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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dimethyl sulfoxide
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Accession:CHEBI:28262 term browser browse the term
Definition:A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Synonyms:exact_synonym: (methanesulfinyl)methane
 related_synonym: (CH3)2SO;   Dimethylsulfoxid;   Formula=C2H6OS;   InChI=1S/C2H6OS/c1-4(2)3/h1-2H3;   InChIKey=IAZDPXIOMUYVGZ-UHFFFAOYSA-N;   S(O)Me2;   SMILES=CS(C)=O;   dimethyl sulfur oxide;   dimethyl sulphoxide;   dimethyli sulfoxidum;   dimethylsulfoxyde;   dimetil sulfoxido;   dmso;   methylsulfinylmethane;   sulfinylbis(methane)
 alt_id: CHEBI:23801;   CHEBI:42138;   CHEBI:4612
 xref: Beilstein:506008;   CAS:67-68-5;   DrugBank:DB01093;   Drug_Central:906;   Gmelin:1556;   HMDB:HMDB0002151;   KEGG:C11143;   KEGG:D01043;   LINCS:LSM-36361
 xref_mesh: MESH:D004121
 xref: PDBeChem:DMS;   PMID:11162043;   PMID:11350866;   PMID:15237653;   PMID:15588915;   PMID:15868171;   PMID:16434015;   PMID:19096138;   PMID:19382398;   PMID:21426213;   PMID:22030943;   PMID:22722716;   PMID:22768202;   PMID:22814967;   Reaxys:506008;   UM-BBD_compID:c0236;   Wikipedia:Dimethyl_Sulfoxide


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dimethyl sulfoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Dimethyl Sulfoxide results in increased expression of A2M mRNA CTD PMID:12883083 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression ISO Dimethyl Sulfoxide affects the expression of ABCB1 mRNA CTD PMID:12843640 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:11682029 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of ACTC1 mRNA
Dimethyl Sulfoxide results in decreased expression of ACTC1 mRNA
CTD PMID:22105179 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Agrp agouti related neuropeptide affects expression ISO Dimethyl Sulfoxide affects the expression of AGRP mRNA CTD PMID:24834073 NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases expression
ISO Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]
Dimethyl Sulfoxide results in decreased expression of AHR mRNA
CTD PMID:16675542, PMID:22486318 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aicda activation-induced cytidine deaminase affects expression ISO Dimethyl Sulfoxide affects the expression of AICDA mRNA CTD PMID:24834073 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
affects localization
ISO Dimethyl Sulfoxide inhibits the reaction [Acetaminophen affects the localization of AIFM1 protein]
Dimethyl Sulfoxide affects the localization of AIFM1 protein
CTD PMID:20423716, PMID:22535522 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of ALAS2 mRNA CTD PMID:21296123 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Alb albumin decreases expression ISO
EXP
Dimethyl Sulfoxide results in decreased expression of ALB mRNA
Dimethyl Sulfoxide results in decreased expression of ALB mRNA; Dimethyl Sulfoxide results in decreased expression of ALB protein
CTD PMID:14757319, PMID:22105179 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Dimethyl Sulfoxide results in increased expression of ALDH1A1 mRNA CTD PMID:22193206 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of ALOX5 protein] CTD PMID:23751068 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Apoa1 apolipoprotein A1 increases expression
increases activity
ISO
EXP
Dimethyl Sulfoxide results in increased expression of APOA1 mRNA; Dimethyl Sulfoxide results in increased expression of APOA1 protein
Dimethyl Sulfoxide results in increased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apom apolipoprotein M affects expression ISO Dimethyl Sulfoxide affects the expression of APOM mRNA CTD PMID:24834073 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G Aqp1 aquaporin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of AQP1 mRNA CTD PMID:22193206 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Ar androgen receptor multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Androgens results in increased activity of AR protein] CTD PMID:28377212 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 affects expression ISO Dimethyl Sulfoxide affects the expression of ARPC4 mRNA CTD PMID:24834073 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATF3 mRNA CTD PMID:22193206 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATP1A2 mRNA CTD PMID:22193206 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATP1B1 mRNA CTD PMID:22193206 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of ATP1B3 mRNA CTD PMID:22193206 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atp5mf ATP synthase membrane subunit f affects expression ISO Dimethyl Sulfoxide affects the expression of ATP5MF mRNA CTD PMID:24834073 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Aurkaip1 aurora kinase A interacting protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of AURKAIP1 mRNA CTD PMID:24834073 NCBI chr 5:173,274,433...173,276,170
Ensembl chr 5:173,256,637...173,276,169
JBrowse link
G Barhl2 BarH-like homeobox 2 affects expression ISO Dimethyl Sulfoxide affects the expression of BARHL2 mRNA CTD PMID:24834073 NCBI chr14:4,362,717...4,367,614
Ensembl chr14:4,362,717...4,367,605
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of BAX mRNA
Quercetin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of BAX mRNA]
CTD PMID:17652743 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bend6 BEN domain containing 6 affects expression ISO Dimethyl Sulfoxide affects the expression of BEND6 mRNA CTD PMID:24834073 NCBI chr 9:38,297,253...38,351,312
Ensembl chr 9:38,297,322...38,351,024
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of BTG2 mRNA CTD PMID:22193206 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [AHR protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ARNT protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter]; Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of CADM1 mRNA CTD PMID:22193206 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
EXP
ISO
Dimethyl Sulfoxide results in decreased cleavage of and results in decreased activity of CASP3 protein
Dimethyl Sulfoxide results in increased cleavage of CASP3 protein
CTD PMID:12370186, PMID:22535522 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA] CTD PMID:9169468 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases secretion
decreases expression
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Dimethyl Sulfoxide results in increased secretion of CCL2 protein]
Dimethyl Sulfoxide results in decreased expression of CCL2 mRNA
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of CCL2 mRNA]
CTD PMID:10925121, PMID:14576080, PMID:15689417, PMID:17529908, PMID:21878375, PMID:26860701 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl28 C-C motif chemokine ligand 28 affects expression ISO Dimethyl Sulfoxide affects the expression of CCL28 mRNA CTD PMID:24834073 NCBI chr 2:52,379,341...52,403,979
Ensembl chr 2:52,379,341...52,404,246
