NPSR1 (neuropeptide S receptor 1) - Rat Genome Database

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Gene: NPSR1 (neuropeptide S receptor 1) Homo sapiens
Analyze
Symbol: NPSR1
Name: neuropeptide S receptor 1
RGD ID: 1347629
HGNC Page HGNC:23631
Description: Enables neuropeptide receptor activity. Involved in neuropeptide signaling pathway and positive regulation of release of sequestered calcium ion into cytosol. Located in cytoplasm and plasma membrane. Implicated in asthma; inflammatory bowel disease; newborn respiratory distress syndrome; and rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ASRT2; G protein-coupled receptor 154; G protein-coupled receptor for asthma susceptibility; G-protein coupled receptor 154; G-protein coupled receptor for asthma susceptibility; G-protein coupled receptor PGR14; GPR154; GPRA; neuropeptide S receptor; NPSR; PGR14; vasopressin receptor-related receptor 1; VRR1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38734,658,218 - 34,878,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl734,658,218 - 34,878,332 (+)EnsemblGRCh38hg38GRCh38
GRCh37734,697,830 - 34,917,944 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36734,664,422 - 34,884,469 (+)NCBINCBI36Build 36hg18NCBI36
Build 34734,471,136 - 34,691,184NCBI
Celera734,678,763 - 34,899,690 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef734,579,047 - 34,799,739 (+)NCBIHuRef
CHM1_1734,697,921 - 34,917,510 (+)NCBICHM1_1
T2T-CHM13v2.0734,798,021 - 35,019,005 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2734,742,034 - 34,962,952 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA,IEA)
membrane  (IEA)
plasma membrane  (IBA,IDA,IEA,TAS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms. Bruce S, etal., J Med Genet. 2009 Mar;46(3):159-67. Epub 2008 Feb 19.
2. Neuropeptide s receptor 1 gene polymorphism is associated with susceptibility to inflammatory bowel disease. D'Amato M, etal., Gastroenterology. 2007 Sep;133(3):808-17. Epub 2007 Jun 20.
3. Analysis of neuropeptide S receptor gene (NPSR1) polymorphism in rheumatoid arthritis. D'Amato M, etal., PLoS One. 2010 Feb 22;5(2):e9315.
4. The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S. Fedeli A, etal., Eur J Neurosci. 2009 Oct;30(8):1594-602. doi: 10.1111/j.1460-9568.2009.06948.x. Epub 2009 Oct 12.
5. Morphine dependence is associated with changes in neuropeptide S receptor expression and function in rat brain. Ghazal P, etal., Peptides. 2013 Aug;46:6-12. doi: 10.1016/j.peptides.2013.05.001. Epub 2013 May 16.
6. Comprehensive testing of positionally cloned asthma genes in two populations. Hersh CP, etal., Am J Respir Crit Care Med. 2007 Nov 1;176(9):849-57. Epub 2007 Aug 16.
7. Characterization of a common susceptibility locus for asthma-related traits. Laitinen T, etal., Science. 2004 Apr 9;304(5668):300-4.
8. Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala. Medina G, etal., Mol Pain. 2014 May 29;10:32. doi: 10.1186/1744-8069-10-32.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. G protein-coupled receptor for asthma susceptibility associates with respiratory distress syndrome. Pulkkinen V, etal., Ann Med. 2006;38(5):357-66.
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Neuropeptide S receptor gene expression in alcohol withdrawal and protracted abstinence in postdependent rats. Ruggeri B, etal., Alcohol Clin Exp Res. 2010 Jan;34(1):90-7. doi: 10.1111/j.1530-0277.2009.01070.x. Epub 2009 Oct 23.
14. Antagonism of the neuropeptide S receptor with RTI-118 decreases cocaine self-administration and cocaine-seeking behavior in rats. Schmoutz CD, etal., Pharmacol Biochem Behav. 2012 Dec;103(2):332-7. doi: 10.1016/j.pbb.2012.09.003. Epub 2012 Sep 12.
