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ONTOLOGY REPORT - ANNOTATIONS

Term:reactive oxygen species metabolic process
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Accession:GO:0072593 term browser browse the term
Definition:The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Synonyms:exact_synonym: ROS metabolic process;   reactive oxygen species metabolism


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reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within ISO (PMID:19096392) RGD PMID:19096392 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857134 (PMID:10726970), (PMID:12855558), (PMID:9681465)		 Ensembl
RGD		 PMID:9681465 PMID:10726970 PMID:12855558 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO
ISS		 (PMID:10891486)
GO_REF:0000024		 RGD
UniProt		 PMID:10891486 GO_REF:0000024 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:19364818) RGD PMID:19364818 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 acts_upstream_of_or_within ISO (PMID:19364818) RGD PMID:19364818 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO MGI:2153356 (PMID:20716577) RGD PMID:20716577 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Cyb5r4 cytochrome b5 reductase 4 involved_in ISO (PMID:15131110) RGD PMID:15131110 NCBI chr 8:87,975,596...88,048,356
Ensembl chr 8:87,981,116...88,045,832 		JBrowse link
G Cyba cytochrome b-245 alpha chain acts_upstream_of_or_within ISO MGI:3526726 (PMID:24185898) RGD PMID:24185898 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:20176937)		 Ensembl
RGD		 PMID:20176937 GO_REF:0000107 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Drd5 dopamine receptor D5 involved_in ISO
IEA		 (PMID:16352863)
GO_REF:0000107		 RGD
Ensembl		 PMID:16352863 GO_REF:0000107 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Duox1 dual oxidase 1 acts_upstream_of_or_within ISO MGI:2384861 (PMID:20233719) RGD PMID:20233719 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Gls2 glutaminase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20351271)
GO_REF:0000107		 RGD
Ensembl		 PMID:20351271 GO_REF:0000107 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:12370360) RGD PMID:12370360 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il22 interleukin 22 acts_upstream_of_or_within ISO (PMID:12700595) RGD PMID:12700595 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:3041135 (PMID:23994610) RGD PMID:23994610 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mpv17 mitochondrial inner membrane protein MPV17 acts_upstream_of_or_within ISO (PMID:7957077) RGD PMID:7957077 NCBI chr 6:25,221,668...25,236,241
Ensembl chr 6:25,222,896...25,236,244 		JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:16631601) RGD PMID:16631601 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649 		JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 acts_upstream_of_or_within ISO (PMID:17189252) RGD PMID:17189252 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO (PMID:16826196) RGD PMID:16826196 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 involved_in ISO
ISS		 (PMID:15186778), (PMID:16478720), (PMID:16870178)
GO_REF:0000024		 RGD
UniProt		 PMID:15186778 PMID:16478720 PMID:16870178 GO_REF:0000024 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in ISO (PMID:16826196) RGD PMID:16826196 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16870178)
MGI:3793713 (PMID:29501746)
GO_REF:0000107		 RGD
Ensembl		 PMID:16870178 PMID:29501746 GO_REF:0000107 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 acts_upstream_of_or_within ISO (PMID:33323934) RGD PMID:33323934 NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase involved_in ISO (PMID:22634753) RGD PMID:22634753 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISO (MGI:5009390|PMID:17942966) RGD PMID:17942966 MGI:5009390 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:17448897) RGD PMID:17448897 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pax2 paired box 2 involved_in ISO (MGI:5009394|PMID:17538188) RGD PMID:17538188 MGI:5009394 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:17942966)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17942966 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21852536)		 UniProt
Ensembl
RGD		 PMID:21852536 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19197340)		 UniProt
RGD		 PMID:19197340 GO_REF:0000024 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14699081) RGD PMID:14699081 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Prdx4 peroxiredoxin 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11229364)
GO_REF:0000107		 RGD
Ensembl		 PMID:11229364 GO_REF:0000107 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 acts_upstream_of_or_within ISO MGI:98923 (PMID:21179475) RGD PMID:21179475 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688 		JBrowse link
G Rfk riboflavin kinase acts_upstream_of_or_within ISO MGI:104798|MGI:2156367 (PMID:19641494) RGD PMID:19641494 NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438
Ensembl chr  X:214,799,825...214,807,438 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of ISO (PMID:19498109) RGD PMID:19498109 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Sesn1 sestrin 1 involved_in ISO (PMID:15105503) RGD PMID:15105503 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:15105503), (PMID:26612684) RGD PMID:15105503 PMID:26612684 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sh3pxd2a SH3 and PX domains 2A involved_in ISO (MGI:5285168|PMID:19755709) RGD PMID:19755709 MGI:5285168 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166 		JBrowse link
G Snord33 small nucleolar RNA, C/D box 33 acts_upstream_of_or_within ISO MGI:1351319|MGI:1351324|MGI:1351325 (PMID:27820699) RGD PMID:27820699 NCBI chr 1:95,610,699...95,610,783
Ensembl chr 1:95,610,699...95,610,783 		JBrowse link
G Snord34 small nucleolar RNA, C/D box 34 acts_upstream_of_or_within ISO MGI:1351319|MGI:1351323|MGI:1351324 (PMID:27820699) RGD PMID:27820699 NCBI chr 8:115,045,817...115,045,883
Ensembl chr 8:115,045,817...115,045,883 		JBrowse link
G Snord35a small nucleolar RNA, C/D box 35A acts_upstream_of_or_within ISO MGI:1351323|MGI:1351324|MGI:1351325 (PMID:27820699) RGD PMID:27820699 NCBI chr 1:95,610,185...95,610,264
