|
Symbol |
Object Name |
Qualifiers
|
Evidence |
Notes |
Source |
PubMed Reference(s) |
RGD Reference(s) |
Position |
|
G
|
Aars2
|
alanyl-tRNA synthetase 2, mitochondrial
|
increases expression
|
ISO
|
butylparaben results in increased expression of AARS2 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 9:22,981,880...22,993,536
Ensembl chr 9:15,297,531...15,496,090
|
|
G
|
Abat
|
4-aminobutyrate aminotransferase
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of ABAT mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
|
|
G
|
Acan
|
aggrecan
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of ACAN mRNA
|
CTD |
PMID:28527915 |
|
NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
|
|
G
|
Acsl6
|
acyl-CoA synthetase long-chain family member 6
|
increases expression
|
ISO
|
butylparaben results in increased expression of ACSL6 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr10:38,940,668...38,999,515
Ensembl chr10:38,440,080...38,498,757
|
|
G
|
Actn1
|
actinin, alpha 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ACTN1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
|
|
G
|
Adam17
|
ADAM metallopeptidase domain 17
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ADAM17 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of ADAM17 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639
|
|
G
|
Adipoq
|
adiponectin, C1Q and collagen domain containing
|
multiple interactions increases expression
|
ISO
|
butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein] butylparaben results in increased expression of ADIPOQ mRNA 2-chloro-5-nitrobenzanilide inhibits the reaction [butylparaben results in increased expression of ADIPOQ mRNA]; bisphenol A diglycidyl ether inhibits the reaction [butylparaben results in increased expression of ADIPOQ mRNA]; butylparaben promotes the reaction [Dexamethasone results in increased expression of ADIPOQ mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of ADIPOQ mRNA]
|
CTD |
PMID:22956630 PMID:31016361 |
|
NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564
|
|
G
|
Adm
|
adrenomedullin
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of ADM mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654
|
|
G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
decreases expression multiple interactions
|
ISO
|
butylparaben results in decreased expression of ALPL mRNA NR3C1 protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA]; PPARG protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA]
|
CTD |
PMID:28527915 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:149,951,409...150,006,446
|
|
G
|
Amh
|
anti-Mullerian hormone
|
increases expression
|
EXP
|
butylparaben results in increased expression of AMH mRNA
|
CTD |
PMID:22777679 PMID:28208728 |
|
NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282
|
|
G
|
Ar
|
androgen receptor
|
affects binding decreases expression affects expression
|
EXP
|
butylparaben binds to AR protein butylparaben results in decreased expression of AR mRNA; butylparaben results in decreased expression of AR protein butylparaben affects the expression of AR protein
|
CTD |
PMID:20371976 PMID:26888303 PMID:27444704 |
|
NCBI chr X:67,135,317...67,304,476
Ensembl chr X:63,104,771...63,273,925
|
|
G
|
Arhgap9
|
Rho GTPase activating protein 9
|
increases expression
|
ISO
|
butylparaben results in increased expression of ARHGAP9 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
|
|
G
|
Atf4
|
activating transcription factor 4
|
increases expression
|
ISO
|
butylparaben results in increased expression of ATF4 mRNA
|
CTD |
PMID:36277366 |
|
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446
|
|
G
|
Atf6
|
activating transcription factor 6
|
increases expression
|
ISO
|
butylparaben results in increased expression of ATF6 protein
|
CTD |
PMID:29319206 |
|
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
|
|
G
|
Atm
|
ATM serine/threonine kinase
|
affects expression
|
ISO
|
butylparaben affects the expression of ATM mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437
|
|
G
|
Atp5mg
|
ATP synthase membrane subunit G
|
increases expression
|
ISO
|
butylparaben results in increased expression of ATP5MG mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 8:54,122,457...54,130,407
Ensembl chr 8:45,225,686...45,233,559
|
|
G
|
Atr
|
ATR serine/threonine kinase
|
increases expression
|
ISO
|
butylparaben results in increased expression of ATR mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:96,426,724...96,524,136
|
|
G
|
Avp
|
arginine vasopressin
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of AVP mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425
|
|
G
|
Bcl2l1
|
Bcl2-like 1
|
increases expression
|
ISO
|
butylparaben results in increased expression of BCL2L1 mRNA; butylparaben results in increased expression of BCL2L1 protein
|
CTD |
PMID:24481588 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
|
|
G
|
Bdnf
|
brain-derived neurotrophic factor
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of BDNF mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615
|
|
G
|
Bglap
|
bone gamma-carboxyglutamate protein
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of BGLAP mRNA
|
CTD |
PMID:28527915 |
|
NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495
|
|
G
|
Bsn
|
bassoon (presynaptic cytomatrix protein)
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of BSN mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819
|
|
G
|
Cacna1a
|
calcium voltage-gated channel subunit alpha1 A
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1A mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr19:40,425,560...40,724,810
Ensembl chr19:23,520,741...23,823,225
|
|
G
|
Cacna1c
|
calcium voltage-gated channel subunit alpha1 C
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] affects the expression of CACNA1C mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1C mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648
|
|
G
|
Cacna1d
|
calcium voltage-gated channel subunit alpha1 D
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1D mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215
|
|
G
|
Cacna1e
|
calcium voltage-gated channel subunit alpha1 E
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1E mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr13:69,125,048...69,613,795
Ensembl chr13:66,581,920...66,894,450
|
|
G
|
Cacna1f
|
calcium voltage-gated channel subunit alpha1 F
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1F mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr X:17,539,992...17,568,308
Ensembl chr X:14,868,024...14,896,413
|
|
G
|
Cacna1g
|
calcium voltage-gated channel subunit alpha1 G
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNA1G mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1G mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,355,008...79,422,752
|
|
G
|
Cacna1h
|
calcium voltage-gated channel subunit alpha1 H
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA1H mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,390,113...14,448,376
|
|
G
|
Cacna1i
|
calcium voltage-gated channel subunit alpha1 I
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNA1I mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:113,716,266...113,827,670
Ensembl chr 7:111,836,012...111,944,688
|
|
G
|
Cacna2d1
|
calcium voltage-gated channel auxiliary subunit alpha2delta 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA2D1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNA2D1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:18,951,002...19,374,969
|
|
G
|
Cacna2d2
|
calcium voltage-gated channel auxiliary subunit alpha2delta 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA2D2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA2D2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:108,072,454...108,203,173
|
|
G
|
Cacna2d3
|
calcium voltage-gated channel auxiliary subunit alpha2delta 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] affects the expression of CACNA2D3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA2D3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr16:4,105,048...4,919,037
Ensembl chr16:4,098,445...4,912,351
|
|
G
|
Cacnb1
|
calcium voltage-gated channel auxiliary subunit beta 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNB1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:83,494,509...83,515,164
Ensembl chr10:82,998,182...83,018,694
|
|
G
|
Cacnb2
|
calcium voltage-gated channel auxiliary subunit beta 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNB2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNB2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr17:82,473,097...82,818,564
Ensembl chr17:77,564,460...77,909,106
