Aurkaip1 (aurora kinase A interacting protein 1) - Rat Genome Database

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Gene: Aurkaip1 (aurora kinase A interacting protein 1) Mus musculus
Analyze
Symbol: Aurkaip1
Name: aurora kinase A interacting protein 1
RGD ID: 1615901
MGI Page MGI
Description: Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in positive regulation of proteolysis and protein ubiquitination. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human AURKAIP1 (aurora kinase A interacting protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 0610033H09Rik; 28S ribosomal protein S38, mitochondrial; Aip; Akip; AURKA-interacting protein; aurora kinase A-interacting protein; Aurora-A kinase interacting protein; MRP-S38; small ribosomal subunit protein mS38
RGD Orthologs
Human
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,915,709 - 155,917,555 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,915,729 - 155,917,587 (+)EnsemblGRCm39 Ensembl
GRCm384155,831,269 - 155,833,098 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,831,272 - 155,833,130 (+)EnsemblGRCm38mm10GRCm38
MGSCv374155,205,755 - 155,207,168 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,675,446 - 154,676,859 (+)NCBIMGSCv36mm8
Celera4158,102,482 - 158,103,895 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map487.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7671812   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11555487   PMID:12244051   PMID:12466851   PMID:12477932   PMID:14610273  
PMID:14681479   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17125467   PMID:18614015   PMID:18799693   PMID:21267068   PMID:21873635   PMID:25838379   PMID:27023846   PMID:33554859  
PMID:38355793  


Genomics

Comparative Map Data
Aurkaip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,915,709 - 155,917,555 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,915,729 - 155,917,587 (+)EnsemblGRCm39 Ensembl
GRCm384155,831,269 - 155,833,098 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,831,272 - 155,833,130 (+)EnsemblGRCm38mm10GRCm38
MGSCv374155,205,755 - 155,207,168 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,675,446 - 154,676,859 (+)NCBIMGSCv36mm8
Celera4158,102,482 - 158,103,895 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map487.55NCBI
AURKAIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,373,736 - 1,375,207 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,373,730 - 1,375,207 (-)EnsemblGRCh38hg38GRCh38
GRCh3711,309,116 - 1,310,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,298,973 - 1,300,443 (-)NCBINCBI36Build 36hg18NCBI36
Celera11,271,320 - 1,273,028 (+)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1581,461 - 583,169 (-)NCBIHuRef
CHM1_111,296,136 - 1,297,844 (-)NCBICHM1_1
T2T-CHM13v2.01804,285 - 805,756 (-)NCBIT2T-CHM13v2.0
Aurkaip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,437,958 - 9,438,857 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,437,511 - 9,438,945 (+)NCBIChiLan1.0ChiLan1.0
AURKAIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,850,541 - 226,852,331 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,548,052 - 225,549,858 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,234 - 130,866 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,329,414 - 1,331,225 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,329,414 - 1,331,203 (-)Ensemblpanpan1.1panPan2
AURKAIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,539,987 - 56,541,578 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,539,991 - 56,541,388 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,616,167 - 56,617,768 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,742,074 - 56,743,675 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,742,078 - 56,743,475 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,732,793 - 56,734,394 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,625,059 - 56,626,660 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0557,015,342 - 57,016,943 (-)NCBIUU_Cfam_GSD_1.0
Aurkaip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,687,717 - 27,689,414 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367371,776,480 - 1,779,611 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367371,776,550 - 1,778,233 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AURKAIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,656,119 - 63,657,472 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,656,120 - 63,657,568 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AURKAIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,074,660 - 130,076,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20130,075,295 - 130,076,765 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605434,631,140 - 34,632,908 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aurkaip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248188,246,646 - 8,248,005 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248188,246,636 - 8,248,002 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aurkaip1
141 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:949
Count of miRNA genes:416
Interacting mature miRNAs:495
Transcripts:ENSMUST00000084097, ENSMUST00000105591, ENSMUST00000105592, ENSMUST00000129711, ENSMUST00000139651, ENSMUST00000151222
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138943725156860686Mouse