Ensembl chr 1:95,610,185...95,610,264 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
ISS		 (PMID:24140062)
GO_REF:0000024		 RGD
UniProt		 PMID:24140062 GO_REF:0000024 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of ISO MGI:5319187 (PMID:22044588) RGD PMID:22044588 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1857263 (PMID:22044588)		 Ensembl
RGD		 PMID:22044588 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ucp2 uncoupling protein 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5766079|PMID:26919426)		 UniProt
RGD		 PMID:26919426 GO_REF:0000024 MGI:5766079 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3040696 (PMID:21178006)		 Ensembl
RGD		 PMID:21178006 GO_REF:0000107 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
cellular detoxification of hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase involved_in ISO (PMID:18379038) RGD PMID:18379038 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Txn1 thioredoxin 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q99497 (PMID:22492997)		 Ensembl
RGD		 PMID:22492997 GO_REF:0000107 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
detoxification of hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA
ISS		 (PMID:14749723)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:14749723 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:32169171)		 Ensembl
UniProt
RGD		 PMID:32169171 GO_REF:0000024 GO_REF:0000107 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Cyba cytochrome b-245 alpha chain involved_in IMP PMID:8798532 BHF-UCL PMID:8798532 RGD:2317869 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain acts_upstream_of_or_within ISO MGI:1857284 (PMID:15258578) RGD PMID:15258578 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 acts_upstream_of_or_within ISO MGI:2182307 (PMID:14980704) RGD PMID:14980704 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2182351 (PMID:14980704)		 Ensembl
RGD		 PMID:14980704 GO_REF:0000107 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Duox1 dual oxidase 1 involved_in ISO
IEA		 UniProtKB:Q1HG43 (PMID:19339556), (PMID:22814254)
GO_REF:0000107		 RGD
Ensembl		 PMID:19339556 PMID:22814254 GO_REF:0000107 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 involved_in ISO UniProtKB:Q1HG44 (PMID:16651268), (PMID:19339556), (PMID:22814254), (PMID:25761904) RGD PMID:16651268 PMID:19339556 PMID:22814254 PMID:25761904 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within ISO MGI:1934143 (PMID:15258578) RGD PMID:15258578 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Sod1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA
ISS
IDA		 MGI:1857873 (PMID:14679182)
GO_REF:0000107
(PMID:15544046)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:14679182 PMID:15544046 PMID:15880490 PMID:12514262 PMID:10640619 GO_REF:0000024 GO_REF:0000107, RGD:1581090, RGD:634854, RGD:1601266 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 IDA RGD PMID:15642720 RGD:2291946 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16945374)		 Ensembl
RGD		 PMID:16945374 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Cat catalase acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA
IEA
IDA		 MGI:3051232|MGI:3053604 (PMID:10617683), (PMID:15178682), (PMID:17275685), (PMID:642030), (PMID:9600348)
GO_REF:0000033
GO_REF:0000043
(PMID:18379038)		 RGD
GO_Central
UniProt		 PMID:642030 PMID:9600348 PMID:10617683 PMID:15178682 PMID:17275685 More... GO_REF:0000033 GO_REF:0000043, RGD:1358492, RGD:2292202 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Duox1 dual oxidase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:15203190)
MGI:2158814|MGI:2388705|MGI:3589261 (PMID:10754271), (PMID:10915565), (PMID:11545230), (PMID:15182862), (PMID:15827346), (PMID:9788901)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:9788901 PMID:10754271 PMID:10915565 PMID:11545230 PMID:15182862 More... GO_REF:0000033 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:10617683)		 GO_Central
RGD		 PMID:10617683 GO_REF:0000033 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 involved_in ISO
IBA		 (PMID:19740759)
GO_REF:0000033		 RGD
GO_Central		 PMID:19740759 GO_REF:0000033 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hba-a3 hemoglobin alpha, adult chain 3 involved_in ISO
IBA		 (PMID:19740759)
GO_REF:0000033		 RGD
GO_Central		 PMID:19740759 GO_REF:0000033 NCBI chr10:15,311,637...15,312,481
Ensembl chr10:15,311,634...15,312,481 		JBrowse link
G Hbb hemoglobin subunit beta involved_in ISO
IBA		 (PMID:19740759)
GO_REF:0000033		 RGD
GO_Central		 PMID:19740759 GO_REF:0000033 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-bs hemoglobin, beta adult s chain involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:158,218,356...158,219,741
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbbl1 hemoglobin subunit beta like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:158,236,972...158,238,348
Ensembl chr 1:158,120,200...158,252,012
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbe1 hemoglobin subunit epsilon 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:158,282,931...158,458,855
Ensembl chr 1:158,282,936...158,284,391 		JBrowse link
G Hbe2 hemoglobin, epsilon 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:158,279,285...158,280,913
Ensembl chr 1:158,279,285...158,280,913 		JBrowse link
G Hbg1 hemoglobin subunit gamma 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425 		JBrowse link
G Hbq1b hemoglobin subunit theta 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:15,334,293...15,336,061
Ensembl chr10:15,320,762...15,321,397
Ensembl chr10:15,320,762...15,321,397 		JBrowse link
G Hbz hemoglobin subunit zeta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312 		JBrowse link
G Mpo myeloperoxidase involved_in
acts_upstream_of_or_within		 ISO (PMID:10772654)
MGI:2176344 (PMID:10085024)
(PMID:11907569)		 RGD PMID:10085024 PMID:10772654 PMID:11907569 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Prdx1 peroxiredoxin 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:18606987)
GO_REF:0000033
(PMID:11986303)		 RGD
GO_Central		 PMID:11986303 PMID:18606987 GO_REF:0000033 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx1l1 peroxiredoxin 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:193,602,142...193,603,085