Additional References at PubMed
PMID:12036966   PMID:12477932   PMID:12679517   PMID:12690205   PMID:14702039   PMID:14757815   PMID:15312648   PMID:15710598   PMID:15741670   PMID:15764725   PMID:15777626   PMID:15941840  
PMID:15947423   PMID:15990798   PMID:16098057   PMID:16522461   PMID:16790440   PMID:16829631   PMID:16926187   PMID:17210045   PMID:17285544   PMID:17669576   PMID:17703412   PMID:18029348  
PMID:18305139   PMID:18340359   PMID:18588753   PMID:19247692   PMID:19258923   PMID:19264973   PMID:19325992   PMID:19614867   PMID:19624525   PMID:19732772   PMID:19824051   PMID:19874863  
PMID:19913121   PMID:19951440   PMID:19996348   PMID:20379614   PMID:20503287   PMID:20603625   PMID:20628086   PMID:20628342   PMID:20701904   PMID:20705147   PMID:21525857   PMID:21707994  
PMID:21873635   PMID:22078257   PMID:22216302   PMID:22404660   PMID:22479518   PMID:22548958   PMID:23103692   PMID:23142110   PMID:23319044   PMID:23325374   PMID:23372674   PMID:23382691  
PMID:23466585   PMID:23565190   PMID:23680103   PMID:23911665   PMID:24239856   PMID:24331455   PMID:24439655   PMID:24754478   PMID:24800784   PMID:24896296   PMID:24915894   PMID:25091462  
PMID:25744621   PMID:25842293   PMID:25971599   PMID:26235955   PMID:26503268   PMID:26865629   PMID:27145233   PMID:27176146   PMID:27883964   PMID:28298427   PMID:30190127   PMID:30242809  
PMID:30472966   PMID:30616163   PMID:30695550   PMID:30927345   PMID:31132388   PMID:31291233   PMID:31734525   PMID:32846769   PMID:33289016   PMID:33332443   PMID:33902914   PMID:33961781  
PMID:34433639   PMID:39332092  


Genomics

Comparative Map Data
NPSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38734,658,218 - 34,878,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl734,658,218 - 34,878,332 (+)EnsemblGRCh38hg38GRCh38
GRCh37734,697,830 - 34,917,944 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36734,664,422 - 34,884,469 (+)NCBINCBI36Build 36hg18NCBI36
Build 34734,471,136 - 34,691,184NCBI
Celera734,678,763 - 34,899,690 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef734,579,047 - 34,799,739 (+)NCBIHuRef
CHM1_1734,697,921 - 34,917,510 (+)NCBICHM1_1
T2T-CHM13v2.0734,798,021 - 35,019,005 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2734,742,034 - 34,962,952 (+)NCBI
Npsr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39924,009,212 - 24,229,151 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl924,009,292 - 24,227,694 (+)EnsemblGRCm39 Ensembl
GRCm38924,097,912 - 24,317,590 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl924,097,996 - 24,316,398 (+)EnsemblGRCm38mm10GRCm38
MGSCv37923,902,462 - 24,120,842 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36923,848,425 - 24,066,805 (+)NCBIMGSCv36mm8
Celera921,355,713 - 21,573,552 (+)NCBICelera
Cytogenetic Map9A3- A4NCBI
cM Map99.99NCBI
Npsr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8830,882,830 - 31,107,425 (+)NCBIGRCr8
mRatBN7.2822,606,946 - 22,831,558 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl822,606,946 - 22,831,558 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx826,641,001 - 26,865,608 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0824,938,241 - 25,162,852 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0822,837,781 - 23,062,363 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0825,246,174 - 25,483,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl825,246,292 - 25,482,647 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0825,328,131 - 25,514,199 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4823,736,081 - 23,970,242 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera824,184,221 - 24,410,253 (+)NCBICelera
Cytogenetic Map8q13NCBI
Npsr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555601,069,651 - 1,243,111 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555601,069,651 - 1,243,111 (-)NCBIChiLan1.0ChiLan1.0
NPSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2639,471,925 - 39,692,384 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1787,796,660 - 88,017,106 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0735,274,102 - 35,494,389 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1735,663,335 - 35,883,988 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl735,663,335 - 35,883,988 (+)Ensemblpanpan1.1panPan2
NPSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11446,465,169 - 46,610,256 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1446,466,544 - 46,609,477 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1445,908,550 - 46,051,177 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01446,406,554 - 46,549,450 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1446,406,661 - 46,549,459 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11446,514,493 - 46,657,229 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01446,191,033 - 46,333,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01446,564,692 - 46,707,288 (+)NCBIUU_Cfam_GSD_1.0
Npsr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511891,141,108 - 91,331,221 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647810,352,741 - 10,544,102 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647810,352,894 - 10,542,949 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPSR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1838,942,487 - 39,085,754 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11838,942,499 - 39,212,791 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21842,772,920 - 42,892,071 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12123,558,313 - 23,784,475 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604279,478,183 - 79,684,440 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in NPSR1
21 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_207172.2(NPSR1):c.320A>T (p.Asn107Ile) single nucleotide variant Asthma-related traits, susceptibility to, 2 [RCV000002276] Chr7:34778501 [GRCh38]
Chr7:34818113 [GRCh37]
Chr7:7p14.3		 risk factor
NM_207173.1(NPSR1):c.1026-8271T>C single nucleotide variant Lung cancer [RCV000106005] Chr7:34869805 [GRCh38]
Chr7:34909417 [GRCh37]
Chr7:7p14.3		 uncertain significance
GRCh38/hg38 7p22.3-14.1(chr7:54185-41875885)x3 copy number gain See cases [RCV000051159] Chr7:54185..41875885 [GRCh38]
Chr7:54185..41915483 [GRCh37]
Chr7:149268..41882008 [NCBI36]
Chr7:7p22.3-14.1		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p22.3-14.2(chr7:54185-37089712)x3 copy number gain See cases [RCV000053530] Chr7:54185..37089712 [GRCh38]
Chr7:54185..37129317 [GRCh37]
Chr7:149268..37095842 [NCBI36]
Chr7:7p22.3-14.2		 pathogenic
GRCh38/hg38 7p14.3-q11.21(chr7:33328312-62377476)x3 copy number gain See cases [RCV000053532] Chr7:33328312..62377476 [GRCh38]
Chr7:33367924..61831899 [GRCh37]
Chr7:33334449..61469334 [NCBI36]
Chr7:7p14.3-q11.21		 pathogenic
NM_207173.1(NPSR1):c.30C>T (p.Phe10=) single nucleotide variant Malignant melanoma [RCV000067856] Chr7:34658442 [GRCh38]
Chr7:34698054 [GRCh37]
Chr7:34664579 [NCBI36]
Chr7:7p14.3		 not provided
NM_207173.1(NPSR1):c.31G>C (p.Asp11His) single nucleotide variant Malignant melanoma [RCV000067857] Chr7:34658443 [GRCh38]
Chr7:34698055 [GRCh37]
Chr7:34664580 [NCBI36]
Chr7:7p14.3		 not provided
NM_207173.1(NPSR1):c.128C>T (p.Ser43Phe) single nucleotide variant Malignant melanoma [RCV000067858] Chr7:34658540 [GRCh38]
Chr7:34698152 [GRCh37]
Chr7:34664677 [NCBI36]
Chr7:7p14.3		 not provided
NM_207173.1(NPSR1):c.450C>T (p.Ile150=) single nucleotide variant Malignant melanoma [RCV000067859] Chr7:34811835 [GRCh38]
Chr7:34851447 [GRCh37]
Chr7:34817972 [NCBI36]
Chr7:7p14.3		 not provided
NM_207173.1(NPSR1):c.82G>A (p.Glu28Lys) single nucleotide variant Malignant melanoma [RCV000061634] Chr7:34658494 [GRCh38]
Chr7:34698106 [GRCh37]
Chr7:34664631 [NCBI36]
Chr7:7p14.3		 not provided
NM_207172.1(NPSR1):c.1026G>A (p.Arg342=) single nucleotide variant Malignant melanoma [RCV000061635] Chr7:34849565 [GRCh38]
Chr7:34889177 [GRCh37]
Chr7:34855702 [NCBI36]
Chr7:7p14.3		 not provided
NM_207173.1(NPSR1):c.1032C>T (p.Ile344=) single nucleotide variant Malignant melanoma [RCV000061636] Chr7:34878082 [GRCh38]
Chr7:34917694 [GRCh37]
Chr7:34884219 [NCBI36]
Chr7:7p14.3		 not provided
