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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diagnostic agent
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Accession:CHEBI:33295 term browser browse the term
Definition:A substance administered to aid diagnosis of a disease.
Synonyms:related_synonym: diagnostic aid


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2',7'-bis-(2-carboxyethyl)carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO Mefloquine inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] CTD PMID:16004972 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases export
multiple interactions
ISO ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein
daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; hesperetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; naringenin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Quercetin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; resveratrol inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Silymarin inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; verlukast inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]
CTD PMID:16156793 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
5(6)-carboxy-2',7'-dichlorofluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
multiple interactions
increases export
increases transport
EXP
ISO
ABCC2 protein affects the transport of 5(6)-carboxy-2',7'-dichlorofluorescein
4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; cyanoginosin LR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Cyclosporine inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin RR inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; microcystin-LF inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Tobacco Smoke Pollution inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]
ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog
[ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein; ABCC2 gene mutant form inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]; ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein; Atorvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Fluvastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Pravastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:19326901 PMID:21240898 PMID:21341280 PMID:23562342 PMID:24907646 PMID:24909372 PMID:24973091 PMID:25862123 PMID:27450509 PMID:31348918 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases transport
EXP
ISO
[ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein
Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:24907646 PMID:31348918 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions
increases transport
ISO Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
5-carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases transport
ISO quercetin 3'-sulfate inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]; quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein] CTD PMID:21244849 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
5-chloromethylfluorescein diacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO ABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione] CTD PMID:16049127 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
6-carboxyfluorescein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases export ISO ABCC1 protein results in increased export of 6-carboxyfluorescein CTD PMID:17940500 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
multiple interactions
ISO ABCC2 protein affects the export of 6-carboxyfluorescein
Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]
CTD PMID:11477083 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
increases import
ISO 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein] CTD PMID:28629854 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases import
multiple interactions
ISO SLC22A8 protein results in increased import of 6-carboxyfluorescein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine promotes the reaction [2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 2-amino-9H-pyrido(2,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; 2-amino-9H-pyrido(2,3-b)indole promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]]; 3-amino-1-methyl-5H-pyrido(4,3-b)indole inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Cadmium Chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; glutaric acid promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; lead chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; sodium arsenate promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]
CTD PMID:28629854 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
amidotrizoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions
increases expression
EXP telmisartan inhibits the reaction [Diatrizoate results in increased expression of AGT protein] CTD PMID:19452295 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO Plant Extracts inhibits the reaction [Diatrizoate results in decreased phosphorylation of AKT1 protein] CTD PMID:25603236 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Diatrizoate co-treated with Iodine] results in increased expression of BAX protein CTD PMID:17173243 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Diatrizoate co-treated with Iodine] results in increased expression of BCL2 protein CTD PMID:17173243 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 affects expression
multiple interactions
increases activity
ISO
EXP
Diatrizoate affects the expression of CASP3 protein
[Diatrizoate co-treated with Iodine] results in increased activity of CASP3 protein
telmisartan inhibits the reaction [Diatrizoate results in increased activity of CASP3 protein]
CTD PMID:17173243 PMID:19452295 PMID:21036957 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G F2 coagulation factor II multiple interactions ISO Diatrizoate inhibits the reaction [F2 protein binds to SERPINC1 protein] CTD PMID:2020943 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Foxo1 forkhead box O1 decreases phosphorylation
multiple interactions
ISO Diatrizoate results in decreased phosphorylation of FOXO1 protein
Plant Extracts inhibits the reaction [Diatrizoate results in decreased phosphorylation of FOXO1 protein]
CTD PMID:25603236 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 affects phosphorylation ISO Diatrizoate affects the phosphorylation of FOXO3 protein CTD PMID:21036957 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation
multiple interactions
ISO Diatrizoate affects the phosphorylation of MAPK1 protein
Plant Extracts affects the reaction [Diatrizoate affects the phosphorylation of MAPK1 protein]
CTD PMID:25603236 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
affects phosphorylation
ISO Plant Extracts affects the reaction [Diatrizoate affects the phosphorylation of MAPK3 protein] CTD PMID:25603236 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Diatrizoate results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO Diatrizoate results in increased phosphorylation of MAPK9 protein CTD PMID:21036957 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase decreases expression
multiple interactions
ISO Diatrizoate results in decreased expression of PIM1 protein
Plant Extracts inhibits the reaction [Diatrizoate results in decreased expression of PIM1 protein]
CTD PMID:25603236 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation ISO Diatrizoate results in increased phosphorylation of RELA protein CTD PMID:21036957 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Serpinc1 serpin family C member 1 multiple interactions ISO Diatrizoate inhibits the reaction [F2 protein binds to SERPINC1 protein] CTD PMID:2020943 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects expression ISO Diatrizoate affects the expression of STAT3 protein modified form CTD PMID:21036957 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
barium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases expression EXP Barium Sulfate results in increased expression of ALB mRNA CTD PMID:29463257 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Barium Sulfate results in increased expression of BIRC5 mRNA CTD PMID:29463257 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression EXP Barium Sulfate results in increased expression of CCL11 mRNA CTD PMID:29463257 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion
increases expression
EXP Barium Sulfate results in increased secretion of CCL2 protein
Barium Sulfate results in increased expression of CCL2 mRNA
CTD PMID:29463257 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 affects expression EXP Barium Sulfate affects the expression of CCL20 mRNA CTD PMID:29463257 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression EXP Barium Sulfate results in increased expression of CCL22 mRNA CTD PMID:29463257 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 increases expression EXP Barium Sulfate results in increased expression of CCL24 mRNA CTD PMID:29463257 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression EXP Barium Sulfate results in decreased expression of CCL4 mRNA CTD PMID:29463257 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP Barium Sulfate results in increased expression of CCL7 mRNA CTD PMID:29463257 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression EXP Barium Sulfate results in increased expression of CCR2 mRNA CTD PMID:29463257
G Cd40lg CD40 ligand decreases expression EXP Barium Sulfate results in decreased expression of CD40LG mRNA CTD PMID:29463257 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression EXP Barium Sulfate results in increased expression of CXCL9 mRNA CTD PMID:29463257 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression EXP Barium Sulfate results in increased expression of CXCR3 mRNA CTD PMID:29463257 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Barium Sulfate results in increased expression of CYP4A1 mRNA CTD PMID:11124224 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP Barium Sulfate results in increased expression of CYP4A2 mRNA CTD PMID:11124224 NCBI chr 5:134,196,910...134,207,888
Ensembl chr 5:134,196,912...134,207,863
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Barium Sulfate results in increased expression of CYP4A3 mRNA CTD PMID:11124224 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 increases expression EXP Barium Sulfate results in increased expression of CYP4F1 mRNA CTD PMID:14644421 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression EXP Barium Sulfate results in increased expression of CYP4F4 mRNA CTD PMID:14644421 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 increases expression EXP Barium Sulfate results in increased expression of CYP4F6 mRNA CTD PMID:14644421 NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410
JBrowse link
G Exo1 exonuclease 1 affects expression EXP Barium Sulfate affects the expression of EXO1 mRNA CTD PMID:29463257 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression EXP Barium Sulfate results in decreased expression of FABP4 mRNA CTD PMID:29463257 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP Barium Sulfate results in decreased expression of HBA1 mRNA CTD PMID:29463257 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Il2rb interleukin 2 receptor subunit beta decreases expression EXP Barium Sulfate results in decreased expression of IL2RB mRNA CTD PMID:29463257 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
JBrowse link
G Il6 interleukin 6 increases expression ISO Barium Sulfate results in increased expression of IL6 protein CTD PMID:11403239 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Krt1 keratin 1 increases expression EXP Barium Sulfate results in increased expression of KRT1 mRNA CTD PMID:29463257 NCBI chr 7:143,448,318...143,453,544
Ensembl chr 7:143,448,318...143,453,544
JBrowse link
G Lig4 DNA ligase 4 increases expression EXP Barium Sulfate results in increased expression of LIG4 mRNA CTD PMID:29463257 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Lpo lactoperoxidase increases expression EXP Barium Sulfate results in increased expression of LPO mRNA; Barium Sulfate results in increased expression of LPO protein CTD PMID:29463257 NCBI chr10:75,100,385...75,120,247
Ensembl chr10:75,100,385...75,120,247
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP Barium Sulfate results in increased expression of MMP12 mRNA; Barium Sulfate results in increased expression of MMP12 protein CTD PMID:29463257 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mutyh mutY DNA glycosylase increases expression EXP Barium Sulfate results in increased expression of MUTYH mRNA CTD PMID:29463257 NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
JBrowse link
G Ngb neuroglobin decreases expression EXP Barium Sulfate results in decreased expression of NGB mRNA CTD PMID:29463257 NCBI chr 6:111,126,259...111,131,699
Ensembl chr 6:111,126,261...111,132,320
JBrowse link
G Noxo1 NADPH oxidase organizer 1 increases expression EXP Barium Sulfate results in increased expression of NOXO1 mRNA CTD PMID:29463257 NCBI chr10:14,062,331...14,066,918
Ensembl chr10:14,062,331...14,066,918
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression EXP Barium Sulfate results in increased expression of OPCML mRNA CTD PMID:29463257 NCBI chr 8:28,842,202...29,967,300
Ensembl chr 8:29,453,643...29,962,825
JBrowse link
G Pf4 platelet factor 4 increases expression EXP Barium Sulfate results in increased expression of PF4 mRNA CTD PMID:29463257 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Scd stearoyl-CoA desaturase affects expression EXP Barium Sulfate affects the expression of SCD1 mRNA CTD PMID:29463257 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Tcf21 transcription factor 21 decreases expression EXP Barium Sulfate results in decreased expression of TCF21 mRNA CTD PMID:29463257 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Thbs2 thrombospondin 2 increases expression EXP Barium Sulfate results in increased expression of THBS2 mRNA CTD PMID:29463257 NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP Barium Sulfate results in increased expression of TOP2A mRNA CTD PMID:29463257 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Txnip thioredoxin interacting protein decreases expression EXP Barium Sulfate results in decreased expression of TXNIP mRNA CTD PMID:29463257 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 increases expression EXP Barium Sulfate results in increased expression of XRCC2 mRNA CTD PMID:29463257 NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
