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Gene: PHIP (pleckstrin homology domain interacting protein) Homo sapiens
Symbol: PHIP
Name: pleckstrin homology domain interacting protein
Description: Exhibits lysine-acetylated histone binding activity. Involved in several processes, including negative regulation of extrinsic apoptotic signaling pathway; positive regulation of transcription by RNA polymerase II; and regulation of cell morphogenesis. Predicted to localize to nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BRWD2; CHUJANS; DCAF14; DDB1 and CUL4 associated factor 14; DIDOD; FLJ20705; FLJ45918; IRS-1 PH domain-binding protein; MGC90216; ndrp; PH-interacting protein; WD repeat-containing protein 11; WDR11
Mus musculus (house mouse) : Phip (pleckstrin homology domain interacting protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Phip (pleckstrin homology domain interacting protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phip (pleckstrin homology domain interacting protein)
Pan paniscus (bonobo/pygmy chimpanzee) : PHIP (pleckstrin homology domain interacting protein)
Canis lupus familiaris (dog) : PHIP (pleckstrin homology domain interacting protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phip (pleckstrin homology domain interacting protein)
Sus scrofa (pig) : PHIP (pleckstrin homology domain interacting protein)
Chlorocebus sabaeus (African green monkey) : PHIP (pleckstrin homology domain interacting protein)
Heterocephalus glaber (naked mole-rat) : Phip (pleckstrin homology domain interacting protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl678,934,419 - 79,078,254 (-)EnsemblGRCh38hg38GRCh38
GRCh38678,934,419 - 79,078,294 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37679,644,136 - 79,788,011 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36679,706,985 - 79,844,708 (-)NCBINCBI36hg18NCBI36
Build 34679,707,001 - 79,844,708NCBI
Celera680,031,409 - 80,175,293 (-)NCBI
Cytogenetic Map6q14.1NCBI
HuRef676,837,993 - 76,981,618 (-)NCBIHuRef
CHM1_1679,741,711 - 79,885,530 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PHIP
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1345138
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.