|
|
G
|
Cacnb3
|
calcium voltage-gated channel auxiliary subunit beta 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNB3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNB3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:129,783,674...129,797,074
|
|
G
|
Cacng2
|
calcium voltage-gated channel auxiliary subunit gamma 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNG2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:109,574,459...109,697,227
|
|
G
|
Cacng5
|
calcium voltage-gated channel auxiliary subunit gamma 5
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG5 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:93,327,142...93,369,244
Ensembl chr10:92,829,196...92,869,614
|
|
G
|
Cacng6
|
calcium voltage-gated channel auxiliary subunit gamma 6
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNG6 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG6 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:74,648,342...74,663,351
Ensembl chr 1:65,732,632...65,747,341
|
|
G
|
Cacng8
|
calcium voltage-gated channel auxiliary subunit gamma 8
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CACNG8 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:74,670,767...74,691,003
Ensembl chr 1:65,755,334...65,779,089
|
|
G
|
Calb2
|
calbindin 2
|
increases expression
|
ISO
|
butylparaben results in increased expression of CALB2 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
|
|
G
|
Camk2b
|
calcium/calmodulin-dependent protein kinase II beta
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CAMK2B mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994
|
|
G
|
Cartpt
|
CART prepropeptide
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in increased expression of CARTPT mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
|
|
G
|
Cask
|
calcium/calmodulin dependent serine protein kinase
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CASK mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CASK mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr X:11,572,328...11,915,831
Ensembl chr X:8,899,833...9,238,694
|
|
G
|
Casp8
|
caspase 8
|
increases expression
|
ISO
|
butylparaben results in increased expression of CASP8 protein
|
CTD |
PMID:24481588 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
|
|
G
|
Cat
|
catalase
|
decreases activity multiple interactions
|
EXP
|
butylparaben results in decreased activity of CAT protein butylparaben inhibits the reaction [Triclosan results in increased activity of CAT protein]
|
CTD |
PMID:29350491 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Ccna1
|
cyclin A1
|
increases expression
|
ISO
|
butylparaben results in increased expression of CCNA1 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
|
|
G
|
Ccna2
|
cyclin A2
|
increases expression
|
ISO
|
butylparaben results in increased expression of CCNA2 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577
|
|
G
|
Ccnb2
|
cyclin B2
|
increases expression
|
ISO
|
butylparaben results in increased expression of CCNB2 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
|
|
G
|
Ccnd1
|
cyclin D1
|
increases expression
|
ISO
|
butylparaben results in increased expression of CCND1 mRNA
|
CTD |
PMID:23524099 PMID:24481588 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
|
|
G
|
Ccnd3
|
cyclin D3
|
affects expression decreases expression
|
ISO
|
butylparaben affects the expression of CCND3 mRNA butylparaben results in decreased expression of CCND3 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:13,394,169...13,489,371
|
|
G
|
Ccne1
|
cyclin E1
|
affects expression
|
ISO
|
butylparaben affects the expression of CCNE1 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101
|
|
G
|
Ccne2
|
cyclin E2
|
increases expression
|
ISO
|
butylparaben results in increased expression of CCNE2 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632
|
|
G
|
Cd44
|
CD44 molecule
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CD44 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CD44 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620
|
|
G
|
Cdc25a
|
cell division cycle 25A
|
increases expression
|
ISO
|
butylparaben results in increased expression of CDC25A mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:109,864,478...109,882,701
|
|
G
|
Cdk2
|
cyclin dependent kinase 2
|
increases expression
|
ISO
|
butylparaben results in increased expression of CDK2 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403
|
|
G
|
Cdk4
|
cyclin-dependent kinase 4
|
increases expression
|
ISO
|
butylparaben results in increased expression of CDK4 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403
|
|
G
|
Cdk6
|
cyclin-dependent kinase 6
|
affects expression
|
ISO
|
butylparaben affects the expression of CDK6 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634
|
|
G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of CDKN1A mRNA; butylparaben results in decreased expression of CDKN1A protein
|
CTD |
PMID:24481588 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
|
|
G
|
Cebpa
|
CCAAT/enhancer binding protein alpha
|
multiple interactions increases expression
|
ISO
|
2-chloro-5-nitrobenzanilide inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]; bisphenol A diglycidyl ether inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]; butylparaben promotes the reaction [Dexamethasone results in increased expression of CEBPA mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of CEBPA mRNA]; Rimonabant inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]
|
CTD |
PMID:22956630 PMID:27659731 PMID:28527915 |
|
NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412
|
|
G
|
Celf5
|
CUGBP, Elav-like family member 5
|
increases expression
|
ISO
|
butylparaben results in increased expression of CELF5 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 7:8,225,787...8,250,322
Ensembl chr 7:8,225,825...8,250,322
|
|
G
|
Chrdl1
|
chordin-like 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CHRDL1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr X:106,889,125...106,992,937
Ensembl chr X:106,889,125...106,992,921
|
|
G
|
Chst1
|
carbohydrate sulfotransferase 1
|
increases expression
|
ISO
|
butylparaben results in increased expression of CHST1 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883
|
|
G
|
Cntn3
|
contactin 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CNTN3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:134,841,268...135,214,460
Ensembl chr 4:134,842,266...135,125,613
|
|
G
|
Cntn4
|
contactin 4
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CNTN4 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:138,624,584...139,622,499
Ensembl chr 4:139,099,152...139,621,090
|
|
G
|
Col10a1
|
collagen type X alpha 1 chain
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of COL10A1 mRNA
|
CTD |
PMID:28527915 |
|
NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
|
|
G
|
Col2a1
|
collagen type II alpha 1 chain
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of COL2A1 mRNA
|
CTD |
PMID:28527915 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G
|
Col8a1
|
collagen type VIII alpha 1 chain
|
increases expression
|
ISO
|
butylparaben results in increased expression of COL8A1 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
|
|
G
|
Cops2
|
COP9 signalosome subunit 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of COPS2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 3:113,084,174...113,110,090
Ensembl chr 3:113,084,176...113,109,947
|
|
G
|
Crh
|
corticotropin releasing hormone
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919
|
|
G
|
Cyba
|
cytochrome b-245 alpha chain
|
increases expression
|
ISO
|
butylparaben results in increased expression of CYBA mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
|
|
G
|
Cycs
|
cytochrome c, somatic
|
increases expression
|
ISO
|
butylparaben results in increased expression of CYCS protein
|
CTD |
PMID:29319206 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
|
|
G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
decreases expression affects expression
|
EXP
|
butylparaben results in decreased expression of CYP11A1 mRNA; butylparaben results in decreased expression of CYP11A1 protein butylparaben affects the expression of CYP11A1 mRNA
|
CTD |
PMID:22777679 PMID:26888303 |
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338
|
|
G
|
Cyp11b2
|
cytochrome P450, family 11, subfamily b, polypeptide 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of CYP11B1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:106,838,590...106,845,004
|
|
G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP17A1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573
|
|
G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
