IL3 (interleukin 3) - Rat Genome Database

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Gene: IL3 (interleukin 3) Homo sapiens
Analyze
Symbol: IL3
Name: interleukin 3
RGD ID: 737391
HGNC Page HGNC:6011
Description: Enables cytokine activity. Involved in several processes, including embryonic hemopoiesis; interleukin-3-mediated signaling pathway; and positive regulation of tyrosine phosphorylation of STAT protein. Is active in extracellular space. Implicated in Graves ophthalmopathy; Graves' disease; asthma; and rheumatoid arthritis. Biomarker of several diseases, including Ebola hemorrhagic fever; genital herpes; major depressive disorder; obesity; and psoriasis.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: colony-stimulating factor, multiple; hematopoietic growth factor; IL-3; interleukin-3; mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MULTI-CSF; multilineage-colony-stimulating factor; multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,060,655 - 132,063,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,060,655 - 132,063,204 (+)EnsemblGRCh38hg38GRCh38
GRCh375131,396,348 - 131,398,897 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,424,246 - 131,426,795 (+)NCBINCBI36Build 36hg18NCBI36
Build 345131,424,245 - 131,426,795NCBI
Celera5127,526,422 - 127,528,971 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5126,588,706 - 126,591,255 (+)NCBIHuRef
CHM1_15130,829,174 - 130,831,722 (+)NCBICHM1_1
T2T-CHM13v2.05132,580,524 - 132,583,073 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-chloro-2,4-dinitrobenzene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (EXP)
5-fluorouracil  (ISO)
acrolein  (ISO)
aflatoxin B1  (EXP)
alclometasone dipropionate  (EXP)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
aspartame  (EXP)
beclomethasone  (EXP)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP)
benzoates  (ISO)
betamethasone valerate  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
Calcimycin  (ISO)
cannabidiol  (ISO)
capsaicin  (ISO)
chloroquine  (ISO)
ciprofloxacin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP)
dioxygen  (ISO)
emamectin benzoate  (EXP)
entinostat  (ISO)
ethanol  (EXP)
formaldehyde  (ISO)
hydralazine  (EXP)
ionomycin  (EXP)
lipopolysaccharide  (ISO)
luteolin  (ISO)
methotrexate  (EXP,ISO)
microcystin-LR  (ISO)
monodansylcadaverine  (ISO)
mycophenolic acid  (ISO)
N-acetyl-L-cysteine  (EXP)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
naproxen  (ISO)
neocuproine  (ISO)
nonanoic acid  (ISO)
p-menthan-3-ol  (EXP)
paracetamol  (EXP)
paraquat  (ISO)
phenylarsine oxide  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
resveratrol  (EXP,ISO)
sirolimus  (ISO)
sterigmatocystin  (ISO)
sumatriptan  (ISO)
tacrolimus hydrate  (EXP,ISO)
tert-butyl hydroperoxide  (EXP)
theophylline  (EXP)
titanium dioxide  (ISO)
TMC-120A  (ISO)
toluene 2,4-diisocyanate  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
wortmannin  (EXP)
zidovudine  (ISO)
zinc atom  (EXP)
zinc dichloride  (ISO)
zinc oxide  (ISO)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell apoptotic process  (ISO)
B cell proliferation  (ISO)
cell population proliferation  (ISO)
cell-cell signaling  (TAS)
cytokine-mediated signaling pathway  (ISO)
embryonic hemopoiesis  (IDA)
extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
hematopoietic progenitor cell differentiation  (ISO)
hemopoiesis  (ISO)
immune response  (IEA)
interleukin-3-mediated signaling pathway  (IDA,ISO)
JNK cascade  (ISO)
mast cell apoptotic process  (ISO)
mast cell proliferation  (ISO)
monocyte differentiation  (ISO)
myeloid cell apoptotic process  (ISO)
myeloid leukocyte differentiation  (ISO)
negative regulation of autophagy  (ISO)
negative regulation of B cell apoptotic process  (ISO)
negative regulation of mast cell apoptotic process  (ISO)
negative regulation of myeloid cell apoptotic process  (ISO)
nervous system development  (TAS)
positive regulation of B cell proliferation  (ISO)
positive regulation of cell population proliferation  (IDA,ISO,ISS,TAS)
positive regulation of hematopoietic progenitor cell differentiation  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of mast cell proliferation  (ISO)
positive regulation of myeloid leukocyte differentiation  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO,ISS)
positive regulation of protein phosphorylation  (ISO)
positive regulation of T cell proliferation  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (IDA)
regulation of cell growth  (ISO)
regulation of gene expression  (ISO)
regulation of glycolytic process  (ISO)
regulation of protein dephosphorylation  (ISO)
response to hormone  (ISO)
response to hypoxia  (ISO)
signal transduction  (IEA)
T cell proliferation  (ISO)

Cellular Component
extracellular region  (IEA,TAS)
extracellular space  (IDA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Schizophrenia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Adenovirus-mediated interleukin 3 beta gene transfer by isolated limb perfusion inhibits growth of limb sarcoma in rats. de Wilt JH, etal., Hum Gene Ther. 2001 Mar 20;12(5):489-502.
