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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of reactive oxygen species metabolic process
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Accession:GO:2000377 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.
Synonyms:exact_synonym: regulation of ROS metabolic process;   regulation of reactive oxygen species metabolism


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regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Arf4 ADP-ribosylation factor 4 involved_in ISO
IEA		 (PMID:19041174)
GO_REF:0000107		 RGD
Ensembl		 PMID:19041174 GO_REF:0000107 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261 		JBrowse link
G Atg5 autophagy related 5 acts_upstream_of_or_within ISO MGI:3663625 (PMID:24185898) RGD PMID:24185898 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Bco2 beta-carotene oxygenase 2 involved_in ISO (MGI:4947204|PMID:21106934) RGD PMID:21106934 MGI:4947204 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase involved_in ISO
IBA		 (PMID:25961505)
GO_REF:0000033		 RGD
GO_Central		 PMID:25961505 GO_REF:0000033 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3829820|PMID:19005183)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19005183 GO_REF:0000024 GO_REF:0000107 MGI:3829820 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5780495|PMID:26391622)		 UniProt
RGD		 PMID:26391622 GO_REF:0000024 MGI:5780495 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:19696738)
GO_REF:0000107		 RGD
Ensembl		 PMID:19696738 GO_REF:0000107 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo1 forkhead box O1 acts_upstream_of_or_within ISO MGI:1890081 (PMID:19896444) RGD PMID:19896444 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO MGI:1890077 (PMID:19896444) RGD PMID:19896444 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:19096392) RGD PMID:19096392 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:24576675) RGD PMID:24576675 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:22836756) RGD PMID:22836756 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mpv17 mitochondrial inner membrane protein MPV17 involved_in ISO (MGI:3776221|PMID:16041630) RGD PMID:16041630 MGI:3776221 NCBI chr 6:25,221,668...25,236,241
Ensembl chr 6:25,222,896...25,236,244 		JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:19457114 RGD:5508731 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:21138942)		 ParkinsonsUK-UCL
RGD		 PMID:21138942 GO_REF:0000024 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 involved_in ISO (PMID:22865452) RGD PMID:22865452 NCBI chr  X:58,486,699...58,553,533
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO
IBA		 (MGI:5306739|PMID:21080215)
GO_REF:0000033		 RGD
GO_Central		 PMID:21080215 GO_REF:0000033 MGI:5306739 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO UniProtKB:Q9UL15 (PMID:21138942), (PMID:24475098) RGD PMID:21138942 PMID:24475098 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prcp prolylcarboxypeptidase acts_upstream_of_or_within ISO MGI:4123993 (PMID:21297000) RGD PMID:21297000 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:18541373) RGD PMID:18541373 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (PMID:21052097) RGD PMID:21052097 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO (PMID:18541373) RGD PMID:18541373 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511 		JBrowse link
G Snca synuclein alpha involved_in ISO (MGI:5585658|PMID:25043722) RGD PMID:25043722 MGI:5585658 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within
involved_in		 ISO (PMID:21052097)
(PMID:22836756)		 RGD PMID:21052097 PMID:22836756 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO MGI:3706236 (PMID:22513871) RGD PMID:22513871 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056 		JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:26482480 RGD:12910938 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Cycs cytochrome c, somatic IMP RGD PMID:21410437 RGD:7349317 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:1,988,451...2,025,300
Ensembl chr10:1,988,136...2,007,649 		JBrowse link
G Prl prolactin involved_in ISO (PMID:24530842) RGD PMID:24530842 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IMP RGD PMID:23590160 RGD:8694322 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
negative regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hp haptoglobin involved_in ISO (PMID:19740759) RGD PMID:19740759 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Mt3 metallothionein 3 IDA RGD PMID:12058024 RGD:625483 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
negative regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11991626 RGD:10003093 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
negative regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb7 ATP binding cassette subfamily B member 7 involved_in IMP PMID:31511561 UniProt PMID:31511561 RGD:126781736 NCBI chr  X:69,295,598...69,436,775
Ensembl chr  X:69,295,552...69,436,858 		JBrowse link
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3836690|PMID:18723473), (MGI:5464985|PMID:22521832), (MGI:5790173|PMID:25583114)		 UniProt
RGD		 PMID:18723473 PMID:22521832 PMID:25583114 GO_REF:0000024 MGI:3836690 MGI:5464985 MGI:5790173 NCBI chr  X:151,428,334...151,450,115
Ensembl chr  X:151,428,578...151,450,115 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3836690|PMID:18723473)		 UniProt
