regulation of protein modification process - Ontology Report

RGD

PMID:9314843

RGD:6478796

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

Ghr

growth hormone receptor

RGD

PMID:11244571

RGD:1624962

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

Il3

interleukin 3

acts_upstream_of_or_within

(MGI:63384|PMID:8378315)

PMID:8378315

MGI:63384

NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066

Il4

interleukin 4

involved_in

UniProtKB:P08575 (PMID:12574355)
PMID:21873635

PMID:12574355 PMID:21873635

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

Jak2

Janus kinase 2

involved_in

GO_REF:0000024
(MGI:4457458|PMID:20304997)

PMID:20304997

GO_REF:0000024 MGI:4457458

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Pibf1

progesterone immunomodulatory binding factor 1

involved_in

(PMID:16393965)

PMID:16393965

NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712

Prl3d4

prolactin family 3, subfamily D, member 4

RGD

PMID:8822264

RGD:1298822

NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667

Prlr

prolactin receptor

involved_in

GO_REF:0000107
(PMID:10585417)

PMID:10585417

GO_REF:0000107

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

Ptk2b

protein tyrosine kinase 2 beta

involved_in

IMP
ISO

(PMID:8670418)

PMID:8670418 PMID:11818507

RGD:633057

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

activation of NF-kappaB-inducing kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Agt

angiotensinogen

acts_upstream_of_or_within

(MGI:3844151|PMID:19404405)

PMID:19404405

MGI:3844151

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

Card10

caspase recruitment domain family, member 10

involved_in

(PMID:11259443)

PMID:11259443

NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224

Chi3l1

chitinase 3 like 1

involved_in

GO_REF:0000024
(MGI:5306542|PMID:21546314)

PMID:21546314

GO_REF:0000024 MGI:5306542

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

Cops8

COP9 signalosome subunit 8

involved_in

(PMID:22992343)

PMID:22992343

NCBI chr 9:91,207,427...91,217,258
Ensembl chr 9:91,207,395...91,217,258

Ikbkg

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

acts_upstream_of_or_within

(MGI:2682548|PMID:14654787)

PMID:14654787

MGI:2682548

NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499

Irak1

interleukin-1 receptor-associated kinase 1

involved_in

(PMID:11397809)

PMID:11397809

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

Irak2

interleukin-1 receptor-associated kinase 2

NOT|acts_upstream_of_or_within

(MGI:2388552|PMID:12220507)

PMID:12220507

MGI:2388552

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

Malt1

MALT1 paracaspase

involved_in

(PMID:15125833)

PMID:15125833

NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260

Map3k7

mitogen activated protein kinase kinase kinase 7

involved_in

(PMID:10094049), (PMID:15125833)

PMID:10094049 PMID:15125833

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

Mas1

MAS1 proto-oncogene, G protein-coupled receptor

acts_upstream_of_or_within

MGI:2158808 (MGI:3844151|PMID:19404405)

PMID:19404405

MGI:3844151

NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709

Tirap

TIR domain containing adaptor protein

involved_in

(PMID:24275656)

PMID:24275656

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

Tnfsf15

TNF superfamily member 15

acts_upstream_of_or_within
involved_in

(PMID:11911831)
GO_REF:0000107

PMID:11911831

GO_REF:0000107

NCBI chr 5:77,140,099...77,156,142
Ensembl chr 5:77,139,878...77,156,228

Traf2

Tnf receptor-associated factor 2

involved_in

(PMID:15125833)

PMID:15125833

NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538

Traf4

Tnf receptor associated factor 4

involved_in

GO_REF:0000002

InterPro

GO_REF:0000002

NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284

Traf6

TNF receptor associated factor 6

involved_in

(PMID:15125833)
GO_REF:0000107

PMID:15125833

GO_REF:0000107

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Zfp91

zinc finger protein 91

involved_in

(PMID:20682767)

PMID:20682767

NCBI chr 1:209,891,344...209,928,890
Ensembl chr 1:209,891,344...209,927,762

activation of protein kinase A activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcy8

adenylate cyclase 8

involved_in

PMID:25381556

UniProt

PMID:25381556

RGD:13825194

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

Fbn1

fibrillin 1

involved_in

(PMID:27087445)

PMID:27087445

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

Prrc1

proline-rich coiled-coil 1

involved_in

PMID:21873635

GO_Central

NCBI chr18:50,812,548...50,846,273
Ensembl chr18:50,812,552...50,849,476

urocortin

RGD

NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950

activation of protein kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adnp

activity-dependent neuroprotector homeobox

Fyn kinase

RGD

PMID:19047645

RGD:2312772

NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312

Adra2a

adrenoceptor alpha 2A

involved_in

(PMID:15653687)

PMID:15653687

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Axin1

axin 1

involved_in

(PMID:9601641)
GO_REF:0000107

PMID:9601641

GO_REF:0000107

NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615

Bora

bora, aurora kinase A activator

involved_in

PMID:21873635

GO_Central

NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322

Cab39

calcium binding protein 39

acts_upstream_of_or_within
involved_in

(MGI:3836081|PMID:18854309)
(PMID:19892943)

PMID:18854309 PMID:19892943

MGI:3836081

NCBI chr 9:86,463,008...86,524,545
Ensembl chr 9:86,463,095...86,524,544

Calca

calcitonin-related polypeptide alpha

involved_in

(PMID:17983652)

PMID:17983652

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

Camkk1

calcium/calmodulin-dependent protein kinase kinase 1

PMID:16054095 PMID:21873635

RGD

PMID:16054095

RGD:2311420

NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498

Camkk2

calcium/calmodulin-dependent protein kinase kinase 2

involved_in

IDA
IBA

PMID:21873635

RGD
GO_Central

RGD:2311420, RGD:13792537

NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279

Ccdc88a

coiled coil domain containing 88A

involved_in

(PMID:21954290)

PMID:21954290

NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368

Clspn

claspin

involved_in

PMID:21873635
(PMID:16885022)

PMID:16885022 PMID:21873635

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

Dlg1

discs large MAGUK scaffold protein 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:3697750|PMID:17187070)

PMID:17187070

GO_REF:0000107 MGI:3697750

NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689

dopamine receptor D2

RGD

NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875

Ect2

epithelial cell transforming 2

involved_in

(PMID:15254234)

PMID:15254234

NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911

Emp2

epithelial membrane protein 2

involved_in

(PMID:21637765)
GO_REF:0000024

PMID:21637765

GO_REF:0000024

NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733

HNF1 homeobox A

RGD

NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104

Insr

insulin receptor

involved_in

(PMID:9819385)

PMID:9819385

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

Itgb3

integrin subunit beta 3

involved_in

(PMID:10022831)
GO_REF:0000107

PMID:10022831

GO_REF:0000107

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

Kif14

kinesin family member 14

involved_in

(PMID:24784001)

PMID:24784001

NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164

Ppp2r3c

protein phosphatase 2, regulatory subunit B'', gamma

acts_upstream_of_or_within
involved_in

MGI:3759678 (MGI:3589325|PMID:16129705)
GO_REF:0000107

PMID:16129705

GO_REF:0000107 MGI:3589325

NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491

Prkcd

protein kinase C, delta

involved_in

(PMID:10713049)
GO_REF:0000107

PMID:10713049

GO_REF:0000107

NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352

Prnp

prion protein

involved_in

ComplexPortal:CPX-1134 (MGI:5882868|PMID:23386614)

PMID:23386614

MGI:5882868

NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937

Ripk3

receptor-interacting serine-threonine kinase 3

involved_in

(PMID:22817896)
GO_REF:0000107
GO_REF:0000024

PMID:22817896

GO_REF:0000024 GO_REF:0000107

NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121

Sesn2

sestrin 2

acts_upstream_of_or_within

(MGI:6392416|PMID:31915252)

PMID:31915252

MGI:6392416

NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260

Slc11a1

solute carrier family 11 member 1

acts_upstream_of_or_within
involved_in

MGI:1857755 (MGI:64652|PMID:8301134)
GO_REF:0000107

PMID:8301134

GO_REF:0000107 MGI:64652

NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101

Stk11

serine/threonine kinase 11

involved_in
acts_upstream_of_or_within

ISS
IBA
ISO

PMID:15731909
PMID:21873635
(PMID:18854309)
(PMID:15731909), (PMID:19892943)
(MGI:3836081|PMID:18854309)

PMID:15731909 PMID:18854309 PMID:19892943 PMID:15731909 PMID:21873635

MGI:3836081, RGD:13702324, RGD:13792537

NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315

Strada

STE20 related adaptor alpha

involved_in
acts_upstream_of_or_within

IDA
IEA
IBA
ISO

PMID:14511394
GO_REF:0000107
PMID:21873635
(PMID:12805220), (PMID:19892943)
(MGI:3836081|PMID:18854309)

PMID:12805220 PMID:18854309 PMID:19892943 PMID:14511394 PMID:21873635

GO_REF:0000107 MGI:3836081, RGD:1600691, RGD:13792537

NCBI chr10:91,094,849...91,123,890
Ensembl chr10:91,094,687...91,123,830

Stradb

STE20 related adaptor beta

involved_in

(PMID:14517248)
PMID:21873635

PMID:14517248 PMID:21873635

NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084

Tgfb2

transforming growth factor, beta 2

involved_in

PMID:17192487 PMID:17960115

(PMID:17192487), (PMID:17960115)
GO_REF:0000024

RGD
AgBase

GO_REF:0000024

NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405

Tom1l1

target of myb1 like 1 membrane trafficking protein

involved_in

(PMID:16479011)
GO_REF:0000107

PMID:16479011

GO_REF:0000107

NCBI chr10:75,464,577...75,508,304
Ensembl chr10:75,464,577...75,508,250

Tpx2

TPX2, microtubule nucleation factor

involved_in

(PMID:14580337), (PMID:19801554)

PMID:14580337 PMID:19801554

NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468

Traf6

TNF receptor associated factor 6

involved_in

(PMID:17135271)

PMID:17135271

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

Vegfa

vascular endothelial growth factor A

involved_in

(PMID:18059339), (PMID:20497126)
GO_REF:0000107

PMID:18059339 PMID:20497126

GO_REF:0000107

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Wnk4

WNK lysine deficient protein kinase 4

involved_in

(MGI:5892167|PMID:28096417)

PMID:28096417

MGI:5892167

NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829

activation of protein kinase B activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adra2a

adrenoceptor alpha 2A

involved_in

(PMID:17215105)

PMID:17215105

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Adra2b

adrenoceptor alpha 2B

involved_in

(PMID:17215105)

PMID:17215105

NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355

Adra2c

adrenoceptor alpha 2C

involved_in

(PMID:17215105)

PMID:17215105

NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846

Ang

angiogenin

involved_in

(PMID:17125737)

PMID:17125737

NCBI chr15:24,317,733...24,323,361

Ccdc88a

coiled coil domain containing 88A

involved_in

(MGI:3581096|PMID:15753085)

PMID:15753085

MGI:3581096

NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368

Dynap

dynactin associated protein

involved_in

(PMID:20978158)

PMID:20978158

NCBI chr18:63,885,164...63,909,464
Ensembl chr18:63,886,448...63,913,232

Dynapl1

dynactin associated protein-like 1

involved_in

PMID:21873635

GO_Central

NCBI chr18:63,865,136...63,868,338
Ensembl chr18:63,865,133...63,868,338

Fgf1

fibroblast growth factor 1

involved_in

GO_REF:0000024
(PMID:18441324)

PMID:18441324

GO_REF:0000024

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

Gas6

growth arrest specific 6

involved_in

PMID:18374201

UniProt

PMID:18374201

RGD:8554638

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

Igf1

insulin-like growth factor 1

involved_in

(PMID:22351760)
GO_REF:0000107

PMID:22351760

GO_REF:0000107

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

Il18

interleukin 18

involved_in

(PMID:21321938)
GO_REF:0000107

PMID:21321938

GO_REF:0000107

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Ins2

insulin 2

involved_in

(PMID:8702995)

PMID:8702995

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

Insr

insulin receptor

involved_in

(PMID:7556070)

PMID:7556070

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

Itgb1bp1

integrin subunit beta 1 binding protein 1

involved_in

(PMID:20616313)

PMID:20616313

NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037

Mir21

microRNA 21

involved_in

(PMID:22879939)

PMID:22879939

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

Mt3

metallothionein 3

involved_in

(PMID:18295594)
GO_REF:0000024

PMID:18295594

GO_REF:0000024

NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158

Notch2

notch receptor 2

acts_upstream_of_or_within
involved_in

(MGI:6876976|PMID:34635817)
GO_REF:0000107

PMID:34635817

GO_REF:0000107 MGI:6876976

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

Nrg1

neuregulin 1

involved_in

(PMID:20682778)
GO_REF:0000107
GO_REF:0000024

PMID:20682778

GO_REF:0000024 GO_REF:0000107

NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884

Ntf3

neurotrophin 3

involved_in
acts_upstream_of

GO_REF:0000107
(PMID:23027130)

GO_REF:0000107

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

Ntrk3

neurotrophic receptor tyrosine kinase 3

acts_upstream_of
involved_in

(PMID:23027130)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

Osbpl8

oxysterol binding protein-like 8

involved_in

(MGI:5644010|PMID:23812417)

