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Gene: CLEC16A (C-type lectin domain containing 16A) Homo sapiens
Symbol: CLEC16A
Name: C-type lectin domain containing 16A
Description: Predicted to have Rab GTPase binding activity. Involved in cellular response to starvation; negative regulation of macroautophagy; and positive regulation of TORC1 signaling. Localizes to the Golgi apparatus; cytosol; and vesicle. Predicted to colocalize with the late endosome. Implicated in Addison's disease; multiple sclerosis; rheumatoid arthritis; and type 1 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-type lectin domain family 16 member A; C-type lectin domain family 16, member A; Gop-1; KIAA0350; MGC111457
Mus musculus (house mouse) : Clec16a (C-type lectin domain family 16, member A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clec16a (C-type lectin domain containing 16A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clec16a (C-type lectin domain containing 16A)
Pan paniscus (bonobo/pygmy chimpanzee) : CLEC16A (C-type lectin domain containing 16A)
Canis lupus familiaris (dog) : CLEC16A (C-type lectin domain containing 16A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clec16a (C-type lectin domain containing 16A)
Sus scrofa (pig) : CLEC16A (C-type lectin domain containing 16A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381610,944,488 - 11,193,272 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371611,038,345 - 11,276,046 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361610,945,943 - 11,183,539 (+)NCBINCBI36hg18NCBI36
Celera1611,207,780 - 11,445,485 (+)NCBI
Cytogenetic Map16p13.13NCBI
HuRef1610,955,943 - 11,193,891 (+)NCBIHuRef
CHM1_11611,038,266 - 11,275,979 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CLEC16A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604037
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.