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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737391
Species: Homo sapiens
RGD Object: Gene
Symbol: IL3
Name: interleukin 3
Acc ID: CHEBI:46024
Term: trichostatin A
Definition: A trichostatin that has formula 302.36826.
Chemical ID: MESH:C012589
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL3multiple interactionsISOIl3 (Mus musculus)6480464CTDtrichostatin A inhibits the reaction [IL3 protein promotes the reaction [BRD2 protein binds to CISH promoter]]; trichostatin A inhibits the reaction [IL3 protein results in increased expression of CISH mRNA]; trichostatin A inhibits the reaction [IL3 protein results in increased expression of MYC mRNA]; trichostatin A inhibits the reaction [IL3 protein results in increased expression of OSM mRNA]; trichostatin A promotes the reaction [IL3 protein results in increased expression of FOS mRNA]PMID:25769527
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