1,2-dichloroethane decreases expression ISO RGD:732665 6480464 ethylene dichloride results in decreased expression of PDPK1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions ISO RGD:732665 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PDPK1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol affects expression ISO RGD:732665 6480464 Ethinyl Estradiol affects the expression of PDPK1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PDPK1 mRNA CTD PMID:29097150 17alpha-ethynylestradiol multiple interactions ISO RGD:732665 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDPK1 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:732664 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of PDPK1 mRNA CTD PMID:17404688 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732665 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PDPK1 mRNA, [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of PDPK1 mRNA CTD PMID:17942748 , PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PDPK1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732665 6480464 Tetrachlorodibenzodioxin affects the expression of PDPK1 mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of PDPK1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of PDPK1 mRNA CTD PMID:21346803 2-methylcholine affects expression ISO RGD:732664 6480464 beta-methylcholine affects the expression of PDPK1 mRNA CTD PMID:21179406 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of PDPK1 mRNA CTD PMID:30071829 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PDPK1 protein CTD PMID:34915118 4,4'-diaminodiphenylmethane affects expression ISO RGD:732665 6480464 4, 4'-diaminodiphenylmethane affects the expression of PDPK1 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol decreases methylation ISO RGD:732665 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of PDPK1 exon CTD PMID:33297965 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of PDPK1 mRNA CTD PMID:36041667 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:732665 6480464 6-chloro-2 more ... CTD PMID:26450947 7,12-dimethyltetraphene increases expression ISO RGD:732665 6480464 9 more ... CTD PMID:32553695 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of PDPK1 mRNA CTD PMID:31881176 acrolein multiple interactions ISO RGD:732664 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PDPK1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PDPK1 mRNA CTD PMID:32699268 aflatoxin B1 multiple interactions ISO RGD:732664 6480464 [CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of PDPK1 protein, MIR138-1 mRNA alternative form inhibits the reaction [[CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of PDPK1 protein] CTD PMID:26084420 alpha-pinene multiple interactions ISO RGD:732664 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PDPK1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PDPK1 mRNA CTD PMID:32699268 amiloride decreases phosphorylation ISO RGD:732664 6480464 Amiloride results in decreased phosphorylation of PDPK1 protein CTD PMID:16059913 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PDPK1 mRNA CTD PMID:16483693 aristolochic acid A increases expression ISO RGD:732664 6480464 aristolochic acid I results in increased expression of PDPK1 mRNA CTD PMID:33212167 arsenite(3-) decreases activity ISO RGD:732665 6480464 arsenite results in decreased activity of PDPK1 protein CTD PMID:17520061 arsenite(3-) multiple interactions ISO RGD:732664 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PDPK1 mRNA] CTD PMID:32406909 arsenous acid decreases activity ISO RGD:732664 6480464 Arsenic Trioxide results in decreased activity of PDPK1 protein CTD PMID:14633726 arsenous acid increases expression ISO RGD:732665 6480464 Arsenic Trioxide results in increased expression of PDPK1 mRNA CTD PMID:32781346 arsenous acid decreases expression ISO RGD:732665 6480464 Arsenic Trioxide results in decreased expression of PDPK1 mRNA CTD PMID:30032600 Asiaticoside multiple interactions EXP 6480464 asiaticoside inhibits the reaction [Rotenone results in decreased expression of PDPK1 mRNA], asiaticoside inhibits the reaction [Rotenone results in decreased expression of PDPK1 protein] CTD PMID:28238857 atorvastatin calcium multiple interactions ISO RGD:732664 6480464 [Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of and results in decreased expression of PDPK1 protein CTD PMID:18172863 benzo[a]pyrene increases expression