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p14.3-14.1(chr7:32678391-41044983)x1 copy number loss See cases [RCV000140283] Chr7:32678391..41044983 [GRCh38]
Chr7:32718003..41084581 [GRCh37]
Chr7:32684528..41051106 [NCBI36]
Chr7:7p14.3-14.1		 pathogenic
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34		 pathogenic
GRCh37/hg19 7p21.3-14.2(chr7:11562624-36395416)x3 copy number gain See cases [RCV000446478] Chr7:11562624..36395416 [GRCh37]
Chr7:7p21.3-14.2		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p14.3-13(chr7:32911003-44576005)x1 copy number loss See cases [RCV000446955] Chr7:32911003..44576005 [GRCh37]
Chr7:7p14.3-13		 pathogenic
GRCh37/hg19 7p21.3-12.1(chr7:11048840-52863626)x3 copy number gain See cases [RCV000512091] Chr7:11048840..52863626 [GRCh37]
Chr7:7p21.3-12.1		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p14.3-13(chr7:30463886-43470805)x3 copy number gain not provided [RCV000682909] Chr7:30463886..43470805 [GRCh37]
Chr7:7p14.3-13		 pathogenic
GRCh37/hg19 7p14.3(chr7:34086180-34959828)x1 copy number loss not provided [RCV000682871] Chr7:34086180..34959828 [GRCh37]
Chr7:7p14.3		 uncertain significance
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Childhood apraxia of speech [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p14.3(chr7:34896123-34912086)x1 copy number loss not provided [RCV000746615] Chr7:34896123..34912086 [GRCh37]
Chr7:7p14.3		 benign
GRCh37/hg19 7p14.3(chr7:34896123-34917263)x1 copy number loss not provided [RCV000746616] Chr7:34896123..34917263 [GRCh37]
Chr7:7p14.3		 benign
NM_207172.2(NPSR1):c.427A>G (p.Ser143Gly) single nucleotide variant not provided [RCV000948764] Chr7:34811812 [GRCh38]
Chr7:34851424 [GRCh37]
Chr7:7p14.3		 benign
NM_207172.2(NPSR1):c.148-7C>G single nucleotide variant not provided [RCV000969033] Chr7:34684545 [GRCh38]
Chr7:34724157 [GRCh37]
Chr7:7p14.3		 benign
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p14.3-14.2(chr7:34432783-35083191)x1 copy number loss not provided [RCV001005932] Chr7:34432783..35083191 [GRCh37]
Chr7:7p14.3-14.2		 uncertain significance
GRCh37/hg19 7p14.3-14.2(chr7:34920075-35212065) copy number gain Aortic valve disease 1 [RCV000770941] Chr7:34920075..35212065 [GRCh37]
Chr7:7p14.3-14.2		 uncertain significance
GRCh37/hg19 7p14.3-14.2(chr7:34859227-35374178)x1 copy number loss not provided [RCV001005933] Chr7:34859227..35374178 [GRCh37]
Chr7:7p14.3-14.2		 uncertain significance
NM_207172.2(NPSR1):c.345G>A (p.Thr115=) single nucleotide variant not provided [RCV000975148] Chr7:34778526 [GRCh38]
Chr7:34818138 [GRCh37]
Chr7:7p14.3		 benign
Single allele complex Ring chromosome 7 [RCV002280646] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p21.3-14.2(chr7:10745750-35305167) copy number gain not specified [RCV002053668] Chr7:10745750..35305167 [GRCh37]
Chr7:7p21.3-14.2		 likely pathogenic
GRCh37/hg19 7p15.2-14.1(chr7:27507832-39072473) copy number gain not specified [RCV002053677] Chr7:27507832..39072473 [GRCh37]
Chr7:7p15.2-14.1		 likely pathogenic
NC_000007.13:g.(?_33217070)_(34888295_?)dup duplication not provided [RCV003123051] Chr7:33217070..34888295 [GRCh37]
Chr7:7p14.3		 uncertain significance
GRCh37/hg19 7p22.3-q36.3(chr7:56604613-96692931)x1 copy number loss See cases [RCV002287832] Chr7:56604613..96692931 [GRCh37]
Chr7:7p22.3-q36.3		 uncertain significance
NM_207172.2(NPSR1):c.850A>G (p.Ile284Val) single nucleotide variant not specified [RCV004224352] Chr7:34848488 [GRCh38]
Chr7:34888100 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_207172.2(NPSR1):c.32A>G (p.Asp11Gly) single nucleotide variant not specified [RCV004214464] Chr7:34658444 [GRCh38]
Chr7:34698056 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_207172.2(NPSR1):c.794T>C (p.Ile265Thr) single nucleotide variant not specified [RCV004225616] Chr7:34844932 [GRCh38]
Chr7:34884544 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_207172.2(NPSR1):c.73G>A (p.Ala25Thr) single nucleotide variant not specified [RCV004143817] Chr7:34658485 [GRCh38]
Chr7:34698097 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_207172.2(NPSR1):c.652G>A (p.Val218Met) single nucleotide variant not specified [RCV004115280] Chr7:34827574 [GRCh38]
