MMP3 (matrix metallopeptidase 3) - Rat Genome Database

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Gene: MMP3 (matrix metallopeptidase 3) Homo sapiens
Symbol: MMP3
Name: matrix metallopeptidase 3
RGD ID: 1345848
Description: Enables endopeptidase activity and metallopeptidase activity. Involved in several processes, including cellular response to UV-A; negative regulation of hydrogen peroxide metabolic process; and positive regulation of protein-containing complex assembly. Predicted to be located in cytosol and mitochondrion. Implicated in several diseases, including artery disease (multiple); carcinoma (multiple); end stage renal disease; osteoarthritis; and von Hippel-Lindau disease. Biomarker of several diseases, including Takayasu's arteritis; arthritis (multiple); autoimmune disease (multiple); conjunctivochalasis; and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CHDS6; matrix metallopeptidase 3 (stromelysin 1, progelatinase); matrix metalloproteinase 3 (stromelysin 1, progelatinase); matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP-3; proteoglycanase; SL-1; STMY; STMY1; STR1; stromelysin-1; transin-1
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl11102,835,801 - 102,843,609 (-)EnsemblGRCh38hg38GRCh38
GRCh3811102,835,801 - 102,843,609 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,706,532 - 102,714,340 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,211,738 - 102,219,552 (-)NCBINCBI36hg18NCBI36
Build 3411102,211,742 - 102,219,550NCBI
Celera1199,868,135 - 99,875,949 (-)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,634,450 - 98,642,264 (-)NCBIHuRef
CHM1_111102,589,497 - 102,597,317 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Otitis Media  (ISO)
allergic contact dermatitis  (ISO)
Alport syndrome  (IEP)
arteriosclerosis  (IAGP)
ataxia telangiectasia  (IAGP)
atrial fibrillation  (IAGP)
breast cancer  (IAGP)
Breast Neoplasms  (EXP)
Carotid Artery Injuries  (ISO)
carotid stenosis  (IAGP)
cartilage disease  (ISO)
cataract  (IEP)
celiac disease  (EXP)
Cerebral Hemorrhage  (EXP)
Chronic Allograft Nephropathy  (IEP)
cognitive disorder  (ISO)
colon cancer  (ISO)
Colorectal Neoplasms  (IAGP)
congestive heart failure  (IEP)
conjunctivochalasis  (IEP)
coronary artery disease  (EXP,IAGP)
Coronary Disease  (EXP,IAGP)
coronary restenosis  (EXP)
crescentic glomerulonephritis  (ISO)
degenerative disc disease  (ISO)
diabetes mellitus  (IEP)
Diabetic Nephropathies  (IEP)
dry eye syndrome  (ISO)
end stage renal disease  (IAGP)
Endotoxemia  (ISO)
esophagus adenocarcinoma  (IAGP)
Experimental Arthritis  (EXP,ISO)
Experimental Liver Cirrhosis  (ISO)
gastric ulcer  (ISO)
glomerulonephritis  (IEP,ISO)
Gouty Arthritis  (IEP)
Hyperalgesia  (EXP,ISO)
Hypoxia-Ischemia, Brain  (ISO)
idiopathic pulmonary fibrosis  (EXP,IEP)
immunoglobulin light chain amyloidosis  (IEP)
intellectual disability  (IAGP)
Knee Osteoarthritis  (ISO)
lung cancer  (IEP)
lymphangioleiomyomatosis  (ISO)
Lymphatic Metastasis  (IAGP)
malignant astrocytoma  (EXP)
Mammary Neoplasms, Experimental  (ISO)
myocardial infarction  (IAGP)
Neoplasm Invasiveness  (EXP)
Neoplasm Metastasis  (ISO)
osteoarthritis  (IDA,IEP)
Parkinsonism  (ISO)
periodontitis  (ISO)
Peripheral Nerve Injuries  (ISO)
peripheral nervous system disease  (EXP)
polymyalgia rheumatica  (IEP)
primary biliary cholangitis  (ISO)
psoriatic arthritis  (IEP)
pulmonary fibrosis  (ISO)
pulmonary tuberculosis  (EXP)
renal cell carcinoma  (IAGP)
Reperfusion Injury  (ISO)
rheumatoid arthritis  (IEP)
Sjogren's syndrome  (IEP)
Stroke  (ISO)
systemic scleroderma  (IDA,IEP)
Takayasu's arteritis  (IEP)
Tendon Injuries  (ISO)
thrombosis  (IAGP)
Transplant Rejection  (IEP)
type 2 diabetes mellitus  (ISO)
Ulcer  (IEP)
Venous Thrombosis  (ISO)
von Hippel-Lindau disease  (IAGP)
Wounds, Penetrating  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-citrinin  (EXP)
(R)-lipoic acid  (EXP)
(S)-nicotine  (EXP)
1,2-dichloroethane  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-hydroxypropanoic acid  (EXP)
3,4-dichloroaniline  (ISO)
3-hydroxypicolinic acid  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3-phenylprop-2-enal  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-nitroquinoline N-oxide  (ISO)
5-aminolevulinic acid  (EXP)