decreases expression affects expression increases expression multiple interactions increases activity
|
EXP ISO
|
butylparaben results in decreased expression of CYP19A1 mRNA butylparaben affects the expression of CYP19A1 protein butylparaben results in increased expression of CYP19A1 mRNA [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CYP19A1 mRNA butylparaben results in increased activity of CYP19A1 protein butylparaben results in decreased expression of CYP19A1 mRNA; butylparaben results in decreased expression of CYP19A1 protein
|
CTD |
PMID:23744433 PMID:25607892 PMID:26888303 PMID:27122241 PMID:30817981 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758
|
|
G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions decreases activity
|
ISO EXP
|
[butylparaben co-treated with triclocarban] results in increased expression of CYP1A1 mRNA butylparaben results in decreased activity of CYP1A1 protein
|
CTD |
PMID:23524099 PMID:27432241 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
|
|
G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
decreases activity
|
EXP
|
butylparaben results in decreased activity of CYP1A2 protein
|
CTD |
PMID:27432241 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312
|
|
G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
increases expression multiple interactions
|
ISO
|
butylparaben results in increased expression of CYP1B1 mRNA butylparaben promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA]
|
CTD |
PMID:23524099 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
|
|
G
|
Cyp2b1
|
cytochrome P450, family 2, subfamily b, polypeptide 1
|
decreases activity
|
EXP
|
butylparaben results in decreased activity of CYP2B1 protein
|
CTD |
PMID:27432241 |
|
NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052
|
|
G
|
Cyp2c11
|
cytochrome P450, subfamily 2, polypeptide 11
|
decreases activity
|
EXP
|
butylparaben results in decreased activity of CYP2C11 protein
|
CTD |
PMID:27432241 |
|
NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:236,762,842...236,799,066
|
|
G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
decreases activity
|
EXP
|
butylparaben results in decreased activity of CYP2E1 protein
|
CTD |
PMID:27432241 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
|
|
G
|
Cyp3a62
|
cytochrome P450, family 3, subfamily a, polypeptide 62
|
decreases activity
|
EXP
|
butylparaben results in decreased activity of CYP3A62 protein
|
CTD |
PMID:27432241 |
|
NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
|
|
G
|
Dcc
|
DCC netrin 1 receptor
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of DCC mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr18:67,144,272...68,248,159
Ensembl chr18:64,873,898...65,972,740
|
|
G
|
Ddit3
|
DNA-damage inducible transcript 3
|
increases expression
|
ISO
|
butylparaben results in increased expression of DDIT3 protein butylparaben results in increased expression of DDIT3 mRNA
|
CTD |
PMID:29319206 PMID:36277366 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
|
|
G
|
Diablo
|
diablo, IAP-binding mitochondrial protein
|
increases expression
|
ISO
|
butylparaben results in increased expression of DIABLO mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
|
|
G
|
Dio1
|
iodothyronine deiodinase 1
|
affects expression decreases activity
|
EXP
|
butylparaben affects the expression of DIO1 mRNA butylparaben results in decreased activity of DIO1 protein
|
CTD |
PMID:32798586 |
|
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
|
|
G
|
Dlg1
|
discs large MAGUK scaffold protein 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of DLG1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689
|
|
G
|
Dlg4
|
discs large MAGUK scaffold protein 4
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of DLG4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of DLG4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of DLG4 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:55,239,397...55,267,780
Ensembl chr10:54,739,470...54,767,153
|
|
G
|
Dlgap3
|
DLG associated protein 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of DLGAP3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of DLGAP3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 5:139,491,972...139,562,625
Ensembl chr 5:139,492,947...139,562,625
|
|
G
|
Dnm1
|
dynamin 1
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of DNM1 mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr 3:36,002,535...36,055,220
Ensembl chr 3:15,604,784...15,648,538
|
|
G
|
Dnmt3a
|
DNA methyltransferase 3 alpha
|
multiple interactions increases expression
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of DNMT3A mRNA butylparaben results in increased expression of DNMT3A mRNA
|
CTD |
PMID:25607892 PMID:26888303 |
|
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687
|
|
G
|
Dnmt3b
|
DNA methyltransferase 3 beta
|
increases expression
|
EXP
|
butylparaben results in increased expression of DNMT3B mRNA
|
CTD |
PMID:26888303 |
|
NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:142,130,592...142,169,124
|
|
G
|
Dpp6
|
dipeptidyl peptidase like 6
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of DPP6 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532
|
|
G
|
E2f1
|
E2F transcription factor 1
|
affects expression
|
ISO
|
butylparaben affects the expression of E2F1 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361
|
|
G
|
E2f3
|
E2F transcription factor 3
|
affects expression
|
ISO
|
butylparaben affects the expression of E2F3 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
|
|
G
|
Efna4
|
ephrin A4
|
increases expression
|
ISO
|
butylparaben results in increased expression of EFNA4 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979
|
|
G
|
Egf
|
epidermal growth factor
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of EGF mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:218,219,415...218,302,064
|
|
G
|
Elp6
|
elongator acetyltransferase complex subunit 6
|
increases expression
|
ISO
|
butylparaben results in increased expression of ELP6 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 8:110,280,059...110,295,070
Ensembl chr 8:110,279,979...110,295,067
|
|
G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078
|
|
G
|
Erbb3
|
erb-b2 receptor tyrosine kinase 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of ERBB3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525
|
|
G
|
Erbb4
|
erb-b2 receptor tyrosine kinase 4
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ERBB4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of ERBB4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of ERBB4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of ERBB4 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
|
|
G
|
Ercc2
|
ERCC excision repair 2, TFIIH core complex helicase subunit
|
increases expression
|
ISO
|
butylparaben results in increased expression of ERCC2 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
|
|
G
|
Ern1
|
endoplasmic reticulum to nucleus signaling 1
|
increases expression
|
ISO
|
butylparaben results in increased expression of ERN1 protein
|
CTD |
PMID:29319206 |
|
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029
|
|
G
|
Esr1
|
estrogen receptor 1
|
affects binding decreases methylation multiple interactions increases expression decreases expression decreases activity increases activity
|
ISO EXP
|
butylparaben binds to ESR1 protein; butylparaben metabolite binds to ESR1 protein butylparaben results in decreased methylation of ESR1 promoter [butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer]; butylparaben binds to and results in increased activity of ESR1 protein; Fulvestrant inhibits the reaction [butylparaben results in increased activity of ESR1 protein] butylparaben results in increased expression of ESR1 mRNA; butylparaben results in increased expression of ESR1 protein butylparaben results in decreased expression of ESR1 mRNA butylparaben results in decreased activity of ESR1 protein [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA; butylparaben inhibits the reaction [Estradiol binds to ESR1 protein]; Fulvestrant inhibits the reaction [butylparaben results in decreased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [butylparaben results in decreased expression of ESR1 protein] butylparaben results in decreased expression of ESR1 mRNA; butylparaben results in decreased expression of ESR1 protein
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CTD |
PMID:11193391 PMID:15204698 PMID:19063592 PMID:19654335 PMID:20074635 PMID:20132880 PMID:20362049 PMID:20435135 PMID:22562034 PMID:23524099 PMID:23567241 PMID:25012808 PMID:25128701 PMID:26502914 PMID:26888303 PMID:27444704 PMID:29945225 PMID:34383603 More...
