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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:rheumatoid arthritis
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Accession:DOID:7148 term browser browse the term
Definition:An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint. (DO)
Synonyms:exact_synonym: RA;   atrophic arthritis;   rheumatic arthritis or polyarthritis
 narrow_synonym: ACPA-negative rheumatoid arthritis;   ACPA-positive rheumatoid arthritis;   RHEUMATOID ARTHRITIS, PROGRESSION OF;   SLC22A4-RELATED CONDITION
 related_synonym: rheumatoid arthritis, susceptibility to
 primary_id: MESH:D001172
 alt_id: MIM:180300
 xref: EFO:0000685;   EFO:0009459;   EFO:0009460;   ICD10CM:M06.9;   ICD9CM:714.0;   NCI:C2884
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin IEA GAD PMID:15118671 RGD:1331525 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20080907 PMID:22104130 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 3:183,919,934...184,017,884
Ensembl chr 3:183,919,934...184,017,939 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ACAN aggrecan disease_progression IEP
EXP		 protein:increased degradation:cartilage
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15292528 PMID:16507130 RGD:11570537 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353 		JBrowse link
G ACKR3 atypical chemokine receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 2:236,537,122...236,582,354
Ensembl chr 2:236,567,787...236,582,354 		JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 IEP mRNA:increased expression:synovium RGD PMID:11801682 RGD:10043106 NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 IEP protein:alternative form:synovium RGD PMID:11801682 RGD:10043106 NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing IEP
EXP		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12833524 PMID:21789720 RGD:5686424 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADORA2A adenosine A2a receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G ADRB3 adrenoceptor beta 3 IAGP DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:12739037 RGD:5684893 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AFF3 ALF transcription elongation factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 2:99,545,419...100,142,590
Ensembl chr 2:99,545,419...100,192,428 		JBrowse link
G AGER advanced glycosylation end-product specific receptor IEP
EXP		 protein:decreased expression:plasma (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16385501 PMID:20541603 RGD:7244141 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AHR aryl hydrocarbon receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:18617548 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ANG angiogenin IEP RGD PMID:12653852 RGD:6892721 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANKRD55 ankyrin repeat domain 55 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 5:56,099,680...56,233,330
Ensembl chr 5:56,099,680...56,233,330 		JBrowse link
G ANXA3 annexin A3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451 		JBrowse link
G AP4B1-AS1 AP4B1 antisense RNA 1 IAGP ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO
ClinVar Annotator: match by term: Rheumatoid arthritis		 ClinVar PMID:15004560 PMID:15208781 PMID:15273934 PMID:15580548 PMID:15719322 More... NCBI chr 1:113,812,612...113,901,237
Ensembl chr 1:113,812,379...113,901,237 		JBrowse link
G APOA4 apolipoprotein A4 IEP protein:increased expression:blood serum (human) RGD PMID:20367977 RGD:5685646 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304 		JBrowse link
G ARID5B AT-rich interaction domain 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 PMID:23143596 NCBI chr10:61,901,699...62,096,944
Ensembl chr10:61,901,684...62,096,944 		JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19193698 NCBI chr 2:215,312,059...215,368,592
Ensembl chr 2:215,311,956...215,349,773 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA:decreased expression:liver RGD PMID:18372237 RGD:153352318 NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042 		JBrowse link
G B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 2:62,196,115...62,224,731
Ensembl chr 2:62,196,115...62,224,731 		JBrowse link
G B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr16:67,148,104...67,150,998
Ensembl chr16:67,148,104...67,150,998 		JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 7:98,291,650...98,401,090
Ensembl chr 7:98,291,650...98,401,090 		JBrowse link
G BCL2A1 BCL2 related protein A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196 		JBrowse link
G BDKRB2 bradykinin receptor B2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IDA
IEP		 protein:increased expression:serum RGD PMID:22447331 PMID:3488088 RGD:6483593, RGD:6483600 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317 		JBrowse link
G BGN biglycan EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr  X:153,494,980...153,509,546
Ensembl chr  X:153,494,980...153,509,546 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 8:11,494,387...11,564,599
Ensembl chr 8:11,486,894...11,564,599 		JBrowse link
G BMP4 bone morphogenetic protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP6 bone morphogenetic protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BTNL2 butyrophilin like 2 susceptibility IAGP DNA:SNPs: : RGD PMID:23364395 RGD:9685033 NCBI chr 6:32,393,339...32,407,181
Ensembl chr 6:32,393,339...32,407,181 		JBrowse link
G C3 complement C3 IEP RGD PMID:7561187 RGD:11040775 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C4B complement C4B (Chido/Rodgers blood group) IAGP RGD PMID:22076784 RGD:5688263 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418 		JBrowse link
G CA1 carbonic anhydrase 1 IDA RGD PMID:12806141 RGD:408425977 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 IDA RGD PMID:12806141 RGD:408425977 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
G CALD1 caldesmon 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729 		JBrowse link
G CASP7 caspase 7 IEP RGD PMID:18785314 RGD:5684540 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CAST calpastatin IDA RGD PMID:7706496 RGD:5683620 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV2 caveolin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:116,499,738...116,508,541
Ensembl chr 7:116,287,380...116,508,541 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 IEP protein:increased expression:serum RGD PMID:20056091 RGD:4891442 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL21 C-C motif chemokine ligand 21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chr 9:34,709,005...34,710,136
Ensembl chr 9:34,709,005...34,710,136 		JBrowse link
G CCL22 C-C motif chemokine ligand 22 IEP protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189 		JBrowse link
G CCL8 C-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402 		JBrowse link
G CCN1 cellular communication network factor 1 EXP
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (human)		 CTD
RGD		 PMID:19192274 PMID:34031328 RGD:329845561 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCN2 cellular communication network factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 IMP RGD PMID:12860725 RGD:5688170 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 IEP protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 IEP protein:increased expression:synovial membrane:
mRNA:increased expression:synovium:		 RGD PMID:19942450 PMID:25430645 RGD:10054497, RGD:10054499 NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,957,120 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 resistance
no_association		 IAGP DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) RGD PMID:16541097 PMID:17565662 RGD:1626290, RGD:1626283 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453841 PMID:20453842 PMID:23143596 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141 		JBrowse link
G CD2 CD2 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:116,754,430...116,769,229
Ensembl chr 1:116,754,430...116,769,229 		JBrowse link
G CD244 CD244 molecule susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:18794858 NCBI chr 1:160,830,160...160,862,887
Ensembl chr 1:160,830,160...160,862,887 		JBrowse link
G CD28 CD28 molecule IEP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19898481 PMID:20453842 PMID:23143596 PMID:19075187 RGD:5131619 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175 		JBrowse link
G CD40 CD40 molecule IAGP
EXP		 DNA:SNP: :rs4810485 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18794853 PMID:20453842 PMID:23143596 PMID:20498205 RGD:5490972 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD5 CD5 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr11:61,093,963...61,127,852
Ensembl chr11:61,102,489...61,127,852 		JBrowse link
G CD80 CD80 molecule IEP protein:increased expression:serum RGD PMID:22917707 RGD:6893647 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614 		JBrowse link
G CD83 CD83 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,140,682 		JBrowse link
G CDK6 cyclin dependent kinase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794853 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta IEP protein:increased expression:knee, articular cartilage (human) RGD PMID:19248099 RGD:10401213 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CHI3L1 chitinase 3 like 1 severity IEP protein:increased secretion:serum (human) RGD PMID:10461474 RGD:4892605 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO mRNA,protein:increased expression:joint, spleen: RGD PMID:31279484 RGD:151676715 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018 		JBrowse link