5-chloro-7-iodoquinolin-8-ol  (EXP)
5-fluorouracil  (EXP)
5-iodotubercidin  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP)
acetylsalicylic acid  (ISO)
aflatoxin B1  (EXP)
aldehydo-D-glucosamine  (EXP,ISO)
all-trans-retinoic acid  (EXP)
alpha-naphthoflavone  (ISO)
aluminium oxide  (EXP)
ammonium chloride  (ISO)
anandamide  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antirheumatic drug  (EXP)
arsenite(3-)  (ISO)
avobenzone  (EXP)
azathioprine  (EXP)
azithromycin  (EXP)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
beta-D-glucosamine  (EXP,ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
BQ 123  (EXP)
Butylparaben  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (EXP)
calcitriol  (EXP)
carbon nanotube  (ISO)
chloramphenicol  (EXP)
chlorothalonil  (EXP)
choline  (ISO)
chondroitin sulfate  (EXP)
ciprofloxacin  (EXP)
cisplatin  (EXP)
cobalt atom  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP,ISO)
crotonaldehyde  (EXP)
curcumin  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
dibenzo[a,l]pyrene  (EXP,ISO)
dieckol  (EXP)
diethyl maleate  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
disulfiram  (EXP)
diuron  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (EXP,ISO)
EC (phospholipase A2) inhibitor  (EXP)
enalapril  (ISO)
endosulfan  (EXP,ISO)
enzacamene  (ISO)
ethanol  (ISO)
farnesol  (EXP)
fluoranthene  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (EXP)
fucoidan  (EXP)
gemcitabine  (EXP)
genistein  (ISO)
geraniol  (EXP)
glycitein  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
graphene oxide  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (EXP)
hydroquinone  (EXP)
ibuprofen  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
L-proline betaine  (EXP)
lipoic acid  (EXP)
lipopolysaccharide  (EXP)
lovastatin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
megestrol acetate  (ISO)
melittin  (EXP)
Methanandamide  (EXP)
methotrexate  (EXP)
methylisothiazolinone  (EXP)
mibolerone  (EXP)
mifepristone  (EXP,ISO)
minocycline  (ISO)
moxifloxacin  (EXP)
N-acetyl-L-cysteine  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (EXP,ISO)
nickel sulfate  (EXP,ISO)
nicotine  (EXP)
NSC 23766  (ISO)
ofloxacin  (ISO)
ozone  (ISO)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PD 168393  (EXP)
phenethyl caffeate  (ISO)
phenobarbital  (EXP)
phenytoin  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (EXP)
pravastatin  (EXP)
prinomastat  (EXP)
progesterone  (EXP,ISO)
prostaglandin E2  (ISO)
quercetin  (EXP)
rac-lactic acid  (EXP)
resorcinol  (EXP)
resveratrol  (EXP,ISO)
rifampicin  (EXP)
rofecoxib  (EXP)
rotenone  (EXP)
SB 203580  (EXP)
serpentine asbestos  (EXP,ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
simvastatin  (EXP,ISO)
sodium arsenite  (EXP)
sodium azide  (EXP)
sodium dodecyl sulfate  (EXP)
Soman  (ISO)
streptozocin  (EXP,ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (ISO)
tetracycline  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
tofacitinib  (EXP)
triclosan  (EXP)
tunicamycin  (EXP)
zerumbone  (EXP)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View

References - curated
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Additional References at PubMed
PMID:2383557   PMID:2605216   PMID:2785989   PMID:3030290   PMID:3360803   PMID:3477804   PMID:7523391   PMID:7656014   PMID:7694569   PMID:7998967   PMID:8125298   PMID:8216228  
PMID:8486377   PMID:8535233   PMID:8662692   PMID:8740360   PMID:8804434   PMID:8921407   PMID:8957070   PMID:9083493   PMID:9148753   PMID:9288970   PMID:9548733   PMID:9558113  
PMID:9573338   PMID:9733482   PMID:9737711   PMID:9760240   PMID:9792098   PMID:9827994   PMID:9873489   PMID:9888835   PMID:10419448   PMID:10422833   PMID:10543949   PMID:10639284  
PMID:10669564   PMID:10877850   PMID:10922468   PMID:10947989   PMID:10967118   PMID:10986281   PMID:11116068   PMID:11297453   PMID:11327577   PMID:11375993   PMID:11380116   PMID:11438501  
PMID:11485914   PMID:11546917   PMID:11751414   PMID:11824472   PMID:11827795   PMID:11836255   PMID:11841344   PMID:11841844   PMID:11977998   PMID:11982752   PMID:11988625   PMID:12009331  
PMID:12034345   PMID:12034715   PMID:12054564   PMID:12054629   PMID:12071839   PMID:12103254   PMID:12124858   PMID:12149192   PMID:12204805   PMID:12205736   PMID:12229968   PMID:12230559  