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NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
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G
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Esr2
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estrogen receptor 2
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affects binding increases expression decreases expression multiple interactions
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EXP ISO
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butylparaben binds to ESR2 protein butylparaben results in increased expression of ESR2 mRNA; butylparaben results in increased expression of ESR2 protein butylparaben results in decreased expression of ESR2 mRNA butylparaben binds to and results in increased activity of ESR2 protein
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CTD |
PMID:11193391 PMID:18648085 PMID:20132880 PMID:23567241 PMID:25128701 PMID:26888303 More...
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NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919
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G
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Esrrg
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estrogen-related receptor gamma
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multiple interactions
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ISO
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butylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]]
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CTD |
PMID:23583298 |
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NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
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G
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Faah
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fatty acid amide hydrolase
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decreases activity
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ISO EXP
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butylparaben results in decreased activity of FAAH protein
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CTD |
PMID:27659731 |
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NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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G
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Fabp4
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fatty acid binding protein 4
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multiple interactions increases expression
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ISO
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butylparaben promotes the reaction [Dexamethasone results in increased expression of FABP4 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA]
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CTD |
PMID:22956630 PMID:24155963 PMID:27659731 PMID:28527915 |
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NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578
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G
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Fasn
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fatty acid synthase
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increases expression multiple interactions
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ISO
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butylparaben results in increased expression of FASN mRNA butylparaben promotes the reaction [Dexamethasone results in increased expression of FASN mRNA]
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CTD |
PMID:22956630 |
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NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261
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G
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Fgfr1
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Fibroblast growth factor receptor 1
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of FGFR1 mRNA
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CTD |
PMID:25607892 |
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NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350
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G
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Fgfr2
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fibroblast growth factor receptor 2
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of FGFR2 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626
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G
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Foxl2
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forkhead box L2
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increases expression
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EXP
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butylparaben results in increased expression of FOXL2 mRNA
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CTD |
PMID:22777679 |
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NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427
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G
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Fshb
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follicle stimulating hormone subunit beta
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decreases secretion decreases expression increases secretion
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EXP
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butylparaben results in decreased secretion of FSHB protein butylparaben results in decreased expression of FSHB protein butylparaben results in increased secretion of FSHB protein
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CTD |
PMID:27444704 PMID:28208728 PMID:29350491 |
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NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
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G
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Fus
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Fus RNA binding protein
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increases expression
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ISO
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butylparaben results in increased expression of FUS mRNA
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CTD |
PMID:17121429 |
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NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414
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G
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Fyn
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FYN proto-oncogene, Src family tyrosine kinase
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of FYN mRNA
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CTD |
PMID:25607892 |
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NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911
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G
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Gabra4
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gamma-aminobutyric acid type A receptor subunit alpha 4
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRA4 mRNA
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CTD |
PMID:25607892 |
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NCBI chr14:36,944,747...37,021,652
Ensembl chr14:36,590,782...36,665,844
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G
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Gabrb1
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gamma-aminobutyric acid type A receptor subunit beta1
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA
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CTD |
PMID:25607892 |
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NCBI chr14:36,434,339...36,917,920
Ensembl chr14:36,080,393...36,548,948
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G
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Gls
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glutaminase
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GLS mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GLS mRNA
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CTD |
PMID:25607892 |
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NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:49,344,781...49,416,900
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G
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Gper1
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G protein-coupled estrogen receptor 1
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increases expression
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ISO
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butylparaben results in increased expression of GPER1 mRNA; butylparaben results in increased expression of GPER1 protein
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CTD |
PMID:17121429 PMID:26253279 |
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NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889
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G
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Greb1
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growth regulating estrogen receptor binding 1
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multiple interactions increases expression
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ISO
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Fulvestrant inhibits the reaction [butylparaben metabolite results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of GREB1 mRNA] butylparaben metabolite results in increased expression of GREB1 mRNA; butylparaben results in increased expression of GREB1 mRNA
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CTD |
PMID:17121429 PMID:29945225 |
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NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:39,440,504...39,581,633
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G
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Gria2
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glutamate ionotropic receptor AMPA type subunit 2
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIA2 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510
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G
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Gria4
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glutamate ionotropic receptor AMPA type subunit 4
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIA4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIA4 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 8:9,845,421...10,320,021
Ensembl chr 8:1,562,119...2,034,979
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G
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Grid2
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glutamate ionotropic receptor delta type subunit 2
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multiple interactions
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EXP
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[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRID2 mRNA
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CTD |
PMID:34383603 |
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NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
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G
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Grik2
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glutamate ionotropic receptor kainate type subunit 2
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIK2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIK2 mRNA
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CTD |
PMID:25607892 |
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NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
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G
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Grik4
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glutamate ionotropic receptor kainate type subunit 4
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIK4 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751
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G
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Grik5
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glutamate ionotropic receptor kainate type subunit 5
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIK5 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:80,605,892...80,667,125