2. A dual role for the immune response in a mouse model of inflammation-associated lung cancer. Dougan M, etal., J Clin Invest. 2011 Jun 1;121(6):2436-46. doi: 10.1172/JCI44796. Epub 2011 May 2.
3. Strongyloides ratti infection induces transient nematode-specific Th2 response and reciprocal suppression of IFN-gamma production in mice. Eschbach ML, etal., Parasite Immunol. 2010 May;32(5):370-83.
4. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
5. Identification of a 5-protein biomarker molecular signature for predicting Alzheimer's disease. Gomez Ravetti M and Moscato P, PLoS One. 2008 Sep 3;3(9):e3111.
6. The cytokine response to human traumatic brain injury: temporal profiles and evidence for cerebral parenchymal production. Helmy A, etal., J Cereb Blood Flow Metab. 2011 Feb;31(2):658-70. Epub 2010 Aug 18.
7. Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes. Huang CH, etal., BMC Proc. 2009 Dec 15;3 Suppl 7:S75.
8. Global gene expression profiling of renal scarring in a rat model of pyelonephritis. Ichino M, etal., Pediatr Nephrol. 2008 Jul;23(7):1059-71. Epub 2008 Jan 23.
9. IL3 SNP rs40401 variant is a risk factor for rhinoconjunctivitis in Japanese women: the Kyushu Okinawa maternal and child health study. Miyake Y, etal., Cytokine. 2013 Oct;64(1):86-9. doi: 10.1016/j.cyto.2013.07.020. Epub 2013 Aug 15.
10. IL3 rs40401 polymorphism and interaction with smoking in risk of asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health study. Miyake Y, etal., Scand J Immunol. 2014 Jun;79(6):410-4. doi: 10.1111/sji.12171.
11. Hematopoietic cytokines in the sera of patients with pancreatic cancer. Mroczko B, etal., Clin Chem Lab Med. 2005;43(2):146-50.
12. Subcutaneous injection containing IL-3 and GM-CSF ameliorates stab wound-induced brain injury in rats. Nishihara T, etal., Exp Neurol. 2011 Jun;229(2):507-16. Epub 2011 Apr 16.
13. Interleukin 3 (IL3) polymorphisms associated with decreased risk of asthma and atopy. Park BL, etal., J Hum Genet. 2004;49(10):517-27. doi: 10.1007/s10038-004-0184-x. Epub 2004 Sep 11.
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
16. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
17. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Ray S, etal., Nat Med. 2007 Nov;13(11):1359-62. Epub 2007 Oct 14.
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia. Rick FG, etal., Prostate. 2011 May 15;71(7):736-47. doi: 10.1002/pros.21289. Epub 2010 Oct 13.
20. Keratinocytes play a role in the immunity to Herpes simplex virus type 2 infection. Shao Y, etal., Acta Virol. 2010;54(4):261-7.
21. Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. Shelton RC, etal., Mol Psychiatry. 2011 Jul;16(7):751-62. doi: 10.1038/mp.2010.52. Epub 2010 May 18.
22. Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects. van Dijk SJ, etal., PLoS One. 2010 Dec 23;5(12):e14422.
23. Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis. Wauquier N, etal., PLoS Negl Trop Dis. 2010 Oct 5;4(10). pii: e837.
24. Differential cytokine secretion of cultured bone marrow stromal cells from patients with psoriasis and healthy volunteers. Zhang K, etal., Eur J Dermatol. 2010 Jan-Feb;20(1):49-53. Epub 2009 Nov 4.
25. Association analysis of polymorphisms in IL-3, IL-4, IL-5, IL-9, and IL-13 with Graves' disease. Zhu W, etal., J Endocrinol Invest. 2010 Nov;33(10):751-5. Epub 2010 Mar 22.
Additional References at PubMed
PMID:1833064   PMID:2268499   PMID:2544122   PMID:3127463   PMID:3489530   PMID:3497400   PMID:3497843   PMID:7642615   PMID:7957082   PMID:8018916   PMID:8516290   PMID:8649415  
PMID:8676386   PMID:9030599   PMID:9113989   PMID:9209414   PMID:9278420   PMID:9551928   PMID:9629242   PMID:9659156   PMID:9722506   PMID:9736740   PMID:10477722   PMID:10677502  
PMID:11179015   PMID:11399510   PMID:11486081   PMID:11700046   PMID:11714768   PMID:11763346   PMID:11861295   PMID:11994280   PMID:12002675   PMID:12055233   PMID:12089333   PMID:12093816  
PMID:12135758   PMID:12165512   PMID:12423306   PMID:12477932   PMID:12612065   PMID:12759409   PMID:12855588   PMID:12884288   PMID:12943658   PMID:14551608   PMID:14564341   PMID:14615378  
PMID:14628073   PMID:14675189   PMID:14755254   PMID:15060062   PMID:15372022   PMID:15489334   PMID:15576295   PMID:15585837   PMID:15878977   PMID:15988318   PMID:16785501   PMID:17179997  
PMID:17207965   PMID:17273755   PMID:17362254   PMID:17507237   PMID:17541278   PMID:17624239   PMID:17703412   PMID:18633131   PMID:18676680   PMID:18692472   PMID:18768389   PMID:18804346  
PMID:18826654   PMID:18829683   PMID:19074885   PMID:19131452   PMID:19158269   PMID:19170196   PMID:19201898   PMID:19247692   PMID:19258923   PMID:19262575   PMID:19529981   PMID:19578876  
PMID:19625176   PMID:19692168   PMID:19730683   PMID:19829692   PMID:19845895   PMID:19913121   PMID:20147630   PMID:20210668   PMID:20237496   PMID:20381581   PMID:20424473   PMID:20452482  
PMID:20453000   PMID:20472554   PMID:20503287   PMID:20516062   PMID:20628086   PMID:20673868   PMID:20738848   PMID:20800603   PMID:20964623   PMID:21071541   PMID:21102463   PMID:21149635  
PMID:21168724   PMID:21224257   PMID:21262803   PMID:21506110   PMID:21643009   PMID:22321809   PMID:22412388   PMID:22515947   PMID:23024272   PMID:23128233   PMID:23226269   PMID:23726808  
PMID:23978640   PMID:24390342   PMID:24598054   PMID:24658545   PMID:24670917   PMID:25472883   PMID:25766237   PMID:25962901   PMID:26277822   PMID:26299549   PMID:26875095   PMID:27157262  
PMID:27323078   PMID:27443880   PMID:27862234   PMID:28112181   PMID:28344320   PMID:28377320   PMID:28456746   PMID:28705238   PMID:29374162   PMID:29554544   PMID:29724998   PMID:30274838  
PMID:30652781   PMID:30769926   PMID:30804107   PMID:30893922   PMID:30967511   PMID:31175163   PMID:31990690   PMID:32327499   PMID:32889153   PMID:33301029   PMID:34262178   PMID:34506850  
PMID:34619417   PMID:34753904   PMID:35281014   PMID:35559673   PMID:36233301   PMID:36729088   PMID:36911737   PMID:37160117   PMID:37453342   PMID:37759746  


Genomics

Comparative Map Data
IL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,060,655 - 132,063,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,060,655 - 132,063,204 (+)EnsemblGRCh38hg38GRCh38
GRCh375131,396,348 - 131,398,897 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,424,246 - 131,426,795 (+)NCBINCBI36Build 36hg18NCBI36
Build 345131,424,245 - 131,426,795NCBI
Celera5127,526,422 - 127,528,971 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5126,588,706 - 126,591,255 (+)NCBIHuRef