PMID:12385578   PMID:12432557   PMID:12473595   PMID:12477932   PMID:12477941   PMID:12485468   PMID:12572877   PMID:12634064   PMID:12651627   PMID:12727228   PMID:12736398   PMID:12750310  
PMID:12761889   PMID:12784383   PMID:12810672   PMID:12821236   PMID:12832381   PMID:12834347   PMID:12837283   PMID:12866026   PMID:12867428   PMID:12876636   PMID:12880418   PMID:12952836  
PMID:13129650   PMID:14712311   PMID:14715248   PMID:14718574   PMID:14984923   PMID:14998290   PMID:15009479   PMID:15033492   PMID:15070833   PMID:15084374   PMID:15094779   PMID:15102660  
PMID:15142265   PMID:15172469   PMID:15194213   PMID:15203551   PMID:15234427   PMID:15274394   PMID:15288468   PMID:15290728   PMID:15308783   PMID:15312099   PMID:15319302   PMID:15337261  
PMID:15342709   PMID:15355616   PMID:15383690   PMID:15389640   PMID:15474069   PMID:15489334   PMID:15528217   PMID:15529384   PMID:15546966   PMID:15610507   PMID:15640153   PMID:15665388  
PMID:15667946   PMID:15701845   PMID:15716694   PMID:15748780   PMID:15757531   PMID:15763339   PMID:15788677   PMID:15863497   PMID:15879464   PMID:15894268   PMID:15944607   PMID:15955221  
PMID:15972662   PMID:15993717   PMID:16080875   PMID:16082623   PMID:16088212   PMID:16102106   PMID:16202315   PMID:16238676   PMID:16278009   PMID:16302209   PMID:16311244   PMID:16323393  
PMID:16344560   PMID:16356191   PMID:16405530   PMID:16424284   PMID:16430740   PMID:16516860   PMID:16532917   PMID:16615041   PMID:16629857   PMID:16677108   PMID:16739355   PMID:16802342  
PMID:16822591   PMID:16871440   PMID:16899023   PMID:16904077   PMID:16905683   PMID:16919028   PMID:16935611   PMID:16937230   PMID:16972019   PMID:16972255   PMID:16972994   PMID:16984617  
PMID:16998253   PMID:17000679   PMID:17000887   PMID:17003494   PMID:17024375   PMID:17027562   PMID:17033924   PMID:17065356   PMID:17077200   PMID:17137622   PMID:17145822   PMID:17151781  
PMID:17178858   PMID:17181997   PMID:17182940   PMID:17198194   PMID:17207965   PMID:17316652   PMID:17316907   PMID:17319946   PMID:17320799   PMID:17373931   PMID:17381556   PMID:17383306  
PMID:17434489   PMID:17436000   PMID:17471097   PMID:17473191   PMID:17502998   PMID:17530713   PMID:17537400   PMID:17543900   PMID:17559909   PMID:17564313   PMID:17589947   PMID:17607721  
PMID:17617834   PMID:17617837   PMID:17664256   PMID:17669621   PMID:17672933   PMID:17703334   PMID:17710450   PMID:17719307   PMID:17763214   PMID:17763953   PMID:17765638   PMID:17875574  
PMID:17901377   PMID:17911432   PMID:17919326   PMID:17922906   PMID:17929133   PMID:17942123   PMID:17958893   PMID:17975717   PMID:18006768   PMID:18007247   PMID:18028894   PMID:18029348  
PMID:18035073   PMID:18063811   PMID:18076359   PMID:18077489   PMID:18091353   PMID:18172013   PMID:18212480   PMID:18220784   PMID:18225577   PMID:18234553   PMID:18237197   PMID:18262287  
PMID:18275497   PMID:18303200   PMID:18308831   PMID:18342317   PMID:18363112   PMID:18426080   PMID:18445105   PMID:18469698   PMID:18485900   PMID:18496696   PMID:18513389   PMID:18541955  
PMID:18566588   PMID:18571835   PMID:18573993   PMID:18606478   PMID:18609140   PMID:18619594   PMID:18634015   PMID:18636124   PMID:18674944   PMID:18674955   PMID:18760468   PMID:18801353  
PMID:18810583   PMID:18818437   PMID:18818748   PMID:18830194   PMID:18974705   PMID:19005290   PMID:19008710   PMID:19019335   PMID:19019896   PMID:19022250   PMID:19042922   PMID:19056482  
PMID:19064570   PMID:19065524   PMID:19100060   PMID:19131662   PMID:19132754   PMID:19155066   PMID:19159011   PMID:19165649   PMID:19180518   PMID:19212832   PMID:19238444   PMID:19245826  
PMID:19263529   PMID:19268777   PMID:19275880   PMID:19279308   PMID:19293200   PMID:19318431   PMID:19336475   PMID:19337798   PMID:19376102   PMID:19381070   PMID:19432148   PMID:19435861  
PMID:19438845   PMID:19479237   PMID:19504098   PMID:19507017   PMID:19507256   PMID:19508478   PMID:19522160   PMID:19527514   PMID:19559392   PMID:19576586   PMID:19578796   PMID:19585142  
PMID:19614693   PMID:19628284   PMID:19643940   PMID:19664242   PMID:19678938   PMID:19690958   PMID:19729601   PMID:19731200   PMID:19762026   PMID:19770597   PMID:19778329   PMID:19786072  