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G
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Grin1
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glutamate ionotropic receptor NMDA type subunit 1
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of GRIN1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIN1 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603
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G
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Grin2b
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glutamate ionotropic receptor NMDA type subunit 2B
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIN2B mRNA
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CTD |
PMID:25607892 |
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NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279
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G
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Grin2c
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glutamate ionotropic receptor NMDA type subunit 2C
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIN2C mRNA
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CTD |
PMID:25607892 |
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NCBI chr10:100,987,410...101,006,064
Ensembl chr10:100,488,431...100,506,427
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G
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Grin2d
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glutamate ionotropic receptor NMDA type subunit 2D
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIN2D mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of GRIN2D mRNA; [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRIN2D mRNA
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CTD |
PMID:25607892 PMID:34383603 |
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NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:96,308,365...96,344,793
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G
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Grin3a
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glutamate ionotropic receptor NMDA type subunit 3A
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIN3A mRNA
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CTD |
PMID:25607892 |
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NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085
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G
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Grip1
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glutamate receptor interacting protein 1
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIP1 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273
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G
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Gsk3b
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glycogen synthase kinase 3 beta
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decreases phosphorylation
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ISO
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butylparaben results in decreased phosphorylation of GSK3B protein
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CTD |
PMID:29319206 |
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NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646
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G
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Hes6
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hes family bHLH transcription factor 6
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of HES6 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
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G
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Hexb
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hexosaminidase subunit beta
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multiple interactions
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EXP
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zinc chloride inhibits the reaction [butylparaben results in increased secretion of HEXB protein]
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CTD |
PMID:15272608 |
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NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
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G
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Hps6
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HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
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increases expression
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ISO
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butylparaben results in increased expression of HPS6 mRNA
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CTD |
PMID:17121429 |
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NCBI chr 1:244,853,256...244,855,865
Ensembl chr 1:244,853,194...244,855,883
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G
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Hr
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HR, lysine demethylase and nuclear receptor corepressor
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of HR mRNA
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CTD |
PMID:25607892 |
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NCBI chr15:52,036,540...52,056,019
Ensembl chr15:45,626,835...45,646,313
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G
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Hsd17b10
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hydroxysteroid (17-beta) dehydrogenase 10
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of HSD17B10 mRNA
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CTD |
PMID:25607892 |
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NCBI chr X:24,568,551...24,571,012
Ensembl chr X:21,089,122...21,109,488
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G
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Hsd17b8
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hydroxysteroid (17-beta) dehydrogenase 8
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of HSD17B8 mRNA
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CTD |
PMID:25607892 |
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NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742
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G
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Hsd3b2
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hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of HSD3B6 mRNA
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CTD |
PMID:25607892 |
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NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:186,095,897...186,101,852
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G
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Hspa5
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heat shock protein family A (Hsp70) member 5
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increases expression
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ISO
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butylparaben results in increased expression of HSPA5 protein butylparaben results in increased expression of HSPA5 mRNA
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CTD |
PMID:29319206 PMID:36277366 |
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NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
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G
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Hspb8
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heat shock protein family B (small) member 8
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increases expression
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ISO
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butylparaben results in increased expression of HSPB8 mRNA
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CTD |
PMID:23524099 |
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NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
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G
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Igdcc3
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immunoglobulin superfamily, DCC subclass, member 3
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increases expression
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ISO
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butylparaben results in increased expression of IGDCC3 mRNA
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CTD |
PMID:17121429 |
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NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959
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G
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Igf1r
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insulin-like growth factor 1 receptor
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of IGF1R mRNA
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CTD |
PMID:25607892 |
|
NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777
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G
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Igf2r
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insulin-like growth factor 2 receptor
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of IGF2R mRNA
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CTD |
PMID:25607892 |
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NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
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G
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Il17rb
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interleukin 17 receptor B
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increases expression
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ISO
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butylparaben results in increased expression of IL17RB mRNA
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CTD |
PMID:17121429 |
|
NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
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G
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Il1rapl1
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interleukin 1 receptor accessory protein-like 1
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of IL1RAPL1 mRNA
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CTD |
PMID:25607892 |
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NCBI chr X:51,371,969...52,876,726
Ensembl chr X:51,378,215...52,876,772
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G
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Incenp
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inner centromere protein
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increases expression
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ISO
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butylparaben results in increased expression of INCENP mRNA
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CTD |
PMID:17121429 |
|
NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265
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G
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Ins2
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insulin 2
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multiple interactions
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ISO
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butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]
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CTD |
PMID:31016361 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775
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G
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Jag1
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jagged canonical Notch ligand 1
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multiple interactions
|
EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of JAG1 mRNA
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CTD |
PMID:25607892 |
|
NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209
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G
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Kcnc1
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potassium voltage-gated channel subfamily C member 1
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increases expression
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ISO