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein] CTD PMID:21878375 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd14 CD14 molecule increases expression ISO Dimethyl Sulfoxide results in increased expression of CD14 protein CTD PMID:26036281 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]] CTD PMID:15964820 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd3g CD3g molecule affects expression ISO Dimethyl Sulfoxide affects the expression of CD3G mRNA CTD PMID:24834073 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cd59 CD59 molecule multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased mutagenesis of CD59 gene] CTD PMID:12361925, PMID:15033018 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO Dimethyl Sulfoxide results in decreased expression of CDC25B mRNA CTD PMID:21296123 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdh1 cadherin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of CDH1 mRNA CTD PMID:22193206 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Ceacam19 CEA cell adhesion molecule 19 affects expression ISO Dimethyl Sulfoxide affects the expression of CEACAM19 mRNA CTD PMID:24834073 NCBI chr 1:80,800,951...80,809,769
Ensembl chr 1:80,800,951...80,809,769
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Dimethyl Sulfoxide results in increased expression of CEBPB mRNA CTD PMID:22193206 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cfap300 cilia and flagella associated protein 300 affects expression ISO Dimethyl Sulfoxide affects the expression of CFAP300 mRNA CTD PMID:24834073 NCBI chr 8:6,218,391...6,236,438
Ensembl chr 8:6,218,393...6,235,967
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Dimethyl Sulfoxide affects the expression of CFLAR mRNA CTD PMID:24834073 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CGREF1 mRNA CTD PMID:24834073 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Chek2 checkpoint kinase 2 affects expression ISO Dimethyl Sulfoxide affects the expression of CHEK2 mRNA CTD PMID:24834073 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cklf chemokine-like factor affects expression ISO Dimethyl Sulfoxide affects the expression of CKLF mRNA CTD PMID:24834073 NCBI chr19:903,609...914,880
Ensembl chr19:906,411...914,880
JBrowse link
G Cldn6 claudin 6 multiple interactions
decreases methylation
increases expression
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN6 mRNA]
Dimethyl Sulfoxide results in decreased methylation of CLDN6 promoter
Dimethyl Sulfoxide results in increased expression of CLDN6 mRNA
CTD PMID:18661270 NCBI chr10:12,999,256...13,002,860
Ensembl chr10:13,000,090...13,002,862
JBrowse link
G Cldn8 claudin 8 increases expression ISO Dimethyl Sulfoxide results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
JBrowse link
G Cldn9 claudin 9 multiple interactions
increases expression
decreases methylation
ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in decreased expression of CLDN9 mRNA]
Dimethyl Sulfoxide results in increased expression of CLDN9 mRNA
Dimethyl Sulfoxide results in decreased methylation of CLDN9 promoter
CTD PMID:18661270 NCBI chr10:13,003,010...13,004,441
Ensembl chr10:13,003,011...13,004,441
JBrowse link
G Cntf ciliary neurotrophic factor affects expression ISO Dimethyl Sulfoxide affects the expression of CNTF mRNA CTD PMID:24834073 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL11A1 mRNA CTD PMID:22193206 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein] CTD PMID:11682029 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL4A1 mRNA CTD PMID:22193206 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col4a5 collagen type IV alpha 5 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL4A5 mRNA CTD PMID:22193206 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression EXP Dimethyl Sulfoxide results in increased expression of COL5A1 mRNA CTD PMID:22193206 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO Dimethyl Sulfoxide results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cp ceruloplasmin increases expression EXP Dimethyl Sulfoxide results in increased expression of CP mRNA CTD PMID:22193206 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpm carboxypeptidase M increases expression EXP Dimethyl Sulfoxide results in increased expression of CPM mRNA CTD PMID:22193206 NCBI chr 7:60,654,350...60,714,620
Ensembl chr 7:60,654,350...60,714,620
JBrowse link
G Cs citrate synthase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csf1r colony stimulating factor 1 receptor increases expression ISO Dimethyl Sulfoxide results in increased expression of CSF1R mRNA CTD PMID:8445950 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cth cystathionine gamma-lyase affects expression ISO Dimethyl Sulfoxide affects the expression of CTH mRNA CTD PMID:24834073 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of CTNNB1 protein CTD PMID:20091315 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cuta cutA divalent cation tolerance homolog affects expression ISO Dimethyl Sulfoxide affects the expression of CUTA mRNA CTD PMID:24834073 NCBI chr20:5,532,024...5,533,640
Ensembl chr20:5,532,024...5,533,620
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 affects expression ISO Dimethyl Sulfoxide affects the expression of CXCL14 mRNA CTD PMID:24834073 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxxc4 CXXC finger protein 4 affects expression ISO Dimethyl Sulfoxide affects the expression of CXXC4 mRNA CTD PMID:24834073 NCBI chr 2:239,414,882...239,439,640
Ensembl chr 2:239,415,046...239,439,568
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [adrenocorticotropin zinc results in decreased expression of CYP11B2 mRNA]; Dimethyl Sulfoxide promotes the reaction [adrenocorticotropin zinc results in decreased activity of CYP11B2 protein] CTD PMID:10822027 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of CYP1A1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1A1 mRNA
Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:12147272, PMID:12843640, PMID:22486318 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
increases expression
multiple interactions
ISO Dimethyl Sulfoxide affects the expression of CYP1A2 mRNA
Dimethyl Sulfoxide results in increased expression of CYP1A2 mRNA
[hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2
CTD PMID:12843640, PMID:18347083, PMID:30262279 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA CTD PMID:12843640 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CYP27A1 mRNA]] CTD PMID:15964820 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP
ISO
Dimethyl Sulfoxide inhibits the reaction [CYP2B1 protein results in increased metabolism of 7-benzyloxy-4-trifluoromethylcoumarin]
[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]
CTD PMID:19858067, PMID:20371638 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of CYP2B6 mRNA CTD PMID:30262279 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2C11 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA; [Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2C6V1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin] CTD PMID:19858067 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP2D2 protein results in increased metabolism of 3-(2-(N,N-diethyl-N-methylammonium)ethyl)-7-methoxy-4-methylcoumarin] CTD PMID:19858067 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]] CTD PMID:11368792 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
increases expression
increases activity
multiple interactions
ISO
EXP
Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA
Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide results in increased activity of CYP2E1 protein
Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]
Dimethyl Sulfoxide results in increased expression of CYP2E1 mRNA; Dimethyl Sulfoxide results in increased expression of CYP2E1 protein
Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]
CTD PMID:1538706, PMID:3113478, PMID:3337723, PMID:8074729, PMID:9143349, PMID:12147272, PMID:12843640, PMID:17177172, PMID:19858067, PMID:30262279 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP3A2 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [CYP3A23-3A1 protein results in increased metabolism of 7-benzyloxyquinoline] CTD PMID:19858067 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression ISO Dimethyl Sulfoxide affects the expression of CYP3A5 mRNA CTD PMID:12843640 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP DMSO increases expression of Cyp7a1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cysrt1 cysteine rich tail 1 affects expression ISO Dimethyl Sulfoxide affects the expression of CYSRT1 mRNA CTD PMID:24834073 NCBI chr 3:2,458,295...2,462,037
Ensembl chr 3:2,458,295...2,459,385
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of DDIT3 mRNA CTD PMID:22193206 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Depp1 DEPP1, autophagy regulator affects expression ISO Dimethyl Sulfoxide affects the expression of DEPP1 mRNA CTD PMID:24834073 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases cleavage ISO Dimethyl Sulfoxide results in increased cleavage of DFFA protein CTD PMID:22535522 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dmap1 DNA methyltransferase 1-associated protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of DMAP1 mRNA CTD PMID:24834073 NCBI chr 5:136,533,791...136,541,795
Ensembl chr 5:136,533,792...136,541,795
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression EXP Dimethyl Sulfoxide results in increased expression of DNAJB5 mRNA CTD PMID:22193206 NCBI chr 5:58,393,197...58,402,162
Ensembl chr 5:58,393,233...58,401,870
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP Dimethyl Sulfoxide results in increased expression of DNAJB9 mRNA CTD PMID:22193206 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of DNMT1 protein CTD PMID:17065238 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of DUSP1 mRNA CTD PMID:22193206 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Eaf2 ELL associated factor 2 affects expression ISO Dimethyl Sulfoxide affects the expression of EAF2 mRNA CTD PMID:24834073 NCBI chr11:66,878,658...66,923,092
Ensembl chr11:66,878,658...66,923,092
JBrowse link
G Edn2 endothelin 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of EDN2 mRNA CTD PMID:15619356 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein CTD PMID:20561571 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter promotes the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; pyrazolanthrone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; wedelolactone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]
Dimethyl Sulfoxide results in increased expression of EDNRB mRNA; Dimethyl Sulfoxide results in increased expression of EDNRB protein
CTD PMID:20561571 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1akmt1 EEF1A lysine methyltransferase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of EEF1AKMT1 mRNA CTD PMID:24834073 NCBI chr15:37,813,115...37,830,932
Ensembl chr15:37,813,115...37,831,031
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of EFEMP1 mRNA CTD PMID:22193206 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Egr1 early growth response 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of EGR1 mRNA CTD PMID:22193206 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 increases expression ISO Dimethyl Sulfoxide results in increased expression of EIF4G2 protein CTD PMID:18491231 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of EMP1 mRNA CTD PMID:22193206 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Endog endonuclease G affects localization ISO Dimethyl Sulfoxide affects the localization of ENDOG protein CTD PMID:22535522 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of ENPP2 protein CTD PMID:22952646 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Eppin epididymal peptidase inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of EPPIN mRNA CTD PMID:24834073 NCBI chr 3:161,043,761...161,050,550
Ensembl chr 3:161,041,727...161,050,557
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [ESR1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Eva1b eva-1 homolog B affects expression ISO Dimethyl Sulfoxide affects the expression of EVA1B mRNA CTD PMID:24834073 NCBI chr 5:144,160,026...144,161,421
Ensembl chr 5:144,160,108...144,161,410
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Dimethyl Sulfoxide results in increased expression of FAS protein CTD PMID:15998540 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand decreases expression EXP Dimethyl Sulfoxide results in decreased expression of FASLG mRNA CTD PMID:10925121 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxl21 F-box and leucine-rich repeat protein 21 affects expression ISO Dimethyl Sulfoxide affects the expression of FBXL21P mRNA CTD PMID:24834073 NCBI chr17:8,505,771...8,520,208
Ensembl chr17:8,505,996...8,520,147
JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP Dimethyl Sulfoxide results in increased expression of FGG mRNA; Dimethyl Sulfoxide results in increased expression of FGG protein CTD PMID:14757319 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Flnc filamin C increases expression EXP Dimethyl Sulfoxide results in increased expression of FLNC mRNA CTD PMID:22193206 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Dimethyl Sulfoxide results in increased expression of FOS mRNA CTD PMID:22193206 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of FOXA2 mRNA CTD PMID:22105179 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression ISO Dimethyl Sulfoxide affects the expression of FRS3 mRNA CTD PMID:24834073 NCBI chr 9:15,297,794...15,306,850
Ensembl chr 9:15,297,895...15,306,465
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of GAD1 mRNA CTD PMID:17065238 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO Dimethyl Sulfoxide affects the expression of GADD45A mRNA CTD PMID:24834073 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP Dimethyl Sulfoxide results in increased expression of GADD45G mRNA CTD PMID:22193206 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression ISO Dimethyl Sulfoxide affects the expression of GAPDH mRNA CTD PMID:12843640 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gata4 GATA binding protein 4 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of GATA4 mRNA
Dimethyl Sulfoxide results in increased expression of GATA4 mRNA
CTD PMID:22105179 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of GATA6 mRNA CTD PMID:22105179 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of GJA1 mRNA CTD PMID:22193206 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of GJB1 mRNA CTD PMID:8631141 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of GJB2 mRNA CTD PMID:8631141 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GLT8D1 mRNA CTD PMID:24834073 NCBI chr16:7,082,450...7,097,405