PMID:19789190   PMID:19834535   PMID:19836620   PMID:19843588   PMID:19892918   PMID:19906289   PMID:19913121   PMID:19923455   PMID:19948975   PMID:19949639   PMID:20009418   PMID:20031604  
PMID:20038976   PMID:20082876   PMID:20092902   PMID:20113256   PMID:20142115   PMID:20204402   PMID:20211321   PMID:20215736   PMID:20302034   PMID:20346360   PMID:20359947   PMID:20360864  
PMID:20374310   PMID:20385826   PMID:20435584   PMID:20436380   PMID:20437586   PMID:20452482   PMID:20453000   PMID:20455995   PMID:20467172   PMID:20472558   PMID:20483790   PMID:20484597  
PMID:20485444   PMID:20538124   PMID:20541269   PMID:20574775   PMID:20584750   PMID:20587546   PMID:20609072   PMID:20609440   PMID:20616708   PMID:20622166   PMID:20628086   PMID:20628624  
PMID:20630073   PMID:20640910   PMID:20654099   PMID:20655856   PMID:20672350   PMID:20673868   PMID:20707923   PMID:20708412   PMID:20731042   PMID:20740392   PMID:20802378   PMID:20822909  
PMID:20827277   PMID:20832538   PMID:20853681   PMID:20873121   PMID:20936527   PMID:20942234   PMID:20948207   PMID:20959880   PMID:20969476   PMID:21037509   PMID:21044079   PMID:21048031  
PMID:21103065   PMID:21108787   PMID:21111627   PMID:21113741   PMID:21134112   PMID:21150162   PMID:21183746   PMID:21187770   PMID:21190865   PMID:21206012   PMID:21212676   PMID:21219546  
PMID:21227015   PMID:21228692   PMID:21232745   PMID:21244504   PMID:21247370   PMID:21277817   PMID:21321996   PMID:21330369   PMID:21336947   PMID:21345293   PMID:21357403   PMID:21410539  
PMID:21431945   PMID:21443102   PMID:21451793   PMID:21454617   PMID:21454822   PMID:21481333   PMID:21601886   PMID:21667159   PMID:21707906   PMID:21753786   PMID:21770773   PMID:21782982  
PMID:21802713   PMID:21853476   PMID:21867693   PMID:21872914   PMID:21873635   PMID:21900582   PMID:21917825   PMID:21925226   PMID:21935932   PMID:21948134   PMID:22027013   PMID:22057989  
PMID:22089392   PMID:22092736   PMID:22114952   PMID:22121090   PMID:22122951   PMID:22134873   PMID:22175304   PMID:22184093   PMID:22204652   PMID:22207289   PMID:22210296   PMID:22222271  
PMID:22241750   PMID:22265821   PMID:22278305   PMID:22323068   PMID:22441965   PMID:22455335   PMID:22457004   PMID:22515887   PMID:22531699   PMID:22587600   PMID:22628530   PMID:22671570  
PMID:22730240   PMID:22776467   PMID:22786680   PMID:22819245   PMID:22832961   PMID:22836729   PMID:22862420   PMID:22868188   PMID:22888638   PMID:22890115   PMID:22922035   PMID:22927007  
PMID:22965799   PMID:22975753   PMID:23043898   PMID:23108733   PMID:23123160   PMID:23128460   PMID:23328930   PMID:23343931   PMID:23357697   PMID:23377317   PMID:23409137   PMID:23412981  
PMID:23483952   PMID:23509928   PMID:23522322   PMID:23548063   PMID:23564449   PMID:23575435   PMID:23608488   PMID:23637955   PMID:23696797   PMID:23705892   PMID:23707809   PMID:23744166  
PMID:23744893   PMID:23752352   PMID:23769926   PMID:23794948   PMID:23845380   PMID:23872201   PMID:23922934   PMID:23926017   PMID:23934131   PMID:23936524   PMID:23941979   PMID:23967200  
PMID:23975061   PMID:23978194   PMID:24043512   PMID:24079541   PMID:24101259   PMID:24111521   PMID:24146820   PMID:24168165   PMID:24338609   PMID:24349530   PMID:24374826   PMID:24414606  
PMID:24416274   PMID:24464212   PMID:24489939   PMID:24507680   PMID:24577893   PMID:24583398   PMID:24667918   PMID:24670135   PMID:24799419   PMID:24804215   PMID:24850902   PMID:24939159  
PMID:24999605   PMID:25049354   PMID:25135219   PMID:25135220   PMID:25147433   PMID:25168209   PMID:25177880   PMID:25217476   PMID:25263962   PMID:25291965   PMID:25292126   PMID:25292349  
PMID:25340798   PMID:25351421   PMID:25391977   PMID:25403368   PMID:25416956   PMID:25463899   PMID:25482733   PMID:25564266   PMID:25599395   PMID:25605062   PMID:25611261   PMID:25711032  
PMID:25742789   PMID:25807652   PMID:25818544   PMID:25854159   PMID:25912212   PMID:25933064   PMID:25993872   PMID:26087627   PMID:26109466   PMID:26123623   PMID:26125893   PMID:26156043  
PMID:26186194   PMID:26191285   PMID:26206176   PMID:26260627   PMID:26314579   PMID:26437765   PMID:26510114   PMID:26526578   PMID:26528997   PMID:26634533   PMID:26681054   PMID:26712881  