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butylparaben results in increased expression of KCNC1 mRNA
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CTD |
PMID:17121429 |
|
NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
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G
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Kcnf1
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potassium voltage-gated channel modifier subfamily F member 1
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increases expression
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ISO
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butylparaben results in increased expression of KCNF1 mRNA
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CTD |
PMID:17121429 |
|
NCBI chr 6:45,691,028...45,693,706
Ensembl chr 6:39,962,307...39,964,979
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G
|
Kiss1
|
KiSS-1 metastasis-suppressor
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of KISS1 mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
|
|
G
|
Kitlg
|
KIT ligand
|
increases expression
|
EXP
|
butylparaben results in increased expression of KITLG mRNA
|
CTD |
PMID:22777679 |
|
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
|
|
G
|
Kmt2d
|
lysine methyltransferase 2D
|
increases expression
|
ISO
|
butylparaben results in increased expression of KMT2D mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
|
|
G
|
Krt8
|
keratin 8
|
increases expression
|
ISO
|
butylparaben results in increased expression of KRT8 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
|
|
G
|
Krt82
|
keratin 82
|
increases expression
|
ISO
|
butylparaben results in increased expression of KRT82 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 7:132,665,506...132,675,362
Ensembl chr 7:132,665,292...132,675,489
|
|
G
|
Lef1
|
lymphoid enhancer binding factor 1
|
increases expression
|
ISO
|
butylparaben results in increased expression of LEF1 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:219,666,592...219,779,794
|
|
G
|
Lep
|
leptin
|
decreases expression increases expression
|
ISO
|
butylparaben results in decreased expression of LEP mRNA butylparaben results in increased expression of LEP mRNA
|
CTD |
PMID:22956630 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262
|
|
G
|
Lhb
|
luteinizing hormone subunit beta
|
multiple interactions decreases expression decreases secretion
|
EXP
|
butylparaben promotes the reaction [Triclosan results in decreased secretion of LHB protein]; Triclosan promotes the reaction [butylparaben results in decreased secretion of LHB protein] butylparaben results in decreased expression of LHB protein
|
CTD |
PMID:27444704 PMID:29350491 |
|
NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
|
|
G
|
Lin7a
|
lin-7 homolog A, crumbs cell polarity complex component
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of LIN7A mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
|
|
G
|
Lmod1
|
leiomodin 1
|
increases expression
|
ISO
|
butylparaben results in increased expression of LMOD1 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
|
|
G
|
Lpin1
|
lipin 1
|
multiple interactions increases expression
|
ISO
|
[Dexamethasone co-treated with butylparaben] results in increased expression of LPIN1 mRNA; NR3C1 mutant form inhibits the reaction [butylparaben results in increased expression of LPIN1 mRNA]
|
CTD |
PMID:22956630 |
|
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
|
|
G
|
Lrrc29
|
leucine rich repeat containing 29
|
increases expression
|
ISO
|
butylparaben results in increased expression of FBXL9P mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr19:33,181,713...33,203,583
Ensembl chr19:33,188,352...33,203,545
|
|
G
|
Magi2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MAGI2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MAGI2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:14,386,399...15,870,240
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
increases phosphorylation
|
ISO
|
butylparaben results in increased phosphorylation of MAPK1 protein
|
CTD |
PMID:26253279 PMID:29319206 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
increases phosphorylation
|
ISO
|
butylparaben results in increased phosphorylation of MAPK3 protein
|
CTD |
PMID:26253279 PMID:29319206 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Masp1
|
MBL associated serine protease 1
|
increases expression
|
ISO
|
butylparaben results in increased expression of MASP1 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr11:90,839,081...90,909,922
Ensembl chr11:77,334,859...77,402,974
|
|
G
|
Mdga2
|
MAM domain containing glycosylphosphatidylinositol anchor 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MDGA2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MDGA2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 6:84,746,422...85,608,640
Ensembl chr 6:84,761,941...85,608,126
|
|
G
|
Met
|
MET proto-oncogene, receptor tyrosine kinase
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MET mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876
|
|
G
|
Mmp3
|
matrix metallopeptidase 3
|
multiple interactions
|
EXP
|
[enzacamene co-treated with octylmethoxycinnamate co-treated with bisphenol A co-treated with butylparaben] results in increased expression of MMP3 mRNA
|
CTD |
PMID:25305543 |
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961
|
|
G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases expression multiple interactions
|
ISO
|
butylparaben results in increased expression of MYC mRNA [butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer]; [NRG1 protein co-treated with butylparaben] results in increased expression of MYC protein; butylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA]; NRG1 protein promotes the reaction [butylparaben results in increased expression of MYC mRNA]
|
CTD |
PMID:26502914 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
|
|
G
|
Ncoa2
|
nuclear receptor coactivator 2
|
multiple interactions
|
ISO
|
butylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]]
|
CTD |
PMID:23583298 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
|
|
G
|
Nf1
|
neurofibromin 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of NF1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NF1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658
|
|
G
|
Nlgn1
|
neuroligin 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NLGN1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NLGN1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of NLGN1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:108,257,824...109,002,464
|
|
G
|
Notch2
|
notch receptor 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:185,610,589...185,744,088
|
|
G
|
Notch4
|
notch receptor 4
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NOTCH4 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NOTCH4 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
|
|
G
|
Nr1i2
|
nuclear receptor subfamily 1, group I, member 2
|
increases expression
|
EXP ISO
|
butylparaben results in increased expression of NR1I2 mRNA
|
CTD |
PMID:31472229 |
|
NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658
|
|
G
|
Nr1i3
|
nuclear receptor subfamily 1, group I, member 3
|
increases expression
|
EXP
|
butylparaben results in increased expression of NR1I3 mRNA
|
CTD |
PMID:31472229 |
|
NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906
|
|
G
|
Nr3c1
|
nuclear receptor subfamily 3, group C, member 1
|
multiple interactions increases response to substance increases activity
|
ISO EXP
|
NR3C1 mutant form inhibits the reaction [butylparaben results in increased expression of LPIN1 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA]; NR3C1 protein promotes the reaction [butylparaben results in decreased expression of SPP1 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA]; NR3C1 protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA] NR3C1 protein results in increased susceptibility to butylparaben [butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin co-treated with propylparaben] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben co-treated with tetramethrin] results in increased activity of NR3C1 protein; [Diethylhexyl Phthalate co-treated with butylparaben] results in increased activity of NR3C1 protein butylparaben results in increased activity of NR3C1 protein [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of NR3C1 mRNA
|
CTD |
PMID:22956630 PMID:25448277 PMID:28527915 PMID:34383603 |
|
NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375
|
|
G
|
Nr3c2
|
nuclear receptor subfamily 3, group C, member 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NR3C2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885
|
|
G
|
Nr5a1
|
nuclear receptor subfamily 5, group A, member 1
|
decreases expression
|
EXP
|
butylparaben results in decreased expression of NR5A1 mRNA
|
CTD |
PMID:27122241 |
|
NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:22,465,502...22,486,328
|
|
G
|
Nrcam
|
neuronal cell adhesion molecule
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NRCAM mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
|
|
G
|
Nrg1
|
neuregulin 1
|
multiple interactions
|
EXP ISO
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of NRG1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NRG1 mRNA [butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer]; [NRG1 protein co-treated with butylparaben] results in increased expression of MYC protein; butylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA]; NRG1 protein promotes the reaction [butylparaben results in increased expression of MYC mRNA]
|
CTD |
PMID:25607892 PMID:26502914 |
|
NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884
|
|
G
|
Nrxn1
|
neurexin 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NRXN1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:3,177,897...4,322,710
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|
G
|
Nrxn2
|
neurexin 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NRXN2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NRXN2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:203,735,753...203,842,297
|
|
G
|
Ntrk1
|
neurotrophic receptor tyrosine kinase 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NTRK1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770
|
|
G
|
Ntrk2
|
neurotrophic receptor tyrosine kinase 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of NTRK2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of NTRK2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136
|
|
G
|
Ntrk3
|
neurotrophic receptor tyrosine kinase 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of NTRK3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of NTRK3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:132,132,849...132,503,286
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G
|
Nxph3
|
neurexophilin 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of NXPH3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:80,456,283...80,459,949
Ensembl chr10:80,455,429...80,462,415
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|
G
|
Otof
|
otoferlin
|
increases expression
|
ISO
|
butylparaben results in increased expression of OTOF mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 6:25,928,018...26,024,631
Ensembl chr 6:25,928,055...26,024,631
|
|
G
|
Oxt
|
oxytocin/neurophysin I prepropeptide
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of OXT mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:117,782,650...117,783,490
|
|
G
|
Pcdha3
|
protocadherin alpha 3
|
increases expression
|
ISO
|
butylparaben results in increased expression of PCDHA3 mRNA
|
CTD |
PMID:17121429 |
|
Ensembl chr18:28,581,225...28,846,211
|
|
G
|
Pcdhgc3
|
protocadherin gamma subfamily C, 3
|
increases expression
|
ISO
|
butylparaben results in increased expression of PCDHGC3 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868
|
|
G
|
Pex14
|
peroxisomal biogenesis factor 14
|
increases expression
|
ISO
|
butylparaben results in increased expression of PEX14 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 5:164,682,876...164,819,352
Ensembl chr 5:159,399,776...159,536,272
|
|
G
|
Pgr
|
progesterone receptor
|
multiple interactions increases expression
|
EXP ISO
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PGR mRNA; Fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR protein] butylparaben results in increased expression of PGR mRNA; butylparaben results in increased expression of PGR protein Silver inhibits the reaction [butylparaben results in increased expression of PGR mRNA]
|
CTD |
PMID:17121429 PMID:19654335 PMID:23524099 PMID:25128701 PMID:25607892 PMID:29074358 More...