PMID:23812417

MGI:5644010

NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888

Pdgfb

platelet derived growth factor subunit B

involved_in

GO_REF:0000107

Ensembl

GO_REF:0000107

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

Pdpk1

3-phosphoinositide dependent protein kinase-1

involved_in

(PMID:9368760)
GO_REF:0000107

PMID:9368760

GO_REF:0000107

NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623

peptidylprolyl isomerase A

involved_in

GO_REF:0000024
(PMID:23180369)

PMID:23180369

GO_REF:0000024

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

peptidylprolyl isomerase A (cyclophilin A)-like 4D

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310

Prkcz

protein kinase C, zeta

in hepatocytes

RGD

PMID:15007074

RGD:1642700

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Slc1a1

solute carrier family 1 member 1

involved_in

(MGI:6478088|PMID:23827345)

PMID:23827345

MGI:6478088

NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402

Tcl1a

Tcl1 family Akt coactivator A

involved_in

(MGI:6377804|PMID:28262547)

PMID:28262547

MGI:6377804

NCBI chr 6:124,125,032...124,131,025
Ensembl chr 6:124,125,032...124,131,025

Wnt5a

Wnt family member 5A

acts_upstream_of
involved_in

(PMID:20034610)
GO_REF:0000107

PMID:20034610

GO_REF:0000107

NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234

activation of protein kinase C activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abl1

ABL proto-oncogene 1, non-receptor tyrosine kinase

involved_in

(PMID:10713049)

PMID:10713049

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

Cd86

CD86 molecule

involved_in

(MGI:5461234|PMID:23241883)

PMID:23241883

MGI:5461234

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

Lep

leptin

involved_in

IBA
ISO
ISS

PMID:21873635
(PMID:24340098)
GO_REF:0000024

PMID:24340098 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

Phb1

prohibitin 1

involved_in

GO_REF:0000024
(MGI:5461234|PMID:23241883)

PMID:23241883

GO_REF:0000024 MGI:5461234

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

Phb2

prohibitin 2

involved_in

ISO
ISS
IEA

(MGI:5461234|PMID:23241883)
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

PMID:23241883

GO_REF:0000024 GO_REF:0000107 MGI:5461234

NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272

activation of transmembrane receptor protein tyrosine kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Angpt1

angiopoietin 1

involved_in

GO_REF:0000107
(PMID:19424712)

PMID:19424712

GO_REF:0000107

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

Chrna3

cholinergic receptor nicotinic alpha 3 subunit

acts_upstream_of_or_within

MGI:2155602 (MGI:3590443|PMID:16162937)

PMID:16162937

MGI:3590443

NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165

Nrg1

neuregulin 1

involved_in

(PMID:9553078)
PMID:21873635

PMID:9553078 PMID:21873635

NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884

Pdgfc

platelet derived growth factor C

acts_upstream_of_or_within

(MGI:1858279|PMID:10806482)

PMID:10806482

MGI:1858279

NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433

Prlr

prolactin receptor

involved_in

(PMID:10585417)
GO_REF:0000107

PMID:10585417

GO_REF:0000107

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

negative regulation of activation of Janus kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cd300a

Cd300a molecule

involved_in

(PMID:16254138)

PMID:16254138

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

Hnf4a

hepatocyte nuclear factor 4, alpha

RGD

PMID:16584384

RGD:1625011

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

negative regulation of brain-derived neurotrophic factor-activated receptor activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fam72a

family with sequence similarity 72, member A

acts_upstream_of_or_within

PMID:19755123

MGI

PMID:19755123

RGD:8553945

NCBI chr13:42,968,409...42,978,976
Ensembl chr13:42,967,578...42,984,208

negative regulation of cAMP-dependent protein kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pkia

cAMP-dependent protein kinase inhibitor alpha

involved_in
acts_upstream_of_or_within

PMID:21873635
(PMID:7905001)
(PMID:21812984)

PMID:7905001 PMID:21812984 PMID:21873635

NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282

Pkib

cAMP-dependent protein kinase inhibitor beta

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3793555|PMID:7905001)

PMID:7905001 PMID:21873635

MGI:3793555, RGD:13792537

NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187

Pkig

cAMP-dependent protein kinase inhibitor gamma

involved_in

PMID:21873635

GO_Central

NCBI chr 3:152,330,486...152,398,085
Ensembl chr 3:152,366,041...152,398,082

Prkar1a

protein kinase cAMP-dependent type I regulatory subunit alpha

involved_in

(PMID:21812984)
GO_REF:0000107

PMID:21812984

GO_REF:0000107

NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041

Prkar1b

protein kinase cAMP-dependent type I regulatory subunit beta

involved_in

(PMID:21812984)

PMID:21812984

NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942

Prkar2a

protein kinase cAMP-dependent type II regulatory subunit alpha

involved_in

IEA
IBA
ISO

GO_REF:0000107
PMID:21873635
(PMID:22674394)
(PMID:21812984)

PMID:21812984 PMID:22674394 PMID:21873635

GO_REF:0000107, RGD:13792537

NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628

Prkar2b

protein kinase cAMP-dependent type II regulatory subunit beta

involved_in

(PMID:21812984)
PMID:21873635

PMID:21812984 PMID:21873635

NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933

sirtuin 1

involved_in

(PMID:20203304)
GO_REF:0000107

PMID:20203304

GO_REF:0000107

NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260

negative regulation of cyclin-dependent protein kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cdkn1a

cyclin-dependent kinase inhibitor 1A

involved_in

(PMID:8876165)

PMID:8876165

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

Cdkn1b

cyclin-dependent kinase inhibitor 1B

involved_in

(PMID:8684460)

PMID:8684460

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

Cdkn1c

cyclin-dependent kinase inhibitor 1C

involved_in

(PMID:11746698)

PMID:11746698

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

negative regulation of cyclin-dependent protein serine/threonine kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Apc

APC regulator of WNT signaling pathway

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(PMID:8521819)

Ensembl
UniProt
RGD

PMID:8521819

GO_REF:0000024 GO_REF:0000107

NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696

Casp3

caspase 3

acts_upstream_of_or_within

MGI:2178778 (MGI:2677082|PMID:12970760)

PMID:12970760

MGI:2677082

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

Cdk5rap1

CDK5 regulatory subunit associated protein 1

involved_in

ISO
ISS
IBA

(PMID:11882646)
GO_REF:0000024
PMID:21873635

PMID:11882646 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677

Cdk5rap2

CDK5 regulatory subunit associated protein 2

RGD

PMID:10721722

RGD:632478

NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782

CDK5 regulatory subunit associated protein 3

RGD

PMID:10721722

RGD:632478

NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590

Cdkn1a

cyclin-dependent kinase inhibitor 1A

acts_upstream_of_or_within
involved_in

(MGI:2183076|PMID:12130539)
PMID:21873635

PMID:12130539 PMID:21873635

MGI:2183076, RGD:13792537

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

Cdkn1b

cyclin-dependent kinase inhibitor 1B

involved_in
acts_upstream_of_or_within

IMP
IBA
ISO

PMID:21873635
(MGI:2183076|PMID:12130539)
(PMID:28666995)

PMID:12130539 PMID:28666995 PMID:22584582 PMID:21873635

MGI:2183076, RGD:10045364, RGD:13792537

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

Cdkn1c

cyclin-dependent kinase inhibitor 1C

involved_in

PMID:21873635

GO_Central

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

Cdkn2a

cyclin-dependent kinase inhibitor 2A

acts_upstream_of_or_within
involved_in

(MGI:2183076|PMID:12130539)
(PMID:7739547)
(PMID:8259215)

PMID:7739547 PMID:8259215 PMID:12130539

MGI:2183076

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Cdkn2c

cyclin-dependent kinase inhibitor 2C

acts_upstream_of_or_within

(MGI:72259|PMID:7739547)

PMID:7739547

MGI:72259

NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278

Fbxo7

F-box protein 7

acts_upstream_of_or_within

(MGI:5317390|PMID:21652635)

PMID:21652635

MGI:5317390

NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530

Hexim1

HEXIM P-TEFb complex subunit 1

involved_in

IBA
ISS
ISO

PMID:21873635
GO_REF:0000024
(PMID:14580347)

PMID:14580347 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189

Hexim2

HEXIM P-TEFb complex subunit 2

involved_in

PMID:21873635
(PMID:15713662)

PMID:15713662 PMID:21873635

NCBI chr10:88,077,870...88,084,776
Ensembl chr10:88,079,014...88,084,775

Hhex

hematopoietically expressed homeobox

involved_in

(PMID:12554669)

PMID:12554669

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

Inca1

inhibitor of CDK, cyclin A1 interacting protein 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(PMID:21540187)
MGI:5292392 (MGI:5286822|PMID:21540187)

PMID:21540187 PMID:21873635

MGI:5286822, RGD:13792537

NCBI chr10:55,401,982...55,414,364
Ensembl chr10:55,401,982...55,414,114

Kat2b

lysine acetyltransferase 2B

involved_in

(MGI:4410401|PMID:19773423)

PMID:19773423

MGI:4410401

NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064

Lats1

large tumor suppressor kinase 1

involved_in

(PMID:9988268)

PMID:9988268

NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640

Lats2

large tumor suppressor kinase 2

involved_in

(PMID:12853976)

PMID:12853976

NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220

Men1

menin 1

involved_in

(PMID:15640349)
GO_REF:0000107

PMID:15640349

GO_REF:0000107

NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871

Mir103a1

microRNA 103a-1

involved_in

(PMID:27343180)

NCBI chr10:20,244,412...20,244,497
Ensembl chr10:20,244,412...20,244,497

Mir103a2

microRNA 103a-2

involved_in

(PMID:27343180)

NCBI chr 3:118,510,194...118,510,279
Ensembl chr 3:118,510,194...118,510,279

Mir711

microRNA 711

involved_in

(PMID:26735582)

PMID:26735582

NCBI chr 8:109,621,975...109,622,042
Ensembl chr 8:109,621,975...109,622,042

Myocd

myocardin

involved_in

(PMID:18451334)
GO_REF:0000107

PMID:18451334

GO_REF:0000107

NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627

Nr2f2

nuclear receptor subfamily 2, group F, member 2

involved_in

(PMID:19210544)

PMID:19210544

NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031

Plk1

polo-like kinase 1

involved_in

GO_REF:0000107
(PMID:21041660)

PMID:21041660

GO_REF:0000107

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

Pten

phosphatase and tensin homolog

involved_in

(PMID:21241890)

PMID:21241890

NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838

Tfap4

transcription factor AP-4

involved_in

(PMID:18818310)

PMID:18818310

NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386

Tnfaip3

TNF alpha induced protein 3

involved_in

(MGI:4943408|PMID:15962316)

PMID:15962316

MGI:4943408

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

Wee2

WEE2 oocyte meiosis inhibiting kinase

involved_in

(MGI:4948986|PMID:21454751)

PMID:21454751

MGI:4948986

NCBI chr 4:69,239,043...69,261,576
Ensembl chr 4:69,239,299...69,261,093

negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dnajc3

DnaJ heat shock protein family (Hsp40) member C3

involved_in

(PMID:22064321)
(MGI:5617428|PMID:25329545)
GO_REF:0000024

PMID:22064321 PMID:25329545

GO_REF:0000024 MGI:5617428

NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181

Nck1

NCK adaptor protein 1

involved_in

(PMID:14676213), (PMID:16835242)
PMID:21873635
UniProtKB:O55033 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)

PMID:14676213 PMID:16835242 PMID:21873635

MGI:5613475 MGI:5613478, RGD:13792537

NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300

Nck2

NCK adaptor protein 2

involved_in

(PMID:16835242)
PMID:21873635
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)

PMID:14676213 PMID:16835242 PMID:21873635

MGI:5613475 MGI:5613478, RGD:13792537

NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307

protein phosphatase 1, regulatory subunit 15A

involved_in

(MGI:5613475|PMID:16835242)

PMID:16835242

MGI:5613475

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

Ppp1r15b

protein phosphatase 1, regulatory subunit 15B

involved_in

(MGI:5613475|PMID:16835242)

PMID:16835242

MGI:5613475

NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737

Tmed2

transmembrane p24 trafficking protein 2

acts_upstream_of_or_within
involved_in

MGI:4456438 (MGI:5914333|PMID:28797121)
GO_REF:0000107

PMID:28797121

GO_REF:0000107 MGI:5914333

NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903

negative regulation of epidermal growth factor-activated receptor activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cbl

Cbl proto-oncogene

involved_in

PMID:21873635

GO_Central

NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176

Cblb

Cbl proto-oncogene B

involved_in

PMID:21873635

GO_Central

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

Cblc

Cbl proto-oncogene C

involved_in

(PMID:10362357)
PMID:21873635

PMID:10362357 PMID:21873635

NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755

Chmp6

charged multivesicular body protein 6

involved_in

(PMID:16973552)

PMID:16973552

NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640

Errfi1

ERBB receptor feedback inhibitor 1

involved_in

ISS
IEA
ISO
IDA

GO_REF:0000024
GO_REF:0000107
(MGI:3629275|PMID:16648858)
PMID:17599051
(PMID:18046415)

PMID:16648858 PMID:18046415 PMID:17599051

GO_REF:0000024 GO_REF:0000107 MGI:3629275, RGD:8553726

NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282

Gprc5a

G protein-coupled receptor, class C, group 5, member A

involved_in

(MGI:5635952|PMID:25744720)

PMID:25744720

MGI:5635952

NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260

Psen1

presenilin 1

involved_in

(MGI:4887523|PMID:20208556)