PMID:26713439   PMID:26754027   PMID:26805660   PMID:26850593   PMID:26853425   PMID:26863055   PMID:27013197   PMID:27043485   PMID:27051023   PMID:27061553   PMID:27072559   PMID:27089651  
PMID:27108649   PMID:27129069   PMID:27145630   PMID:27161754   PMID:27173221   PMID:27176648   PMID:27177702   PMID:27206651   PMID:27211292   PMID:27268637   PMID:27389714   PMID:27391467  
PMID:27423606   PMID:27438616   PMID:27611862   PMID:27639333   PMID:27659327   PMID:27659332   PMID:27706715   PMID:27733582   PMID:27771306   PMID:27793533   PMID:27797337   PMID:27837634  
PMID:27911281   PMID:27975070   PMID:28002595   PMID:28024290   PMID:28158775   PMID:28160256   PMID:28337851   PMID:28365812   PMID:28396463   PMID:28432524   PMID:28445942   PMID:28447732  
PMID:28461705   PMID:28497435   PMID:28514442   PMID:28521653   PMID:28676856   PMID:28718374   PMID:28781337   PMID:28798935   PMID:28819304   PMID:28831065   PMID:28843428   PMID:28850021  
PMID:28912710   PMID:28914997   PMID:28944430   PMID:28961241   PMID:29044936   PMID:29070037   PMID:29120572   PMID:29141665   PMID:29164307   PMID:29165854   PMID:29172775   PMID:29276151  
PMID:29304854   PMID:29317790   PMID:29358561   PMID:29390034   PMID:29421776   PMID:29442475   PMID:29458338   PMID:29462373   PMID:29483840   PMID:29670668   PMID:29738289   PMID:29883760  
PMID:30031401   PMID:30036111   PMID:30117779   PMID:30138480   PMID:30187662   PMID:30288688   PMID:30297859   PMID:30406565   PMID:30422384   PMID:30509760   PMID:30732526   PMID:30755371  
PMID:30856693   PMID:31055827   PMID:31081124   PMID:31124320   PMID:31208828   PMID:31218540   PMID:31356534   PMID:31377584   PMID:31380578   PMID:31396295   PMID:31467432   PMID:31525531  
PMID:31652448   PMID:31808123   PMID:31827179   PMID:31882488   PMID:31887330   PMID:31894328   PMID:32093874   PMID:32157746   PMID:32272349   PMID:32325785   PMID:32417757   PMID:32421262  
PMID:32450244   PMID:32603484   PMID:32610117   PMID:32945390   PMID:33170424   PMID:33337838   PMID:33531109   PMID:34198485  


Comparative Map Data
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl11102,835,801 - 102,843,609 (-)EnsemblGRCh38hg38GRCh38
GRCh3811102,835,801 - 102,843,609 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,706,532 - 102,714,340 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,211,738 - 102,219,552 (-)NCBINCBI36hg18NCBI36
Build 3411102,211,742 - 102,219,550NCBI
Celera1199,868,135 - 99,875,949 (-)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,634,450 - 98,642,264 (-)NCBIHuRef
CHM1_111102,589,497 - 102,597,317 (-)NCBICHM1_1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3997,445,822 - 7,455,975 (+)NCBIGRCm39mm39
GRCm39 Ensembl97,445,822 - 7,455,975 (+)Ensembl
GRCm3897,445,822 - 7,455,975 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl97,445,822 - 7,455,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv3797,445,822 - 7,455,975 (+)NCBIGRCm37mm9NCBIm37
MGSCv3697,445,822 - 7,455,975 (+)NCBImm8
Celera94,846,374 - 4,856,527 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.284,640,397 - 4,653,963 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl84,640,416 - 4,653,961 (+)Ensembl
Rnor_6.085,676,608 - 5,698,579 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,676,665 - 5,698,579 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,680,382 - 5,701,427 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.484,315,601 - 4,329,146 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.184,315,600 - 4,329,146 (+)NCBI
Celera86,200,234 - 6,213,783 (+)NCBICelera
Cytogenetic Map8q11NCBI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.111101,267,561 - 101,275,432 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,267,566 - 101,275,354 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01197,776,729 - 97,784,549 (-)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1528,949,631 - 28,957,915 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl528,949,631 - 28,958,222 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha528,898,123 - 28,906,399 (+)NCBI
ROS_Cfam_1.0529,000,797 - 29,009,079 (+)NCBI
UMICH_Zoey_3.1529,035,847 - 29,044,131 (+)NCBI
UNSW_CanFamBas_1.0528,915,267 - 28,923,546 (+)NCBI
