CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: linolenic acid
Accession: CHEBI:25048
browse the term
Definition: A two-membered subclass of octadecatrienoic acid comprising the (9Z,12Z,15Z)- and (6Z,9Z,12Z)-isomers. Linolenic acids are nutrients essential to the formation of prostaglandins and are also used in making paints and synthetic resins.
Synonyms: related_synonym: C18:3; Linolensaeure; linolenic acids
cyclic_relationship: is_conjugate_acid_of CHEBI:133790
G
Abca1
ATP binding cassette subfamily A member 1
decreases expression
ISO
trilinolenin results in decreased expression of ABCA1 mRNA
CTD
PMID:18356535
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abcg5
ATP binding cassette subfamily G member 5
decreases expression
ISO
trilinolenin results in decreased expression of ABCG5 mRNA
CTD
PMID:18356535
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Abcg8
ATP binding cassette subfamily G member 8
decreases expression
ISO
trilinolenin results in decreased expression of ABCG8 mRNA
CTD
PMID:18356535
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
decreases expression
ISO
trilinolenin results in decreased expression of CYP27A1 mRNA
CTD
PMID:18356535
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
ISO
trilinolenin results in increased expression of HMGCR mRNA
CTD
PMID:18356535
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Mttp
microsomal triglyceride transfer protein
increases expression
ISO
trilinolenin results in increased expression of MTTP mRNA
CTD
PMID:18356535
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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Npc1l1
NPC1 like intracellular cholesterol transporter 1
decreases expression
ISO
trilinolenin results in decreased expression of NPC1L1 mRNA
CTD
PMID:18356535
NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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Scd
stearoyl-CoA desaturase
decreases expression
ISO
trilinolenin results in decreased expression of SCD1 mRNA
CTD
PMID:8729090
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Abcb11
ATP binding cassette subfamily B member 11
multiple interactions
ISO
alpha-Linolenic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA]
CTD
PMID:15307955
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Acaca
acetyl-CoA carboxylase alpha
decreases expression
EXP
alpha-Linolenic Acid results in decreased expression of ACACA mRNA
CTD
PMID:14563831
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
G
Acly
ATP citrate lyase
decreases expression
EXP
alpha-Linolenic Acid results in decreased expression of ACLY mRNA
CTD
PMID:14563831
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Bche
butyrylcholinesterase
increases expression increases secretion
ISO
alpha-Linolenic Acid results in increased expression of BCHE mRNA alpha-Linolenic Acid results in increased secretion of BCHE protein
CTD
PMID:27106529
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Cat
catalase
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in decreased activity of CAT protein]
CTD
PMID:22269903
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of CCL2 protein]]
CTD
PMID:29423081
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Cebpb
CCAAT/enhancer binding protein beta
decreases expression
EXP
alpha-Linolenic Acid results in decreased expression of CEBPB mRNA
CTD
PMID:14563831
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression
ISO
alpha-Linolenic Acid results in increased expression of CPT1A mRNA
CTD
PMID:15307955
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Cybb
cytochrome b-245 beta chain
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [[Cholesterol co-treated with Particulate Matter] results in increased expression of CYBB protein]
CTD
PMID:30672636
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity
ISO
alpha-Linolenic Acid results in decreased activity of CYP1A2 protein
CTD
PMID:16978661
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
multiple interactions
ISO
alpha-Linolenic Acid inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]
CTD
PMID:19667161
NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
multiple interactions decreases activity
ISO
CYP2C19 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] alpha-Linolenic Acid results in decreased activity of CYP2C19 protein
CTD
PMID:16978661
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases activity
ISO
alpha-Linolenic Acid results in decreased activity of CYP2E1 protein
CTD
PMID:16978661
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
decreases activity
ISO
alpha-Linolenic Acid results in decreased activity of CYP3A4 protein
CTD
PMID:16978661
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Dio1
iodothyronine deiodinase 1
decreases activity
ISO
alpha-Linolenic Acid results in decreased activity of DIO1 protein
CTD
PMID:30561685
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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Dio2
iodothyronine deiodinase 2
decreases activity
ISO
alpha-Linolenic Acid results in decreased activity of DIO2 protein
CTD
PMID:30561685
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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Dio3
iodothyronine deiodinase 3
decreases activity
ISO
alpha-Linolenic Acid results in decreased activity of DIO3 protein
CTD
PMID:30561685
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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Fads1
fatty acid desaturase 1
multiple interactions
ISO
[[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated; [[alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated; [alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA; [alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA; fulvestrant inhibits the reaction [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA]
CTD
PMID:19576517
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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Fasn
fatty acid synthase
decreases expression
EXP
alpha-Linolenic Acid results in decreased expression of FASN mRNA
CTD
PMID:14563831
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Gclc
glutamate-cysteine ligase, catalytic subunit
increases activity increases expression
ISO
alpha-Linolenic Acid results in increased activity of GCLC protein alpha-Linolenic Acid results in increased expression of GCLC mRNA
CTD
PMID:17092368
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in increased activity of GPT protein]
CTD
PMID:22269903
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Gsta1
glutathione S-transferase alpha 1
increases expression multiple interactions
ISO
alpha-Linolenic Acid results in increased expression of GSTA1 mRNA NFE2L2 protein promotes the reaction [alpha-Linolenic Acid results in increased expression of GSTA1 mRNA]
CTD
PMID:28555106
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO EXP
alpha-Linolenic Acid results in increased expression of HMOX1 mRNA alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [Cholesterol results in increased expression of HMOX1 mRNA]]
CTD
PMID:17092368 PMID:30672636
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Ifng
interferon gamma
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [[Cholesterol co-treated with Particulate Matter] results in increased expression of IFNG protein]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IFNG protein]]
CTD
PMID:29423081 PMID:30672636
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il1b
interleukin 1 beta
multiple interactions
ISO EXP