PMID:20208556

MGI:4887523

NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650

Psen2

presenilin 2

involved_in

(MGI:4887523|PMID:20208556)

PMID:20208556

MGI:4887523

NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174

Socs4

suppressor of cytokine signaling 4

involved_in

(PMID:15590694)

PMID:15590694

NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494

Socs5

suppressor of cytokine signaling 5

involved_in

(PMID:15590694)

PMID:15590694

NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834

Tsg101

tumor susceptibility 101

involved_in

(PMID:16973552)
GO_REF:0000107

PMID:16973552

GO_REF:0000107

NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554

Vps25

vacuolar protein sorting 25 homolog

involved_in

(PMID:16973552)

PMID:16973552

NCBI chr10:86,196,062...86,201,606
Ensembl chr10:86,188,812...86,231,829

Zfyve28

zinc finger FYVE-type containing 28

involved_in

(PMID:19460345)
PMID:21873635

PMID:19460345 PMID:21873635

NCBI chr14:76,468,424...76,554,039
Ensembl chr14:76,468,424...76,554,039

Zgpat

zinc finger CCCH-type and G-patch domain containing

involved_in

(PMID:19644445)
GO_REF:0000024

PMID:19644445

GO_REF:0000024

NCBI chr 3:168,473,836...168,490,380
Ensembl chr 3:168,473,981...168,490,380

negative regulation of histone acetylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Anp32a

acidic nuclear phosphoprotein 32 family member A

RGD

PMID:19136565

RGD:10401132

NCBI chr 8:62,829,125...62,864,469
Ensembl chr 8:62,827,456...62,865,443

Brca1

BRCA1, DNA repair associated

involved_in

IEA
ISO
IBA

GO_REF:0000107
(MGI:5009779|PMID:20820192)
PMID:21873635

PMID:20820192 PMID:21873635

GO_REF:0000107 MGI:5009779, RGD:13792537

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

Ctbp1

C-terminal binding protein 1

involved_in

(PMID:21102443)

PMID:21102443

NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821

Thap7

THAP domain containing 7

involved_in

(PMID:16195249)

PMID:16195249

NCBI chr11:83,482,958...83,486,136
Ensembl chr11:83,483,037...83,486,436

Twist1

twist family bHLH transcription factor 1

involved_in

(MGI:3843109|PMID:19345188)

PMID:19345188

MGI:3843109

NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653

negative regulation of histone deacetylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Foxp3

forkhead box P3

involved_in

UniProtKB:P56524 (PMID:19276356)

PMID:19276356

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

negative regulation of histone H2A K63-linked ubiquitination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Otub1

OTU deubiquitinase, ubiquitin aldehyde binding 1

involved_in

PMID:21873635

GO_Central

NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483

Otub2

OTU deubiquitinase, ubiquitin aldehyde binding 2

involved_in

PMID:21873635

GO_Central

NCBI chr 6:122,545,029...122,563,651
Ensembl chr 6:122,545,061...122,563,644

Trip12

thyroid hormone receptor interactor 12

involved_in

PMID:21873635

GO_Central

NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403

Ubr5

ubiquitin protein ligase E3 component n-recognin 5

involved_in

PMID:21873635

GO_Central

NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903

negative regulation of histone H3-K4 methylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Brca1

BRCA1, DNA repair associated

involved_in

GO_REF:0000107
(MGI:5009779|PMID:20820192)

PMID:20820192

GO_REF:0000107 MGI:5009779

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

Kdm1a

lysine demethylase 1A

involved_in

(MGI:4461095|PMID:20123967)

PMID:20123967

MGI:4461095

NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319

negative regulation of histone H3-K9 acetylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hdac8

histone deacetylase 8

RGD

PMID:25019367

RGD:13208813

NCBI chr X:67,385,288...67,593,014
Ensembl chr X:67,385,289...67,592,923

negative regulation of histone H3-K9 methylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Brca1

BRCA1, DNA repair associated

involved_in

(PMID:20820192)
GO_REF:0000107
(MGI:5009779|PMID:20820192)

PMID:20820192

GO_REF:0000107 MGI:5009779

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

Kdm1a

lysine demethylase 1A

involved_in

(MGI:4461095|PMID:20123967)

PMID:20123967

MGI:4461095

NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319

negative regulation of histone H3-K9 trimethylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sirtuin 1

involved_in

(MGI:5810254|PMID:25526086)
GO_REF:0000107

PMID:25526086

GO_REF:0000107 MGI:5810254

NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260

negative regulation of histone H4 acetylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ctbp1

C-terminal binding protein 1

involved_in

(PMID:21102443)
GO_REF:0000107

PMID:21102443

GO_REF:0000107

NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821

negative regulation of I-kappaB phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mir27b

microRNA 27b

acts_upstream_of_or_within

UniProtKB:P01375 (PMID:31124343)

PMID:31124343

NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529

Sirpa

signal-regulatory protein alpha

involved_in

(MGI:3760575|PMID:17954568)

PMID:17954568

MGI:3760575

NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098

negative regulation of JUN kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aida

axin interactor, dorsalization associated

acts_upstream_of_or_within

(MGI:3799599|PMID:17681137)
(PMID:17681137)

PMID:17681137

MGI:3799599

NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920

Dnaja1

DnaJ heat shock protein family (Hsp40) member A1

involved_in

(PMID:24512202)
GO_REF:0000024

PMID:24512202

GO_REF:0000024

NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967

Dusp10

dual specificity phosphatase 10

involved_in
acts_upstream_of_or_within

(PMID:10391943)
MGI:3052343 (MGI:3051749|PMID:15306813)
PMID:21873635

PMID:10391943 PMID:15306813 PMID:21873635

MGI:3051749, RGD:13792537

NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716

Dusp16

dual specificity phosphatase 16

involved_in

(PMID:11489891)

PMID:11489891

NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980

Dusp19

dual specificity phosphatase 19

involved_in

(MGI:2182169|PMID:11959862)

PMID:11959862

MGI:2182169

NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534

Gstp1

glutathione S-transferase pi 1

involved_in

PMID:10945608 PMID:12646564 PMID:16023107 PMID:16636664

GO_REF:0000024
(MGI:3721484|PMID:12646564), (MGI:5009198|PMID:10945608), (MGI:5009411|PMID:16023107)
(PMID:16636664)

BHF-UCL
RGD

GO_REF:0000024 MGI:3721484 MGI:5009198 MGI:5009411

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

Hipk3

homeodomain interacting protein kinase 3

involved_in

(MGI:1913166|PMID:11034606)

PMID:11034606

MGI:1913166

NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759

Mapk8ip1

mitogen-activated protein kinase 8 interacting protein 1

involved_in

PMID:12064607 PMID:21076496

PMID:21076496

RGD
UniProt

RGD:1299562, RGD:13673827

NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884

Nppa

natriuretic peptide A

involved_in

(PMID:22399583)
GO_REF:0000107

PMID:22399583

GO_REF:0000107

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

Pdcd4

programmed cell death 4

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

Ptpn22

protein tyrosine phosphatase, non-receptor type 22

involved_in

(PMID:23991106)

PMID:23991106

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

Serpinb3

serpin family B member 3

involved_in

(PMID:21383048)

PMID:21383048

NCBI chr13:23,274,120...23,280,082
Ensembl chr13:23,274,484...23,313,682

Sfrp1

secreted frizzled-related protein 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:108078|MGI:1860298 (MGI:3839161|PMID:19300477)

PMID:19300477

GO_REF:0000107 MGI:3839161

NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286

Sfrp2

secreted frizzled-related protein 2

acts_upstream_of_or_within

MGI:1860298|MGI:892014 (MGI:3839161|PMID:19300477)

PMID:19300477

MGI:3839161

NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063

Sfrp5

secreted frizzled-related protein 5

acts_upstream_of_or_within

MGI:108078|MGI:892014 (MGI:3839161|PMID:19300477)

PMID:19300477

MGI:3839161

NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224

Tp73

tumor protein p73

acts_upstream_of_or_within

(MGI:3574697|PMID:15483136)

PMID:15483136

MGI:3574697

NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128

negative regulation of MAP kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adipoq

adiponectin, C1Q and collagen domain containing

involved_in

GO_REF:0000024
(MGI:4943654|PMID:19460854)

PMID:19460854

GO_REF:0000024 MGI:4943654

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

Agt

angiotensinogen

involved_in

(PMID:28283184)
GO_REF:0000107

PMID:28283184

GO_REF:0000107

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

Apoe

apolipoprotein E

involved_in

(PMID:9685360)
GO_REF:0000107

PMID:9685360

GO_REF:0000107

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

Bmp2

bone morphogenetic protein 2

acts_upstream_of
involved_in

(PMID:18382765)
GO_REF:0000107

PMID:18382765

GO_REF:0000107

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

Bmp4

bone morphogenetic protein 4

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:17244894)

PMID:17244894

GO_REF:0000024 GO_REF:0000107

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

Bmp7

bone morphogenetic protein 7

involved_in

(PMID:17244894)

PMID:17244894

NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788

Cav1

caveolin 1

acts_upstream_of_or_within
involved_in

MGI:2180364 (MGI:3703676|PMID:12388746)
GO_REF:0000107

PMID:12388746

GO_REF:0000107 MGI:3703676

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

Cav3

caveolin 3

involved_in

(PMID:12847114)

PMID:12847114

NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137

Cblc

Cbl proto-oncogene C

involved_in

(PMID:10362357)

PMID:10362357

NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755

Cd300a

Cd300a molecule

involved_in

(PMID:16254138)

PMID:16254138

NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674

CDK5 regulatory subunit associated protein 3

involved_in

(PMID:21283629)
GO_REF:0000107
GO_REF:0000024

PMID:21283629

GO_REF:0000024 GO_REF:0000107

NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590

Dab2ip

DAB2 interacting protein

involved_in

(PMID:12813029), (PMID:20154697)
GO_REF:0000107
GO_REF:0000024

PMID:12813029 PMID:20154697

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280

Dusp1

dual specificity phosphatase 1

involved_in

(PMID:7593328)
GO_REF:0000024

PMID:7593328

GO_REF:0000024

NCBI chr10:16,680,489...16,683,276

Dusp7

dual specificity phosphatase 7

involved_in

(PMID:9788880)

PMID:9788880

NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404

Fem1a

fem-1 homolog A

acts_upstream_of_or_within

(MGI:3790904|PMID:18270204)

PMID:18270204

MGI:3790904

NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628

Gba

glucosylceramidase beta

involved_in

(PMID:19279008)

PMID:19279008

NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263

Gsk3b

glycogen synthase kinase 3 beta

RGD

PMID:17182785

RGD:2301767

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

Gstp1

glutathione S-transferase pi 1

involved_in

(PMID:11408560)

PMID:11408560

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

Hmgcr

3-hydroxy-3-methylglutaryl-CoA reductase

acts_upstream_of_or_within
involved_in

MGI:97306 (MGI:3610622|PMID:16271875), (MGI:3610917|PMID:12409258)
GO_REF:0000107

PMID:12409258 PMID:16271875

GO_REF:0000107 MGI:3610622 MGI:3610917

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

Hyal2

hyaluronidase 2

involved_in

(PMID:12676986)
GO_REF:0000107
GO_REF:0000024

PMID:12676986

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850

Il1b

interleukin 1 beta

involved_in

(MGI:3828398|PMID:16865359)
GO_REF:0000107

PMID:16865359

GO_REF:0000107 MGI:3828398

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

inositol polyphosphate-5-phosphatase K

involved_in

(PMID:12556481)

PMID:12556481

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

Inppl1

inositol polyphosphate phosphatase-like 1

RGD

PMID:12933696

RGD:1626126

NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500

Irak3

interleukin-1 receptor-associated kinase 3

involved_in

PMID:21873635
(MGI:3843426|PMID:17379480)
(PMID:17379480)

PMID:17379480 PMID:21873635

MGI:3843426, RGD:13792537

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

Kng2

kininogen 2

in ConA- or PHA-stimulated Jurkat cells

RGD

PMID:16140359

RGD:1600541

NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971

Lax1

lymphocyte transmembrane adaptor 1

involved_in

(PMID:12359715)

PMID:12359715

NCBI chr13:45,134,825...45,145,381
Ensembl chr13:45,134,834...45,145,381

Lyn

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000024
(MGI:894972|PMID:9252121)

PMID:9252121

GO_REF:0000024 MGI:894972

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Mapk7

mitogen-activated protein kinase 7

acts_upstream_of_or_within

(MGI:1933463|PMID:11139578)
(MGI:2135469|PMID:11381262)

PMID:11139578 PMID:11381262

MGI:1933463 MGI:2135469

NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267

Mir218-2

microRNA 218-2

involved_in

(PMID:21385766)

PMID:10620616 PMID:11297510 PMID:12409258 PMID:16271875

PMID:21385766

NCBI chr10:20,068,451...20,068,560
Ensembl chr10:20,068,451...20,068,560

Nf1

neurofibromin 1

involved_in
acts_upstream_of_or_within

ISS
ISO
IEA

HGNC-UCL
RGD
Ensembl

GO_REF:0000024 GO_REF:0000107 MGI:1351242 MGI:1932841 MGI:3610622 MGI:3610917

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

Nup62

nucleoporin 62

involved_in

(MGI:3526674|PMID:11489947)

PMID:11489947

MGI:3526674

NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174

Paqr3

progestin and adipoQ receptor family member 3

acts_upstream_of_or_within

MGI:3757569 (MGI:3722998|PMID:17724343)
(PMID:17724343)

