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Gene: CCL21 (C-C motif chemokine ligand 21) Homo sapiens
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Symbol: CCL21
Name: C-C motif chemokine ligand 21
RGD ID: 1323745
Description: Exhibits chemokine activity. Involved in several processes, including positive regulation of cellular component biogenesis; positive regulation of intracellular signal transduction; and regulation of leukocyte migration. Predicted to localize to extracellular space. Biomarker of pulmonary fibrosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6Ckine; beta chemokine exodus-2; beta-chemokine exodus-2; C-C motif chemokine 21; chemokine (C-C motif) ligand 21; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus-2; MGC34555; SCYA21; secondary lymphoid tissue chemokine; secondary lymphoid-tissue chemokine; SLC; small inducible cytokine subfamily A (Cys-Cys), member 21; small-inducible cytokine A21; TCA4
Orthologs:
Mus musculus (house mouse) : Ccl21a (chemokine (C-C motif) ligand 21A (serine))  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccl21 (C-C motif chemokine ligand 21)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccl21 (C-C motif chemokine ligand 21)
Pan paniscus (bonobo/pygmy chimpanzee) : CCL21 (C-C motif chemokine ligand 21)
Canis lupus familiaris (dog) : CCL21 (C-C motif chemokine ligand 21)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccl21 (C-C motif chemokine ligand 21)
Sus scrofa (pig) : CCL21 (C-C motif chemokine ligand 21)
Heterocephalus glaber (naked mole-rat) : Ccl21 (C-C motif chemokine ligand 21)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl934,709,005 - 34,710,136 (-)EnsemblGRCh38hg38GRCh38
GRCh38934,709,005 - 34,710,136 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37934,709,002 - 34,710,164 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36934,699,002 - 34,700,147 (-)NCBINCBI36hg18NCBI36
Build 34934,699,001 - 34,700,147NCBI
Celera934,640,475 - 34,641,620 (-)NCBI
Cytogenetic Map9p13.3NCBI
HuRef934,663,256 - 34,664,418 (-)NCBIHuRef
CHM1_1934,708,790 - 34,709,952 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CCL21
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323745
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.