Markers in Region
UniSTS:235120  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384155,832,899 - 155,833,010UniSTSGRCm38
MGSCv374155,207,008 - 155,207,119UniSTSGRCm37
Celera4158,103,734 - 158,103,845UniSTS
Cytogenetic Map4E2UniSTS
cM Map483.0UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000084097   ⟹   ENSMUSP00000081114
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4155,915,808 - 155,917,587 (+)Ensembl
GRCm38.p6 Ensembl4155,831,351 - 155,833,130 (+)Ensembl
Ensembl Acc Id: ENSMUST00000105591   ⟹   ENSMUSP00000101216
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4155,916,126 - 155,917,488 (+)Ensembl
GRCm38.p6 Ensembl4155,831,669 - 155,833,031 (+)Ensembl
Ensembl Acc Id: ENSMUST00000105592   ⟹   ENSMUSP00000101217
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4155,916,116 - 155,917,518 (+)Ensembl
GRCm38.p6 Ensembl4155,831,659 - 155,833,061 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4155,916,122 - 155,916,986 (+)Ensembl
GRCm38.p6 Ensembl4155,831,665 - 155,832,529 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139651   ⟹   ENSMUSP00000117870
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4155,915,729 - 155,917,196 (+)Ensembl
GRCm38.p6 Ensembl4155,831,272 - 155,832,739 (+)Ensembl
Ensembl Acc Id: ENSMUST00000151222
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4155,916,076 - 155,916,922 (+)Ensembl
GRCm38.p6 Ensembl4155,831,619 - 155,832,465 (+)Ensembl
RefSeq Acc Id: NM_025338   ⟹   NP_079614
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,915,726 - 155,917,555 (+)NCBI
GRCm384155,831,269 - 155,833,098 (+)ENTREZGENE
MGSCv374155,205,755 - 155,207,168 (+)RGD
Celera4158,102,111 - 158,103,934 (+)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539095   ⟹   XP_006539158
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,915,709 - 155,917,526 (+)NCBI
GRCm384155,831,305 - 155,833,069 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036164304   ⟹   XP_036020197
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394155,915,762 - 155,917,526 (+)NCBI
Sequence:
RefSeq Acc Id: NP_079614   ⟸   NM_025338
- UniProtKB: Q9DCJ7 (UniProtKB/Swiss-Prot),   Q9D1J7 (UniProtKB/Swiss-Prot),   Q3TZ21 (UniProtKB/TrEMBL),   Q8CCC0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006539158   ⟸   XM_006539095
- Peptide Label: isoform X1
- UniProtKB: Q9DCJ7 (UniProtKB/Swiss-Prot),   Q9D1J7 (UniProtKB/Swiss-Prot),   Q3TZ21 (UniProtKB/TrEMBL),   Q8CCC0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000117870   ⟸   ENSMUST00000139651
Ensembl Acc Id: ENSMUSP00000101216   ⟸   ENSMUST00000105591
Ensembl Acc Id: ENSMUSP00000101217   ⟸   ENSMUST00000105592
Ensembl Acc Id: ENSMUSP00000081114   ⟸   ENSMUST00000084097
RefSeq Acc Id: XP_036020197   ⟸   XM_036164304
- Peptide Label: isoform X1
- UniProtKB: Q9DCJ7 (UniProtKB/Swiss-Prot),   Q9D1J7 (UniProtKB/Swiss-Prot),   Q3TZ21 (UniProtKB/TrEMBL),   Q8CCC0 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DCJ7-F1-model_v2 AlphaFold Q9DCJ7 1-200 view protein structure

Promoters
RGD ID:6834924
Promoter ID:MM_KWN:41189
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000105591,   ENSMUST00000105592,   OTTMUST00000025540,   OTTMUST00000025542,   OTTMUST00000025543,   OTTMUST00000025544
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364155,204,606 - 155,205,872 (+)MPROMDB
RGD ID:6885822
Promoter ID:EPDNEW_M6362
Type:multiple initiation site
Name:Aurkaip1_1
Description:Mus musculus aurora kinase A interacting protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6363  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384155,831,334 - 155,831,394EPDNEW
RGD ID:6885824
Promoter ID:EPDNEW_M6363
Type:initiation region
Name:Aurkaip1_2
Description:Mus musculus aurora kinase A interacting protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6362  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384155,831,658 - 155,831,718EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913327 AgrOrtholog
Ensembl Genes ENSMUSG00000065990 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000084097 ENTREZGENE
  ENSMUST00000084097.12 UniProtKB/Swiss-Prot
  ENSMUST00000105591 ENTREZGENE
  ENSMUST00000105591.2 UniProtKB/Swiss-Prot
  ENSMUST00000105592 ENTREZGENE
  ENSMUST00000105592.8 UniProtKB/Swiss-Prot
  ENSMUST00000139651.8 UniProtKB/TrEMBL
InterPro DUF1713 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66077 UniProtKB/Swiss-Prot
MGD MGI:1913327 ENTREZGENE
NCBI Gene 66077 ENTREZGENE
PANTHER AURORA KINASE A-INTERACTING PROTEIN UniProtKB/Swiss-Prot
  AURORA KINASE A-INTERACTING PROTEIN UniProtKB/Swiss-Prot
  AURORA KINASE A-INTERACTING PROTEIN UniProtKB/TrEMBL
  AURORA KINASE A-INTERACTING PROTEIN UniProtKB/TrEMBL
Pfam DUF1713 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aurkaip1 PhenoGen
SMART DUF1713 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MQH8_MOUSE UniProtKB/TrEMBL
  AKIP_MOUSE UniProtKB/Swiss-Prot
  Q3TZ21 ENTREZGENE, UniProtKB/TrEMBL
  Q8CCC0 ENTREZGENE, UniProtKB/TrEMBL
  Q91X73_MOUSE UniProtKB/TrEMBL
  Q9D1J7 ENTREZGENE
  Q9DCJ7 ENTREZGENE
UniProt Secondary Q9D1J7 UniProtKB/Swiss-Prot