PMID:17724343

MGI:3722998

NCBI chr14:12,462,568...12,484,999
Ensembl chr14:12,462,563...12,479,994

Pik3cb

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

involved_in

GO_REF:0000107
(MGI:6444553|PMID:30496354)

PMID:30496354

GO_REF:0000107 MGI:6444553

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

Pparg

peroxisome proliferator-activated receptor gamma

acts_upstream_of_or_within

(PMID:18382765)

PMID:18382765

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

Prkcd

protein kinase C, delta

involved_in

(PMID:19279008)
GO_REF:0000107

PMID:19279008

GO_REF:0000107

NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352

Ptpn1

protein tyrosine phosphatase, non-receptor type 1

involved_in

(PMID:22045810)

PMID:22045810

NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504

Ptpn5

protein tyrosine phosphatase, non-receptor type 5

RGD

PMID:9857190

RGD:10044039

NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856074 (MGI:1095647|PMID:9254656), (MGI:82729|PMID:9064344)

PMID:9064344 PMID:9254656

GO_REF:0000107 MGI:1095647 MGI:82729

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Ptprj

protein tyrosine phosphatase, receptor type, J

involved_in

(PMID:19494114)
(MGI:4942250|PMID:12833140)
PMID:21873635

PMID:12833140 PMID:19494114 PMID:21873635

MGI:4942250, RGD:13792537

NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260

Rgs14

regulator of G-protein signaling 14

involved_in

GO_REF:0000024
(MGI:4834960|PMID:20837545)

PMID:20837545

GO_REF:0000024 MGI:4834960

NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104

Rgs2

regulator of G-protein signaling 2

involved_in

(MGI:3836877|PMID:19127022)

PMID:19127022

MGI:3836877

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

Sh2b3

SH2B adaptor protein 3

involved_in

GO_REF:0000107
(MGI:3510267|PMID:15337790)

PMID:15337790

GO_REF:0000107 MGI:3510267

NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616

Smpd1

sphingomyelin phosphodiesterase 1

involved_in

(PMID:19279008)

PMID:19279008

NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794

Sorl1

sortilin related receptor 1

involved_in

(MGI:3801250|PMID:18362153)

PMID:18362153

MGI:3801250

NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513

Spry1

sprouty RTK signaling antagonist 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3614383|PMID:16339969)

PMID:16339969 PMID:21873635

MGI:3614383, RGD:13792537

NCBI chr 2:120,557,276...120,561,918
Ensembl chr 2:120,556,706...120,566,189

Spry2

sprouty RTK signaling antagonist 2

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3614383|PMID:16339969)

PMID:16339969 PMID:21873635

MGI:3614383, RGD:13792537

NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009

Spry3

sprouty RTK signaling antagonist 3

involved_in

PMID:21873635

GO_Central

NCBI chr12:16,663,188...16,673,124
Ensembl chr12:16,663,389...16,672,531

Spry4

sprouty RTK signaling antagonist 4

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:3614383|PMID:16339969)

PMID:16339969 PMID:21873635

MGI:3614383, RGD:13792537

NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004

Stk38

serine/threonine kinase 38

involved_in

(PMID:17906693)

PMID:17906693

NCBI chr20:7,034,245...7,067,803
Ensembl chr20:7,034,242...7,068,198

Tsc2

TSC complex subunit 2

RGD

PMID:14612383

RGD:1580517

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

Uchl1

ubiquitin C-terminal hydrolase L1

involved_in

(PMID:19477270)

PMID:19477270

NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590

negative regulation of myosin-light-chain-phosphatase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ikbkb

inhibitor of nuclear factor kappa B kinase subunit beta

involved_in

(PMID:25816133)
GO_REF:0000107

GO_REF:0000107

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

Mprip

myosin phosphatase Rho interacting protein

RGD

PMID:17661354

RGD:9685557

NCBI chr10:44,453,929...44,569,442
Ensembl chr10:44,453,929...44,569,118

Nckap1l

NCK associated protein 1 like

involved_in

GO_REF:0000024
(PMID:16417406)

PMID:16417406

GO_REF:0000024

NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934

Rock1

Rho-associated coiled-coil containing protein kinase 1

involved_in

UniProtKB:O75116 (PMID:25816133)
GO_REF:0000107

GO_REF:0000107

NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571

Rock2

Rho-associated coiled-coil containing protein kinase 2

involved_in

GO_REF:0000107
UniProtKB:Q13464 (PMID:25816133)

GO_REF:0000107

NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031

Tnf

tumor necrosis factor

involved_in

(PMID:25816133)

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

negative regulation of N-terminal protein palmitoylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hhatl

hedgehog acyltransferase-like

involved_in

PMID:21873635
(MGI:3772109|PMID:18081866)

PMID:18081866 PMID:21873635

MGI:3772109, RGD:13792537

NCBI chr 8:121,447,001...121,454,070
Ensembl chr 8:121,447,002...121,454,001

negative regulation of non-membrane spanning protein tyrosine kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dusp22

dual specificity phosphatase 22

involved_in

(PMID:20018849)

PMID:20018849

NCBI chr17:33,780,980...33,831,540
Ensembl chr17:33,780,981...33,831,321

Mir138-1

microRNA 138-1

involved_in

(PMID:21444814)

PMID:21444814

NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064

Mir138-2

microRNA 138-2

involved_in

(PMID:21444814)

PMID:21444814

NCBI chr19:10,674,193...10,674,274
Ensembl chr19:10,674,193...10,674,274

negative regulation of pathway-restricted SMAD protein phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dkk1

dickkopf WNT signaling pathway inhibitor 1

involved_in

(PMID:20559569)

PMID:20559569

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

Emilin1

elastin microfibril interfacer 1

involved_in

(MGI:5605894|PMID:25056700)

PMID:25056700

MGI:5605894

NCBI chr 6:25,455,974...25,463,736
Ensembl chr 6:25,445,298...25,463,698

Eng

endoglin

involved_in

(PMID:18974388)

PMID:18974388

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

Grem1

gremlin 1, DAN family BMP antagonist

involved_in

(PMID:15539560)

PMID:15539560

NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082

Ldlrad4

low density lipoprotein receptor class A domain containing 4

involved_in

PMID:21873635
(PMID:24627487)

PMID:24627487 PMID:21873635

NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238

Lrp1

LDL receptor related protein 1

involved_in

(MGI:6434720|PMID:31023188)

PMID:31023188

MGI:6434720

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

Mirlet7g

microRNA let-7g

involved_in

(PMID:24291274)

PMID:24291274

NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388

Nog

noggin

involved_in

GO_REF:0000107
(MGI:3783944|PMID:17218603)
(PMID:15539560)

PMID:15539560 PMID:17218603

GO_REF:0000107 MGI:3783944

NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339

Pmepa1

prostate transmembrane protein, androgen induced 1

involved_in

PMID:21873635
(MGI:5582164|PMID:20129061)
(PMID:20129061), (PMID:24627487)

PMID:20129061 PMID:24627487 PMID:21873635

MGI:5582164, RGD:13792537

NCBI chr 3:162,011,884...162,060,137
Ensembl chr 3:162,012,751...162,060,454

Pparg

peroxisome proliferator-activated receptor gamma

involved_in

UniProtKB:P01137 (PMID:28467929), (PMID:31023188)

PMID:28467929 PMID:31023188

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

Smad6

SMAD family member 6

involved_in

(PMID:19047146), (PMID:9436979)

PMID:9436979 PMID:19047146

NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763

Smad7

SMAD family member 7

involved_in

(PMID:17438144)
GO_REF:0000107

PMID:17438144

GO_REF:0000107

NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765

Snx25

sorting nexin 25

involved_in

(PMID:21266196)

PMID:21266196

NCBI chr16:46,134,552...46,238,471
Ensembl chr16:46,125,804...46,238,440

Xbp1

X-box binding protein 1

involved_in

(PMID:26315405)

PMID:26315405

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

negative regulation of peptidyl-cysteine S-nitrosylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dmd

dystrophin

involved_in

(MGI:3837615|PMID:19198614), (MGI:4420848|PMID:20080623)

PMID:19198614 PMID:20080623

MGI:3837615 MGI:4420848

NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207

Mir132

microRNA 132

involved_in

(PMID:28089352)

NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796

Mir212

microRNA 212

involved_in

(PMID:28089352)

NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513

Ncoa7

nuclear receptor coactivator 7

acts_upstream_of_or_within

(MGI:5766554|PMID:26668325)

PMID:26668325

MGI:5766554

NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871

Oxr1

oxidation resistance 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:5766554|PMID:26668325)

PMID:26668325

GO_REF:0000107 MGI:5766554

NCBI chr 7:72,528,782...72,965,666
Ensembl chr 7:72,528,786...72,965,666

Snta1

syntrophin, alpha 1

involved_in

(PMID:18591664)

PMID:18591664

NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709

Tbc1d24

TBC1 domain family, member 24

acts_upstream_of_or_within

(MGI:5766554|PMID:26668325)

PMID:26668325

MGI:5766554

NCBI chr10:13,205,819...13,236,013
Ensembl chr10:13,209,895...13,236,050

negative regulation of peptidyl-lysine acetylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Hdac1

histone deacetylase 1

RGD

PMID:21465537

RGD:9590234

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

Hdac2

histone deacetylase 2

PMID:19486889 PMID:21465537

RGD

RGD:9590233, RGD:9590234

NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609

Hint2

histidine triad nucleotide binding protein 2

acts_upstream_of_or_within

MGI:5812015 (MGI:5788361|PMID:26767982)

PMID:26767982

MGI:5788361

NCBI chr 5:57,904,613...57,906,868
Ensembl chr 5:57,904,614...57,907,097

Klf15

KLF transcription factor 15

involved_in

(PMID:20375365)
(MGI:4880843|PMID:20375365)

PMID:20375365

MGI:4880843

NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374

sirtuin 1

involved_in

(PMID:20100829)
GO_REF:0000107

PMID:20100829

GO_REF:0000107

NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260

Sirt3

sirtuin 3

acts_upstream_of_or_within

MGI:3769234 (MGI:3768489|PMID:17923681)

PMID:17923681

MGI:3768489

NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808

negative regulation of peptidyl-lysine crotonylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cdyl

chromodomain Y-like

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:6103059|PMID:28803779)
(PMID:28803779)

PMID:28803779

GO_REF:0000024 GO_REF:0000107 MGI:6103059

NCBI chr17:28,982,009...29,204,345
Ensembl chr17:28,982,037...29,204,313

negative regulation of peptidyl-serine dephosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ppp1r16b

protein phosphatase 1, regulatory subunit 16B

involved_in

(PMID:25007873)

PMID:25007873

NCBI chr 3:147,323,652...147,419,658
Ensembl chr 3:147,324,126...147,418,937

Swap70

switching B-cell complex subunit SWAP70

involved_in

(MGI:5554982|PMID:23921380)

PMID:23921380

MGI:5554982

NCBI chr 1:164,267,588...164,328,796
Ensembl chr 1:164,267,609...164,328,794

Ywhae

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

involved_in

(PMID:11953308)

PMID:11953308

NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589

negative regulation of peptidyl-serine phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bak1

BCL2-antagonist/killer 1

acts_upstream_of_or_within

MGI:99702 (MGI:3527292|PMID:15613488)

PMID:15613488

MGI:3527292

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

Bax

BCL2 associated X, apoptosis regulator

acts_upstream_of_or_within

MGI:1097161 (MGI:3527292|PMID:15613488)

PMID:15613488

MGI:3527292

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

Bdkrb2

bradykinin receptor B2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857135 (MGI:3654719|PMID:16571598)

PMID:16571598

GO_REF:0000107 MGI:3654719

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

Cav1

caveolin 1

involved_in

(PMID:18081315)
GO_REF:0000107

PMID:18081315

GO_REF:0000107

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

Cnksr3

Cnksr family member 3

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:4457233|PMID:19567370)

PMID:19567370

GO_REF:0000024 GO_REF:0000107 MGI:4457233

NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635

Dkk1

dickkopf WNT signaling pathway inhibitor 1

involved_in

(PMID:20723538)

PMID:20723538

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

Dmd

dystrophin

involved_in

(MGI:5487906|PMID:23263329)

PMID:23263329

MGI:5487906

NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207

Dmtn

dematin actin binding protein

involved_in

(MGI:3803395|PMID:18505823)

PMID:18505823

MGI:3803395

NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601

Epm2a

EPM2A glucan phosphatase, laforin

acts_upstream_of_or_within
involved_in

MGI:2182627 (MGI:3826692|PMID:18824542)
GO_REF:0000107

PMID:18824542

GO_REF:0000107 MGI:3826692

NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555

Gpd1l1

glycerol-3-phosphate dehydrogenase 1 like 1

involved_in

(PMID:19666841)

PMID:19666841

NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723

Grk2

G protein-coupled receptor kinase 2

Akt1

RGD

PMID:26660861

RGD:13514041

NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582

Hgf

hepatocyte growth factor

acts_upstream_of_or_within
involved_in

(MGI:4849876|PMID:21072211)
GO_REF:0000107

PMID:21072211

GO_REF:0000107 MGI:4849876

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

Inpp5f

inositol polyphosphate-5-phosphatase F

involved_in

PMID:26908121

ParkinsonsUK-UCL

PMID:26908121

RGD:11059577

NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276

Inpp5j

inositol polyphosphate-5-phosphatase J

involved_in
acts_upstream_of_or_within

IBA
IEA
ISO

PMID:21873635
GO_REF:0000107
(MGI:3654813|PMID:16280363)

