMUST00000103216   ⟹   ENSMUSP00000099505
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4149,188,603 - 149,203,327 (+)Ensembl
GRCm38.p6 Ensembl4149,104,146 - 149,118,870 (+)Ensembl
Ensembl Acc Id: ENSMUST00000153781
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4149,192,226 - 149,192,691 (+)Ensembl
GRCm38.p6 Ensembl4149,107,769 - 149,108,234 (+)Ensembl
RefSeq Acc Id: NM_001025296   ⟹   NP_001020467
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394149,188,599 - 149,205,110 (+)NCBI
GRCm384149,104,142 - 149,120,653 (+)NCBI
MGSCv374148,478,262 - 148,494,759 (+)RGD
Celera4151,371,727 - 151,386,871 (+)NCBI
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010044   ⟹   NP_034174
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394149,188,599 - 149,202,585 (+)NCBI
GRCm384149,104,142 - 149,118,128 (+)NCBI
MGSCv374148,478,262 - 148,494,759 (+)RGD
Celera4151,371,727 - 151,386,871 (+)NCBI
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_104263
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394149,188,599 - 149,205,110 (+)NCBI
GRCm384149,104,142 - 149,120,653 (+)NCBI
Celera4151,371,727 - 151,386,871 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001020467   ⟸   NM_001025296
- Peptide Label: isoform a
- UniProtKB: O54787 (UniProtKB/Swiss-Prot),   B2KFX0 (UniProtKB/Swiss-Prot),   Q8BQC7 (UniProtKB/Swiss-Prot),   O54786 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_034174   ⟸   NM_010044
- Peptide Label: isoform b
- UniProtKB: Q8C535 (UniProtKB/TrEMBL),   Q8CA98 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000030816   ⟸   ENSMUST00000030816
Ensembl Acc Id: ENSMUSP00000099505   ⟸   ENSMUST00000103216
Protein Domains
CIDE-N

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54786-F1-model_v2 AlphaFold O54786 1-331 view protein structure

Promoters
RGD ID:6835137
Promoter ID:MM_KWN:40849
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4
Transcripts:ENSMUST00000105697,   OTTMUST00000025709,   OTTMUST00000025710
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364148,478,156 - 148,478,656 (+)MPROMDB
RGD ID:6885546
Promoter ID:EPDNEW_M6224
Type:initiation region
Name:Dffa_1
Description:Mus musculus DNA fragmentation factor, alpha subunit , transcriptvariant 3, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384149,104,151 - 149,104,211EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1196227 AgrOrtholog
Ensembl Genes ENSMUSG00000028974 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030816 ENTREZGENE
  ENSMUST00000030816.4 UniProtKB/Swiss-Prot
  ENSMUST00000103216 ENTREZGENE
  ENSMUST00000103216.10 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-terminal domain of DFF45/ICAD (DFF-C domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CIDE-N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DFF-C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DFF45 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_fragmentation_mid_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13347 UniProtKB/Swiss-Prot
MGD MGI:1196227 ENTREZGENE
NCBI Gene 13347 ENTREZGENE
PANTHER CELL DEATH ACTIVATOR CIDE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12306:SF16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CIDE-N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DFF-C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dffa PhenoGen
PIRSF DFF_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CIDE_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP CAD & PB1 domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81783 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2KFX0 ENTREZGENE
  DFFA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  O54787 ENTREZGENE
  Q8BQC7 ENTREZGENE
  Q8C535 ENTREZGENE, UniProtKB/TrEMBL
  Q8CA98 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2KFX0 UniProtKB/Swiss-Prot
  O54787 UniProtKB/Swiss-Prot
  Q8BQC7 UniProtKB/Swiss-Prot