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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of protein kinase activity
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Accession:GO:0045860 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein kinase activity.
Synonyms:exact_synonym: up regulation of protein kinase activity;   upregulation of protein kinase activity
 narrow_synonym: stimulation of protein kinase activity


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positive regulation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 involved_in IDA
ISO		 PMID:23800469
(PMID:23800469)		 RGD PMID:23800469 PMID:23800469 RGD:8554519 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in IDA PMID:18256313 UniProt PMID:18256313 RGD:8553544 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 acts_upstream_of_or_within ISO (PMID:14761976) RGD PMID:14761976 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16049005)		 UniProt
RGD		 PMID:16049005 GO_REF:0000024 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737 		JBrowse link
G Axin1 axin 1 involved_in IDA
ISO		 (PMID:15526030) RGD PMID:15526030 PMID:15228590 RGD:1304344 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 IDA RGD PMID:9566905 RGD:68736 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Cacul1 CDK2-associated, cullin domain 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19829063)		 UniProt
RGD		 PMID:19829063 GO_REF:0000024 NCBI chr 1:259,666,335...259,726,249
Ensembl chr 1:259,668,516...259,726,082 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:7642608 RGD:632489 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Cartpt CART prepropeptide acts_upstream_of IDA
ISO		 PMID:15908120
(PMID:15908120)		 RGD PMID:15908120 PMID:15908120 RGD:8554672 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:14592837) RGD PMID:14592837 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) RGD PMID:20675382 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccnb1 cyclin B1 IMP histone H1 RGD PMID:15291744 RGD:1578405 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cd4 Cd4 molecule involved_in ISO (PMID:2118992) RGD PMID:2118992 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cdc25b cell division cycle 25B acts_upstream_of_or_within ISO MGI:2682953 (PMID:11912493) RGD PMID:11912493 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 acts_upstream_of_or_within ISO MGI:1861809 (PMID:16203963) RGD PMID:16203963 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 acts_upstream_of_or_within ISO MGI:1330828 (PMID:11517264) RGD PMID:11517264 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 acts_upstream_of_or_within ISO MGI:101764 (PMID:11517264) RGD PMID:11517264 NCBI chr 9:76,416,251...76,417,719
Ensembl chr 9:76,416,062...76,418,344 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (PMID:22869755) RGD PMID:22869755 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cenpe centromere protein E involved_in ISO (PMID:12925705) RGD PMID:12925705 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:97306 (PMID:17053831) RGD PMID:17053831 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Dab1 DAB adaptor protein 1 acts_upstream_of_or_within ISO MGI:103022 (PMID:12526740) RGD PMID:12526740 NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552 		JBrowse link
G Dag1 dystroglycan 1 IMP RGD PMID:18556591 RGD:11541067 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:21572393 RGD:9587767 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (PMID:20564243) RGD PMID:20564243 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Epo erythropoietin involved_in ISO (PMID:21095239) RGD PMID:21095239 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ereg epiregulin involved_in ISS
ISO		 GO_REF:0000024
(PMID:14581411)		 UniProt
RGD		 PMID:14581411 GO_REF:0000024 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Gas6 growth arrest specific 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:7854420)		 UniProt
RGD		 PMID:7854420 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gcg glucagon involved_in ISO (PMID:19915011) RGD PMID:19915011 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B acts_upstream_of_or_within ISO MGI:5293387 (PMID:23169819) RGD PMID:23169819 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 involved_in ISO (PMID:17563371) RGD PMID:17563371 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Jtb jumping translocation breakpoint involved_in ISS
ISO		 GO_REF:0000024
(PMID:21225229)		 UniProt
RGD		 PMID:21225229 GO_REF:0000024 NCBI chr 2:175,685,392...175,689,609
Ensembl chr 2:175,684,993...175,690,108 		JBrowse link
G Lat linker for activation of T cells involved_in ISO (PMID:14624253) RGD PMID:14624253 NCBI chr 1:180,936,536...180,941,561
Ensembl chr 1:180,936,534...180,941,578 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 involved_in ISO (PMID:14624253) RGD PMID:14624253 NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559 		JBrowse link
G Lrp8 LDL receptor related protein 8 acts_upstream_of_or_within ISO MGI:103022|MGI:98935 (PMID:12526740) RGD PMID:12526740 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:19302196) RGD PMID:19302196 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 involved_in ISO (PMID:11980910) RGD PMID:11980910 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in ISO (PMID:27511108) RGD PMID:27511108 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (PMID:27511108) RGD PMID:27511108 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 involved_in ISO (PMID:26323690) RGD PMID:26323690 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881 		JBrowse link
