GWAS618537_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS618537_H (eosinophil percentage of leukocytes QTL GWAS618537 (human)) Homo sapiens

Symbol: GWAS618537_H
Name: eosinophil percentage of leukocytes QTL GWAS618537 (human)
RGD ID: 406969561
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count to total leukocyte count ratio   (CMO:0000369)    
LOD Score: Not Available
P Value: 6.0E-34
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381611,136,846 - 11,136,847RGD_MAPPER_PIPELINEGRCh38
GRCh371611,230,703 - 11,230,704RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS618537_HHumanblood eosinophil count to total leukocyte count ratio  IAGPrs7203459405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS618537_HHumaneosinophil quantity  IAGPrs7203459405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS618537_HHumaneosinophil percentage of leukocytes  IAGPrs7203459405850206 GWAS_CATALOGPMID:27863252

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1604037CLEC16AC-type lectin domain containing 16A161094456411182186Human


Peak: (rs7203459)
Human AssemblyChrPosition (strand)Source
GRCh381611,136,846 - 11,136,847RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
407229654GWAS878630_Hasthma QTL GWAS878630 (human)4e-15asthma161113684611136847Human
406964583GWAS613559_Hneutrophil percentage of granulocytes QTL GWAS613559 (human)5e-31neutrophil quantity (VT:0000222)161113684611136847Human
597203758GWAS1299832_Hasthma QTL GWAS1299832 (human)4e-18asthma161113684611136847Human
407146188GWAS795164_Hallergic disease QTL GWAS795164 (human)0.0000002allergic disease161113684611136847Human
406969561GWAS618537_Heosinophil percentage of leukocytes QTL GWAS618537 (human)6e-34eosinophil quantity (VT:0002602)blood eosinophil count to total leukocyte count ratio (CMO:0000369)161113684611136847Human
597053036GWAS1149110_Hasthma QTL GWAS1149110 (human)6e-16asthma161113684611136847Human
406973196GWAS622172_Heosinophil percentage of granulocytes QTL GWAS622172 (human)7e-33eosinophil quantity (VT:0002602)161113684611136847Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS618537_H GCST004600 Eosinophil percentage of white cells 172,378 European ancestry individuals C 0.2459 6E-34 33.222 rs7203459 0.05025668 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:27863252
GWAS613559_H GCST004623 Neutrophil percentage of granulocytes 170,672 European ancestry individuals C 0.2458 5E-31 30.302 rs7203459 0.04813 neutrophil percentage of granulocytes (EFO:0007994)
 PMID:27863252
GWAS1149110_H GCST009845 Nonatopic asthma 28,862 European ancestry cases, 422,048 European ancestry controls ? NR 6E-16 15.222 rs7203459 N/A PMID:31669095
GWAS622172_H GCST004617 Eosinophil percentage of granulocytes 170,536 European ancestry individuals C 0.2457 7E-33 32.155 rs7203459 0.04966455 eosinophil percentage of granulocytes (EFO:0007996)
 PMID:27863252
GWAS795164_H GCST002083 Self-reported allergy 53,862 European ancestry individuals C 0.2674 2E-7 6.699 rs7203459 0.0706 PMID:23817569
GWAS1299832_H GCST006911 Asthma (moderate or severe) 5,135 European ancestry cases, 25,675 European ancestry controls T 0.7544 4E-18 17.398 rs7203459 1.1627907 PMID:30552067
GWAS878630_H GCST003987 Asthma 28,399 European ancestry cases, 128,843 European ancestry controls ? NR 4E-15 14.398 rs7203459 1.092 PMID:27182965
Database
Acc Id
Source(s)
GWAS Catalog GCST004600 GWAS Catalog

Note Type Note Reference