G CHRNG cholinergic receptor nicotinic gamma subunit IAGP ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:23261301 PMID:25741868 PMID:28492532 NCBI chr 2:232,539,692...232,548,115
Ensembl chr 2:232,539,692...232,548,115 		JBrowse link
G CIITA class II major histocompatibility complex transactivator susceptibility
no_association		 IAGP
EXP		 DNA:haplotype:promoter/CDS:rs3087456G/rs4774C
ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-168A>G
DNA:polymorphism:promoter:rs3087456, no association in a German cohort		 OMIM
ClinVar
CTD
RGD		 PMID:15821736 PMID:16849401 PMID:25741868 PMID:28492532 PMID:19221398 More... RGD:5491176, RGD:1358146, RGD:5491189 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021 		JBrowse link
G CLEC12A C-type lectin domain family 12 member A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr12:9,951,268...10,006,150
Ensembl chr12:9,951,316...9,995,694 		JBrowse link
G CLEC16A C-type lectin domain containing 16A IAGP DNA:polymorphism:intron:rs6498169G RGD PMID:19221398 RGD:5491176 NCBI chr16:10,944,564...11,182,186
Ensembl chr16:10,944,539...11,182,186 		JBrowse link
G COL2A1 collagen type II alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:27028940 PMID:29935983 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554 		JBrowse link
G CP ceruloplasmin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CRP C-reactive protein IEP
EXP
ISO		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:1568518 PMID:22173958 PMID:22173958 RGD:6904209, RGD:6904209 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF2 colony stimulating factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CTSD cathepsin D EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 IEP RGD PMID:11465708 RGD:4892002 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 PMID:19192274 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 IEP protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYBB cytochrome b-245 beta chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:24313545 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DDX6 DEAD-box helicase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr11:118,747,763...118,791,744
Ensembl chr11:118,747,763...118,791,164 		JBrowse link
G DHFR dihydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983 		JBrowse link
G DNASE1L3 deoxyribonuclease 1L3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 PMID:30224649 NCBI chr 3:58,192,257...58,210,972
Ensembl chr 3:58,192,257...58,214,697 		JBrowse link
G DNASE2 deoxyribonuclease 2, lysosomal ISS OMIM:180300 MouseDO NCBI chr19:12,875,209...12,881,449
Ensembl chr19:12,875,209...12,881,595 		JBrowse link
G DNMT1 DNA methyltransferase 1 severity IEP mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression IAGP DNA:polymorphism:promoter:-283C>T(human) RGD PMID:19777235 RGD:9589110 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G EDN1 endothelin 1 treatment IDA RGD PMID:22249931 RGD:8661695 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G ELN elastin IDA RGD PMID:12643515 RGD:9585739 NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G ENO1 enolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19898480 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 IEP protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 IEP mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:36104638 RGD:155791669 NCBI chr 8:27,771,974...27,819,660
Ensembl chr 8:27,771,949...27,812,640 		JBrowse link
G ESR2 estrogen receptor 2 severity IAGP DNA:SNP:exon:rs1256049(human) RGD PMID:21523342 RGD:5508794 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F2 coagulation factor II, thrombin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP
IMP
IEP		 DNA:snp:promoter:g.-670A>G (human)
protein:increased expression:serum (human)		 RGD PMID:23053964 PMID:20875116 PMID:12148596 RGD:8662433, RGD:12903969, RGD:8662455 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FCGR1A Fc gamma receptor Ia IEP protein:increased expression:synovial joint: RGD PMID:16670289 RGD:9685708 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675 		JBrowse link
G FCGR2A Fc gamma receptor IIa IAGP
EXP
IDA		 DNA:polymorphism: :p.H131R (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20453842 PMID:23143596 PMID:12508778 PMID:8254199 RGD:5147978, RGD:5147984 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G FCGR3A Fc gamma receptor IIIa susceptibility IAGP
IEP		 DNA:polymorphism:exon:p.F158V(rs396991)(human)
DNA:CNVs
protein:decreased expression:NK cell		 RGD PMID:19019892 PMID:25154742 PMID:15334114 RGD:5508391, RGD:11344974, RGD:5508467 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G FOXO3 forkhead box O3 IEP mRNA,protein:increased expression:peripheral blood mononuclear cell, polymorphonuclear cell,synovium: RGD PMID:19435720 RGD:10402186 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G FOXP3 forkhead box P3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20476861 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FPGS folylpolyglutamate synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 9:127,802,858...127,814,506
Ensembl chr 9:127,794,597...127,814,494 		JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr21:33,503,931...33,542,893
Ensembl chr21:33,503,931...33,543,491 		JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198 		JBrowse link
G GC GC vitamin D binding protein IEP
EXP		 protein:decreased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:3874814 PMID:9548303 RGD:5509931 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
G GDF5 growth differentiation factor 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18830904 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746 		JBrowse link
G GGH gamma-glutamyl hydrolase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 8:63,015,079...63,038,806
Ensembl chr 8:63,014,881...63,039,407 		JBrowse link
G GIN1 gypsy retrotransposon integrase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 5:103,086,000...103,120,138
Ensembl chr 5:103,086,000...103,120,138 		JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr12:12,891,562...12,917,937
Ensembl chr12:12,890,782...12,917,937 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO
EXP
IEP		 DNA: deletion: : heterozygous
CTD Direct Evidence: marker/mechanism
protein: decreased expression: mononuclear leukocytes		 CTD
RGD		 PMID:10094932 PMID:18662895 PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 no_association ISO
IEP		 DNA: deletion::GRK2 and GRK6 deletions resulted in more severe arthritis
protein: : mononuclear blood cells		 RGD PMID:18662895 PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745 		JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO
EXP
IEP		 DNA: deletion: : homozygous
CTD Direct Evidence: marker/mechanism
protein: decreased expression: mononuclear leukocytes		 CTD
RGD		 PMID:10094932 PMID:18662895 PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr 5:177,425,523...177,442,891
Ensembl chr 5:177,403,204...177,442,901 		JBrowse link
G GSDME gasdermin E EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion: :
DNA:deletion: : 		RGD PMID:16887863 PMID:15940757 PMID:16870093 RGD:5490993, RGD:5490998, RGD:5490994 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 severity
susceptibility		 IAGP DNA:deletion: : RGD PMID:19473562 PMID:20401725 PMID:20597111 RGD:5490553, RGD:5490983, RGD:5490982
G HAPLN1 hyaluronan and proteoglycan link protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 5:83,637,805...83,720,855
Ensembl chr 5:83,637,805...83,720,855 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 3:121,631,399...121,660,903
Ensembl chr 3:121,631,399...121,660,927 		JBrowse link
G HDAC1 histone deacetylase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32289289 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HFE homeostatic iron regulator IAGP DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,226...26,098,343 		JBrowse link
G HGF hepatocyte growth factor disease_progression IEP protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17956852 PMID:22286218 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP DNA:polymorphisms (human)
DNA:polymorphism (human)		 RGD PMID:11482129 PMID:11454644 RGD:5147859, RGD:5147860 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 6:32,741,391...32,747,198
Ensembl chr 6:32,741,391...32,747,198 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphism (human) RGD PMID:11454644 RGD:5147860 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP
EXP		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
DNA:polymorphisms (human)
DNA:polymorphisms: :multiple (human)		 CTD
RGD		 PMID:19898480 PMID:20453842 PMID:22286218 PMID:18512783 PMID:11454644 More... RGD:4144826, RGD:5147860, RGD:5147616, RGD:5147567 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO RGD PMID:18025202 RGD:9685481 NCBI chr 7:26,189,927...26,200,746
Ensembl chr 7:26,171,151...26,201,529 		JBrowse link
G HOXD10 homeobox D10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:176,116,778...176,119,937
Ensembl chr 2:176,108,790...176,119,937 		JBrowse link
G HOXD11 homeobox D11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:176,107,280...176,115,679
Ensembl chr 2:176,104,216...176,109,754 		JBrowse link