G Mmd monocyte to macrophage differentiation-associated involved_in ISO (PMID:21968647) RGD PMID:21968647 NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528 		JBrowse link
G Mmd2 monocyte to macrophage differentiation-associated 2 involved_in ISO (PMID:21968647) RGD PMID:21968647 NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773 		JBrowse link
G Mrnip MRN complex interacting protein involved_in ISO (PMID:27568553) RGD PMID:27568553 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469 		JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within ISO (PMID:17015463) RGD PMID:17015463 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Nrg1 neuregulin 1 acts_upstream_of_or_within ISO (PMID:10597237), (PMID:7816098) RGD PMID:7816098 PMID:10597237 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:9653190 RGD:8554053 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 involved_in ISO (PMID:15877279) RGD PMID:15877279 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:15192701) RGD PMID:15192701 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Ptk2 protein tyrosine kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11331870)		 UniProt
RGD		 PMID:11331870 GO_REF:0000024 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:7544443)		 UniProt
RGD		 PMID:7544443 GO_REF:0000024 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Pxn paxillin acts_upstream_of_or_within ISO (PMID:23658024) RGD PMID:23658024 NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in IMP PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in IMP
ISO
ISS		 PMID:17724123
(PMID:23800469)
(PMID:11359771), (PMID:23800469)
GO_REF:0000024		 RGD
UniProt		 PMID:11359771 PMID:23800469 PMID:17724123 GO_REF:0000024, RGD:8554481 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rassf2 Ras association domain family member 2 acts_upstream_of_or_within ISO (PMID:19962960) RGD PMID:19962960 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431 		JBrowse link
G Reln reelin involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:108554|MGI:1340044|MGI:98935 (PMID:12526740)		 UniProt
RGD		 PMID:12526740 GO_REF:0000024 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Sdc4 syndecan 4 IMP RGD PMID:12571249 RGD:1580031 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Snx9 sorting nexin 9 involved_in ISO (PMID:18388313) RGD PMID:18388313 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A involved_in ISO (PMID:28666995)
(PMID:28031483)		 RGD PMID:28031483 PMID:28666995 NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11460167)		 UniProt
RGD		 PMID:11460167 GO_REF:0000024 NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756 		JBrowse link
G Traf4 Tnf receptor associated factor 4 involved_in ISO (PMID:16157600) RGD PMID:16157600 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Vegfc vascular endothelial growth factor C involved_in ISO (PMID:26934950) RGD PMID:26934950 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vldlr very low density lipoprotein receptor acts_upstream_of_or_within ISO MGI:103022|MGI:1340044 (PMID:12526740) RGD PMID:12526740 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
G Wdr24 WD repeat domain 24 acts_upstream_of_or_within ISO (PMID:31915252) RGD PMID:31915252 NCBI chr10:14,844,089...14,848,871
Ensembl chr10:14,843,728...14,848,864 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:22504299) RGD PMID:22504299 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:22504299) RGD PMID:22504299 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ghr growth hormone receptor IDA RGD PMID:11244571 RGD:1624962 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:8378315) RGD PMID:8378315 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20304997)		 UniProt
RGD		 PMID:20304997 GO_REF:0000024 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:16393965) RGD PMID:16393965 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712 		JBrowse link
G Prl3d4 prolactin family 3, subfamily D, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667 		JBrowse link
G Prlr prolactin receptor involved_in ISO (PMID:10585417) RGD PMID:10585417 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP
ISO		 (PMID:8670418) RGD PMID:8670418 PMID:11818507 RGD:633057 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
activation of NF-kappaB-inducing kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card10 caspase recruitment domain family, member 10 involved_in ISO (PMID:11259443) RGD PMID:11259443 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224 		JBrowse link
G Chi3l1 chitinase 3 like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21546314)		 UniProt
RGD		 PMID:21546314 GO_REF:0000024 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Cops8 COP9 signalosome subunit 8 involved_in ISO (PMID:22992343) RGD PMID:22992343 NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258 		JBrowse link
G Tnfsf15 TNF superfamily member 15 acts_upstream_of_or_within ISO (PMID:11911831) RGD PMID:11911831 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Zfp91 zinc finger protein 91 involved_in ISO (PMID:20682767) RGD PMID:20682767 NCBI chr 1:209,891,344...209,928,890