ISO RGD:732665 6480464 Benzo(a)pyrene results in increased expression of PDPK1 mRNA CTD PMID:22228805 benzo[a]pyrene increases methylation ISO RGD:732664 6480464 Benzo(a)pyrene results in increased methylation of PDPK1 3' UTR CTD PMID:27901495 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:732664 6480464 7 more ... CTD PMID:19150397 beryllium sulfate decreases expression ISO RGD:732664 6480464 beryllium sulfate results in decreased expression of PDPK1 mRNA CTD PMID:35679967 bis(2-ethylhexyl) phthalate increases expression ISO RGD:732665 6480464 Diethylhexyl Phthalate results in increased expression of PDPK1 mRNA CTD PMID:24804967 bisphenol A increases expression ISO RGD:732665 6480464 bisphenol A results in increased expression of PDPK1 mRNA CTD PMID:26063408 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of PDPK1 mRNA CTD PMID:36041667 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PDPK1 mRNA CTD PMID:25181051 , PMID:29097150 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of PDPK1 mRNA CTD PMID:36041667 cadmium atom increases expression ISO RGD:732664 6480464 Cadmium results in increased expression of PDPK1 protein CTD PMID:14499349 cadmium dichloride increases expression ISO RGD:732664 6480464 Cadmium Chloride results in increased expression of PDPK1 mRNA CTD PMID:33129824 caffeine affects phosphorylation ISO RGD:732664 6480464 Caffeine affects the phosphorylation of PDPK1 protein CTD PMID:35688186 calcidiol increases expression EXP 6480464 Calcifediol deficiency results in increased expression of PDPK1 mRNA CTD PMID:17293106 carbamazepine affects expression ISO RGD:732664 6480464 Carbamazepine affects the expression of PDPK1 mRNA CTD PMID:24752500 carbon nanotube decreases expression ISO RGD:732665 6480464 Nanotubes, Carbon analog results in decreased expression of PDPK1 mRNA CTD PMID:25554681 celecoxib multiple interactions ISO RGD:732664 6480464 [Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of and results in decreased expression of PDPK1 protein CTD PMID:18172863 celecoxib decreases activity ISO RGD:732664 6480464 Celecoxib analog results in decreased activity of PDPK1 protein, Celecoxib results in decreased activity of PDPK1 protein CTD PMID:12000750 , PMID:15499625 CGP 52608 multiple interactions ISO RGD:732664 6480464 CGP 52608 promotes the reaction [RORA protein binds to PDPK1 gene] CTD PMID:28238834 ciguatoxin CTX1B affects expression ISO RGD:732665 6480464 Ciguatoxins affects the expression of PDPK1 mRNA CTD PMID:18353800 cisplatin decreases expression ISO RGD:732664 6480464 Cisplatin results in decreased expression of PDPK1 mRNA CTD PMID:25450742 cocaine affects expression EXP 6480464 Cocaine affects the expression of PDPK1 mRNA CTD PMID:20187946 copper atom multiple interactions ISO RGD:732664 6480464 [Chelating Agents binds to Copper] which results in increased expression of PDPK1 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:732664 6480464 [Chelating Agents binds to Copper] which results in increased expression of PDPK1 mRNA CTD PMID:30911355 crocidolite asbestos decreases expression ISO RGD:732664 6480464 Asbestos, Crocidolite results in decreased expression of PDPK1 protein modified form CTD PMID:21570478 crocidolite asbestos decreases phosphorylation ISO RGD:732664 6480464 Asbestos, Crocidolite results in decreased phosphorylation of PDPK1 protein CTD PMID:17191120 curcumin decreases phosphorylation ISO RGD:732664 6480464 Curcumin results in decreased phosphorylation of PDPK1 protein CTD PMID:34634291 cyclosporin A decreases expression ISO RGD:732664 6480464 Cyclosporine results in decreased expression of PDPK1 mRNA CTD PMID:25562108 diarsenic trioxide decreases activity ISO RGD:732664 6480464 Arsenic Trioxide results in decreased activity of PDPK1 protein CTD PMID:14633726 diarsenic trioxide increases expression ISO RGD:732665 6480464 Arsenic Trioxide results in increased expression of PDPK1 mRNA CTD PMID:32781346 diarsenic trioxide decreases expression ISO RGD:732665 6480464 Arsenic Trioxide results in decreased expression of PDPK1 mRNA CTD PMID:30032600 diclofenac affects expression ISO RGD:732664 6480464 Diclofenac affects the expression of PDPK1 mRNA CTD PMID:24752500 doxorubicin decreases response to substance ISO RGD:732664 6480464 PDPK1 protein results in decreased susceptibility to Doxorubicin CTD PMID:16782806 doxorubicin decreases expression ISO RGD:732665 6480464 Doxorubicin results in decreased expression