Chr7:34867186 [GRCh37]
Chr7:7p14.3		 uncertain significance
NM_207172.2(NPSR1):c.342C>T (p.Phe114=) single nucleotide variant not provided [RCV003436711] Chr7:34778523 [GRCh38]
Chr7:34818135 [GRCh37]
Chr7:7p14.3		 likely benign
GRCh37/hg19 7p14.3-14.1(chr7:33478398-39686397)x1 copy number loss not specified [RCV003986710] Chr7:33478398..39686397 [GRCh37]
Chr7:7p14.3-14.1		 likely pathogenic
NM_207172.2(NPSR1):c.658T>C (p.Phe220Leu) single nucleotide variant not specified [RCV004650328] Chr7:34827580 [GRCh38]
Chr7:34867192 [GRCh37]
Chr7:7p14.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2342
Count of miRNA genes:764
Interacting mature miRNAs:891
Transcripts:ENST00000359791, ENST00000360581, ENST00000381539, ENST00000381542, ENST00000381544, ENST00000381553, ENST00000396095, ENST00000465305, ENST00000531252
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407208709GWAS857685_Hamino acid measurement QTL GWAS857685 (human)0.000008amino acid measurement73471457134714572Human
406901477GWAS550453_Heducational attainment QTL GWAS550453 (human)1e-08educational attainment73486969134869692Human
407073637GWAS722613_Hanti-thyroglobulin antibody measurement QTL GWAS722613 (human)0.0000003anti-thyroglobulin antibody measurement73469659034696591Human
407020132GWAS669108_Hbone density QTL GWAS669108 (human)1e-13bone mineral mass (VT:0005007)bone mineral density (CMO:0001226)73476499034764991Human
406901478GWAS550454_Heducational attainment QTL GWAS550454 (human)0.000002educational attainment73487616334876164Human
406906073GWAS555049_Htrait in response to apixaban QTL GWAS555049 (human)2e-09trait in response to apixaban73466616034666161Human
1559132SAPOB3_HSerum apolipoprotein B level QTL 3 (human)20.4Apolipoprotein levelapolipoprotein B73289107458891074Human
407242589GWAS891565_Hcarotid artery intima media thickness QTL GWAS891565 (human)0.000006carotid artery intima media thickness73468166134681662Human
407103208GWAS752184_HFEV/FVC ratio, response to bronchodilator QTL GWAS752184 (human)0.000003FEV/FVC ratio, response to bronchodilatorforced expiratory volume to forced vital capacity ratio (CMO:0000241)73485980234859803Human
2289453BW297_HBody weight QTL 297 (human)3.83Body weightbody mass index72334946449349464Human

Markers in Region
D7S497  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,764,670 - 34,764,772UniSTSGRCh37
Build 36734,731,195 - 34,731,297RGDNCBI36
Celera734,745,544 - 34,745,646RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,645,619 - 34,645,721UniSTS
CRA_TCAGchr7v2734,808,794 - 34,808,896UniSTS
Marshfield Genetic Map753.5RGD
Marshfield Genetic Map753.5UniSTS
Genethon Genetic Map754.8UniSTS
deCODE Assembly Map754.43UniSTS
Whitehead-YAC Contig Map7 UniSTS
G42097  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,870,844 - 34,871,157UniSTSGRCh37
Build 36734,837,369 - 34,837,682RGDNCBI36
Celera734,852,592 - 34,852,905RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,752,646 - 34,752,959UniSTS
CRA_TCAGchr7v2734,915,853 - 34,916,166UniSTS
G42099  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,702,632 - 34,702,778UniSTSGRCh37
Build 36734,669,157 - 34,669,303RGDNCBI36
Celera734,683,498 - 34,683,656RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,583,782 - 34,583,946UniSTS
CRA_TCAGchr7v2734,746,769 - 34,746,915UniSTS
G42100  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,763,090 - 34,763,237UniSTSGRCh37
Build 36734,729,615 - 34,729,762RGDNCBI36
Celera734,743,964 - 34,744,111RGD
Cytogenetic Map7p14.3UniSTS
CRA_TCAGchr7v2734,807,214 - 34,807,361UniSTS
G42102  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,745,153 - 34,745,295UniSTSGRCh37
Build 36734,711,678 - 34,711,820RGDNCBI36
Celera734,726,027 - 34,726,169RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,626,321 - 34,626,463UniSTS
CRA_TCAGchr7v2734,789,276 - 34,789,418UniSTS
SHGC-83741  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,722,348 - 34,722,643UniSTSGRCh37
Build 36734,688,873 - 34,689,168RGDNCBI36
Celera734,703,220 - 34,703,515RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,603,535 - 34,603,830UniSTS