CHM1_15130,829,174 - 130,831,722 (+)NCBICHM1_1
T2T-CHM13v2.05132,580,524 - 132,583,073 (+)NCBIT2T-CHM13v2.0
Il3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391154,155,911 - 54,158,105 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1154,156,129 - 54,158,103 (-)EnsemblGRCm39 Ensembl
GRCm381154,265,085 - 54,267,279 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1154,265,303 - 54,267,277 (-)EnsemblGRCm38mm10GRCm38
MGSCv371154,078,587 - 54,080,781 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,108,726 - 54,110,700 (-)NCBIMGSCv36mm8
Celera1158,854,078 - 58,856,272 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1132.13NCBI
Il3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,906,460 - 38,908,810 (-)NCBIGRCr8
mRatBN7.21038,405,716 - 38,408,066 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1038,405,716 - 38,408,066 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1043,090,254 - 43,092,770 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01042,580,351 - 42,582,867 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01038,084,063 - 38,086,579 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01039,620,535 - 39,622,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1039,620,563 - 39,622,973 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01039,397,782 - 39,400,192 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,684,691 - 39,687,041 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11039,698,313 - 39,700,664 (-)NCBI
Celera1037,746,256 - 37,748,606 (-)NCBICelera
Cytogenetic Map10q22NCBI
IL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24127,379,116 - 127,381,660 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15125,518,679 - 125,521,223 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05127,483,843 - 127,486,388 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15133,647,667 - 133,650,213 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5133,647,667 - 133,650,213 (+)Ensemblpanpan1.1panPan2
IL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,330,480 - 20,332,668 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,330,480 - 20,332,668 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,126,033 - 19,128,221 (+)NCBIDog10K_Boxer_Tasha
UMICH_Zoey_3.11119,835,277 - 19,837,465 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01119,683,253 - 19,685,440 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01120,324,838 - 20,327,026 (+)NCBIUU_Cfam_GSD_1.0
Il3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213116,100,160 - 116,101,996 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366473,102,922 - 3,104,758 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12334,894,630 - 34,899,105 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603443,059,393 - 43,061,627 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in IL3
11 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3 copy number gain See cases [RCV000051193] Chr5:130860928..155321811 [GRCh38]
Chr5:130196621..154701371 [GRCh37]
Chr5:130224520..154681564 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q23.2-31.1(chr5:126438406-132873967)x1 copy number loss See cases [RCV000052109] Chr5:126438406..132873967 [GRCh38]
Chr5:125774098..132209659 [GRCh37]
Chr5:125801997..132237558 [NCBI36]
Chr5:5q23.2-31.1
pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2
pathogenic
GRCh38/hg38 5q23.1-31.1(chr5:116677122-132686163)x1 copy number loss See cases [RCV000053525] Chr5:116677122..132686163 [GRCh38]
Chr5:116012818..132021855 [GRCh37]
Chr5:116040717..132049754 [NCBI36]
Chr5:5q23.1-31.1
pathogenic
GRCh38/hg38 5q31.1(chr5:131626503-135815054)x1 copy number loss See cases [RCV000135442] Chr5:131626503..135815054 [GRCh38]
Chr5:130962196..135150743 [GRCh37]
Chr5:130990095..135178642 [NCBI36]
Chr5:5q31.1
pathogenic
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3 copy number gain See cases [RCV000138808] Chr5:129847794..153353546 [GRCh38]