RGD		 PMID:18723473 GO_REF:0000024 MGI:3836690 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642 		JBrowse link
G Adcy10 adenylate cyclase 10 IMP RGD PMID:32664470 RGD:329347825 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 IMP RGD PMID:22209705 RGD:13800744 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:18292530 RGD:11341712 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Coa8 cytochrome c oxidase assembly factor 8 involved_in ISO
ISS		 (PMID:25175347)
GO_REF:0000024		 RGD
UniProt		 PMID:25175347 GO_REF:0000024 NCBI chr 6:130,772,218...130,797,081
Ensembl chr 6:130,771,199...130,797,081 		JBrowse link
G Ctns cystinosin, lysosomal cystine transporter IMP RGD PMID:26482480 RGD:12910938 NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 IMP RGD PMID:23041468 RGD:10401126 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Hbp1 HMG-box transcription factor 1 involved_in ISO (MGI:5754467|PMID:24675724) RGD PMID:24675724 MGI:5754467 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:26071548 RGD:401793712 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IMP RGD PMID:22547655 RGD:10402548 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Ins2 insulin 2 involved_in ISO ComplexPortal:CPX-1134 (PMID:19188609) RGD PMID:19188609 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:28483668 RGD:12910717 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir140 microRNA 140 IMP RGD PMID:32519270 RGD:329347827 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO (PMID:23516523) RGD PMID:23516523 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 IMP RGD PMID:26888427 RGD:11040458 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5908331|PMID:22611253)		 UniProt
RGD		 PMID:22611253 GO_REF:0000024 MGI:5908331 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:24096089 RGD:10413842 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgr1 prostaglandin reductase 1 IDA RGD PMID:9667737 RGD:401959219 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO (MGI:5640904|PMID:25398325) RGD PMID:25398325 MGI:5640904 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:23422569 RGD:9585767 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
negative regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q61221 (MGI:3796473|PMID:18281291)		 Ensembl
RGD		 PMID:18281291 GO_REF:0000107 MGI:3796473 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IEA		 UniProtKB:Q61221 (MGI:3796473|PMID:18281291)
GO_REF:0000107		 RGD
Ensembl		 PMID:18281291 GO_REF:0000107 MGI:3796473 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:2154396 (PMID:7889565) RGD PMID:7889565 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Becn1 beclin 1 involved_in ISO UniProtKB:Q61221 (MGI:3796473|PMID:18281291) RGD PMID:18281291 MGI:3796473 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 involved_in ISO (MGI:5315337|PMID:21052097) RGD PMID:21052097 MGI:5315337 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO UniProtKB:Q61221 (MGI:3796473|PMID:18281291) RGD PMID:18281291 MGI:3796473 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA		 (PMID:23415688)
GO_REF:0000107		 RGD
Ensembl		 PMID:23415688 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Cryab crystallin, alpha B IDA RGD PMID:15358243 RGD:1598485 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:23608653 RGD:7364951 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in IEA
ISO		 GO_REF:0000107
(MGI:3796473|PMID:18281291)		 Ensembl
RGD		 PMID:18281291 GO_REF:0000107 MGI:3796473 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk2 hexokinase 2 involved_in ISO (MGI:5619449|PMID:22517678) RGD PMID:22517678 MGI:5619449 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (MGI:5315337|PMID:21052097) RGD PMID:21052097 MGI:5315337 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Mmp3 matrix metallopeptidase 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20969476)		 Ensembl
RGD		 PMID:20969476 GO_REF:0000107 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor involved_in ISO
IEA		 (MGI:5050076|PMID:17357786)
GO_REF:0000107		 RGD
Ensembl		 PMID:17357786 GO_REF:0000107 MGI:5050076 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17357786)		 UniProt
RGD		 PMID:17357786 GO_REF:0000024 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:18560593) RGD PMID:18560593 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5440401|PMID:22532565)		 UniProt
RGD		 PMID:22532565 GO_REF:0000024 MGI:5440401 NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS		 UniProtKB:Q9H4P4 (PMID:18541373)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:18541373 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5572869|PMID:17521387)		 UniProt
Ensembl
RGD		 PMID:17521387 GO_REF:0000024 GO_REF:0000107 MGI:5572869 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt3 sirtuin 3 IMP RGD PMID:23397292 RGD:9586042 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Sirt5 sirtuin 5 involved_in ISO (PMID:24140062) RGD PMID:24140062 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:20066163)		 UniProt
RGD		 PMID:20066163 GO_REF:0000024 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO MGI:5319187 (PMID:22044588) RGD PMID:22044588 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857263 (PMID:22044588)		 Ensembl
RGD		 PMID:22044588 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO
IEA		 (MGI:5689082|PMID:25470454)
GO_REF:0000107		 RGD
Ensembl		 PMID:25470454 GO_REF:0000107 MGI:5689082 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
negative regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2180086 (PMID:11168643)		 Ensembl
RGD		 PMID:11168643 GO_REF:0000107 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IMP RGD PMID:24601882 RGD:39128160 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Crp C-reactive protein IDA RGD PMID:9767445 RGD:9586000 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Pon3 paraoxonase 3 involved_in ISO
IEA		 (MGI:5543365|PMID:22441669)
GO_REF:0000107		 RGD
Ensembl		 PMID:22441669 GO_REF:0000107 MGI:5543365 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa1 dual oxidase maturation factor 1 involved_in ISO (PMID:22814254) RGD PMID:22814254 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 involved_in ISO (PMID:16651268), (PMID:22814254) RGD PMID:16651268 PMID:22814254 NCBI chr 3:109,245,337...109,249,055
Ensembl chr 3:109,245,476...109,248,968 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:27997345 RGD:12910740 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Nox4 NADPH oxidase 4 IMP RGD PMID:27279484 RGD:151347625 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Sod2 superoxide dismutase 2 IMP RGD PMID:20529999 RGD:27095884 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:12,615,455...12,623,615
Ensembl chr10:12,615,190...12,623,615 		JBrowse link
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nnt nicotinamide nucleotide transhydrogenase IMP RGD PMID:24722990 RGD:13513981 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:23507046)
GO_REF:0000107		 RGD
Ensembl		 PMID:23507046 GO_REF:0000107 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
positive regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in ISO
IEA		 (PMID:26838550)
GO_REF:0000107		 RGD
Ensembl		 PMID:26838550 GO_REF:0000107 NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15450084 RGD:2313867 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Cd36 CD36 molecule involved_in ISO
IEA		 (MGI:4438693|PMID:20037584)
GO_REF:0000107		 RGD
Ensembl		 PMID:20037584 GO_REF:0000107 MGI:4438693 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2447864 (PMID:16522634)		 Ensembl
RGD		 PMID:16522634 GO_REF:0000107 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119 		JBrowse link
G Cyba cytochrome b-245 alpha chain involved_in ISO
IEA		 (PMID:22423966)
GO_REF:0000107		 RGD
Ensembl		 PMID:22423966 GO_REF:0000107 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Foxo3 forkhead box O3 IMP RGD PMID:24278276 RGD:10402204 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in IGI PMID:17308309 ARUK-UCL PMID:17308309 RGD:12910994 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Hdac4 histone deacetylase 4 IMP RGD PMID:24166750 RGD:9681442 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Il4 interleukin 4 IDA RGD PMID:24073824 RGD:10402792 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Lcn2 lipocalin 2 IDA RGD PMID:25557118 RGD:126790477 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:27997345 RGD:12910740 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir24-2 microRNA 24-2 involved_in ISO (PMID:21788589) RGD PMID:21788589 NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790 		JBrowse link
G Mir675 microRNA 675 acts_upstream_of ISO (PMID:31574452) RGD PMID:31574452 NCBI chr 1:197,732,275...197,732,358
Ensembl chr 1:197,732,275...197,732,358 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase IMP RGD PMID:21712532 RGD:9590189 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) RGD PMID:22555455 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5300086|PMID:22041900)
GO_REF:0000107		 RGD
Ensembl		 PMID:22041900 GO_REF:0000107 MGI:5300086 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family involved_in ISO (PMID:24404184) RGD PMID:24404184 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 acts_upstream_of_or_within ISO (MGI:6414721|PMID:28128227) RGD PMID:28128227 MGI:6414721 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISO
IEA		 (MGI:4438693|PMID:20037584)
GO_REF:0000107		 RGD
Ensembl		 PMID:20037584 GO_REF:0000107 MGI:4438693 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) RGD PMID:20037584 MGI:4438693 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
positive regulation of reactive oxygen species metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) RGD PMID:23609450 MGI:5490396 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:19885844 RGD:7244243 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Cd36 CD36 molecule involved_in ISO (MGI:4850200|PMID:20978343) RGD PMID:20978343 MGI:4850200 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:20160708) RGD PMID:20160708 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IMP RGD PMID:20439821 RGD:7829726 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Dhrs4 dehydrogenase/reductase 4 involved_in ISO (PMID:19442656) RGD PMID:19442656 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Duoxa1 dual oxidase maturation factor 1 acts_upstream_of_or_within ISO MGI:2139422 (PMID:20233719) RGD PMID:20233719 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A IMP RGD PMID:20930373 RGD:10395362 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA
ISO		 GO_REF:0000107
(PMID:17275676)		 Ensembl