[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in increased expression of IL1B protein alpha-Linolenic Acid inhibits the reaction [[Cholesterol co-treated with Particulate Matter] results in increased expression of IL1B protein]
CTD
PMID:16305726 PMID:30672636
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il4
interleukin 4
multiple interactions
ISO
[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in decreased expression of IL4 protein
CTD
PMID:16305726
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6
interleukin 6
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 protein]; alpha-Linolenic Acid inhibits the reaction [Cholesterol promotes the reaction [Particulate Matter results in increased expression of IL6 protein]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of IL6 mRNA]]
CTD
PMID:29423081 PMID:30672636
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Kng1
kininogen 1
multiple interactions
ISO
alpha-Linolenic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA]
CTD
PMID:15307955
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO EXP
NFE2L2 protein promotes the reaction [alpha-Linolenic Acid results in increased expression of CYP2A6 mRNA]; NFE2L2 protein promotes the reaction [alpha-Linolenic Acid results in increased expression of CYP2A6 protein]; NFE2L2 protein promotes the reaction [alpha-Linolenic Acid results in increased expression of GSTA1 mRNA] alpha-Linolenic Acid inhibits the reaction [Cholesterol promotes the reaction [Particulate Matter results in increased expression of NFE2L2 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Cholesterol results in increased expression of NFE2L2 mRNA]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [Cholesterol results in increased expression of NFE2L2 mRNA]]
CTD
PMID:28555106 PMID:30672636
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nos2
nitric oxide synthase 2
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 mRNA]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of NOS2 protein]]
CTD
PMID:29423081
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [Cholesterol results in increased expression of NQO1 mRNA]]
CTD
PMID:30672636
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1h2
nuclear receptor subfamily 1, group H, member 2
multiple interactions
ISO
alpha-Linolenic Acid binds to and results in increased activity of NR1H2 protein
CTD
PMID:16731579
NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
G
Nr1h4
nuclear receptor subfamily 1, group H, member 4
multiple interactions affects binding
ISO
alpha-Linolenic Acid inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] alpha-Linolenic Acid binds to NR1H4 protein
CTD
PMID:15307955
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
G
Pck1
phosphoenolpyruvate carboxykinase 1
multiple interactions
ISO
[Glucose deficiency co-treated with alpha-Linolenic Acid] results in increased expression of PCK1 mRNA
CTD
PMID:8536680
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Plin2
perilipin 2
increases expression
EXP ISO
alpha-Linolenic Acid results in increased expression of PLIN2 mRNA; alpha-Linolenic Acid results in increased expression of PLIN2 protein
CTD
PMID:16489205
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Ppara
peroxisome proliferator activated receptor alpha
multiple interactions affects abundance increases expression
EXP ISO
alpha-Linolenic Acid binds to and results in increased activity of PPARA protein PPARA protein affects the abundance of alpha-Linolenic Acid alpha-Linolenic Acid results in increased expression of PPARA mRNA alpha-Linolenic Acid binds to and results in increased activity of PPARA protein; Calcitriol promotes the reaction [alpha-Linolenic Acid results in increased expression of PPARA mRNA] alpha-Linolenic Acid binds to and results in increased activity of PPARA protein; Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of alpha-Linolenic Acid]
CTD
PMID:10403814 PMID:16731579 PMID:18154422 PMID:19667161 PMID:23619606
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Ppard
peroxisome proliferator-activated receptor delta
increases expression multiple interactions
ISO EXP
alpha-Linolenic Acid results in increased expression of PPARD mRNA; Calcitriol results in increased expression of [alpha-Linolenic Acid results in increased expression of PPARD mRNA] alpha-Linolenic Acid binds to and results in increased activity of PPARB protein
CTD
PMID:16731579 PMID:19667161
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Pparg
peroxisome proliferator-activated receptor gamma
increases expression increases activity multiple interactions
ISO EXP
alpha-Linolenic Acid results in increased expression of PPARG mRNA alpha-Linolenic Acid results in increased activity of PPARG protein alpha-Linolenic Acid binds to and results in increased activity of PPARG protein
CTD
PMID:16731579 PMID:18154422 PMID:20696231
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression decreases expression
ISO EXP
alpha-Linolenic Acid results in increased expression of PTGS2 mRNA alpha-Linolenic Acid results in increased expression of PTGS2 protein alpha-Linolenic Acid results in decreased expression of PTGS2 mRNA
CTD
PMID:14563831 PMID:17092368 PMID:22476691
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Rxra
retinoid X receptor alpha
multiple interactions affects binding
ISO
alpha-Linolenic Acid binds to and results in increased activity of RXRA protein alpha-Linolenic Acid binds to RXRA protein
CTD
PMID:16258897 PMID:16731579
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
EXP
alpha-Linolenic Acid results in decreased expression of SREBF1 mRNA
CTD
PMID:14563831
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Tnf
tumor necrosis factor
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein]; alpha-Linolenic Acid inhibits the reaction [Cholesterol promotes the reaction [Particulate Matter results in increased expression of TNF protein]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TNF protein]]
CTD
PMID:29423081 PMID:30672636
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
EXP
[alpha-Linolenic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein
CTD
PMID:17038422
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Ucp2
uncoupling protein 2
increases expression
EXP
alpha-Linolenic Acid results in increased expression of UCP2 mRNA
CTD
PMID:11341955
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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Vcam1
vascular cell adhesion molecule 1
multiple interactions
EXP
alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 mRNA]; alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 mRNA]]; alpha-Linolenic Acid inhibits the reaction [Particulate Matter promotes the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein]]; Particulate Matter inhibits the reaction [alpha-Linolenic Acid inhibits the reaction [[Cholesterol, Dietary co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of VCAM1 protein]]
CTD
PMID:29423081
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vdr
vitamin D receptor
increases expression multiple interactions
ISO
alpha-Linolenic Acid results in increased expression of VDR mRNA [Calcitriol co-treated with alpha-Linolenic Acid] results in increased expression of VDR mRNA
CTD
PMID:19667161
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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Lipc
lipase C, hepatic type
multiple interactions
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linolenate
CTD
PMID:24777581
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipg
lipase G, endothelial type
multiple interactions increases abundance
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linolenate LIPG gene mutant form results in increased abundance of cholesteryl linolenate
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
G
Abcg8
ATP binding cassette subfamily G member 8
affects expression
EXP
Corn Oil affects the expression of ABCG8 mRNA
CTD
PMID:16360708
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
G
Acaca
acetyl-CoA carboxylase alpha
increases expression
EXP
Corn Oil results in increased expression of ACACA mRNA
CTD
PMID:1973097
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
G
Acly
ATP citrate lyase
affects expression
EXP
Corn Oil affects the expression of ACLY mRNA
CTD
PMID:16360708
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
G
Acot2
acyl-CoA thioesterase 2
affects expression
EXP
Corn Oil affects the expression of ACOT2 mRNA
CTD
PMID:16360708
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
EXP
Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein]
CTD
PMID:29165388
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
G
Akr1b7
aldo-keto reductase family 1, member B7
affects expression
EXP
Corn Oil affects the expression of AKR1B7 mRNA
CTD
PMID:16360708
NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
G
Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
EXP
Corn Oil affects the expression of ALDH1A1 mRNA
CTD
PMID:16360708
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
G
Angptl4
angiopoietin-like 4
affects expression
EXP
Corn Oil affects the expression of ANGPTL4 mRNA
CTD
PMID:16360708
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
G
Areg
amphiregulin
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA
CTD
PMID:32186404
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
G
Bad
BCL2-associated agonist of cell death
increases expression
EXP
Corn Oil results in increased expression of BAD mRNA
CTD
PMID:22760963
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
G
Bdkrb1
bradykinin receptor B1
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein]
CTD
PMID:29165388
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
G
Bhlhe40
basic helix-loop-helix family, member e40
affects expression
EXP
Corn Oil affects the expression of BHLHE40 mRNA
CTD
PMID:16360708
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
G
Bhmt
betaine-homocysteine S-methyltransferase
affects expression
EXP
Corn Oil affects the expression of BHMT mRNA
CTD
PMID:16360708
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
G
Birc3
baculoviral IAP repeat-containing 3
increases expression
ISO
Corn Oil results in increased expression of BIRC3 mRNA
CTD
PMID:33263755
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
G
Bmp1
bone morphogenetic protein 1
affects expression
EXP
Corn Oil affects the expression of BMP1 mRNA
CTD
PMID:16360708
NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
G
Bmp2
bone morphogenetic protein 2
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA
CTD
PMID:32186404
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
G
Cadm1
cell adhesion molecule 1
affects expression
EXP
Corn Oil affects the expression of CADM1 mRNA
CTD
PMID:16360708
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
G
Calca
calcitonin-related polypeptide alpha
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA
CTD
PMID:32186404
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
G
Car6
carbonic anhydrase 6
increases expression
ISO
Corn Oil results in increased expression of CAR6 mRNA
CTD
PMID:33263755
NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
G
Card9
caspase recruitment domain family, member 9
increases expression
ISO
Corn Oil results in increased expression of CARD9 mRNA
CTD
PMID:33263755
NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
G
Cat
catalase
multiple interactions decreases expression
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein Corn Oil results in decreased expression of CAT protein
CTD
PMID:36432690
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cav3
caveolin 3
decreases expression
ISO
Corn Oil results in decreased expression of CAV3 mRNA
CTD
PMID:33263755
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
G
Ccl3
C-C motif chemokine ligand 3
increases expression decreases expression
ISO EXP
Corn Oil results in increased expression of CCL3 mRNA Corn Oil results in decreased expression of CCL3 mRNA
CTD
PMID:22760963 PMID:23409006
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
G
Ccnd1
cyclin D1
affects expression
EXP
Corn Oil affects the expression of CCND1 mRNA
CTD
PMID:16360708
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Cd36
CD36 molecule
decreases expression
EXP
Corn Oil results in decreased expression of CD36 mRNA
CTD
PMID:22760963
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cdhr1
cadherin-related family member 1
increases expression
EXP
Corn Oil results in increased expression of CDHR1 mRNA
CTD
PMID:22760963
NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
affects expression increases expression
EXP
Corn Oil affects the expression of CDKN1A mRNA Corn Oil results in increased expression of CDKN1A mRNA
CTD
PMID:16360708 PMID:22760963
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Cenpt
centromere protein T
increases expression
EXP
Corn Oil results in increased expression of CENPT mRNA
CTD
PMID:22760963
NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
G
Cfb
complement factor B
increases expression
EXP
Corn Oil results in increased expression of CFB mRNA
CTD
PMID:22760963
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cldn1
claudin 1
decreases expression
ISO
Corn Oil results in decreased expression of CLDN1 mRNA
CTD
PMID:33263755
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
G
Cldn9
claudin 9
increases expression
ISO
Corn Oil results in increased expression of CLDN9 mRNA
CTD
PMID:33263755
NCBI chr10:12,714,137...12,715,568
G
Cox7a1
cytochrome c oxidase subunit 7A1
decreases expression
ISO
Corn Oil results in decreased expression of COX7A1 mRNA
CTD
PMID:23409006
NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
G
Cpt1a
carnitine palmitoyltransferase 1A
increases expression multiple interactions affects expression
EXP ISO
Corn Oil results in increased expression of CPT1A mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA Corn Oil affects the expression of CPT1A mRNA
CTD
PMID:16360708 PMID:22760963 PMID:36432690
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Cpt2
carnitine palmitoyltransferase 2
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA
CTD
PMID:36432690
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
G
Crot
carnitine O-octanoyltransferase
affects expression multiple interactions
EXP ISO
Corn Oil affects the expression of CROT mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA
CTD
PMID:16360708 PMID:36432690
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
G
Ctsg
cathepsin G
increases expression
EXP
Corn Oil results in increased expression of CTSG mRNA
CTD
PMID:22760963
NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
affects expression
EXP
Corn Oil affects the expression of CYP17A1 mRNA
CTD
PMID:16360708
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
affects expression
EXP
Corn Oil affects the expression of CYP7A1 mRNA
CTD
PMID:16360708
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Cyp8b1
cytochrome P450 family 8 subfamily B member 1
affects expression
EXP
Corn Oil affects the expression of CYP8B1 mRNA
CTD
PMID:16360708
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