G HOXD13 homeobox D13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:176,087,487...176,095,944
Ensembl chr 2:176,092,721...176,095,944 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 IEP mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 IEP protein:increased expression:peripheral blood lymphocyte (human) RGD PMID:22047640 RGD:5688784 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 IEP protein:increased expression:synovial joint RGD PMID:11315915 RGD:5685639 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 IEP protein:increased expression:synovial cell: RGD PMID:23739258 RGD:10402561 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 IEP protein:increased expression:serum: RGD PMID:21417552 RGD:10402843 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 IEP mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IFNG interferon gamma treatment IDA
IEP
EXP		 mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22450443 PMID:1417133 PMID:22660635 RGD:8157623, RGD:155663483 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF2 insulin like growth factor 2 IAGP
IEP		 DNA:loss of imprinting:synovial cell
protein:decreased expression:plasma		 RGD PMID:19556211 PMID:11247331 RGD:5510001, RGD:5510014 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,715...39,864,312 		JBrowse link
G IL10 interleukin 10 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Rheumatoid arthritis, progression of
ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD		 PMID:12847677 PMID:22450443 PMID:25741868 PMID:28492532 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL17A interleukin 17A treatment IMP
IEP		 mRNA:increased expression:synovial (human) RGD PMID:20926833 PMID:22660635 RGD:9068415, RGD:155663483 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16368150 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL19 interleukin 19 IAGP ClinVar Annotator: match by term: Rheumatoid arthritis, progression of
ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO		 ClinVar PMID:12847677 PMID:25741868 PMID:28492532 NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981 		JBrowse link
G IL1A interleukin 1 alpha severity IDA
IEP		 associated with lung disease, interstitial
protein:increased expression:plasma, synovial fluid		 RGD PMID:11192540 PMID:8162643 RGD:4142818, RGD:7794716 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta IEP
EXP		 protein:decreased expression:serum
mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12566094 PMID:17379860 PMID:22450443 PMID:22414257 PMID:22660635 RGD:6482656, RGD:155663483 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IDA
EXP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:7706905 PMID:19192274 PMID:19447938 PMID:10637275 RGD:7174696, RGD:8549810 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 IDA RGD PMID:6421522 RGD:8662948 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL20 interleukin 20 IEP RGD PMID:16947773 RGD:5147395 NCBI chr 1:206,863,565...206,869,223
Ensembl chr 1:206,865,623...206,869,223 		JBrowse link
G IL21R interleukin 21 receptor ISO RGD PMID:19342640 RGD:6892964 NCBI chr16:27,402,174...27,452,042
Ensembl chr16:27,402,174...27,452,042 		JBrowse link
G IL23A interleukin 23 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410 		JBrowse link
G IL23R interleukin 23 receptor susceptibility IAGP DNA:SNP::rs1343151(human) RGD PMID:18647855 RGD:8549596 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:20476861 PMID:23143596 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118 		JBrowse link
G IL3 interleukin 3 IAGP DNA: SNPs: Multiple: gene-gene interaction RGD PMID:20018070 RGD:5686905 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL4R interleukin 4 receptor severity IAGP DNA:SNP: :rs1805010 (human) RGD PMID:24782180 RGD:10402783 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL5 interleukin 5 IEP RGD PMID:22293286 RGD:5687156 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 PMID:22450443 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16729287 PMID:23143596 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer EXP
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:180300		 CTD
MouseDO		 PMID:20453842 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G IRF5 interferon regulatory factor 5 IAGP
IDA
EXP		 ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:15657875 PMID:16642019 PMID:17599733 PMID:18063667 PMID:20453842 More... RGD:40924627, RGD:40924559 NCBI chr 7:128,937,032...128,950,038
Ensembl chr 7:128,937,457...128,950,038 		JBrowse link
G IRF8 interferon regulatory factor 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606 		JBrowse link
G ITGA6 integrin subunit alpha 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 2:172,427,336...172,506,459
Ensembl chr 2:172,234,216...172,506,459 		JBrowse link
G ITPA inosine triphosphatase treatment IAGP DNA:SNP: :94C>A(human) RGD PMID:29441893 RGD:14975307 NCBI chr20:3,204,065...3,227,449
Ensembl chr20:3,208,868...3,223,870 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21510883 RGD:6483024 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KAT2B lysine acetyltransferase 2B IEP mRNA:increased expression:peripheral blood mononuclear cell RGD PMID:36104638 RGD:155791669 NCBI chr 3:20,040,446...20,154,404
Ensembl chr 3:20,040,446...20,154,404 		JBrowse link
G KIF5A kinesin family member 5A susceptibility IAGP
EXP		 DNA:snp:intron:c.1717-152C>G (rs1678542) (human)
CTD Direct Evidence: marker/mechanism
DNA:snps:intron, 3' utr:c.2756-43A>C, c.*776C>T (rs775246, rs775251) (human)		 CTD
RGD		 PMID:23143596 PMID:23378462 PMID:21784728 RGD:12793072, RGD:12793073 NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633 		JBrowse link
G KMT2C lysine methyltransferase 2C treatment ISO RGD PMID:33914205 RGD:151356764 NCBI chr 7:152,134,925...152,436,003
Ensembl chr 7:152,134,922...152,436,644 		JBrowse link
G LCN2 lipocalin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:7554268 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LHX2 LIM homeobox 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 9:124,011,768...124,033,301
Ensembl chr 9:124,001,670...124,033,301 		JBrowse link
G LOC128462409 CRISPRi-FlowFISH-validated IL10 regulatory element GRCh37_chr1:206945468-206946089 IAGP ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:206,772,123...206,772,744 JBrowse link
G LPA lipoprotein(a) IEP protein:increased expression:serum RGD PMID:21523363 RGD:5509910 NCBI chr 6:160,531,482...160,664,275
Ensembl chr 6:160,531,482...160,664,275 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 IEP RGD PMID:17082220 RGD:5508419 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285 		JBrowse link
G LY96 lymphocyte antigen 96 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079 		JBrowse link
G MAB21L2 mab-21 like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 4:150,582,151...150,584,693
Ensembl chr 4:150,582,151...150,584,693 		JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 IEP mRNA:increased expression:cartilage tissue (human) RGD PMID:31472145 RGD:152177908 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,606...65,508,073 		JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475 		JBrowse link
G MBD2 methyl-CpG binding domain protein 2 IEP mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr18:54,151,606...54,224,669
Ensembl chr18:54,151,606...54,224,669 		JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility
no_association		 IAGP DNA:snps:introns:IVS5-140A>G (rs3138355), IVS6-218C>T (rs2005618) (human)
DNA:snps:cds, intron:p.E346K, IVS6-218C>T (rs140693, rs2005618) (human)		 RGD PMID:20676650 PMID:22505706 RGD:9588977, RGD:9588978 NCBI chr 3:129,430,947...129,439,948
Ensembl chr 3:129,430,947...129,440,179 		JBrowse link
G MDK midkine ISO RGD PMID:15146411 RGD:1581200 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837 		JBrowse link
G MGARP mitochondria localized glutamic acid rich protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 4:139,266,165...139,280,225
Ensembl chr 4:139,266,165...139,280,225 		JBrowse link
G MIF macrophage migration inhibitory factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR146A microRNA 146a IEP mRNA:decreased expression:cartilage tissue (human)
mRNA:increased expression:synovial (human)		 RGD PMID:31472145 PMID:22660635 RGD:152177908, RGD:155663483 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450 		JBrowse link
G MIR23B microRNA 23b IEP mRNA, protein:decreased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr 9:95,085,208...95,085,304
Ensembl chr 9:95,085,208...95,085,304 		JBrowse link
G MIR3936HG MIR3936 host gene IAGP ClinVar Annotator: match by term: SLC22A4-related condition ClinVar PMID:19881261 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 5:132,311,276...132,369,916
Ensembl chr 5:132,311,285...132,370,170 		JBrowse link
G MMEL1 membrane metalloendopeptidase like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:2,590,639...2,633,016
Ensembl chr 1:2,590,639...2,633,016 		JBrowse link