Ensembl chr 2:193,602,121...193,603,084 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:2668456 (PMID:15902258)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:15902258 GO_REF:0000033 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prdx3 peroxiredoxin 3 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:18195003)
GO_REF:0000033
GO_REF:0000107
(PMID:7733872)		 RGD
GO_Central
Ensembl		 PMID:7733872 PMID:18195003 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
G Prdx4 peroxiredoxin 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066 		JBrowse link
G Prdx5 peroxiredoxin 5 involved_in ISO
IBA		 (PMID:10514471)
GO_REF:0000033		 RGD
GO_Central		 PMID:10514471 GO_REF:0000033 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Prdx6 peroxiredoxin 6 IDA RGD PMID:8641418 RGD:729495 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Pxdn peroxidasin involved_in ISO (PMID:18929642) RGD PMID:18929642 NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345 		JBrowse link
G Tpo thyroid peroxidase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IMP RGD PMID:10849437 RGD:634378 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cycs cytochrome c, somatic acts_upstream_of_or_within ISO (PMID:16757556) RGD PMID:16757556 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyct cytochrome c, testis acts_upstream_of_or_within ISO (PMID:16757556) RGD PMID:16757556 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158 		JBrowse link
G Duoxa1 dual oxidase maturation factor 1 acts_upstream_of_or_within ISO MGI:1914061 (PMID:23770197) RGD PMID:23770197 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 acts_upstream_of_or_within ISO MGI:2384861 (PMID:23770197) RGD PMID:23770197 NCBI chr 3:109,245,337...109,249,055
Ensembl chr 3:109,245,476...109,248,968 		JBrowse link
G Egfr epidermal growth factor receptor IEP RGD PMID:21258655 RGD:5131481 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Nox1 NADPH oxidase 1 involved_in ISO
IEA		 (PMID:11331784)
GO_REF:0000107		 RGD
Ensembl		 PMID:11331784 GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in
acts_upstream_of_or_within		 ISO (PMID:24567322)
MGI:3514165 (PMID:17766438)		 RGD PMID:17766438 PMID:24567322 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:15259009), (PMID:17325201) RGD PMID:15259009 PMID:17325201 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Sod2 superoxide dismutase 2 IMP RGD PMID:16716903 RGD:1580833 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
hypochlorous acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpo myeloperoxidase acts_upstream_of_or_within ISO MGI:2176344 (PMID:10085024) RGD PMID:10085024 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:26482480 RGD:12910938 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Cycs cytochrome c, somatic IMP RGD PMID:21410437 RGD:7349317 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649 		JBrowse link
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IMP RGD PMID:23590160 RGD:8694322 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
negative regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hp haptoglobin involved_in ISO (PMID:19740759) RGD PMID:19740759 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Mt3 metallothionein 3 IDA RGD PMID:12058024 RGD:625483 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
negative regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11991626 RGD:10003093 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
negative regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IMP PMID:31511561 UniProt PMID:31511561 RGD:126781736 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858 		JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3836690|PMID:18723473), (MGI:5464985|PMID:22521832), (MGI:5790173|PMID:25583114)		 UniProt
RGD		 PMID:18723473 PMID:22521832 PMID:25583114 GO_REF:0000024 MGI:3836690 MGI:5464985 MGI:5790173 NCBI chr  X:151,428,334...151,450,115
Ensembl chr  X:151,428,578...151,450,115 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3836690|PMID:18723473)		 UniProt
RGD		 PMID:18723473 GO_REF:0000024 MGI:3836690 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Adcy10 adenylate cyclase 10 IMP RGD PMID:32664470 RGD:329347825 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 IMP RGD PMID:22209705 RGD:13800744 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:18292530 RGD:11341712 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Coa8 cytochrome c oxidase assembly factor 8 involved_in ISO
ISS		 (PMID:25175347)
GO_REF:0000024		 RGD
UniProt		 PMID:25175347 GO_REF:0000024 NCBI chr 6:130,772,218...130,797,081
Ensembl chr 6:130,771,199...130,797,081 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:26482480 RGD:12910938 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 IMP RGD PMID:23041468 RGD:10401126 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Hbp1 HMG-box transcription factor 1 involved_in ISO (MGI:5754467|PMID:24675724) RGD PMID:24675724 MGI:5754467 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:26071548 RGD:401793712 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IMP RGD PMID:22547655 RGD:10402548 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Ins2 insulin 2 involved_in ISO ComplexPortal:CPX-1134 (PMID:19188609) RGD PMID:19188609 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:28483668 RGD:12910717 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir140 microRNA 140 IMP RGD PMID:32519270 RGD:329347827 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO (PMID:23516523) RGD PMID:23516523 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 IMP RGD PMID:26888427 RGD:11040458 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5908331|PMID:22611253)		 UniProt
RGD		 PMID:22611253 GO_REF:0000024 MGI:5908331 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:24096089 RGD:10413842 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgr1 prostaglandin reductase 1 IDA RGD PMID:9667737 RGD:401959219 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO (MGI:5640904|PMID:25398325) RGD PMID:25398325 MGI:5640904 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:23422569 RGD:9585767 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