G
Ephx2
epoxide hydrolase 2
affects expression
EXP
Corn Oil affects the expression of EPHX2 mRNA
CTD
PMID:16360708
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
G
Ets1
ETS proto-oncogene 1, transcription factor
decreases expression
EXP
Corn Oil results in decreased expression of ETS1 mRNA
CTD
PMID:22760963
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
G
Fabp1
fatty acid binding protein 1
multiple interactions
EXP
[Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA
CTD
PMID:15016835
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
G
Fabp2
fatty acid binding protein 2
affects expression
EXP
Corn Oil affects the expression of FABP2 mRNA
CTD
PMID:16360708
NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
G
Fabp7
fatty acid binding protein 7
affects expression
EXP
Corn Oil affects the expression of FABP7 mRNA
CTD
PMID:16360708
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
G
Fasn
fatty acid synthase
affects expression
EXP
Corn Oil affects the expression of FASN mRNA
CTD
PMID:16360708
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fcgrt
Fc gamma receptor and transporter
decreases expression
EXP
Corn Oil results in decreased expression of FCGRT mRNA
CTD
PMID:22760963
NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
G
Fgb
fibrinogen beta chain
affects expression
EXP
Corn Oil affects the expression of FGB mRNA
CTD
PMID:16360708
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
G
Fgf21
fibroblast growth factor 21
affects expression
EXP
Corn Oil affects the expression of FGF21 mRNA
CTD
PMID:16360708
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
G
Fst
follistatin
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA
CTD
PMID:32186404
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
G
G0s2
G0/G1switch 2
affects expression
EXP
Corn Oil affects the expression of G0S2 mRNA
CTD
PMID:16360708
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
affects expression
EXP
Corn Oil affects the expression of GADD45A mRNA
CTD
PMID:16360708
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gal
galanin and GMAP prepropeptide
increases expression
EXP
Corn Oil results in increased expression of GAL mRNA
CTD
PMID:22760963
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
G
Gck
glucokinase
affects expression
EXP
Corn Oil affects the expression of GCK mRNA
CTD
PMID:16360708
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Gjd2
gap junction protein, delta 2
increases expression
ISO
Corn Oil results in increased expression of GJD2 mRNA
CTD
PMID:33263755
NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061
G
Got1
glutamic-oxaloacetic transaminase 1
affects expression
EXP
Corn Oil affects the expression of GOT1 mRNA
CTD
PMID:16360708
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Got2
glutamic-oxaloacetic transaminase 2
decreases expression
EXP
Corn Oil results in decreased expression of GOT2 mRNA
CTD
PMID:34987138
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
G
Gpd2
glycerol-3-phosphate dehydrogenase 2
affects expression
EXP
Corn Oil affects the expression of GPD2 mRNA
CTD
PMID:16360708
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]
CTD
PMID:29479035
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
H2ac25
H2A clustered histone 25
affects expression
EXP
Corn Oil affects the expression of H2A mRNA
CTD
PMID:16360708
NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
G
Hal
histidine ammonia lyase
affects expression
EXP
Corn Oil affects the expression of HAL mRNA
CTD
PMID:16360708
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
G
Hamp
hepcidin antimicrobial peptide
affects expression
EXP
Corn Oil affects the expression of HAMP mRNA
CTD
PMID:16360708
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
affects expression
EXP
Corn Oil affects the expression of HMGCR mRNA
CTD
PMID:16360708
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hoxa11
homeobox A11
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA
CTD
PMID:32186404
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
G
Hp
haptoglobin
increases expression
EXP
Corn Oil results in increased expression of HP mRNA
CTD
PMID:22760963
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Corn Oil results in increased expression of HSP90AA1 mRNA
CTD
PMID:33263755
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Idi1
isopentenyl-diphosphate delta isomerase 1
affects expression
EXP
Corn Oil affects the expression of IDI1 mRNA
CTD
PMID:16360708
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
G
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
affects expression increases expression
EXP
Corn Oil affects the expression of IGF2BP2 mRNA Corn Oil results in increased expression of IGF2BP2 mRNA
CTD
PMID:22760963
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
G
Igfbp1
insulin-like growth factor binding protein 1
affects expression
EXP
Corn Oil affects the expression of IGFBP1 mRNA
CTD
PMID:16360708
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
G
Ihh
Indian hedgehog signaling molecule
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA
CTD
PMID:32186404
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
G
Il12b
interleukin 12B
increases secretion
EXP
Corn Oil results in increased secretion of IL12B protein
CTD
PMID:33263755
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
G
Il18
interleukin 18
increases expression
ISO
Corn Oil results in increased expression of IL18 mRNA
CTD
PMID:33263755
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il1a
interleukin 1 alpha
increases secretion
EXP
Corn Oil results in increased secretion of IL1A protein
CTD
PMID:33263755
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
increases secretion
EXP
Corn Oil results in increased secretion of IL1B protein
CTD
PMID:33263755
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il1rn
interleukin 1 receptor antagonist
increases expression
EXP
Corn Oil results in increased expression of IL1RN mRNA
CTD
PMID:22760963
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
G
Il4
interleukin 4
increases expression increases secretion decreases expression
ISO EXP
Corn Oil results in increased expression of IL4 mRNA Corn Oil results in increased secretion of IL4 protein Corn Oil results in decreased expression of IL4 mRNA
CTD
PMID:23409006 PMID:33263755
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6r
interleukin 6 receptor
increases expression
EXP
Corn Oil results in increased expression of IL6R mRNA
CTD
PMID:22760963
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
G
Il9
interleukin 9
increases secretion
EXP
Corn Oil results in increased secretion of IL9 protein
CTD
PMID:33263755
NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
G
Inhbe
inhibin subunit beta E
affects expression
EXP
Corn Oil affects the expression of INHBE mRNA
CTD
PMID:16360708
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
G
Ins1
insulin 1
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein]
CTD
PMID:29165388
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Irak1
interleukin-1 receptor-associated kinase 1
increases expression
ISO
Corn Oil results in increased expression of IRAK1 mRNA
CTD
PMID:33263755
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
G
Irf5
interferon regulatory factor 5
increases expression
ISO
Corn Oil results in increased expression of IRF5 mRNA
CTD
PMID:33263755
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
G
Irf7
interferon regulatory factor 7
increases expression
ISO
Corn Oil results in increased expression of IRF7 mRNA
CTD
PMID:33263755