G MMP1 matrix metallopeptidase 1 IEP protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP10 matrix metallopeptidase 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MMP12 matrix metallopeptidase 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISS OMIM:180300 MouseDO NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP2 matrix metallopeptidase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 disease_progression IEP protein:increased expression:serum (human) RGD PMID:7639798 PMID:22314025 PMID:11796404 RGD:7207128, RGD:8693673, RGD:7241254 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP8 matrix metallopeptidase 8 IEP protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP RGD PMID:16406300 RGD:1582623 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22450443 PMID:26001728 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 IAGP DNA:missense mutations:cds:multiple (human) RGD PMID:15987486 RGD:5490238 NCBI chr MT:3,307...4,262
Ensembl chr MT:3,307...4,262 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase IAGP
EXP		 DNA:SNP: :677C>T(human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22104130 PMID:23685257 RGD:7387222 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 induced EXP
ISO		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism:M153T (rat)		 CTD
RGD		 PMID:12833524 PMID:28135245 PMID:21275845 RGD:41404729 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism, SNP:cds (rs789181) (human)		 CTD
RGD		 PMID:12833524 PMID:17897462 RGD:41404710 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G NCF4 neutrophil cytosolic factor 4 IAGP DNA:polymorphism, SNP:cds (rs729749) (human) RGD PMID:17897462 RGD:41404710 NCBI chr22:36,861,006...36,878,015
Ensembl chr22:36,860,988...36,878,017 		JBrowse link
G NDUFA4L2 NDUFA4 mitochondrial complex associated like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr12:57,234,903...57,240,762
Ensembl chr12:57,234,903...57,240,715 		JBrowse link
G NFKBIE NFKB inhibitor epsilon EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 6:44,258,166...44,265,551
Ensembl chr 6:44,258,166...44,265,788 		JBrowse link
G NFKBIL1 NFKB inhibitor like 1 susceptibility IAGP
EXP		 DNA:snp:promoter:c.-132T>A (rs2071592) (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Rheumatoid arthritis		 CTD
OMIM
ClinVar
RGD		 PMID:12509789 PMID:12509789 RGD:1331681 NCBI chr 6:31,546,851...31,558,829
Ensembl chr 6:31,546,870...31,558,829 		JBrowse link
G NOTCH4 notch receptor 4 IEP mRNA : increased expression: : cd4+ cells RGD PMID:20132067 RGD:6480790 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067 		JBrowse link
G NPSR1 neuropeptide S receptor 1 IAGP RGD PMID:20179762 RGD:4891930 NCBI chr 7:34,658,218...34,878,332
Ensembl chr 7:34,658,218...34,878,332 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO mRNA:increased expression:paw RGD PMID:18448865 RGD:4892311 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891 		JBrowse link
G OPRM1 opioid receptor mu 1 susceptibility IAGP DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human) RGD PMID:31309790 RGD:401827955 NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867 		JBrowse link
G PADI2 peptidyl arginine deiminase 2 IAGP ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr 1:17,066,761...17,119,451
Ensembl chr 1:17,066,761...17,119,451 		JBrowse link
G PADI4 peptidyl arginine deiminase 4 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Rheumatoid arthritis		 CTD
ClinVar		 PMID:23143596 NCBI chr 1:17,308,197...17,364,004
Ensembl chr 1:17,308,195...17,364,004 		JBrowse link
G PDGFB platelet derived growth factor subunit B IEP RGD PMID:1708827 RGD:6482653 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PGF placental growth factor IEP RGD PMID:19180491 RGD:6483591 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 IEP mRNA:increased expression:cartilage tissue (human) RGD PMID:31472145 RGD:152177908 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PLA2G7 phospholipase A2 group VII IEP RGD PMID:17326817 RGD:6482776 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor IDA RGD PMID:22011479 RGD:6484117 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PLB1 phospholipase B1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24520335 NCBI chr 2:28,496,060...28,644,142
Ensembl chr 2:28,457,145...28,644,142 		JBrowse link
G PLD4 phospholipase D family member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr14:104,924,879...104,937,785
Ensembl chr14:104,924,713...104,937,761 		JBrowse link
G PLEK pleckstrin EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 2:68,365,282...68,397,453
Ensembl chr 2:68,365,282...68,397,453 		JBrowse link
G PON1 paraoxonase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16055108 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G POU3F1 POU class 3 homeobox 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:38,043,829...38,046,793
Ensembl chr 1:38,043,829...38,046,793 		JBrowse link
G PRDM1 PR/SET domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19898481 PMID:20453842 PMID:23143596 PMID:36181686 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G PRKCQ protein kinase C theta EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:23143596 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301 		JBrowse link
G PSG5 pregnancy specific beta-1-glycoprotein 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr19:43,167,743...43,186,536
Ensembl chr19:43,166,256...43,186,536 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15167967 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 IMP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11978490 PMID:19192274 PMID:21905970 RGD:5508313 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr18:12,785,478...12,884,237
Ensembl chr18:12,785,478...12,929,643 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 susceptibility
no_association		 IAGP
EXP		 DNA:snp:cds:p.R620W (rs2476601) (human)
ClinVar Annotator: match by term: Rheumatoid arthritis
ClinVar Annotator: match by term: RHEUMATOID ARTHRITIS, SUSCEPTIBILITY TO
CTD Direct Evidence: marker/mechanism
DNA:SNP::1858C>T (human)
DNA:snp:cds:p.R263Q (rs33996649) (human)		 ClinVar
OMIM
CTD
RGD		 PMID:15004560 PMID:15208781 PMID:15273934 PMID:15580548 PMID:15719322 More... RGD:6484535, RGD:7829746, RGD:6484595 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,759,342 		JBrowse link
G PXK PX domain containing serine/threonine kinase like EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chr 3:58,332,892...58,426,127
Ensembl chr 3:58,332,880...58,426,127 		JBrowse link
G RAB8A RAB8A, member RAS oncogene family EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr19:16,111,889...16,134,234
Ensembl chr19:16,111,889...16,134,234 		JBrowse link
G RAP2A RAP2A, member of RAS oncogene family EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr13:97,434,169...97,469,128
Ensembl chr13:97,434,169...97,469,128 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131 		JBrowse link
G RCAN1 regulator of calcineurin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr21:34,516,442...34,615,113
Ensembl chr21:34,513,142...34,615,113 		JBrowse link
G REL REL proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19503088 PMID:20453842 PMID:23143596 NCBI chr 2:60,881,574...60,931,612
Ensembl chr 2:60,881,491...60,931,612 		JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 5:98,768,632...98,796,494
Ensembl chr 5:98,768,650...98,798,643 		JBrowse link
G RUNX1 RUNX family transcription factor 1 no_association IAGP DNA:SNPs: :rs2242720, rs4816502 (human)
DNA:SNP: :rs2268277 (human)
DNA:SNP:intron:24658G>C (human)		 RGD PMID:20018071 PMID:18087673 PMID:18328148 PMID:16821265 RGD:6482836, RGD:6482840, RGD:6482839, RGD:6482837 NCBI chr21:35,372,507...35,580,764
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX1 RUNX family transcription factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
G RUNX2 RUNX family transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SEMA3C semaphorin 3C IEP protein:increased expression:knee, synovium (human) RGD PMID:15077297 RGD:1580084 NCBI chr 7:80,742,538...80,922,389
Ensembl chr 7:80,742,538...80,922,359 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 severity IAGP
EXP		 DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms, deletion: :823C>T, p.D543N (human)		 CTD
RGD		 PMID:16597321 PMID:12135431 PMID:10719815 RGD:5684967, RGD:5684971 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894 		JBrowse link
G SLC22A4 solute carrier family 22 member 4 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Rheumatoid arthritis
ClinVar Annotator: match by term: SLC22A4-related condition
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:14608356 PMID:19881261 PMID:25741868 PMID:26467025 PMID:28492532 NCBI chr 5:132,294,394...132,344,190
Ensembl chr 5:132,294,394...132,344,190 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859 		JBrowse link
G SMS spermine synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr  X:21,940,709...21,994,837
Ensembl chr  X:21,940,709...21,994,837 		JBrowse link
G SNHG14 small nucleolar RNA host gene 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34529319 NCBI chr15:24,823,608...25,419,462
Ensembl chr15:24,978,583...25,420,336 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 PMID:15292528 PMID:24313545 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPP1 secreted phosphoprotein 1 IDA RGD PMID:15761492 RGD:1581382 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 2:65,307,175...65,432,599
Ensembl chr 2:65,310,851...65,432,637 		JBrowse link
G ST6GALNAC5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 PMID:17568789 NCBI chr 1:76,867,480...77,067,546
Ensembl chr 1:76,867,480...77,067,546 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 IAGP associated with T-cell large granular lymphocyte leukemia RGD PMID:22591296 RGD:6892936 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G STS steroid sulfatase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr  X:7,147,290...7,354,641