UU_Cfam_GSD_1.0529,090,249 - 29,098,533 (+)NCBI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1194,216,156 - 94,224,437 (-)NCBI
ChlSab1.1 Ensembl194,216,173 - 94,224,264 (-)Ensembl
Vero_WHO_p1.0NW_02366604331,654,560 - 31,662,871 (+)NCBI
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_00462487839,282 - 47,386 (+)NCBI

Position Markers
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711102,706,653 - 102,706,848UniSTSGRCh37
Build 3611102,211,863 - 102,212,058RGDNCBI36
Celera1199,868,260 - 99,868,455RGD
Cytogenetic Map11q22.2UniSTS
Cytogenetic Map11q22.3UniSTS
HuRef1198,634,575 - 98,634,770UniSTS
Stanford-G3 RH Map114507.0UniSTS
NCBI RH Map11891.8UniSTS
GeneMap99-G3 RH Map114507.0UniSTS
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711102,706,594 - 102,706,896UniSTSGRCh37
Build 3611102,211,804 - 102,212,106RGDNCBI36
Celera1199,868,201 - 99,868,503RGD
Cytogenetic Map11q22.2UniSTS
Cytogenetic Map11q22.3UniSTS
HuRef1198,634,516 - 98,634,818UniSTS
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711102,706,659 - 102,706,930UniSTSGRCh37
Build 3611102,211,869 - 102,212,140RGDNCBI36
Celera1199,868,266 - 99,868,537RGD
Cytogenetic Map11q22.2UniSTS
Cytogenetic Map11q22.3UniSTS
HuRef1198,634,581 - 98,634,852UniSTS
GeneMap99-GB4 RH Map11352.42UniSTS
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711102,706,338 - 102,706,986UniSTSGRCh37
Build 3611102,211,548 - 102,212,196RGDNCBI36
Celera1199,867,945 - 99,868,593RGD
HuRef1198,634,260 - 98,634,908UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:321
Count of miRNA genes:286
Interacting mature miRNAs:300
Transcripts:ENST00000299855, ENST00000434103, ENST00000524478
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 3 24 71 1 31 1 3 24 21 47
Medium 319 157 46 126 41 3 1493 338 426 19 62 60 124 278 1121
Low 1311 619 308 61 166 46 1739 803 376 54 327 427 20 1 338 1099 1 2
Below cutoff 706 1580 897 186 743 185 890 874 1945 152 862 801 4 477 484 1


Nucleotide Sequences
RefSeq Transcripts NG_012100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF405705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI628953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK223283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK223291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP000789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC074815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC074869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA982602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ399598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT355692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT355693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M30460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S52369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U78045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X05232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000299855   ⟹   ENSP00000299855
RefSeq Status:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl11102,835,801 - 102,843,609 (-)Ensembl
RefSeq Acc Id: ENST00000434103   ⟹   ENSP00000398346
RefSeq Status:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl11102,836,497 - 102,838,710 (-)Ensembl
RefSeq Acc Id: ENST00000524478   ⟹   ENSP00000435255
RefSeq Status:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl11102,842,252 - 102,843,607 (-)Ensembl
RefSeq Acc Id: NM_002422   ⟹   NP_002413
RefSeq Status: REVIEWED
Human AssemblyChrPosition (strand)Source
GRCh3811102,835,801 - 102,843,609 (-)NCBI
GRCh3711102,706,528 - 102,714,342 (-)ENTREZGENE
Build 3611102,211,738 - 102,219,552 (-)NCBI Archive
HuRef1198,634,450 - 98,642,264 (-)ENTREZGENE
CHM1_111102,589,497 - 102,597,395 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_002413   ⟸   NM_002422
- Peptide Label: preproprotein
- UniProtKB: P08254 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000299855   ⟸   ENST00000299855
RefSeq Acc Id: ENSP00000435255   ⟸   ENST00000524478
RefSeq Acc Id: ENSP00000398346   ⟸   ENST00000434103
Protein Domains

RGD ID:6849896
Promoter ID:EP30051
Type:single initiation site
Description:Stromelysin, MMP3 or STMY1 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database,
Notes:homology_group=Homology group 173; Mammalian transin/stromelysin.