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Corn Oil results in increased expression of JUN mRNA
CTD
PMID:33263755
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Klf2
KLF transcription factor 2
affects expression
EXP
Corn Oil affects the expression of KLF2 mRNA
CTD
PMID:16360708
NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
G
Lcat
lecithin cholesterol acyltransferase
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA
CTD
PMID:36432690
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
G
Lcn2
lipocalin 2
increases expression
EXP
Corn Oil results in increased expression of LCN2 mRNA
CTD
PMID:22760963
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
G
Lep
leptin
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein]
CTD
PMID:29165388
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lgals1
galectin 1
increases expression
EXP
Corn Oil results in increased expression of LGALS1 mRNA
CTD
PMID:22760963
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
G
Lox
lysyl oxidase
multiple interactions
ISO
Corn Oil results in increased activity of and results in increased cleavage of LOX protein
CTD
PMID:26240151
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Ly75
lymphocyte antigen 75
increases expression
EXP
Corn Oil results in increased expression of LY75 mRNA
CTD
PMID:22760963
NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
G
Map2k1
mitogen activated protein kinase kinase 1
increases expression
ISO
Corn Oil results in increased expression of MAP2K1 mRNA
CTD
PMID:33263755
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Map2k3
mitogen activated protein kinase kinase 3
increases expression
ISO
Corn Oil results in increased expression of MAP2K3 mRNA
CTD
PMID:33263755
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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Map2k6
mitogen-activated protein kinase kinase 6
affects expression
EXP
Corn Oil affects the expression of MAP2K6 mRNA
CTD
PMID:16360708
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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Map3k7
mitogen activated protein kinase kinase kinase 7
increases expression
ISO
Corn Oil results in increased expression of MAP3K7 mRNA
CTD
PMID:33263755
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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Mapk1
mitogen activated protein kinase 1
increases expression
ISO
Corn Oil results in increased expression of MAPK1 mRNA
CTD
PMID:33263755
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14
mitogen activated protein kinase 14
increases expression
ISO
Corn Oil results in increased expression of MAPK14 mRNA
CTD
PMID:33263755
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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Mapk3
mitogen activated protein kinase 3
increases expression
ISO
Corn Oil results in increased expression of MAPK3 mRNA
CTD
PMID:33263755
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mdm2
MDM2 proto-oncogene
decreases expression
EXP
Corn Oil results in decreased expression of MDM2 mRNA
CTD
PMID:22760963
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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Mgmt
O-6-methylguanine-DNA methyltransferase
increases expression
EXP
Corn Oil results in increased expression of MGMT mRNA
CTD
PMID:22760963
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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Mgst2
microsomal glutathione S-transferase 2
increases expression
EXP
Corn Oil results in increased expression of MGST2 mRNA
CTD
PMID:22760963
NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
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Mlycd
malonyl-CoA decarboxylase
decreases expression
EXP
Corn Oil results in decreased expression of MLYCD mRNA
CTD
PMID:22760963
NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
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Msmo1
methylsterol monooxygenase 1
affects expression
EXP
Corn Oil affects the expression of MSMO1 mRNA
CTD
PMID:16360708
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA
CTD
PMID:36432690
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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Mx2
MX dynamin like GTPase 2
affects expression
EXP
Corn Oil affects the expression of MX2 mRNA
CTD
PMID:16360708
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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Myd88
MYD88, innate immune signal transduction adaptor
increases expression
ISO
Corn Oil results in increased expression of MYD88 mRNA
CTD
PMID:33263755
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Nfe2l2
NFE2 like bZIP transcription factor 2
decreases activity
ISO
Corn Oil results in decreased activity of NFE2L2 protein
CTD
PMID:30203046
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkbia
NFKB inhibitor alpha
increases expression
ISO
Corn Oil results in increased expression of NFKBIA mRNA
CTD
PMID:33263755
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nlrc4
NLR family, CARD domain containing 4
increases expression
ISO
Corn Oil results in increased expression of NLRC4 mRNA
CTD
PMID:33263755
NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
affects expression
EXP
Corn Oil affects the expression of NR1H4 mRNA
CTD
PMID:16360708
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
increases expression
EXP
Corn Oil results in increased expression of NR4A2 mRNA
CTD
PMID:22760963
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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Nsmce3
NSE3 homolog, SMC5-SMC6 complex component
affects expression
EXP
Corn Oil affects the expression of NSMCE3 mRNA
CTD
PMID:16360708
NCBI chr 1:118,401,302...118,402,629
G
Oat
ornithine aminotransferase
affects expression
EXP
Corn Oil affects the expression of OAT mRNA
CTD
PMID:16360708
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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Osgin1
oxidative stress induced growth inhibitor 1
affects expression
EXP
Corn Oil affects the expression of OSGIN1 mRNA
CTD
PMID:16360708
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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P2rx5
purinergic receptor P2X 5
affects expression
EXP
Corn Oil affects the expression of P2RX5 mRNA
CTD
PMID:16360708
NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
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Pax8
paired box 8
affects expression
EXP
Corn Oil affects the expression of PAX8 mRNA
CTD
PMID:16360708
NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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Pdgfa
platelet derived growth factor subunit A
affects expression
EXP
Corn Oil affects the expression of PDGFA mRNA
CTD
PMID:16360708
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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Pdgfrb
platelet derived growth factor receptor beta
increases expression
EXP
Corn Oil results in increased expression of PDGFRB mRNA
CTD
PMID:22760963
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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Pdlim1
PDZ and LIM domain 1
affects expression
EXP
Corn Oil affects the expression of PDLIM1 mRNA
CTD
PMID:16360708
NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
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Pdlim2
PDZ and LIM domain 2
affects expression
EXP
Corn Oil affects the expression of PDLIM2 mRNA
CTD
PMID:16360708
NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