Ensembl chr16:7,082,450...7,097,401
JBrowse link
G Gng3 G protein subunit gamma 3 affects expression ISO Dimethyl Sulfoxide affects the expression of GNG3 mRNA CTD PMID:24834073 NCBI chr 1:225,033,921...225,035,687
Ensembl chr 1:225,033,921...225,035,687
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 decreases expression EXP DMSO decreases expression of Gpbar1 protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 9:81,555,914...81,560,931
Ensembl chr 9:81,559,605...81,560,594
JBrowse link
G Gpr75 G protein-coupled receptor 75 affects expression ISO Dimethyl Sulfoxide affects the expression of GPR75 mRNA CTD PMID:24834073 NCBI chr14:115,270,452...115,278,510
Ensembl chr14:115,275,894...115,278,503
JBrowse link
G Grn granulin precursor increases expression ISO Dimethyl Sulfoxide results in increased expression of GRN mRNA CTD PMID:16873554 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTA1 protein] CTD PMID:12370186 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 affects expression ISO Dimethyl Sulfoxide affects the expression of GSTK1 mRNA CTD PMID:24834073 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein] CTD PMID:12370186 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of GSTM2 mRNA CTD PMID:22193206 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G H3f4 H3.4 histone multiple interactions
decreases methylation
ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased acetylation of H3-4 protein]
Dimethyl Sulfoxide results in decreased methylation of H3-4 protein
CTD PMID:15964820 NCBI chr10:45,304,696...45,305,106 JBrowse link
G H4f3 H1.3 linker histone, cluster member affects expression ISO Dimethyl Sulfoxide affects the expression of H1-3 mRNA CTD PMID:24834073 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 decreases expression
increases expression
ISO Dimethyl Sulfoxide results in decreased expression of HAND1 mRNA
Dimethyl Sulfoxide results in increased expression of HAND1 mRNA
CTD PMID:22105179 NCBI chr10:43,250,729...43,253,296
Ensembl chr10:43,250,745...43,253,296
JBrowse link
G Hbb hemoglobin subunit beta increases expression ISO Dimethyl Sulfoxide results in increased expression of HBB mRNA CTD PMID:21296123 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hcar1 hydroxycarboxylic acid receptor 1 affects expression ISO Dimethyl Sulfoxide affects the expression of HCAR1 mRNA CTD PMID:24834073 NCBI chr12:38,145,177...38,146,232
Ensembl chr12:38,144,855...38,146,271
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of HEXIM1 mRNA; Dimethyl Sulfoxide results in increased expression of HEXIM1 protein CTD PMID:16222702 NCBI chr10:91,200,874...91,202,986
Ensembl chr10:91,200,874...91,202,984
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression EXP Dimethyl Sulfoxide results in increased expression of HIF1A mRNA CTD PMID:22193206 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2bo histone cluster 1 H2B family member o affects expression ISO Dimethyl Sulfoxide affects the expression of H2BC17 mRNA CTD PMID:24834073 NCBI chr17:44,756,557...44,758,170
Ensembl chr17:44,756,555...44,793,927
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide results in decreased expression of HMOX1 protein
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]
Dimethyl Sulfoxide results in increased expression of HMOX1 mRNA
CTD PMID:15689417, PMID:22118543, PMID:22193206, PMID:26497626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hp haptoglobin increases expression EXP Dimethyl Sulfoxide results in increased expression of HP mRNA; Dimethyl Sulfoxide results in increased expression of HP protein CTD PMID:14757319 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression EXP Dimethyl Sulfoxide results in decreased expression of HPRT1 mRNA CTD PMID:12883083 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase affects expression ISO Dimethyl Sulfoxide affects the expression of HRAS mRNA CTD PMID:24834073 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP Dimethyl Sulfoxide results in increased expression of HSPA1A mRNA CTD PMID:22193206 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein] CTD PMID:18539414 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ier2 immediate early response 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of IER2 mRNA CTD PMID:22193206 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein] CTD PMID:21878375, PMID:29594315 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA] CTD PMID:21878375 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Ift81 intraflagellar transport 81 affects expression ISO Dimethyl Sulfoxide affects the expression of IFT81 mRNA CTD PMID:24834073 NCBI chr12:39,420,161...39,507,412
Ensembl chr12:39,423,596...39,506,890
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA] CTD PMID:21878375 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IFNGR1 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1A mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL1B mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of CCL2 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased expression of IL1B mRNA
CTD PMID:21878375, PMID:29594315 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of IL1R1 mRNA CTD PMID:21878375 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23a interleukin 23 subunit alpha affects expression ISO Dimethyl Sulfoxide affects the expression of IL23A mRNA CTD PMID:24834073 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL4 mRNA] CTD PMID:23751068 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of IL5 mRNA] CTD PMID:23751068 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of IL6 mRNA]; Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
Dimethyl Sulfoxide results in decreased secretion of IL6 protein
Dimethyl Sulfoxide inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA]
CTD PMID:9378980, PMID:10022265, PMID:15689417, PMID:21878375, PMID:24296301 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irgm immunity-related GTPase M affects expression ISO Dimethyl Sulfoxide affects the expression of IRGM mRNA CTD PMID:24834073 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO Dimethyl Sulfoxide affects the expression of ISG15 mRNA CTD PMID:24834073 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
ISO [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of ITGAM protein; Dexamethasone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of ITGAM protein]; Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAM protein] CTD PMID:7909661, PMID:15964820, PMID:16617325, PMID:22118543, PMID:26330309 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgax integrin subunit alpha X multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAX protein] CTD PMID:15964820 NCBI chr 1:199,555,560...199,576,948
Ensembl chr 1:199,555,722...199,576,932
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGB2 protein] CTD PMID:15964820 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Dimethyl Sulfoxide results in increased expression of JUN mRNA
Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of JUN mRNA]