Ensembl chr  X:7,147,237...7,804,358 		JBrowse link
G SUPT20H SPT20 homolog, SAGA complex component IAGP ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr13:37,009,312...37,059,688
Ensembl chr13:37,009,312...37,059,713 		JBrowse link
G TAB2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 IEP mRNA, protein:increased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr 6:149,217,926...149,411,607
Ensembl chr 6:149,218,641...149,411,613 		JBrowse link
G TAB3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 IEP mRNA, protein:increased expression:synovial (human) RGD PMID:22660635 RGD:155663483 NCBI chr  X:30,827,442...30,889,254
Ensembl chr  X:30,827,442...30,975,084 		JBrowse link
G TAGAP T cell activation RhoGTPase activating protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr 6:159,034,481...159,044,991
Ensembl chr 6:159,034,468...159,095,823 		JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member IAGP RGD PMID:9645419 RGD:6482275 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 PMID:17379860 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753 		JBrowse link
G THBD thrombomodulin IDA RGD PMID:15700117 RGD:5685020 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TLE3 TLE family member 3, transcriptional corepressor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr15:70,047,790...70,097,917
Ensembl chr15:70,047,790...70,098,176 		JBrowse link
G TLR1 toll like receptor 1 IAGP ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:32594150 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817 		JBrowse link
G TLR2 toll like receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TMPO thymopoietin EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr12:98,515,573...98,550,351
Ensembl chr12:98,515,561...98,550,351 		JBrowse link
G TNF tumor necrosis factor treatment
no_association		 IMP
ISS
IEP
EXP
IAGP		 OMIM:180300
mRNA:increased expression:synovial (human)
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:SNP:promoter:-238G>A, -308G>A (human)
DNA:SNP:promoter:-857C>T (human)		 MouseDO
CTD
RGD		 PMID:2001072 PMID:8391952 PMID:12566094 PMID:22450443 PMID:34459104 More... RGD:10450537, RGD:155663483, RGD:12904065, RGD:12904065 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP2 TNF alpha induced protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr14:103,121,469...103,137,439
Ensembl chr14:103,121,476...103,137,439 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:20453842 PMID:21841782 PMID:23143596 PMID:30224649 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b EXP CTD Direct Evidence: therapeutic CTD PMID:23333834 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment IAGP DNA:SNP:promoter:36G>A (human) RGD PMID:25311255 RGD:12904065 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF14 TNF superfamily member 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr19:6,661,253...6,670,588
Ensembl chr19:6,658,085...6,670,588 		JBrowse link
G TRAF1 TNF receptor associated factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794853 PMID:23143596 NCBI chr 9:120,902,393...120,929,171
Ensembl chr 9:120,902,393...120,929,173 		JBrowse link
G TRAF6 TNF receptor associated factor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842 PMID:23143596 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272 		JBrowse link
G TREM1 triggering receptor expressed on myeloid cells 1 treatment ISO RGD PMID:27049384 RGD:127229930 NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,100...41,286,682 		JBrowse link
G TXNDC5 thioredoxin domain containing 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23326410 NCBI chr 6:7,881,517...7,910,788
Ensembl chr 6:7,881,517...7,910,788 		JBrowse link
G TXNIP thioredoxin interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G TYK2 tyrosine kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 PMID:30224649 NCBI chr19:10,350,533...10,380,572
Ensembl chr19:10,350,528...10,380,608 		JBrowse link
G TYMS thymidylate synthetase treatment IAGP DNA:polymorphism: : RGD PMID:22763757 RGD:11075093 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G TYROBP transmembrane immune signaling adaptor TYROBP treatment ISO RGD PMID:27049384 RGD:127229930 NCBI chr19:35,904,403...35,908,295
Ensembl chr19:35,904,401...35,908,295 		JBrowse link
G VDR vitamin D receptor no_association IAGP DNA:SNP:exon:rs2228570 (human)
DNA:SNP: :rs1544410 (human)		 RGD PMID:21820934 PMID:21820934 RGD:8158077, RGD:8158077 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression IEP
EXP		 protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16368150 PMID:24387171 RGD:8548659 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VIM vimentin IDA RGD PMID:21792832 RGD:6480508 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 ISS OMIM:180300 MouseDO NCBI chr 2:97,713,576...97,756,364
Ensembl chr 2:97,713,576...97,744,327 		JBrowse link
G ZFP36 ZFP36 ring finger protein ISS OMIM:180300 MouseDO NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407 		JBrowse link
adult-onset Still's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HGF hepatocyte growth factor IEP protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G VEGFA vascular endothelial growth factor A IEP protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
Juvenile Pauciarticular Chronic Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphism: :HLA-DRB1*1104, HLA-DRB1*080(human) RGD PMID:7955632 RGD:7365102 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
juvenile rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:132,317,407...132,368,302
Ensembl chr 3:132,317,369...132,368,302 		JBrowse link
G ACRBP acrosin binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:6,638,075...6,647,432
Ensembl chr12:6,638,075...6,647,433 		JBrowse link
G ADCY7 adenylate cyclase 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:50,244,699...50,318,135
Ensembl chr16:50,246,137...50,318,135 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754 		JBrowse link
G ANKRD9 ankyrin repeat domain 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:102,501,767...102,509,776
Ensembl chr14:102,501,767...102,509,799 		JBrowse link
G AOPEP aminopeptidase O (putative) EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:94,726,699...95,150,224
Ensembl chr 9:94,726,604...95,151,793 		JBrowse link
G APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:38,957,609...38,963,184
Ensembl chr22:38,952,741...38,963,184 		JBrowse link
G AQP9 aquaporin 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911 		JBrowse link
G AREG amphiregulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005 		JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:130,052,104...130,443,674
Ensembl chr 8:130,052,104...130,443,674 		JBrowse link
G AVL9 AVL9 cell migration associated EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:32,495,489...32,588,726
Ensembl chr 7:32,495,426...32,588,726 		JBrowse link
G B4GALT5 beta-1,4-galactosyltransferase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr20:49,632,945...49,713,878
Ensembl chr20:49,632,945...49,713,878 		JBrowse link
G BEND2 BEN domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:18,162,931...18,220,886
Ensembl chr  X:18,162,931...18,220,886 		JBrowse link
G BLTP3B bridge-like lipid transfer protein family member 3B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:100,037,072...100,142,874
Ensembl chr12:100,028,455...100,142,874 		JBrowse link
G BTG1 BTG anti-proliferation factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:92,140,278...92,145,846
Ensembl chr12:92,140,278...92,145,846 		JBrowse link
G BTG3 BTG anti-proliferation factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:17,593,653...17,612,901
Ensembl chr21:17,593,653...17,612,945 		JBrowse link
G C2orf88 chromosome 2 open reading frame 88 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:189,879,562...190,203,484
Ensembl chr 2:189,879,609...190,203,484 		JBrowse link
G C8B complement C8 beta chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:7980680 NCBI chr 1:56,929,207...56,966,015
Ensembl chr 1:56,929,207...56,974,383 		JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:27,546,546...27,573,866
Ensembl chr 9:27,535,640...27,573,866 		JBrowse link
G CALD1 caldesmon 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729 		JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:135,808,487...135,907,546
Ensembl chr 9:135,808,487...135,907,546 		JBrowse link
G CCDC122 coiled-coil domain containing 122 IAGP ClinVar Annotator: match by term: JUVENILE ARTHRITIS ClinVar PMID:25741868 NCBI chr13:43,819,018...43,879,740
Ensembl chr13:43,823,909...43,879,740 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association IAGP DNA:polymorphisms: :multiple (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)		 RGD PMID:16775617 PMID:17565662 RGD:1626284, RGD:1626283 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD14 CD14 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD83 CD83 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,140,682 		JBrowse link
G CD8B CD8 subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:86,815,369...86,861,886
Ensembl chr 2:86,815,339...86,861,924 		JBrowse link
G CIITA class II major histocompatibility complex transactivator susceptibility
no_association		 IAGP DNA:polymorphism:exon:1614G>C (human)
