GWAS1322538_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1322538_H (asthma, age at onset QTL GWAS1322538 (human)) Homo sapiens

Symbol: GWAS1322538_H
Name: asthma, age at onset QTL GWAS1322538 (human)
RGD ID: 597226464
Trait: asthma, age at onset
LOD Score: Not Available
P Value: 2.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381611,125,184 - 11,125,185RGD_MAPPER_PIPELINEGRCh38
GRCh371611,219,041 - 11,219,042RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1322538_HHumanasthma  IAGPrs12935657405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:30929738

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1322538_HHumanage at onset  IAGPrs12935657405850206 GWAS_CATALOGPMID:30929738

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1604037CLEC16AC-type lectin domain containing 16A161094456411182186Human


Peak: (rs12935657)
Human AssemblyChrPosition (strand)Source
GRCh381611,125,184 - 11,125,185RGD_MAPPER_PIPELINE


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597216858GWAS1312932_Hchildhood onset asthma QTL GWAS1312932 (human)1e-49childhood onset asthma161112518411125185Human
597292058GWAS1388132_Hrespiratory system disease QTL GWAS1388132 (human)2e-52respiratory system disease161112518411125185Human
597144702GWAS1240776_Hage of onset of childhood onset asthma QTL GWAS1240776 (human)3e-27age of onset of childhood onset asthma161112518411125185Human
597227123GWAS1323197_Hasthma QTL GWAS1323197 (human)7e-34asthma161112518411125185Human
597049722GWAS1145796_Hatopic asthma QTL GWAS1145796 (human)1e-25atopic asthma161112518411125185Human
597053447GWAS1149521_Hasthma QTL GWAS1149521 (human)6e-33asthma161112518411125185Human
596953574GWAS1073093_Hrespiratory system disease QTL GWAS1073093 (human)2e-52respiratory system disease161112518411125185Human
597057218GWAS1153292_HEczematoid dermatitis, allergic rhinitis QTL GWAS1153292 (human)1e-38Eczematoid dermatitis, allergic rhinitis161112518411125185Human
597165038GWAS1261112_Hasthma QTL GWAS1261112 (human)3e-16asthma161112518411125185Human
597056686GWAS1152760_Hallergic rhinitis QTL GWAS1152760 (human)8e-15allergic rhinitis161112518411125185Human

1 to 10 of 13 rows


1 to 12 of 12 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1322538_H GCST007797 Asthma onset (childhood vs adult) 13,962 European ancestry childhood onset cases, 14,873 European ancestry adult onset cases G 0.749 2E-7 6.699 rs12935657 1.062 age at onset (EFO:0004847)
 PMID:30929738
GWAS1145796_H GCST009850 Atopic asthma 23,982 European ancestry cases, 393,169 European ancestry controls ? NR 1E-25 25 rs12935657 N/A atopic asthma (EFO:0010638)
 PMID:31669095
GWAS1147670_H GCST009716 Allergic disease (asthma, hay fever or eczema) 106,772 European ancestry cases, 239,773 European ancestry controls G 0.7558 6E-45 44.222 rs12935657 1.0945709 Eczematoid dermatitis (HP:0000964)
allergic rhinitis (EFO:0005854)
 PMID:31361310
GWAS1149521_H GCST009720 Asthma 41,926 European ancestry cases, 239,773 European ancestry controls A 0.2442 6E-33 32.222 rs12935657 N/A PMID:31361310
GWAS1152760_H GCST009719 Allergic rhinitis 18,915 European ancestry cases, 239,773 European ancestry controls G 0.7569 8E-15 14.097 rs12935657 1.1082788 allergic rhinitis (EFO:0005854)
 PMID:31361310
GWAS1153292_H GCST009717 Hay fever and/or eczema 84,034 European ancestry cases, 239,773 European ancestry controls G 0.7558 1E-38 38 rs12935657 1.0955303 Eczematoid dermatitis (HP:0000964)
allergic rhinitis (EFO:0005854)
 PMID:31361310
GWAS1240776_H GCST90255669 Age of onset of childhood onset asthma 20,964 European ancestry cases, 674,014 European ancestry controls ? NR 3E-27 26.523 rs12935657 0.13661 age of onset of childhood onset asthma (OBA:2001015)
 PMID:36778051
GWAS1261112_H GCST90018795 Asthma 38,369 European ancestry cases, 411,131 European ancestry controls, 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls A NR 3E-16 15.523 rs12935657 0.0722 PMID:34594039
GWAS1312932_H GCST007800 Asthma (childhood onset) 13,962 European ancestry cases, 300,671 European ancestry controls ? NR 1E-49 49 rs12935657 1.133 PMID:30929738
GWAS1323197_H GCST007798 Asthma 40,544 European ancestry cases, 300,671 European ancestry controls G NR 7E-34 33.155 rs12935657 1.1 PMID:30929738
GWAS922312_H GCST010043 Asthma 84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls G 0.76 8E-52 51.097 rs12935657 N/A PMID:32296059
GWAS1388132_H GCST90309345 Respiratory disease (confirmatory factor analysis Factor 11) 360,406 European ancestry individuals ? NR 2E-52 51.699 rs12935657 N/A respiratory system disease (EFO:0000684)
 PMID:38965376
1 to 12 of 12 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST007797 GWAS Catalog

Note Type Note Reference