negative regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q61221 (MGI:3796473|PMID:18281291)		 Ensembl
RGD		 PMID:18281291 GO_REF:0000107 MGI:3796473 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IEA		 UniProtKB:Q61221 (MGI:3796473|PMID:18281291)
GO_REF:0000107		 RGD
Ensembl		 PMID:18281291 GO_REF:0000107 MGI:3796473 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:2154396 (PMID:7889565) RGD PMID:7889565 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Becn1 beclin 1 involved_in ISO UniProtKB:Q61221 (MGI:3796473|PMID:18281291) RGD PMID:18281291 MGI:3796473 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 involved_in ISO (MGI:5315337|PMID:21052097) RGD PMID:21052097 MGI:5315337 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO UniProtKB:Q61221 (MGI:3796473|PMID:18281291) RGD PMID:18281291 MGI:3796473 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA		 (PMID:23415688)
GO_REF:0000107		 RGD
Ensembl		 PMID:23415688 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Cryab crystallin, alpha B IDA RGD PMID:15358243 RGD:1598485 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:23608653 RGD:7364951 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA
ISO		 GO_REF:0000107
(MGI:3796473|PMID:18281291)		 Ensembl
RGD		 PMID:18281291 GO_REF:0000107 MGI:3796473 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk2 hexokinase 2 involved_in ISO (MGI:5619449|PMID:22517678) RGD PMID:22517678 MGI:5619449 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (MGI:5315337|PMID:21052097) RGD PMID:21052097 MGI:5315337 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Mmp3 matrix metallopeptidase 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20969476)		 Ensembl
RGD		 PMID:20969476 GO_REF:0000107 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor involved_in ISO
IEA		 (MGI:5050076|PMID:17357786)
GO_REF:0000107		 RGD
Ensembl		 PMID:17357786 GO_REF:0000107 MGI:5050076 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17357786)		 UniProt
RGD		 PMID:17357786 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:18560593) RGD PMID:18560593 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5440401|PMID:22532565)		 UniProt
RGD		 PMID:22532565 GO_REF:0000024 MGI:5440401 NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS		 UniProtKB:Q9H4P4 (PMID:18541373)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:18541373 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5572869|PMID:17521387)		 UniProt
Ensembl
RGD		 PMID:17521387 GO_REF:0000024 GO_REF:0000107 MGI:5572869 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt3 sirtuin 3 IMP RGD PMID:23397292 RGD:9586042 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Sirt5 sirtuin 5 involved_in ISO (PMID:24140062) RGD PMID:24140062 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:20066163)		 UniProt
RGD		 PMID:20066163 GO_REF:0000024 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO MGI:5319187 (PMID:22044588) RGD PMID:22044588 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857263 (PMID:22044588)		 Ensembl
RGD		 PMID:22044588 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO
IEA		 (MGI:5689082|PMID:25470454)
GO_REF:0000107		 RGD
Ensembl		 PMID:25470454 GO_REF:0000107 MGI:5689082 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
negative regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180086 (PMID:11168643)		 Ensembl
RGD		 PMID:11168643 GO_REF:0000107 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IMP RGD PMID:24601882 RGD:39128160 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Crp C-reactive protein IDA RGD PMID:9767445 RGD:9586000 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Pon3 paraoxonase 3 involved_in ISO
IEA		 (MGI:5543365|PMID:22441669)
GO_REF:0000107		 RGD
Ensembl		 PMID:22441669 GO_REF:0000107 MGI:5543365 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa1 dual oxidase maturation factor 1 involved_in ISO (PMID:22814254) RGD PMID:22814254 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 involved_in ISO (PMID:16651268), (PMID:22814254) RGD PMID:16651268 PMID:22814254 NCBI chr 3:109,245,337...109,249,055
Ensembl chr 3:109,245,476...109,248,968 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:27997345 RGD:12910740 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Nox4 NADPH oxidase 4 IMP RGD PMID:27279484 RGD:151347625 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Sod2 superoxide dismutase 2 IMP RGD PMID:20529999 RGD:27095884 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:12,615,455...12,623,615
Ensembl chr10:12,615,190...12,623,615 		JBrowse link
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nnt nicotinamide nucleotide transhydrogenase IMP RGD PMID:24722990 RGD:13513981 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:23507046)
GO_REF:0000107		 RGD
Ensembl		 PMID:23507046 GO_REF:0000107 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
positive regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in ISO
IEA		 (PMID:26838550)
GO_REF:0000107		 RGD
Ensembl		 PMID:26838550 GO_REF:0000107 NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15450084 RGD:2313867 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Cd36 CD36 molecule involved_in ISO
IEA		 (MGI:4438693|PMID:20037584)
GO_REF:0000107		 RGD
Ensembl		 PMID:20037584 GO_REF:0000107 MGI:4438693 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2447864 (PMID:16522634)		 Ensembl
RGD		 PMID:16522634 GO_REF:0000107 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119 		JBrowse link
G Cyba cytochrome b-245 alpha chain involved_in ISO
IEA		 (PMID:22423966)
GO_REF:0000107		 RGD
Ensembl		 PMID:22423966 GO_REF:0000107 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Foxo3 forkhead box O3 IMP RGD PMID:24278276 RGD:10402204 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in IGI PMID:17308309 ARUK-UCL PMID:17308309 RGD:12910994 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Il4 interleukin 4 IDA RGD PMID:24073824 RGD:10402792 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:27997345 RGD:12910740 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir24-2 microRNA 24-2 involved_in ISO (PMID:21788589) RGD PMID:21788589 NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase IMP RGD PMID:21712532 RGD:9590189 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) RGD PMID:22555455 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5300086|PMID:22041900)