DNA:polymorphism:promoter:rs3087456, no association in a German cohort		 RGD PMID:17661914 PMID:16426246 RGD:5491187, RGD:5491189 NCBI chr16:10,866,206...10,943,021
Ensembl chr16:10,866,222...10,943,021 		JBrowse link
G CLU clusterin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CMTM2 CKLF like MARVEL transmembrane domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:66,579,463...66,588,275
Ensembl chr16:66,579,448...66,588,275 		JBrowse link
G CREM cAMP responsive element modulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CRP C-reactive protein IEP protein:increased expression:serum RGD PMID:22885951 RGD:6906884 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CTTN cortactin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 PMID:26387944 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G DAPK1 death associated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DUSP1 dual specificity phosphatase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP2 dual specificity phosphatase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:96,143,169...96,145,440
Ensembl chr 2:96,143,166...96,145,440 		JBrowse link
G DUSP4 dual specificity phosphatase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684 		JBrowse link
G DYSF dysferlin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:71,453,561...71,686,763
Ensembl chr 2:71,453,561...71,686,763 		JBrowse link
G EGF epidermal growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGR1 early growth response 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G ELF2 E74 like ETS transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:139,057,220...139,177,915
Ensembl chr 4:139,028,112...139,177,218 		JBrowse link
G ETNK1 ethanolamine kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:22,625,171...22,690,665
Ensembl chr12:22,625,075...22,690,665 		JBrowse link
G ETV6 ETS variant transcription factor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377 		JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:68,535,116...68,601,367
Ensembl chr17:68,535,113...68,601,367 		JBrowse link
G FAXDC2 fatty acid hydroxylase domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:154,818,492...154,850,603
Ensembl chr 5:154,818,492...154,859,252 		JBrowse link
G FCGR1A Fc gamma receptor Ia EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675 		JBrowse link
G FCHSD2 FCH and double SH3 domains 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:72,836,745...73,142,318
Ensembl chr11:72,836,745...73,142,318 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G FOXP1 forkhead box P1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GMPR guanosine monophosphate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:16,238,587...16,295,549
Ensembl chr 6:16,238,587...16,295,549 		JBrowse link
G GNG11 G protein subunit gamma 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:93,921,735...93,928,610
Ensembl chr 7:93,921,735...93,928,610 		JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:19,723,539...19,724,771
Ensembl chr22:19,723,539...19,724,771 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:18328165 RGD:5490992
G H2AC8 H2A clustered histone 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:26,216,921...26,217,437
Ensembl chr 6:26,216,921...26,218,515 		JBrowse link
G H2BC8 H2B clustered histone 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:26,216,200...26,216,688
Ensembl chr 6:26,216,200...26,216,688 		JBrowse link
G HBEGF heparin binding EGF like growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603 		JBrowse link
G HERPUD2 HERPUD family member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:35,632,659...35,695,135
Ensembl chr 7:35,632,659...35,697,459 		JBrowse link
G HFE homeostatic iron regulator IAGP DNA:missense mutation:cds:p.C282Y (human) RGD PMID:16047841 RGD:8694357 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,226...26,098,343 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IEP
IAGP		 DNA:polymorphism (human) RGD PMID:19811310 PMID:10457895 RGD:5147815, RGD:5147863 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphism (human) RGD PMID:10457895 RGD:5147863 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 IAGP DNA:polymorphism (human) RGD PMID:19908388 PMID:10457895 RGD:5147587, RGD:5147863 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 IEP protein:increased expression:serum,synovial fluid: RGD PMID:8255671 RGD:12910480 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IGF1R insulin like growth factor 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IL1A interleukin 1 alpha IAGP DNA:SNP:promoter:-889C>T (human) RGD PMID:8162643 RGD:7794716 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1RN interleukin 1 receptor antagonist EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 IEP protein:increased expression:mononuclear cell RGD PMID:21859687 RGD:5147870 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL6 interleukin 6 IEP protein:increased expression:serum: RGD PMID:9489833 RGD:7829742 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ITGA2B integrin subunit alpha 2b EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649 		JBrowse link
G ITGB5 integrin subunit beta 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418 		JBrowse link
G JMJD1C jumonji domain containing 1C EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:63,167,225...63,521,890
Ensembl chr10:63,167,221...63,521,850 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KAT6B lysine acetyltransferase 6B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:74,824,936...75,032,624
Ensembl chr10:74,824,927...75,032,624 		JBrowse link
G KCNJ15 potassium inwardly rectifying channel subfamily J member 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:38,229,926...38,307,357
Ensembl chr21:38,155,549...38,307,357 		JBrowse link
G KLF4 KLF transcription factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G LACC1 laccase domain containing 1 IAGP ClinVar Annotator: match by term: JUVENILE ARTHRITIS OMIM
ClinVar		 PMID:25147203 PMID:25220867 PMID:25741868 PMID:27881174 PMID:29717096 More... NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932 		JBrowse link
G LILRA5 leukocyte immunoglobulin like receptor A5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:54,307,070...54,313,166
Ensembl chr19:54,307,070...54,313,166 		JBrowse link
G LPP LIM domain containing preferred translocation partner in lipoma EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:188,153,021...188,890,671
Ensembl chr 3:188,153,284...188,890,671 		JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243 		JBrowse link
G MAFF MAF bZIP transcription factor F EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507 		JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:95,976,598...96,343,195
Ensembl chr11:95,976,598...96,343,195 		JBrowse link
G MAP2 microtubule associated protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MBL2 mannose binding lectin 2 IEP RGD PMID:18334024 RGD:12910845 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MEX3C mex-3 RNA binding family member C EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:51,174,550...51,197,681
Ensembl chr18:51,174,550...51,218,333 		JBrowse link
G MIR22HG MIR22 host gene EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:1,711,504...1,716,210
Ensembl chr17:1,711,447...1,717,174 		JBrowse link
G MS4A4A membrane spanning 4-domains A4A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:60,280,666...60,308,970
Ensembl chr11:60,185,657...60,318,080 		JBrowse link
G MSN moesin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:65,588,377...65,741,931
Ensembl chr  X:65,588,377...65,741,931 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:124,550,784...124,728,473
Ensembl chr 8:124,550,784...124,728,473 		JBrowse link
G MYZAP myocardial zonula adherens protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:57,591,904...57,685,364
Ensembl chr15:57,591,904...57,685,364 		JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:8,413,131...8,474,328
Ensembl chr17:8,413,131...8,490,411 		JBrowse link
G NEAT1 nuclear paraspeckle assembly transcript 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:65,422,798...65,445,540
Ensembl chr11:65,422,278...65,445,540 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891 		JBrowse link
G NRG1 neuregulin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138 		JBrowse link
G OSM oncostatin M EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:30,262,829...30,266,851
Ensembl chr22:30,262,829...30,266,851 		JBrowse link
G PACSIN2 protein kinase C and casein kinase substrate in neurons 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:42,869,766...43,015,149
Ensembl chr22:42,835,412...43,015,149 		JBrowse link
G PCYT1B phosphate cytidylyltransferase 1B, choline EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:24,558,087...24,672,887
Ensembl chr  X:24,558,087...24,672,677 		JBrowse link
G PER1 period circadian regulator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:8,140,472...8,152,404
Ensembl chr17:8,140,467...8,156,506 		JBrowse link
G PGM5 phosphoglucomutase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:68,356,611...68,531,061
Ensembl chr 9:68,328,308...68,531,061 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PLK2 polo like kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139 		JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:146,069,440...146,161,184
Ensembl chr 3:146,035,139...146,163,725 		JBrowse link