JBrowse link
ceruletide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
ISO PTHLH protein promotes the reaction [Ceruletide results in increased expression of ACTA2 protein] CTD PMID:25035110 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression EXP Ceruletide results in decreased expression of AHCY protein CTD PMID:18024178 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression EXP Ceruletide results in increased expression of AKR1B1 protein CTD PMID:18024178 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein CTD PMID:26390243 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin decreases expression EXP Ceruletide results in decreased expression of ALB protein modified form CTD PMID:17169977 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression ISO Ceruletide results in increased expression of BDKRB1 mRNA CTD PMID:21484880 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression ISO Ceruletide results in increased expression of BDKRB2 mRNA CTD PMID:21484880 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Brd4 bromodomain containing 4 multiple interactions ISO (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein CTD PMID:26390243 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Glycodeoxycholic Acid co-treated with Ceruletide] results in decreased activity of CASP3 protein; Ceruletide results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:16339139 PMID:18832452 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions EXP Ceruletide results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:16339139 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Ceruletide results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:16339139 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO PPARG affects the reaction [Ceruletide results in increased expression of CCL2 mRNA]; rosiglitazone inhibits the reaction [Ceruletide results in increased expression of CCL2 mRNA] CTD PMID:17463185 PMID:21484880 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 increases expression EXP Ceruletide results in increased expression of CCT2 protein CTD PMID:18024178 NCBI chr 7:60,106,532...60,122,779
Ensembl chr 7:60,109,974...60,122,805
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression
multiple interactions
EXP Ceruletide results in increased expression of CEBPA mRNA
[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPA protein; Dietary Fats promotes the reaction [Ceruletide results in increased expression of CEBPA mRNA]; Quercetin inhibits the reaction [[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPA protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of CEBPA mRNA]
CTD PMID:26873426 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression
EXP [Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPB protein; Dietary Fats promotes the reaction [Ceruletide results in increased expression of CEBPB mRNA]; Quercetin inhibits the reaction [[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPB protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of CEBPB mRNA] CTD PMID:26873426 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
ISO
EXP
PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]
PTHLH protein inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]
CTD PMID:22280800 PMID:25035110 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Ctsb cathepsin B affects localization
multiple interactions
EXP Ceruletide affects the localization of CTSB protein
sodium arsenite inhibits the reaction [Ceruletide affects the localization of CTSB protein]
CTD PMID:17941083 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Ceruletide results in increased expression of CXCL1 mRNA
AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; AM 251 promotes the reaction [iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; HU 211 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; iodopravadoline inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]; iodopravadoline promotes the reaction [AM 251 inhibits the reaction [Ceruletide results in increased expression of CXCL1 mRNA]]; PPARG affects the reaction [Ceruletide results in increased expression of CXCL1 mRNA]
CTD PMID:17463185 PMID:17484889 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions
EXP Ceruletide results in increased expression of ERN1 mRNA; Ceruletide results in increased expression of ERN1 protein
Dietary Fats promotes the reaction [Ceruletide results in increased expression of ERN1 mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased expression of ERN1 protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of ERN1 mRNA]; Quercetin inhibits the reaction [Ceruletide results in increased expression of ERN1 protein]
CTD PMID:26873426 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression EXP Ceruletide results in increased expression of GLUD1 protein CTD PMID:18024178 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
ISO isoborneol inhibits the reaction [Ceruletide results in increased expression of GPT protein] CTD PMID:33166053 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 increases expression EXP Ceruletide results in increased expression of HNRNPH1 protein CTD PMID:18024178 NCBI chr10:35,872,619...35,879,911
Ensembl chr10:35,870,232...35,879,910
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression EXP Ceruletide results in decreased expression of HSPA5 protein CTD PMID:18024178 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression EXP Ceruletide results in decreased expression of HSPA8 protein CTD PMID:18024178 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression EXP Ceruletide results in increased expression of HYOU1 protein CTD PMID:18024178 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of ICAM1 mRNA]
rosiglitazone inhibits the reaction [Ceruletide results in increased expression of ICAM1 mRNA]
CTD PMID:17463185 PMID:25035110 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il10 interleukin 10 multiple interactions EXP [resveratrol co-treated with Ceruletide] results in increased expression of IL10 protein CTD PMID:24234420 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
increases secretion
EXP
ISO
Ceruletide results in increased expression of IL1B mRNA; Ceruletide results in increased expression of IL1B protein
isoborneol inhibits the reaction [Ceruletide results in increased expression of IL1B protein]
Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL1B mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased secretion of IL1B protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL1B mRNA]]; resveratrol inhibits the reaction [Ceruletide results in increased expression of IL1B protein]
CTD PMID:14751415 PMID:21484880 PMID:24234420 PMID:26873426 PMID:33166053 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
increases secretion
ISO
EXP
Ceruletide results in increased expression of IL6 mRNA
Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased secretion of IL6 protein]; PTHLH protein inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Dietary Fats promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]]
(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein; HU 211 inhibits the reaction [Ceruletide results in increased expression of IL6 protein]; IL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]]; isoborneol inhibits the reaction [Ceruletide results in increased expression of IL6 protein]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
Ceruletide results in increased expression of IL6 mRNA; Ceruletide results in increased expression of IL6 protein
PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
CTD PMID:17484889 PMID:22280800 PMID:25035110 PMID:26390243 PMID:26873426 PMID:33166053 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Ceruletide results in increased expression of JUN mRNA
rosiglitazone inhibits the reaction [Ceruletide results in increased expression of JUN mRNA]
CTD PMID:17463185 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein]; (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein]; (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein]; (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein; [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of IL6 protein; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein; IL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]] CTD PMID:26390243 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Mir216a microRNA 216a increases expression EXP Ceruletide results in increased expression of MIR216A mRNA CTD PMID:27521901 NCBI chr14:113,112,129...113,112,234
Ensembl chr14:113,112,129...113,112,234
JBrowse link
G Mir216b microRNA 216b increases expression EXP Ceruletide results in increased expression of MIR216B mRNA CTD PMID:27521901 NCBI chr14:113,101,078...113,101,179
Ensembl chr14:113,101,078...113,101,179
JBrowse link
G Mir217 microRNA 217 increases expression EXP Ceruletide results in increased expression of MIR217 mRNA CTD PMID:27521901 NCBI chr14:113,119,529...113,119,633
Ensembl chr14:113,119,529...113,119,633
JBrowse link
G Mpo myeloperoxidase increases expression
increases activity
multiple interactions
ISO Ceruletide results in increased expression of MPO protein
Ceruletide results in increased activity of MPO protein
HU 211 inhibits the reaction [Ceruletide results in increased expression of MPO protein]; isoborneol inhibits the reaction [Ceruletide results in increased activity of MPO protein]
CTD PMID:17484889 PMID:33166053 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
decreases expression
ISO isoborneol inhibits the reaction [Ceruletide results in decreased expression of NFE2L2 protein] CTD PMID:33166053 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation
multiple interactions
EXP Ceruletide results in increased degradation of NFKBIA protein
sodium arsenite inhibits the reaction [Ceruletide results in increased degradation of NFKBIA protein]
CTD PMID:17941083 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO Ceruletide results in increased expression of NOS2 protein
isoborneol inhibits the reaction [Ceruletide results in increased expression of NOS2 protein]
CTD PMID:33166053 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP Ceruletide results in increased expression of PDIA4 protein CTD PMID:18024178 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO PPARG affects the reaction [Ceruletide results in increased expression of CCL2 mRNA]; PPARG affects the reaction [Ceruletide results in increased expression of CXCL1 mRNA] CTD PMID:17463185 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression EXP Ceruletide results in increased expression of PRDX2 protein CTD PMID:18024178 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Ceruletide results in increased expression of PTGS2 mRNA; Ceruletide results in increased expression of PTGS2 protein CTD PMID:14751415 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pthlh parathyroid hormone-like hormone multiple interactions
affects response to substance
increases expression
ISO
EXP
PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of ICAM1 mRNA]; PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
Ethanol results in increased susceptibility to [Ceruletide results in increased expression of PTHLH mRNA]; PTHLH protein inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein inhibits the reaction [Ceruletide results in increased expression of IL6 mRNA]
PTHLH protein affects the susceptibility to Ceruletide
Ceruletide results in increased expression of PTHLH mRNA; Ceruletide results in increased expression of PTHLH protein
PTHLH protein promotes the reaction [Ceruletide results in increased expression of ACTA2 protein]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]; PTHLH protein promotes the reaction [Ceruletide results in increased expression of IL6 mRNA]
CTD PMID:22280800 PMID:25035110 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases phosphorylation
increases expression
ISO ent-1,3,6,11-tetrahydroxykaur-16-ene-15-one 3,11-diacetate inhibits the reaction [Ceruletide results in increased expression of RELA protein]; isoborneol inhibits the reaction [Ceruletide results in decreased phosphorylation of RELA protein] CTD PMID:22982818 PMID:33166053 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases cleavage EXP Ceruletide results in increased cleavage of RIPK1 protein CTD PMID:16339139 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 increases expression EXP Ceruletide results in increased expression of RUVBL1 protein CTD PMID:18024178 NCBI chr 4:120,411,917...120,447,458
Ensembl chr 4:120,411,991...120,447,455
JBrowse link
G Serpinf1 serpin family F member 1 increases activity EXP cerulein increases activity of Serpinf1 protein in blood RGD PMID:10423332 RGD:1625538 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression
ISO isoborneol inhibits the reaction [Ceruletide results in decreased expression of SOD1 protein] CTD PMID:33166053 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]; [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein; IL6 protein inhibits the reaction [(+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of STAT3 protein]] CTD PMID:26390243 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
increases secretion
EXP
ISO
Ceruletide results in increased expression of TNF mRNA; Ceruletide results in increased expression of TNF protein
isoborneol inhibits the reaction [Ceruletide results in increased expression of TNF protein]
2-acetoxy-5-(2-4-(trifluoromethyl)phenethylamino)benzoic acid inhibits the reaction [[Ceruletide co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; [Ceruletide co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; arsenic trioxide inhibits the reaction [Ceruletide results in increased expression of TNF mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased expression of TNF mRNA]; Dietary Fats promotes the reaction [Ceruletide results in increased secretion of TNF protein]; Pentoxifylline inhibits the reaction [Ceruletide results in increased expression of TNF protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Dietary Fats promotes the reaction [Ceruletide results in increased expression of TNF mRNA]]
CTD PMID:10773043 PMID:17517186 PMID:22575522 PMID:26873426 PMID:33166053 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Ceruletide results in increased expression of TPI1 protein CTD PMID:18024178 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
Ensembl chr 9:157,328,379...157,331,905
JBrowse link