GO_REF:0000107		 RGD
Ensembl		 PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family involved_in ISO (PMID:24404184) RGD PMID:24404184 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 acts_upstream_of_or_within ISO (MGI:6414721|PMID:28128227) RGD PMID:28128227 MGI:6414721 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISO
IEA		 (MGI:4438693|PMID:20037584)
GO_REF:0000107		 RGD
Ensembl		 PMID:20037584 GO_REF:0000107 MGI:4438693 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) RGD PMID:20037584 MGI:4438693 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
positive regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:19885844 RGD:7244243 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cd36 CD36 molecule involved_in ISO (MGI:4850200|PMID:20978343) RGD PMID:20978343 MGI:4850200 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:20160708) RGD PMID:20160708 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IMP RGD PMID:20439821 RGD:7829726 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Dhrs4 dehydrogenase/reductase 4 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Duoxa1 dual oxidase maturation factor 1 acts_upstream_of_or_within ISO MGI:2139422 (PMID:20233719) RGD PMID:20233719 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A IMP RGD PMID:20930373 RGD:10395362 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA
ISO		 GO_REF:0000107
(PMID:17275676)		 Ensembl
RGD		 PMID:17275676 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:20160708)		 Ensembl
RGD		 PMID:20160708 GO_REF:0000107 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Lcn2 lipocalin 2 IMP RGD PMID:30574656 RGD:126781752 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lep leptin IDA RGD PMID:20738325 RGD:8693628 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (MGI:4850200|PMID:20978343) RGD PMID:20978343 MGI:4850200 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nox1 NADPH oxidase 1 IMP RGD PMID:16254042 RGD:1581408 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nox4 NADPH oxidase 4 IMP RGD PMID:15848200 RGD:2324674 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 IMP RGD PMID:23554738 RGD:11073697 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20969476)
GO_REF:0000107		 ParkinsonsUK-UCL
RGD
Ensembl		 PMID:20969476 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19019919)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19019919 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:5284758|PMID:19019919)		 UniProt
RGD		 PMID:19019919 GO_REF:0000024 MGI:5284758 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) RGD PMID:20165904 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Plau plasminogen activator, urokinase IDA RGD PMID:16456094 RGD:6484217 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15158121 RGD:1642626 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in
acts_upstream_of_or_within		 ISO (MGI:5315337|PMID:21052097)
(PMID:19498109)		 RGD PMID:19498109 PMID:21052097 MGI:5315337 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO (PMID:18541373) RGD PMID:18541373 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511 		JBrowse link
G Romo1 reactive oxygen species modulator 1 involved_in ISO (PMID:16842742) RGD PMID:16842742 NCBI chr 3:144,659,709...144,661,310
Ensembl chr 3:144,659,826...144,661,310 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18757424) RGD PMID:18757424 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tspo translocator protein involved_in IDA
ISO		 (MGI:5689082|PMID:25470454) RGD PMID:25470454 PMID:12437594 MGI:5689082, RGD:2317161 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Xdh xanthine dehydrogenase involved_in IEA
ISO		 GO_REF:0000107
(PMID:18386220)		 Ensembl
RGD		 PMID:18386220 GO_REF:0000107 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO (PMID:22739135) RGD PMID:22739135 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
positive regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:21376054 RGD:5129173 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:21076237 RGD:5129195 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:O88536 (PMID:11316806) RGD PMID:11316806 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Cd177 CD177 molecule involved_in ISO UniProtKB:P05107|UniProtKB:P11215 (PMID:21193407) RGD PMID:21193407 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19358895) RGD PMID:19358895 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Crp C-reactive protein involved_in ISO (PMID:24141169) RGD PMID:24141169 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5586806|PMID:10725737)		 Ensembl
RGD		 PMID:10725737 GO_REF:0000107 MGI:5586806 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cyba cytochrome b-245 alpha chain IMP RGD PMID:15036821 RGD:8693734 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:22966991 RGD:7204494 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IMP RGD PMID:26682942 RGD:329961560 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS		 (PMID:11714832)
GO_REF:0000024		 RGD
UniProt		 PMID:11714832 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in ISO UniProtKB:P05067-PRO_0000000092 (MGI:5905278|PMID:11316806) RGD PMID:11316806 MGI:5905278 NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009187|PMID:11408560)		 BHF-UCL
RGD		 PMID:11408560 GO_REF:0000024 MGI:5009187 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:24935944 RGD:14985214 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Il18 interleukin 18 IMP RGD PMID:19497959 RGD:4889403 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO UniProtKB:P05107|UniProtKB:Q8N6Q3 (PMID:21193407)