CTD PMID:7662713, PMID:22193206 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of KLF2 mRNA CTD PMID:22193206 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf4 Kruppel like factor 4 increases expression EXP Dimethyl Sulfoxide results in increased expression of KLF4 mRNA CTD PMID:22193206 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klhl41 kelch-like family member 41 affects expression ISO Dimethyl Sulfoxide affects the expression of KLHL41 mRNA CTD PMID:24834073 NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
JBrowse link
G Krt15 keratin 15 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of KRT15 mRNA CTD PMID:22105179 NCBI chr10:88,046,803...88,050,622
Ensembl chr10:88,046,803...88,050,622
JBrowse link
G Lama1 laminin subunit alpha 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of LAMA1 mRNA CTD PMID:22193206 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Lamb2 laminin subunit beta 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of LAMB2 mRNA CTD PMID:22193206 NCBI chr 8:117,268,335...117,280,517
Ensembl chr 8:117,268,337...117,280,517
JBrowse link
G Ldhc lactate dehydrogenase C affects expression ISO Dimethyl Sulfoxide affects the expression of LDHC mRNA CTD PMID:24834073 NCBI chr 1:102,914,875...102,931,843
Ensembl chr 1:102,915,191...102,931,839
JBrowse link
G Lgals1 galectin 1 affects expression ISO Dimethyl Sulfoxide affects the expression of LGALS1 mRNA CTD PMID:24834073 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Llgl2 LLGL scribble cell polarity complex component 2 affects expression ISO Dimethyl Sulfoxide affects the expression of LLGL2 mRNA CTD PMID:24834073 NCBI chr10:104,367,826...104,403,726
Ensembl chr10:104,368,247...104,403,724
JBrowse link
G LOC103690190 histone H2A type 1-E affects expression ISO Dimethyl Sulfoxide affects the expression of H2AC6 mRNA CTD PMID:24834073 NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Lrrc4 leucine rich repeat containing 4 affects expression ISO Dimethyl Sulfoxide affects the expression of LRRC4 mRNA CTD PMID:24834073 NCBI chr 4:56,110,658...56,114,254
Ensembl chr 4:56,110,658...56,114,254
JBrowse link
G Ltc4s leukotriene C4 synthase multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of LTC4S mRNA] CTD PMID:23751068 NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625
JBrowse link
G Lyrm9 LYR motif containing 9 affects expression ISO Dimethyl Sulfoxide affects the expression of LYRM9 mRNA CTD PMID:24834073 NCBI chr10:66,099,478...66,113,559
Ensembl chr10:66,099,531...66,113,559
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression
multiple interactions
ISO Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K1 mRNA]
CTD PMID:31265865 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
increases expression
ISO cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAP2K2 mRNA] CTD PMID:31265865 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
decreases activity
EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased activity of MAP3K5 protein]
Dimethyl Sulfoxide results in decreased activity of MAP3K5 protein
CTD PMID:12370186 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects expression
multiple interactions
increases expression
ISO Dimethyl Sulfoxide affects the expression of MAPK3 mRNA
cucurbitacin IIa inhibits the reaction [Dimethyl Sulfoxide results in increased expression of MAPK3 mRNA]
CTD PMID:24834073, PMID:31265865 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mat1a methionine adenosyltransferase 1A increases activity ISO Dimethyl Sulfoxide results in increased activity of MAT1A protein CTD PMID:8373829 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Mat2a methionine adenosyltransferase 2A increases activity ISO Dimethyl Sulfoxide results in increased activity of MAT2A protein CTD PMID:8373829 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mc1r melanocortin 1 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of MC1R mRNA CTD PMID:24834073 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression
decreases expression
ISO Dimethyl Sulfoxide results in increased expression of MEF2C mRNA
Dimethyl Sulfoxide results in decreased expression of MEF2C mRNA
CTD PMID:22105179 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mettl26 methyltransferase like 26 affects expression ISO Dimethyl Sulfoxide affects the expression of METTL26 mRNA CTD PMID:24834073 NCBI chr10:15,239,753...15,255,054
Ensembl chr10:15,241,590...15,252,413
JBrowse link
G Mfap5 microfibril associated protein 5 affects expression ISO Dimethyl Sulfoxide affects the expression of MFAP5 mRNA CTD PMID:24834073 NCBI chr 4:155,313,671...155,336,228
Ensembl chr 4:155,313,671...155,336,228
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of MMP1 mRNA; Dimethyl Sulfoxide results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
EXP [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]
Dimethyl Sulfoxide results in increased expression of MMP2 protein
CTD PMID:26497626 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Dimethyl Sulfoxide inhibits the reaction [Ethanol results in increased activity of MMP9 protein]
Dimethyl Sulfoxide results in increased expression of MMP9 protein
CTD PMID:17603938, PMID:26497626 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase increases secretion ISO Dimethyl Sulfoxide results in increased secretion of MPO protein CTD PMID:21633126 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrpl43 mitochondrial ribosomal protein L43 affects expression ISO Dimethyl Sulfoxide affects the expression of MRPL43 mRNA CTD PMID:24834073 NCBI chr 1:264,755,537...264,756,404
Ensembl chr 1:264,755,538...264,756,546
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein] CTD PMID:10640773 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of PZP mRNA; Dimethyl Sulfoxide results in increased expression of PZP protein CTD PMID:14757319 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Mxra8 matrix remodeling associated 8 increases expression EXP Dimethyl Sulfoxide results in increased expression of MXRA8 mRNA CTD PMID:22193206 NCBI chr 5:173,288,200...173,292,926
Ensembl chr 5:173,288,447...173,292,929
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Dimethyl Sulfoxide results in decreased expression of MYC mRNA CTD PMID:7798212 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myo1g myosin IG increases expression EXP Dimethyl Sulfoxide results in increased expression of MYO1G mRNA CTD PMID:22193206 NCBI chr14:86,781,243...86,796,393
Ensembl chr14:86,781,202...86,796,378
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NANOG mRNA CTD PMID:22105179 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Nefh neurofilament heavy decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NEFH mRNA CTD PMID:22105179 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nes nestin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NES mRNA CTD PMID:22105179 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
decreases expression
EXP [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]
Dimethyl Sulfoxide results in decreased expression of NFE2L2 protein
CTD PMID:26497626 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKB2 mRNA] CTD PMID:21878375 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of NFKBIA mRNA] CTD PMID:21878375 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nmi N-myc (and STAT) interactor affects expression ISO Dimethyl Sulfoxide affects the expression of NMI mRNA CTD PMID:24834073 NCBI chr 3:37,458,891...37,480,984