G Vcp valosin-containing protein decreases expression EXP Ceruletide results in decreased expression of VCP protein CTD PMID:18024178 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Xbp1 X-box binding protein 1 increases expression
multiple interactions
EXP Ceruletide results in increased expression of XBP1 mRNA alternative form; Ceruletide results in increased expression of XBP1 protein alternative form
Dietary Fats promotes the reaction [Ceruletide results in increased expression of XBP1 mRNA alternative form]; Dietary Fats promotes the reaction [Ceruletide results in increased expression of XBP1 protein alternative form]; Quercetin inhibits the reaction [Ceruletide results in increased expression of XBP1 mRNA alternative form]; Quercetin inhibits the reaction [Ceruletide results in increased expression of XBP1 protein alternative form]
CTD PMID:26873426 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases degradation EXP Ceruletide results in increased degradation of XIAP protein CTD PMID:16339139 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
corticotropin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase increases activity ISO Adrenocorticotropic Hormone results in increased activity of ADA protein CTD PMID:8868375 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Calca calcitonin-related polypeptide alpha increases abundance EXP CALCA protein results in increased abundance of Adrenocorticotropic Hormone CTD PMID:12639925 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases activity EXP Adrenocorticotropic Hormone results in decreased activity of CNP protein CTD PMID:3030154 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases secretion
EXP Astemizole inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]; E 4031 inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]]; Tetraethylammonium promotes the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone] CTD PMID:18835572 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects abundance ISO CYP17A1 protein affects the abundance of Adrenocorticotropic Hormone CTD PMID:18645707 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO Adrenocorticotropic Hormone inhibits the reaction [INS protein results in increased secretion of GH1 protein] CTD PMID:3008584 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
affects expression
EXP Bupropion inhibits the reaction [Adrenocorticotropic Hormone affects the expression of HTR2A mRNA] CTD PMID:18239281 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Adrenocorticotropic Hormone inhibits the reaction [INS protein results in increased secretion of GH1 protein] CTD PMID:3008584 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects abundance ISO NR3C1 gene polymorphism affects the abundance of Adrenocorticotropic Hormone CTD PMID:17716631 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions ISO Cocaine promotes the reaction [PPP1R1B protein results in increased abundance of Adrenocorticotropic Hormone] CTD PMID:10516482 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ucn2 urocortin 2 increases abundance ISO UCN2 protein results in increased abundance of Adrenocorticotropic Hormone CTD PMID:16330704 NCBI chr 8:117,727,216...117,728,765
Ensembl chr 8:117,727,877...117,728,764
JBrowse link
cosyntropin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression ISO Cosyntropin results in decreased expression of HSD11B2 protein CTD PMID:11082157 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
creatinine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arntl aryl hydrocarbon receptor nuclear translocator-like increases abundance ISO ARNTL gene mutant form results in increased abundance of Creatinine CTD PMID:27056296 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine] CTD PMID:24709313 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Creatinine] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Lepr leptin receptor affects abundance
multiple interactions
increases abundance
ISO LEPR affects the abundance of Creatinine
Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine]
CTD PMID:20567778 PMID:29988851 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO [NFE2L2 protein affects the susceptibility to ochratoxin A] which results in increased abundance of Creatinine CTD PMID:28710020 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [SC 560 results in decreased activity of PTGS1 protein] which results in increased abundance of Creatinine CTD PMID:19629487 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Creatinine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Creatinine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
JBrowse link
G Sod2 superoxide dismutase 2 decreases abundance ISO SOD2 protein results in decreased abundance of Creatinine CTD PMID:19917352 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
desmopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 increases expression
multiple interactions
ISO
EXP
Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA; Deamino Arginine Vasopressin results in increased expression of AQP2 protein
Deamino Arginine Vasopressin inhibits the reaction [aluminum lactate results in decreased expression of AQP2 protein]; Deamino Arginine Vasopressin results in increased expression of and results in increased uptake of and results in increased ubiquitination of AQP2 protein
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]
CTD PMID:16495377 PMID:16675087 PMID:21734099 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Avpr2 arginine vasopressin receptor 2 multiple interactions EXP
ISO
[Deamino Arginine Vasopressin binds to and results in increased activity of AVPR2 protein] which results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid CTD PMID:1399968 PMID:15685210 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO Deamino Arginine Vasopressin results in increased activity of CFTR protein CTD PMID:15685210 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cul5 cullin 5 increases expression EXP Deamino Arginine Vasopressin results in increased expression of CUL5 protein CTD PMID:21734099 NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation
multiple interactions
EXP Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]
CTD PMID:15347643 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression EXP Deamino Arginine Vasopressin results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1B mRNA CTD PMID:11711512 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1G mRNA CTD PMID:11711512 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268
JBrowse link
G Vwf von Willebrand factor increases activity
increases secretion
ISO Deamino Arginine Vasopressin results in increased activity of VWF protein
Deamino Arginine Vasopressin results in increased secretion of VWF protein
CTD PMID:1837767 PMID:2738447 PMID:3259400 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
dimethyl sulfoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Dimethyl Sulfoxide results in increased expression of A2M mRNA CTD PMID:12883083 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression ISO Dimethyl Sulfoxide affects the expression of ABCB1 mRNA CTD PMID:12843640 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:11682029 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of ACTC1 mRNA
Dimethyl Sulfoxide results in decreased expression of ACTC1 mRNA
CTD PMID:22105179 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Agrp agouti related neuropeptide affects expression ISO Dimethyl Sulfoxide affects the expression of AGRP mRNA CTD PMID:24834073 NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases expression
ISO Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]
Dimethyl Sulfoxide results in decreased expression of AHR mRNA
CTD PMID:16675542 PMID:22486318 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aicda activation-induced cytidine deaminase affects expression ISO Dimethyl Sulfoxide affects the expression of AICDA mRNA CTD PMID:24834073 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
affects localization
ISO Dimethyl Sulfoxide inhibits the reaction [Acetaminophen affects the localization of AIFM1 protein]
Dimethyl Sulfoxide affects the localization of AIFM1 protein
CTD PMID:20423716 PMID:22535522 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of ALAS2 mRNA CTD PMID:21296123 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Alb albumin decreases expression ISO
EXP
Dimethyl Sulfoxide results in decreased expression of ALB mRNA
Dimethyl Sulfoxide results in decreased expression of ALB mRNA; Dimethyl Sulfoxide results in decreased expression of ALB protein
CTD PMID:14757319 PMID:22105179 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Dimethyl Sulfoxide results in increased expression of ALDH1A1 mRNA CTD PMID:22193206 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein] CTD PMID:23751068 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Apoa1 apolipoprotein A1 increases expression
increases activity
ISO
EXP
Dimethyl Sulfoxide results in increased expression of APOA1 mRNA; Dimethyl Sulfoxide results in increased expression of APOA1 protein
Dimethyl Sulfoxide results in increased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apom apolipoprotein M affects expression ISO Dimethyl Sulfoxide affects the expression of APOM mRNA CTD PMID:24834073 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G Aqp1 aquaporin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of AQP1 mRNA CTD PMID:22193206 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Ar androgen receptor multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Androgens results in increased activity of AR protein] CTD PMID:28377212 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 affects expression ISO Dimethyl Sulfoxide affects the expression of ARPC4 mRNA CTD PMID:24834073 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATF3 mRNA CTD PMID:22193206 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATP1A2 mRNA CTD PMID:22193206 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATP1B1 mRNA CTD PMID:22193206 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATP1B3 mRNA CTD PMID:22193206 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atp5mf ATP synthase membrane subunit f affects expression ISO Dimethyl Sulfoxide affects the expression of ATP5MF mRNA CTD PMID:24834073 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of AURKAIP1 mRNA CTD PMID:24834073 NCBI chr 5:173,274,433...173,276,170
Ensembl chr 5:173,256,637...173,276,169
JBrowse link
G Barhl2 BarH-like homeobox 2 affects expression ISO Dimethyl Sulfoxide affects the expression of BARHL2 mRNA CTD PMID:24834073 NCBI chr14:4,362,717...4,367,614
Ensembl chr14:4,362,717...4,367,605
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of BAX mRNA
Quercetin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of BAX mRNA]
CTD PMID:17652743 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bend6 BEN domain containing 6 affects expression ISO Dimethyl Sulfoxide affects the expression of BEND6 mRNA CTD PMID:24834073 NCBI chr 9:38,297,253...38,351,312
Ensembl chr 9:38,297,322...38,351,024
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of BTG2 mRNA CTD PMID:22193206 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of CADM1 mRNA CTD PMID:22193206 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
EXP
ISO
Dimethyl Sulfoxide results in decreased cleavage of and results in decreased activity of CASP3 protein
Dimethyl Sulfoxide results in increased cleavage of CASP3 protein
CTD PMID:12370186 PMID:22535522 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA] CTD PMID:9169468 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases secretion
decreases expression
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Dimethyl Sulfoxide results in increased secretion of CCL2 protein]
Dimethyl Sulfoxide results in decreased expression of CCL2 mRNA
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of CCL2 mRNA]
CTD PMID:10925121 PMID:14576080 PMID:15689417 PMID:17529908 PMID:21878375 PMID:26860701 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 affects expression ISO Dimethyl Sulfoxide affects the expression of CCL28 mRNA CTD PMID:24834073 NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein] CTD PMID:21878375 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd14 CD14 molecule increases expression ISO Dimethyl Sulfoxide results in increased expression of CD14 protein CTD PMID:26036281 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]] CTD PMID:15964820 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd3g CD3g molecule affects expression ISO Dimethyl Sulfoxide affects the expression of CD3G mRNA CTD PMID:24834073 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cd59 CD59 molecule multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased mutagenesis of CD59 gene] CTD PMID:12361925 PMID:15033018 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO Dimethyl Sulfoxide results in decreased expression of CDC25B mRNA CTD PMID:21296123 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdh1 cadherin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of CDH1 mRNA CTD PMID:22193206 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Ceacam19 CEA cell adhesion molecule 19 affects expression ISO Dimethyl Sulfoxide affects the expression of CEACAM19 mRNA CTD PMID:24834073 NCBI chr 1:80,800,951...80,809,769
Ensembl chr 1:80,800,951...80,809,769
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Dimethyl Sulfoxide results in increased expression of CEBPB mRNA CTD PMID:22193206 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cfap300 cilia and flagella associated protein 300 affects expression ISO Dimethyl Sulfoxide affects the expression of CFAP300 mRNA CTD PMID:24834073 NCBI chr 8:6,218,391...6,236,438
Ensembl chr 8:6,218,393...6,235,967
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Dimethyl Sulfoxide affects the expression of CFLAR mRNA CTD PMID:24834073 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CGREF1 mRNA CTD PMID:24834073 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Chek2 checkpoint kinase 2 affects expression ISO Dimethyl Sulfoxide affects the expression of CHEK2 mRNA CTD PMID:24834073 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cklf chemokine-like factor affects expression ISO Dimethyl Sulfoxide affects the expression of CKLF mRNA CTD PMID:24834073 NCBI chr19:903,609...914,880
Ensembl chr19:906,411...914,880
JBrowse link
G Cldn6 claudin 6 multiple interactions
decreases methylation
increases expression
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN6 mRNA]