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Pgf
placental growth factor
increases expression
EXP
Corn Oil results in increased expression of PGF mRNA
CTD
PMID:22760963
NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
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Pgrmc2
progesterone receptor membrane component 2
affects expression
EXP
Corn Oil affects the expression of PGRMC2 mRNA
CTD
PMID:16360708
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
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Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
increases expression
ISO
Corn Oil results in increased expression of PIK3CA mRNA
CTD
PMID:33263755
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
G
Plin2
perilipin 2
affects expression
EXP
Corn Oil affects the expression of PLIN2 mRNA
CTD
PMID:16360708
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Prlr
prolactin receptor
affects expression
EXP
Corn Oil affects the expression of PRLR mRNA
CTD
PMID:16360708
NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
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Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA
CTD
PMID:32186404
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Corn Oil affects the expression of PTPRF mRNA
CTD
PMID:16360708
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
G
Pycard
PYD and CARD domain containing
increases expression
ISO
Corn Oil results in increased expression of PYCARD mRNA
CTD
PMID:33263755
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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Rac1
Rac family small GTPase 1
increases expression
ISO
Corn Oil results in increased expression of RAC1 mRNA
CTD
PMID:33263755
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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Ripk1
receptor interacting serine/threonine kinase 1
increases expression
ISO
Corn Oil results in increased expression of RIPK1 mRNA
CTD
PMID:33263755
NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
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Ripk2
receptor-interacting serine-threonine kinase 2
increases expression
ISO
Corn Oil results in increased expression of RIPK2 mRNA
CTD
PMID:33263755
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
G
RT1-A
RT1 class I, locus A
increases expression
EXP
Corn Oil results in increased expression of RT1-A mRNA
CTD
PMID:22760963
G
RT1-Bb
RT1 class II, locus Bb
increases expression
EXP
Corn Oil results in increased expression of RT1-BB mRNA
CTD
PMID:22760963
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
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RT1-CE11
RT1 class I, locus CE11
decreases expression
EXP
Corn Oil results in decreased expression of RT1-CE11 mRNA
CTD
PMID:22760963
NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362
G
RT1-CE14
RT1 class I, locus CE14
increases expression
EXP
Corn Oil results in increased expression of RT1-CE14 mRNA
CTD
PMID:22760963
NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134
G
RT1-CE15
RT1 class I, locus CE15
decreases expression
EXP
Corn Oil results in decreased expression of RT1-CE15 mRNA
CTD
PMID:22760963
NCBI chr20:3,275,575...3,279,074
Ensembl chr20:3,264,172...3,279,563 Ensembl chr20:3,264,172...3,279,563
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RT1-CE16
RT1 class I, locus CE16
increases expression
EXP
Corn Oil results in increased expression of RT1-CE16 mRNA
CTD
PMID:22760963
NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
G
RT1-CE2
RT1 class I, locus CE2
increases expression
EXP
Corn Oil results in increased expression of RT1-CE2 mRNA
CTD
PMID:22760963
NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790
G
RT1-CE3
RT1 class I, locus CE3
increases expression
EXP
Corn Oil results in increased expression of RT1-CE3 mRNA
CTD
PMID:22760963
NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081
G
RT1-CE4
RT1 class I, locus CE4
increases expression
EXP
Corn Oil results in increased expression of RT1-CE4 mRNA
CTD
PMID:22760963
NCBI chr20:3,431,509...3,504,535
G
RT1-CE5
RT1 class I, locus CE5
increases expression
EXP
Corn Oil results in increased expression of RT1-CE5 mRNA
CTD
PMID:22760963
NCBI chr20:3,403,418...3,479,476
G
RT1-N1
RT1 class Ib, locus N1
decreases expression
EXP
Corn Oil results in decreased expression of RT1-N1 mRNA
CTD
PMID:22760963
G
S100a8
S100 calcium binding protein A8
increases expression
EXP
Corn Oil results in increased expression of S100A8 mRNA
CTD
PMID:22760963
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9
S100 calcium binding protein A9
increases expression
EXP
Corn Oil results in increased expression of S100A9 mRNA
CTD
PMID:22760963
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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Scd
stearoyl-CoA desaturase
affects expression
EXP
Corn Oil affects the expression of SCD1 mRNA
CTD
PMID:16360708
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scn1b
sodium voltage-gated channel beta subunit 1
affects expression
EXP
Corn Oil affects the expression of SCN1B mRNA
CTD
PMID:16360708
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
G
Sds
serine dehydratase
affects expression
EXP
Corn Oil affects the expression of SDS mRNA
CTD
PMID:16360708
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
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Sfrp2
secreted frizzled-related protein 2
decreases expression
EXP
Corn Oil results in decreased expression of SFRP2 mRNA
CTD
PMID:22760963
NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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Slc25a20
solute carrier family 25 member 20
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA
CTD
PMID:36432690
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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Slc25a25
solute carrier family 25 member 25
affects expression
EXP
Corn Oil affects the expression of SLC25A25 mRNA
CTD
PMID:16360708
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
G
Sod1
superoxide dismutase 1
decreases activity multiple interactions
ISO
Corn Oil results in decreased activity of SOD1 protein [Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]
CTD
PMID:17194920
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sparc
secreted protein acidic and cysteine rich
increases expression
EXP
Corn Oil results in increased expression of SPARC mRNA
CTD
PMID:22760963
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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Sqle
squalene epoxidase
affects expression
EXP
Corn Oil affects the expression of SQLE mRNA
CTD
PMID:16360708
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
G
Srebf1
sterol regulatory element binding transcription factor 1
affects expression
EXP
Corn Oil affects the expression of SREBF1 mRNA
CTD
PMID:16360708
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Sstr3
somatostatin receptor 3
decreases expression
EXP
Corn Oil results in decreased expression of SSTR3 mRNA
CTD
PMID:22760963
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
G
Sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
increases expression
ISO
Corn Oil results in increased expression of SUGT1 mRNA
CTD
PMID:33263755
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
G
Syk
spleen associated tyrosine kinase
increases expression
ISO
Corn Oil results in increased expression of SYK mRNA
CTD
PMID:23409006
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
G
Tac1
tachykinin, precursor 1
decreases expression
EXP