|
|
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
|
|
G
|
Pi4ka
|
phosphatidylinositol 4-kinase alpha
|
increases expression
|
ISO
|
butylparaben results in increased expression of PI4KA mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr11:83,609,148...83,726,876
Ensembl chr11:83,609,069...83,724,080
|
|
G
|
Plin1
|
perilipin 1
|
increases expression multiple interactions
|
ISO
|
butylparaben results in increased expression of PLIN1 mRNA NR3C1 protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of PLIN1 mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA]
|
CTD |
PMID:22956630 PMID:28527915 |
|
NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:133,664,892...133,676,828
|
|
G
|
Pomc
|
proopiomelanocortin
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of POMC mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
increases expression
|
EXP
|
butylparaben results in increased expression of PPARA mRNA
|
CTD |
PMID:31472229 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
increases expression multiple interactions increases activity increases response to substance
|
ISO
|
butylparaben results in increased expression of PPARG mRNA 2-chloro-5-nitrobenzanilide inhibits the reaction [butylparaben results in increased expression of PPARG mRNA]; bisphenol A diglycidyl ether inhibits the reaction [butylparaben results in increased expression of PPARG mRNA]; butylparaben promotes the reaction [Dexamethasone results in increased expression of PPARG mRNA]; Mifepristone inhibits the reaction [butylparaben results in increased expression of PPARG mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG mutant form inhibits the reaction [butylparaben results in increased expression of PLIN1 mRNA]; PPARG protein inhibits the reaction [butylparaben results in decreased expression of SPP1 mRNA]; PPARG protein promotes the reaction [butylparaben binds to and results in increased activity of PPARG protein]; PPARG protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of CEBPA mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of FABP4 mRNA]; PPARG protein promotes the reaction [butylparaben results in increased expression of PLIN1 mRNA] butylparaben results in increased activity of PPARG protein PPARG protein results in increased susceptibility to butylparaben
|
CTD |
PMID:22956630 PMID:24155963 PMID:27659731 PMID:28527915 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
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|
G
|
Ppp1r1b
|
protein phosphatase 1, regulatory (inhibitor) subunit 1B
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of PPP1R1B mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,347,731...83,356,775
|
|
G
|
Prkn
|
parkin RBR E3 ubiquitin protein ligase
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555
|
|
G
|
Prlr
|
prolactin receptor
|
increases expression
|
ISO
|
butylparaben results in increased expression of PRLR mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:59,134,588...59,324,718
|
|
G
|
Pyroxd2
|
pyridine nucleotide-disulphide oxidoreductase domain 2
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of PYROXD2 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 1:241,523,278...241,549,083
Ensembl chr 1:241,523,377...241,548,761
|
|
G
|
Reln
|
reelin
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of RELN mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:12,736,130...13,162,211
|
|
G
|
Robo1
|
roundabout guidance receptor 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of ROBO1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr11:24,067,869...25,108,694
Ensembl chr11:10,580,908...11,620,203
|
|
G
|
Rps6
|
ribosomal protein S6
|
multiple interactions decreases phosphorylation
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [butylparaben results in decreased phosphorylation of RPS6 protein]
|
CTD |
PMID:29319206 |
|
NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
|
|
G
|
Rps6kb1
|
ribosomal protein S6 kinase B1
|
decreases phosphorylation multiple interactions
|
ISO
|
butylparaben results in decreased phosphorylation of RPS6KB1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein]; U 0126 inhibits the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein]
|
CTD |
PMID:29319206 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908
|
|
G
|
Runx2
|
RUNX family transcription factor 2
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of RUNX2 mRNA
|
CTD |
PMID:28527915 |
|
NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167
|
|
G
|
S100g
|
S100 calcium binding protein G
|
multiple interactions increases expression
|
EXP
|
Fulvestrant inhibits the reaction [butylparaben results in increased expression of S100G mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of S100G protein] butylparaben results in increased expression of S100G mRNA; butylparaben results in increased expression of S100G protein
|
CTD |
PMID:19654335 PMID:22777679 |
|
NCBI chr X:31,705,853...31,708,422
Ensembl chr X:31,705,866...31,708,433
|
|
G
|
Shank1
|
SH3 and multiple ankyrin repeat domains 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SHANK1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SHANK1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:94,807,879...94,857,356
Ensembl chr 1:94,808,276...94,855,824
|
|
G
|
Shank2
|
SH3 and multiple ankyrin repeat domains 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of SHANK2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SHANK2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:199,169,429...199,589,394
|
|
G
|
Shank3
|
SH3 and multiple ankyrin repeat domains 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SHANK3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:120,570,402...120,630,374
|
|
G
|
Shbg
|
sex hormone binding globulin
|
decreases secretion
|
ISO
|
butylparaben results in decreased secretion of SHBG protein
|
CTD |
PMID:30940137 |
|
NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057
|
|
G
|
Siah2
|
siah E3 ubiquitin protein ligase 2
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of SIAH2 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
|
|
G
|
Slc17a7
|
solute carrier family 17 member 7
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC17A7 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:104,786,172...104,798,049
Ensembl chr 1:95,649,745...95,661,588
|
|
G
|
Slc1a1
|
solute carrier family 1 member 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:226,549,842...226,630,402
|
|
G
|
Slc1a2
|
solute carrier family 1 member 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SLC1A2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:89,005,129...89,126,498
|
|
G
|
Slc1a3
|
solute carrier family 1 member 3
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A3 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SLC1A3 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:57,755,497...57,830,605
|
|
G
|
Slc1a6
|
solute carrier family 1 member 6
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of SLC1A6 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449
|
|
G
|
Slc22a2
|
solute carrier family 22 member 2
|
multiple interactions
|
ISO
|
butylparaben inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
|
CTD |
PMID:21599003 |
|
NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:48,121,061...48,163,268
|
|
G
|
Slit1
|
slit guidance ligand 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SLIT1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SLIT1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
|
|
G
|
Smc1a
|
structural maintenance of chromosomes 1A
|
increases expression
|
ISO
|
butylparaben results in increased expression of SMC1A mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056
|
|
G
|
Sox15
|
SRY-box transcription factor 15
|
increases expression
|
ISO
|
butylparaben results in increased expression of SOX15 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr10:54,871,793...54,873,497
Ensembl chr10:54,372,403...54,376,591
|
|
G
|
Spp1
|
secreted phosphoprotein 1
|
multiple interactions decreases expression
|
ISO
|
NR3C1 protein promotes the reaction [butylparaben results in decreased expression of SPP1 mRNA]; PPARG protein inhibits the reaction [butylparaben results in decreased expression of SPP1 mRNA]
|
CTD |
PMID:28527915 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162
|
|
G
|
Sptbn2
|
spectrin, beta, non-erythrocytic 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SPTBN2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283
|
|
G
|
Star
|
steroidogenic acute regulatory protein
|
decreases expression increases expression
|
EXP
|
butylparaben results in decreased expression of STAR mRNA; butylparaben results in decreased expression of STAR protein butylparaben results in increased expression of STAR mRNA
|
CTD |
PMID:18648085 PMID:22777679 PMID:26888303 |
|
NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672
|
|
G
|
Stmn2
|
stathmin 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of STMN2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:93,204,692...93,252,011
|
|
G
|
Sts
|
steroid sulfatase
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of STS mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of STS mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402
|
|
G
|
Stx1b
|
syntaxin 1B
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of STX1B mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
|
|
G
|
Stxbp1
|
syntaxin binding protein 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of STXBP1 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of STXBP1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 3:36,474,428...36,536,120