Chr5:129183487..152733106 [GRCh37]
Chr5:129211386..152713299 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3
likely benign
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)x3 copy number gain See cases [RCV000449349] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV002231249]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2
pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
NC_000005.10:g.(?_131428263)_(132208822_?)del deletion Schizophrenia [RCV000754294] Chr5:131428263..132208822 [GRCh38]
Chr5:5q31.1
likely pathogenic
GRCh37/hg19 5q23.2-31.2(chr5:126377719-136270989)x1 copy number loss not provided [RCV000762739] Chr5:126377719..136270989 [GRCh37]
Chr5:5q23.2-31.2
likely pathogenic
NC_000005.9:g.(?_130497712)_(131729974_?)del deletion Renal carnitine transport defect [RCV001031175] Chr5:130497712..131729974 [GRCh37]
Chr5:5q23.3-31.1
pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32
uncertain significance
NM_000588.4(IL3):c.7C>T (p.Arg3Cys) single nucleotide variant not provided [RCV000963845] Chr5:132060713 [GRCh38]
Chr5:131396406 [GRCh37]
Chr5:5q31.1
benign
NM_000588.4(IL3):c.294+9A>T single nucleotide variant not provided [RCV000888102] Chr5:132062410 [GRCh38]
Chr5:131398103 [GRCh37]
Chr5:5q31.1
benign
NM_000588.4(IL3):c.179A>G (p.Asn60Ser) single nucleotide variant not provided [RCV000893594] Chr5:132060983 [GRCh38]
Chr5:131396676 [GRCh37]
Chr5:5q31.1
likely benign
GRCh37/hg19 5q31.1(chr5:131107107-131528744)x3 copy number gain not provided [RCV000846701] Chr5:131107107..131528744 [GRCh37]
Chr5:5q31.1
uncertain significance
NM_000588.4(IL3):c.189C>T (p.Asp63=) single nucleotide variant not provided [RCV000888101] Chr5:132060993 [GRCh38]
Chr5:131396686 [GRCh37]
Chr5:5q31.1
benign
GRCh37/hg19 5q23.3-31.1(chr5:127800418-134002686) copy number loss Neurodevelopmental disorder and language delay with or without structural brain abnormalities [RCV003236718] Chr5:127800418..134002686 [GRCh37]
Chr5:5q23.3-31.1
pathogenic
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910) copy number gain not specified [RCV002053526] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
NM_000588.4(IL3):c.335C>T (p.Thr112Met) single nucleotide variant Inborn genetic diseases [RCV002822239] Chr5:132062566 [GRCh38]
Chr5:131398259 [GRCh37]
Chr5:5q31.1
uncertain significance
NM_000588.4(IL3):c.182G>A (p.Gly61Glu) single nucleotide variant Inborn genetic diseases [RCV002887274] Chr5:132060986 [GRCh38]
Chr5:131396679 [GRCh37]
Chr5:5q31.1
likely benign
NM_000588.4(IL3):c.352A>G (p.Ile118Val) single nucleotide variant Inborn genetic diseases [RCV002767962] Chr5:132062684 [GRCh38]
Chr5:131398377 [GRCh37]
Chr5:5q31.1
uncertain significance
NM_000588.4(IL3):c.369G>C (p.Trp123Cys) single nucleotide variant Inborn genetic diseases [RCV002787629] Chr5:132062701 [GRCh38]
Chr5:131398394 [GRCh37]
Chr5:5q31.1
uncertain significance
NM_000588.4(IL3):c.380G>T (p.Arg127Leu) single nucleotide variant Inborn genetic diseases [RCV002665006] Chr5:132062712 [GRCh38]
Chr5:131398405 [GRCh37]
Chr5:5q31.1
uncertain significance
NM_000588.4(IL3):c.159G>T (p.Leu53Phe) single nucleotide variant Inborn genetic diseases [RCV002987860] Chr5:132060865 [GRCh38]
Chr5:131396558 [GRCh37]
Chr5:5q31.1
uncertain significance
NM_000588.4(IL3):c.16G>A (p.Val6Ile) single nucleotide variant Inborn genetic diseases [RCV003346916] Chr5:132060722 [GRCh38]
Chr5:131396415 [GRCh37]
Chr5:5q31.1
likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:207
Count of miRNA genes:196
Interacting mature miRNAs:200
Transcripts:ENST00000296870
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D5S2409  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,539 - 131,398,864UniSTSGRCh37
Build 365131,426,438 - 131,426,763RGDNCBI36
Celera5127,528,614 - 127,528,939RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,898 - 126,591,223UniSTS
Stanford-G3 RH Map54959.0UniSTS
GeneMap99-GB4 RH Map5510.84UniSTS