Ensembl chr 1:209,891,344...209,927,762 		JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 involved_in IMP PMID:25381556 UniProt PMID:25381556 RGD:13825194 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Fbn1 fibrillin 1 involved_in ISO (PMID:27087445) RGD PMID:27087445 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity-dependent neuroprotector homeobox IDA Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:15653687) RGD PMID:15653687 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Axin1 axin 1 involved_in ISO (PMID:9601641) RGD PMID:9601641 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Cab39 calcium binding protein 39 acts_upstream_of_or_within ISO (PMID:18854309) RGD PMID:18854309 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:17983652) RGD PMID:17983652 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:16054095 RGD:2311420 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 IDA RGD PMID:16054095 RGD:2311420 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Ccdc88a coiled coil domain containing 88A involved_in ISO (PMID:21954290) RGD PMID:21954290 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Clspn claspin involved_in ISO (PMID:16885022) RGD PMID:16885022 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 acts_upstream_of_or_within ISO (PMID:17187070) RGD PMID:17187070 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12086672 RGD:1580677 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:15254234) RGD PMID:15254234 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:20841353 RGD:150540305 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO (PMID:10022831) RGD PMID:10022831 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (PMID:24784001) RGD PMID:24784001 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within ISO MGI:3759678 (PMID:16129705) RGD PMID:16129705 NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO (PMID:10713049) RGD PMID:10713049 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prnp prion protein involved_in ISO ComplexPortal:CPX-1134 (PMID:23386614) RGD PMID:23386614 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:22817896)		 UniProt
RGD		 PMID:22817896 GO_REF:0000024 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within ISO (PMID:31915252) RGD PMID:31915252 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO MGI:1857755 (PMID:8301134) RGD PMID:8301134 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Stk11 serine/threonine kinase 11 involved_in
acts_upstream_of_or_within		 ISS
ISO		 PMID:15731909
(PMID:15731909)
(PMID:18854309)		 RGD PMID:15731909 PMID:18854309 PMID:15731909 RGD:13702324 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Strada STE20 related adaptor alpha involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:14511394
(PMID:18854309)
(PMID:12805220)		 RGD PMID:12805220 PMID:18854309 PMID:14511394 RGD:1600691 NCBI chr10:91,094,849...91,123,890
Ensembl chr10:91,094,687...91,123,830 		JBrowse link
G Stradb STE20 related adaptor beta involved_in ISO (PMID:14517248) RGD PMID:14517248 NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (PMID:17960115) RGD PMID:17960115 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tom1l1 target of myb1 like 1 membrane trafficking protein involved_in ISO (PMID:16479011) RGD PMID:16479011 NCBI chr10:75,464,577...75,508,304
Ensembl chr10:75,464,577...75,508,250 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor involved_in ISO (PMID:14580337), (PMID:19801554) RGD PMID:14580337 PMID:19801554 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:17135271) RGD PMID:17135271 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in ISO (PMID:28096417) RGD PMID:28096417 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355 		JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846 		JBrowse link
G Dynap dynactin associated protein involved_in ISO (PMID:20978158) RGD PMID:20978158 NCBI chr18:63,885,164...63,909,464
Ensembl chr18:63,886,448...63,913,232 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18441324)		 UniProt
RGD		 PMID:18441324 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Gas6 growth arrest specific 6 involved_in IDA PMID:18374201 UniProt PMID:18374201 RGD:8554638 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:22351760) RGD PMID:22351760 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:8702995) RGD PMID:8702995 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insr insulin receptor involved_in ISO (PMID:7556070) RGD PMID:7556070 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 involved_in ISO (PMID:20616313) RGD PMID:20616313 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18295594)		 UniProt
RGD		 PMID:18295594 GO_REF:0000024 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Notch2 notch receptor 2 acts_upstream_of_or_within ISO (PMID:34635817) RGD PMID:34635817 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20682778)		 UniProt
RGD		 PMID:20682778 GO_REF:0000024 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO (PMID:9368760) RGD PMID:9368760 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:23180369)		 UniProt
RGD		 PMID:23180369 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Prkcz protein kinase C, zeta IMP in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (PMID:23827345) RGD PMID:23827345 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Tcl1a Tcl1 family Akt coactivator A involved_in ISO (PMID:28262547) RGD PMID:28262547 NCBI chr 6:124,125,032...124,131,025
Ensembl chr 6:124,125,032...124,131,025 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of ISO (PMID:20034610) RGD PMID:20034610 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