G PROS1 protein S EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:93,873,051...93,973,896
Ensembl chr 3:93,873,051...93,980,003 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IAGP DNA: snp : cds : rs2476601 RGD PMID:15934099 RGD:6484550 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G R3HDM2 R3H domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:57,253,764...57,431,141
Ensembl chr12:57,253,762...57,431,043 		JBrowse link
G RASGEF1B RasGEF domain family member 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:81,426,393...81,471,907
Ensembl chr 4:81,426,393...82,044,244 		JBrowse link
G RBM47 RNA binding motif protein 47 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:40,423,280...40,630,852
Ensembl chr 4:40,423,267...40,630,875 		JBrowse link
G RERE arginine-glutamic acid dipeptide repeats EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:8,352,404...8,817,640
Ensembl chr 1:8,352,397...8,848,921 		JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:60,860,860...61,001,967
Ensembl chr10:60,869,438...61,001,440 		JBrowse link
G RNF103 ring finger protein 103 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:86,603,393...86,623,877
Ensembl chr 2:86,603,398...86,623,866 		JBrowse link
G SELP selectin P severity IEP protein:increased expression:plasma RGD PMID:21124648 RGD:6219006 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SH2D2A SH2 domain containing 2A IAGP DNA:polymorphism:promoter RGD PMID:15129233 RGD:2298870 NCBI chr 1:156,806,243...156,816,848
Ensembl chr 1:156,806,240...156,816,848 		JBrowse link
G SH3BGRL2 SH3 domain binding glutamate rich protein like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:79,537,633...79,703,655
Ensembl chr 6:79,537,185...79,703,655 		JBrowse link
G SIK1 salt inducible kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131 		JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:71,320,476...71,741,209
Ensembl chr14:71,320,449...71,741,229 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 IAGP
EXP		 DNA:repeat:promoter (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16597321 PMID:10857800 RGD:5684977 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894 		JBrowse link
G SLC22A16 solute carrier family 22 member 16 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:110,424,687...110,476,613
Ensembl chr 6:110,424,687...110,476,641 		JBrowse link
G SLC26A2 solute carrier family 26 member 2 susceptibility IAGP DNA:SNPs: : RGD PMID:17393463 RGD:13208931 NCBI chr 5:149,960,758...149,987,400
Ensembl chr 5:149,960,758...149,993,455 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007 		JBrowse link
G SMAD3 SMAD family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G STAB1 stabilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:52,495,338...52,524,495
Ensembl chr 3:52,495,338...52,524,495 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STIM1 stromal interaction molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210 		JBrowse link
G TCF7L2 transcription factor 7 like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678 		JBrowse link
G TFDP1 transcription factor Dp-1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:113,584,688...113,641,473
Ensembl chr13:113,584,721...113,641,473 		JBrowse link
G TFPI tissue factor pathway inhibitor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G THBD thrombomodulin IEP protein:increased expression:serum RGD PMID:15209962 RGD:5685023 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G THBS1 thrombospondin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046 		JBrowse link
G TNFAIP8 TNF alpha induced protein 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:119,268,759...119,399,688
Ensembl chr 5:119,268,692...119,399,688 		JBrowse link
G TNFRSF10C TNF receptor superfamily member 10c EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:23,102,921...23,117,445
Ensembl chr 8:23,102,921...23,117,445 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:171,058,414...171,460,408
Ensembl chr 3:171,058,414...171,460,408 		JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:41,149,260...41,155,403
Ensembl chr 6:41,149,337...41,154,347 		JBrowse link
G TTLL5 tubulin tyrosine ligase like 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:75,661,246...75,955,079
Ensembl chr14:75,633,625...75,955,079 		JBrowse link
G TUBB2A tubulin beta 2A class IIa EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544 		JBrowse link
G UBE2E1 ubiquitin conjugating enzyme E2 E1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:23,805,955...23,891,640
Ensembl chr 3:23,805,955...23,891,640 		JBrowse link
G UBE3C ubiquitin protein ligase E3C EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:157,138,926...157,269,370
Ensembl chr 7:157,138,926...157,269,370 		JBrowse link
G WASF3 WASP family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:26,539,139...26,688,948
Ensembl chr13:26,557,683...26,688,948 		JBrowse link
G WWOX WW domain containing oxidoreductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,400...79,212,667 		JBrowse link
G ZFAND3 zinc finger AN1-type containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:37,819,727...38,154,624
Ensembl chr 6:37,819,727...38,154,624 		JBrowse link
G ZFC3H1 zinc finger C3H1-type containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:71,609,599...71,663,848
Ensembl chr12:71,609,599...71,667,725 		JBrowse link
Sjogren's syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIRE autoimmune regulator ISS OMIM:270150 MouseDO NCBI chr21:44,285,876...44,298,648
Ensembl chr21:44,285,838...44,298,648 		JBrowse link
G APOE apolipoprotein E onset IAGP DNA:polymorphism:exon: RGD PMID:15328426 RGD:7495765 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G BDNF brain derived neurotrophic factor severity IEP protein:increased expression:serum: RGD PMID:18830907 RGD:8657019 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BST2 bone marrow stromal cell antigen 2 IEP mRNA, protein:increased expression: labial gland, CD19+ B cell, CD4-CD8-CD19-monocyte: RGD PMID:30249485 RGD:14398821 NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630 		JBrowse link
G C3 complement C3 ISO RGD PMID:17675493 RGD:7401265 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CA1 carbonic anhydrase 1 IDA RGD PMID:12806141 RGD:408425977 NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014 		JBrowse link
G CA2 carbonic anhydrase 2 IDA RGD PMID:15831920 PMID:12806141 RGD:408425973, RGD:408425977 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493 		JBrowse link
G CAST calpastatin IDA associated with Lupus Erythematosus, Systemic RGD PMID:15540513 RGD:5683622 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association IAGP DNA:frameshift mutation: :p.S185_T195del (rs333) (human) RGD PMID:12412204 PMID:23773920 RGD:8551796, RGD:8551818 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 ISS OMIM:270150 MouseDO NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,551,081...40,565,472 		JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:salivary ductal epithelium (human) RGD PMID:12472667 RGD:11520791 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CRP C-reactive protein IEP associated with Arthritis, Rheumatoid;protein:increased expression:serum: RGD PMID:2353152 PMID:16013223 RGD:9491774, RGD:9491835 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 susceptibility IAGP
IEP		 DNA:SNPs,haplotype: :+49A/G (rs231775),(rs3087243)(human)
mRNA:increased expression:salivary gland:		 RGD PMID:16869018 PMID:12528117 RGD:7421506, RGD:7421519 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISS OMIM:270150 MouseDO NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 IAGP associated with Arthritis, Rheumatoid;DNA:polymorphism: :4889A>G (human) RGD PMID:12590982 RGD:5147747 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G DGKQ diacylglycerol kinase theta EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 4:958,887...973,569
Ensembl chr 4:958,887...986,895 		JBrowse link
G E2F1 E2F transcription factor 1 ISS OMIM:270150 MouseDO NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G FAS Fas cell surface death receptor IEP
ISS
ISO		 protein:increased expression:serum (human)
OMIM:270150
protein:decreased expression:lacrimal gland, lymphocyte (mouse)		 MouseDO
RGD		 PMID:9890678 PMID:9870874 PMID:11157873 RGD:8662410, RGD:8662451, RGD:8662436 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FCGR2A Fc gamma receptor IIa EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 1:161,505,457...161,524,048
Ensembl chr 1:161,505,430...161,524,013 		JBrowse link
G GDNF glial cell derived neurotrophic factor IEP RGD PMID:9853108 RGD:6218983 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GTF2I general transcription factor IIi EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097066 NCBI chr 7:74,657,718...74,760,692
Ensembl chr 7:74,650,231...74,760,692 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP DNA:polymorphism:cds:HLA-DQA1*0101 (human)
DNA:polymorphisms::HLA-DQA1*0501,LA-DQA1*0301/2;		 RGD PMID:11555411 PMID:21315052 RGD:5147809, RGD:7421543 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP DNA:polymorphisms:cds:HLA-DQB1*0201 (human)
associated with Chronic Hepatitis C;DNA:polymorphism:cds:HLA-DQB1*02 (human)