Experiment Methods:Primer extension with homologous sequence ladder; Nuclease protection; experiments performed with closely related; gene
Regulation:fibroblasts; (induced by or strongly expressed in) IL (repressed by or weakly expressed in) 1b', (repressed by or weakly expressed in) glucocorticoid
Human AssemblyChrPosition (strand)Source
Build 3611102,219,550 - 102,219,610EPD
RGD ID:7221927
Promoter ID:EPDNEW_H16709
Type:initiation region
Description:matrix metallopeptidase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Human AssemblyChrPosition (strand)Source
GRCh3811102,843,607 - 102,843,667EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
MMP3, -1171 5A/6A, PROMOTER variation Coronary heart disease 6 [RCV000013637] Chr11:11q23 risk factor
GRCh38/hg38 11q14.1-22.3(chr11:78232836-106779420)x1 copy number loss See cases [RCV000052710] Chr11:78232836..106779420 [GRCh38]
Chr11:77943882..106650146 [GRCh37]
Chr11:77621530..106155356 [NCBI36]
GRCh38/hg38 11q14.1-22.2(chr11:85242847-102920097)x1 copy number loss See cases [RCV000052711] Chr11:85242847..102920097 [GRCh38]
Chr11:84953891..102738968 [GRCh37]
Chr11:84631539..102296037 [NCBI36]
GRCh38/hg38 11q22.1-25(chr11:100348599-135040246)x3 copy number gain See cases [RCV000053638] Chr11:100348599..135040246 [GRCh38]
Chr11:100219331..134910140 [GRCh37]
Chr11:99724541..134415350 [NCBI36]
NM_002422.3(MMP3):c.921G>T (p.Leu307=) single nucleotide variant Malignant melanoma [RCV000069136] Chr11:102840122 [GRCh38]
Chr11:102710853 [GRCh37]
Chr11:102216063 [NCBI36]
not provided
NM_002422.3(MMP3):c.558C>T (p.Ala186=) single nucleotide variant Malignant melanoma [RCV000069137] Chr11:102842221 [GRCh38]
Chr11:102712952 [GRCh37]
Chr11:102218162 [NCBI36]
not provided
NM_002422.3(MMP3):c.165G>A (p.Lys55=) single nucleotide variant Malignant melanoma [RCV000069138] Chr11:102842857 [GRCh38]
Chr11:102713588 [GRCh37]
Chr11:102218798 [NCBI36]
not provided
GRCh38/hg38 11q22.1-22.3(chr11:98357901-106059146)x1 copy number loss See cases [RCV000136574] Chr11:98357901..106059146 [GRCh38]
Chr11:98228629..105929873 [GRCh37]
Chr11:97733839..105435083 [NCBI36]
GRCh38/hg38 11q22.1-22.3(chr11:101452984-104044105)x3 copy number gain See cases [RCV000136846] Chr11:101452984..104044105 [GRCh38]
Chr11:101323715..103914833 [GRCh37]
Chr11:100828925..103420043 [NCBI36]
GRCh38/hg38 11q14.3-22.3(chr11:91086659-109595582)x1 copy number loss See cases [RCV000138038] Chr11:91086659..109595582 [GRCh38]
Chr11:90819827..109466308 [GRCh37]
Chr11:90459475..108971518 [NCBI36]
GRCh37/hg19 11q22.2(chr11:102642841-102826187)x1 copy number loss See cases [RCV000448411] Chr11:102642841..102826187 [GRCh37]
uncertain significance
NM_002422.5(MMP3):c.626-14A>G single nucleotide variant not specified [RCV000454459] Chr11:102840607 [GRCh38]
Chr11:102711338 [GRCh37]
NM_002422.5(MMP3):c.133A>G (p.Lys45Glu) single nucleotide variant not specified [RCV000454524] Chr11:102842889 [GRCh38]
Chr11:102713620 [GRCh37]
NM_002422.5(MMP3):c.306C>G (p.Thr102=) single nucleotide variant not specified [RCV000454940] Chr11:102842716 [GRCh38]
Chr11:102713447 [GRCh37]
NM_002422.5(MMP3):c.1086T>C (p.Ala362=) single nucleotide variant not specified [RCV000455579] Chr11:102838694 [GRCh38]
Chr11:102709425 [GRCh37]
NM_002422.5(MMP3):c.288T>C (p.Asp96=) single nucleotide variant not specified [RCV000455590] Chr11:102842734 [GRCh38]
Chr11:102713465 [GRCh37]
GRCh37/hg19 11q14.2-22.3(chr11:88152458-109414650)x1 copy number loss See cases [RCV000510457] Chr11:88152458..109414650 [GRCh37]
GRCh37/hg19 11q22.1-22.3(chr11:98515900-104970876)x1 copy number loss See cases [RCV000511844] Chr11:98515900..104970876 [GRCh37]
likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
GRCh37/hg19 11q22.2-22.3(chr11:102578709-107230611)x1 copy number loss not provided [RCV000683366] Chr11:102578709..107230611 [GRCh37]
likely pathogenic
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
GRCh37/hg19 11q14.1-23.2(chr11:80053454-113316236)x1 copy number loss not provided [RCV000737595] Chr11:80053454..113316236 [GRCh37]
NM_002422.5(MMP3):c.126C>T (p.Tyr42=) single nucleotide variant not provided [RCV000936548] Chr11:102842896 [GRCh38]