Dimethyl Sulfoxide results in decreased methylation of CLDN6 promoter
Dimethyl Sulfoxide results in increased expression of CLDN6 mRNA
CTD PMID:18661270 NCBI chr10:12,999,256...13,002,860
Ensembl chr10:13,000,090...13,002,862
JBrowse link
G Cldn8 claudin 8 increases expression ISO Dimethyl Sulfoxide results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
JBrowse link
G Cldn9 claudin 9 multiple interactions
increases expression
decreases methylation
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN9 mRNA]
Dimethyl Sulfoxide results in increased expression of CLDN9 mRNA
Dimethyl Sulfoxide results in decreased methylation of CLDN9 promoter
CTD PMID:18661270 NCBI chr10:13,003,010...13,004,441
Ensembl chr10:13,003,011...13,004,441
JBrowse link
G Cntf ciliary neurotrophic factor affects expression ISO Dimethyl Sulfoxide affects the expression of CNTF mRNA CTD PMID:24834073 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL11A1 mRNA CTD PMID:22193206 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein] CTD PMID:11682029 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL4A1 mRNA CTD PMID:22193206 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col4a5 collagen type IV alpha 5 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL4A5 mRNA CTD PMID:22193206 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL5A1 mRNA CTD PMID:22193206 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cp ceruloplasmin increases expression EXP Dimethyl Sulfoxide results in increased expression of CP mRNA CTD PMID:22193206 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpm carboxypeptidase M increases expression EXP Dimethyl Sulfoxide results in increased expression of CPM mRNA CTD PMID:22193206 NCBI chr 7:60,654,350...60,714,620
Ensembl chr 7:60,654,350...60,714,620
JBrowse link
G Cs citrate synthase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Dimethyl Sulfoxide results in increased expression of CSF1R mRNA CTD PMID:8445950 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cth cystathionine gamma-lyase affects expression ISO Dimethyl Sulfoxide affects the expression of CTH mRNA CTD PMID:24834073 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CTNNB1 protein CTD PMID:20091315 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cuta cutA divalent cation tolerance homolog affects expression ISO Dimethyl Sulfoxide affects the expression of CUTA mRNA CTD PMID:24834073 NCBI chr20:5,532,024...5,533,640
Ensembl chr20:5,532,024...5,533,620
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 affects expression ISO Dimethyl Sulfoxide affects the expression of CXCL14 mRNA CTD PMID:24834073 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxxc4 CXXC finger protein 4 affects expression ISO Dimethyl Sulfoxide affects the expression of CXXC4 mRNA CTD PMID:24834073 NCBI chr 2:239,414,882...239,439,640
Ensembl chr 2:239,415,046...239,439,568
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [adrenocorticotropin zinc results in decreased expression of CYP11B2 mRNA]; Dimethyl Sulfoxide promotes the reaction [adrenocorticotropin zinc results in decreased activity of CYP11B2 protein] CTD PMID:10822027 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of CYP1A1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1A1 protein
Dimethyl Sulfoxide results in increased expression of CYP1A1 mRNA
Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:12147272 PMID:12843640 PMID:22486318 PMID:31096615 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of CYP1A2 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1A2 mRNA
[hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2
CTD PMID:12843640 PMID:18347083 PMID:30262279 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA CTD PMID:12843640 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]] CTD PMID:15964820 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin]
[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]
CTD PMID:19858067 PMID:20371638 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of CYP2B6 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2B6 protein CTD PMID:30262279 PMID:31096615 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA; [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]] CTD PMID:11368792 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
increases expression
increases activity
multiple interactions
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide results in increased activity of CYP2E1 protein
Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]
Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:1538706 PMID:3113478 PMID:3337723 PMID:8074729 PMID:9143349 PMID:12147272 PMID:12843640 PMID:17177172 PMID:19858067 PMID:30262279 PMID:31096615 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP3A5 mRNA CTD PMID:12843640 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP DMSO increases expression of Cyp7a1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cysrt1 cysteine rich tail 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CYSRT1 mRNA CTD PMID:24834073 NCBI chr 3:2,458,295...2,462,037
Ensembl chr 3:2,458,295...2,459,385
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of DDIT3 mRNA CTD PMID:22193206 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Depp1 DEPP1, autophagy regulator affects expression ISO Dimethyl Sulfoxide affects the expression of DEPP1 mRNA CTD PMID:24834073 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases cleavage ISO Dimethyl Sulfoxide results in increased cleavage of DFFA protein CTD PMID:22535522 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dmap1 DNA methyltransferase 1-associated protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of DMAP1 mRNA CTD PMID:24834073 NCBI chr 5:136,533,791...136,541,795
Ensembl chr 5:136,533,792...136,541,795
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression EXP Dimethyl Sulfoxide results in increased expression of DNAJB5 mRNA CTD PMID:22193206 NCBI chr 5:58,393,197...58,402,162
Ensembl chr 5:58,393,233...58,401,870
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP Dimethyl Sulfoxide results in increased expression of DNAJB9 mRNA CTD PMID:22193206 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of DNMT1 protein CTD PMID:17065238 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of DUSP1 mRNA CTD PMID:22193206 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Eaf2 ELL associated factor 2 affects expression ISO Dimethyl Sulfoxide affects the expression of EAF2 mRNA CTD PMID:24834073 NCBI chr11:66,878,658...66,923,092
Ensembl chr11:66,878,658...66,923,092
JBrowse link
G Edn2 endothelin 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of EDN2 mRNA CTD PMID:15619356 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein CTD PMID:20561571 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]
Dimethyl Sulfoxide results in increased expression of EDNRB mRNA; Dimethyl Sulfoxide results in increased expression of EDNRB protein
CTD PMID:20561571 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1akmt1 EEF1A lysine methyltransferase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of EEF1AKMT1 mRNA CTD PMID:24834073 NCBI chr15:37,813,115...37,830,932
Ensembl chr15:37,813,115...37,831,031
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of EFEMP1 mRNA CTD PMID:22193206 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Egr1 early growth response 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of EGR1 mRNA CTD PMID:22193206 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of EIF4G2 protein CTD PMID:18491231 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of EMP1 mRNA CTD PMID:22193206 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Endog endonuclease G affects localization ISO Dimethyl Sulfoxide affects the localization of ENDOG protein CTD PMID:22535522 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of ENPP2 protein CTD PMID:22952646 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Eppin epididymal peptidase inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of EPPIN mRNA CTD PMID:24834073 NCBI chr 3:161,043,761...161,050,550
Ensembl chr 3:161,041,727...161,050,557
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Eva1b eva-1 homolog B affects expression ISO Dimethyl Sulfoxide affects the expression of EVA1B mRNA CTD PMID:24834073 NCBI chr 5:144,160,026...144,161,421
Ensembl chr 5:144,160,108...144,161,410
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Dimethyl Sulfoxide results in increased expression of FAS protein CTD PMID:15998540 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand decreases expression EXP Dimethyl Sulfoxide results in decreased expression of FASLG mRNA CTD PMID:10925121 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxl21 F-box and leucine-rich repeat protein 21 affects expression ISO Dimethyl Sulfoxide affects the expression of FBXL21P mRNA CTD PMID:24834073 NCBI chr17:8,505,771...8,520,208
Ensembl chr17:8,505,996...8,520,147
JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP Dimethyl Sulfoxide results in increased expression of FGG mRNA; Dimethyl Sulfoxide results in increased expression of FGG protein CTD PMID:14757319 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Flnc filamin C increases expression EXP Dimethyl Sulfoxide results in increased expression of FLNC mRNA CTD PMID:22193206 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Dimethyl Sulfoxide results in increased expression of FOS mRNA CTD PMID:22193206 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of FOXA2 mRNA CTD PMID:22105179 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression ISO Dimethyl Sulfoxide affects the expression of FRS3 mRNA CTD PMID:24834073 NCBI chr 9:15,297,794...15,306,850
Ensembl chr 9:15,297,895...15,306,465
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GAD1 mRNA CTD PMID:17065238 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO Dimethyl Sulfoxide affects the expression of GADD45A mRNA CTD PMID:24834073 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP Dimethyl Sulfoxide results in increased expression of GADD45G mRNA CTD PMID:22193206 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Dimethyl Sulfoxide affects the expression of GAPDH mRNA CTD PMID:12843640 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gata4 GATA binding protein 4 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of GATA4 mRNA
Dimethyl Sulfoxide results in increased expression of GATA4 mRNA
CTD PMID:22105179 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of GATA6 mRNA CTD PMID:22105179 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of GJA1 mRNA CTD PMID:22193206 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of GJB1 mRNA CTD PMID:8631141 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of GJB2 mRNA CTD PMID:8631141 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GLT8D1 mRNA CTD PMID:24834073 NCBI chr16:7,082,450...7,097,405
Ensembl chr16:7,082,450...7,097,401
JBrowse link
G Gng3 G protein subunit gamma 3 affects expression ISO Dimethyl Sulfoxide affects the expression of GNG3 mRNA CTD PMID:24834073 NCBI chr 1:225,033,921...225,035,687
Ensembl chr 1:225,033,921...225,035,687
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 decreases expression EXP DMSO decreases expression of Gpbar1 protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 9:81,555,914...81,560,931
Ensembl chr 9:81,559,605...81,560,594
JBrowse link
G Gpr75 G protein-coupled receptor 75 affects expression ISO Dimethyl Sulfoxide affects the expression of GPR75 mRNA CTD PMID:24834073 NCBI chr14:115,270,452...115,278,510
Ensembl chr14:115,275,894...115,278,503
JBrowse link
G Grn granulin precursor increases expression ISO Dimethyl Sulfoxide results in increased expression of GRN mRNA CTD PMID:16873554 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTA1 protein] CTD PMID:12370186 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GSTK1 mRNA CTD PMID:24834073 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein] CTD PMID:12370186 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of GSTM2 mRNA CTD PMID:22193206 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G H3f4 H3.4 histone multiple interactions
decreases methylation
ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H3-4 protein]
Dimethyl Sulfoxide results in decreased methylation of H3-4 protein
CTD PMID:15964820 NCBI chr10:45,304,696...45,305,106 JBrowse link
G H4f16 H4 histone 16 multiple interactions
increases methylation
ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4-16 protein modified form binds to TGM2 gene]; [Dimethyl Sulfoxide co-treated with Alitretinoin] results in increased methylation of H4-16 protein; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4-16 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H4-16 protein]]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide results in increased methylation of H4-16 protein] CTD PMID:15964820 NCBI chr17:43,821,122...43,821,587 JBrowse link
G H4f3 H1.3 linker histone, cluster member affects expression ISO Dimethyl Sulfoxide affects the expression of H1-3 mRNA CTD PMID:24834073 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of HAND1 mRNA
Dimethyl Sulfoxide results in increased expression of HAND1 mRNA
CTD PMID:22105179 NCBI chr10:43,250,729...43,253,296
Ensembl chr10:43,250,745...43,253,296
JBrowse link
G Hbb hemoglobin subunit beta increases expression ISO Dimethyl Sulfoxide results in increased expression of HBB mRNA CTD PMID:21296123 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hcar1 hydroxycarboxylic acid receptor 1 affects expression ISO Dimethyl Sulfoxide affects the expression of HCAR1 mRNA CTD PMID:24834073 NCBI chr12:38,145,177...38,146,232
Ensembl chr12:38,144,855...38,146,271
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of HEXIM1 mRNA; Dimethyl Sulfoxide results in increased expression of HEXIM1 protein CTD PMID:16222702 NCBI chr10:91,200,874...91,202,986
Ensembl chr10:91,200,874...91,202,984
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression EXP Dimethyl Sulfoxide results in increased expression of HIF1A mRNA CTD PMID:22193206 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 affects expression ISO Dimethyl Sulfoxide affects the expression of H3C6 mRNA CTD PMID:24834073 NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide results in decreased expression of HMOX1 protein
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]
Dimethyl Sulfoxide results in increased expression of HMOX1 mRNA