DNA:polymorphisms, haplotypes:cds:HLA-DQB1*0201, HLA-DQB1*0401, HLA-DQB1*0601 (human)		 RGD PMID:21315052 PMID:17489060 PMID:8468491 RGD:7421543, RGD:36174022, RGD:7483566 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphism:cds:HLA-DRB1*0301 (human) RGD PMID:11555411 RGD:5147809 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO RGD PMID:24941846 RGD:10450595 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 IDA RGD PMID:19264855 RGD:10054311 NCBI chr 5:179,614,178...179,634,784
Ensembl chr 5:179,614,178...179,634,784 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment IEP
ISO		 protein:increased expression:salivary gland
protein:increased expression:plasma		 RGD PMID:11359451 PMID:21589878 PMID:15037117 RGD:8158122, RGD:8547705, RGD:8547696 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID3 inhibitor of DNA binding 3 ISS OMIM:270150 MouseDO NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501 		JBrowse link
G IFNG interferon gamma ISO
IEP		 RGD PMID:15584966 PMID:28421993 RGD:8142390, RGD:14975117 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL10 interleukin 10 IAGP RGD PMID:12233881 RGD:1580479 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12A interleukin 12A EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL17A interleukin 17A ISO RGD PMID:21182786 RGD:8696035 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL18 interleukin 18 IEP protein:increased expression:saliva RGD PMID:23906036 RGD:8655918 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IAGP
IEP		 DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
protein:increased expression:conjunctiva (human)		 RGD PMID:9646842 PMID:11527941 RGD:8549786, RGD:8549807 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 ISS OMIM:270150 MouseDO NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL23R interleukin 23 receptor IEP protein:increased expression:minor salivary gland: RGD PMID:22262980 RGD:8549566 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISS OMIM:270150 MouseDO NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G IL4 interleukin 4 ISS OMIM:270150 MouseDO NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 severity IEP
IAGP		 protein:increased expression:plasma:
DNA:polymorphims:promoter:-174G>C(human)		 RGD PMID:11426023 PMID:11426023 RGD:7829718, RGD:7829718 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IRAK1BP1 interleukin 1 receptor associated kinase 1 binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 6:78,867,551...78,979,411
Ensembl chr 6:78,867,551...78,946,440 		JBrowse link
G ITSN2 intersectin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 2:24,202,864...24,361,368
Ensembl chr 2:24,202,864...24,360,536 		JBrowse link
G LTA lymphotoxin alpha no_association
susceptibility		 ISO
IAGP
IEP		 DNA:SNPs: :multiple (human)
DNA:SNP, haplotype:intron: (rs909253) (human)
protein:increased expression:saliva, serum		 RGD PMID:20952683 PMID:22294627 PMID:22294627 PMID:20952683 RGD:8548776, RGD:8548787, RGD:8548787, RGD:8548776 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G MAP3K14 mitogen-activated protein kinase kinase kinase 14 ISS OMIM:270150 MouseDO NCBI chr17:45,263,119...45,317,020
Ensembl chr17:45,263,119...45,317,029 		JBrowse link
G MMP3 matrix metallopeptidase 3 IEP RGD PMID:19332626 RGD:8693671 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP
IDA		 protein:increased activity:saliva RGD PMID:15316122 PMID:9923658 RGD:8547814, RGD:8547858 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MUC16 mucin 16, cell surface associated IEP mRNA, protein:increased expression:conjunctival epithelial cell, tear RGD PMID:19122828 RGD:7364772 NCBI chr19:8,848,844...9,065,751
Ensembl chr19:8,848,844...9,010,390 		JBrowse link
G MUC19 mucin 19, oligomeric (gene/pseudogene) IEP
ISS		 mRNA:decreased expression:conjunctival epithelial cell
OMIM:270150		 MouseDO
RGD		 PMID:18184611 RGD:7364736 NCBI chr12:40,393,394...40,570,757
Ensembl chr12:40,393,395...40,570,832 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming IEP mRNA:decreased expression:conjunctival epithelial cell RGD PMID:18184611 RGD:7364736 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28135245 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NEFL neurofilament light chain IEP protein:increased expression:CSF (human) RGD PMID:32423153 RGD:127284890 NCBI chr 8:24,950,955...24,956,612
Ensembl chr 8:24,950,955...24,956,721 		JBrowse link
G NFKBIA NFKB inhibitor alpha ISS
ISO		 OMIM:270150 MouseDO
RGD		 PMID:20696914 RGD:126908016 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G PHIP pleckstrin homology domain interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 6:78,934,419...79,078,254
Ensembl chr 6:78,934,419...79,078,287 		JBrowse link
G PON1 paraoxonase 1 IEP protein:decreased activity:serum (human) RGD PMID:20497955 RGD:8547550 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G PRDM1 PR/SET domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 no_association IAGP DNA:snp:cds:c.1858C>T (human) RGD PMID:16163373 PMID:15933742 RGD:11534998, RGD:11534999 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753 		JBrowse link
G PTTG1 PTTG1 regulator of sister chromatid separation, securin EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 5:160,421,855...160,428,744
Ensembl chr 5:160,421,855...160,428,739 		JBrowse link
G REG1A regenerating family member 1 alpha IEP protein:increased expression:minor salivary gland, salivary ductal epithelium (human) RGD PMID:19016805 RGD:9850137 NCBI chr 2:79,120,488...79,123,409
Ensembl chr 2:79,120,362...79,123,409 		JBrowse link
G RORC RAR related orphan receptor C ISS OMIM:270150 MouseDO NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845 		JBrowse link
G SATB1 SATB homeobox 1 ISS OMIM:270150 MouseDO NCBI chr 3:18,345,377...18,445,592
Ensembl chr 3:18,345,377...18,445,621 		JBrowse link
G SELP selectin P IEP protein:increased expression:plasma RGD PMID:19832990 RGD:6478702 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G ST14 ST14 transmembrane serine protease matriptase ISS OMIM:270150 MouseDO NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 susceptibility
no_association		 IAGP
EXP		 DNA:SNP:intron: (rs7582694) (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:intron: (rs7574865) (human)		 CTD
RGD		 PMID:24097066 PMID:24097067 PMID:20535138 PMID:20360187 PMID:18273036 RGD:8661690, RGD:8661709, RGD:8661708 NCBI chr 2:191,029,576...191,151,596
Ensembl chr 2:191,029,576...191,178,435 		JBrowse link
G TGFB1 transforming growth factor beta 1 severity ISO
ISS		 OMIM:270150 MouseDO
RGD		 PMID:9358754 PMID:7554451 RGD:7394829, RGD:7394845 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G THBS1 thrombospondin 1 ISS OMIM:270150 MouseDO NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G TNF tumor necrosis factor treatment IAGP
ISO		 DNA:polymorphism: :-1031T>C(human) RGD PMID:22703762 PMID:24941846 RGD:7394766, RGD:10450595 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097066 PMID:24097067 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314 		JBrowse link
G TNFSF13B TNF superfamily member 13b ISS OMIM:270150 MouseDO NCBI chr13:108,269,629...108,308,484
Ensembl chr13:108,251,240...108,308,484 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24097067 NCBI chr 5:151,029,943...151,087,685
Ensembl chr 5:151,029,945...151,093,577 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 ISS OMIM:270150 MouseDO NCBI chr 6:111,555,381...111,605,878
Ensembl chr 6:111,555,381...111,606,906 		JBrowse link
G VIM vimentin IDA RGD PMID:6352937 RGD:6480477 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:22059987 RGD:5685375 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
Sjögren-Mikulicz Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion: : RGD PMID:10616008 RGD:5491001 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
Systemic Juvenile Rheumatoid Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDO1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:26914138 RGD:11529541 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IL6 interleukin 6 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor treatment IMP RGD PMID:18358927 RGD:10402823 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G MIF macrophage migration inhibitory factor susceptibility IAGP
EXP		 CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97386
    disease of anatomical entity 91015
      musculoskeletal system disease 20999
        connective tissue disease 15993
          rheumatic disease 4352
            rheumatoid arthritis 3386
              Caplan's syndrome 0
              Felty's syndrome 0
              Rheumatoid Nodule 0
              Rheumatoid Vasculitis 0
              Sjogren's syndrome + 127
              Sjögren-Mikulicz Syndrome 1
              adult-onset Still's disease 3
              juvenile rheumatoid arthritis + 330
              palindromic rheumatism 0
Path 2
Term Annotations click to browse term
  disease 97386
    disease of anatomical entity 91015
      Skin and Connective Tissue Diseases 23010
        connective tissue disease 15993
          bone disease 12631
            bone inflammation disease 6250
              arthropathy 6224
                arthritis 5070
                  rheumatoid arthritis 3386
                    Caplan's syndrome 0
                    Felty's syndrome 0
                    Rheumatoid Nodule 0
                    Rheumatoid Vasculitis 0
                    Sjogren's syndrome + 127
                    Sjögren-Mikulicz Syndrome 1
                    adult-onset Still's disease 3
                    juvenile rheumatoid arthritis + 330
                    palindromic rheumatism 0
paths to the root