Ensembl chr 3:37,458,890...37,480,984
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NMRK1 mRNA CTD PMID:24834073 NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of NOS2 mRNA CTD PMID:21878375 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch3 notch receptor 3 increases expression ISO Dimethyl Sulfoxide results in increased expression of NOTCH3 mRNA CTD PMID:20713136 NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of NQO1 mRNA CTD PMID:22193206 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP DMSO decreases expression of Nr1h4 mRNA and protein in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2B10 protein]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 mRNA]; NR1I3 gene mutant form inhibits the reaction [[Phenobarbital co-treated with Dimethyl Sulfoxide] results in increased expression of CYP2C55 protein] CTD PMID:20371638 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nudt1 nudix hydrolase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of NUDT1 mRNA CTD PMID:24834073 NCBI chr12:16,391,578...16,398,771
Ensembl chr12:16,391,578...16,395,029
JBrowse link
G Ocln occludin increases expression ISO Dimethyl Sulfoxide results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of ORM1 mRNA; Dimethyl Sulfoxide results in increased expression of ORM1 protein CTD PMID:14757319 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Ostn osteocrin affects expression ISO Dimethyl Sulfoxide affects the expression of OSTN mRNA CTD PMID:24834073 NCBI chr11:76,851,923...76,888,140
Ensembl chr11:76,851,322...76,888,178
JBrowse link
G Padi4 peptidyl arginine deiminase 4 multiple interactions
increases expression
ISO Calcimycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of PADI4 protein]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of PADI4 mRNA] CTD PMID:15964820, PMID:29425503 NCBI chr 5:159,260,675...159,293,906
Ensembl chr 5:159,260,675...159,293,673
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha affects expression ISO Dimethyl Sulfoxide affects the expression of PARD6A mRNA CTD PMID:24834073 NCBI chr19:37,668,133...37,670,450
Ensembl chr19:37,668,133...37,672,729
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Dimethyl Sulfoxide results in increased cleavage of PARP1 protein CTD PMID:22535522 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Dimethyl Sulfoxide results in increased expression of PDCD4 protein CTD PMID:17259349 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Phf6 PHD finger protein 6 affects expression ISO Dimethyl Sulfoxide affects the expression of PHF6 mRNA CTD PMID:24834073 NCBI chr  X:158,698,353...158,739,855
Ensembl chr  X:158,698,356...158,739,838
Ensembl chr  X:158,698,356...158,739,838
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing affects expression ISO Dimethyl Sulfoxide affects the expression of PIKFYVE mRNA CTD PMID:24834073 NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838
JBrowse link
G Pjvk pejvakin affects expression ISO Dimethyl Sulfoxide affects the expression of PJVK mRNA CTD PMID:24834073 NCBI chr 3:63,508,386...63,518,163
Ensembl chr 3:63,510,293...63,518,147
JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PLA2G2A mRNA CTD PMID:21878375 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PLEKHF1 mRNA CTD PMID:24834073 NCBI chr 1:94,609,041...94,616,565
Ensembl chr 1:94,609,377...94,610,854
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of PLOD2 mRNA CTD PMID:22193206 NCBI chr 8:99,977,334...100,059,736
Ensembl chr 8:99,977,334...100,059,736
JBrowse link
G Pomc proopiomelanocortin decreases expression ISO Dimethyl Sulfoxide results in decreased expression of POMC protein CTD PMID:15680486 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
decreases activity
ISO Dimethyl Sulfoxide inhibits the reaction [[POR protein results in increased metabolism of Diquat] which results in increased abundance of Hydroxyl Radical]
Dimethyl Sulfoxide results in decreased activity of POR protein
Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]; Dimethyl Sulfoxide promotes the reaction [Hemin inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Dimethyl Sulfoxide promotes the reaction [Hemin results in decreased activity of POR protein]; Hemin promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [POR protein results in decreased expression of CYP2D6 protein]]; Hemin promotes the reaction [Dimethyl Sulfoxide results in decreased activity of POR protein]
CTD PMID:11368792, PMID:21215309 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pot1 protection of telomeres 1 multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA]; [Dimethyl Sulfoxide co-treated with Tretinoin] results in increased expression of POT1 mRNA CTD PMID:26330309 NCBI chr 4:51,888,632...51,946,764
Ensembl chr 4:51,888,634...51,946,715
JBrowse link
G Pou5f1 POU class 5 homeobox 1 affects expression ISO Dimethyl Sulfoxide affects the expression of POU5F1 mRNA CTD PMID:24834073 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARA mRNA CTD PMID:21878375 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PPARG mRNA CTD PMID:21878375 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Pqbp1 polyglutamine binding protein 1 affects expression ISO Dimethyl Sulfoxide affects the expression of PQBP1 mRNA CTD PMID:24834073 NCBI chr  X:15,448,570...15,453,130
Ensembl chr  X:15,348,138...15,453,130
JBrowse link
G Prmt1 protein arginine methyltransferase 1 multiple interactions ISO PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]] CTD PMID:31877331 NCBI chr 1:100,971,132...100,980,411
Ensembl chr 1:100,971,273...100,980,340
JBrowse link
G Prph peripherin affects expression ISO Dimethyl Sulfoxide affects the expression of PRPH mRNA CTD PMID:24834073 NCBI chr 7:140,742,406...140,746,197
Ensembl chr 7:140,742,418...140,746,197
JBrowse link
G Ptgds prostaglandin D2 synthase multiple interactions ISO [OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGDS mRNA] CTD PMID:23751068 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of PTGS1 mRNA CTD PMID:21878375 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
[Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Dimethyl Sulfoxide results in increased expression of PTGS2 protein
[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein; resveratrol inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein]; Triamcinolone Acetonide inhibits the reaction [[OVAL protein co-treated with enterotoxin B, staphylococcal co-treated with Dimethyl Sulfoxide] results in increased expression of PTGS2 protein]
CTD PMID:21878375, PMID:23751068, PMID:26497626 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pxdn peroxidasin increases expression EXP Dimethyl Sulfoxide results in increased expression of PXDN mRNA CTD PMID:22193206 NCBI chr 6:48,866,496...48,982,368
Ensembl chr 6:48,866,601...48,980,340
JBrowse link
G Rab3c RAB3C, member RAS oncogene family affects expression ISO Dimethyl Sulfoxide affects the expression of RAB3C mRNA CTD PMID:24834073 NCBI chr 2:41,570,955...41,786,681
Ensembl chr 2:41,570,597...41,785,792