Corn Oil results in decreased expression of TAC1 mRNA
CTD
PMID:22760963
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
G
Tat
tyrosine aminotransferase
affects expression
EXP
Corn Oil affects the expression of TAT mRNA
CTD
PMID:16360708
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
G
Tbc1d14
TBC1 domain family, member 14
affects expression
EXP
Corn Oil affects the expression of TBC1D14 mRNA
CTD
PMID:16360708
NCBI chr14:74,172,652...74,272,182
Ensembl chr14:74,172,664...74,272,183
G
Tgfa
transforming growth factor alpha
decreases expression
EXP
Corn Oil results in decreased expression of TGFA mRNA
CTD
PMID:22760963
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
G
Ticam1
TIR domain containing adaptor molecule 1
increases expression
ISO
Corn Oil results in increased expression of TICAM1 mRNA
CTD
PMID:33263755
NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
G
Tjp2
tight junction protein 2
increases expression
ISO
Corn Oil results in increased expression of TJP2 mRNA
CTD
PMID:33263755
NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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Tjp3
tight junction protein 3
increases expression
ISO
Corn Oil results in increased expression of TJP3 mRNA
CTD
PMID:33263755
NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
G
Tnfrsf1a
TNF receptor superfamily member 1A
increases expression
ISO
Corn Oil results in increased expression of TNFRSF1A mRNA
CTD
PMID:33263755
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
G
Tollip
toll interacting protein
increases expression
ISO
Corn Oil results in increased expression of TOLLIP mRNA
CTD
PMID:33263755
NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625
G
Tpcn2
two pore segment channel 2
affects expression
EXP
Corn Oil affects the expression of TPCN2 mRNA
CTD
PMID:16360708
NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
G
Tpt1
tumor protein, translationally-controlled 1
increases expression
EXP
Corn Oil results in increased expression of TPT1 mRNA
CTD
PMID:22760963
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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Vegfb
vascular endothelial growth factor B
decreases expression
EXP
Corn Oil results in decreased expression of VEGFB mRNA
CTD
PMID:22760963
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
G
Vnn1
vanin 1
affects expression
EXP
Corn Oil affects the expression of VNN1 mRNA
CTD
PMID:16360708
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
G
Xiap
X-linked inhibitor of apoptosis
decreases expression
ISO
Corn Oil results in decreased expression of XIAP mRNA
CTD
PMID:33263755
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
G
Xpnpep2
X-prolyl aminopeptidase 2
affects expression
EXP
Corn Oil affects the expression of XPNPEP2 mRNA
CTD
PMID:16360708
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
G
Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Corn Oil affects the expression of ZDHHC23 mRNA
CTD
PMID:16360708
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
G
Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
gamma-Linolenic Acid results in increased expression of AKR1C1 mRNA
CTD
PMID:20664735
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
G
Apoh
apolipoprotein H
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of APOH mRNA
CTD
PMID:20664735
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
G
Ar
androgen receptor
multiple interactions
ISO
gamma-Linolenic Acid inhibits the reaction [Metribolone results in increased activity of AR protein]
CTD
PMID:18324785
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Asah1
N-acylsphingosine amidohydrolase 1
increases expression
ISO
gamma-Linolenic Acid results in increased expression of ASAH1 mRNA
CTD
PMID:20664735
NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
G
Casp3
caspase 3
increases activity
ISO
gamma-Linolenic Acid results in increased activity of CASP3 protein
CTD
PMID:16857180
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Ccna2
cyclin A2
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of CCNA2 protein
CTD
PMID:15318936
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
G
Ccne1
cyclin E1
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of CCNE1 protein
CTD
PMID:15318936
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
G
Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of CDK1 protein
CTD
PMID:15318936
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cldn5
claudin 5
multiple interactions
ISO
[gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of CLDN5 protein; [gamma-Linolenic Acid co-treated with Iodine] results in increased expression of and results in increased localization of CLDN5 protein; [Selenium co-treated with gamma-Linolenic Acid] results in increased expression of and results in increased localization of CLDN5 protein; gamma-Linolenic Acid results in increased expression of and results in increased localization of CLDN5 protein
CTD
PMID:16514648
NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992
G
Clta
clathrin, light chain A
increases expression
ISO
gamma-Linolenic Acid results in increased expression of CLTA mRNA
CTD
PMID:20664735
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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Fth1
ferritin heavy chain 1
increases expression
ISO
gamma-Linolenic Acid results in increased expression of FTH1 mRNA
CTD
PMID:20664735
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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Gclc
glutamate-cysteine ligase, catalytic subunit
increases activity increases expression
ISO
gamma-Linolenic Acid results in increased activity of GCLC protein gamma-Linolenic Acid results in increased expression of GCLC mRNA
CTD
PMID:17092368
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Grk5
G protein-coupled receptor kinase 5
increases expression
ISO
gamma-Linolenic Acid results in increased expression of GRK5 mRNA
CTD
PMID:20664735
NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
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Hexb
hexosaminidase subunit beta
increases expression
ISO
gamma-Linolenic Acid results in increased expression of HEXB mRNA
CTD
PMID:20664735
NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
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Hist1h2al1
histone cluster 1 H2A family like 1
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of H2AC6 mRNA
CTD
PMID:20664735
NCBI chr17:42,707,954...42,708,420
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Hmox1
heme oxygenase 1
increases expression
ISO
gamma-Linolenic Acid results in increased expression of HMOX1 mRNA; gamma-Linolenic Acid results in increased expression of HMOX1 protein
CTD
PMID:17092368 PMID:20664735
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Il2
interleukin 2
affects expression
ISO
gamma-Linolenic Acid affects the expression of IL2 protein
CTD
PMID:9415022
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Junb
JunB proto-oncogene, AP-1 transcription factor subunit
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of JUNB protein
CTD
PMID:15318936
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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Kynu
kynureninase
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of KYNU mRNA
CTD
PMID:20664735
NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
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Mapk3
mitogen activated protein kinase 3
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of MAPK3 protein
CTD
PMID:15318936