RGD		 PMID:17275676 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:20160708)		 Ensembl
RGD		 PMID:20160708 GO_REF:0000107 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Lcn2 lipocalin 2 IMP RGD PMID:30574656 RGD:126781752 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lep leptin IDA RGD PMID:20738325 RGD:8693628 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (MGI:4850200|PMID:20978343) RGD PMID:20978343 MGI:4850200 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nox1 NADPH oxidase 1 IMP RGD PMID:16254042 RGD:1581408 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nox4 NADPH oxidase 4 IMP RGD PMID:15848200 RGD:2324674 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 IMP RGD PMID:23554738 RGD:11073697 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20969476)
GO_REF:0000107		 ParkinsonsUK-UCL
RGD
Ensembl		 PMID:20969476 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19019919)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19019919 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:5284758|PMID:19019919)		 UniProt
RGD		 PMID:19019919 GO_REF:0000024 MGI:5284758 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) RGD PMID:20165904 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Plau plasminogen activator, urokinase IDA RGD PMID:16456094 RGD:6484217 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15158121 RGD:1642626 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 involved_in
acts_upstream_of_or_within		 ISO (MGI:5315337|PMID:21052097)
(PMID:19498109)		 RGD PMID:19498109 PMID:21052097 MGI:5315337 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO (PMID:18541373) RGD PMID:18541373 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511 		JBrowse link
G Romo1 reactive oxygen species modulator 1 involved_in ISO (PMID:16842742) RGD PMID:16842742 NCBI chr 3:144,659,709...144,661,310
Ensembl chr 3:144,659,826...144,661,310 		JBrowse link
G Sirpa signal-regulatory protein alpha involved_in ISO (PMID:24511121) RGD PMID:24511121 NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:18757424), (PMID:24511121) RGD PMID:18757424 PMID:24511121 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA		 (PMID:20160708)
GO_REF:0000107		 RGD
Ensembl		 PMID:20160708 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tspo translocator protein involved_in IDA
ISO		 (MGI:5689082|PMID:25470454) RGD PMID:25470454 PMID:12437594 MGI:5689082, RGD:2317161 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Xdh xanthine dehydrogenase involved_in IEA
ISO		 GO_REF:0000107
(PMID:18386220)		 Ensembl
RGD		 PMID:18386220 GO_REF:0000107 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISO (PMID:22739135) RGD PMID:22739135 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
positive regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:21376054 RGD:5129173 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:21076237 RGD:5129195 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:O88536 (PMID:11316806) RGD PMID:11316806 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Cd177 CD177 molecule involved_in ISO UniProtKB:P05107|UniProtKB:P11215 (PMID:21193407) RGD PMID:21193407 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19358895) RGD PMID:19358895 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Crp C-reactive protein involved_in ISO (PMID:24141169) RGD PMID:24141169 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5586806|PMID:10725737)		 Ensembl
RGD		 PMID:10725737 GO_REF:0000107 MGI:5586806 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cyba cytochrome b-245 alpha chain IMP RGD PMID:15036821 RGD:8693734 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:22966991 RGD:7204494 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 IMP RGD PMID:26682942 RGD:329961560 NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
ISS		 (PMID:11714832)
GO_REF:0000024		 RGD
UniProt		 PMID:11714832 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in ISO UniProtKB:P05067-PRO_0000000092 (MGI:5905278|PMID:11316806) RGD PMID:11316806 MGI:5905278 NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:27912212 RGD:13507308 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009187|PMID:11408560)		 BHF-UCL
RGD		 PMID:11408560 GO_REF:0000024 MGI:5009187 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:24935944 RGD:14985214 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Il18 interleukin 18 IMP RGD PMID:19497959 RGD:4889403 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO UniProtKB:P05107|UniProtKB:Q8N6Q3 (PMID:21193407)
(MGI:3812233|PMID:18685038), (MGI:3814938|PMID:18981141)		 RGD PMID:18685038 PMID:18981141 PMID:21193407 MGI:3812233 MGI:3814938 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb2 integrin subunit beta 2 involved_in ISO UniProtKB:P11215|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Mapt microtubule-associated protein tau involved_in ISO (PMID:22920254) RGD PMID:22920254 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Nox1 NADPH oxidase 1 IMP RGD PMID:24294978 PMID:26682942 RGD:329955573, RGD:329961560 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 involved_in ISO (PMID:24141169) RGD PMID:24141169 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA
ISS		 (PMID:19801500)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19801500 GO_REF:0000024 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