CTD PMID:15689417 PMID:22118543 PMID:22193206 PMID:26497626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin increases expression EXP Dimethyl Sulfoxide results in increased expression of HP mRNA; Dimethyl Sulfoxide results in increased expression of HP protein CTD PMID:14757319 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA CTD PMID:12883083 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase affects expression ISO Dimethyl Sulfoxide affects the expression of HRAS mRNA CTD PMID:24834073 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP Dimethyl Sulfoxide results in increased expression of HSPA1A mRNA CTD PMID:22193206 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein] CTD PMID:18539414 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ier2 immediate early response 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of IER2 mRNA CTD PMID:22193206 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein] CTD PMID:21878375 PMID:29594315 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA] CTD PMID:21878375 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Ift81 intraflagellar transport 81 affects expression ISO Dimethyl Sulfoxide affects the expression of IFT81 mRNA CTD PMID:24834073 NCBI chr12:39,420,161...39,507,412
Ensembl chr12:39,423,596...39,506,890
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:21878375 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1B mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased expression of IL1B mRNA
CTD PMID:21878375 PMID:29594315 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of IL1R1 mRNA CTD PMID:21878375 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23a interleukin 23 subunit alpha affects expression ISO Dimethyl Sulfoxide affects the expression of IL23A mRNA CTD PMID:24834073 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA] CTD PMID:23751068 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA] CTD PMID:23751068 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased secretion of IL6 protein
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA]
CTD PMID:9378980 PMID:10022265 PMID:15689417 PMID:21878375 PMID:24296301 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irgm immunity-related GTPase M affects expression ISO Dimethyl Sulfoxide affects the expression of IRGM mRNA CTD PMID:24834073 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO Dimethyl Sulfoxide affects the expression of ISG15 mRNA CTD PMID:24834073 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
ISO [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of ITGAM protein; Dexamethasone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of ITGAM protein]; Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAM protein] CTD PMID:7909661 PMID:15964820 PMID:16617325 PMID:22118543 PMID:26330309 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgax integrin subunit alpha X multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAX protein] CTD PMID:15964820 NCBI chr 1:199,555,560...199,576,948
Ensembl chr 1:199,555,722...199,576,932
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGB2 protein] CTD PMID:15964820 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Dimethyl Sulfoxide results in increased expression of JUN mRNA
Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of JUN mRNA]
CTD PMID:7662713 PMID:22193206 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of KLF2 mRNA CTD PMID:22193206 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf4 Kruppel like factor 4 increases expression EXP Dimethyl Sulfoxide results in increased expression of KLF4 mRNA CTD PMID:22193206 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klhl41 kelch-like family member 41 affects expression ISO Dimethyl Sulfoxide affects the expression of KLHL41 mRNA CTD PMID:24834073 NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
JBrowse link
G Krt15 keratin 15 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of KRT15 mRNA CTD PMID:22105179 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Lama1 laminin subunit alpha 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of LAMA1 mRNA CTD PMID:22193206 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Lamb2 laminin subunit beta 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of LAMB2 mRNA CTD PMID:22193206 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Ldhc lactate dehydrogenase C affects expression ISO Dimethyl Sulfoxide affects the expression of LDHC mRNA CTD PMID:24834073 NCBI chr 1:102,914,875...102,931,843
Ensembl chr 1:102,915,191...102,931,839
JBrowse link
G Lgals1 galectin 1 affects expression ISO Dimethyl Sulfoxide affects the expression of LGALS1 mRNA CTD PMID:24834073 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Llgl2 LLGL scribble cell polarity complex component 2 affects expression ISO Dimethyl Sulfoxide affects the expression of LLGL2 mRNA CTD PMID:24834073 NCBI chr10:104,367,826...104,403,726
Ensembl chr10:104,368,247...104,403,724
JBrowse link
G LOC103690190 histone H2A type 1-E affects expression ISO Dimethyl Sulfoxide affects the expression of H2AC6 mRNA CTD PMID:24834073 NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Lrrc4 leucine rich repeat containing 4 affects expression ISO Dimethyl Sulfoxide affects the expression of LRRC4 mRNA CTD PMID:24834073 NCBI chr 4:56,110,658...56,114,254
Ensembl chr 4:56,110,658...56,114,254
JBrowse link
G Ltc4s leukotriene C4 synthase multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA] CTD PMID:23751068 NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625
JBrowse link
G Lyrm9 LYR motif containing 9 affects expression ISO Dimethyl Sulfoxide affects the expression of LYRM9 mRNA CTD PMID:24834073 NCBI chr10:66,099,478...66,113,559
Ensembl chr10:66,099,531...66,113,559
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA]
CTD PMID:31265865 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
increases expression
ISO cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA] CTD PMID:31265865 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
decreases activity
EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased activity of MAP3K5 protein]
Dimethyl Sulfoxide results in decreased activity of MAP3K5 protein
CTD PMID:12370186 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects expression
multiple interactions
increases expression
ISO Dimethyl Sulfoxide affects the expression of MAPK3 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA]
CTD PMID:24834073 PMID:31265865 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mat1a methionine adenosyltransferase 1A increases activity ISO Dimethyl Sulfoxide results in increased activity of MAT1A protein CTD PMID:8373829 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Mat2a methionine adenosyltransferase 2A increases activity ISO Dimethyl Sulfoxide results in increased activity of MAT2A protein CTD PMID:8373829 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mc1r melanocortin 1 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of MC1R mRNA CTD PMID:24834073 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of MEF2C mRNA
Dimethyl Sulfoxide results in decreased expression of MEF2C mRNA
CTD PMID:22105179 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mettl26 methyltransferase like 26 affects expression ISO Dimethyl Sulfoxide affects the expression of METTL26 mRNA CTD PMID:24834073 NCBI chr10:15,239,753...15,255,054
Ensembl chr10:15,241,590...15,252,413
JBrowse link
G Mfap5 microfibril associated protein 5 affects expression ISO Dimethyl Sulfoxide affects the expression of MFAP5 mRNA CTD PMID:24834073 NCBI chr 4:155,313,671...155,336,228
Ensembl chr 4:155,313,671...155,336,228
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of MMP1 mRNA; Dimethyl Sulfoxide results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
EXP [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]
Dimethyl Sulfoxide results in increased expression of MMP2 protein
CTD PMID:26497626 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Dimethyl Sulfoxide inhibits the reaction [Ethanol results in increased activity of MMP9 protein]
Dimethyl Sulfoxide results in increased expression of MMP9 protein
CTD PMID:17603938 PMID:26497626 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase increases secretion ISO Dimethyl Sulfoxide results in increased secretion of MPO protein CTD PMID:21633126 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrpl43 mitochondrial ribosomal protein L43 affects expression ISO Dimethyl Sulfoxide affects the expression of MRPL43 mRNA CTD PMID:24834073 NCBI chr 1:264,755,537...264,756,404
Ensembl chr 1:264,755,538...264,756,546
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein] CTD PMID:10640773 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of PZP mRNA; Dimethyl Sulfoxide results in increased expression of PZP protein CTD PMID:14757319 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Mxra8 matrix remodeling associated 8 increases expression EXP Dimethyl Sulfoxide results in increased expression of MXRA8 mRNA CTD PMID:22193206 NCBI chr 5:173,288,200...173,292,926
Ensembl chr 5:173,288,447...173,292,929
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Dimethyl Sulfoxide results in decreased expression of MYC mRNA CTD PMID:7798212 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myo1g myosin IG increases expression EXP Dimethyl Sulfoxide results in increased expression of MYO1G mRNA CTD PMID:22193206 NCBI chr14:86,781,243...86,796,393
Ensembl chr14:86,781,202...86,796,378
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NANOG mRNA CTD PMID:22105179 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nefh neurofilament heavy chain decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NEFH mRNA CTD PMID:22105179 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nes nestin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NES mRNA CTD PMID:22105179 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
decreases expression
EXP [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]
Dimethyl Sulfoxide results in decreased expression of NFE2L2 protein
CTD PMID:26497626 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA] CTD PMID:21878375 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA] CTD PMID:21878375 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nmi N-myc (and STAT) interactor affects expression ISO Dimethyl Sulfoxide affects the expression of NMI mRNA CTD PMID:24834073 NCBI chr 3:37,458,891...37,480,984
Ensembl chr 3:37,458,890...37,480,984
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NMRK1 mRNA CTD PMID:24834073 NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NOS2 mRNA CTD PMID:21878375 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch3 notch receptor 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of NOTCH3 mRNA CTD PMID:20713136 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of NQO1 mRNA CTD PMID:22193206 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP DMSO decreases expression of Nr1h4 mRNA and protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nudt1 nudix hydrolase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NUDT1 mRNA CTD PMID:24834073 NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029
JBrowse link
G Ocln occludin increases expression ISO Dimethyl Sulfoxide results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of ORM1 mRNA; Dimethyl Sulfoxide results in increased expression of ORM1 protein CTD PMID:14757319 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Ostn osteocrin affects expression ISO Dimethyl Sulfoxide affects the expression of OSTN mRNA CTD PMID:24834073 NCBI chr11:76,851,923...76,888,140
Ensembl chr11:76,851,322...76,888,178
JBrowse link
G Padi4 peptidyl arginine deiminase 4 multiple interactions
increases expression
ISO Calcimycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of PADI4 protein]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of PADI4 mRNA] CTD PMID:15964820 PMID:29425503 NCBI chr 5:159,260,675...159,293,906
Ensembl chr 5:159,260,675...159,293,673
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha affects expression ISO Dimethyl Sulfoxide affects the expression of PARD6A mRNA CTD PMID:24834073 NCBI chr19:37,668,133...37,670,450
Ensembl chr19:37,668,133...37,672,729
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Dimethyl Sulfoxide results in increased cleavage of PARP1 protein CTD PMID:22535522 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of PDCD4 protein CTD PMID:17259349 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Phf6 PHD finger protein 6 affects expression ISO Dimethyl Sulfoxide affects the expression of PHF6 mRNA CTD PMID:24834073 NCBI chr  X:158,698,353...158,739,855
Ensembl chr  X:158,698,356...158,739,838
Ensembl chr  X:158,698,356...158,739,838
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing affects expression ISO Dimethyl Sulfoxide affects the expression of PIKFYVE mRNA CTD PMID:24834073 NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838
JBrowse link
G Pjvk pejvakin affects expression ISO Dimethyl Sulfoxide affects the expression of PJVK mRNA CTD PMID:24834073 NCBI chr 3:63,508,386...63,518,163
Ensembl chr 3:63,510,293...63,518,147
JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PLA2G2A mRNA CTD PMID:21878375 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PLEKHF1 mRNA CTD PMID:24834073 NCBI chr 1:94,609,041...94,616,565
Ensembl chr 1:94,609,377...94,610,854
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of PLOD2 mRNA CTD PMID:22193206 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Pomc proopiomelanocortin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of POMC protein CTD PMID:15680486 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
decreases activity
ISO Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical]
Dimethyl Sulfoxide results in decreased activity of POR protein
Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Dimethyl Sulfoxide promotes the reaction [Hemin results in decreased activity of POR protein]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide results in decreased activity of POR protein]
CTD PMID:11368792 PMID:21215309 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pot1 protection of telomeres 1 multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; [Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA CTD PMID:26330309 NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
JBrowse link