PMID:16280363 PMID:21873635

GO_REF:0000107 MGI:3654813, RGD:13792537

NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326

inositol polyphosphate-5-phosphatase K

involved_in
acts_upstream_of_or_within

(PMID:12556481)
(MGI:5294535|PMID:19250614)
MGI:3810936 (MGI:3810008|PMID:18573875)
PMID:21873635

PMID:12556481 PMID:18573875 PMID:19250614 PMID:21873635

MGI:3810008 MGI:5294535, RGD:13792537

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

Mir132

microRNA 132

involved_in

(PMID:28089352)

NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796

Mir212

microRNA 212

involved_in

(PMID:28089352)

NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513

Mir219a1

microRNA 219a-1

acts_upstream_of

(PMID:30556160)

PMID:30556160

NCBI chr20:4,829,687...4,829,796
Ensembl chr20:4,829,687...4,829,796

Mlxipl

MLX interacting protein-like

involved_in

(PMID:19995986)
GO_REF:0000107

PMID:19995986

GO_REF:0000107

NCBI chr12:21,542,964...21,577,120
Ensembl chr12:21,543,576...21,577,112

Nck1

NCK adaptor protein 1

involved_in

(PMID:14676213), (PMID:16835242)

PMID:14676213 PMID:16835242

NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300

Nck2

NCK adaptor protein 2

involved_in

(PMID:16835242)

PMID:16835242

NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307

Nos1

nitric oxide synthase 1

involved_in

PMID:19278978

BHF-UCL

PMID:19278978

RGD:10047220

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase

Akt1

RGD

PMID:21712532

RGD:9590189

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

Paqr3

progestin and adipoQ receptor family member 3

acts_upstream_of_or_within

(PMID:17724343)

PMID:17724343

NCBI chr14:12,462,568...12,484,999
Ensembl chr14:12,462,563...12,479,994

Pde4d

phosphodiesterase 4D

involved_in

(MGI:3690823|PMID:16213210)

PMID:16213210

MGI:3690823

NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884

Ppm1f

protein phosphatase, Mg2+/Mn2+ dependent, 1F

involved_in

(PMID:15140879)
GO_REF:0000024

PMID:15140879

GO_REF:0000024

NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340

Pten

phosphatase and tensin homolog

involved_in

(PMID:10918569)

PMID:10918569

NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838

Rack1

receptor for activated C kinase 1

involved_in

(PMID:20103773)

PMID:20103773

NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975

Rassf2

Ras association domain family member 2

acts_upstream_of_or_within
involved_in

(PMID:19962960)
GO_REF:0000107

PMID:19962960

GO_REF:0000107

NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431

Smad7

SMAD family member 7

involved_in

(PMID:18593713)
(MGI:5532916|PMID:18593713)
GO_REF:0000107

PMID:18593713

GO_REF:0000107 MGI:5532916

NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765

negative regulation of peptidyl-serine phosphorylation of STAT protein

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gadd45a

growth arrest and DNA-damage-inducible, alpha

involved_in

GO_REF:0000107
(MGI:6377865|PMID:23329839)
(PMID:23329839)

PMID:23329839

GO_REF:0000107 MGI:6377865

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

Ggnbp2

gametogenetin binding protein 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:4072637 (MGI:5779255|PMID:26764350)

PMID:26764350

GO_REF:0000107 MGI:5779255

NCBI chr10:69,711,527...69,743,134
Ensembl chr10:69,711,532...69,743,365

Pwp1

PWP1 homolog, endonuclein

acts_upstream_of_or_within

(MGI:5659778|PMID:25335925)

PMID:25335925

MGI:5659778

NCBI chr 7:17,982,730...17,998,728
Ensembl chr 7:17,982,235...17,998,731

negative regulation of peptidyl-threonine phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cadm4

cell adhesion molecule 4

involved_in

ISS
ISO
IEA

GO_REF:0000024
(MGI:6270911|PMID:23611113)
(PMID:23611113)
GO_REF:0000107

UniProt
RGD
Ensembl

PMID:23611113

GO_REF:0000024 GO_REF:0000107 MGI:6270911

NCBI chr 1:80,075,232...80,096,511
Ensembl chr 1:80,075,202...80,097,423

Dgkq

diacylglycerol kinase, theta

involved_in

UniProtKB:P01133 (PMID:22732145)

PMID:22732145

NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131

Dmtn

dematin actin binding protein

involved_in

(MGI:3803395|PMID:18505823)

PMID:18505823

MGI:3803395

NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601

Eif4g1

eukaryotic translation initiation factor 4 gamma 1

involved_in

(PMID:18426977)

PMID:18426977

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

Grk2

G protein-coupled receptor kinase 2

Akt1

RGD

PMID:26660861

RGD:13514041

NCBI chr 1:201,581,480...201,601,580
Ensembl chr 1:201,581,480...201,601,582

HNF1 homeobox A

RGD

NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104

inositol polyphosphate-5-phosphatase K

involved_in

(PMID:12556481)

PMID:12556481

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

Met

MET proto-oncogene, receptor tyrosine kinase

MAP2

RGD

PMID:18262389

RGD:2317458

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

Mir103a1

microRNA 103a-1

involved_in

(PMID:27343180)

NCBI chr10:20,244,412...20,244,497
Ensembl chr10:20,244,412...20,244,497

Mir103a2

microRNA 103a-2

involved_in

(PMID:27343180)

NCBI chr 3:118,510,194...118,510,279
Ensembl chr 3:118,510,194...118,510,279

Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase

Akt1

RGD

PMID:21712532

RGD:9590189

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

Pard3

par-3 family cell polarity regulator

involved_in

GO_REF:0000024
(MGI:5295137|PMID:21949390)

PMID:21949390

GO_REF:0000024 MGI:5295137

NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778

Ppef2

protein phosphatase with EF-hand domain 2

involved_in

(PMID:20674765)

PMID:20674765

NCBI chr14:15,797,435...15,831,614
Ensembl chr14:15,797,435...15,831,491

protein phosphatase 1, regulatory subunit 15A

Tsc2

RGD

PMID:21925170

RGD:9999170

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

Ppp2r5d

protein phosphatase 2, regulatory subunit B', delta

RGD

PMID:17301223

RGD:13515116

NCBI chr 9:14,270,364...14,300,396
Ensembl chr 9:14,268,745...14,300,400

Sirt2

sirtuin 2

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5295137|PMID:21949390)

PMID:21949390

GO_REF:0000024 GO_REF:0000107 MGI:5295137

NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975

Smad7

SMAD family member 7

involved_in

GO_REF:0000107
(MGI:5532916|PMID:18593713)
(PMID:18593713)

PMID:18593713

GO_REF:0000107 MGI:5532916

NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765

Spred1

sprouty-related, EVH1 domain containing 1

involved_in

(PMID:20736167)
(MGI:5318016|PMID:20736167)

PMID:20736167

MGI:5318016

NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718

Spred2

sprouty-related, EVH1 domain containing 2

involved_in

(PMID:20736167)
GO_REF:0000107
(MGI:5318016|PMID:20736167)

PMID:20736167

GO_REF:0000107 MGI:5318016

NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162

Spry2

sprouty RTK signaling antagonist 2

involved_in

(PMID:20736167)

PMID:20736167

NCBI chr15:82,692,312...82,697,408
Ensembl chr15:82,692,143...82,698,009

Ttc36

tetratricopeptide repeat domain 36

acts_upstream_of_or_within

MGI:5588394 (MGI:6362140|PMID:31537781)

PMID:31537781

MGI:6362140

NCBI chr 8:45,112,737...45,116,345

negative regulation of peptidyl-tyrosine autophosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cav1

caveolin 1

involved_in

(PMID:25006397)
GO_REF:0000107
(MGI:5607357|PMID:25017399)

PMID:25006397 PMID:25017399

GO_REF:0000107 MGI:5607357

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

negative regulation of peptidyl-tyrosine phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cadm4

cell adhesion molecule 4

involved_in

IEA
IBA
ISO
ISS

GO_REF:0000107
PMID:21873635
(MGI:6270911|PMID:23611113)
(PMID:23611113)
GO_REF:0000024

Ensembl
RGD
UniProt

PMID:23611113 PMID:21873635

GO_REF:0000024 GO_REF:0000107 MGI:6270911, RGD:13792537

NCBI chr 1:80,075,232...80,096,511
Ensembl chr 1:80,075,202...80,097,423

Dmtn

dematin actin binding protein

involved_in

(MGI:3803395|PMID:18505823)

PMID:18505823

MGI:3803395

NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601

Errfi1

ERBB receptor feedback inhibitor 1

involved_in

PMID:17599051

UniProt

PMID:17599051

RGD:8553726

NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282

Igf1

insulin-like growth factor 1

acts_upstream_of_or_within

MGI:2386329 (MGI:5433272|PMID:21677284)

PMID:21677284

MGI:5433272

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

interleukin 18

RGD

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

Lrrk1

leucine-rich repeat kinase 1

acts_upstream_of_or_within

MGI:5568128 (MGI:5564766|PMID:23526378)

PMID:23526378

MGI:5564766

NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734

Mir106b

microRNA 106b

involved_in

(PMID:27520374)

PMID:27520374

NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425

Ntf3

neurotrophin 3

involved_in

(PMID:23027130)
GO_REF:0000107

GO_REF:0000107

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

Pecam1

platelet and endothelial cell adhesion molecule 1

RGD

PMID:17662049

RGD:7240703

NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116

Prkcd

protein kinase C, delta

involved_in

(MGI:3843438|PMID:14583092)
GO_REF:0000107

PMID:14583092

GO_REF:0000107 MGI:3843438

NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352

Prkcz

protein kinase C, zeta

involved_in

(PMID:15069075)

PMID:15069075

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

Ptpn6

protein tyrosine phosphatase, non-receptor type 6

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856074 (MGI:1095647|PMID:9254656)
(PMID:19749791)

PMID:9254656 PMID:19749791

GO_REF:0000107 MGI:1095647

NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984

Ptprc

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within

(MGI:65996|PMID:8175795), (MGI:77358|PMID:7499277)

PMID:7499277 PMID:8175795

MGI:65996 MGI:77358

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Samsn1

SAM domain, SH3 domain and nuclear localization signals, 1

involved_in

(MGI:4437539|PMID:19923443)
PMID:21873635

PMID:19923443 PMID:21873635

MGI:4437539, RGD:13792537

NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900

Sema4d

semaphorin 4D

involved_in

(MGI:5297297|PMID:22019888)

PMID:22019888

MGI:5297297

NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138

Sfrp1

secreted frizzled-related protein 1

involved_in

(PMID:10980594)
GO_REF:0000107

PMID:10980594

GO_REF:0000107

NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286

Sfrp2

secreted frizzled-related protein 2

involved_in

(MGI:4835154|PMID:10980594)

PMID:10980594

MGI:4835154

NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063

Spink1

serine peptidase inhibitor, Kazal type 1

acts_upstream_of_or_within

(MGI:5428115|PMID:22228629)

PMID:22228629

MGI:5428115

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

negative regulation of phosphoprotein phosphatase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Bod1

biorientation of chromosomes in cell division 1

involved_in

(PMID:24157919)

PMID:24157919

NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787

Cmya5

cardiomyopathy associated 5

acts_upstream_of_or_within

(MGI:5056263|PMID:21427212)

PMID:21427212

MGI:5056263

NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364

Cry2

cryptochrome circadian regulator 2

involved_in

(PMID:9383998)
GO_REF:0000107

PMID:9383998

GO_REF:0000107

NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965

Fkbp1a

FKBP prolyl isomerase 1A

involved_in

(PMID:7592869)

PMID:7592869

NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743

Fkbp1b

FKBP prolyl isomerase 1B

involved_in

(PMID:7592869)

PMID:7592869

NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653

Mastl

microtubule associated serine/threonine kinase-like

involved_in

(PMID:20538976)

PMID:20538976

NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353

peptidylprolyl isomerase A

RGD

PMID:19832699

RGD:7247324

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

involved_in

PMID:21873635

GO_Central

NCBI chr20:1,601,350...1,604,857
Ensembl chr20:1,601,346...1,604,846

protein phosphatase 1, regulatory subunit 15A

involved_in

(PMID:11564868)

PMID:11564868

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

Ppp1r1b

protein phosphatase 1, regulatory (inhibitor) subunit 1B

involved_in

(PMID:10807923)

PMID:12016225 PMID:10585469

PMID:10807923

NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775

Ppp1r9b

protein phosphatase 1, regulatory subunit 9B

IDA
IMP

RGD

RGD:625568, RGD:9999389

NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083

Ppp4r4

protein phosphatase 4, regulatory subunit 4

involved_in
acts_upstream_of_or_within

PMID:21873635
(PMID:18715871)

PMID:18715871 PMID:21873635

NCBI chr 6:122,663,172...122,753,988
Ensembl chr 6:122,663,344...122,753,384

Ptpa

protein phosphatase 2 phosphatase activator

involved_in

(PMID:16916641)

PMID:16916641

NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549

regucalcin

RGD

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

Styxl1

serine/threonine/tyrosine interacting-like 1

involved_in

(PMID:24709986)