IEA		 (PMID:18219391)
GO_REF:0000107		 RGD
Ensembl		 PMID:18219391 GO_REF:0000107 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:19358895)
GO_REF:0000107		 RGD
Ensembl		 PMID:19358895 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:22073128)
GO_REF:0000024		 RGD
UniProt		 PMID:22073128 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (MGI:3812233|PMID:18685038) RGD PMID:18685038 MGI:3812233 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insr insulin receptor IDA in cerebellar granule neurons RGD PMID:17919343 RGD:2290474 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Noxa1 NADPH oxidase activator 1 involved_in ISO (PMID:16636067) RGD PMID:16636067 NCBI chr 3:7,895,488...7,907,011
Ensembl chr 3:7,895,488...7,905,967 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (MGI:5558956|PMID:24553947) RGD PMID:24553947 MGI:5558956 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2668456 (PMID:17325201)		 Ensembl
RGD		 PMID:17325201 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
regulation of reactive oxygen species biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:26210919)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26210919 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5810834|PMID:27214549)		 Ensembl
RGD		 PMID:27214549 GO_REF:0000107 MGI:5810834 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Ccn6 cellular communication network factor 6 involved_in ISO (PMID:27252383) RGD PMID:27252383 NCBI chr20:42,569,309...42,585,126
Ensembl chr20:42,569,309...42,585,126 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 involved_in ISO (PMID:30478045)
(MGI:6843609|PMID:24415791)		 RGD PMID:24415791 PMID:30478045 MGI:6843609 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 IMP RGD PMID:27279484 RGD:151347625 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing involved_in ISO
IBA		 (PMID:28779020)
GO_REF:0000033
(MGI:6103777|PMID:28779020)		 RGD
GO_Central		 PMID:28779020 GO_REF:0000033 MGI:6103777 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868 		JBrowse link
G Slc25a33 solute carrier family 25 member 33 involved_in ISO (PMID:20453889) RGD PMID:20453889 NCBI chr 5:160,195,040...160,219,961
Ensembl chr 5:160,195,042...160,219,961 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:5641585|PMID:25637806) RGD PMID:25637806 MGI:5641585 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Ucp1 uncoupling protein 1 involved_in NAS
ISO		 PMID:20416274
(MGI:4837058|PMID:20416274)		 RGD PMID:20416274 PMID:20416274 MGI:4837058, RGD:11541111 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
regulation of removal of superoxide radicals term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO
IEA		 (MGI:4850200|PMID:20978343)
GO_REF:0000107		 RGD
Ensembl		 PMID:20978343 GO_REF:0000107 MGI:4850200 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Dhfr dihydrofolate reductase involved_in ISO (MGI:5645206|PMID:19666465) RGD PMID:19666465 MGI:5645206 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Fbln5 fibulin 5 involved_in ISO (MGI:3610795|PMID:15528465) RGD PMID:15528465 MGI:3610795 NCBI chr 6:120,899,219...120,977,829
Ensembl chr 6:120,899,224...120,977,755 		JBrowse link
G Gch1 GTP cyclohydrolase 1 involved_in ISO (PMID:19666465) RGD PMID:19666465 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO (MGI:4850200|PMID:20978343) RGD PMID:20978343 MGI:4850200 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
regulation of superoxide anion generation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syk spleen associated tyrosine kinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:4414596|PMID:19797524)		 UniProt
RGD		 PMID:19797524 GO_REF:0000024 MGI:4414596 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
regulation of superoxide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir27b microRNA 27b involved_in ISO UniProtKB:P29353-1 (PMID:24177325) RGD PMID:24177325 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Shc1 SHC adaptor protein 1 involved_in ISO RNAcentral:URS000059311D_9606 (PMID:24177325) RGD PMID:24177325 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      regulation of metabolic process 6817
        regulation of cellular metabolic process 6095
          regulation of reactive oxygen species metabolic process 175
            negative regulation of reactive oxygen species metabolic process + 60
            positive regulation of reactive oxygen species metabolic process + 86
            regulation of hydrogen peroxide metabolic process + 21
            regulation of reactive oxygen species biosynthetic process + 60
            regulation of superoxide metabolic process + 37
Path 2
Term Annotations click to browse term
  biological_process 20115
    biological regulation 13553
      regulation of biological process 13127
        regulation of metabolic process 6817
          regulation of cellular metabolic process 6095
            regulation of reactive oxygen species metabolic process 175
              negative regulation of reactive oxygen species metabolic process + 60
              positive regulation of reactive oxygen species metabolic process + 86
              regulation of hydrogen peroxide metabolic process + 21
              regulation of reactive oxygen species biosynthetic process + 60
              regulation of superoxide metabolic process + 37
paths to the root