(MGI:3812233|PMID:18685038), (MGI:3814938|PMID:18981141)		 RGD PMID:18685038 PMID:18981141 PMID:21193407 MGI:3812233 MGI:3814938 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb2 integrin subunit beta 2 involved_in ISO UniProtKB:P11215|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Mapt microtubule-associated protein tau involved_in ISO (PMID:22920254) RGD PMID:22920254 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Nox1 NADPH oxidase 1 IMP RGD PMID:24294978 PMID:26682942 RGD:329955573, RGD:329961560 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 involved_in ISO (PMID:24141169) RGD PMID:24141169 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA
ISS		 (PMID:19801500)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19801500 GO_REF:0000024 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
IEA		 (PMID:18219391)
GO_REF:0000107		 RGD
Ensembl		 PMID:18219391 GO_REF:0000107 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:19358895)
GO_REF:0000107		 RGD
Ensembl		 PMID:19358895 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:22073128)
GO_REF:0000024		 RGD
UniProt		 PMID:22073128 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:3812233|PMID:18685038) RGD PMID:18685038 MGI:3812233 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 acts_upstream_of_or_within ISO MGI:2155916 (PMID:20935152) RGD PMID:20935152 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G Ahr aryl hydrocarbon receptor IMP RGD PMID:35788946 RGD:401793705 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Dmd dystrophin acts_upstream_of_or_within ISO MGI:1856328 (PMID:20716577) RGD PMID:20716577 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Gbf1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 involved_in ISO (PMID:22573891) RGD PMID:22573891 NCBI chr 1:245,018,535...245,147,052
Ensembl chr 1:245,018,568...245,147,042 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Lipa lipase A, lysosomal acid type involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2451080 (PMID:24287405)		 Ensembl
RGD		 PMID:24287405 GO_REF:0000107 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 IMP RGD PMID:21275845 RGD:41404729 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insr insulin receptor IDA in cerebellar granule neurons RGD PMID:17919343 RGD:2290474 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Noxa1 NADPH oxidase activator 1 involved_in ISO (PMID:16636067) RGD PMID:16636067 NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (MGI:5558956|PMID:24553947) RGD PMID:24553947 MGI:5558956 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2668456 (PMID:17325201)		 Ensembl
RGD		 PMID:17325201 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:26210919)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26210919 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5810834|PMID:27214549)		 Ensembl
RGD		 PMID:27214549 GO_REF:0000107 MGI:5810834 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Ccn6 cellular communication network factor 6 involved_in ISO (PMID:27252383) RGD PMID:27252383 NCBI chr20:42,569,309...42,585,126
Ensembl chr20:42,569,309...42,585,126 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 involved_in ISO (PMID:30478045)
(MGI:6843609|PMID:24415791)		 RGD PMID:24415791 PMID:30478045 MGI:6843609 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IMP RGD PMID:27279484 RGD:151347625 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in ISO
IBA		 (PMID:28779020)
GO_REF:0000033
(MGI:6103777|PMID:28779020)		 RGD
GO_Central		 PMID:28779020 GO_REF:0000033 MGI:6103777 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868 		JBrowse link
G Slc25a33 solute carrier family 25 member 33 involved_in ISO (PMID:20453889) RGD PMID:20453889 NCBI chr 5:160,195,040...160,219,961
Ensembl chr 5:160,195,042...160,219,961 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:5641585|PMID:25637806) RGD PMID:25637806 MGI:5641585 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Ucp1 uncoupling protein 1 involved_in NAS
ISO		 PMID:20416274
(MGI:4837058|PMID:20416274)		 RGD PMID:20416274 PMID:20416274 MGI:4837058, RGD:11541111 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Arf4 ADP-ribosylation factor 4 involved_in ISO
IEA		 (PMID:19041174)
GO_REF:0000107		 RGD
Ensembl		 PMID:19041174 GO_REF:0000107 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Atg5 autophagy related 5 acts_upstream_of_or_within ISO MGI:3663625 (PMID:24185898) RGD PMID:24185898 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Bco2 beta-carotene oxygenase 2 involved_in ISO (MGI:4947204|PMID:21106934) RGD PMID:21106934 MGI:4947204 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase involved_in ISO
IBA		 (PMID:25961505)
GO_REF:0000033		 RGD
GO_Central		 PMID:25961505 GO_REF:0000033 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3829820|PMID:19005183)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19005183 GO_REF:0000024 GO_REF:0000107 MGI:3829820 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5780495|PMID:26391622)		 UniProt
RGD		 PMID:26391622 GO_REF:0000024 MGI:5780495 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:19696738)
GO_REF:0000107		 RGD
Ensembl		 PMID:19696738 GO_REF:0000107 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo1 forkhead box O1 acts_upstream_of_or_within ISO MGI:1890081 (PMID:19896444) RGD PMID:19896444 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO MGI:1890077 (PMID:19896444) RGD PMID:19896444 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:19096392) RGD PMID:19096392 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:24576675) RGD PMID:24576675 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:22836756) RGD PMID:22836756 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mpv17 mitochondrial inner membrane protein MPV17 involved_in ISO (MGI:3776221|PMID:16041630) RGD PMID:16041630 MGI:3776221 NCBI chr 6:25,221,668...25,236,241
Ensembl chr 6:25,222,896...25,236,244 		JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:19457114 RGD:5508731 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:21138942)		 ParkinsonsUK-UCL
RGD		 PMID:21138942 GO_REF:0000024 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) RGD PMID:22865452 NCBI chr  X:58,486,699...58,553,533
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO
IBA		 (MGI:5306739|PMID:21080215)
GO_REF:0000033		 RGD