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of RAF1 mRNA CTD PMID:31265865 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Reln reelin increases expression ISO Dimethyl Sulfoxide results in increased expression of RELN mRNA CTD PMID:17065238 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Rfx3 regulatory factor X3 affects expression ISO Dimethyl Sulfoxide affects the expression of RFX3 mRNA CTD PMID:24834073 NCBI chr 1:245,853,332...246,110,648
Ensembl chr 1:245,859,633...246,110,218
JBrowse link
G RGD1309036 hypothetical LOC292874 affects expression ISO Dimethyl Sulfoxide affects the expression of C19ORF81 mRNA CTD PMID:24834073 NCBI chr 1:100,346,096...100,361,340
Ensembl chr 1:100,346,096...100,359,511
JBrowse link
G RGD1309540 similar to hypothetical protein MGC40841; similar to hypothetical protein MGC4707 affects expression ISO Dimethyl Sulfoxide affects the expression of C11ORF49 mRNA CTD PMID:24834073 NCBI chr 3:80,092,589...80,349,249
Ensembl chr 3:80,095,042...80,349,145
JBrowse link
G RGD1309651 similar to 1190005I06Rik protein affects expression ISO Dimethyl Sulfoxide affects the expression of C16ORF74 mRNA CTD PMID:24834073 NCBI chr19:54,184,554...54,210,872
Ensembl chr19:54,184,946...54,210,515
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression ISO Dimethyl Sulfoxide affects the expression of RNASE4 mRNA CTD PMID:24834073 NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389
Ensembl chr15:28,018,040...28,035,389
JBrowse link
G Rnf152 ring finger protein 152 affects expression ISO Dimethyl Sulfoxide affects the expression of RNF152 mRNA CTD PMID:24834073 NCBI chr13:25,183,295...25,262,785
Ensembl chr13:25,186,106...25,262,469
JBrowse link
G RT1-Da RT1 class II, locus Da decreases expression ISO Dimethyl Sulfoxide results in decreased expression of HLA-DRA mRNA CTD PMID:21878375 NCBI chr20:4,127,644...4,132,616
Ensembl chr20:4,127,644...4,132,616
JBrowse link
G Rxra retinoid X receptor alpha increases expression
affects response to substance
ISO Dimethyl Sulfoxide results in increased expression of RXRA mRNA; Dimethyl Sulfoxide results in increased expression of RXRA protein
RXRA protein affects the susceptibility to Dimethyl Sulfoxide
CTD PMID:9751115 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression ISO Dimethyl Sulfoxide results in decreased expression of RXRG protein CTD PMID:9751115 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G S100a13 S100 calcium binding protein A13 affects expression ISO Dimethyl Sulfoxide affects the expression of S100A13 mRNA CTD PMID:24834073 NCBI chr 2:189,906,022...189,912,516
Ensembl chr 2:189,906,022...189,912,516
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A8 mRNA CTD PMID:1733233 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Dimethyl Sulfoxide results in increased expression of S100A9 mRNA CTD PMID:1733233 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Sdhaf4 succinate dehydrogenase complex assembly factor 4 affects expression ISO Dimethyl Sulfoxide affects the expression of SDHAF4 mRNA CTD PMID:24834073 NCBI chr 9:30,243,261...30,251,478
Ensembl chr 9:30,243,610...30,251,388
JBrowse link
G Selenbp1 selenium binding protein 1 increases abundance ISO SELENBP1 gene mutant form results in increased abundance of Dimethyl Sulfoxide CTD PMID:29255262 NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SERP2 mRNA CTD PMID:24834073 NCBI chr15:58,687,784...58,712,023
Ensembl chr15:58,687,786...58,711,872
JBrowse link
G Slc24a2 solute carrier family 24 member 2 increases expression EXP Dimethyl Sulfoxide results in increased expression of SLC24A2 mRNA CTD PMID:22193206 NCBI chr 5:105,336,287...105,579,959
Ensembl chr 5:105,336,262...105,582,375
JBrowse link
G Slc24a4 solute carrier family 24 member 4 increases expression EXP Dimethyl Sulfoxide results in increased expression of SLC24A4 mRNA CTD PMID:22193206 NCBI chr 6:126,015,799...126,158,727
Ensembl chr 6:126,018,841...126,153,867
JBrowse link
G Slc2a6 solute carrier family 2 member 6 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC2A6 mRNA CTD PMID:24834073 NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136
JBrowse link
G Slc35e4 solute carrier family 35, member E4 affects expression ISO Dimethyl Sulfoxide affects the expression of SLC35E4 mRNA CTD PMID:24834073 NCBI chr14:84,163,971...84,170,835
Ensembl chr14:84,163,972...84,170,835
JBrowse link
G Snx15 sorting nexin 15 affects expression ISO Dimethyl Sulfoxide affects the expression of SNX15 mRNA CTD PMID:24834073 NCBI chr 1:221,487,058...221,496,200
Ensembl chr 1:221,487,051...221,496,306
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of SOD3 mRNA CTD PMID:22193206 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sord sorbitol dehydrogenase multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Carbon Tetrachloride results in increased activity of SORD protein] CTD PMID:17177172 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression ISO Dimethyl Sulfoxide results in decreased expression of SOX17 mRNA CTD PMID:22105179 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO Dimethyl Sulfoxide promotes the reaction [SP1 protein binds to CAD promoter] CTD PMID:16675542 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SPINK2 mRNA CTD PMID:24834073 NCBI chr14:33,247,278...33,253,913
Ensembl chr14:33,247,274...33,253,913
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP DMSO increases expression of Srebf1 mRNA in rat liver; reaction inhibited by INT-767 RGD PMID:30038487 RGD:15092090 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression EXP Dimethyl Sulfoxide results in increased expression of SRXN1 mRNA CTD PMID:22193206 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 affects expression ISO Dimethyl Sulfoxide affects the expression of STAC3 mRNA CTD PMID:24834073 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [cucurbitacin IIa co-treated with Dimethyl Sulfoxide] results in increased expression of STAT3 mRNA CTD PMID:31265865 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethyl Sulfoxide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] CTD PMID:14570759 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects expression ISO Dimethyl Sulfoxide affects the expression of SUMO1 mRNA CTD PMID:24834073 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Syce2 synaptonemal complex central element protein 2 affects expression ISO Dimethyl Sulfoxide affects the expression of SYCE2 mRNA CTD PMID:24834073 NCBI chr19:25,982,003...26,002,399
Ensembl chr19:25,983,169...26,001,317
JBrowse link
G Tas2r103 taste receptor, type 2, member 103 affects expression ISO Dimethyl Sulfoxide affects the expression of TAS2R14 mRNA CTD PMID:24834073 NCBI chr 4:167,179,587...167,203,109
Ensembl chr 4:167,179,718...167,180,656
JBrowse link
G Tatdn1 TatD DNase domain containing 1 affects expression ISO Dimethyl Sulfoxide affects the expression of TATDN1 mRNA CTD PMID:24834073 NCBI chr 7:98,782,164...98,813,001
Ensembl chr 7:98,782,178...98,804,499
JBrowse link
G Terc telomerase RNA component multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERC mRNA CTD PMID:26330309 NCBI chr 2:116,432,723...116,433,110
Ensembl chr 2:116,432,691...116,433,110
JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions ISO 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; 3,4,5,3',4'-pentachlorobiphenyl affects the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF1 mRNA CTD PMID:26330309 NCBI chr 5:2,853,455...2,882,731