Chr11:102713627 [GRCh37]
likely benign
NM_002422.5(MMP3):c.792A>G (p.Gly264=) single nucleotide variant not provided [RCV000950210] Chr11:102840251 [GRCh38]
Chr11:102710982 [GRCh37]
NM_002422.5(MMP3):c.12T>A (p.Leu4=) single nucleotide variant not provided [RCV000886546] Chr11:102843535 [GRCh38]
Chr11:102714266 [GRCh37]
likely benign
NM_002422.5(MMP3):c.249T>C (p.Thr83=) single nucleotide variant not provided [RCV000881514] Chr11:102842773 [GRCh38]
Chr11:102713504 [GRCh37]
NM_002422.5(MMP3):c.1131C>T (p.His377=) single nucleotide variant not provided [RCV000962222] Chr11:102838649 [GRCh38]
Chr11:102709380 [GRCh37]
NM_002422.5(MMP3):c.457T>C (p.Tyr153His) single nucleotide variant not provided [RCV000960056] Chr11:102842473 [GRCh38]
Chr11:102713204 [GRCh37]
likely benign
NM_002422.5(MMP3):c.58T>C (p.Leu20=) single nucleotide variant not provided [RCV000960121] Chr11:102843489 [GRCh38]
Chr11:102714220 [GRCh37]
NM_002422.5(MMP3):c.1305A>G (p.Ser435=) single nucleotide variant not provided [RCV000910672] Chr11:102837326 [GRCh38]
Chr11:102708057 [GRCh37]
likely benign
NM_002422.5(MMP3):c.228G>A (p.Thr76=) single nucleotide variant not provided [RCV000908648] Chr11:102842794 [GRCh38]
Chr11:102713525 [GRCh37]
NM_002422.5(MMP3):c.858G>T (p.Thr286=) single nucleotide variant not provided [RCV000962223] Chr11:102840185 [GRCh38]
Chr11:102710916 [GRCh37]
NM_002422.5(MMP3):c.480G>T (p.Met160Ile) single nucleotide variant not provided [RCV000930687] Chr11:102842450 [GRCh38]
Chr11:102713181 [GRCh37]
likely benign
NM_002422.5(MMP3):c.478A>T (p.Met160Leu) single nucleotide variant not provided [RCV000971018] Chr11:102842452 [GRCh38]
Chr11:102713183 [GRCh37]
likely benign
NM_002422.5(MMP3):c.711C>T (p.Tyr237=) single nucleotide variant not provided [RCV000934455] Chr11:102840508 [GRCh38]
Chr11:102711239 [GRCh37]
likely benign
Single allele single nucleotide variant not provided [RCV001358154] Chr11:102847936 [GRCh38]
Chr11:102718667 [GRCh37]
uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
NC_000011.9:g.(?_94153285)_(111965700_?)del deletion Ataxia-telangiectasia syndrome [RCV001389105] Chr11:94153285..111965700 [GRCh37]

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:7173 AgrOrtholog
Ensembl Genes ENSG00000149968 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000299855 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000398346 UniProtKB/TrEMBL
  ENSP00000435255 UniProtKB/TrEMBL
Ensembl Transcript ENST00000299855 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000434103 UniProtKB/TrEMBL
  ENST00000524478 UniProtKB/TrEMBL
Gene3D-CATH UniProtKB/TrEMBL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/Swiss-Prot
GTEx ENSG00000149968 GTEx
Human Proteome Map MMP3 Human Proteome Map
InterPro Hemopexin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/Swiss-Prot
  M10A_MMP UniProtKB/Swiss-Prot
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot
  Pept_M10_metallopeptidase UniProtKB/Swiss-Prot
  Pept_M10A UniProtKB/Swiss-Prot
  Pept_M10A_Zn_BS UniProtKB/Swiss-Prot
  Peptidase_Metallo UniProtKB/Swiss-Prot
  Peptidoglycan-bd-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:4314 UniProtKB/Swiss-Prot
OMIM 185250 OMIM
  614466 OMIM
Pfam Hemopexin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/Swiss-Prot
  PG_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/Swiss-Prot
  HEMOPEXIN UniProtKB/Swiss-Prot
  HEMOPEXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART SM00120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnMc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47090 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Secondary B2R8B8 UniProtKB/Swiss-Prot
  Q3B7S0 UniProtKB/Swiss-Prot
  Q6GRF8 UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-03 MMP3  matrix metallopeptidase 3    matrix metallopeptidase 3 (stromelysin 1, progelatinase)  Symbol and/or name change 5135510 APPROVED
2011-08-16 MMP3  matrix metallopeptidase 3 (stromelysin 1, progelatinase)  MMP3  matrix metallopeptidase 3 (stromelysin 1, progelatinase)  Symbol and/or name change 5135510 APPROVED