CRA_TCAGchr7v2734,766,479 - 34,766,774UniSTS
TNG Radiation Hybrid Map716376.0UniSTS
GDB:3755035  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,864,451 - 34,864,562UniSTSGRCh37
Build 36734,830,976 - 34,831,087RGDNCBI36
Celera734,846,199 - 34,846,310RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,746,253 - 34,746,364UniSTS
CRA_TCAGchr7v2734,909,460 - 34,909,571UniSTS
WI-21900  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37126,640,994 - 6,641,093UniSTSGRCh37
GRCh37734,789,632 - 34,789,732UniSTSGRCh37
Build 36734,756,157 - 34,756,257RGDNCBI36
Celera128,257,855 - 8,257,954UniSTS
Celera734,770,506 - 34,770,606RGD
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map11q12.2-q13.1UniSTS
Cytogenetic Map7p14.3UniSTS
HuRef126,495,238 - 6,495,337UniSTS
HuRef734,670,580 - 34,670,680UniSTS
CRA_TCAGchr7v2734,833,757 - 34,833,857UniSTS
GeneMap99-GB4 RH Map1242.78UniSTS
Whitehead-RH Map1273.2UniSTS
D7S3241  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,885,299 - 34,885,579UniSTSGRCh37
Build 36734,851,824 - 34,852,104RGDNCBI36
Celera734,867,047 - 34,867,327RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,767,101 - 34,767,381UniSTS
CRA_TCAGchr7v2734,930,308 - 34,930,588UniSTS
G16032  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,785,639 - 34,785,738UniSTSGRCh37
Build 36734,752,164 - 34,752,263RGDNCBI36
Celera734,766,513 - 34,766,612RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,666,588 - 34,666,687UniSTS
CRA_TCAGchr7v2734,829,764 - 34,829,863UniSTS
SHGC-56032  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,723,155 - 34,723,304UniSTSGRCh37
Build 36734,689,680 - 34,689,829RGDNCBI36
Celera734,704,027 - 34,704,176RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,604,342 - 34,604,491UniSTS
CRA_TCAGchr7v2734,767,286 - 34,767,435UniSTS
GeneMap99-GB4 RH Map7155.51UniSTS
Whitehead-RH Map7111.9UniSTS
NCBI RH Map7529.2UniSTS
GPR154__7542  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,889,178 - 34,889,743UniSTSGRCh37
Build 36734,855,703 - 34,856,268RGDNCBI36
Celera734,870,924 - 34,871,489RGD
HuRef734,770,978 - 34,771,543UniSTS
CRA_TCAGchr7v2734,934,185 - 34,934,750UniSTS
G16040  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,786,275 - 34,786,402UniSTSGRCh37
Build 36734,752,800 - 34,752,927RGDNCBI36
Celera734,767,149 - 34,767,276RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,667,224 - 34,667,351UniSTS
CRA_TCAGchr7v2734,830,400 - 34,830,527UniSTS
GDB:3755015  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37734,875,312 - 34,875,372UniSTSGRCh37
Build 36734,841,837 - 34,841,897RGDNCBI36
Celera734,857,060 - 34,857,120RGD
Cytogenetic Map7p14.3UniSTS
HuRef734,757,114 - 34,757,174UniSTS
CRA_TCAGchr7v2734,920,321 - 34,920,381UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
96 498 157 143 1888 192 271 1 77 172 39 193 837 489 2 1773 105 644 216 45 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_012185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001300933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001300934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001300935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_207172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_207173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AACC02000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY255536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY310332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY956446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY956447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY956448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BK005424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ272236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF458424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000359791   ⟹   ENSP00000352839
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,285 - 34,878,332 (+)Ensembl
Ensembl Acc Id: ENST00000360581   ⟹   ENSP00000353788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,218 - 34,849,978 (+)Ensembl
Ensembl Acc Id: ENST00000381539   ⟹   ENSP00000370950