activation of protein kinase C activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in ISO (PMID:10713049) RGD PMID:10713049 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Lep leptin involved_in ISS
ISO		 GO_REF:0000024
(PMID:24340098)		 UniProt
RGD		 PMID:24340098 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Sez6 seizure related 6 homolog acts_upstream_of_or_within ISO MGI:1935121|MGI:2385295 (PMID:16814779) RGD PMID:16814779 NCBI chr10:62,818,931...62,868,686
Ensembl chr10:62,819,069...62,868,671 		JBrowse link
G Sez6l seizure related 6 homolog like acts_upstream_of_or_within ISO MGI:104745|MGI:2385295 (PMID:16814779) RGD PMID:16814779 NCBI chr12:44,064,901...44,221,814
Ensembl chr12:44,064,935...44,219,663 		JBrowse link
G Sez6l2 seizure related 6 homolog like 2 acts_upstream_of_or_within ISO MGI:104745|MGI:1935121 (PMID:16814779) RGD PMID:16814779 NCBI chr 1:181,557,109...181,577,456
Ensembl chr 1:181,557,109...181,577,456 		JBrowse link
activation of transmembrane receptor protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in ISO (PMID:19424712) RGD PMID:19424712 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit acts_upstream_of_or_within ISO MGI:2155602 (PMID:16162937) RGD PMID:16162937 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pdgfc platelet derived growth factor C acts_upstream_of_or_within ISO (PMID:10806482) RGD PMID:10806482 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Prlr prolactin receptor involved_in ISO (PMID:10585417) RGD PMID:10585417 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:18431508), (PMID:19524870)		 UniProt
RGD		 PMID:18431508 PMID:19524870 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16272156)		 UniProt
RGD		 PMID:16272156 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:18687677) RGD PMID:18687677 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spatc1l spermatogenesis and centriole associated 1-like acts_upstream_of_or_within ISO (PMID:30026308) RGD PMID:30026308 NCBI chr20:12,074,040...12,083,873
Ensembl chr20:12,074,047...12,083,301 		JBrowse link
positive regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stox1 storkhead box 1 involved_in ISO (PMID:22253775), (PMID:22995177) RGD PMID:22253775 PMID:22995177 NCBI chr20:30,598,284...30,666,371
Ensembl chr20:30,598,168...30,666,939 		JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ccnd1 cyclin D1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:8114739)		 UniProt
RGD		 PMID:8114739 GO_REF:0000024 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 involved_in ISO (PMID:8114739) RGD PMID:8114739 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccnd3 cyclin D3 involved_in ISO (PMID:8114739) RGD PMID:8114739 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccny cyclin Y involved_in ISO (PMID:19524571), (PMID:20059949) RGD PMID:19524571 PMID:20059949 NCBI chr17:57,385,002...57,512,860
Ensembl chr17:57,384,176...57,522,378 		JBrowse link
G Cdc6 cell division cycle 6 IMP RGD PMID:22223646 RGD:10045360 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 IDA RGD PMID:10721722 RGD:632478 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:22223646 RGD:10045360 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:18483258) RGD PMID:18483258 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:24313324) RGD PMID:24313324 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672 		JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 involved_in ISO (PMID:17310996) RGD PMID:17310996 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:18593906) RGD PMID:18593906 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:19210544) RGD PMID:19210544 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11900540)		 UniProt
RGD		 PMID:11900540 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,122
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 involved_in ISO (PMID:17310996) RGD PMID:17310996 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874 		JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:11687586), (PMID:19162005) RGD PMID:11687586 PMID:19162005 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Spdya speedy/RINGO cell cycle regulator family member A involved_in ISS
ISO		 GO_REF:0000024
(PMID:15611625)
(PMID:17151349)		 UniProt
RGD		 PMID:15611625 PMID:17151349 GO_REF:0000024 NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850 		JBrowse link
G Stil STIL, centriolar assembly protein acts_upstream_of_or_within ISO (PMID:16024801) RGD PMID:16024801 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:12743035), (PMID:18483258) RGD PMID:12743035 PMID:18483258 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19574994 RGD:2317913 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:2152037 (PMID:11481456) RGD PMID:11481456 NCBI chr 1:246,066,830...246,152,890
Ensembl chr 1:246,067,100...246,152,903 		JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor acts_upstream_of_or_within ISO MGI:2451038 (PMID:18323529) RGD PMID:18323529 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Arhgef5 Rho guanine nucleotide exchange factor 5 involved_in ISO (PMID:15601624) RGD PMID:15601624 NCBI chr 4:72,087,205...72,112,316
Ensembl chr 4:72,087,247...72,111,254 		JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO (PMID:12878610), (PMID:15579909) RGD PMID:12878610 PMID:15579909 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 acts_upstream_of ISO (PMID:16027136) RGD PMID:16027136 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:12813029), (PMID:15310755)