Whitehead-RH Map5414.1UniSTS
Whitehead-YAC Contig Map5 UniSTS
GeneMap99-G3 RH Map55047.0UniSTS
RH17672  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,428 - 131,398,585UniSTSGRCh37
Build 365131,426,327 - 131,426,484RGDNCBI36
Celera5127,528,503 - 127,528,660RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,787 - 126,590,944UniSTS
GeneMap99-GB4 RH Map5509.47UniSTS
SHGC-132106  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,549 - 131,398,845UniSTSGRCh37
Build 365131,426,448 - 131,426,744RGDNCBI36
Celera5127,528,624 - 127,528,920RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,908 - 126,591,204UniSTS
TNG Radiation Hybrid Map560152.0UniSTS
IL3_1962  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,407 - 131,399,080UniSTSGRCh37
Build 365131,426,306 - 131,426,979RGDNCBI36
Celera5127,528,482 - 127,529,155RGD
HuRef5126,590,766 - 126,591,439UniSTS
ECD01182  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,397,819 - 131,398,693UniSTSGRCh37
Build 365131,425,718 - 131,426,592RGDNCBI36
Celera5127,527,894 - 127,528,768RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,178 - 126,591,052UniSTS
ECD09687  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,394,757 - 131,395,379UniSTSGRCh37
Build 365131,422,656 - 131,423,278RGDNCBI36
Celera5127,524,832 - 127,525,454RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,587,116 - 126,587,738UniSTS
ECD10008  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,395,408 - 131,396,021UniSTSGRCh37
Build 365131,423,307 - 131,423,920RGDNCBI36
Celera5127,525,483 - 127,526,096RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,587,767 - 126,588,380UniSTS
ECD10565  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,396,093 - 131,396,691UniSTSGRCh37
Build 365131,423,992 - 131,424,590RGDNCBI36
Celera5127,526,168 - 127,526,766RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,588,452 - 126,589,050UniSTS
ECD14015  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,396,950 - 131,397,453UniSTSGRCh37
Build 365131,424,849 - 131,425,352RGDNCBI36
Celera5127,527,025 - 127,527,528RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,589,309 - 126,589,812UniSTS
ECD19506  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,771 - 131,399,090UniSTSGRCh37
Build 365131,426,670 - 131,426,989RGDNCBI36
Celera5127,528,846 - 127,529,165RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,591,130 - 126,591,449UniSTS
REN68694  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,394,491 - 131,394,744UniSTSGRCh37
Build 365131,422,390 - 131,422,643RGDNCBI36
Celera5127,524,566 - 127,524,819RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,586,850 - 126,587,103UniSTS
REN68695  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,394,725 - 131,394,975UniSTSGRCh37
Build 365131,422,624 - 131,422,874RGDNCBI36
Celera5127,524,800 - 127,525,050RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,587,084 - 126,587,334UniSTS
REN68696  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,394,967 - 131,395,238UniSTSGRCh37
Build 365131,422,866 - 131,423,137RGDNCBI36
Celera5127,525,042 - 127,525,313RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,587,326 - 126,587,597UniSTS
REN68697  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,395,215 - 131,395,453UniSTSGRCh37
Build 365131,423,114 - 131,423,352RGDNCBI36
Celera5127,525,290 - 127,525,528RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,587,574 - 126,587,812UniSTS
REN68698  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,395,430 - 131,395,683UniSTSGRCh37
Build 365131,423,329 - 131,423,582RGDNCBI36
Celera5127,525,505 - 127,525,758RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,587,789 - 126,588,042UniSTS
REN68699  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,395,658 - 131,395,906UniSTSGRCh37
Build 365131,423,557 - 131,423,805RGDNCBI36
Celera5127,525,733 - 127,525,981RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,588,017 - 126,588,265UniSTS