GO_Central		 PMID:21080215 GO_REF:0000033 MGI:5306739 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO UniProtKB:Q9UL15 (PMID:21138942), (PMID:24475098) RGD PMID:21138942 PMID:24475098 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prcp prolylcarboxypeptidase acts_upstream_of_or_within ISO MGI:4123993 (PMID:21297000) RGD PMID:21297000 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:18541373) RGD PMID:18541373 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO (PMID:18541373) RGD PMID:18541373 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511 		JBrowse link
G Snca synuclein alpha involved_in ISO (MGI:5585658|PMID:25043722) RGD PMID:25043722 MGI:5585658 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in		 ISO (PMID:21052097)
(PMID:22836756)		 RGD PMID:21052097 PMID:22836756 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO MGI:3706236 (PMID:22513871) RGD PMID:22513871 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056 		JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO
IEA		 (MGI:4850200|PMID:20978343)
GO_REF:0000107		 RGD
Ensembl		 PMID:20978343 GO_REF:0000107 MGI:4850200 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Dhfr dihydrofolate reductase involved_in ISO (MGI:5645206|PMID:19666465) RGD PMID:19666465 MGI:5645206 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Fbln5 fibulin 5 involved_in ISO (MGI:3610795|PMID:15528465) RGD PMID:15528465 MGI:3610795 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:19666465) RGD PMID:19666465 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (MGI:4850200|PMID:20978343) RGD PMID:20978343 MGI:4850200 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syk spleen associated tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:4414596|PMID:19797524)		 UniProt
RGD		 PMID:19797524 GO_REF:0000024 MGI:4414596 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
regulation of superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir27b microRNA 27b involved_in ISO UniProtKB:P29353-1 (PMID:24177325) RGD PMID:24177325 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Shc1 SHC adaptor protein 1 involved_in ISO RNAcentral:URS000059311D_9606 (PMID:24177325) RGD PMID:24177325 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa4 apolipoprotein A4 involved_in ISO
IEA		 (PMID:16945374)
GO_REF:0000107		 RGD
Ensembl		 PMID:16945374 GO_REF:0000107 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856097 (PMID:16371425) RGD PMID:16371425 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Ccs copper chaperone for superoxide dismutase involved_in IEA
IBA		 GO_REF:0000108
GO_REF:0000033		 GOC
GO_Central		 GO_REF:0000033 GO_REF:0000108 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915 		JBrowse link
G Cygb cytoglobin involved_in ISS
ISO		 GO_REF:0000024
(MGI:7581086|PMID:34930834)
(PMID:34930834)		 UniProt
RGD		 PMID:34930834 GO_REF:0000024 MGI:7581086 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442 		JBrowse link
G Fancc FA complementation group C involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98351 (PMID:11493445)		 Ensembl
RGD		 PMID:11493445 GO_REF:0000107 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376 		JBrowse link
G Mb myoglobin involved_in ISS
ISO		 GO_REF:0000024
(PMID:34679218)		 UniProt
RGD		 PMID:34679218 GO_REF:0000024 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mpo myeloperoxidase acts_upstream_of_or_within ISO MGI:2176344 (PMID:10085024) RGD PMID:10085024 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12383939)		 UniProt
RGD		 PMID:12383939 GO_REF:0000024 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19666465)		 Ensembl
RGD		 PMID:19666465 GO_REF:0000107 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15102952)		 UniProt
RGD		 PMID:15102952 GO_REF:0000024 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Prdx1 peroxiredoxin 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3611932 (PMID:16170382), (PMID:16880205)		 GO_Central
RGD		 PMID:16170382 PMID:16880205 GO_REF:0000033 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx1l1 peroxiredoxin 1-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:193,602,142...193,603,085
Ensembl chr 2:193,602,121...193,603,084 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(MGI:4850200|PMID:20978343)
(PMID:20978343)		 Ensembl
GO_Central
RGD		 PMID:20978343 GO_REF:0000033 GO_REF:0000107 MGI:4850200 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in
acts_upstream_of_or_within		 TAS
IBA
ISO
IEA
ISS
IMP
IDA		 GO_REF:0000033
MGI:1857872|MGI:1857873|MGI:2387861|MGI:3526701|MGI:95480 (PMID:10436316), (PMID:10471451), (PMID:10679476), (PMID:11493445), (PMID:12433839), (PMID:17448893), (PMID:8673102), (PMID:9516486), (PMID:9788901)
GO_REF:0000108
GO_REF:0000024		 GO_Central
RGD
GOC
UniProt		 PMID:8673102 PMID:9516486 PMID:9788901 PMID:10436316 PMID:10471451 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000108, RGD:730094, RGD:8655968, RGD:634854, RGD:1601266 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within
involved_in		 IDA
ISO		 MGI:1857129|MGI:1857480 (PMID:16873728)
(PMID:16179351)		 RGD PMID:16179351 PMID:16873728 PMID:12107766 PMID:19439219 PMID:15642720 RGD:2291939, RGD:2317387, RGD:2291946 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2180086 (PMID:11168643)		 Ensembl
RGD		 PMID:11168643 GO_REF:0000107 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Cyba cytochrome b-245 alpha chain involved_in ISO
IBA
IEA
IMP		 (PMID:2243141)
GO_REF:0000033
GO_REF:0000107
PMID:8798532		 RGD
GO_Central
Ensembl		 PMID:2243141 PMID:8798532 GO_REF:0000033 GO_REF:0000107, RGD:2317869 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain involved_in ISO
IBA		 (PMID:12042318)
GO_REF:0000033		 RGD
GO_Central		 PMID:12042318 GO_REF:0000033 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Duox1 dual oxidase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 involved_in ISO
IBA		 UniProtKB:Q1HG43 (PMID:22814254)
GO_REF:0000033		 RGD
GO_Central		 PMID:22814254 GO_REF:0000033 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Edn1 endothelin 1 IDA RGD PMID:16788136 RGD:4892602 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within_positive_effect
involved_in		 ISO
IBA		 (PMID:2547247)
MGI:1934143 (PMID:10725280), (PMID:11156938)
GO_REF:0000033		 RGD
GO_Central		 PMID:2547247 PMID:10725280 PMID:11156938 GO_REF:0000033 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:8280052)
