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Gene: MTSS1 (MTSS I-BAR domain containing 1) Homo sapiens
Symbol: MTSS1
Name: MTSS I-BAR domain containing 1
Description: Exhibits actin monomer binding activity; identical protein binding activity; and signaling receptor binding activity. Predicted to be involved in cellular response to fluid shear stress; negative regulation of epithelial cell proliferation; and urogenital system development. Localizes to the actin cytoskeleton; PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH 14-Deoxy-11,12-didehydroandrographolide; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp781P2223; FLJ44694; KIAA0429; metastasis suppressor 1; metastasis suppressor protein 1; metastasis suppressor YGL-1; MIM; MIMA; MIMB; missing in metastasis protein; MTSS1, I-BAR domain containing
Mus musculus (house mouse) : Mtss1 (MTSS I-BAR domain containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mtss1 (MTSS I-BAR domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtss1 (MTSS I-BAR domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MTSS1 (MTSS I-BAR domain containing 1)
Canis lupus familiaris (dog) : MTSS1 (MTSS I-BAR domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtss1 (MTSS I-BAR domain containing 1)
Sus scrofa (pig) : MTSS1 (MTSS I-BAR domain containing 1)
Chlorocebus sabaeus (green monkey) : MTSS1 (MTSS I-BAR domain containing 1)
Heterocephalus glaber (naked mole-rat) : Mtss1 (MTSS I-BAR domain containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8124,550,790 - 124,728,429 (-)Ensembl
GRCh388124,550,770 - 124,728,507 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378125,563,025 - 125,740,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368125,632,206 - 125,809,911 (-)NCBINCBI36hg18NCBI36
Build 348125,632,211 - 125,809,840NCBI
Celera8121,751,140 - 121,928,858 (-)NCBI
Cytogenetic Map8q24.13NCBI
HuRef8120,888,491 - 121,064,564 (-)NCBIHuRef
CHM1_18125,603,254 - 125,781,001 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MTSS1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320466
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.