REN68700  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,395,882 - 131,396,129UniSTSGRCh37
Build 365131,423,781 - 131,424,028RGDNCBI36
Celera5127,525,957 - 127,526,204RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,588,241 - 126,588,488UniSTS
REN68701  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,396,116 - 131,396,381UniSTSGRCh37
Build 365131,424,015 - 131,424,280RGDNCBI36
Celera5127,526,191 - 127,526,456RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,588,475 - 126,588,740UniSTS
REN68702  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,396,365 - 131,396,595UniSTSGRCh37
Build 365131,424,264 - 131,424,494RGDNCBI36
Celera5127,526,440 - 127,526,670RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,588,724 - 126,588,954UniSTS
REN68703  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,396,580 - 131,396,833UniSTSGRCh37
Build 365131,424,479 - 131,424,732RGDNCBI36
Celera5127,526,655 - 127,526,908RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,588,939 - 126,589,192UniSTS
REN68704  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,396,832 - 131,397,094UniSTSGRCh37
Build 365131,424,731 - 131,424,993RGDNCBI36
Celera5127,526,907 - 127,527,169RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,589,191 - 126,589,453UniSTS
REN68705  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,397,074 - 131,397,327UniSTSGRCh37
Build 365131,424,973 - 131,425,226RGDNCBI36
Celera5127,527,149 - 127,527,402RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,589,433 - 126,589,686UniSTS
REN68706  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,397,224 - 131,397,450UniSTSGRCh37
Build 365131,425,123 - 131,425,349RGDNCBI36
Celera5127,527,299 - 127,527,525RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,589,583 - 126,589,809UniSTS
REN68707  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,397,607 - 131,397,850UniSTSGRCh37
Build 365131,425,506 - 131,425,749RGDNCBI36
Celera5127,527,682 - 127,527,925RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,589,966 - 126,590,209UniSTS
REN68708  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,397,824 - 131,398,078UniSTSGRCh37
Build 365131,425,723 - 131,425,977RGDNCBI36
Celera5127,527,899 - 127,528,153RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,183 - 126,590,437UniSTS
REN68709  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,055 - 131,398,319UniSTSGRCh37
Build 365131,425,954 - 131,426,218RGDNCBI36
Celera5127,528,130 - 127,528,394RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,414 - 126,590,678UniSTS
REN68710  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,298 - 131,398,542UniSTSGRCh37
Build 365131,426,197 - 131,426,441RGDNCBI36
Celera5127,528,373 - 127,528,617RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,657 - 126,590,901UniSTS
REN68711  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,523 - 131,398,763UniSTSGRCh37
Build 365131,426,422 - 131,426,662RGDNCBI36
Celera5127,528,598 - 127,528,838RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,882 - 126,591,122UniSTS
REN68712  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,739 - 131,398,963UniSTSGRCh37
Build 365131,426,638 - 131,426,862RGDNCBI36
Celera5127,528,814 - 127,529,038RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,591,098 - 126,591,322UniSTS
REN68713  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,940 - 131,399,192UniSTSGRCh37
Build 365131,426,839 - 131,427,091RGDNCBI36
Celera5127,529,015 - 127,529,267RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,591,299 - 126,591,551UniSTS
stSG601023  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,394,448 - 131,395,544UniSTSGRCh37
Build 365131,422,347 - 131,423,443RGDNCBI36
Celera5127,524,523 - 127,525,619RGD
HuRef5126,586,807 - 126,587,903UniSTS
stSG601024  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,395,525 - 131,396,691UniSTSGRCh37
Build 365131,423,424 - 131,424,590RGDNCBI36