PMID:24709986

NCBI chr12:20,907,410...20,940,232
Ensembl chr12:20,907,435...20,939,752

Tiprl

TOR signaling pathway regulator

involved_in

(PMID:17384681)
GO_REF:0000107

PMID:17384681

GO_REF:0000107

NCBI chr13:77,527,176...77,552,026
Ensembl chr13:77,527,176...77,552,074

negative regulation of post-translational protein modification

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Crtap

cartilage associated protein

involved_in

(PMID:19846465)

PMID:19846465

NCBI chr 8:114,047,929...114,067,648
Ensembl chr 8:114,047,933...114,067,631

Flcn

folliculin

involved_in

(MGI:5487525|PMID:21209915)

PMID:21209915

MGI:5487525

NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769

P3h1

prolyl 3-hydroxylase 1

involved_in

(PMID:17277775), (PMID:22615817)
GO_REF:0000107

PMID:17277775 PMID:22615817

GO_REF:0000107

NCBI chr 5:132,841,868...132,856,664
Ensembl chr 5:132,841,928...132,856,659

Ube2b

ubiquitin-conjugating enzyme E2B

acts_upstream_of_or_within

MGI:2183933 (MGI:3720437|PMID:17488778)

PMID:17488778

MGI:3720437

NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665

negative regulation of protein acetylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Gsk3b

glycogen synthase kinase 3 beta

involved_in

PMID:18268107

ARUK-UCL

PMID:18268107

RGD:13514084

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

Hdac6

histone deacetylase 6

RGD

PMID:24464872

RGD:9681552

NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441

Parkinsonism associated deglycase

involved_in

GO_REF:0000024
(PMID:22683601)

ParkinsonsUK-UCL
RGD

PMID:22683601

GO_REF:0000024

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

sirtuin 1

involved_in

IMP
ISO

Rela
(PMID:23313858)
(PMID:17916362), (PMID:20203304)

PMID:17916362 PMID:20203304 PMID:23313858 PMID:22044919

RGD:10047123

NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260

negative regulation of protein autophosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adipoq

adiponectin, C1Q and collagen domain containing

involved_in

GO_REF:0000024
(PMID:12070119)

PMID:12070119

GO_REF:0000024

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

Chp1

calcineurin-like EF-hand protein 1

involved_in

PMID:12966074

UniProt

PMID:12966074

RGD:8553340

NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251

Eng

endoglin

involved_in

(PMID:12015308)

PMID:12015308

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

Enpp1

ectonucleotide pyrophosphatase/phosphodiesterase 1

involved_in

(PMID:11289049)

PMID:11289049

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

Errfi1

ERBB receptor feedback inhibitor 1

involved_in

(PMID:18046415)
GO_REF:0000107
GO_REF:0000024

PMID:18046415

GO_REF:0000024 GO_REF:0000107

NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282

Gfra2

GDNF family receptor alpha 2

RGD

PMID:9608533

RGD:632689

NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714

Impact

impact RWD domain protein

involved_in

GO_REF:0000024
(MGI:5494763|PMID:23447528)

PMID:23447528

GO_REF:0000024 MGI:5494763

NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569

Jun

Jun proto-oncogene, AP-1 transcription factor subunit

acts_upstream_of_or_within

(MGI:3662941|PMID:16916642)

PMID:16916642

MGI:3662941

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

Mvp

major vault protein

involved_in

(PMID:16441665)
GO_REF:0000107

PMID:16441665

GO_REF:0000107

NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380

Nlrp12

NLR family, pyrin domain containing 12

involved_in

(PMID:16203735)

PMID:16203735

NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934

Ptprc

protein tyrosine phosphatase, receptor type, C

acts_upstream_of_or_within

(MGI:65996|PMID:8175795), (MGI:77358|PMID:7499277)

PMID:7499277 PMID:8175795

MGI:65996 MGI:77358

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Tesk1

testis associated actin remodelling kinase 1

involved_in

PMID:18216281

ARUK-UCL

PMID:18216281

RGD:13461749

NCBI chr 5:57,691,922...57,697,698
Ensembl chr 5:57,691,969...57,697,698

negative regulation of protein autoubiquitination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Marchf7

membrane associated ring-CH-type finger 7

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:29295817)

PMID:29295817

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168

Taf1

TATA-box binding protein associated factor 1

involved_in

(PMID:17237821)

PMID:17237821

NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543

negative regulation of protein dephosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Akap1

A-kinase anchoring protein 1

NFATc3

RGD

PMID:19358331

RGD:2312604

NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896

Arpp19

cAMP-regulated phosphoprotein 19

involved_in

PMID:21873635

GO_Central

NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452

Ensa

endosulfine alpha

involved_in

PMID:21873635

GO_Central

NCBI chr 2:183,185,552...183,192,888
Ensembl chr 2:183,185,552...183,194,847

Igbp1

immunoglobulin binding protein 1

involved_in

(MGI:4457251|PMID:17438131), (MGI:4457259|PMID:9792806)

PMID:9792806 PMID:17438131

MGI:4457251 MGI:4457259

NCBI chr X:65,582,832...65,605,078
Ensembl chr X:65,582,821...65,606,049

LOC100360828

cAMP-regulated phosphoprotein 19-like

involved_in

PMID:21873635

GO_Central

NCBI chr 8:110,813,563...110,813,983
Ensembl chr 8:110,813,545...110,814,012

Mfhas1

multifunctional ROCO family signaling regulator 1

involved_in

(PMID:28609714)

PMID:28609714

NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743

protein phosphatase 1, regulatory subunit 15A

involved_in

(PMID:11564868)

PMID:11564868

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

Ppp1r16b

protein phosphatase 1, regulatory subunit 16B

involved_in

(PMID:21466834)

PMID:21466834

NCBI chr 3:147,323,652...147,419,658
Ensembl chr 3:147,324,126...147,418,937

Ppp1r8

protein phosphatase 1, regulatory subunit 8

involved_in

PMID:21873635

GO_Central

NCBI chr 5:145,031,632...145,048,753
Ensembl chr 5:145,031,498...145,048,752

Ptpa

protein phosphatase 2 phosphatase activator

involved_in

(PMID:16916641)

PMID:16916641

NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549

Ywhab

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

involved_in

(PMID:17255105)
GO_REF:0000107

PMID:17255105

GO_REF:0000107

NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105

Ywhae

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

acts_upstream_of_or_within
involved_in

(MGI:2665158|PMID:12796778)
GO_REF:0000107

PMID:12796778

GO_REF:0000107 MGI:2665158

NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589

negative regulation of protein deubiquitination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dnajb2

DnaJ heat shock protein family (Hsp40) member B2

involved_in

(PMID:15936278)

PMID:15936278

NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277

Trim21

tripartite motif-containing 21

involved_in

(PMID:16472766)

PMID:16472766

NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440

negative regulation of protein glutathionylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fxyd1

FXYD domain-containing ion transport regulator 1

involved_in

(PMID:21454534)
GO_REF:0000024

PMID:21454534

GO_REF:0000024

NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278

G6pd

glucose-6-phosphate dehydrogenase

involved_in

(PMID:17516514)

PMID:17516514

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

negative regulation of protein glycosylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Mgat4d

MGAT4 family, member D

involved_in

(MGI:5887193|PMID:20805325)

PMID:20805325

MGI:5887193

NCBI chr19:24,740,068...24,777,012
Ensembl chr19:24,740,078...24,777,012

O-GlcNAcase

RGD

NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359

negative regulation of protein K48-linked deubiquitination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Parkinsonism associated deglycase

involved_in

(PMID:21097510)
GO_REF:0000024

RGD
ParkinsonsUK-UCL

PMID:21097510

GO_REF:0000024

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

Ubxn1

UBX domain protein 1

involved_in

(PMID:21135095)
PMID:21873635

PMID:21135095 PMID:21873635

NCBI chr 1:205,765,212...205,769,236
Ensembl chr 1:205,745,120...205,816,520

negative regulation of protein K48-linked ubiquitination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

peptidylprolyl isomerase A

involved_in

(PMID:30328013)
GO_REF:0000024

PMID:30328013

GO_REF:0000024

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

peptidylprolyl isomerase A (cyclophilin A)-like 4D

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310

Trim44

tripartite motif-containing 44

involved_in

(PMID:23460740)
GO_REF:0000107

PMID:23460740

GO_REF:0000107

NCBI chr 3:88,597,962...88,729,085
Ensembl chr 3:88,592,719...88,729,188

negative regulation of protein K63-linked ubiquitination

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cep63

centrosomal protein 63

involved_in

ISS
ISO
IEA

GO_REF:0000024
(PMID:35989368)
GO_REF:0000107

UniProt
RGD
Ensembl

PMID:35989368

GO_REF:0000024 GO_REF:0000107

NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177

Gps2

G protein pathway suppressor 2

involved_in

(MGI:5896692|PMID:28039360), (MGI:6148392|PMID:24953653), (MGI:6148396|PMID:29499132), (MGI:6148454|PMID:22424771)

PMID:22424771 PMID:24953653 PMID:28039360 PMID:29499132

MGI:5896692 MGI:6148392 MGI:6148396 MGI:6148454

NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650

Mir138-1

microRNA 138-1

involved_in

(PMID:23319823)

PMID:23319823

NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064

Mir138-2

microRNA 138-2

involved_in

(PMID:23319823)

PMID:23319823

NCBI chr19:10,674,193...10,674,274
Ensembl chr19:10,674,193...10,674,274

Parp10

poly (ADP-ribose) polymerase family, member 10

involved_in

(PMID:23575687)

PMID:23575687

NCBI chr 7:107,949,031...107,958,377
Ensembl chr 7:107,949,043...107,958,304

Plaa

phospholipase A2, activating protein

involved_in

GO_REF:0000024
(MGI:5883825|PMID:28413018)

PMID:28413018

GO_REF:0000024 MGI:5883825

NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282

negative regulation of protein kinase activity

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adora2a

adenosine A2a receptor

in PC12 cells, PKCzeta deactivated after long-term activation of Adora2a

RGD

PMID:12590138

RGD:1625697

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

Akt1

AKT serine/threonine kinase 1

involved_in

IDA
IEA
ISO

PMID:8524413
GO_REF:0000107
(PMID:9373175)

PMID:9373175 PMID:8524413

GO_REF:0000107, RGD:8554844

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

Akt1s1

AKT1 substrate 1

involved_in

PMID:21873635
(PMID:17386266)

PMID:17386266 PMID:21873635

NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677

Camk2n1

calcium/calmodulin-dependent protein kinase II inhibitor 1

involved_in

PMID:21873635

GO_Central

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

Camk2n2

calcium/calmodulin-dependent protein kinase II inhibitor 2

involved_in

PMID:21873635

GO_Central

NCBI chr11:80,289,702...80,290,829

Cav3

caveolin 3

acts_upstream_of_or_within

(MGI:2682500|PMID:14600260)

PMID:14600260

MGI:2682500

NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137

Cdkn2a

cyclin-dependent kinase inhibitor 2A

involved_in

(PMID:15582998)

PMID:15582998

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Ceacam1

CEA cell adhesion molecule 1

involved_in

GO_REF:0000024
(MGI:5478702|PMID:22496641)

PMID:22496641

GO_REF:0000024 MGI:5478702

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

Cep43

centrosomal protein 43

involved_in

(PMID:17888034)

PMID:17888034

NCBI chr 1:52,533,418...52,564,025
Ensembl chr 1:52,533,428...52,563,923

Cep85

centrosomal protein 85

involved_in

(PMID:26220856)

PMID:26220856

NCBI chr 5:146,356,575...146,404,155
Ensembl chr 5:146,356,576...146,404,060

Chp1

calcineurin-like EF-hand protein 1

involved_in

PMID:12966074

UniProt

PMID:12966074

RGD:8553340

NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251

Daxx

death-domain associated protein

RGD

PMID:17289031

RGD:9587773

NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843

Dbndd1

dysbindin domain containing 1

involved_in

PMID:21873635

GO_Central

NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444

Dbndd2

dysbindin domain containing 2

involved_in

(PMID:16618118)
PMID:21873635

PMID:16618118 PMID:21873635

NCBI chr 3:153,193,213...153,220,651
Ensembl chr 3:153,191,090...153,220,651

Deptor

DEP domain containing MTOR-interacting protein

involved_in

(PMID:19446321)
PMID:21873635

PMID:19446321 PMID:21873635

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

Dnaja3

DnaJ heat shock protein family (Hsp40) member A3

involved_in

(PMID:15601829)

PMID:15601829

NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161

dopamine receptor D1

RGD

NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002

dopamine receptor D5

RGD

NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774

Dtnbp1

dystrobrevin binding protein 1

involved_in

PMID:21873635

GO_Central

NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661

Dusp19

dual specificity phosphatase 19

involved_in

(MGI:2182169|PMID:11959862)

PMID:11959862

MGI:2182169

NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534

Dvl1

dishevelled segment polarity protein 1

involved_in

(PMID:10330181)

PMID:10330181

NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664

ENSRNOG00000068283

involved_in

GO_REF:0000002

InterPro

GO_REF:0000002

Ensembl chr 6:44,214,352...44,214,555

Epha1

Eph receptor A1

involved_in

(PMID:19118217)

PMID:19118217

NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846

Ephb2

Eph receptor B2

acts_upstream_of

(MGI:5905277|PMID:11585923)

PMID:11585923

MGI:5905277

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

Fabp4

fatty acid binding protein 4

acts_upstream_of_or_within

MGI:2148887 (MGI:3578695|PMID:15684432)

