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Gene: ITPA (inosine triphosphatase) Homo sapiens
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Symbol: ITPA
Name: inosine triphosphatase
Description: Exhibits identical protein binding activity. Predicted to be involved in nucleoside triphosphate catabolic process. Localizes to the cytosol and nuclear body. Implicated in several diseases, including anemia (multiple); early infantile epileptic encephalopathy 35; hepatitis C; precursor lymphoblastic lymphoma/leukemia; and rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C20orf37; dJ794I6.3; EIEE35; HLC14-06-P; inosine triphosphatase (nucleoside triphosphate pyrophosphatase); inosine triphosphatase-A; inosine triphosphate pyrophosphatase; inosine triphosphate pyrophosphohydrolase; ITPase; My049; non-canonical purine NTP pyrophosphatase; non-standard purine NTP pyrophosphatase; NTPase; nucleoside triphosphate diphosphatase; nucleoside-triphosphate diphosphatase; nucleoside-triphosphate pyrophosphatase; putative oncogene protein HLC14-06-P
Orthologs:
Mus musculus (house mouse) : Itpa (inosine triphosphatase (nucleoside triphosphate pyrophosphatase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Itpa (inosine triphosphatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itpa (inosine triphosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : ITPA (inosine triphosphatase)
Canis lupus familiaris (dog) : ITPA (inosine triphosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itpa (inosine triphosphatase)
Sus scrofa (pig) : ITPA (inosine triphosphatase)
Chlorocebus sabaeus (African green monkey) : ITPA (inosine triphosphatase)
Heterocephalus glaber (naked mole-rat) : Itpa (inosine triphosphatase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl203,208,868 - 3,223,870 (+)EnsemblGRCh38hg38GRCh38
GRCh38203,208,676 - 3,227,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37203,189,514 - 3,204,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,138,056 - 3,152,506 (+)NCBINCBI36hg18NCBI36
Build 34203,138,055 - 3,152,504NCBI
Celera203,252,018 - 3,266,469 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef203,137,390 - 3,152,825 (+)NCBIHuRef
CHM1_1203,189,574 - 3,208,157 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ITPA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348154
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.