of PDPK1 protein CTD PMID:19429709 , PMID:26450947 doxorubicin multiple interactions ISO RGD:732665 6480464 6-chloro-2 more ... CTD PMID:26450947 elemental selenium multiple interactions ISO RGD:732664 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of PDPK1 mRNA CTD PMID:19244175 finasteride increases expression EXP 6480464 Finasteride results in increased expression of PDPK1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:732665 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PDPK1 mRNA CTD PMID:22206623 gemcitabine decreases response to substance ISO RGD:732664 6480464 PDPK1 protein modified form results in decreased susceptibility to Gemcitabine CTD PMID:16782806 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PDPK1 mRNA CTD PMID:33387578 glyphosate decreases expression ISO RGD:732664 6480464 glyphosate results in decreased expression of PDPK1 mRNA CTD PMID:31295307 Goe 6976 decreases activity ISO RGD:732664 6480464 Go 6976 results in decreased activity of PDPK1 protein CTD PMID:10998351 hydrogen peroxide multiple interactions ISO RGD:732665 6480464 PI103 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of PDPK1 protein], Quercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of PDPK1 protein] CTD PMID:27494022 hydrogen peroxide increases phosphorylation ISO RGD:732665 6480464 Hydrogen Peroxide results in increased phosphorylation of PDPK1 protein CTD PMID:27494022 hydroquinone decreases activity ISO RGD:732665 6480464 hydroquinone metabolite results in decreased activity of PDPK1 protein, hydroquinone results in decreased activity of PDPK1 protein CTD PMID:20054000 icariside II decreases phosphorylation ISO RGD:732664 6480464 baohuoside I results in decreased phosphorylation of PDPK1 protein CTD PMID:25119583 ivermectin decreases expression ISO RGD:732664 6480464 Ivermectin results in decreased expression of PDPK1 protein CTD PMID:32959892 lead diacetate decreases expression ISO RGD:732665 6480464 lead acetate results in decreased expression of PDPK1 mRNA CTD PMID:20542052 lipopolysaccharide multiple interactions ISO RGD:732664 6480464 Amino Acids more ... CTD PMID:22003094 lipopolysaccharide multiple interactions ISO RGD:732665 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of PDPK1 protein] CTD PMID:23735482 lipopolysaccharide increases phosphorylation ISO RGD:732665 6480464 Lipopolysaccharides results in increased phosphorylation of PDPK1 protein CTD PMID:20054000 , PMID:23735482 lipopolysaccharide increases phosphorylation ISO RGD:732664 6480464 Lipopolysaccharides results in increased phosphorylation of PDPK1 protein CTD PMID:22003094 maleic acid decreases expression ISO RGD:732664 6480464 maleic acid results in decreased expression of PDPK1 mRNA CTD PMID:28392987 mechlorethamine increases expression ISO RGD:732665 6480464 Mechlorethamine results in increased expression of PDPK1 protein modified form CTD PMID:25891025 metformin decreases expression ISO RGD:732664 6480464 Metformin results in decreased expression of PDPK1 mRNA CTD PMID:32589349 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of PDPK1 mRNA CTD PMID:30467583 microcystin-LR increases phosphorylation ISO RGD:732664 6480464 cyanoginosin LR results in increased phosphorylation of PDPK1 protein CTD PMID:20421190 N-ethyl-N-nitrosourea increases expression ISO RGD:732665 6480464 Ethylnitrosourea results in increased expression of PDPK1 protein CTD PMID:32902906 N-methyl-N-nitrosourea multiple interactions EXP 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein, Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein] CTD PMID:25164625 N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions ISO RGD:732664 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased phosphorylation of PDPK1 protein] CTD PMID:17136479 N-tosyl-L-phenylalanyl chloromethyl ketone decreases activity ISO RGD:732664 6480464 Tosylphenylalanyl Chloromethyl Ketone results in decreased activity of PDPK1 protein CTD PMID:17136479 ochratoxin A decreases methylation EXP 6480464 ochratoxin A results in decreased methylation of PDPK1 gene CTD PMID:26431795 OSU-03012 multiple interactions ISO RGD:732664 6480464 OSU 03012 binds to and results in decreased activity of PDPK1 protein CTD PMID:15205346 OSU-03012 decreases response to substance ISO RGD:732664 6480464 PDPK1 protein modified form results in decreased susceptibility to OSU 03012 CTD PMID:15205346 ozone multiple interactions ISO RGD:732664 