Ensembl chr 3:16,076,391...16,138,369
|
|
G
|
Sult1e1
|
sulfotransferase family 1E member 1
|
decreases expression
|
EXP
|
butylparaben results in decreased expression of SULT1E1 mRNA; butylparaben results in decreased expression of SULT1E1 protein
|
CTD |
PMID:26888303 |
|
NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,422,324...20,439,275
|
|
G
|
Syngap1
|
synaptic Ras GTPase activating protein 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of SYNGAP1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672
|
|
G
|
Syp
|
synaptophysin
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SYP mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr X:17,521,348...17,536,449
Ensembl chr X:14,849,444...14,864,745
|
|
G
|
Syt6
|
synaptotagmin 6
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of SYT6 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 2:191,093,009...191,152,283
Ensembl chr 2:191,093,007...191,149,956
|
|
G
|
Tcea3
|
transcription elongation factor A3
|
increases expression
|
ISO
|
butylparaben results in increased expression of TCEA3 mRNA
|
CTD |
PMID:17121429 |
|
NCBI chr 5:148,476,941...148,509,452
Ensembl chr 5:148,476,941...148,509,448
|
|
G
|
Tfap2b
|
transcription factor AP-2 beta
|
increases expression
|
ISO
|
butylparaben results in increased expression of TFAP2B mRNA
|
CTD |
PMID:37690743 |
|
NCBI chr 9:29,282,703...29,312,568
Ensembl chr 9:21,786,258...21,814,520
|
|
G
|
Tff1
|
trefoil factor 1
|
multiple interactions increases expression
|
ISO
|
Fulvestrant inhibits the reaction [butylparaben results in increased expression of TFF1 mRNA]; Silver inhibits the reaction [butylparaben results in increased expression of TFF1 mRNA]
|
CTD |
PMID:16797915 PMID:17121429 PMID:22562034 PMID:23524099 PMID:29074358 |
|
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
|
|
G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of TGFB1 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
|
|
G
|
Th
|
tyrosine hydroxylase
|
multiple interactions
|
EXP
|
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA
|
CTD |
PMID:34383603 |
|
NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767
|
|
G
|
Tnfrsf10b
|
TNF receptor superfamily member 10b
|
increases expression
|
ISO
|
butylparaben results in increased expression of TNFRSF10A mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
|
|
G
|
Tnfrsf11b
|
TNF receptor superfamily member 11B
|
multiple interactions
|
ISO
|
butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]
|
CTD |
PMID:31016361 |
|
NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:85,566,520...85,594,538
|
|
G
|
Tnfrsf1a
|
TNF receptor superfamily member 1A
|
increases expression
|
ISO
|
butylparaben results in increased expression of TNFRSF1A mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591
|
|
G
|
Tnfrsf21
|
TNF receptor superfamily member 21
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of TNFRSF21 mRNA
|
CTD |
PMID:24481588 |
|
NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085
|
|
G
|
Tpo
|
thyroid peroxidase
|
increases expression increases activity
|
EXP
|
butylparaben results in increased expression of TPO mRNA butylparaben results in increased activity of TPO protein
|
CTD |
PMID:32798586 |
|
NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:46,698,414...46,768,199
|
|
G
|
Tsc2
|
TSC complex subunit 2
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of TSC2 mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of TSC2 mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951
|
|
G
|
Tshb
|
thyroid stimulating hormone subunit beta
|
increases expression
|
EXP
|
butylparaben results in increased expression of TSHB protein
|
CTD |
PMID:32798586 |
|
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
|
|
G
|
Tsnax
|
translin-associated factor X
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of TSNAX mRNA
|
CTD |
PMID:25607892 |
|
NCBI chr19:52,975,848...52,989,886
Ensembl chr19:52,975,659...52,989,878
|
|
G
|
Tspo
|
translocator protein
|
decreases expression
|
EXP
|
butylparaben results in decreased expression of TSPO mRNA
|
CTD |
PMID:18648085 |
|
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
|
|
G
|
Ubd
|
ubiquitin D
|
decreases expression
|
ISO
|
butylparaben results in decreased expression of UBD mRNA
|
CTD |
PMID:17121429 |
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NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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G
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Unc5a
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unc-5 netrin receptor A
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of UNC5A mRNA
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CTD |
PMID:25607892 |
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NCBI chr17:9,614,841...9,670,558
Ensembl chr17:9,614,838...9,670,526
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G
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Unc5b
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unc-5 netrin receptor B
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of UNC5B mRNA
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CTD |
PMID:25607892 |
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NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
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G
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Unc5c
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unc-5 netrin receptor C
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of UNC5C mRNA; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of UNC5C mRNA
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CTD |
PMID:25607892 |
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NCBI chr 2:230,180,353...230,535,219
Ensembl chr 2:230,180,951...230,535,217
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G
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Vegfa
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vascular endothelial growth factor A
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of VEGFA mRNA
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CTD |
PMID:25607892 |
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NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641
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G
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Vill
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villin-like
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increases expression
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ISO
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butylparaben results in increased expression of VILL mRNA
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CTD |
PMID:17121429 |
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NCBI chr 8:118,776,718...118,794,983
Ensembl chr 8:118,776,742...118,794,983
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G
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Vldlr
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very low density lipoprotein receptor
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multiple interactions
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EXP
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[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of VLDLR mRNA
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CTD |
PMID:25607892 |
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NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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G
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Wnk4
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WNK lysine deficient protein kinase 4
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increases expression
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ISO
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butylparaben results in increased expression of WNK4 mRNA
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CTD |
PMID:17121429 |
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NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
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G
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Xbp1
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X-box binding protein 1
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increases expression
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ISO
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butylparaben results in increased expression of XBP1 mRNA; butylparaben results in increased expression of XBP1 mRNA alternative form
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CTD |
PMID:36277366 |
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NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693
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G
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Zfp397
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zinc finger protein 397
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increases expression
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ISO
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butylparaben results in increased expression of ZNF397 mRNA
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CTD |
PMID:17121429 |
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NCBI chr18:15,241,764...15,253,148
Ensembl chr18:15,242,096...15,300,984
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