(PMID:18281285)		 RGD PMID:12813029 PMID:15310755 PMID:18281285 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dusp19 dual specificity phosphatase 19 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO (PMID:17593335)
(PMID:10829020)		 RGD PMID:10829020 PMID:17593335 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO (PMID:10523642) RGD PMID:10523642 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO (PMID:10650002) RGD PMID:10650002 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in ISO (PMID:10650002) RGD PMID:10650002 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 acts_upstream_of_or_within ISO MGI:106211 (PMID:18838382) RGD PMID:18838382 NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 acts_upstream_of_or_within IDA PMID:9668039 MGI PMID:9668039 RGD:1299389 NCBI chr11:84,399,989...84,551,013
Ensembl chr11:84,399,816...84,546,972 		JBrowse link
G Fzd4 frizzled class receptor 4 acts_upstream_of_or_within ISO MGI:1923484|MGI:2135272 (PMID:15195140) RGD PMID:15195140 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724 		JBrowse link
G Fzd5 frizzled class receptor 5 acts_upstream_of_or_within ISO (PMID:15195140) RGD PMID:15195140 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Fzd8 frizzled class receptor 8 acts_upstream_of_or_within ISO (PMID:15195140) RGD PMID:15195140 NCBI chr17:57,312,924...57,320,551
Ensembl chr17:57,314,450...57,320,650 		JBrowse link
G Il1b interleukin 1 beta IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:17379480) RGD PMID:17379480 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3 acts_upstream_of_or_within ISO MGI:108520|MGI:2135272 (PMID:15195140) RGD PMID:15195140 NCBI chr 2:191,514,726...191,717,048
Ensembl chr 2:191,518,506...191,716,735 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO (PMID:11959862) RGD PMID:11959862 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 involved_in IDA
ISO		 (PMID:10523642) RGD PMID:10523642 PMID:9110999 RGD:2293488 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 involved_in ISO (PMID:17584736) RGD PMID:17584736 NCBI chr 1:82,955,784...82,974,084
Ensembl chr 1:82,955,207...82,974,084 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 involved_in ISO (PMID:17584736) RGD PMID:17584736 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in ISO (PMID:27511108) RGD PMID:27511108 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 involved_in ISO (PMID:27511108) RGD PMID:27511108 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:9305639)
(PMID:16157600)
(PMID:12878610)		 RGD PMID:9305639 PMID:12878610 PMID:16157600 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in IMP
ISO		 (PMID:23000344) RGD PMID:23000344 PMID:20716917 RGD:10412640 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:11460167)		 UniProt
RGD		 PMID:11460167 GO_REF:0000024 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 involved_in ISO (PMID:17584736) RGD PMID:17584736 NCBI chr 1:203,645,098...203,660,782
Ensembl chr 1:203,645,153...203,660,331 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 acts_upstream_of_or_within
involved_in		 ISO (PMID:15767678)
(PMID:10523642)		 RGD PMID:10523642 PMID:15767678 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mir92a1 microRNA 92a-1 involved_in ISO (PMID:24332650) RGD PMID:24332650 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413 		JBrowse link
G Mir92a2 microRNA 92a-2 involved_in ISO (PMID:24332650) RGD PMID:24332650 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:8805275)		 UniProt
RGD		 PMID:8805275 PMID:8805275 GO_REF:0000024, RGD:8554570 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15226266 RGD:1642623 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 acts_upstream_of ISO (PMID:15465829) RGD PMID:15465829 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25825749 RGD:11537351 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Sash1 SAM and SH3 domain containing 1 acts_upstream_of_or_within ISO (PMID:23776175) RGD PMID:23776175 NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO MGI:2384078 (PMID:9000133) RGD PMID:9000133 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISO (PMID:11278723) RGD PMID:11278723 NCBI chr12:39,312,354...39,473,656
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:16203995 RGD:10043312 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Tlr6 toll-like receptor 6 acts_upstream_of_or_within ISO (PMID:10231569) RGD PMID:10231569 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:17389591) RGD PMID:17389591 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in ISO (PMID:12296995) RGD PMID:12296995 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:11907583) RGD PMID:11907583 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:11751921) RGD PMID:11751921 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 acts_upstream_of_or_within ISO MGI:108520|MGI:1923484 (PMID:15195140) RGD PMID:15195140 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:20034610)