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,409 - 34,849,668 (+)Ensembl
Ensembl Acc Id: ENST00000381542   ⟹   ENSP00000370953
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,285 - 34,849,978 (+)Ensembl
Ensembl Acc Id: ENST00000381544   ⟹   ENSP00000370955
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,285 - 34,849,978 (+)Ensembl
Ensembl Acc Id: ENST00000381553   ⟹   ENSP00000370965
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,239 - 34,779,840 (+)Ensembl
Ensembl Acc Id: ENST00000396095   ⟹   ENSP00000379402
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,285 - 34,849,978 (+)Ensembl
Ensembl Acc Id: ENST00000465305   ⟹   ENSP00000434955
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,285 - 34,686,156 (+)Ensembl
Ensembl Acc Id: ENST00000531252   ⟹   ENSP00000433258
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl734,658,285 - 34,878,332 (+)Ensembl
RefSeq Acc Id: NM_001300933   ⟹   NP_001287862
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38734,658,218 - 34,878,332 (+)NCBI
CHM1_1734,697,875 - 34,917,510 (+)NCBI
T2T-CHM13v2.0734,798,021 - 35,019,005 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001300934   ⟹   NP_001287863
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38734,658,218 - 34,849,978 (+)NCBI
CHM1_1734,697,875 - 34,889,156 (+)NCBI
T2T-CHM13v2.0734,798,021 - 34,990,651 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001300935   ⟹   NP_001287864
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38734,658,218 - 34,849,978 (+)NCBI
CHM1_1734,697,875 - 34,889,156 (+)NCBI
T2T-CHM13v2.0734,798,021 - 34,990,651 (+)NCBI
Sequence:
RefSeq Acc Id: NM_207172   ⟹   NP_997055
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38734,658,218 - 34,849,978 (+)NCBI
GRCh37734,697,897 - 34,917,944 (+)ENTREZGENE
Build 36734,664,422 - 34,856,115 (+)NCBI Archive
HuRef734,579,047 - 34,799,739 (+)ENTREZGENE
CHM1_1734,697,921 - 34,889,156 (+)NCBI
T2T-CHM13v2.0734,798,021 - 34,990,651 (+)NCBI
CRA_TCAGchr7v2734,742,034 - 34,962,952 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_207173   ⟹   NP_997056
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38734,658,218 - 34,878,332 (+)NCBI
GRCh37734,697,897 - 34,917,944 (+)ENTREZGENE
Build 36734,664,422 - 34,884,469 (+)NCBI Archive
HuRef734,579,047 - 34,799,739 (+)ENTREZGENE
CHM1_1734,697,921 - 34,917,510 (+)NCBI
T2T-CHM13v2.0734,798,021 - 35,019,005 (+)NCBI
CRA_TCAGchr7v2734,742,034 - 34,962,952 (+)ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001287862 (Get FASTA)   NCBI Sequence Viewer  
  NP_001287863 (Get FASTA)   NCBI Sequence Viewer  
  NP_001287864 (Get FASTA)   NCBI Sequence Viewer  
  NP_997055 (Get FASTA)   NCBI Sequence Viewer  
  NP_997056 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI32694 (Get FASTA)   NCBI Sequence Viewer  
  AAI32696 (Get FASTA)   NCBI Sequence Viewer  
  AAI44381 (Get FASTA)   NCBI Sequence Viewer  
  AAO85048 (Get FASTA)   NCBI Sequence Viewer  
  AAQ76966 (Get FASTA)   NCBI Sequence Viewer  
  AAQ76967 (Get FASTA)   NCBI Sequence Viewer  
  AAQ76968 (Get FASTA)   NCBI Sequence Viewer  
  AAQ76969 (Get FASTA)   NCBI Sequence Viewer  
  AAQ76970 (Get FASTA)   NCBI Sequence Viewer  
  AAQ76971 (Get FASTA)   NCBI Sequence Viewer  
  AAQ76972 (Get FASTA)   NCBI Sequence Viewer  
  AAX63744 (Get FASTA)   NCBI Sequence Viewer  
  AAX63745 (Get FASTA)   NCBI Sequence Viewer  
  AAX63746 (Get FASTA)   NCBI Sequence Viewer  
  ABB72550 (Get FASTA)   NCBI Sequence Viewer  
  BAD18811 (Get FASTA)   NCBI Sequence Viewer  
  DAA64839 (Get FASTA)   NCBI Sequence Viewer  
  EAL24469 (Get FASTA)   NCBI Sequence Viewer  
  EAL24470 (Get FASTA)   NCBI Sequence Viewer  
  EAW94034 (Get FASTA)   NCBI Sequence Viewer  
  EAW94035 (Get FASTA)   NCBI Sequence Viewer  
  EAW94036 (Get FASTA)   NCBI Sequence Viewer  
  EAW94037 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000352839
  ENSP00000352839.1
  ENSP00000353788
  ENSP00000353788.1
  ENSP00000370950
  ENSP00000370950.3
  ENSP00000370953
  ENSP00000370953.1
  ENSP00000370955.2
  ENSP00000370965.3
  ENSP00000379402.2
  ENSP00000433258
  ENSP00000433258.1