G Pou5f1 POU class 5 homeobox 1 affects expression ISO Dimethyl Sulfoxide affects the expression of POU5F1 mRNA CTD PMID:24834073 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARA mRNA CTD PMID:21878375 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARG mRNA CTD PMID:21878375 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Pqbp1 polyglutamine binding protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PQBP1 mRNA CTD PMID:24834073 NCBI chr  X:15,448,570...15,453,130
Ensembl chr  X:15,348,138...15,453,130
JBrowse link
G Prmt1 protein arginine methyltransferase 1 multiple interactions ISO PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]] CTD PMID:31877331 NCBI chr 1:100,971,132...100,980,411
Ensembl chr 1:100,971,273...100,980,340
JBrowse link
G Prph peripherin affects expression ISO Dimethyl Sulfoxide affects the expression of PRPH mRNA CTD PMID:24834073 NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197
JBrowse link
G Ptgds prostaglandin D2 synthase multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA] CTD PMID:23751068 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PTGS1 mRNA CTD PMID:21878375 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Dimethyl Sulfoxide results in increased expression of PTGS2 protein
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein]
CTD PMID:21878375 PMID:23751068 PMID:26497626 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pxdn peroxidasin increases expression EXP Dimethyl Sulfoxide results in increased expression of PXDN mRNA CTD PMID:22193206 NCBI chr 6:48,866,496...48,982,368
Ensembl chr 6:48,866,601...48,980,340
JBrowse link
G Rab3c RAB3C, member RAS oncogene family affects expression ISO Dimethyl Sulfoxide affects the expression of RAB3C mRNA CTD PMID:24834073 NCBI chr 2:41,570,955...41,786,681
Ensembl chr 2:41,570,597...41,785,792
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of RAF1 mRNA CTD PMID:31265865 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Reln reelin increases expression ISO Dimethyl Sulfoxide results in increased expression of RELN mRNA CTD PMID:17065238 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Rfx3 regulatory factor X3 affects expression ISO Dimethyl Sulfoxide affects the expression of RFX3 mRNA CTD PMID:24834073 NCBI chr 1:245,853,332...246,110,648
Ensembl chr 1:245,859,633...246,110,218
JBrowse link
G RGD1309036 hypothetical LOC292874 affects expression ISO Dimethyl Sulfoxide affects the expression of C19ORF81 mRNA CTD PMID:24834073 NCBI chr 1:100,346,096...100,361,340
Ensembl chr 1:100,346,096...100,359,511
JBrowse link
G RGD1309540 similar to hypothetical protein MGC40841; similar to hypothetical protein MGC4707 affects expression ISO Dimethyl Sulfoxide affects the expression of C11ORF49 mRNA CTD PMID:24834073 NCBI chr 3:80,092,589...80,349,249
Ensembl chr 3:80,095,042...80,349,145
JBrowse link
G RGD1309651 similar to 1190005I06Rik protein affects expression ISO Dimethyl Sulfoxide affects the expression of C16ORF74 mRNA CTD PMID:24834073 NCBI chr19:54,184,554...54,210,872
Ensembl chr19:54,184,946...54,210,515
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression ISO Dimethyl Sulfoxide affects the expression of RNASE4 mRNA CTD PMID:24834073 NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389
Ensembl chr15:28,018,040...28,035,389
JBrowse link
G Rnf152 ring finger protein 152 affects expression ISO Dimethyl Sulfoxide affects the expression of RNF152 mRNA CTD PMID:24834073 NCBI chr13:25,183,295...25,262,785
Ensembl chr13:25,186,106...25,262,469
JBrowse link
G RT1-Da RT1 class II, locus Da decreases expression ISO Dimethyl Sulfoxide results in decreased expression of HLA-DRA mRNA CTD PMID:21878375 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G Rxra retinoid X receptor alpha increases expression
affects response to substance
ISO Dimethyl Sulfoxide results in increased expression of RXRA mRNA; Dimethyl Sulfoxide results in increased expression of RXRA protein
RXRA protein affects the susceptibility to Dimethyl Sulfoxide
CTD PMID:9751115 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression ISO Dimethyl Sulfoxide results in decreased expression of RXRG protein CTD PMID:9751115 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G S100a13 S100 calcium binding protein A13 affects expression ISO Dimethyl Sulfoxide affects the expression of S100A13 mRNA CTD PMID:24834073 NCBI chr 2:189,906,022...189,912,516
Ensembl chr 2:189,906,022...189,912,516
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A8 mRNA CTD PMID:1733233 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A9 mRNA CTD PMID:1733233 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Sdhaf4 succinate dehydrogenase complex assembly factor 4 affects expression ISO Dimethyl Sulfoxide affects the expression of SDHAF4 mRNA CTD PMID:24834073 NCBI chr 9:30,243,261...30,251,478
Ensembl chr 9:30,243,610...30,251,388
JBrowse link
G Selenbp1 selenium binding protein 1 increases abundance ISO SELENBP1 gene mutant form results in increased abundance of Dimethyl Sulfoxide CTD PMID:29255262 NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SERP2 mRNA CTD PMID:24834073 NCBI chr15:58,687,784...58,712,023
Ensembl chr15:58,687,786...58,711,872
JBrowse link
G Slc24a2 solute carrier family 24 member 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of SLC24A2 mRNA CTD PMID:22193206 NCBI chr 5:105,336,287...105,579,959
Ensembl chr 5:105,336,262...105,582,375
JBrowse link
G Slc24a4 solute carrier family 24 member 4 increases expression EXP Dimethyl Sulfoxide results in increased expression of SLC24A4 mRNA CTD PMID:22193206 NCBI chr 6:126,015,799...126,158,727
Ensembl chr 6:126,018,841...126,153,867
JBrowse link
G Slc2a6 solute carrier family 2 member 6 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC2A6 mRNA CTD PMID:24834073 NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136
JBrowse link
G Slc35e4 solute carrier family 35, member E4 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC35E4 mRNA CTD PMID:24834073 NCBI chr14:84,163,971...84,170,835
Ensembl chr14:84,163,972...84,170,835
JBrowse link
G Snx15 sorting nexin 15 affects expression ISO Dimethyl Sulfoxide affects the expression of SNX15 mRNA CTD PMID:24834073 NCBI chr 1:221,487,058...221,496,200
Ensembl chr 1:221,487,051...221,496,306
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of SOD3 mRNA CTD PMID:22193206 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of SORD protein] CTD PMID:17177172 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of SOX17 mRNA CTD PMID:22105179 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SPINK2 mRNA CTD PMID:24834073 NCBI chr14:33,247,278...33,253,913
Ensembl chr14:33,247,274...33,253,913
Ensembl chr14:33,247,274...33,253,913
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP DMSO increases expression of Srebf1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of SRXN1 mRNA CTD PMID:22193206 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 affects expression ISO Dimethyl Sulfoxide affects the expression of STAC3 mRNA CTD PMID:24834073 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA CTD PMID:31265865 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] CTD PMID:14570759 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects expression ISO Dimethyl Sulfoxide affects the expression of SUMO1 mRNA CTD PMID:24834073 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Syce2 synaptonemal complex central element protein 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SYCE2 mRNA CTD PMID:24834073 NCBI chr19:25,982,003...26,002,399
Ensembl chr19:25,983,169...26,001,317
JBrowse link
G Tas2r103 taste receptor, type 2, member 103 affects expression ISO Dimethyl Sulfoxide affects the expression of TAS2R14 mRNA CTD PMID:24834073 NCBI chr 4:167,179,587...167,203,109
Ensembl chr 4:167,179,718...167,180,656
JBrowse link
G Tatdn1 TatD DNase domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of TATDN1 mRNA CTD PMID:24834073 NCBI chr 7:98,782,164...98,813,001
Ensembl chr 7:98,782,178...98,804,499
JBrowse link
G Terc telomerase RNA component multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA CTD PMID:26330309 NCBI chr 2:116,432,723...116,433,110
Ensembl chr 2:116,432,691...116,433,110
JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA CTD PMID:26330309 NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668
JBrowse link
G Terf2 telomeric repeat binding factor 2 multiple interactions ISO [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dimethyl Sulfoxide co-treated with Tretinoin] results in decreased expression of TERF2 mRNA; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF2 mRNA CTD PMID:26330309 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
ISO Dimethyl Sulfoxide results in decreased expression of TERT mRNA
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA
CTD PMID:16180984 PMID:26330309 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tf transferrin increases expression EXP Dimethyl Sulfoxide results in increased expression of TF mRNA CTD PMID:22193206 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfpi tissue factor pathway inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of TFPI mRNA CTD PMID:24834073 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4-16 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]] CTD PMID:15964820 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] CTD PMID:11682029 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tirap TIR domain containing adaptor protein affects expression ISO Dimethyl Sulfoxide affects the expression of TIRAP mRNA CTD PMID:24834073 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tmem121 transmembrane protein 121 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM121 mRNA CTD PMID:24834073 NCBI chr 6:137,994,675...138,002,897
Ensembl chr 6:137,997,335...137,998,291
JBrowse link
G Tmem134 transmembrane protein 134 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM134 mRNA CTD PMID:24834073 NCBI chr 1:219,374,005...219,383,365
Ensembl chr 1:219,374,060...219,379,557
JBrowse link
G Tmem150c transmembrane protein 150C affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM150C mRNA CTD PMID:24834073 NCBI chr14:11,094,655...11,166,323
Ensembl chr14:11,095,163...11,166,428
JBrowse link
G Tmem266 transmembrane protein 266 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM266 mRNA CTD PMID:24834073 NCBI chr 8:59,952,732...60,014,363
Ensembl chr 8:59,900,651...60,014,363
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [ferrous sulfate promotes the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]]
Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]
CTD PMID:7539275 PMID:14576080 PMID:21878375 PMID:22319556 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP Dimethyl Sulfoxide results in increased expression of TNFRSF12A mRNA CTD PMID:22193206 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] CTD PMID:9870925 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 affects expression ISO Dimethyl Sulfoxide affects the expression of TOMM5 mRNA CTD PMID:24834073 NCBI chr 5:60,655,708...60,658,568
Ensembl chr 5:60,655,379...60,658,535
JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of TPM3 mRNA CTD PMID:22193206 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Tra2b transformer 2 beta homolog increases expression EXP Dimethyl Sulfoxide results in increased expression of TRA2B mRNA CTD PMID:22193206 NCBI chr11:82,373,828...82,392,208
Ensembl chr11:82,373,870...82,392,083
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of TRIB3 mRNA CTD PMID:22193206 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 affects expression ISO Dimethyl Sulfoxide affects the expression of TSC22D3 mRNA CTD PMID:24834073 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tsnare1 t-SNARE domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of TSNARE1 mRNA CTD PMID:24834073 NCBI chr 7:115,576,084...115,662,590 JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO Dimethyl Sulfoxide results in decreased expression of TUBB3 mRNA CTD PMID:22105179 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G U2af1l4 U2 small nuclear RNA auxiliary factor 1-like 4 affects expression ISO Dimethyl Sulfoxide affects the expression of U2AF1L4 mRNA CTD PMID:24834073 NCBI chr 1:89,017,414...89,019,651
Ensembl chr 1:89,017,479...89,019,937
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C affects expression ISO Dimethyl Sulfoxide affects the expression of UBE2C mRNA CTD PMID:24834073 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ufsp1 UFM1-specific peptidase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of UFSP1 mRNA CTD PMID:24834073 NCBI chr12:22,471,141...22,472,357
Ensembl chr12:22,471,391...22,472,044
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A6 mRNA CTD PMID:12843640 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A9 mRNA CTD PMID:12843640 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Upk3b uroplakin 3B affects expression ISO Dimethyl Sulfoxide affects the expression of UPK3B mRNA CTD PMID:24834073 NCBI chr12:23,676,169...23,682,395
Ensembl chr12:23,676,152...23,682,381
JBrowse link
G Uts2r urotensin 2 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of UTS2R mRNA CTD PMID:24834073 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Vom1r10 vomeronasal 1 receptor 10 affects expression ISO Dimethyl Sulfoxide affects the expression of VN1R2 mRNA CTD PMID:24834073 NCBI chr 1:60,280,451...60,281,386
Ensembl chr 1:60,280,451...60,281,386
JBrowse link
G Wapl WAPL cohesin release factor increases expression ISO Dimethyl Sulfoxide results in increased expression of WAPL mRNA CTD PMID:15797623 NCBI chr16:11,029,325...11,108,867
Ensembl chr16:11,032,531...11,106,589
JBrowse link
G Wnt11 Wnt family member 11 affects expression ISO Dimethyl Sulfoxide affects the expression of WNT11 mRNA CTD PMID:24834073 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Zfp36 zinc finger protein 36 affects expression ISO Dimethyl Sulfoxide affects the expression of ZFP36 mRNA CTD PMID:24834073 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
edrophonium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO Edrophonium binds to and results in decreased activity of ACHE protein; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [cyclohexyl methylphosphonofluoridate results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [Obidoxime Chloride metabolite results in decreased activity of ACHE protein]; Edrophonium promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]
Edrophonium results in decreased activity of ACHE protein
CTD PMID:25522658 PMID:27297626 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO Edrophonium binds to and results in decreased activity of BCHE protein CTD PMID:31173753 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