MGI:1857617 (PMID:19300477)		 RGD PMID:19300477 PMID:20034610 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within ISO MGI:2387499|MGI:2684610 (PMID:17644613) RGD PMID:17644613 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam9 ADAM metallopeptidase domain 9 acts_upstream_of ISO (PMID:17704059) RGD PMID:17704059 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:19477270) RGD PMID:19477270 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Ajuba ajuba LIM protein acts_upstream_of_or_within ISO (PMID:10330178) RGD PMID:10330178 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Akap13 A-kinase anchoring protein 13 involved_in IMP PMID:23716597 UniProt PMID:23716597 RGD:11059588 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Cd24 CD24 molecule involved_in ISS
ISO		 PMID:12496407
(PMID:12496407)
GO_REF:0000024		 RGD
UniProt		 PMID:12496407 PMID:12496407 GO_REF:0000024, RGD:8554185 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within IDA PMID:11994468 MGI PMID:11994468 RGD:625644 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cripto cripto, EGF-CFC family member acts_upstream_of_or_within ISO (PMID:9013573) RGD PMID:9013573 NCBI chr 8:110,924,774...110,938,545
Ensembl chr 8:110,925,024...110,930,308 		JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Diras1 DIRAS family GTPase 1 NOT|involved_in ISO (PMID:12194967) RGD PMID:12194967 NCBI chr 7:8,687,964...8,692,828
Ensembl chr 7:8,687,942...8,693,831 		JBrowse link
G Diras2 DIRAS family GTPase 2 NOT|involved_in ISO (PMID:12194967) RGD PMID:12194967 NCBI chr17:12,730,040...12,761,511
Ensembl chr17:12,725,149...12,761,663 		JBrowse link
G Drd4 dopamine receptor D4 acts_upstream_of ISO (PMID:9843378) RGD PMID:9843378 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:10770212) RGD PMID:10770212 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn3 endothelin 3 involved_in ISO (PMID:10770212) RGD PMID:10770212 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 involved_in ISO (PMID:10572067) RGD PMID:10572067 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 acts_upstream_of_or_within ISO (PMID:22064321) RGD PMID:22064321 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) RGD PMID:20154697 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fcer1a Fc epsilon receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) RGD PMID:9000133 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO (PMID:16756958) RGD PMID:16756958 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in ISO (PMID:16756958) RGD PMID:16756958 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:16756958) RGD PMID:16756958 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 involved_in ISO (PMID:8622701) RGD PMID:8622701 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 involved_in ISO (PMID:9299537) RGD PMID:9299537 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Gab1 GRB2-associated binding protein 1 acts_upstream_of_or_within ISO MGI:2667211 (PMID:12808090) RGD PMID:12808090 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236 		JBrowse link
G Gdf9 growth differentiation factor 9 involved_in ISO (PMID:24313324) RGD PMID:24313324 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672 		JBrowse link
G Ghr growth hormone receptor acts_upstream_of IDA PMID:8063815 BHF-UCL PMID:8063815 RGD:8553732 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:26375174) RGD PMID:26375174 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) RGD PMID:23027131 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:15087293 RGD:1624373 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il34 interleukin 34 acts_upstream_of_or_within ISO (PMID:26754294) RGD PMID:26754294 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000 		JBrowse link
G Ilk integrin-linked kinase IMP inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Insr insulin receptor acts_upstream_of ISO (PMID:17001305) RGD PMID:17001305 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 IMP RGD PMID:23987506 RGD:11049533 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:17379480) RGD PMID:17379480 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:96974|MGI:97306 (PMID:10620616) RGD PMID:10620616 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO MGI:96677|MGI:97306 (PMID:10620616) RGD PMID:10620616 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:10969813 RGD:1600497 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Maged1 MAGE family member D1 involved_in ISO (PMID:19268530) RGD PMID:19268530 NCBI chr  X:59,422,715...59,429,381
Ensembl chr  X:59,422,717...59,429,364 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 acts_upstream_of_or_within ISO (PMID:14744933) RGD PMID:14744933 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:10364264) RGD PMID:10364264 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mst1r macrophage stimulating 1 receptor involved_in ISO (PMID:12676986) RGD PMID:12676986 NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455 		JBrowse link
G Nek10 NIMA-related kinase 10 involved_in ISO (PMID:20956560) RGD PMID:20956560 NCBI chr15:10,387,063...10,564,177
Ensembl chr15:10,381,140...10,559,722 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (PMID:17942966) RGD PMID:17942966 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 acts_upstream_of ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:17306762) RGD PMID:17306762 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17360971)		 UniProt
RGD		 PMID:17360971 GO_REF:0000024 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in ISO (PMID:19127022) RGD PMID:19127022 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISS
ISO		 GO_REF:0000024
(PMID:11788434)		 UniProt
RGD		 PMID:11788434 GO_REF:0000024 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IDA
ISO		 PMID:19460854
