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Gene: Coa8 (cytochrome c oxidase assembly factor 8) Rattus norvegicus
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Symbol: Coa8
Name: cytochrome c oxidase assembly factor 8
Description: Predicted to be involved in several processes, including mitochondrial respiratory chain complex IV assembly; positive regulation of apoptotic process; and positive regulation of cytochrome-c oxidase activity. Predicted to localize to the matrix side of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COA8 (cytochrome c oxidase assembly factor 8); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: APOP-1; Apop1; Apopt1; apoptogenic 1; apoptogenic 1, mitochondrial; apoptogenic protein 1, mitochondrial; LOC299341; MGC124853; RGD1304719; similar to RIKEN cDNA 2810002N01; UPF0671 protein C14orf153 homolog
Orthologs:
Homo sapiens (human) : COA8 (cytochrome c oxidase assembly factor 8)  HGNC  Alliance
Mus musculus (house mouse) : Coa8 (cytochrome c oxidase assembly factor 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apopt1 (apoptogenic 1, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : APOPT1 (apoptogenic 1, mitochondrial)
Canis lupus familiaris (dog) : COA8 (cytochrome c oxidase assembly factor 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apopt1 (apoptogenic 1, mitochondrial)
Sus scrofa (pig) : APOPT1 (apoptogenic 1, mitochondrial)
Chlorocebus sabaeus (African green monkey) : APOPT1 (apoptogenic 1, mitochondrial)
Heterocephalus glaber (naked mole-rat) : Apopt1 (apoptogenic 1, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06136,279,476 - 136,304,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.06136,185,772 - 136,210,936 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,185,487 - 136,210,940 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6136,279,496 - 136,304,095 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,205,803 - 144,230,967 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46136,495,214 - 136,520,116 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16136,501,406 - 136,526,300 (+)NCBI
Celera6128,327,965 - 128,352,225 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Coa8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304719
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.