(PMID:9490028)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:8280052 PMID:9490028 GO_REF:0000033 GO_REF:0000107 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 involved_in ISO
IBA		 (PMID:8280052)
GO_REF:0000033		 RGD
GO_Central		 PMID:8280052 GO_REF:0000033 NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389 		JBrowse link
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IMP		 GO_REF:0000107
MGI:3616995 (PMID:18397177)
GO_REF:0000033
PMID:10485709
(PMID:10485709), (PMID:18023288)		 Ensembl
RGD
GO_Central		 PMID:10485709 PMID:18023288 PMID:18397177 PMID:10485709 GO_REF:0000033 GO_REF:0000107, RGD:633401 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nox3 NADPH oxidase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:44,238,012...44,302,851
Ensembl chr 1:44,236,992...44,302,851 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:3694159|PMID:10869423)		 UniProt
GO_Central
Ensembl
RGD		 PMID:10869423 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3694159 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Noxa1 NADPH oxidase activator 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967 		JBrowse link
G Noxo1 NADPH oxidase organizer 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:13,723,253...13,726,008
Ensembl chr10:13,721,473...13,726,061 		JBrowse link
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 involved_in ISO (PMID:10318872) RGD PMID:10318872 NCBI chr 3:70,071,970...70,078,103
Ensembl chr 3:70,072,497...70,078,102 		JBrowse link
G Sh3pxd2a SH3 and PX domains 2A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166 		JBrowse link
G Sod1 superoxide dismutase 1 acts_upstream_of_or_within ISO (PMID:15317809) RGD PMID:15317809 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857344|MGI:1857480|MGI:2447406|MGI:2679331 (PMID:10212301), (PMID:15781740), (PMID:16677818) RGD PMID:10212301 PMID:15781740 PMID:16677818 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tafa4 TAFA chemokine like family member 4 involved_in ISO (MGI:6282963|PMID:25109685) RGD PMID:25109685 MGI:6282963 NCBI chr 4:129,437,466...129,671,320
Ensembl chr 4:129,437,467...129,671,249 		JBrowse link
superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta synthase acts_upstream_of_or_within ISO MGI:1857139 (PMID:10953023) RGD PMID:10953023 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccs copper chaperone for superoxide dismutase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915 		JBrowse link
G Cyb5r4 cytochrome b5 reductase 4 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:10611283)		 Ensembl
GO_Central
RGD		 PMID:10611283 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:87,975,596...88,048,356
Ensembl chr 8:87,981,116...88,045,832 		JBrowse link
G Cyba cytochrome b-245 alpha chain involved_in IDA
ISO
IMP		 (PMID:1763037), (PMID:2243141)
PMID:8798532		 RGD PMID:1763037 PMID:2243141 PMID:15322091 PMID:8798532 PMID:8798532 RGD:1580287, RGD:2317869, RGD:2317869 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain involved_in ISO (PMID:12042318)
(MGI:5568138|PMID:24739962)		 RGD PMID:12042318 PMID:24739962 MGI:5568138 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 acts_upstream_of_or_within ISO MGI:3765965 (PMID:21824519) RGD PMID:21824519 NCBI chr 6:58,070,035...58,970,165
Ensembl chr 6:58,070,283...58,969,840 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:19409882) RGD PMID:19409882 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 GO_REF:0000107
MGI:1857228 (PMID:12933833)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12933833 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in IDA
ISO
IMP		 (PMID:18760347) RGD PMID:18760347 PMID:15322091 PMID:15322091 RGD:1580287, RGD:1580287 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Noxa1 NADPH oxidase activator 1 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:20609497)
(PMID:12473664)
GO_REF:0000024		 RGD
UniProt		 PMID:12473664 PMID:20609497 GO_REF:0000024 NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967 		JBrowse link
G Noxo1 NADPH oxidase organizer 1 acts_upstream_of_or_within ISO (PMID:12473664) RGD PMID:12473664 NCBI chr10:13,723,253...13,726,008
Ensembl chr10:13,721,473...13,726,061 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IMP RGD PMID:17901563 RGD:5133248 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrros negative regulator of reactive oxygen species NOT|involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6192878|PMID:29909984)
(MGI:5568138|PMID:24739962)		 UniProt
Ensembl
RGD		 PMID:24739962 PMID:29909984 GO_REF:0000024 GO_REF:0000107 MGI:5568138 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142 		JBrowse link
G Sh3pxd2a SH3 and PX domains 2A involved_in ISO (PMID:19755710), (PMID:20609497) RGD PMID:19755710 PMID:20609497 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B involved_in ISO (PMID:19755710) RGD PMID:19755710 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 involved_in ISO (PMID:27040821) RGD PMID:27040821 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Sod1 superoxide dismutase 1 acts_upstream_of_or_within
involved_in		 TAS
ISO
ISS
IDA		 MGI:1857872 (PMID:11404260)
(PMID:12551919)
GO_REF:0000024		 RGD
UniProt		 PMID:11404260 PMID:12551919 PMID:2703531 PMID:12514262 PMID:10640619 GO_REF:0000024, RGD:730094, RGD:634854, RGD:1601266 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in
acts_upstream_of_or_within		 ISO
ISS		 (PMID:12551919), (PMID:14980699)
MGI:1857344|MGI:1857480|MGI:2176435|MGI:2447406 (PMID:10049502), (PMID:12176043), (PMID:15637112)
GO_REF:0000024		 RGD
UniProt		 PMID:10049502 PMID:12176043 PMID:12551919 PMID:14980699 PMID:15637112 GO_REF:0000024 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      cellular metabolic process 9554
        reactive oxygen species metabolic process 267
          hydrogen peroxide metabolic process + 61
          hypochlorous acid metabolic process + 1
          negative regulation of reactive oxygen species metabolic process + 60
          positive regulation of reactive oxygen species metabolic process + 85
          reactive oxygen species biosynthetic process + 75
          regulation of reactive oxygen species metabolic process + 174
          superoxide metabolic process + 74
paths to the root