(PMID:11788434), (PMID:17942966), (PMID:9685360)		 RGD PMID:9685360 PMID:11788434 PMID:17942966 PMID:19460854 RGD:8554838 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:17942966)		 UniProt
RGD		 PMID:17942966 GO_REF:0000024 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma involved_in ISO (PMID:12507995) RGD PMID:12507995 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 involved_in ISO (PMID:12507995) RGD PMID:12507995 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374 		JBrowse link
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 involved_in ISO (PMID:19906996) RGD PMID:19906996 NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243 		JBrowse link
G Pla2g1b phospholipase A2 group IB acts_upstream_of ISO (PMID:15528384), (PMID:16005851) RGD PMID:15528384 PMID:16005851 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:16935468 RGD:1642549 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:15896720) RGD PMID:15896720 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:9254656) RGD PMID:9254656 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:15899849) RGD PMID:15899849 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO (PMID:21385766) RGD PMID:21385766 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IMP RGD PMID:11941412 RGD:150523765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 IMP RGD PMID:21607062 RGD:5508182 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Tenm1 teneurin transmembrane protein 1 involved_in ISO (PMID:22698694) RGD PMID:22698694 NCBI chr  X:121,400,466...122,289,877
Ensembl chr  X:121,403,649...122,290,207 		JBrowse link
G Thbs1 thrombospondin 1 acts_upstream_of ISO (PMID:17413041) RGD PMID:17413041 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of ISO (PMID:20051628) RGD PMID:20051628 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of
involved_in		 ISO (PMID:10748004)
(PMID:12813029), (PMID:17389591)		 RGD PMID:10748004 PMID:12813029 PMID:17389591 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO (PMID:15304486) RGD PMID:15304486 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO (PMID:14761963) RGD PMID:14761963 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen acts_upstream_of_or_within ISO (PMID:23775122) RGD PMID:23775122 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23990668)		 UniProt
RGD		 PMID:23990668 GO_REF:0000024 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Dipk2a divergent protein kinase domain 2A involved_in ISO UniProtKB:P09216 (PMID:24269490) RGD PMID:24269490 NCBI chr 8:95,070,695...95,089,815
Ensembl chr 8:95,030,279...95,089,815 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:22732145) RGD PMID:22732145 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate IDA RGD PMID:16341931 RGD:9685306 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25825749 RGD:11537351 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Tcim transcriptional and immune response regulator involved_in ISO (PMID:15087392) RGD PMID:15087392 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:12086864) RGD PMID:12086864 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qtnf9 C1q and TNF related 9 acts_upstream_of_or_within IMP
ISO
IDA		 PMID:23842676
(PMID:23842676)		 RGD PMID:23842676 PMID:23842676 PMID:23842676 RGD:13507306, RGD:13507306 NCBI chr15:34,907,791...34,922,985
Ensembl chr15:34,911,286...34,922,980 		JBrowse link
G Cab39 calcium binding protein 39 involved_in ISO (PMID:19892943), (PMID:24393035) RGD PMID:19892943 PMID:24393035 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I involved_in ISS
ISO		 GO_REF:0000024
(PMID:17442826)		 UniProt
RGD		 PMID:17442826 GO_REF:0000024 NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081 		JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17975111)		 UniProt
RGD		 PMID:17975111 GO_REF:0000024 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:20080667)
(PMID:19903888), (PMID:20080667)		 RGD PMID:19903888 PMID:20080667 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:23413191) RGD PMID:23413191 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Etaa1 ETAA1 activator of ATR kinase involved_in ISO (PMID:27723717), (PMID:27723720) RGD PMID:27723717 PMID:27723720 NCBI chr14:92,298,461...92,314,044
Ensembl chr14:92,299,553...92,314,104 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) RGD PMID:20154697 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO (PMID:25683712) RGD PMID:25683712 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19549901)		 UniProt
RGD		 PMID:19549901 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP Akt1 RGD PMID:18443201 RGD:4108490 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:22504299) RGD PMID:22504299 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:28389568) RGD PMID:28389568 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in ISO (PMID:8388392) RGD PMID:8388392 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in ISO (PMID:8388392) RGD PMID:8388392 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO (PMID:20332113) RGD PMID:20332113 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Pih1d1 PIH1 domain containing 1 involved_in ISO (PMID:24036451) RGD PMID:24036451 NCBI chr 1:95,639,597...95,645,295
Ensembl chr 1:95,639,592...95,645,290 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase involved_in ISO (PMID:16186805) RGD PMID:16186805 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in ISO (PMID:20080667) RGD PMID:20080667 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ralb RAS like proto-oncogene B involved_in ISO (PMID:24056301) RGD PMID:24056301 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202 		JBrowse link