  ENSP00000434955.1
GenBank Protein Q6W5P4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_997056   ⟸   NM_207173
- Peptide Label: isoform B
- UniProtKB: A0A090N8G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_997055   ⟸   NM_207172
- Peptide Label: isoform A
- UniProtKB: Q6W5P3 (UniProtKB/Swiss-Prot),   Q6JSL8 (UniProtKB/Swiss-Prot),   Q6JSL7 (UniProtKB/Swiss-Prot),   Q6JSL6 (UniProtKB/Swiss-Prot),   Q6JSL5 (UniProtKB/Swiss-Prot),   Q6JSL4 (UniProtKB/Swiss-Prot),   Q56H78 (UniProtKB/Swiss-Prot),   Q56H77 (UniProtKB/Swiss-Prot),   Q56H76 (UniProtKB/Swiss-Prot),   Q2XP58 (UniProtKB/Swiss-Prot),   A2RTZ4 (UniProtKB/Swiss-Prot),   Q6ZMB8 (UniProtKB/Swiss-Prot),   Q6W5P4 (UniProtKB/Swiss-Prot),   A0A090N8Z1 (UniProtKB/TrEMBL),   A0A090N8G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001287862   ⟸   NM_001300933
- Peptide Label: isoform B short
- UniProtKB: A0A090N8G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001287864   ⟸   NM_001300935
- Peptide Label: isoform G
- UniProtKB: A0A090N8G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001287863   ⟸   NM_001300934
- Peptide Label: isoform F
- UniProtKB: B7ZMA2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000352839   ⟸   ENST00000359791
Ensembl Acc Id: ENSP00000434955   ⟸   ENST00000465305
Ensembl Acc Id: ENSP00000353788   ⟸   ENST00000360581
Ensembl Acc Id: ENSP00000433258   ⟸   ENST00000531252
Ensembl Acc Id: ENSP00000370950   ⟸   ENST00000381539
Ensembl Acc Id: ENSP00000370955   ⟸   ENST00000381544
Ensembl Acc Id: ENSP00000370953   ⟸   ENST00000381542
Ensembl Acc Id: ENSP00000370965   ⟸   ENST00000381553
Ensembl Acc Id: ENSP00000379402   ⟸   ENST00000396095
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6W5P4-F1-model_v2 AlphaFold Q6W5P4 1-371 view protein structure

Promoters
RGD ID:7210355
Promoter ID:EPDNEW_H10924
Type:initiation region
Name:NPSR1_1
Description:neuropeptide S receptor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38734,658,315 - 34,658,375EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:23631 AgrOrtholog
COSMIC NPSR1 COSMIC
Ensembl Genes ENSG00000187258 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000359791 ENTREZGENE
  ENST00000359791.5 UniProtKB/Swiss-Prot
  ENST00000360581 ENTREZGENE
  ENST00000360581.6 UniProtKB/Swiss-Prot
  ENST00000381539 ENTREZGENE
  ENST00000381539.3 UniProtKB/Swiss-Prot
  ENST00000381542 ENTREZGENE
  ENST00000381542.5 UniProtKB/Swiss-Prot
  ENST00000381544.6 UniProtKB/Swiss-Prot
  ENST00000381553.7 UniProtKB/Swiss-Prot
  ENST00000396095.6 UniProtKB/Swiss-Prot
  ENST00000465305.5 UniProtKB/Swiss-Prot
  ENST00000531252 ENTREZGENE
  ENST00000531252.5 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000187258 GTEx
HGNC ID HGNC:23631 ENTREZGENE
Human Proteome Map NPSR1 Human Proteome Map
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NPS_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vasoprsn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:387129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 387129 ENTREZGENE
OMIM 608595 OMIM
PANTHER NEUROPEPTIDE S RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24244:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134951416 PharmGKB
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VASOPRESSINR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A090N8G9 ENTREZGENE, UniProtKB/TrEMBL
  A0A090N8Z1 ENTREZGENE, UniProtKB/TrEMBL
  A2RTZ4 ENTREZGENE
  B7ZMA2 ENTREZGENE, UniProtKB/TrEMBL
  NPSR1_HUMAN UniProtKB/Swiss-Prot
  Q2XP58 ENTREZGENE
  Q56H76 ENTREZGENE
  Q56H77 ENTREZGENE
  Q56H78 ENTREZGENE
  Q6JSL4 ENTREZGENE
  Q6JSL5 ENTREZGENE
  Q6JSL6 ENTREZGENE
  Q6JSL7 ENTREZGENE
  Q6JSL8 ENTREZGENE
  Q6W5P3 ENTREZGENE
  Q6W5P4 ENTREZGENE
  Q6ZMB8 ENTREZGENE
UniProt Secondary A2RTZ4 UniProtKB/Swiss-Prot
  Q2XP58 UniProtKB/Swiss-Prot
  Q56H76 UniProtKB/Swiss-Prot
  Q56H77 UniProtKB/Swiss-Prot
  Q56H78 UniProtKB/Swiss-Prot
  Q6JSL4 UniProtKB/Swiss-Prot
  Q6JSL5 UniProtKB/Swiss-Prot
  Q6JSL6 UniProtKB/Swiss-Prot
  Q6JSL7 UniProtKB/Swiss-Prot
  Q6JSL8 UniProtKB/Swiss-Prot
  Q6W5P3 UniProtKB/Swiss-Prot
  Q6ZMB8 UniProtKB/Swiss-Prot