Celera5127,525,600 - 127,526,766RGD
HuRef5126,587,884 - 126,589,050UniSTS
stSG601025  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,396,672 - 131,397,839UniSTSGRCh37
Build 365131,424,571 - 131,425,738RGDNCBI36
Celera5127,526,747 - 127,527,914RGD
HuRef5126,589,031 - 126,590,198UniSTS
stSG601026  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,397,827 - 131,399,172UniSTSGRCh37
Build 365131,425,726 - 131,427,071RGDNCBI36
Celera5127,527,902 - 127,529,247RGD
HuRef5126,590,186 - 126,591,531UniSTS
G10621  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,398,573 - 131,398,789UniSTSGRCh37
Build 365131,426,472 - 131,426,688RGDNCBI36
Celera5127,528,648 - 127,528,864RGD
Cytogenetic Map5q31.1UniSTS
HuRef5126,590,932 - 126,591,148UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 1
Low 6 6 7 6 2 2 11 2
Below cutoff 295 453 310 209 177 191 488 225 418 30 406 231 19 82 374

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_000588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC004511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC034228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF365976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI574160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L10616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M17115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M20137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U97676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U97677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U97678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U97679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000296870   ⟹   ENSP00000296870
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5132,060,655 - 132,063,204 (+)Ensembl
RefSeq Acc Id: NM_000588   ⟹   NP_000579
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,060,655 - 132,063,204 (+)NCBI
GRCh375131,396,347 - 131,398,896 (+)ENTREZGENE
Build 365131,424,246 - 131,426,795 (+)NCBI Archive
HuRef5126,588,706 - 126,591,255 (+)ENTREZGENE
CHM1_15130,829,174 - 130,831,722 (+)NCBI
T2T-CHM13v2.05132,580,524 - 132,583,073 (+)NCBI
Sequence:
RefSeq Acc Id: NP_000579   ⟸   NM_000588
- Peptide Label: precursor
- UniProtKB: Q6GS87 (UniProtKB/Swiss-Prot),   P08700 (UniProtKB/Swiss-Prot),   Q6NZ78 (UniProtKB/TrEMBL),   Q6NZ79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000296870   ⟸   ENST00000296870

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P08700-F1-model_v2 AlphaFold P08700 1-152 view protein structure

Promoters
RGD ID:6870536
Promoter ID:EPDNEW_H8412
Type:multiple initiation site
Name:IL3_1
Description:interleukin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,060,656 - 132,060,716EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6011 AgrOrtholog
COSMIC IL3 COSMIC
Ensembl Genes ENSG00000164399 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000296870 ENTREZGENE
  ENST00000296870.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1250.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000164399 GTEx
HGNC ID HGNC:6011 ENTREZGENE
Human Proteome Map IL3 Human Proteome Map
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3562 UniProtKB/Swiss-Prot
NCBI Gene 3562 ENTREZGENE
OMIM 147740 OMIM
PANTHER INTERLEUKIN-3 UniProtKB/Swiss-Prot
  INTERLEUKIN-3 UniProtKB/Swiss-Prot
  INTERLEUKIN-3 UniProtKB/TrEMBL
  INTERLEUKIN-3 UniProtKB/TrEMBL
Pfam IL3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29830 PharmGKB
PIRSF IL-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS INTERLEUKIN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt IL3_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q6GS87 ENTREZGENE
  Q6NZ78 ENTREZGENE, UniProtKB/TrEMBL
  Q6NZ79 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q6GS87 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-15 IL3  interleukin 3  IL3  interleukin 3 (colony-stimulating factor, multiple)  Symbol and/or name change 5135510 APPROVED