PMID:15684432

MGI:3578695

NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578

Gadd45a

growth arrest and DNA-damage-inducible, alpha

acts_upstream_of_or_within

(MGI:2384369|PMID:12124778)

PMID:12124778

MGI:2384369

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

Gadd45b

growth arrest and DNA-damage-inducible, beta

acts_upstream_of_or_within

(MGI:2384369|PMID:12124778)

PMID:12124778

MGI:2384369

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

Gadd45g

growth arrest and DNA-damage-inducible, gamma

acts_upstream_of_or_within

(MGI:2384369|PMID:12124778)

PMID:12124778

MGI:2384369

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

Gnaq

G protein subunit alpha q

involved_in

(PMID:20399743)

PMID:20399743

NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672

Gskip

GSK3B interacting protein

involved_in

(PMID:16981698)
GO_REF:0000107
GO_REF:0000024

PMID:16981698

GO_REF:0000024 GO_REF:0000107

NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100

Gstp1

glutathione S-transferase pi 1

involved_in

IMP
ISO

(PMID:16636664)

PMID:16636664 PMID:21668448

RGD:10401931

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

Hspb1

heat shock protein family B (small) member 1

involved_in

(MGI:3581090|PMID:15731106)
GO_REF:0000107

PMID:15731106

GO_REF:0000107 MGI:3581090

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

Il6

interleukin 6

Phospholamban phosphorylation

RGD

PMID:15845578

RGD:2306941

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Ilk

integrin-linked kinase

GSK-3 activity as a Tau protein kinase

RGD

PMID:12629168

RGD:2302091

NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140

inositol polyphosphate-5-phosphatase K

involved_in

(PMID:12556481)

PMID:12556481

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

Itgb1bp1

integrin subunit beta 1 binding protein 1

involved_in

(PMID:20616313)

PMID:20616313

NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037

Lrp6

LDL receptor related protein 6

involved_in

(PMID:16365045)

PMID:16365045

NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497

Mir20a

microRNA 20a

involved_in

(PMID:25447536)

PMID:25447536

NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168

Mllt1

MLLT1, super elongation complex subunit

acts_upstream_of_or_within

(MGI:1891804|PMID:11007757)

PMID:11007757

MGI:1891804

NCBI chr 9:1,731,077...1,775,985
Ensembl chr 9:1,731,080...1,775,970

Nf1

neurofibromin 1

involved_in
acts_upstream_of_or_within

PMID:16835260 PMID:17053831

GO_REF:0000024
MGI:1339753|MGI:1857478 (MGI:3655425|PMID:16835260), (MGI:3689489|PMID:17053831)

HGNC-UCL
RGD

GO_REF:0000024 MGI:3655425 MGI:3689489

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

Nf2

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

acts_upstream_of_or_within
involved_in

(MGI:2679135|PMID:14580336), (MGI:3613261|PMID:16405865)
GO_REF:0000107

PMID:14580336 PMID:16405865

GO_REF:0000107 MGI:2679135 MGI:3613261

NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667

Parkinsonism associated deglycase

involved_in

UniProtKB:Q99683|UniProtKB:Q9UER7 (PMID:15983381)
GO_REF:0000024

RGD
ParkinsonsUK-UCL

PMID:15983381

GO_REF:0000024

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

Pcp4

Purkinje cell protein 4

RGD

PMID:10751438

RGD:1579763

NCBI chr11:35,759,711...35,861,725
Ensembl chr11:35,800,713...35,861,725

Pdpk1

3-phosphoinositide dependent protein kinase-1

involved_in

(PMID:9373175)
GO_REF:0000107

PMID:9218452 PMID:1491692

PMID:9373175

GO_REF:0000107

NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623

Pkia

cAMP-dependent protein kinase inhibitor alpha

involved_in
acts_upstream_of_or_within

TAS
IEA
ISO

GO_REF:0000002
(MGI:894256|PMID:9218452)

InterPro
RGD

GO_REF:0000002 MGI:894256, RGD:729428

NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282

Pkib

cAMP-dependent protein kinase inhibitor beta

involved_in

GO_REF:0000002

InterPro

GO_REF:0000002

NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187

Pkig

cAMP-dependent protein kinase inhibitor gamma

acts_upstream_of_or_within

(MGI:894256|PMID:9218452)

PMID:9218452

MGI:894256

NCBI chr 3:152,330,486...152,398,085
Ensembl chr 3:152,366,041...152,398,082

Pkn1

protein kinase N1

acts_upstream_of_or_within
involved_in

MGI:5475202 (MGI:5467878|PMID:23223530)
GO_REF:0000107

PMID:23223530

GO_REF:0000107 MGI:5467878

NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107

Plec

plectin

involved_in

(MGI:2386377|PMID:12200133)
GO_REF:0000107

PMID:12200133

GO_REF:0000107 MGI:2386377

NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467

peptidylprolyl isomerase A

involved_in

(PMID:26095851)
GO_REF:0000024

PMID:26095851

GO_REF:0000024

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

peptidylprolyl isomerase A (cyclophilin A)-like 4D

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310

Ppm1e

protein phosphatase, Mg2+/Mn2+ dependent, 1E

involved_in

(PMID:11864573)
PMID:21873635

PMID:11864573 PMID:21873635

NCBI chr10:72,051,643...72,187,439
Ensembl chr10:72,055,208...72,187,282

Ppm1f

protein phosphatase, Mg2+/Mn2+ dependent, 1F

involved_in

ISS
IBA
ISO

GO_REF:0000024
PMID:21873635
(PMID:11864573)

PMID:11864573 PMID:21873635

GO_REF:0000024, RGD:13792537

NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340

Prkag2

protein kinase AMP-activated non-catalytic subunit gamma 2

involved_in

(PMID:17255938)

PMID:17255938

NCBI chr 4:10,010,574...10,252,152
Ensembl chr 4:10,010,890...10,252,142

Prkar1a

protein kinase cAMP-dependent type I regulatory subunit alpha

acts_upstream_of_or_within

MGI:2182091|MGI:3512112 (MGI:3821563|PMID:18316483)

PMID:18316483

MGI:3821563

NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041

Prkca

protein kinase C, alpha

acts_upstream_of_or_within

MGI:2679305 (MGI:2677557|PMID:11923480)

PMID:11923480

MGI:2677557

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

Prkrip1

PRKR interacting protein 1

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:2665232|PMID:12679338)

PMID:12679338 PMID:21873635

MGI:2665232, RGD:13792537

NCBI chr12:20,470,802...20,491,789
Ensembl chr12:20,470,820...20,489,115

Psen1

presenilin 1

acts_upstream_of_or_within

(MGI:2664026|PMID:12805290)

PMID:12805290

MGI:2664026

NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650

Ptprc

protein tyrosine phosphatase, receptor type, C

involved_in

ISS
ISO
IBA

GO_REF:0000024
(MGI:1889764|PMID:10970857)
PMID:21873635
(PMID:9197241)

PMID:9197241 PMID:10970857 PMID:21873635

GO_REF:0000024 MGI:1889764, RGD:13792537

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

Qars1

glutaminyl-tRNA synthetase 1

involved_in

(PMID:11096076)
GO_REF:0000107

PMID:11096076

GO_REF:0000107

NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739

Rb1

RB transcriptional corepressor 1

involved_in

GO_REF:0000024
GO_REF:0000107
UniProtKB:P21675 (PMID:9858607)

PMID:9858607

GO_REF:0000024 GO_REF:0000107

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

regucalcin

RGD

NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450

Rtraf

RNA transcription, translation and transport factor

involved_in

(PMID:15147888)

PMID:15147888

NCBI chr15:4,447,243...4,457,973
Ensembl chr15:4,442,573...4,457,972

Sh3bp5

SH3-domain binding protein 5

involved_in

(MGI:1337389|PMID:10339589)

PMID:10339589

MGI:1337389

NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975

Shb

SH2 domain containing adaptor protein B

acts_upstream_of_or_within

MGI:3721903 (MGI:5527493|PMID:23528453)

PMID:23528453

MGI:5527493

NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538

Smcr8

SMCR8-C9orf72 complex subunit

involved_in

(PMID:28195531)

PMID:28195531

NCBI chr10:45,457,962...45,465,101
Ensembl chr10:45,457,605...45,468,876

Smyd3

SET and MYND domain containing 3

acts_upstream_of_or_within

(MGI:5500979|PMID:23752591)

PMID:23752591

MGI:5500979

NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253

Spred1

sprouty-related, EVH1 domain containing 1

involved_in

(PMID:18216281)

PMID:18216281

NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718

Sys1

Sys1 golgi trafficking protein

involved_in

PMID:21873635

GO_Central

NCBI chr 3:153,190,970...153,195,463
Ensembl chr 3:153,191,090...153,220,651

Taf7

TATA-box binding protein associated factor 7

involved_in

(PMID:18391197)

PMID:15093746 PMID:21873635

PMID:18391197

NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134

Thy1

Thy-1 cell surface antigen

involved_in

IDA
IBA

PMID:15093746
PMID:21873635

UniProt
GO_Central

RGD:8553684, RGD:13792537

NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659

Trib1

tribbles pseudokinase 1

involved_in

(PMID:15299019)

PMID:15299019

NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731

Trib3

tribbles pseudokinase 3

involved_in

GO_REF:0000024
(MGI:3687885|PMID:12791994)
(PMID:12791994)

PMID:12791994

GO_REF:0000024 MGI:3687885

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

Trim27

tripartite motif-containing 27

involved_in

(PMID:22128329)

PMID:22128329

NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643

Tsc2

TSC complex subunit 2

acts_upstream_of_or_within

(MGI:3050929|PMID:15249583)

PMID:15249583

MGI:3050929

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

Ubash3b

ubiquitin associated and SH3 domain containing, B

involved_in
acts_upstream_of_or_within

PMID:21873635
(MGI:4838721|PMID:20585042), (MGI:5811934|PMID:27609517)

PMID:20585042 PMID:27609517 PMID:21873635

MGI:4838721 MGI:5811934, RGD:13792537

NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201

Wars1

tryptophanyl-tRNA synthetase 1

involved_in

(PMID:22504299)

PMID:22504299

NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269

Wnk4

WNK lysine deficient protein kinase 4

involved_in

MGI:6414871 (MGI:6283264|PMID:30765526)

PMID:30765526

MGI:6283264

NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829

Wwtr1

WW domain containing transcription regulator 1

involved_in

(PMID:20412773)

PMID:20412773

NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968

negative regulation of protein kinase activity by regulation of protein phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adar

adenosine deaminase, RNA-specific

involved_in

(PMID:18362360), (PMID:19651874)
GO_REF:0000107
(MGI:5447606|PMID:18362360)
GO_REF:0000024

PMID:18362360 PMID:19651874

GO_REF:0000024 GO_REF:0000107 MGI:5447606

NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282

Adarb1

adenosine deaminase, RNA-specific, B1

involved_in

ISO
ISS
IEA

(PMID:21289159)
GO_REF:0000024
GO_REF:0000107

RGD
UniProt
Ensembl

PMID:21289159

GO_REF:0000024 GO_REF:0000107

NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852

CDK5 regulatory subunit associated protein 3

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:21283629)

PMID:21283629

GO_REF:0000024 GO_REF:0000107

NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590

Coro1c

coronin 1C

involved_in

(PMID:19913511)

PMID:19913511

NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179

Dusp10

dual specificity phosphatase 10

acts_upstream_of_or_within

(MGI:5532582|PMID:23977283)

PMID:23977283

MGI:5532582

NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716

Npm1

nucleophosmin 1

involved_in

(PMID:12882984)
GO_REF:0000024

PMID:12882984

GO_REF:0000024

NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645

Ppm1f

protein phosphatase, Mg2+/Mn2+ dependent, 1F

involved_in

GO_REF:0000024
(PMID:15140879)

PMID:15140879

GO_REF:0000024

NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340

negative regulation of protein lipidation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dbi

diazepam binding inhibitor

involved_in

(PMID:21079819)

PMID:21079819

NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693

negative regulation of protein modification process

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein phosphatase 1, regulatory subunit 15A

involved_in

GO_REF:0000117

GO_REF:0000117

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

negative regulation of protein neddylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cdkn2a

cyclin-dependent kinase inhibitor 2A

involved_in

(PMID:18560357)

PMID:18560357

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

Cops9

COP9 signalosome subunit 9

involved_in

(PMID:23776465)
PMID:21873635

PMID:23776465 PMID:21873635

NCBI chr 9:93,209,843...93,214,774
Ensembl chr 9:93,209,843...93,213,317

Dcun1d3

defective in cullin neddylation 1 domain containing 3

involved_in

(PMID:26906416)
GO_REF:0000024

PMID:26906416

GO_REF:0000024

NCBI chr 1:174,243,001...174,285,647
Ensembl chr 1:66,494,848...66,496,343
Ensembl chr 1:66,494,848...66,496,343

Rpl11

ribosomal protein L11

involved_in

(PMID:18560357)

PMID:18560357

NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599

Rpl5

ribosomal protein L5

involved_in

(PMID:18560357)

PMID:18560357

NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290

negative regulation of protein phosphorylation

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

involved_in

GO_REF:0000107

GO_REF:0000107

activity-dependent neuroprotector homeobox

involved_in

(MGI:6447854|PMID:32533114)

