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Gene: Coa8 (cytochrome c oxidase assembly factor 8) Rattus norvegicus
Symbol: Coa8
Name: cytochrome c oxidase assembly factor 8
Description: Predicted to be involved in several processes, including mitochondrial respiratory chain complex IV assembly; positive regulation of apoptotic process; and positive regulation of cytochrome-c oxidase activity. Predicted to localize to the matrix side of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COA8 (cytochrome c oxidase assembly factor 8); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: APOP-1; Apop1; Apopt1; apoptogenic 1; apoptogenic 1, mitochondrial; apoptogenic protein 1, mitochondrial; LOC299341; MGC124853; RGD1304719; similar to RIKEN cDNA 2810002N01; UPF0671 protein C14orf153 homolog
Homo sapiens (human) : COA8 (cytochrome c oxidase assembly factor 8)  HGNC  Alliance
Mus musculus (house mouse) : Coa8 (cytochrome c oxidase assembly factor 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apopt1 (apoptogenic 1, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : APOPT1 (apoptogenic 1, mitochondrial)
Canis lupus familiaris (dog) : COA8 (cytochrome c oxidase assembly factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apopt1 (apoptogenic 1, mitochondrial)
Sus scrofa (pig) : APOPT1 (apoptogenic 1, mitochondrial)
Chlorocebus sabaeus (African green monkey) : APOPT1 (apoptogenic 1, mitochondrial)
Heterocephalus glaber (naked mole-rat) : Apopt1 (apoptogenic 1, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06136,279,476 - 136,304,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.06136,185,772 - 136,210,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,185,487 - 136,210,940 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,279,496 - 136,304,095 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,205,803 - 144,230,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,495,214 - 136,520,116 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16136,501,406 - 136,526,300 (+)NCBI
Celera6128,327,965 - 128,352,225 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Coa8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304719
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.