Ensembl chr 5:2,853,459...2,882,668
JBrowse link
G Terf2 telomeric repeat binding factor 2 multiple interactions ISO [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dimethyl Sulfoxide co-treated with Tretinoin] results in decreased expression of TERF2 mRNA; [Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of TERF2 mRNA CTD PMID:26330309 NCBI chr19:39,271,992...39,301,506
Ensembl chr19:39,272,499...39,300,893
JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
ISO Dimethyl Sulfoxide results in decreased expression of TERT mRNA
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [[Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein]; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased activity of TERT protein; [Tretinoin co-treated with Dimethyl Sulfoxide] results in decreased expression of TERT mRNA
CTD PMID:16180984, PMID:26330309 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tf transferrin increases expression EXP Dimethyl Sulfoxide results in increased expression of TF mRNA CTD PMID:22193206 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfpi tissue factor pathway inhibitor affects expression ISO Dimethyl Sulfoxide affects the expression of TFPI mRNA CTD PMID:24834073 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H3-4 protein modified form binds to TGM2 gene]; [Alitretinoin co-treated with Dimethyl Sulfoxide] promotes the reaction [H4-16 protein modified form binds to TGM2 gene]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]; Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 protein]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Alitretinoin results in increased expression of TGM2 mRNA]] CTD PMID:15964820 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] CTD PMID:11682029 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tirap TIR domain containing adaptor protein affects expression ISO Dimethyl Sulfoxide affects the expression of TIRAP mRNA CTD PMID:24834073 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Dimethyl Sulfoxide results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tmem121 transmembrane protein 121 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM121 mRNA CTD PMID:24834073 NCBI chr 6:137,994,675...138,002,897
Ensembl chr 6:137,997,335...137,998,291
JBrowse link
G Tmem134 transmembrane protein 134 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM134 mRNA CTD PMID:24834073 NCBI chr 1:219,374,005...219,383,365
Ensembl chr 1:219,374,060...219,379,557
JBrowse link
G Tmem150c transmembrane protein 150C affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM150C mRNA CTD PMID:24834073 NCBI chr14:11,094,655...11,166,323
Ensembl chr14:11,095,163...11,166,428
JBrowse link
G Tmem266 transmembrane protein 266 affects expression ISO Dimethyl Sulfoxide affects the expression of TMEM266 mRNA CTD PMID:24834073 NCBI chr 8:59,952,732...60,014,363
Ensembl chr 8:59,900,651...60,014,363
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of CCL5 protein]; Dimethyl Sulfoxide inhibits the reaction [[Lipopolysaccharides co-treated with IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [ferrous sulfate promotes the reaction [Hydrogen Peroxide results in increased secretion of TNF protein]]
Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]
CTD PMID:7539275, PMID:14576080, PMID:21878375, PMID:22319556 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP Dimethyl Sulfoxide results in increased expression of TNFRSF12A mRNA CTD PMID:22193206 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO Dimethyl Sulfoxide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] CTD PMID:9870925 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 affects expression ISO Dimethyl Sulfoxide affects the expression of TOMM5 mRNA CTD PMID:24834073 NCBI chr 5:60,655,708...60,658,568
Ensembl chr 5:60,655,379...60,658,535
JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of TPM3 mRNA CTD PMID:22193206 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Tra2b transformer 2 beta homolog increases expression EXP Dimethyl Sulfoxide results in increased expression of TRA2B mRNA CTD PMID:22193206 NCBI chr11:82,373,828...82,392,208
Ensembl chr11:82,373,870...82,392,083
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP Dimethyl Sulfoxide results in increased expression of TRIB3 mRNA CTD PMID:22193206 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 affects expression ISO Dimethyl Sulfoxide affects the expression of TSC22D3 mRNA CTD PMID:24834073 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO Dimethyl Sulfoxide results in decreased expression of TUBB3 mRNA CTD PMID:22105179 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G U2af1l4 U2 small nuclear RNA auxiliary factor 1-like 4 affects expression ISO Dimethyl Sulfoxide affects the expression of U2AF1L4 mRNA CTD PMID:24834073 NCBI chr 1:89,017,414...89,019,651
Ensembl chr 1:89,017,479...89,019,937
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C affects expression ISO Dimethyl Sulfoxide affects the expression of UBE2C mRNA CTD PMID:24834073 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ufsp1 UFM1-specific peptidase 1 affects expression ISO Dimethyl Sulfoxide affects the expression of UFSP1 mRNA CTD PMID:24834073 NCBI chr12:22,471,141...22,472,357
Ensembl chr12:22,471,391...22,472,044
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A6 mRNA CTD PMID:12843640 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects expression ISO Dimethyl Sulfoxide affects the expression of UGT1A9 mRNA CTD PMID:12843640 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Upk3b uroplakin 3B affects expression ISO Dimethyl Sulfoxide affects the expression of UPK3B mRNA CTD PMID:24834073 NCBI chr12:23,676,169...23,682,395
Ensembl chr12:23,676,152...23,682,381
JBrowse link
G Uts2r urotensin 2 receptor affects expression ISO Dimethyl Sulfoxide affects the expression of UTS2R mRNA CTD PMID:24834073 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451
JBrowse link
G Wapl WAPL cohesin release factor increases expression ISO Dimethyl Sulfoxide results in increased expression of WAPL mRNA CTD PMID:15797623 NCBI chr16:11,029,325...11,108,867
Ensembl chr16:11,032,531...11,106,589
JBrowse link
G Wnt11 Wnt family member 11 affects expression ISO Dimethyl Sulfoxide affects the expression of WNT11 mRNA CTD PMID:24834073 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Zfp36 zinc finger protein 36 affects expression ISO Dimethyl Sulfoxide affects the expression of ZFP36 mRNA CTD PMID:24834073 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      chemical role 19283
        antioxidant 14226
          radical scavenger 5207
            dimethyl sulfoxide 311
              trametinib dimethyl sulfoxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            heteroorganic entity 19175
                              organochalcogen compound 18886
                                organosulfur compound 15218
                                  sulfoxide 3721
                                    dimethyl sulfoxide 311
                                      trametinib dimethyl sulfoxide 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.