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Gene: IL3 (interleukin 3) Homo sapiens
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Symbol: IL3
Name: interleukin 3
Description: Predicted to have interleukin-3 receptor binding activity. Involved in embryonic hemopoiesis; positive regulation of cell population proliferation; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to extracellular space. Implicated in Graves' disease; asthma; and rheumatoid arthritis. Biomarker of several diseases, including Alzheimer's disease; Ebola hemorrhagic fever; genital herpes; major depressive disorder; and obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: colony-stimulating factor, multiple; hematopoietic growth factor; IL-3; interleukin-3; mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MULTI-CSF; multilineage-colony-stimulating factor; multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor
Orthologs:
Mus musculus (house mouse) : Il3 (interleukin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il3 (interleukin 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : IL3 (interleukin 3)
Canis lupus familiaris (dog) : IL3 (interleukin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il3 (interleukin 3)
Chlorocebus sabaeus (African green monkey) : IL3 (interleukin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5132,060,655 - 132,063,204 (+)EnsemblGRCh38hg38GRCh38
GRCh385132,060,655 - 132,063,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,396,347 - 131,398,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,424,246 - 131,426,795 (+)NCBINCBI36hg18NCBI36
Build 345131,424,245 - 131,426,795NCBI
Celera5127,526,422 - 127,528,971 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5126,588,706 - 126,591,255 (+)NCBIHuRef
CHM1_15130,829,174 - 130,831,722 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IL3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737391
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.