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PDPK1 mRNA more ... CTD PMID:32699268 paclitaxel decreases response to substance ISO RGD:732664 6480464 PDPK1 protein results in decreased susceptibility to Paclitaxel CTD PMID:16782806 paracetamol decreases expression ISO RGD:732664 6480464 Acetaminophen results in decreased expression of PDPK1 mRNA CTD PMID:22230336 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of PDPK1 mRNA CTD PMID:33387578 pentanal decreases expression ISO RGD:732664 6480464 pentanal results in decreased expression of PDPK1 mRNA CTD PMID:26079696 perfluorododecanoic acid decreases activity EXP 6480464 perfluorododecanoic acid results in decreased activity of PDPK1 protein CTD PMID:23353032 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of PDPK1 protein, perfluorododecanoic acid results in decreased expression of PDPK1 protein modified form CTD PMID:23353032 phenobarbital decreases expression ISO RGD:732665 6480464 Phenobarbital results in decreased expression of PDPK1 mRNA CTD PMID:23091169 pirinixic acid increases expression ISO RGD:732665 6480464 pirinixic acid results in increased expression of PDPK1 mRNA CTD PMID:18301758 progesterone multiple interactions ISO RGD:732664 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of PDPK1 mRNA CTD PMID:17404688 quercetin multiple interactions ISO RGD:732665 6480464 Quercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of PDPK1 protein], Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of PDPK1 protein] CTD PMID:23735482 , PMID:27494022 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein] CTD PMID:25164625 resveratrol multiple interactions ISO RGD:732664 6480464 resveratrol inhibits the reaction [EGF protein results in increased phosphorylation of PDPK1 protein] CTD PMID:16343977 resveratrol multiple interactions ISO RGD:732665 6480464 6-chloro-2 more ... CTD PMID:20980258 , PMID:26450947 resveratrol decreases expression ISO RGD:732665 6480464 resveratrol results in decreased expression of PDPK1 mRNA CTD PMID:22610192 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PDPK1 mRNA, Rotenone results in decreased expression of PDPK1 protein CTD PMID:28238857 rotenone multiple interactions EXP 6480464 [Levodopa co-treated with Rotenone] results in decreased expression of PDPK1 mRNA more ... CTD PMID:28238857 selenium atom multiple interactions ISO RGD:732664 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of PDPK1 mRNA CTD PMID:19244175 silver atom decreases expression ISO RGD:732665 6480464 Silver results in decreased expression of PDPK1 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:732665 6480464 Silver results in decreased expression of PDPK1 mRNA CTD PMID:27131904 sirtinol multiple interactions ISO RGD:732665 6480464 sirtinol inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in decreased expression of PDPK1 protein]] CTD PMID:26450947 testosterone multiple interactions EXP 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein, Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein] CTD PMID:25164625 titanium dioxide increases expression ISO RGD:732665 6480464 titanium dioxide results in increased expression of PDPK1 mRNA CTD PMID:23557971 trichostatin A affects expression ISO RGD:732664 6480464 trichostatin A affects the expression of PDPK1 mRNA CTD PMID:28542535 Triptolide increases expression EXP 6480464 triptolide results in increased expression of PDPK1 mRNA CTD PMID:23639586 triptonide increases expression ISO RGD:732665 6480464 triptonide results in increased expression of PDPK1 mRNA CTD PMID:33045310 troglitazone decreases expression ISO RGD:732665 6480464 troglitazone results in decreased expression of PDPK1 mRNA CTD PMID:28973697 urethane increases expression ISO RGD:732664 6480464 Urethane results in increased expression of PDPK1 mRNA CTD PMID:28818685 valproic acid increases expression ISO RGD:732664 6480464 Valproic Acid results in increased expression of PDPK1 mRNA CTD PMID:23179753 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of PDPK1 mRNA CTD PMID:29427782 venlafaxine hydrochloride affects expression EXP 6480464 Venlafaxine Hydrochloride affects the expression of PDPK1 mRNA CTD PMID:25423262 vitamin E multiple interactions ISO RGD:732664 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of PDPK1 mRNA CTD PMID:19244175 vitamin E decreases expression ISO RGD:732664 6480464 Vitamin E results in decreased expression of PDPK1 mRNA CTD PMID:19244175