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mmp11
matrix metallopeptidase 11
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of MMP11 mRNA
CTD
PMID:20664735
NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of MYC protein
CTD
PMID:15318936
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Ocln
occludin
multiple interactions
ISO
[gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of OCLN protein; [gamma-Linolenic Acid co-treated with Iodine] results in increased expression of and results in increased localization of OCLN protein; [Selenium co-treated with gamma-Linolenic Acid] results in increased expression of and results in increased localization of OCLN protein; gamma-Linolenic Acid results in increased expression of and results in increased localization of OCLN protein
CTD
PMID:16514648
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
gamma-Linolenic Acid results in increased cleavage of PARP1 protein
CTD
PMID:10403056
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pcna
proliferating cell nuclear antigen
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of PCNA mRNA
CTD
PMID:20664735
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pdlim1
PDZ and LIM domain 1
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of PDLIM1 mRNA
CTD
PMID:20664735
NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
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Plin2
perilipin 2
increases expression
ISO
gamma-Linolenic Acid results in increased expression of PLIN2 mRNA
CTD
PMID:20664735
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
ISO
gamma-Linolenic Acid binds to and results in increased activity of PPARA protein
CTD
PMID:10403814
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
gamma-Linolenic Acid binds to and results in increased activity of PPARG protein
CTD
PMID:15318936
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ptgr1
prostaglandin reductase 1
increases expression
ISO
gamma-Linolenic Acid results in increased expression of PTGR1 mRNA
CTD
PMID:20664735
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
gamma-Linolenic Acid results in increased expression of PTGS2 mRNA
CTD
PMID:17092368
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Skp2
S-phase kinase associated protein 2
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of SKP2 mRNA
CTD
PMID:20664735
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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Slc3a2
solute carrier family 3 member 2
increases expression
ISO
gamma-Linolenic Acid results in increased expression of SLC3A2 mRNA
CTD
PMID:20664735
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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St13
ST13, Hsp70 interacting protein
increases expression
ISO
gamma-Linolenic Acid results in increased expression of ST13 mRNA
CTD
PMID:20664735
NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945
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Tff3
trefoil factor 3
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of TFF3 mRNA
CTD
PMID:20664735
NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
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Tjp1
tight junction protein 1
multiple interactions
ISO
[gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of TJP1 protein
CTD
PMID:16514648
NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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Tnf
tumor necrosis factor
decreases expression
ISO
gamma-Linolenic Acid results in decreased expression of TNF protein
CTD
PMID:9415022
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
EXP
gamma-Linolenic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]
CTD
PMID:17038422
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Txn1
thioredoxin 1
increases expression
ISO
gamma-Linolenic Acid results in increased expression of TXN mRNA
CTD
PMID:20664735
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
gamma-Linolenic Acid results in increased expression of TXNRD1 mRNA
CTD
PMID:20664735
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Abcb11
ATP binding cassette subfamily B member 11
affects expression
EXP
Soybean Oil affects the expression of ABCB11 mRNA
CTD
PMID:15770074
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1b
ATP-binding cassette, sub-family B member 1B
affects expression
EXP
Soybean Oil affects the expression of ABCB1B mRNA
CTD
PMID:15770074
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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Abcb4
ATP binding cassette subfamily B member 4
affects expression
EXP
Soybean Oil affects the expression of ABCB4 mRNA
CTD
PMID:15770074
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Abcc1
ATP binding cassette subfamily C member 1
affects expression
EXP
Soybean Oil affects the expression of ABCC1 mRNA
CTD
PMID:15770074
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc2
ATP binding cassette subfamily C member 2
affects expression
EXP
Soybean Oil affects the expression of ABCC2 mRNA
CTD
PMID:15770074
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc5
ATP binding cassette subfamily C member 5
affects expression
EXP
Soybean Oil affects the expression of ABCC5 mRNA
CTD
PMID:15770074
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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Abcc6
ATP binding cassette subfamily C member 6
affects expression
EXP
Soybean Oil affects the expression of ABCC6 mRNA
CTD
PMID:15770074
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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Acat1
acetyl-CoA acetyltransferase 1
decreases activity
EXP
Soybean Oil results in decreased activity of ACAT1 protein
CTD
PMID:12559476
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
G
Bcl2
BCL2, apoptosis regulator
increases expression
EXP
Soybean Oil results in increased expression of BCL2 protein
CTD
PMID:15309441
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Cat
catalase
increases activity
EXP
Soybean Oil results in increased activity of CAT protein
CTD
PMID:12781854
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccnd1
cyclin D1
increases expression
EXP
Soybean Oil results in increased expression of CCND1 mRNA
CTD
PMID:21088903
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Cyp4a1
cytochrome P450, family 4, subfamily a, polypeptide 1
affects expression
EXP
Soybean Oil affects the expression of CYP4A1 mRNA
CTD
PMID:16079505
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases activity
EXP
Soybean Oil results in increased activity of CYP7A1 protein
CTD
PMID:12559476
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Gstp1
glutathione S-transferase pi 1
multiple interactions
EXP
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]
CTD
PMID:11600134
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases activity
EXP
Soybean Oil results in increased activity of HMGCR protein
CTD
PMID:12559476
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Il12b
interleukin 12B
decreases expression
ISO
Soybean Oil results in decreased expression of IL12B mRNA
CTD
PMID:10065739
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Soybean Oil affects the expression of SLC22A1 mRNA
CTD
PMID:15770074
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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Slc22a7
solute carrier family 22 member 7
affects expression
EXP
Soybean Oil affects the expression of SLC22A7 mRNA
CTD
PMID:15770074
NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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