G Rhoa ras homolog family member A involved_in ISS
ISO		 GO_REF:0000024
(PMID:8617235)		 UniProt
RGD		 PMID:8617235 GO_REF:0000024 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Slc8a2 solute carrier family 8 member A2 acts_upstream_of_or_within ISO (PMID:29274751) RGD PMID:29274751 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072 		JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:21127069) RGD PMID:21127069 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:19059439) RGD PMID:19059439 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Syap1 synapse associated protein 1 involved_in ISO (PMID:23300339) RGD PMID:23300339 NCBI chr  X:31,792,180...31,826,672
Ensembl chr  X:31,792,193...31,826,667 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Tead1 TEA domain transcription factor 1 acts_upstream_of_or_within ISO (PMID:18978355) RGD PMID:18978355 NCBI chr 1:166,791,900...167,010,591
Ensembl chr 1:166,792,628...167,003,369 		JBrowse link
positive regulation of protein tyrosine kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi1 abl-interactor 1 acts_upstream_of_or_within ISO (PMID:17101133) RGD PMID:17101133 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792 		JBrowse link
G Agrn agrin involved_in ISO (PMID:19376779) RGD PMID:19376779 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003 		JBrowse link
G Cass4 Cas scaffold protein family member 4 involved_in ISO (PMID:18256281) RGD PMID:18256281 NCBI chr 3:161,162,520...161,202,523
Ensembl chr 3:161,163,436...161,202,186 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO (PMID:7681396) RGD PMID:7681396 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Dok7 docking protein 7 involved_in ISO (PMID:20603078) RGD PMID:20603078 NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 acts_upstream_of_or_within ISO MGI:98956 (PMID:19920076) RGD PMID:19920076 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Efna1 ephrin A1 involved_in ISO UniProtKB:P54764 (PMID:24217950) RGD PMID:24217950 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Egf epidermal growth factor acts_upstream_of_or_within ISO (PMID:7678348) RGD PMID:7678348 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO ComplexPortal:CPX-1134 (PMID:24658113) RGD PMID:24658113 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B involved_in ISO (PMID:23169819) RGD PMID:23169819 NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:17077323) RGD PMID:17077323 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Il34 interleukin 34 acts_upstream_of_or_within ISO (PMID:26754294) RGD PMID:26754294 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000 		JBrowse link
G Lilra5 leukocyte immunoglobulin like receptor A5 involved_in ISO (PMID:19009525) RGD PMID:19009525 NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 involved_in ISO (PMID:18256281) RGD PMID:18256281 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (PMID:27525436) RGD PMID:27525436 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (PMID:21216966) RGD PMID:21216966 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Reln reelin involved_in ISO (PMID:21852430) RGD PMID:21852430 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17525734)		 UniProt
RGD		 PMID:17525734 GO_REF:0000024 NCBI chr10:82,502,911...82,569,882
Ensembl chr10:82,504,393...82,571,040 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:22492652) RGD PMID:22492652 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Unc119 unc-119 lipid binding chaperone involved_in ISO (PMID:14757743) RGD PMID:14757743 NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:106613 (PMID:19920076) RGD PMID:19920076 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13554
      regulation of molecular function 1784
        regulation of catalytic activity 1187
          regulation of transferase activity 596
            positive regulation of transferase activity 355
              positive regulation of kinase activity 312
                positive regulation of protein kinase activity 295
                  activation of protein kinase activity + 74
                  positive regulation of cyclin-dependent protein kinase activity + 20
                  positive regulation of protein serine/threonine kinase activity + 166
                  positive regulation of protein tyrosine kinase activity + 25
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13554
      regulation of biological process 13131
        regulation of cellular process 12768
          regulation of metabolic process 6743
            regulation of macromolecule metabolic process 6216
              regulation of protein metabolic process 2178
                regulation of protein modification process 1194
                  regulation of protein phosphorylation 919
                    positive regulation of protein phosphorylation 593
                      positive regulation of protein kinase activity 295
                        activation of protein kinase activity + 74
                        positive regulation of cyclin-dependent protein kinase activity + 20
                        positive regulation of protein serine/threonine kinase activity + 166
                        positive regulation of protein tyrosine kinase activity + 25
paths to the root