PMID:32533114

MGI:6447854

NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312

Ager

advanced glycosylation end product-specific receptor

Smad2

RGD

PMID:21743278

RGD:7243870

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

Angpt1

angiopoietin 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(MGI:4437182|PMID:20060382)

PMID:20060382

GO_REF:0000107 MGI:4437182

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

Arrb1

arrestin, beta 1

ERK

RGD

PMID:19254952

RGD:5509898

NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061

Arrb2

arrestin, beta 2

involved_in

(MGI:5784966|PMID:24974728)
GO_REF:0000107

PMID:24974728

GO_REF:0000107 MGI:5784966

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

Atg14

autophagy related 14

involved_in

GO_REF:0000024
(MGI:5619439|PMID:23332761)

PMID:23332761

GO_REF:0000024 MGI:5619439

NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113

Bag1

BAG cochaperone 1

acts_upstream_of_or_within

MGI:3528234 (MGI:3603966|PMID:16116448)

PMID:16116448

MGI:3603966

NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075

Bdkrb1

bradykinin receptor B1

inhibition increases phosphorylation of ERK, p38, JNK and Thr495 of eNOS in SHR-SP rats

RGD

PMID:16497153

RGD:1625749

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

Cactin

cactin, spliceosome C complex subunit

involved_in

(PMID:20829348)

PMID:20829348

NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829

Cadm1

cell adhesion molecule 1

RGD

PMID:23769722

RGD:152975632

NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833

Cadm4

cell adhesion molecule 4

involved_in

(PMID:25893857)
(MGI:6271409|PMID:25893857)

PMID:25893857

MGI:6271409

NCBI chr 1:80,075,232...80,096,511
Ensembl chr 1:80,075,202...80,097,423

Ccnb1

cyclin B1

MAPK

RGD

PMID:15291744

RGD:1578405

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

Cd109

CD109 molecule

acts_upstream_of_or_within

MGI:5443927 (MGI:5441431|PMID:22490868)

PMID:22490868

MGI:5441431

NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194

CDK5 regulatory subunit associated protein 3

involved_in

(PMID:17785205)
GO_REF:0000024

PMID:17785205

GO_REF:0000024

NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590

Cdkn1a

cyclin-dependent kinase inhibitor 1A

involved_in

(PMID:7958916)

PMID:7958916

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

Chp1

calcineurin-like EF-hand protein 1

involved_in

PMID:12966074

UniProt

PMID:12966074

RGD:8553340

NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251

Chrna7

cholinergic receptor nicotinic alpha 7 subunit

involved_in

GO_REF:0000107
(MGI:3843740|PMID:19230830)

PMID:19230830

GO_REF:0000107 MGI:3843740

NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240

Cib1

calcium and integrin binding 1

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5314162|PMID:22128142)

PMID:22128142

GO_REF:0000024 GO_REF:0000107 MGI:5314162

NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423

Coro1c

coronin 1C

involved_in

(PMID:19913511)

PMID:19913511

NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179

Crkl

CRK like proto-oncogene, adaptor protein

involved_in

(PMID:23959425)

PMID:23959425

NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238

Ctdsp1

CTD small phosphatase 1

acts_upstream_of_or_within

(MGI:5494382|PMID:22210897)

NCBI chr 9:75,973,694...75,979,298
Ensembl chr 9:75,973,962...75,979,297

Ctdsp2

CTD small phosphatase 2

acts_upstream_of_or_within

(MGI:5494382|PMID:22210897)

NCBI chr 7:62,805,400...62,825,306
Ensembl chr 7:62,805,658...62,825,302

Ctdspl

CTD small phosphatase like

acts_upstream_of_or_within

(MGI:5494382|PMID:22210897)

NCBI chr 8:118,642,729...118,767,238
Ensembl chr 8:118,642,672...118,767,117

Dab2ip

DAB2 interacting protein

involved_in

GO_REF:0000024
(MGI:3831615|PMID:19033661)
(PMID:20080667)

PMID:19033661 PMID:20080667

GO_REF:0000024 MGI:3831615

NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280

Dnajc10

DnaJ heat shock protein family (Hsp40) member C10

involved_in

(PMID:19122239)

PMID:19122239

NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719

dopamine receptor D2

RGD

NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875

Dusp6

dual specificity phosphatase 6

acts_upstream_of_or_within

MGI:3827011 (MGI:3822592|PMID:18753132)

PMID:18753132

MGI:3822592

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

Dvl1

dishevelled segment polarity protein 1

acts_upstream_of_or_within

UniProtKB:P49841 (MGI:1095215|PMID:9271238)

PMID:9271238

MGI:1095215

NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664

Ephb2

Eph receptor B2

involved_in

(MGI:5905277|PMID:11585923)

PMID:11585923

MGI:5905277

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

Fbln1

fibulin 1

involved_in

(PMID:11792823)

PMID:11792823

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

Fkbp8

FKBP prolyl isomerase 8

involved_in

(PMID:15733859)

PMID:15733859

NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612

Hspa4

heat shock protein family A (Hsp70) member 4

Nfkbia

RGD

PMID:17473852

RGD:5688754

NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001

Ibtk

inhibitor of Bruton tyrosine kinase

acts_upstream_of_or_within
involved_in

(PMID:11577348)
PMID:21873635

PMID:11577348 PMID:21873635

NCBI chr 8:86,625,591...86,698,661
Ensembl chr 8:86,625,597...86,698,260

Igfbp3

insulin-like growth factor binding protein 3

acts_upstream_of_or_within
involved_in

(PMID:17591901)
GO_REF:0000107

PMID:17591901

GO_REF:0000107

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

interleukin 2

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

Impact

impact RWD domain protein

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(MGI:5494763|PMID:23447528)
(MGI:3589702|PMID:15937339)

PMID:15937339 PMID:23447528

GO_REF:0000024 MGI:3589702 MGI:5494763

NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569

inositol polyphosphate-5-phosphatase K

involved_in

(MGI:5299272|PMID:21938401)

PMID:21938401

MGI:5299272

NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773

Insm1

INSM transcriptional repressor 1

involved_in

(PMID:19124461)

PMID:19124461

NCBI chr 3:133,639,790...133,642,963
Ensembl chr 3:133,639,580...133,643,003

Insr

insulin receptor

Stat3 in hypothalamus

RGD

PMID:17585961

RGD:2290473

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

Kirrel1

kirre like nephrin family adhesion molecule 1

acts_upstream_of_or_within

MGI:2442334 (MGI:4950838|PMID:21306299)

PMID:21306299

MGI:4950838

NCBI chr 2:172,521,644...172,615,057
Ensembl chr 2:172,525,245...172,615,299

Kirrel2

kirre like nephrin family adhesion molecule 2

acts_upstream_of_or_within

MGI:1891396 (MGI:4950838|PMID:21306299)

PMID:21306299

MGI:4950838

NCBI chr 1:85,708,793...85,718,670
Ensembl chr 1:85,708,793...85,718,670

Klhl31

kelch-like family member 31

involved_in

(PMID:18719355)

PMID:18719355

NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873

Lrp6

LDL receptor related protein 6

involved_in

(PMID:16365045)

PMID:16365045

NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497

Lrrk2

leucine-rich repeat kinase 2

involved_in

GO_REF:0000024
(MGI:5553024|PMID:24464040)

ParkinsonsUK-UCL
RGD

PMID:24464040

GO_REF:0000024 MGI:5553024

NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703

Lyn

LYN proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000024
(MGI:2687173|PMID:14525964)

PMID:14525964

GO_REF:0000024 MGI:2687173

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

Mas1

MAS1 proto-oncogene, G protein-coupled receptor

ERK1/ERK2

RGD

PMID:15951342

RGD:1581938

NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709

Men1

menin 1

involved_in

(PMID:12226747)

PMID:12226747

NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871

Mical1

microtubule associated monooxygenase, calponin and LIM domain containing 1

involved_in

(MGI:5142343|PMID:21730291)

PMID:21730291

MGI:5142343

NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089

Mir137

microRNA 137

involved_in

(PMID:30102687)

PMID:30102687

NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985

Mir26a

microRNA 26a

acts_upstream_of_or_within

(MGI:5494382|PMID:22210897)

NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378

Mir26b

microRNA 26b

acts_upstream_of_or_within

(MGI:5494382|PMID:22210897)

NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680

Mtor

mechanistic target of rapamycin kinase

RGD

PMID:21357504

RGD:10041003

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

Myadm

myeloid-associated differentiation marker

involved_in

(PMID:23264465)
GO_REF:0000107

PMID:23264465

GO_REF:0000107

NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035

Niban1

niban apoptosis regulator 1

involved_in

GO_REF:0000024
(MGI:3716265|PMID:17588536)

PMID:17588536

GO_REF:0000024 MGI:3716265

NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729

Nnt

nicotinamide nucleotide transhydrogenase

RGD

PMID:22198343

RGD:13513982

NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823

Ntrk3

neurotrophic receptor tyrosine kinase 3

involved_in

(PMID:23027130)
GO_REF:0000107

GO_REF:0000107

NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286

Ocln

occludin

involved_in

(PMID:28718701)

PMID:28718701

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase

Mapk1, Mapk3

RGD

PMID:21712532

RGD:9590189

NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146

Paqr3

progestin and adipoQ receptor family member 3

acts_upstream_of_or_within

MGI:3757569 (MGI:3722998|PMID:17724343)
(PMID:17724343)

PMID:17724343

MGI:3722998

NCBI chr14:12,462,568...12,484,999
Ensembl chr14:12,462,563...12,479,994

Pard6a

par-6 family cell polarity regulator alpha

acts_upstream_of_or_within
involved_in

MGI:97595 (MGI:5529726|PMID:24305805)
GO_REF:0000107

PMID:24305805

GO_REF:0000107 MGI:5529726

NCBI chr19:33,589,583...33,591,900
Ensembl chr19:33,589,542...33,591,900

Parkinsonism associated deglycase

involved_in

UniProtKB:Q99683|UniProtKB:Q9UER7 (PMID:15983381)
GO_REF:0000024

RGD
ParkinsonsUK-UCL

PMID:15983381

GO_REF:0000024

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

Pax6

paired box 6

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1856155 (MGI:3622497|PMID:16497297)

PMID:16497297

GO_REF:0000107 MGI:3622497

NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014

Pbk

PDZ binding kinase

acts_upstream_of_or_within

MGI:5293435 (MGI:5293269|PMID:21715333)

PMID:21715333

MGI:5293269

NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014

Pebp1

phosphatidylethanolamine binding protein 1

RGD

PMID:15886202

RGD:1580668

NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862

Pid1

phosphotyrosine interaction domain containing 1

involved_in

(PMID:19079291)

PMID:19079291

NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044

Pip5kl1

phosphatidylinositol-4-phosphate 5-kinase-like 1

involved_in

(PMID:19680787)

PMID:19680787

NCBI chr 3:15,860,493...15,869,264
Ensembl chr 3:15,855,946...15,869,165

Pkn1

protein kinase N1

acts_upstream_of_or_within

MGI:5475202 (MGI:5467878|PMID:23223530)

PMID:23223530

MGI:5467878

NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107

Plpp3

phospholipid phosphatase 3

involved_in

(PMID:20123964)
GO_REF:0000107
(MGI:4820698|PMID:20123964)

PMID:20123964

GO_REF:0000107 MGI:4820698

NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205

Ppargc1a

PPARG coactivator 1 alpha

Mapk1, Mapk3

RGD

PMID:19786068

RGD:10059654

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

peptidylprolyl isomerase A

involved_in

GO_REF:0000024
(PMID:26095851)

PMID:26095851

GO_REF:0000024

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

peptidylprolyl isomerase A (cyclophilin A)-like 4D

involved_in

GO_REF:0000024

GO_REF:0000024

NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310

Ppp1r15b

protein phosphatase 1, regulatory subunit 15B

involved_in

(PMID:26307080)

PMID:26307080

NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737

Ppp2ca

protein phosphatase 2 catalytic subunit alpha

PMID:18832448 PMID:26732138

AMPK alpha

RGD

RGD:8693393, RGD:11572421

NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862

Ppp5c

protein phosphatase 5, catalytic subunit

Mapk1, Mapk3, Mapk8, Mapk9

RGD

PMID:19686245

RGD:8693743

NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456

Prkca

protein kinase C, alpha

acts_upstream_of_or_within

MGI:1927223|MGI:3037088 (MGI:3033566|PMID:14966518), (MGI:5529726|PMID:24305805)

PMID:14966518 PMID:24305805

MGI:3033566 MGI:5529726

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

Prkdc

protein kinase, DNA-activated, catalytic subunit

involved_in

(MGI:5554971|PMID:24158435)

ParkinsonsUK-UCL
Ensembl
RGD

PMID:24158435

MGI:5554971

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

Prkn

parkin RBR E3 ubiquitin protein ligase

involved_in

ISS
IEA
IBA
ISO

GO_REF:0000024
GO_REF:0000107
PMID:21873635
(PMID:17512523)

PMID:17512523 PMID:21873635

GO_REF:0000024 GO_REF:0000107, RGD:13792537

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

Prnp

prion protein

involved_in

(MGI:4943618|PMID:20145049)

PMID:20145049

MGI:4943618

NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937

Prr5l

proline rich 5 like

involved_in

(PMID:22609986)
GO_REF:0000107
GO_REF:0000024

PMID:22609986

GO_REF:0000024 GO_REF:0000107

NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763

Psen1

presenilin 1

acts_upstream_of_or_within

MGI:109284 (MGI:3044464|PMID:15148382)