ferric ammonium citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
decreases activity
ISO ferric ammonium citrate results in increased activity of ACO1 protein
ferric ammonium citrate results in decreased activity of ACO1 protein
CTD PMID:11054110 PMID:18073202 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 multiple interactions
increases activity
ISO ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]; ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein]
ferric ammonium citrate results in increased activity of ACO2 protein
CTD PMID:16625280 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] CTD PMID:32283200 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of ALB protein] CTD PMID:24862973 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Anxa3 annexin A3 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein] CTD PMID:19515424 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein] CTD PMID:19515424 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO ferric ammonium citrate results in increased cleavage of CASP3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:17191120 PMID:26318285 PMID:27481217 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] CTD PMID:12807743 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO ferric ammonium citrate results in decreased expression of COL1A1 mRNA CTD PMID:19735707 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases phosphorylation
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Cyclosporine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; ferric ammonium citrate results in decreased phosphorylation of and affects the localization of DNM1L protein; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:26318285 PMID:27481217 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Erp29 endoplasmic reticulum protein 29 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein] CTD PMID:19515424 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G F3 coagulation factor III, tissue factor increases expression
multiple interactions
ISO ferric ammonium citrate results in increased expression of F3 mRNA
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA]
CTD PMID:25858758 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein] CTD PMID:32283200 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
increases expression
ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of FTL mRNA
ferric ammonium citrate results in increased expression of FTL1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:12393473 PMID:19913091 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein] CTD PMID:19515424 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein] CTD PMID:19515424 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
ISO Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of HMOX1 protein
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ferric ammonium citrate results in increased expression of HMOX1 protein]
CTD PMID:12393473 PMID:16439612 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein] CTD PMID:19515424 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein] CTD PMID:19515424 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL1B protein] CTD PMID:24862973 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of IL6 protein] CTD PMID:24862973 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] CTD PMID:32283200 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases expression
decreases activity
EXP
ISO
ferric ammonium citrate results in decreased expression of IREB2 protein
ferric ammonium citrate results in decreased activity of IREB2 protein
CTD PMID:11054110 PMID:17469137 PMID:18073202 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [bathophenanthroline disulfonic acid results in decreased expression of LCN2 protein] CTD PMID:17350462 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK1 protein
ferric ammonium citrate results in increased phosphorylation of MAPK1 protein
CTD PMID:17191120 PMID:25858758 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO ferric ammonium citrate results in increased phosphorylation of MAPK14 protein CTD PMID:17191120 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK3 protein
ferric ammonium citrate results in increased phosphorylation of MAPK3 protein
CTD PMID:17191120 PMID:25858758 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 9:49,647,257...49,704,828
Ensembl chr 9:49,647,257...49,704,828
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 NCBI chr16:8,302,950...8,323,294
Ensembl chr16:8,302,950...8,323,293
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA] CTD PMID:9826428 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Oga O-GlcNAcase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of OGA protein] CTD PMID:24862973 NCBI chr 1:265,506,752...265,542,452
Ensembl chr 1:265,507,451...265,542,276
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein] CTD PMID:19515424 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein] CTD PMID:19515424 NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein] CTD PMID:19515424 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein] CTD PMID:19515424 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of PTGS2 mRNA] CTD PMID:24862973 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein] CTD PMID:19515424 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Slc11a1 solute carrier family 11 member 1 increases expression ISO ferric ammonium citrate results in increased expression of SLC11A1 mRNA CTD PMID:11054110 NCBI chr 9:81,655,590...81,666,697
Ensembl chr 9:81,655,629...81,666,706
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression ISO ferric ammonium citrate results in increased expression of SLC11A2 mRNA CTD PMID:11054110 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of SLC40A1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:19913091 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of SOD1 mRNA] CTD PMID:24862973 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Tf transferrin multiple interactions ISO ferric ammonium citrate inhibits the reaction [TF protein results in increased uptake of Iron] CTD PMID:11335103 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO ferric ammonium citrate results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr12:22,177,382...22,194,330
Ensembl chr12:22,177,382...22,194,299
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO ferric ammonium citrate results in decreased expression of TFRC mRNA; ferric ammonium citrate results in decreased expression of TFRC protein
[ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of TFRC mRNA
CTD PMID:11054110 PMID:12393473 PMID:16760464 PMID:18073202 PMID:25633564 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of TNF protein] CTD PMID:24862973 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tpd52l1 TPD52 like 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein] CTD PMID:19515424 NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein] CTD PMID:19515424 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
fluorescein (lactone form) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO [CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein; Tranylcypromine inhibits the reaction [[CYP2C19 protein results in increased metabolism of dibenzylfluorescein] which results in increased chemical synthesis of Fluorescein] CTD PMID:23850985 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Fluorescein results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Fluorescein inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases uptake
multiple interactions
ISO SLCO1B3 protein results in increased uptake of Fluorescein
bisphenol A inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; bisphenol F promotes the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; Probenecid inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]; tetrabromobisphenol A inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein]
CTD PMID:27989701 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Slco3a1 solute carrier organic anion transporter family, member 3a1 increases uptake
multiple interactions
ISO SLCO3A1 protein results in increased uptake of Fluorescein
Cyclosporine promotes the reaction [SLCO3A1 protein results in increased uptake of Fluorescein]; simvastatin acid affects the reaction [SLCO3A1 protein results in increased uptake of Fluorescein]
CTD PMID:28887287 NCBI chr 1:135,790,854...136,073,640
Ensembl chr 1:135,790,810...136,073,540
JBrowse link
fluorescein 5-isothiocyanate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 affects binding ISO Fluorescein-5-isothiocyanate binds to ABCB7 protein CTD PMID:27129696 NCBI chr  X:75,150,511...75,291,950
Ensembl chr  X:75,150,608...75,291,938
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Anxa4 annexin A4 affects binding ISO Fluorescein-5-isothiocyanate binds to ANXA4 protein CTD PMID:27129696 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Arhgap6 Rho GTPase activating protein 6 affects binding ISO Fluorescein-5-isothiocyanate binds to ARHGAP6 protein CTD PMID:27129696 NCBI chr  X:26,314,561...26,845,242
Ensembl chr  X:26,315,878...26,376,467
JBrowse link
G Azi2 5-azacytidine induced 2 affects binding ISO Fluorescein-5-isothiocyanate binds to AZI2 protein CTD PMID:27129696 NCBI chr 8:126,411,030...126,435,581
Ensembl chr 8:126,411,829...126,434,579
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta affects binding ISO Fluorescein-5-isothiocyanate binds to CAPZB protein CTD PMID:27129696 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Cd109 CD109 molecule affects binding ISO Fluorescein-5-isothiocyanate binds to CD109 protein CTD PMID:27129696 NCBI chr 8:85,951,420...86,065,411
Ensembl chr 8:85,951,191...86,065,409
JBrowse link
G Cd180 CD180 molecule affects binding ISO Fluorescein-5-isothiocyanate binds to CD180 protein CTD PMID:27129696 NCBI chr 2:32,820,275...32,833,223
Ensembl chr 2:32,820,322...32,833,125
JBrowse link
G Cd86 CD86 molecule increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cd93 CD93 molecule affects binding ISO Fluorescein-5-isothiocyanate binds to CD93 protein CTD PMID:27129696 NCBI chr 3:142,778,798...142,783,774
Ensembl chr 3:142,778,770...142,783,774
JBrowse link
G Cdc20 cell division cycle 20 affects binding ISO Fluorescein-5-isothiocyanate binds to CDC20 protein CTD PMID:27129696 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Copa COPI coat complex subunit alpha affects binding ISO Fluorescein-5-isothiocyanate binds to COPA protein CTD PMID:27129696 NCBI chr13:90,467,285...90,508,894
Ensembl chr13:90,467,265...90,508,932
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Dcaf4 DDB1 and CUL4 associated factor 4 affects binding ISO Fluorescein-5-isothiocyanate binds to DCAF4 protein CTD PMID:27129696 NCBI chr 6:107,001,763...107,027,466
Ensembl chr 6:107,001,763...107,027,456
JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase affects binding ISO Fluorescein-5-isothiocyanate binds to DOT1L protein CTD PMID:27129696 NCBI chr 7:11,786,105...11,824,742
Ensembl chr 7:11,786,105...11,824,742
JBrowse link
G Elac1 elaC ribonuclease Z 1 affects binding ISO Fluorescein-5-isothiocyanate binds to ELAC1 protein CTD PMID:27129696 NCBI chr18:69,706,522...69,723,869
Ensembl chr18:69,706,522...69,723,869
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 affects binding ISO Fluorescein-5-isothiocyanate binds to ENPP7 protein CTD PMID:27129696 NCBI chr10:108,095,131...108,099,483
Ensembl chr10:108,095,131...108,099,483
JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 affects binding ISO Fluorescein-5-isothiocyanate binds to FLRT3 protein CTD PMID:27129696 NCBI chr 3:134,684,446...134,696,586
Ensembl chr 3:134,683,065...134,696,654
JBrowse link
G Fn1 fibronectin 1 affects binding ISO Fluorescein-5-isothiocyanate binds to FN1 protein CTD PMID:27129696 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased expression of HMOX1 protein
[Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of HMOX1 protein
CTD PMID:27871981 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects binding ISO Fluorescein-5-isothiocyanate binds to HSPA5 protein CTD PMID:27129696 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects binding ISO Fluorescein-5-isothiocyanate binds to HSPA9 protein CTD PMID:27129696 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IFNG protein CTD PMID:29198882 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects binding ISO Fluorescein-5-isothiocyanate binds to IKBKB protein CTD PMID:27129696 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Ikzf4 IKAROS family zinc finger 4 affects binding ISO Fluorescein-5-isothiocyanate binds to IKZF4 protein CTD PMID:27129696 NCBI chr 7:3,061,422...3,098,142
Ensembl chr 7:3,061,469...3,074,359
JBrowse link
G Il17re interleukin 17 receptor E affects binding ISO Fluorescein-5-isothiocyanate binds to IL17RE protein CTD PMID:27129696 NCBI chr 4:145,413,157...145,426,608
Ensembl chr 4:145,413,230...145,426,603
JBrowse link
G Il31ra interleukin 31 receptor A affects binding ISO Fluorescein-5-isothiocyanate binds to IL31RA protein CTD PMID:27129696 NCBI chr 2:44,333,347...44,408,005
Ensembl chr 2:44,336,006...44,394,709
JBrowse link
G Il4 interleukin 4 multiple interactions
increases expression
ISO [Dibutyl Phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; [dibutyrylglycerol analog co-treated with Fluorescein-5-isothiocyanate] affects the secretion of IL4 protein; [tributyrin co-treated with Fluorescein-5-isothiocyanate] results in increased secretion of IL4 protein; diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of IL4 protein]] CTD PMID:27871981 PMID:29198882 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 affects binding ISO Fluorescein-5-isothiocyanate binds to LYPD3 protein CTD PMID:27129696 NCBI chr 1:81,499,856...81,504,306
Ensembl chr 1:81,499,821...81,504,318
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of MAFF mRNA CTD PMID:20491607 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 affects binding ISO Fluorescein-5-isothiocyanate binds to MAP3K20 protein CTD PMID:27129696 NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK1 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK1 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD PMID:27129696 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK3 protein
Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK3 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
CTD PMID:27129696 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein
CTD PMID:27129696 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
ISO Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK9 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]
Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK9 protein
CTD PMID:27129696 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mybpc1 myosin binding protein C1 affects binding ISO Fluorescein-5-isothiocyanate binds to MYBPC1 protein CTD PMID:27129696 NCBI chr 7:29,086,159...29,171,909
Ensembl chr 7:29,086,156...29,171,783
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO [Melatonin co-treated with diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased expression of NFE2L2 protein CTD PMID:27871981 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased expression of NQO1 mRNA
Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein
diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]; Melatonin inhibits the reaction [diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]]
CTD PMID:20491607 PMID:27871981 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Plce1 phospholipase C, epsilon 1 affects binding ISO Fluorescein-5-isothiocyanate binds to PLCE1 protein CTD PMID:27129696 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
JBrowse link
G Postn periostin affects binding ISO Fluorescein-5-isothiocyanate binds to POSTN protein CTD PMID:27129696 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Pprc1 PPARG related coactivator 1 affects binding ISO Fluorescein-5-isothiocyanate binds to PPRC1 protein CTD PMID:27129696 NCBI chr 1:265,809,892...265,826,319
Ensembl chr 1:265,809,754...265,826,306
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of PRKCB protein CTD PMID:31958493 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Psd4 pleckstrin and Sec7 domain containing 4 affects binding ISO Fluorescein-5-isothiocyanate binds to PSD4 protein CTD PMID:27129696 NCBI chr 3:1,478,432...1,515,094
Ensembl chr 3:1,478,525...1,514,934
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 affects binding ISO Fluorescein-5-isothiocyanate binds to PSMD14 protein CTD PMID:27129696 NCBI chr 3:47,578,449...47,673,330
Ensembl chr 3:47,578,384...47,673,338
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein; Melatonin inhibits the reaction [[diisodecyl phthalate co-treated with Fluorescein-5-isothiocyanate] results in increased phosphorylation of RELA protein] CTD PMID:27871981 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 affects binding ISO Fluorescein-5-isothiocyanate binds to SCN5A protein CTD PMID:27129696 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Skor1 SKI family transcriptional corepressor 1 affects binding ISO Fluorescein-5-isothiocyanate binds to SKOR1 protein CTD PMID:27129696 NCBI chr 8:68,029,930...68,040,504
Ensembl chr 8:68,030,621...68,038,533
JBrowse link
G Slc38a10 solute carrier family 38, member 10 affects binding ISO Fluorescein-5-isothiocyanate binds to SLC38A10 protein CTD PMID:27129696 NCBI chr10:109,284,054...109,333,907
Ensembl chr10:109,284,957...109,333,899
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases phosphorylation
ISO diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT3 protein]] CTD PMID:27871981 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions
increases phosphorylation
ISO diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT5 protein]] CTD PMID:27871981 NCBI chr10:88,764,732...88,789,060
Ensembl chr10:88,764,732...88,789,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases phosphorylation
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased phosphorylation of STAT6 protein]]
CTD PMID:27871981 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 affects binding ISO Fluorescein-5-isothiocyanate binds to TRPA1 protein CTD PMID:27129696 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
ISO Fluorescein-5-isothiocyanate results in increased expression of TSLP protein
diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]; Melatonin inhibits the reaction [diisodecyl phthalate promotes the reaction [Fluorescein-5-isothiocyanate results in increased expression of TSLP protein]]
CTD PMID:27871981 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Fluorescein-5-isothiocyanate results in increased expression of TXN mRNA CTD PMID:20491607 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Usp3 ubiquitin specific peptidase 3 affects binding ISO Fluorescein-5-isothiocyanate binds to USP3 protein CTD PMID:27129696 NCBI chr 8:72,207,970...72,284,871
Ensembl chr 8:72,207,972...72,284,873
JBrowse link
gadodiamide hydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO gadodiamide results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein]
CTD PMID:19561517 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO gadodiamide results in increased expression of ALDH1A1 mRNA CTD PMID:20959327 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO gadodiamide results in increased expression of ANKRD22 mRNA CTD PMID:20959327 NCBI chr 1:252,430,750...252,461,346
Ensembl chr 1:252,429,677...252,461,461
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO gadodiamide results in increased expression of ATM mRNA CTD PMID:20959327 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO gadodiamide results in increased expression of ATP8B1 mRNA CTD PMID:20959327 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
ISO
EXP
gadodiamide results in increased expression of CCL2 mRNA
gadodiamide results in increased expression of CCL2 mRNA; gadodiamide results in increased expression of CCL2 protein
gadodiamide results in increased secretion of CCL2 protein
CTD PMID:20938346 PMID:20959327 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression EXP gadodiamide results in increased expression of CCL4 protein CTD PMID:20938346 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP gadodiamide results in increased expression of CCL7 protein CTD PMID:20938346 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
increases secretion
ISO
EXP
gadodiamide results in increased expression of CXCL10 mRNA
gadodiamide results in increased expression of CXCL10 protein
gadodiamide results in increased secretion of CXCL10 protein
CTD PMID:20938346 PMID:20959327 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases secretion
increases expression
ISO gadodiamide results in increased secretion of CXCL11 protein
gadodiamide results in increased expression of CXCL11 mRNA
CTD PMID:20959327 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO gadodiamide results in increased expression of CXCL12 mRNA CTD PMID:20959327 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO gadodiamide results in increased expression of CXCL9 mRNA CTD PMID:20959327 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO gadodiamide results in increased expression of IDO1 mRNA CTD PMID:20959327 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO gadodiamide results in increased expression of IFI44L mRNA CTD PMID:20959327 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO gadodiamide results in increased expression of IFIT3 mRNA CTD PMID:20959327 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma increases expression ISO gadodiamide results in increased expression of IFNG mRNA; gadodiamide results in increased expression of IFNG protein CTD PMID:19404939 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il13 interleukin 13 increases expression ISO gadodiamide results in increased expression of IL13 mRNA; gadodiamide results in increased expression of IL13 protein CTD PMID:19404939 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP gadodiamide results in increased expression of IL1A protein CTD PMID:20938346 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il4 interleukin 4 increases expression
affects expression
ISO gadodiamide results in increased expression of IL4 protein
gadodiamide affects the expression of IL4 mRNA
CTD PMID:19404939 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4i1 interleukin 4 induced 1 increases expression ISO gadodiamide results in increased expression of IL4I1 mRNA CTD PMID:20959327 NCBI chr 1:100,811,727...100,836,901
Ensembl chr 1:100,830,064...100,836,677
JBrowse link
G Il6 interleukin 6 affects expression
increases expression
ISO gadodiamide affects the expression of IL6 protein
gadodiamide results in increased expression of IL6 mRNA
CTD PMID:19404939 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kitlg KIT ligand increases expression EXP gadodiamide results in increased expression of KITLG protein CTD PMID:20938346 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein] CTD PMID:19561517 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein] CTD PMID:19561517 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]
gadodiamide results in increased expression of MMP1 mRNA; gadodiamide results in increased expression of MMP1 protein
CTD PMID:19561517 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO gadodiamide results in increased expression of NOS2 protein CTD PMID:20959327 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nxpe3 neurexophilin and PC-esterase domain family, member 3 increases expression ISO gadodiamide results in increased expression of NXPE3 mRNA CTD PMID:20959327 NCBI chr11:47,188,332...47,238,372
Ensembl chr11:47,188,495...47,238,372
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization ISO gadodiamide results in increased localization of RELA protein CTD PMID:20959327 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1306063 similar to HT021 increases expression ISO gadodiamide results in increased expression of C3ORF14 mRNA CTD PMID:20959327 NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
JBrowse link
G Rhoq ras homolog family member Q increases expression ISO gadodiamide results in increased expression of RHOQ mRNA CTD PMID:20959327 NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO gadodiamide results in increased expression of RIT1 mRNA CTD PMID:20959327 NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
JBrowse link
G Rnf125 ring finger protein 125 increases expression ISO gadodiamide results in increased expression of RNF125 mRNA CTD PMID:20959327 NCBI chr18:15,193,226...15,225,454
Ensembl chr18:15,192,962...15,225,427
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO gadodiamide results in increased expression of RSAD2 mRNA CTD PMID:20959327 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Slc39a10 solute carrier family 39 member 10 increases expression ISO gadodiamide results in increased expression of SLC39A10 mRNA CTD PMID:20959327 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Spn sialophorin increases expression ISO gadodiamide results in increased expression of SPN mRNA CTD PMID:20959327 NCBI chr 1:198,572,999...198,585,664
Ensembl chr 1:198,572,999...198,577,226
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP gadodiamide results in increased expression of SPP1 protein CTD PMID:20938346 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO
EXP
gadodiamide results in increased expression of TGFB1 mRNA; gadodiamide results in increased expression of TGFB1 protein CTD PMID:19404939 PMID:20938346 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO
EXP
gadodiamide results in increased expression of TIMP1 mRNA; gadodiamide results in increased expression of TIMP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]
CTD PMID:19561517 PMID:20938346 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Ubd ubiquitin D increases expression ISO gadodiamide results in increased expression of UBD mRNA CTD PMID:20959327 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP
gadodiamide results in increased expression of VEGFA mRNA; gadodiamide results in increased expression of VEGFA protein CTD PMID:19404939 PMID:20938346 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO gadodiamide results in increased expression of WDR5 mRNA CTD PMID:20959327 NCBI chr 3:6,061,892...6,080,724
Ensembl chr 3:6,061,940...6,080,680
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO gadodiamide results in increased expression of XIAP mRNA CTD PMID:20959327 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Zfp652 zinc finger protein 652 increases expression ISO gadodiamide results in increased expression of ZNF652 mRNA CTD PMID:20959327 NCBI chr10:83,556,809...83,572,014
Ensembl chr10:83,556,809...83,572,019
JBrowse link
iodixanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 increases expression EXP iodixanol results in increased expression of EDN1 protein CTD PMID:21354280 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA CTD PMID:29860548 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP iodixanol results in increased expression of HAVCR1 mRNA CTD PMID:19104440 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMGB1 protein CTD PMID:29860548 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP iodixanol results in increased expression of HMOX1 mRNA
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMOX1 mRNA
CTD PMID:19104440 PMID:29860548 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression EXP iodixanol results in decreased expression of NOS2 protein CTD PMID:21354280 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PINK1 protein CTD PMID:29860548 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP iodixanol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein] CTD PMID:29860548 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
iohexol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen increases expression
multiple interactions
EXP Iohexol results in increased expression of AGT protein
telmisartan inhibits the reaction [Iohexol results in increased expression of AGT protein]
CTD PMID:19452295 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Iohexol results in increased expression of BAK1 mRNA CTD PMID:29705293 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Iohexol results in increased expression of BAX mRNA CTD PMID:29705293 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Iohexol results in increased expression of BBC3 mRNA CTD PMID:29705293 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]]; Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]; Telmisartan inhibits the reaction [Iohexol results in increased activity of CASP3 protein] CTD PMID:19452295 PMID:26562095 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases expression ISO Iohexol results in increased expression of CASP9 mRNA; Iohexol results in increased expression of CASP9 protein CTD PMID:29705293 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Eng endoglin decreases expression